MORII Magotoshi 森井孫俊

… Alternative Names

森井孫俊

Less

Researcher Number	60019130
External Links
Affiliation (based on the past Project Information) *help	2008 – 2011: 鈴鹿医療科学大学, 薬学部, 教授 2007: 富山大学, 医学薬学研究部(薬学), 准教授 2006: 富山大学, 大学院医学薬学研究部, 助教授 2005: Toyama University, Faculty of Pharmaceutical Sciences, Associate professor, 薬学部, 助教授 2002 – 2004: 富山医科薬科大学, 薬学部, 講師 1988: 富山医科薬科大学, 薬学部, 講師
Review Section/Research Field	Except Principal Investigator Biological Sciences / General physiology / Physical pharmacy
Keywords	Except Principal Investigator 胃酸分泌 / プロトンポンプ / 胃酸分泌細胞 / gastric acid secretion / Cl^-チャネル / 細管小胞 / gastric proton pump / 大腸プロトンポンプ / プロトンポンプ阻害剤 / プロテアソーム … More / 胃プロトンポンプ / インターロイキン / 細胞防御 / 能動輸送 / トランスポーター / 塩素イオン / 塩化物イオン / K^+-Cl^-共輸送体 / リン脂質 / トランスポートソーム / コレステロール / カベオソーム / カベオラ / nitric oxide / interleukin / cytoprotection / chloride channel / proton pump inhibitor / gastric flippase / 胃フリツパーゼ / 一酸化窒素 / 塩素イオンチャネル / 胃フリッパーゼ / modeling / active transport / proton pump / nanomachine / ユビチキン / ユビキチン / モデリング / 部位特異的変異導入 / 構造機能相関 / ナノマシーン / Na^+.K^+-ATPase / thromboxane / flippase / acid pump antagonist / proteasome / phosphorvlation / ナトリウムポンプ / イオンポンプ / 遺伝子発現 / 大腸がん / 安定発現細胞 / 大腸 / 分子動力学 / Na^+,K^+-ATPase / トロンボキサン / フリッパーゼ / 酸分泌拮抗薬 / リン酸化 / オメプラゾール / H、K-ATPase / ピロリ菌 / プロスタグランジン / SLC26A9 / SLC26A7 / イオンチャネル / ホメオスタシス / 脂質ラフト / 界面活性剤 / アピカル膜 / H^+,K^+-ATPase / 胃腺 / ベシクル / KCC4 / CLC-5 / 蛋白質 / イオン輸送 / トランスポートそーム / 胃酸分泌機構 / ラフト Less

Clarification of properties of chloride channels, SLC26A7 and 26A9, involved in novel cytoprotective mechanism
- Principal Investigator
  
  SAKAI Hideki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  University of Toyama
3種類の胃プロトンポンプトランスポートソームの機能と環境基盤の解明
- Principal Investigator
  
  酒井秀紀
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Toyama
胃酸分泌細胞の細管小胞融合におけるトランスポートソーム機能の解明
- Principal Investigator
  
  SAKAI Hideki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Toyama
Molecular Physiological Mechanism of Chloride Ion Secretion by CLC-5 and KCC4 associated with Gastric Proton Pump
- Principal Investigator
  
  SAKAI Hideki
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  University of Toyama
Study on the Structure and Mechanism Involved in Functional regulation of Gastric Proton Pump
- Principal Investigator
  
  ASANO Shinji
- Project Period (FY)
  2001 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Ritsumeikan University
  Toyama Medical and Pharmaceutical University
Structure and function of novel pumps and channels in gastrointestinal tract
- Principal Investigator
  
  TAKEGUCHI Noriaki
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
Molecular and functional relations and intracellular polarized movement of the functional molecules in stomach and intestine.
- Principal Investigator
  
  SAKAI Hideki, 竹口紀晃
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Toyama Medical and Pharmaceutical University
H、K-ATPaseの高次構造
- Principal Investigator
  
  TAKEGUCHI Noriaki
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Toyama Medical and Pharmaceutical University

All 2010 2009 2008 2007 2006 2005 2004 2000

All Journal Article Presentation

[Journal Article] イオンポンプ研究の最前線2010
- Author(s)
  森井孫俊、酒井秀紀
- Journal Title
  
  薬学雑誌 130
  
  Pages: 177-177
- NAID
  130000171285
- Data Source
  KAKENHI-PROJECT-20056010
[Journal Article] Involvement of aquaporin-5 in differentiation of human gastric cancer cells2009
- Author(s)
  Watanabe T, Fujii T, Oya T, Horikawa N, Tabuchi Y, Takahashi Y, Morii M, Takeguchi N, Tsukada K, Sakai H.
- Journal Title
  
