Utsunomiya Hirotoshi 宇都宮洋才

… Alternative Names

HIROTOSHI Utsunomiya 宇都宮洋才

UTSUNOMIYA Hirotosi 宇都宮洋才

宇都宮洋才ウツノミヤヒロトシ

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Researcher Number	60264876
Affiliation (Current)	2025: 大阪河崎リハビリテーション大学, リハビリテーション学部, 教授
Affiliation (based on the past Project Information) *help	2015 – 2018: 和歌山県立医科大学, 共同利用施設, 准教授 2015: 和歌山県立医科大学, 中央共通機器室, 准教授 2015: 和歌山県立医科大学, 中央機器室, 准教授 2013 – 2015: 和歌山県立医科大学, 公私立大学の部局等, 准教授 2014: 和歌山県立医科大学, 中央機器施設, 准教授 … More 2013: 和歌山県立医科大学, 准教授 2010 – 2013: 和歌山県立医科大学, 医学部, 准教授 2011 – 2012: 和歌山県立医科大学, 中央機器施設, 准教授 2009: 和歌山県立医科大学, 中央機器室, 講師 2002 – 2009: 和歌山県立医科大学, 医学部, 講師 2007: Wakayama Medical University, Medical Department, Professor 1998 – 2000: 和歌山県立医科大学, 医学部, 講師 1994: 和歌山県立医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Eating habits, studies on eating habits Except Principal Investigator Obstetrics and gynecology / Digestive surgery / Human pathology / Applied health science / Epidemiology and preventive medicine / Eating habits / Public health/Health science / Experimental pathology / General surgery … More / Applied health science / Rehabilitation science/Welfare engineering / Environmental physiology (including Physical medicine and Nutritional physiology) / Eating habits, studies on eating habits / Bacteriology (including Mycology) Less
Keywords	Principal Investigator 分子標的治療 / Nrf2 / 転写因子 / 機能性食品 / 肝発癌 / 脂肪性肝炎 / 生活習慣病 Except Principal Investigator 転写因子 / 肥満 / 抗癌剤 … More / 脂肪性肝炎 / GnRH agonist / アポトーシス / CPT-11 / oncogene / breast cancer / 代謝機能 / 骨格筋 / 肥満関連肝疾患 / 自然免疫 / 脂肪性肝疾患 / 胆道癌 / apoptosis / Anticancer drug / 卵巣癌 / ALS / parathyroid / endocrine / neoplasms / menin / 腫瘍マーカー / pathology / 乳癌 / VCAM-1 / 腸内細菌叢 / 肥満性肝疾患 / 糖鎖医学 / バイオマーカー / レクチン / 子宮癌 / 運動機能 / DAP kinase / 生活習慣病 / Nrf2 / 酸化ストレス / 分子標的治療 / 糖鎖 / 顆粒膜細胞 / 胆嚢癌 / 消化器疾患 / 腸内細菌 / 梅 / 臨床試験 / 術前 / WFA / マーカー / 診断 / 胆管癌 / ３T3-L1細胞 / 脂肪前駆細胞 / 香酸柑橘 / 脂肪分解活性 / 3T3-L1細胞 / ポリメトキシフラボノイド / 抗肥満効果 / ジャバラ / drug resistance / ovarian cancer / 抗癌剤耐性 / Granulosa cell / GnRHagonist / Drug resistance / Ovarian cancer / Uterine cancer / 薬剤耐性 / regeneration medicine / endometriosis / cytokine / embryo implantation / endometrium / 再生医療 / 子宮内膜症 / サイトカイン / 着床 / 子宮内膜 / spinal snondylotic myelopathy / occpation / Kii ALS / focus ALS / suryival rate / trace metals / risk facters / 発症頻度 / 筋萎縮生側索硬化症 / 環境要因 / 発症関連要因 / QOL / PTH / Ca / 多発地 / 多発地ALS / 累積生存率 / 微量元素 / 危険因子 / 予後関連因子 / 筋萎縮性側索硬化症 / chromosome / loss of heterozygosity / point mutation / retinoic acid receptor β2 / 染色体 / ヘテロ接合体消失(LOH) / 点突然変異 / レチノイン酸受容体β2 / prathyroid / vitamin D receptor / calcitonin receptor / prostatic specific antigen / androgen receptor / estrogen receptor / breast conserving surgery / prognositic factor / estrogen-like substance / 免疫組織化学 / 予後因子 / epidemiology / prognostic factor / ビタミンD受容体 / カルシトニン受容体 / 前立腺特異抗原 / アンドロゲン受容体 / エストロゲン受容体 / 病理 / Integrin / Bone metastasis / インテグリン / 骨転移 / 動物モデル / 肝発癌 / NASH / 過食肥満マウス / Kupffer細胞 / リポ多糖 / 遺伝子改変マウス / 非アルコール性脂肪性肝炎 / 身体機能 / 高齢肥満者 / 異所性脂肪 / 加速度訓練 / 脂肪酸代謝 / 骨格筋代謝 / 肝代謝 / 胆道癌モデル / 肝内胆管癌 / 糖蛋白質 / 糖鎖構造解析 / 分子標的療法 / 卵巣機能不全 / 機能性食品 / 標的治療 / 糖転移酵素 / 糖鎖分子 / 悪性挙動 / death-associated protein kinase / 予防 / 卵巣機能障害 / 抗がん剤 / PCR法 / 感染実験 / 人畜共通感染症 / in situ hybridization法 / Real-time PCR法 / 酵素抗体法 / ホルマリン固定パラフィン切片 / 皮膚生検 / 病理診断 / 早期診断 / 日本紅斑熱 / 癌疫学 / 活性酸素 / 重金属 / 疫学 / 化学発癌 / 比較ゲノミックハイブリダイゼーション / フィブロネクチン / TSH受容体 / gene trapping / 甲状腺癌未分化転化 / oncofetal fibronectin / Comparative genomic hybridization / 甲状腺乳頭癌培養細胞株 Less

