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Yoshida Koji  吉田 浩二

ORCIDConnect your ORCID iD *help
… Alternative Names

吉田 浩二  ヨシダ コウジ

YOSHIDA Koji  吉田 浩二

YOSIDA Koji  吉田 浩二

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Researcher Number 60230736
Other IDs
Affiliation (Current) 2025: 近畿大学, 生物理工学部, 教授
Affiliation (based on the past Project Information) *help 2018 – 2020: 近畿大学, 生物理工学部, 教授
2016: 近畿大学, 生物理工学部, 教授
2007 – 2013: Kinki University, Sch Med, Associate Professor
2001 – 2006: 近畿大学, 医学部, 講師
1998 – 1999: 近畿大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Basic Section 38030:Applied biochemistry-related / 膠原病・アレルギー・感染症内科学 / Orthopaedic surgery / Ophthalmology / Plastic surgery
Except Principal Investigator
Ophthalmology / Respiratory organ internal medicine / Functional biochemistry
Keywords
Principal Investigator
two-hybrid / 創傷治癒 / CTGF / fibronectin / 線維芽細胞 / 線維化 / fibrin / aggrecanase-1 / α1-antichymotrypsin / α1-antitrypsin … More / TGF-β / インテグリン / 臓器線維症 / 上皮細胞 / uPA / 角膜潰瘍 / 角膜線維芽細胞 / エピガロカテキンガレート / 上皮間葉転換 / transferrin / beta2-glycoprotein I / yeast two hybrid / α_1-antichymotrypsin / α_1-antitrypsin / two-hybrid法 / 酵母two-hybrid / aarecanase-1 / α2-antiplasmin / タンパク質 / shRNA / integrin / CIB1 / integrin α11 / transgelin … More
Except Principal Investigator
RPE / EMT / ARPE-19 / uPAR / uPA / Activation / Myofibroblast / Proteome / transforming growth factor / 繊維化 / 活性化 / プロテオーム / 筋線維芽細胞 / heme-regulatory motif / intracellular protein sorting / mitochondria / 5-aminolevulilate synthase / 5-アミノレブリン酸合成酵素 / ヘム調節モチーフ / タンパク質細胞内輸送 / ミトコンドリア / 5―アミノレブリン酸合成酵素 Less
  • Research Projects

    (8 results)
  • Research Products

    (38 results)
  • Co-Researchers

    (15 People)
  •  Basic research for organ fibrosis treatment using green tea catechin EGCGPrincipal Investigator

    • Principal Investigator
      Yoshida Koji
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 38030:Applied biochemistry-related
    • Research Institution
      Kindai University
  •  Investigation of uPA/uPAR induced EMT in ARPE-19

    • Principal Investigator
      AOMATSU Keiichi
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Ophthalmology
    • Research Institution
      Kindai University
  •  The role of the interaction between integrin and TGF-beta in the eye wound healingPrincipal Investigator

    • Principal Investigator
      YOSHIDA Koji
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Kinki University
  •  Roles of cytoskeletal proteins in organic fibrosis and their application of therapy in fibrotic diseasesPrincipal Investigator

    • Principal Investigator
      YOSHIDA Koji
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Kinki University
  •  Proteomic a-myofibroblastnalysis of activated- and inactivated

    • Principal Investigator
      MUNAKATA Hiroshi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Kinki University
  •  Research for the medical treatment of organic fibrosis by controlling the protein interacting with connective tissue growth factorPrincipal Investigator

    • Principal Investigator
      YOSHIDA Koji
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Kinki University
  •  Research for the medical treatment of rheumatoid arthritis by endogenous inhibitor of aggrecanasePrincipal Investigator

    • Principal Investigator
      YOSHIDA Koji
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kinki University
  •  Molecular Mechanism of Posttranscriptional modification by Heme

    • Principal Investigator
      MUNAKATA Hiroshi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      KINKI UNIVERSITY

All 2020 2019 2018 2014 2013 2012 2010 2008 2007 2006 2005 2004 Other

All Journal Article Presentation

  • [Journal Article] Glycosylated Bence Jones protein with poor thermal reactivity in heat coagulation tests2020

    • Author(s)
      Imoto M, Watanabe K, Yoshida K, Maeda Y, Nakae K, Kamisako T, Yamada T.
    • Journal Title

      Clin Lab 66:2365-2369,2020

      Volume: 66 Issue: 11/2020 Pages: 2365-2369

    • DOI

      10.7754/clin.lab.2020.200304

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07921, KAKENHI-PROJECT-18K05446
  • [Journal Article] Inhibition by Epigallocatechin Gallate of IL-1-Induced Urokinase-Type Plasminogen Activator Expression and Collagen Degradation by Corneal Fibroblasts2019