  J. Physiol. Sci 59
  
  Pages: 113-122
- NAID
  10025218436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390064
[Journal Article] Functional association between K^+-Cl^- cotransporter-4 and H^+,K^+-ATPase in the apical canalicular membrane of gastric parietal cells2009
- Author(s)
  Fujii T, Takahashi Y, Ikari A, Morii M, Tabuchi Y, Tsukada K, Takeguchi N, Sakai H.
- Journal Title
  
  J. Biol. Chem 284
  
  Pages: 619-629
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390064
[Journal Article] Functional consequences of various leucine mutations in the M3/M4 loop of the Na^+,K^+-ATPase α-subunit2008
- Author(s)
  Eguchi H, Morii M, Takahashi Y, Sakai H, Nakano M, Ochiai H, Shirahata A, Hara Y, Kawamura M, Takeda K.
- Journal Title
  
  J. Membr. Biol 221
  
  Pages: 133-140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390064
[Journal Article] Involvement of the H_3O^+-Lys-164-G1n-161-Glu-345 charge transfer pathway in proton transport of gastric H^+, K^+-ATPase.2008
- Author(s)
  Morii M., et.al.
- Journal Title
  
  I. Biol. Chem. 283
  
  Pages: 16876-16884
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20056010
[Journal Article] K^+-Cl^- cotransporter-3a up-regulates Na^+,K^+-ATPase in lipid rafts of gastric luminal parietal cells2008
- Author(s)
  Fujii T, Takahashi Y, Itomi Y, Fujita K, Morii M, Tabuchi Y, Asano S, Tsukada K, Takeguchi N, Sakai H.
- Journal Title
  
  J. Biol. Chem 283
  
  Pages: 6869-6877
- NAID
  120002226796
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390064
[Journal Article] Involvement of the H_3O^+-Lys-164-Gln-161-Glu-345 charge transfer pathway in proton transport of gastric H^+, K^+-ATPase2008
- Author(s)
  Morii M, Yamauchi M, Ichikawa T, Fujii T, Takahashi Y, Asano S, Takeguchi N, Sakai H.
- Journal Title
  
  J. Biol. Chem 283
  
  Pages: 16876-16884
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390064
[Journal Article] Involvement of the H_3O^+-Lys-164-Gln-161-Glu-345 charge transfer pathway in proton transport of gastric H^+, K^+-ATPase.2008
- Author(s)
  Morii M., et al.
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 16876-16884
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390064
[Journal Article] Inhibition of P-type ATPases by [(dihydroindenyl)oxy]acetic acid (DIOA), a K^+-Cl^- cotransporter inhibitor2007
- Author(s)
  Fujii T, Ohira Y, Itomi Y, Takahashi Y, Asano S, Morii M, Takeguchi N, Sakai H.
- Journal Title
  
  Eur. J. Pharmacol 560
  
  Pages: 123-126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390064
[Journal Article] Upregulation of thromboxane synthase in human colorectal carcinoma and the cancer cell proliferation by thromboxane A22006
- Author(s)
  Sakai H, Suzuki T, Takahashi Y, Ukai M, Tauchi K, Fujii T, Horikawa N, Minamimura T, Tabuchi Y, Morii M, Tsukada K, Takeguchi N.
- Journal Title
  
  FEBS Lett 580
  
  Pages: 3368-3374
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390064
[Journal Article] Gastric proton pump and membrane Dynamics.2006
- Author(s)
  Asano, S., Morii, M.
- Journal Title
  
  Membrane (in press)
- NAID
  10017581433
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142202
[Journal Article] Novel molecular mechanisms of gastric phospholipids translocation activity in isolated hog gastric vesicles.2005
- Author(s)
  Morii, M.
- Journal Title
  
  Membrane 30
  
  Pages: 312-317
- NAID
  10016855118
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13142202
[Journal Article] Novel molecular mechanisms of gastric phospholipids translocation activity in isolated hog gastric vesicles.2005
- Author(s)
  Morii M, et al.
- Journal Title
  
  Membrane 30
  
  Pages: 312-317
- NAID
  10016855118
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12144205
[Journal Article] 胃ベシクルにおける膜リン脂質転移の新規分子機構2005
- Author(s)
  森井孫俊
- Journal Title
  