Improvement effect of Japanese apricot (Prunus mume Siebold et Zucc; Ume) on lower intestinal microflora.
- Principal Investigator
  
  MAEKITA TAKAO
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Epidemiology and preventive medicine
- Research Institution
  Wakayama Medical University
Antiobesity compounds from Citrus jabara and there mode of action
- Principal Investigator
  
  Okuno Yoshiharu
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Wakayama National College of Technology
Development of high sensitivity diagnostic system for intrahepatic cholangiocarcinoma using glycoprotein molecular marker
- Principal Investigator
  
  Higuchi Ryota
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Women's Medical University
加速度訓練による高齢肥満者の身体機能および代謝病態の改善, 脂肪性肝疾患の進展予防
- Principal Investigator
  
  江口清
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  University of Tsukuba
Development of overeating-induced obese mouse assuming human life style-related diseases and investigation of pathophysiological factors associated with NASH
- Principal Investigator
  
  Mizogami Yuji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  University of Tsukuba
Nrf2 activation inhibits steatohepatitis and liver cancer in overeating-induced obese mice.
- Principal Investigator
  
  Ariizumi Syunnichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Tokyo Women's Medical University
Development of glycoprotein-biomrkers for biliary tract cancers and establishment of novel diagnostic system using the combination of these biomarkers
- Principal Investigator
  
  YAMAMOTO Masakazu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Women's Medical University
Exercise inhibits progression of obesity-related fatty liver disease through the regulation of activated innate immunity
- Principal Investigator
  
  TOGASHI Shinji
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied health science
- Research Institution
  University of Tsukuba
Iprovement of metabolic and exercise function of skeletal muscles through activation of transcription factor, and prevention of obesity-related liver disease
- Principal Investigator
  
  ISHIGE Kazunori
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  University of Tsukuba
Improvement of metabolic and exercise function of skeletal muscles through activation of transcription factor, and prevention of obesity-related liver disease
- Principal Investigator
  
  SHODA Junichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  University of Tsukuba
DAPキナーゼを対象とする婦人科悪性腫瘍に対する新分子標的治療法の開発
- Principal Investigator
  
  田中哲二
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Wakayama Medical University
Activation of transcription factor by functional food constituents inhibits the onset and progression of obesity-related liver diseases through attenuating the enhanced innate immunity levels.
- Principal Investigator
  
  TAKAHASHI Hiroshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  University of Tsukuba
抗癌剤による卵巣機能不全の分子機構解明と予防方法の確立
- Principal Investigator
  
