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Uetsuka Koji  上塚 浩司

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UETSUKA Koji  上塚 浩司

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Researcher Number 60251419
Other IDs
Affiliation (Current) 2025: 茨城大学, 応用生物学野, 教授
Affiliation (based on the past Project Information) *help 2007: The University of Tokyo, Chief scientist
2007: 東京大学, 日本生物化学研究所, 研究員
2005 – 2006: 東京大学, 大学院農学生命科学研究科, 助手
2002 – 2005: 東京大学, 大学院・農学生命科学研究科, 助手
2000: GRADUATE SCHOOL OF AGRICUTURAL AND LIFE SCIENCES, THE UNIVERSITY OF TOKYO ASSISTANT PROFESSOR, 大学院・農学生命科学研究科, 助手 … More
2000: 東京大学, 大学院・農学生命科学研究科, 教授
1999: 東大, 農学生命科学研究科, 助手
1996 – 1998: 東京大学, 大学院・農学生命科学研究科, 助手
1997: 東京大学, 大学院農学生命科学研究科, 助手
1994 – 1995: 東京大学, 農学部, 助手 Less
Review Section/Research Field
Principal Investigator
Applied veterinary science / Applied veterinary science
Except Principal Investigator
Applied veterinary science / Basic veterinary science/Basic zootechnical science / Clinical veterinary science / Applied veterinary science / Basic veterinary science/Basic zootechnical science
Keywords
Principal Investigator
CYP / environmental chemicals / p53 gene / neural progenitor cell / apoptosis / cell cycle / placental toxicity / fetal toxicity / CYP inducers / Ara-C … More / マイクロアレイ解析 / 胎児中枢神経傷害 / Ethylnitrosourea / 胎児脳 / 妊娠動物 / 胎児肝臓 / 母体肝臓 / 胎盤 / T-2toxin / CYP inducer / 5AzC / p53 / etoposide / hydroxyurea / 5-azacytidine / 胎児中枢神経障害 / 環境化学物質 / p53遺伝子 / 神経前駆細胞 / アポトーシス / 細胞周期 / 胎盤毒性 / 胎児毒性 / 分化 / ガラクトサミン / 肝 / 細胞外基質 / ミニラット / oval cell / ラット / 肝腎毒性 / 高トリグリセリド血症 / アセトアミノフェン … More
Except Principal Investigator
老化 / MPTP / Microarray / Brain / マイクロアレイ / 脳 / APP / Environmental chemicals / Aging / DNA methylation / Apoptosis / DNAメチル化 / アポトーシス / 環境化学物質 / 紫外線 / ヘアレスラット / ヘアレス犬 / Prion model / Beta amyloid(A beta) / Nprilysin / Cat / Dog / 猫 / 犬 / 神経幹細胞アポトーシス / BSEモデル / パーキンソン病モデル / ウシ / マウス / プリオンモデル / βアミロイド / ネプリライシン / ネコ / イヌ / zearalenon / Feed contamination / Farm animals / Thai / aflatoxin / カビ毒 / タイ国 / ブタ / 飼料 / 毒性 / かび毒 / ゼアラレノン / 飼料汚染 / 家畜 / タイ / アフラトキシン / DNA methyltransferase / Dimethyl Sulfoxide / ES cell / Adipogenesis / Epigenetics / パイロシークエンス法 / 脂肪細胞 / 肝臓 / Dnmt / エピジェネティックス / DNAメチル基転移酵素 / ジメチルスルホキシド / ES細胞 / 脂肪細胞分化 / エピジェネティクス / Senile plaques / Mammals / Computer / Amyloid beta / 老人班 / 老人斑 / 動物 / コンピューター / アミロイドβ / Hairless rats / Hairless dogs / Skin injury / Ultraviolet light / Maneb / H_2O_2 / Ultraviolet / Hairless dog / Environmental Chemical / Skin response / Haieless dog / UV irradiation / contact dermatitis / picryl chloride / Jic mouse / IQI / basal cell apoptosis / T-2 toxin / ILA-Ht rat / WBN / 皮膚障害 / Dementia / Development / Ribosomal protein L4 (rpL4) / PC12 cells / 5-Azacytidine / 神経細胞 / 痴呆 / 発生 / リボソームタンパクL4(rpL4) / PC12細胞 / 5-アザシチジン / 皮膚反応 / 網膜 / Maf / ニワトリ / ヌードマウス / SCIDマウス / マウス肝炎 / B型肝炎 / C型肝炎 / ウイルス Less
  • Research Projects

    (12 results)
  • Research Products

    (18 results)
  • Co-Researchers

    (17 People)
  •  Comparative studies on beta amyloid deposition and brain aging

    • Principal Investigator
      NAKAYAMA Hiroyuki
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Clinical veterinary science
    • Research Institution
      The University of Tokyo
  •  Multilateral study on the fetal toxicity with regard to the maternal-placental-fetal axisPrincipal Investigator

    • Principal Investigator
      UETSUKA Koji, 土井 邦雄
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied veterinary science
    • Research Institution
      The University of Tokyo
  •  DNA Methylation Analyses in Pathology

    • Principal Investigator
      SHIOTANI Kunio
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Basic veterinary science/Basic zootechnical science
    • Research Institution
      The University of Tokyo
  •  The study of the effect of natural contamination of feed with mycotoxins on the occurrence of diseases in farm animals.