  膜 30(6)
  
  Pages: 312-317
- NAID
  10016855118
- Data Source
  KAKENHI-PROJECT-13142202
[Journal Article] Novel molecular mechanisms of gastric phospho- lipids translocation activity in isolated hog gastric vesicles.2005
- Author(s)
  Morii, M. et al.
- Journal Title
  
  Membrane 30
  
  Pages: 312-317
- NAID
  10016855118
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142202
[Journal Article] The cavity structure for docking the K^+-competitive inhibitors in the gastric proton pump.2004
- Author(s)
  Asano S, Yoshida A, Yashiro H, Kobayashi Y, Morisato A, Ogawa H, Takeguchi N, Morii M.
- Journal Title
  
  Journal of Biological Chemistry 279巻14号
  
  Pages: 13968-13975
- Data Source
  KAKENHI-PROJECT-12144205
[Journal Article] The phospholipid flippase in isolated hog gastric vesicles : Evidence for translocation of endogenous glycerolphospholipids.2000
- Author(s)
  Morii M, et al.
- Journal Title
  
  Membrane 25
  
  Pages: 198-205
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12144205
[Journal Article] Effects of proton pump inhibitors SCH28080, SPI-447 and rabeprazole on the gastric phospholipid flippase activity.2000
- Author(s)
  Morii M, et al.
- Journal Title
  
  Membrane 25
  
  Pages: 324-331
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12144205
[Presentation] 胃プロトンポンプ阻害剤オメプラゾールとSCH28080は結合ポケットを共有する2009
- Author(s)
  森井孫俊, 酒井秀紀
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都府京都市
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-18390064
[Presentation] Function of KCC4 in the apical membrane of gastric parietal cells2009
- Author(s)
  Fujii T., Takahashi Y., Ikari A., Tabuchi Y., Morii M., Takeguchi N. and Sakai H.
- Organizer
  36th International Congress of Physiological Sciences(IUPS2009)
- Place of Presentation
  Kyoto
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-21390056
[Presentation] 胃プロトンポンプ阻害剤オメプラゾールとSCH28080は結合ポケットを共有する2009
- Author(s)
  森井孫俊
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都府京都市
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20056010
[Presentation] K^+-Cl^-cotransporter-4 associated with H^+, K^+-ATPase is involved in the mechanism of HCl secretion in the apical canalicular membrane of gastric parietal cells2009
- Author(s)
  Fujii T., Fujita K., Shimizu T., Takahashi Y., Tabuchi Y., Morii M., Takeguchi N. and Sakai H.
- Organizer
  Physiology of Anion Transportand Cell Volume Regulation(PAT-CVR 2009)
- Place of Presentation
  Okazaki
- Year and Date
  2009-08-05
- Data Source
  KAKENHI-PROJECT-21390056
[Presentation] Gastric proton pump activity is regulated by K^+-Cl^-cotransporter-4 in the apical canalicular membrane of parietal cells2009
- Author(s)
  Fujii T., Fujita K., Shimizu T., Takahashi Y., Tabuchi Y., Morii M., Takeguchi N. and Sakai H.
- Organizer
  JBS Biofrontier Symposium on Biochemistry of pH Homeostasis and Proton Circuit
- Place of Presentation
  Morioka
- Year and Date
  2009-07-24
- Data Source
  KAKENHI-PROJECT-21390056
[Presentation] 胃プロトンポンプ電荷移動路の分子動力学シミュレーション2008
- Author(s)
  森井孫俊
- Organizer
  日本薬学会第128年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-18390064
[Presentation] Involvement of the H_3O^+- Lys-164-Gln-161-Glu-345 charge transfer pathway in proton transport of gastric H^+,K^+-ATPase2008
- Author(s)
  Morii M, Yamauchi M, Ichikawa T, Fujii T, Takahashi Y, Asano S, Takeguchi N, Sakai H
- Organizer
  12th International ATPase Conference Na, K-ATPase and Related Transport ATPases of P-type : Structures, Mechanisms, and Roles in Health and Disease
- Place of Presentation
  Aarhus, Denmark
- Data Source
  KAKENHI-PROJECT-18390064
[Presentation] 胃プロトンポンプ電荷移動路の分子動力学シミュレーション2008
- Author(s)
  森井孫俊
- Organizer
  日本薬学会第128年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-18059012
[Presentation] Modulation of Gastric Proton Pump Activity by CLC-52008
- Author(s)
  Takahashi Y, Fujii T, Furuya H, Tabuchi Y, Ikari A, Sakamoto H, Naito I, Manabe K, Uchida S, Sasaki S, Asano S, Morii M, Takeguchi N, Sakai H
- Organizer
  Pan-Pacific International Partnership Conference on Pharmaceutical and Life Sciences (The 4th US-Japan Joint Conference)
- Place of Presentation
  Nagoya
- Year and Date
  2008-02-22
- Data Source
  KAKENHI-PROJECT-18390064
[Presentation] 胃プロトンポンプ電荷異動路の分子動力学シミュレーション2008
- Author(s)
  森井孫俊, 酒井秀紀
- Organizer
  日本薬学会第128年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-18390064
[Presentation] 胃プロトンポンプにおける電荷移動と水輸送のカップリング2007
- Author(s)
  森井孫俊, 酒井秀紀
- Organizer
  日本薬学会第127年会
- Place of Presentation
  富山県富山市
- Year and Date
  2007-03-29
- Data Source
  KAKENHI-PROJECT-18390064
[Presentation] Lumenal gating mechanism of gastric H^+,K^+-ATPase2006
- Author(s)
  Morii M, Sakai H
- Organizer
  20^<th> IUBMB International Congress of Biochemistry and Molecular Biology and 11^<th> FAOBMB Congress
- Place of Presentation
  Kyoto
- Year and Date
  2006-06-19
- Data Source
  KAKENHI-PROJECT-18390064
[Presentation] 胃プロトンポンプの分子動力学シミュレーション2006
- Author(s)
  森井孫俊, 酒井秀紀
- Organizer
  第28回生体膜と薬物との相互作用シンポジウム
- Place of Presentation
  第28回生体膜と薬物との相互作用シンポジウム
- Year and Date
  2006-11-09
- Data Source
  KAKENHI-PROJECT-18390064
[Presentation] Proton pathway of the gastric H^+,K^+-ATPase2006
- Author(s)
  Morii M, Sakai H
- Organizer
  Molecular Mechanism and Regulation in Cation Transport ATPases and Related Genetic Diseases
- Place of Presentation
  Kyoto
- Year and Date
  2006-06-16
- Data Source
  KAKENHI-PROJECT-18390064