    • Author(s)
      Sugioka Koji、Yoshida Koji、Murakami Junko、Itahashi Motoki、Mishima Hiroshi、Nishida Teruo、Kusaka Shunji
    • Journal Title

      Investigative Opthalmology & Visual Science

      Volume: 60 Issue: 8 Pages: 2895-2903

    • DOI

      10.1167/iovs.19-27306

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K05446
  • [Journal Article] Interaction of calcium- and integrin-binding protein 1 with integrin α11 and its possible involvement in pulmonary fibrosis2014

    • Author(s)
      Yoshida K, Park AM, Ozaki S, Munakata H.
    • Journal Title

      Advances in Biological Chemistry

      Volume: 4 Issue: 01 Pages: 59-66

    • DOI

      10.4236/abc.2014.41009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592596
  • [Journal Article] Myofibroblasts: Biochemical and Proteomic Approaches to Fibrosis2013

    • Author(s)
      Honda E, Park AM, Yoshida K, Tabuchi M, Munakata H.
    • Journal Title

      Tohoku J. Exp. Med.

      Volume: 230 Issue: 2 Pages: 67-73

    • DOI

      10.1620/tjem.230.67

    • NAID

      10031182993

    • ISSN
      0040-8727, 1349-3329
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592596, KAKENHI-PROJECT-23700934
  • [Journal Article] Epigallocatechin-3-gallate suppresses transforming growth factor-βsignaling by interacting with the transforming growth factor-βtype II receptor2013

    • Author(s)
      Tabuchi M, Hayakawa S, Honda E, Ooshima K, Itoh T, Yoshida K, Park AM, Higashino H, Isemura M, Munakata H
    • Journal Title

      World J Exp Med

      Volume: 3 Issue: 4 Pages: 100-107

    • DOI

      10.5493/wjem.v3.i4.100

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592596, KAKENHI-PROJECT-23700934
  • [Journal Article] TGF-β_2 promotes RPE cell invasion into a collagen gel by mediating urokinase-type plasminogen activator (uPA) expression2013

    • Author(s)
      Sugioka K, Kodama A, Okada K, Iwata M, Yoshida K, Kusaka S, Matsumoto C, Kaji H, Shimomura Y
    • Journal Title

      Exp Eye Res

      Volume: 115 Pages: 13-21

    • DOI

      10.1016/j.exer.2013.06.020

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590268, KAKENHI-PROJECT-23592596, KAKENHI-PROJECT-23592597
  • [Journal Article] Immunohistochemical localization of urokinase-type plasminogen activator, urokinase-type plasminogen activator receptor and alpha2-antiplasmin in human corneal perforation: a case report2012

    • Author(s)
      杉岡 孝二
    • Journal Title

      BMC Ophthalmology

      Volume: 12 Issue: 1

    • DOI

      10.1186/1471-2415-12-60

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592596
  • [Journal Article] Conditioned media from lung cancer cell line A549 and PC9 inactivate pulmonary fibroblasts by regulating protein phosphorylation.2012

    • Author(s)
      Park AM, Hayakawa S, Honda E, Mine Y, Yoshida K, Munakata H.
    • Journal Title

      Arch Biochem Biophys.

      Volume: 15;518(2) Issue: 2 Pages: 133-41

    • DOI

      10.1016/j.abb.2011.12.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790772, KAKENHI-PROJECT-23592596
  • [Journal Article] Connective Tissue Growth Factor Cooperates with Fibronectin in Enhancing Attachment and Migration of Corneal Epithelial Cells2010

    • Author(s)
      Sugioka K, Yoshida K, Kodama A, Mishima H, Abe K, Munakata H, Shimomura Y.
    • Journal Title

      Tohoku J Exp Med. 222

      Pages: 45-50

    • NAID

      10027085615

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592111
  • [Journal Article] Transforming growth factor-β upregulates the expression of integrin and related proteins in MRC-5 human myofibroblasts2010

    • Author(s)
      Honda E, Yoshida K, Munakata H.
    • Journal Title

      Tohoku J Exp Med. 220

      Pages: 319-327

    • NAID

      10027084026

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592111
  • [Journal Article] Connective tissue growth factor binds to fibronectin through the type I repeat modules and enhances the affinity of fibronectin to fibrin.2007

    • Author(s)
      Yoshida K, Munakata H.
    • Journal Title

      Biochim Biophys Acta. 1770(4)