  宇都宮智子
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Wakayama Medical University
Novel prevention of development of life style-related liver diseases and liver carcinogenesis through an activation of transcription factor induced by functional foodsPrincipal Investigator
- Principal Investigator
  
  UTSUNOMIYA Hirotoshi, 中原朗
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  Wakayama Medical University
  University of Tsukuba
胆道癌の悪性挙動(浸潤・転移)を制御する糖鎖分子の探索と新規分子標的治療への応用
- Principal Investigator
  
  遠藤隆志
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  University of Tsukuba
Rapid diagnosis of Japanese spotted fever by immunohistochemistry and pathophysiological significance of the rickettsiosis as zoonosis
- Principal Investigator
  
  MAHARA Fumihiko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Fujita Health University
PREVENTIVE ENDOCRINE THERAPY FOR ANTICANCER DRUG-INDUCED OVARIAN FAILURE
- Principal Investigator
  
  UTSUNOMIYA Tomoko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Wakayama Medical University
化学発癌が疑われるインドの胆嚢癌の発生機序の解明と早期診断に関する国際共同研究
- Principal Investigator
  
  小田高司
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nagoya University
Molecular targets and specific preventive therapy of anticancer drug-induced ovarian failure
- Principal Investigator
  
  MINAMI Sawako
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Wakayama Medical University
Identification and clinical application of novel antiapoptotic factor produced from ovarian cancer cells
- Principal Investigator
  
  TANAKA Tetsuji, 粉川克司
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Wakayama Medical University
Mechanisms of postmenstrual endometrial remodeling and intercellular signalings during embryo implantation
- Principal Investigator
  
  UMESAKI Naohiko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Wakayama Medical University
Molecular targeting therapy for anticancer drug-resistant cancer cells derived from uterus and ovary
- Principal Investigator
  
  TANAKA Tetsuji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Wakayama Medical University
Epidemiological study on ALS in Wakayama Prefecture special reference to the incidence, risk factors and QOL of patients
- Principal Investigator
  
  KIHIRA Tameko
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Public health/Health science
- Research Institution
  Wakayama Medical University
Bilallelic inactivation of retinoic acid receptor β2 gene by epigenetic change in breast cancer
- Principal Investigator
  
  KAKUDO Kennichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Wakayama Medical University
Analysis of menin gene in human neoplasms.
- Principal Investigator
  
  KAKUDO Kennichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Wakayama Medical University
International collaboration study on breast cancer
- Principal Investigator
  
  KAKUDO Kennichi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Human pathology
- Research Institution
  Wakayama Medical University
体細胞genetrap法を用いた甲状腺癌悪性転化の機序解析とその制御
- Principal Investigator
  
  NAKAMAURA Yasushi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Wakayama Medical University
Study on the role of integrin alpha4beta1 in bone metastasis
- Principal Investigator
  
  MATSUURA Nariaki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Osaka University
  Wakayama Medical University

All 2018 2016 2013 2012 2011 2010 2009 2008 2007 2006 2005

All Journal Article Presentation

[Journal Article] Deletion of Nrf2 leads to rapid progression of steatohepatitis in mice fed atherogenic plus high-fat diet2013
- Author(s)
  Okada K, Warabi E, Sugimoto H, Horie M, Gotoh N, Tokushige K, Hashimoto E, Utsunomiya H, Takahashi H, Ishii T, Yamamoto M, Shoda J
- Journal Title
  
  J Gastroenterol
  
  Volume: 48 Pages: 620-32
- NAID
  10031177013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24650436
[Journal Article] Deletion of Nrf2 leads to rapid progression of steatohepatitis in mice fed atherogenic plus high-fat diet2013
- Author(s)
  Okada K, Warabi E, Sugimoto H, Horie M, Gotoh N, Tokushige K, Hashimoto E, Utsunomiya H, Takahashi H, Ishii T, Yamamoto M, Shoda J
- Journal Title
  
  J Gastroenterol
  
  Volume: 48 Pages: 620-32
- NAID
  10031177013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300250
[Journal Article] Deletion of Nrf2 leads to rapid progression of steatohepatitis in mice fed atherogenic plus high-fat diet2013
- Author(s)
  Okada K, Warabi E, Sugimoto H, Horie M, Gotoh N, Tokushige K, Hashimoto E, Utsunomiya H, Takahashi H, Ishii T, Yamamoto M, Shoda J
- Journal Title
  