1. SAKAI Hideki (60242509)

# of Collaborated Projects: 7 results

# of Collaborated Products: 19 results
2. ASANO Shinji (90167891)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. TABUCHI Yoshiaki (20322109)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. TAKEGUCHI Noriaki (00019126)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
5. TAKAHASHI Yuji (30422629)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
6. SHIMIZU Takahiro (40353437)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. FUJII Takuto (50567980)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. HATANAKA Yasumaru (30111181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MORII Magotoshi 森井 孫俊

森井 孫俊

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

[Journal Article] イオンポンプ研究の最前線2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Involvement of aquaporin-5 in differentiation of human gastric cancer cells2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Functional association between K^+-Cl^- cotransporter-4 and H^+,K^+-ATPase in the apical canalicular membrane of gastric parietal cells2009

Author(s)

Journal Title

Data Source

[Journal Article] Functional consequences of various leucine mutations in the M3/M4 loop of the Na^+,K^+-ATPase α-subunit2008

Author(s)

Journal Title

Data Source

[Journal Article] Involvement of the H_3O^+-Lys-164-G1n-161-Glu-345 charge transfer pathway in proton transport of gastric H^+, K^+-ATPase.2008

Author(s)

Journal Title

Data Source

[Journal Article] K^+-Cl^- cotransporter-3a up-regulates Na^+,K^+-ATPase in lipid rafts of gastric luminal parietal cells2008

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Involvement of the H_3O^+-Lys-164-Gln-161-Glu-345 charge transfer pathway in proton transport of gastric H^+, K^+-ATPase2008

Author(s)

Journal Title

Data Source

[Journal Article] Involvement of the H_3O^+-Lys-164-Gln-161-Glu-345 charge transfer pathway in proton transport of gastric H^+, K^+-ATPase.2008

Author(s)

Journal Title

Data Source

[Journal Article] Inhibition of P-type ATPases by [(dihydroindenyl)oxy]acetic acid (DIOA), a K^+-Cl^- cotransporter inhibitor2007

MORII Magotoshi 森井孫俊

森井孫俊