      Pages: 672-80

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590873
  • [Journal Article] Commective tissue growth factor binds to fibronectin through the type I repeat modules and enhances the affinity of fibronectin to fibrin2007

    • Author(s)
      Yoshida K
    • Journal Title

      Biochim Biophys Acta 1770

      Pages: 672-680

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590873
  • [Journal Article] Connective tissue growth factor binds to fibronectin through the type I repeatmodules and enhances the affinity of fibronectin to fibrin2007

    • Author(s)
      Yoshida K
    • Journal Title

      Biochim Biophys Acta 1770

      Pages: 672-680

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590873
  • [Journal Article] Connective tissue growth factor binds to fiboronectin through the type I repeat modules and enhances the affinity of fibornectin to fibrin :2006

    • Author(s)
      Yoshida, K.
    • Journal Title

      Biochim Biophys Acta 1770・4

      Pages: 627-680

    • Data Source
      KAKENHI-PROJECT-18590873
  • [Journal Article] Aggrecanase-1(ADAMTS-4) interacts with al-antitrypsin2005

    • Author(s)
      Koji Yoshida et al.
    • Journal Title

      Biochimica Biophysica Acta 1725・2

      Pages: 152-159

    • Data Source
      KAKENHI-PROJECT-16591000
  • [Journal Article] Conective tissue growth factor interacts with fibronectin2005

    • Author(s)
      Koji Yoshida et al.
    • Journal Title

      SEIKAGAKU 77・8

      Pages: 784-784

    • Data Source
      KAKENHI-PROJECT-16591000
  • [Journal Article] Aggrecanase-1 interacts with α_1-antitrypsin2004

    • Author(s)
      Koji Yoshida
    • Journal Title

      生化学 76・8

      Pages: 1030-1030

    • Data Source
      KAKENHI-PROJECT-16591000
  • [Journal Article] Connective tissue growth factor binds to fibronectin through the type I repeat. modules and enhances the affinity of fibronectin to fibrin

    • Author(s)
      Koji Yoshida, Hiroshi Munakata
    • Journal Title

      Biochim. Biophys. Acta (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591000
  • [Journal Article] Connective tissue growth factor binds to fibronectin through the type I repeat modules and enhances the affinity of fibronectin to fibrin

    • Author(s)
      Koji Yoshida, Hiroshi Munakata
    • Journal Title

      Biochim.Biophys.Acta (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591000
  • [Journal Article] Connective tissue growth factor binds to fibronectin through the type I repeat modules and enhances the affinity of fibronectin to fibrin

    • Author(s)
      Koji Yoshida, Hiroshi Munakata
    • Journal Title

      Biochim. Biophys. Acta (in press)

    • Data Source
      KAKENHI-PROJECT-16591000
  • [Presentation] 角膜線維芽細胞におけるIL-1誘導性u-PA発現およびコラーゲン分解に対するエピガロカテキンガレートの効果2020

    • Author(s)
      吉田 浩二 , 杉岡 孝二 , 髙橋 彩 , 村上 純子 , 三島 弘 , 西田 輝夫 , 日下 俊次
    • Organizer
      日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18K05446
  • [Presentation] ITGA11-fibronectinカスケードを介する癌関連肺線維芽細胞の遊走能の解析2019

    • Author(s)
      岩井萌, 十合晋作, 川路英哉, 伊藤昌可, Miniwan Tulafu, 渡邊純子, 門屋講太郎, 難波由喜子, 鈴木健司, 折茂 彰, 吉田浩二, 林崎良英, 高橋和久
    • Organizer
      第60回 日本肺癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K05446
  • [Presentation] HCEC+uPARにおけるTGF-β誘導性上皮間葉転換の検討2019

    • Author(s)
      木村優太 , 吉田浩二 , 坂田喜美 , 濱野将大
    • Organizer
      第92回 日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18K05446
  • [Presentation] 培養ヒト角膜上皮細胞におけるエピガロカテキンガレートの上皮間葉転換抑制効果および細胞毒性に関する検討2018

    • Author(s)
      濱野将大, 坂田喜美, 吉田浩二
    • Organizer
      日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18K05446
  • [Presentation] エピガロカテキンガレートが尿細管上皮細胞の上皮間葉転換に及ぼす効果2018

    • Author(s)
      坂田喜美、濱野将大、吉田浩二
    • Organizer
      日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18K05446
  • [Presentation] 培養尿細管上皮細胞におけるエピガロカテキンガレートによる上皮間葉転換抑制効果の検討2018