  J Gastroenterol
  
  Volume: 48 Pages: 620-632
- NAID
  10031177013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282172
[Journal Article] Deletion of Nrf2 leads to rapid progression of steatohepatitis in mice fed atherogenic plus high-fat diet2013
- Author(s)
  27. Okada K, Warabi E, Sugimoto H, Horie M, Gotoh N, Tokushige K, Hashimoto E, Utsunomiya H, Takahashi H, Ishii T, Yamamoto M, Shoda J
- Journal Title
  
  J Gastroenterol
  
  Volume: 48 Pages: 620-632
- NAID
  10031177013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24650436
[Journal Article] Deletion of Nrf2 leads to rapid progression of steatohepatitis in mice fed atherogenic plus high-fat diet2013
- Author(s)
  Okada K, Warabi E, Sugimoto H, Horie M, Gotoh N, Tokushige K, Hashimoto E, Utsunomiya H, Takahashi H, Ishii T, Yamamoto M, Shoda J
- Journal Title
  
  J Gastroenterol
  
  Volume: 48 Pages: 620-632
- NAID
  10031177013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390323
[Journal Article] Deletion of Nrf2 leads to rapid progression of steatohepatitis in mice fed atherogenic plus high-fat diet2013
- Author(s)
  Okada K, Warabi E, Sugimoto H, Horie M, Gotoh N, Tokushige K, Hashimoto E, Utsunomiya H, Takahashi H, Ishii T, Yamamoto M, Shoda J
- Journal Title
  
  J Gastroenterol
  
  Volume: 48 Pages: 620-32
- NAID
  10031177013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282212
[Journal Article] Deletion of Nrf2 leads to rapid progression of steatohepatitis in mice fed atherogenic plus high-fat diet2013
- Author(s)
  Okada K, Warabi E, Sugimoto H, Horie M, Gotoh N, Tokushige K, Hashimoto E, Utsunomiya H, Takahashi H, Ishii T, Yamamoto M, Shoda J
- Journal Title
  
  J Gastroenterol
  
  Volume: 48 Pages: 620-32
- NAID
  10031177013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659104
[Journal Article] Nrf2 inhibits hepatic iron accumulation and counteracts oxidative stress-induced liver injury in nutritional steatohepatitis2012
- Author(s)
  Okada K, Warabi E, Sugimoto H, Horie M, Tokushige K, Ueda T, Harada N, Taguchi K, Hashimoto E, Itoh K, Ishii T, Utsunomiya H, Yamamoto M, Shoda J
- Journal Title
  
  J Gastroenterol
  
  Volume: 47 Pages: 942-35
- NAID
  10031051379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300250
[Journal Article] Nrf2 inhibits hepatic iron accumulation and counteracts oxidative stress-induced liver injury in nutritional steatohepatitis.2012
- Author(s)
  Okada K, Warabi E, Sugimoto H, Horie M,Tokushige K, Ueda T,Harada N, Taguchi K, Hashimoto E, Itoh K, Ishii T,Utsunomiya H, Yamamoto M, Shoda J
- Journal Title
  
  J Gastroenterol
  
  Volume: 47 Pages: 924-35
- NAID
  10031051379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300260
[Journal Article] Nrf2 inhibits hepatic iron accumulation and counteracts oxidative stress-induced liver injury in nutritional steatohepatitis2012
- Author(s)
  Okada K, Warabi E, Sugimoto H, Horie M, Tokushige K, Ueda T, Harada N, Taguchi K, Hashimoto E, Itoh K, Ishii T, Utsunomiya H, Yamamoto M, Shoda J
- Journal Title
  
  J Gastroenterol
  
  Volume: 47 Pages: 924-35
- NAID
  10031051379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659104
[Journal Article] Deletion of Nrf2leads to rapid progression of steatohepatitis in mice fed atherogenic plus high-fat diet2012
- Author(s)
  Okada K, Warabi E, Sugimoto H, Horie M,Gotoh N, Tokushige K, Hashimoto E,Utsunomiya H, Takahashi H,Ishii T,Yamamoto M, Shoda J
- Journal Title
  
