TAKAHASHI Hiroshi 高橋宏

Researcher Number	70236313
Other IDs
Affiliation (based on the past Project Information) *help	2011 – 2012: 筑波大学, 医学医療系, 准教授 2007 – 2010: University of Tsukuba, 大学院・人間総合科学研究科, 准教授 2006: 筑波大学, 大学院人間総合科学研究科, 助教授
Review Section/Research Field	Principal Investigator Anesthesiology/Resuscitation studies / General internal medicine (including Psychosomatic medicine) / Eating habits, studies on eating habits Except Principal Investigator Eating habits, studies on eating habits
Keywords	Principal Investigator 胆汁分泌促進 / 分子標的治療 / 転写因子 / Nrf2 / 胆汁うっ滞 / 黄疸 / 漢方製剤 / インチンコウ湯 / 周術期肝障害 / 抗酸化ストレス … More / 肝細胞保護 / 肝輸送蛋白 / オレキシン / GABA / 睡眠 / 覚醒 / セロトニン / GAVA / 麻酔・周術期 / 胆汁うっ滞性肝障害 / 漢方薬 / 輸送蛋白 / 肥満 / 脂肪性肝疾患 / 自然免疫 / 酸化ストレス / 機能性食品 / 生活習慣病 / 脂肪性肝炎 … More Except Principal Investigator 生活習慣病 / 脂肪性肝炎 / 肝発癌 / 機能性食品 / 転写因子 / Nrf2 / 分子標的治療 Less

Activation of transcription factor by functional food constituents inhibits the onset and progression of obesity-related liver diseases through attenuating the enhanced innate immunity levels.Principal Investigator
- Principal Investigator
  
  TAKAHASHI Hiroshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  University of Tsukuba
Novel prevention of development of life style-related liver diseases and liver carcinogenesis through an activation of transcription factor induced by functional foods
- Principal Investigator
  
  UTSUNOMIYA Hirotoshi, 中原朗
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  Wakayama Medical University
  University of Tsukuba
麻酔・周術期の胆汁うっ滞性肝障害―漢方薬の転写因子賦活化による新しい肝保護効果Principal Investigator
- Principal Investigator
  
  高橋宏
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Tsukuba
Roles of orexin-producing neurons in awakening from anesthesia : Analyses using various genetically-modified micePrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Hiroshi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Tsukuba
漢方製剤生薬成分の胆汁うっ滞に対する胆汁分泌促進と肝保護の新しい効果と分子機構Principal Investigator
- Principal Investigator
  
  高橋宏
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  University of Tsukuba

All 2012 2010 2009 Other

All Journal Article Presentation

[Journal Article] Deletion of Nrf2leads to rapid progression of steatohepatitis in mice fed atherogenic plus high-fat diet2012
- Author(s)
  Okada K, Warabi E, Sugimoto H, Horie M,Gotoh N, Tokushige K, Hashimoto E,Utsunomiya H, Takahashi H,Ishii T,Yamamoto M, Shoda J
- Journal Title
  
  J Gastroenterol
  
  Volume: 48 Issue: 5 Pages: 620-632
- DOI
  10.1007/s00535-012-0659-z
- NAID
  10031177013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300260, KAKENHI-PROJECT-23300250, KAKENHI-PROJECT-23660033, KAKENHI-PROJECT-24390488, KAKENHI-PROJECT-24650436, KAKENHI-PROJECT-24659104
[Journal Article] Selective loss of GABA_B receptors in orexin/hypocretin-producing neurons results in disrupted sleep/wakefulness architecture2009
- Author(s)
  Matsuki, T., Nomiyama, M, Takahira, H., Hirashima, N., Kilduff, T. S., Kunita, S., Takahashi, S., Yagami, K., Bettler, B., Yanagisawa, M., Sakurai, T.
- Journal Title
  
  Proc.Natl.Acad.,Sci.,USA. 106
  
  Pages: 4459-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390402
[Journal Article] InchinKoto, a herbal medicine, and its ingredients dually exert Mrp2/MRP-2-mediated choleresis and Nrf2-mediated antioxidative action in rar livers
- Author(s)
  Okada K, Shoda J, Takahashi H, et al.
- Journal Title
  
  American Journal Physioiogy Gastrointestinal Liver Physiology (In press)
- Data Source
  KAKENHI-PROJECT-18659196
[Presentation] Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice fed atherogenic plus high-fat diet2010
- Author(s)
  Okada K, Sugimoto H, Warabi E, Gotoh N, Takahashi H, Utsunomiya H, Ishii T, Yamamoto M, Shoda J
- Organizer
  The 8th JSH Single Topic Conference
- Data Source
  KAKENHI-PROJECT-21300275

1. SHODA Junichi (90241827)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
2. YANAGAWA Toru (10312852)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. UTSUNOMIYA Hirotoshi (60264876)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
4. ISHII Tetsuro (20111370)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. SAKURAI Takeshi (60251055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. IRUKAYAMA Yoko (90312834)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YAMAMOTO Masayuki (50166823)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. OKAMOTO Yoshikazu (90420083)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 中原朗 (90114107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 桜井武

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAKAHASHI Hiroshi 高橋 宏

Research Projects

Research Products

Co-Researchers

Activation of transcription factor by functional food constituents inhibits the onset and progression of obesity-related liver diseases through attenuating the enhanced innate immunity levels.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Novel prevention of development of life style-related liver diseases and liver carcinogenesis through an activation of transcription factor induced by functional foods

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

麻酔・周術期の胆汁うっ滞性肝障害―漢方薬の転写因子賦活化による新しい肝保護効果Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of orexin-producing neurons in awakening from anesthesia : Analyses using various genetically-modified micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

漢方製剤生薬成分の胆汁うっ滞に対する胆汁分泌促進と肝保護の新しい効果と分子機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Deletion of Nrf2leads to rapid progression of steatohepatitis in mice fed atherogenic plus high-fat diet2012

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Selective loss of GABA_B receptors in orexin/hypocretin-producing neurons results in disrupted sleep/wakefulness architecture2009

Author(s)

Journal Title

Data Source

[Journal Article] InchinKoto, a herbal medicine, and its ingredients dually exert Mrp2/MRP-2-mediated choleresis and Nrf2-mediated antioxidative action in rar livers

Author(s)

Journal Title

Data Source

[Presentation] Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice fed atherogenic plus high-fat diet2010

Author(s)

Organizer

Data Source

TAKAHASHI Hiroshi 高橋宏