    • Principal Investigator
      KUMAGAI Susumu
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied veterinary science
    • Research Institution
      The University of Tokyo
  •  Comparative evolutionary studies on the expmssion of dementia-related genes in aging nonhuman animals

    • Principal Investigator
      NAKAYAMA Hiroyuki
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied veterinary science
    • Research Institution
      The University of Tokyo
  •  oval cellの増殖・分化と細胞外基質に関する基礎的研究Principal Investigator

    • Principal Investigator
      上塚 浩司
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Applied veterinary science
    • Research Institution
      The University of Tokyo
  •  ANALYSIS OF CHARACTERISTICS AND PATHOGENESIS OF SKIN INJURY INDUCED BY ENVIRONMENTAL CHEMICALS AND ULTRAVIOLET LIGHT

    • Principal Investigator
      DOI Kunio
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Applied veterinary science
    • Research Institution
      THE UNIVERSITY OF TOKYO
  •  環境化学物質の皮膚刺激性ならびに紫外線との複合作用に関する基礎的研究

    • Principal Investigator
      土井 邦雄
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Applied veterinary science
    • Research Institution
      The University of Tokyo
  •  Mechanism of apoptosis and DNA methylation during development and aging of neuronal cells

    • Principal Investigator
      NAKAYAMA Hiroyuki
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Basic veterinary science/Basic zootechnical science
    • Research Institution
      The University of Tokyo
  •  病態動物における薬物の毒性発現様式の修飾機構に関する基礎的研究Principal Investigator

    • Principal Investigator
      上塚 浩司
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Applied veterinary science
    • Research Institution
      The University of Tokyo
  •  癌原遺伝子C-maf産物タンパク質のニワトリ網膜における発現とその機能

    • Principal Investigator
      中山 裕之
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Basic veterinary science/Basic zootechnical science
    • Research Institution
      The University of Tokyo
  •  人の各型慢性肝炎に対応する動物ウイルス肝炎モデルの開発と応用

    • Principal Investigator
      後藤 直彰
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Applied veterinary science
    • Research Institution
      The University of Tokyo

All 2008 2006 2005

All Journal Article Presentation

  • [Journal Article] Complementary distributions of amyloid-beta and neprilysin in the brains of dogs and cats.2008

    • Author(s)
      Takeuchi, Y, Uetsuka, K, Murayama, M., Kikuta, F., Takashima, A., Doi, K., and Nakayama, H.
    • Journal Title

      Vet. Pathol. 45(印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17380185
  • [Journal Article] Neurotoxicity of MPTP to migrating neuroblasts: Studies・in acute and subacute mouse models of Parkinson's disease.2008

    • Author(s)
      He, X. J., Yamauchi, H., Uetsuka, K., and Nakayama, H.
    • Journal Title

      Neurotoxicol. 29(印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17380185
  • [Journal Article] Neurotoxicity of MPTP to migrating neuroblasts : Studies in acute and subacute mouse models of Parkinson''s disease2008

    • Author(s)
      He, X. J., Yamauchi, H., Uetsuka, K., Nakayama, H.
    • Journal Title

      Neurotoxicol 29

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17380185
  • [Journal Article] Incorporation of β -amyloid protein through the bovine ileal epithelium before and after weatning:a model for orally transmitted amyloidoses2008

    • Author(s)
      Yasuhisa Ano, Hiroyuki Nakayama, Yusuke Sakai, Akikazu Sakudo, Maiko Endo, Shogo Ebisu, Jun YouLi, Koji Uetsuka, Noboru Manabe and Takashi Onodera
    • Journal Title

      Microbiology and Immunology (査読中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17380185
  • [Journal Article] Neural progenitor cells are protected against MPTP by MAO-B inbititors2008

    • Author(s)
      He. X. J., Uetsuka, K., Nakayama, H.
    • Journal Title

      submitted to Neurotoxicol

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17380185
  • [Journal Article] Intracranial meningioma with polygonal granular cell appearance in a Chihuahua.2008

    • Author(s)
      Takeuchi, Y., Ohnishi Y., Matsunaga, S., Nakayama, H., and Uetsuka, K.
    • Journal Title

      J.Vet. Med. Sci. 70(印刷中)

    • NAID

      110006688964

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17380185
  • [Journal Article] Intracranial meningioma with polygonal granular cell appearance in a Chihuahua2008

    • Author(s)
      Takeuchi, Y., Ohnishi Y., Matsunaga, S., Nakayama, H., Uetsuka, K.
    • Journal Title