  J Gastroenterol
  
  Volume: 48 Issue: 5 Pages: 620-632
- DOI
  10.1007/s00535-012-0659-z
- NAID
  10031177013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300260, KAKENHI-PROJECT-23300250, KAKENHI-PROJECT-23660033, KAKENHI-PROJECT-24390488, KAKENHI-PROJECT-24650436, KAKENHI-PROJECT-24659104
[Journal Article] Nrf2 inhibits hepatic iron accumulation and counteracts oxidative stress-induced liver injury in nutritional steatohepatitis2012
- Author(s)
  Okada K, Warabi E, Sugimoto H, Horie M, Tokushige K, Ueda T, Harada N, Taguchi K, Hashimoto E, Itoh K, Ishii T, Utsunomiya H, Yamamoto M, Shoda J
- Journal Title
  
  J Gastroenterol
  
  Volume: 47 Pages: 924-35
- NAID
  10031051379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24650436
[Journal Article] Nrf2 inhibits hepatic iron accumulation and counteracts oxidative stress-induced liver injury in nutritional steatohepatitis2012
- Author(s)
  Okada K, Warabi E, Sugimoto H, Horie M, Tokushige K, Ueda T, Harada N, Taguchi K, Hashimoto E, Itoh K, Ishii T, Utsunomiya H, Yamamoto M, Shoda J
- Journal Title
  
  J Gastroenterol
  
  Volume: (In press)
- NAID
  10031051379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300275
[Journal Article] 抗癌剤CPT-11誘発マウス卵巣機能障害に対するGnRH agonistの予防機序2011
- Author(s)
  宇都宮智子, 田中哲二, 宇都宮洋才
- Journal Title
  
  日本受精着床学会雑誌
  
  Volume: 28 Pages: 31-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591863
[Journal Article] 梅肉エキスとがん予防2011
- Author(s)
  宇都宮洋才、稲田健一
- Journal Title
  
  Functional food
  
  Volume: 14 Pages: 368-373
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300275
[Journal Article] 挙児希望の子宮内膜癌または1C期以上卵巣癌患者に対する子宮卵巣温存療法2011
- Author(s)
  田中哲二、宇都宮智子, ほか
- Journal Title
  
  日本受精着床学会雑誌
  
  Volume: 28 Pages: 135-138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591863
[Journal Article] Co-operative thermal inactivation of herpes simplex virus and influenza virus by arginine and NaCl2009
- Author(s)
  Utsunomiya H, Ichinose M, Tsujimoto K, Katsuyama Y, Yamasaki H, Koyama AH, Ejima D, Arakawa T
- Journal Title
  
  Int J Pharm
  
  Volume: 21(366) Pages: 99-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300275
[Journal Article] Direct effects of CPT-11 and SN38 on ovarian granulosa cells.2009
- Author(s)
  Utsunomiya T, Tanaka T, Utsunomiya H, Umesaki N.
- Journal Title
  
  Molecular Medicine Reports 2
  
  Pages: 189-192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591906
[Journal Article] Acarbose, an α-glucosidase inhibitor, prevents obesity and hepatic steatosis in SQSTM1/A170/p62-deficient mice2009
- Author(s)
  Okada, K., Yanagawa, T., Warabi, E., Yamastu, K., Uwayama, J., Takeda, K., Utsunomiya, H., Yoshida, H., Shoda, J., Ishii, T
- Journal Title
  
  Hepatology Res
  
  Volume: 39 Pages: 490-500
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300275
[Journal Article] Choleretic effect of Inchikoto on the cholestatic livers of patients with biliary obstruction due to biliary tract carcinoma : A randomized controlled study2009
- Author(s)
  Watanabe, S., Yokoyama, Y., Oda, K., Kokuryo, T., Shoda, J., Okada, K., Utsunomiya, H., Nagino, M
- Journal Title
  
  Hepatology Res
  
  Volume: 39 Pages: 247-255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300275
[Journal Article] Direct effects of CPT-11 and SN38 on ovarian granulosa cells.2009
- Author(s)
  Utsunomiya T, et al.
- Journal Title
  