    • Author(s)
      坂田喜美、濱野将大、吉田浩二
    • Organizer
      日本結合組織学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K05446
  • [Presentation] HCEC+uPARにおける上皮間葉転換に対するEGCGの効果についての検討2018

    • Author(s)
      木村優太、吉田浩二
    • Organizer
      日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18K05446
  • [Presentation] 培養ヒト角膜上皮細胞におけるエピガロカテキンガレートによる上皮間葉転換抑制効果の検討2018

    • Author(s)
      濱野将大、坂田喜美、吉田浩二
    • Organizer
      日本結合組織学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K05446
  • [Presentation] マトリックスメタロプロテイナーゼ2はα_2-antiplasminを分解する2012

    • Author(s)
      吉田浩二
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡市
    • Year and Date
      2012-12-15
    • Data Source
      KAKENHI-PROJECT-23592596
  • [Presentation] インテグリンalpha11とcalcium and integrin binding protein 1の相互作用2010

    • Author(s)
      吉田浩二
    • Organizer
      第83回日本生化学会大会・第33回日本分子生物学会年会合同大会
    • Place of Presentation
      神戸市
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-20592111
  • [Presentation] インテグリンalpha11とcalcium and integrin binding protein 1の相互作用2010

    • Author(s)
      吉田浩二
    • Organizer
      第83回日本生化学会大会・第33回日本分子生物学会年会合同大会
    • Place of Presentation
      神戸ポートアイラン(神戸市)
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-20592111
  • [Presentation] transgelinノックダウンが肺線維芽細胞MRC-5に及ぼす効果2008

    • Author(s)
      吉田浩二
    • Organizer
      第31回日本分子生物学会合同年会・第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸市
    • Year and Date
      2008-12-10
    • Data Source
      KAKENHI-PROJECT-20592111
  • [Presentation] transgelin遺伝子ノックダウンが肺線維芽細胞MRC-5に及ぼす効果2008

    • Author(s)
      吉田浩二
    • Organizer
      第31回日本分子生物学会年会第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸市
    • Year and Date
      2008-12-10
    • Data Source
      KAKENHI-PROJECT-20592111
  • [Presentation] Connective tissue growth factor binds to fibronectin through the type I repeat modules and enhances the affinity of fibronectin to fibrin2007

    • Author(s)
      Koji Yoshida, Hiroshi Munakata
    • Organizer
      The 80th Annual Meeting of JBS The 30th Annual Meeting of MBSJ
    • Place of Presentation
      Yokohama
    • Year and Date
      2007-12-14
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590873
  • [Presentation] 結合組織成長因子はフィプロネクチンと結合し,フィプロネクチンのフィブリンへの親和性を増強する2007

    • Author(s)
      Yoshida K
    • Organizer
      第30回日本分子生物学会年会
    • Place of Presentation
      横浜市
    • Year and Date
      2007-12-14
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590873
  • [Presentation] 結合組織成長因子はフィプロネクチンと結合し、フィプロネクチンのフィブリンへの親和性を増強する2007

    • Author(s)
      Yoshida K
    • Organizer
      第30回日本分子生物学会年会
    • Place of Presentation
      横浜市
    • Year and Date
      2007-12-14
    • Data Source
      KAKENHI-PROJECT-18590873
  • [Presentation] TGF-beta2 promotes RPE cell invasion into collagen gel by mediating urokinase-type plasminogen activator (uPA) expression

    • Author(s)
      Sugioka K, Kodama A, Yoshida K, Okada K, Kusaka S, Matsumoto C, Shimomura Y.
    • Organizer
      ARVO 2013 Annual Meeting
    • Place of Presentation
      Seattle, USA
    • Data Source
      KAKENHI-PROJECT-23592596
  • [Presentation] マトリックスメタロプロテイナーゼ2はα2-antiplasminを分解する

    • Author(s)
      吉田 浩二
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡市
    • Data Source
      KAKENHI-PROJECT-23592596
  • 1.  SAITO Akio (40153788)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  HAGIHARA Satoru (40460852)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  SUGIOKA Koji (50399119)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 4.  MUNAKATA Hiroshi (90111294)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 5.  NAKATANI Tatsuya (40319661)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  HAYAKAWA Sumio (00368292)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  YAMAMOTO Kazuhiko (00166787)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  AMEMIYA Kana (30195929)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  FUKUDA Kanji (50201744)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  MATSUDA Toshirou (80411586)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  AOMATSU Keiichi (60411633)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  佐藤 真弓 (90388512)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  PARK Ah-mee
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  岡田 清孝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  山田 俊幸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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