      J. Vet. Med. Sci. 70

    • NAID

      110006688964

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17380185
  • [Journal Article] Complemenatry distributions of amyloid-beta and neprilysin in the brains of dogs and cats2008

    • Author(s)
      Yoshinori Takeuchi, Koji Uetsuka, Miyuki Murayama, Akihiko Takashima, Kunio Doi and Hkouki Nakayama
    • Journal Title

      Veterinary Pathology 45(掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17380185
  • [Journal Article] Complementary distributions of amylod-beta and neprilysin in the brains of dogs and cats2008

    • Author(s)
      Takeuchi, Y., Uetsuka, K., Murayama, M., Kikuta, F., Takashima, A., Doi, K., Nakayama, H.
    • Journal Title

      Vet. Pathol 45

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17380185
  • [Journal Article] Neural progenitor cells are protected against MPTP by MAO-B inhibitors.2008

    • Author(s)
      He, X. J., Uetsuka, K., and Nakayama, H.
    • Journal Title

      Neurotoxicol. 29(投稿中)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17380185
  • [Journal Article] Histopathological changes in the brain of mouse fetuses by etoposide-administration.2006

    • Author(s)
      Nam C., Woo G.H., Uetsuka K., Nakayama H., Doi K.
    • Journal Title

      Histology and Histopathology 21

      Pages: 257-263

    • NAID

      130007003554

    • Data Source
      KAKENHI-PROJECT-16380206
  • [Journal Article] Microarray analysis of T-2 toxin-induced liver, placenta and fetal liver lesions in pregnant nats.2005

    • Author(s)
      Sehata S., Kiyosawa N., Atsumi F., Ito K., Yamoto T., Teranishi M., Uetsuka K., Nakayama H., Doi K.
    • Journal Title

      Exp.Toxicol.Pathol., 57

      Pages: 15-28

    • Data Source
      KAKENHI-PROJECT-16380206
  • [Journal Article] Two cases of feline malignant craniophalingioma.2005

    • Author(s)
      Nagata, T., Nakayama, H., Uchida, K., Uetsuka, K., Yasoshima, A., Yasunaga, S., Masuda, K., Tsujimoto, H., Kuwajima, E., Nishimura, R., Sassaki, N. and Doi, K.
    • Journal Title

      Vet. Pathol. 42

      Pages: 663-665

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17380185
  • [Journal Article] Two cases of feline malignant cranipophalingioma2005

    • Author(s)
      Nagata, T., Nakayama, H., Uchida, K., Uetsuka, K., Yasoshima, A., Yasunaga, S., Masuda, K., Tsujimoto, H., Kuwajima, E., Nishimura, R., Sassaki, N. Doi, K.
    • Journal Title

      Vet. Pathol 42

      Pages: 663-665

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17380185
  • [Presentation] MPTP誘発神経前駆細胞アポトーシスーMPTP誘発パーキンソン病のマウスモデルにおける新知見2006

    • Author(s)
      何希君, 中山裕之, 山内啓司, 上塚浩司, 土井邦雄
    • Organizer
      第33回日本トキシコロジー学会
    • Place of Presentation
      名古屋市
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17380185
  • [Presentation] MPTP-derived apoptosis in neural precursor cells -A new observation in the MPTP-induced Parkinson model in mice2006

    • Author(s)
      He, X. J., Nakayama, H., Yamauchi, H., Uetsuka K., Doi K.
    • Organizer
      33th Meeting of the Japanese Society of Toxicology
    • Place of Presentation
      Naogya
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17380185
  • [Presentation] イヌとネコの大脳におけるNeprilysin活性の比較2005

    • Author(s)
      竹内由則, 中山裕之, 上塚浩司, 土井邦雄
    • Organizer
      第140回日本獣医学会
    • Place of Presentation
      鹿児島市
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17380185
  • [Presentation] Activities of Neprilysin in the brain of dogs and cats2005

    • Author(s)
      Takeuch, Y., Nakayama, H., Uetsuka, K., Doi, K.
    • Organizer
      140th Meeting of the Japanese Society of Veterinary Sciences
    • Place of Presentation
      Kagoshima
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17380185
  • 1.  NAKAYAMA Hiroyuki (40155891)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 18 results
  • 2.  DOI Kunio (70155612)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 2 results
  • 3.  SHIOTANI Kunio (80196352)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  KUMAGAI Susumu (60109965)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  NISHIHARA Masugi (90145673)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  ONO Ken-ichiro (50111480)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  KARAKI Hideaki (60011912)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  YOSHIKAWA Yasuhiro (80109975)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  TAKAHASHI Shinichiro (00197146)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  TANAKA Satoshi (90242164)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  KONISHI Yoshiko (10195761)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  ONODERA Takashi (90012781)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  MANABE Noboru (80243070)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 14.  UCHIDA Kazuyuki (10223554)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 15.  後藤 直彰 (70011989)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  西澤 誠 (30192248)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  板垣 慎一 (00159823)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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