  Molecular Medicine Reports 2
  
  Pages: 189-192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591906
[Journal Article] Nrf2 counteracts cholestatic liver injury via stimulation of hepatic defense systems2009
- Author(s)
  Okada, K., Shoda, J., Taguchi, K., Maher, J. M., Ishizaki, K., Inoue, Y., Ohtsuki, M., Goto, N., Sugimoto, H., Utsunomiya, H., Oda, K., Warabi, E., Ishii, T., Yamamoto, M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 389 Pages: 431-436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300275
[Journal Article] A novel molecular mechanism for anticancer drug-induced ovarian failure2008
- Author(s)
  Utsunomiya T, et. al.
- Journal Title
  
  International Journal of Oncology 32
  
  Pages: 991-1000
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591808
[Journal Article] Experimental characterization of recurrent ovarian immature teratoma cells after optimal surgery.2008
- Author(s)
  Tanaka, T, Toujima S, Utsunomiya T, Yukawa K, Umesaki N
- Journal Title
  
  Oncology Reports 20(1)
  
  Pages: 13-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591906
[Journal Article] 早発卵巣不全患者の1不妊治療経験2008
- Author(s)
  宇都宮智子、田中哲二、粉川克司、梅咲直彦
- Journal Title
  
  産婦人科の進歩 60
  
  Pages: 19-21
- NAID
  130001223046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591906
[Journal Article] 外来診療患者の内分泌所見からみた閉経後卵巣のエストロゲン産生能力2008
- Author(s)
  田中哲二、宇都宮智子、梅咲直彦
- Journal Title
  
  産婦人科の進歩 60
  
  Pages: 24-26
- NAID
  130001223048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591906
[Journal Article] A novel molecular mechanism for anticancer drug-induced ovarian failure : Irinotecan HCL, and anticancer topoisomerase I inhibitor, induces specific FasL expression in granulosa cells of large ovarian follicles to chance follicular apoptosis.2008
- Author(s)
  Utsunomiya T, Tanaka, T, Utsunomiya H, Umesaki N.
- Journal Title
  
  International Journal of Oncology 32
  
  Pages: 991-1000
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591906
[Journal Article] Irinotecan HCL, an anticancer topoisomerase I inhibitor, frequently induces ovarian failure in premenopausal and perimonopausal women.2008
- Author(s)
  Tanaka, T, Utsunomiya T, Utsunomiya H, Umesaki N
- Journal Title
  
  Oncology Reports 19
  
  Pages: 1123-1133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591906
[Journal Article] A novel molecular mechanism for anticancer drug-induced ovarian failure2008
- Author(s)
  Utsunomiya T, et. al.
- Journal Title
  
  International Journal of Oncology 32
  
  Pages: 991-1000
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591906
[Journal Article] Topoisomerase I inhibitor誘発卵巣顆粒膜細胞アポトーシスにおけるBCL-2 familyの意義2007
- Author(s)
  宇都宮智子, ほか
- Journal Title
  
  日本受精着床学会雑誌 24(1)
  
  Pages: 38-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591808
[Journal Article] Topoisomerase I inhibitor誘発卵巣顆粒騰細胞アポトーシスにおけるBCL-2familyの意義2007
- Author(s)
  宇都宮智子, ほか
- Journal Title
  
  日本受精着床学会雑誌 24(1)
  
  Pages: 38-42
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591808
[Journal Article] Topoisomerase I inhibitor誘発卵巣顆粒膜細胞アポートーシスにおけるBCL-2 familyの意義2007
- Author(s)
  宇都宮智子ほか
- Journal Title
  
  日本受精着床学会雑誌 24(1)(印刷中)
- Data Source
  KAKENHI-PROJECT-18591808
[Journal Article] Expression of BCL-2 and BAX products in the apoptotic large ovarian follicular granulosa cells treated with topoisomerase I inhibitor, irinotecan HCl2007
- Author(s)
  Utsunomiya T, et. al.
- Journal Title
  
  Journal of Fertlizarion and Implantation 24
  
  Pages: 38-42
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591808
[Journal Article] 抗癌剤誘発卵巣障害を予防するためのGnRH agonist療法とGNRH agonist感受性の個人差2007
- Author(s)
  田中哲二、宇都宮智子、南佐和子、八木重孝、粉川克司、梅咲直彦、宇都宮洋才
- Journal Title
  
  日本受精着床学会雑誌 24(1)
  
  Pages: 54-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591906
[Journal Article] Topoisomerase I inhibitor誘発卵巣顆粒膜細胞アポトーシスにおけるBCL-2 familyの意義2007
- Author(s)
  宇都宮智子, ほか
- Journal Title
  
  日本受精着床学会雑誌 24(1)
  
  Pages: 38-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591906
[Journal Article] Topoisomerase I inhibitor誘発卵巣顆粒膜細胞アポトーシスにおけるBCL-2familyの発現2007
- Author(s)
  宇都宮智子、田中哲二、梅咲直彦、宇都宮洋才
- Journal Title
  
  日本受精着床学会雑誌 24(1)
  
  Pages: 38-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591906
[Journal Article] Endometriosis and leptin.2006
- Author(s)
  Tanaka T, Utsunomiya T, Umesaki N
- Journal Title
  
  HORMONE FRONTIER IN GYNECOLOGY 13(3)
  
  Pages: 55-63
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591751
[Journal Article] Personalized GnRHa therapy for extraperitoneal endometriosis.2006
- Author(s)
  Tanaka T, Utsunomiya T, et al.
- Journal Title
  
  Jpn J Endometriosis 27
  
  Pages: 123-126
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591751
[Journal Article] 子宮内膜症とレプチン2006
- Author(s)
  田中哲二, 宇都宮智子, 梅咲直彦
- Journal Title
  
  HORMONE FRONTIER IN GYNECOLOGY 13(3)
  
  Pages: 55-63
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591751
[Journal Article] 腹腔外子宮内膜症に対するテーラーメイドGnRHa療法2006
- Author(s)
  田中哲二, 宇都宮智子, ほか
- Journal Title
  
  エンドメトリオーシス研究会会誌 27
  
  Pages: 123-126
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591751
[Journal Article] 存続hCG血症に対する子宮卵巣機能障害を回避するための選択的化学療法2006
- Author(s)
  宇都宮智子ほか
- Journal Title
  
  日本受精着床学会雑誌 23(1)
  
  Pages: 239-245
- Data Source
  KAKENHI-PROJECT-18591808
[Journal Article] 腹腔外子宮内膜症に対するテーラーメイドGnRHa療法2006
- Author(s)
  田中哲二, 宇都宮智子, ほか
- Journal Title
  
  エンドメトリオーシス研究会 27
  
  Pages: 123-126
- Data Source
  KAKENHI-PROJECT-17591751
[Journal Article] 5 Kihira T, Utunomiya H, Kondo T. Expression of FKBP12 and ryanodine receptors (RyRs) in the spinal cord of MND patients.2005
- Author(s)
  Kihira T, Utunomiya H, Kondo T.
- Journal Title
  
  ALS and Other motor neuron disorders 6
  
  Pages: 94-99
- Data Source
  KAKENHI-PROJECT-16590511
[Presentation] ジャバラ果皮由来ポリメトキシフラボノイドの抗肥満活性2018
- Author(s)
  奥野祥治、大田時帆、宇都宮洋才、河野良平、野村幸子
- Organizer
  日本農芸化学会関西支部講演会
- Data Source
  KAKENHI-PROJECT-15K00866
[Presentation] Differential effects of Vanillin and syringaldehydde from seed of Japanese apricot on 3T3-L1 adipogenesis2016
- Author(s)
  Yoshiharu Okuno, Saki Nomura, Shohei Yamato, Ryohei Kono, Sachiko Nomura, Akihiro Maeno, Hirotoshi Utsunomiya
- Organizer
  International conference of Food Chemistry and Technology
- Place of Presentation
  Las Vegas, NV, USA
- Year and Date
  2016-11-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00866
[Presentation] Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice fed atherogenic plus high-fat diet2010
- Author(s)
  Okada K, Sugimoto H, Warabi E, Gotoh N, Takahashi H, Utsunomiya H, Ishii T, Yamamoto M, Shoda J
- Organizer
  The 8th JSH Single Topic Conference
- Data Source
  KAKENHI-PROJECT-21300275
[Presentation] 抗癌剤誘発卵巣機能傷害に対するGnRHaの予防機序2010
- Author(s)
  宇都宮智子, ほか
- Organizer
  第28回日本受精着床学会総会・学術講演会
- Place of Presentation
  パシフィコ横浜・横浜市
- Data Source
  KAKENHI-PROJECT-22591863
[Presentation] 塩酸イリノテカン(CPT-11)治療にともなう卵巣機能不全の分子生物学的機序2009
- Author(s)
  宇都宮智子、田中哲二、梅咲直彦
- Organizer
  第61回日本産婦人科学会総会・学術講演会
- Place of Presentation
  国立京都国際会館・京都市
- Data Source
  KAKENHI-PROJECT-19591906
[Presentation] 抗癌剤治療に伴う性腺機能障害の分子機序と予防療法2008
- Author(s)
  田中哲二、宇都宮智子、李莉、梅咲直彦
- Organizer
  第58回和歌山内分泌代謝研究会・講演会
- Place of Presentation
  和歌山県立医科大学、和歌山市
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19591906
[Presentation] Quick diagnosis of Japanese spotted fever using formalin-fixed, paraffin-embedded skin biopsy specimens : Comparison between real-time PCR analysis and immunohistochemistry2008
- Author(s)
  Tamakuma K, Takeda K, Miyamoto K, Inada K, Utsunomiya H, Fujita H, Mahara F, Tsutsumi Y.
- Organizer
  5^<th> International Meeting on Rickettsiae and Rickettsial Diseases
- Place of Presentation
  Marseille, France
- Year and Date
  2008-05-20
- Data Source
  KAKENHI-PROJECT-19590460
[Presentation] 日本紅斑熱の実験動物における感染実験2008
- Author(s)
  宇都宮洋才、宮本和明、奥野祥治、秋本茂、玉熊桂子、稲田健一、堤寛、馬原文彦
- Organizer
  第63回日本衛生動物学会西日本支部大会
- Place of Presentation
  神戸市
- Year and Date
  2008-11-03
- Data Source
  KAKENHI-PROJECT-19590460
[Presentation] 抗癌剤CPT-11併用化学療法中の視床下部一下垂体一卵巣内分泌系病態に関する臨床内分泌学的研究2008
- Author(s)
  田中哲二, 宇都宮智子, ほか。
- Organizer
  第60回日本産科婦人科学会学術講演会
- Place of Presentation
  横浜パシフィコ、横浜市
- Data Source
  KAKENHI-PROJECT-19591906
[Presentation] 抗癌剤CPT-11併用化学療法中の視床下部-下垂体-卵巣内分泌系病態に関する臨床内分泌学的研究2008
- Author(s)
  田中哲二、宇都宮智子、梅咲直彦
- Organizer
  第60回日本産科婦人科学会学術講演会
- Place of Presentation
  横浜パシフィコ、横浜市
- Data Source
  KAKENHI-PROJECT-19591906
[Presentation] 皮膚生検標本からの日本紅斑熱リケッチアの検出 : 免疫染色とReal-time PCR法の比較検討2008
- Author(s)
  玉熊桂子、稲田健一、堤寛、宇都宮洋才、宮本和明、秋本茂、馬原文彦
- Organizer
  第63回日本衛生動物学会西日本支部大会
- Place of Presentation
  神戸市
- Year and Date
  2008-11-03
- Data Source
  KAKENHI-PROJECT-19590460

1. SHODA Junichi (90241827)

# of Collaborated Projects: 11 results

# of Collaborated Products: 17 results
2. TANAKA Tetsuji (80275255)

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69. LI Li

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Utsunomiya Hirotoshi 宇都宮 洋才

HIROTOSHI Utsunomiya 宇都宮 洋才

UTSUNOMIYA Hirotosi 宇都宮 洋才

宇都宮 洋才 ウツノミヤ ヒロトシ

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Novel prevention of development of life style-related liver diseases and liver carcinogenesis through an activation of transcription factor induced by functional foodsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Utsunomiya Hirotoshi 宇都宮洋才

HIROTOSHI Utsunomiya 宇都宮洋才

UTSUNOMIYA Hirotosi 宇都宮洋才

宇都宮洋才ウツノミヤヒロトシ