Miyazaki Tadaaki 宮崎忠昭

… Alternative Names

宮崎忠昭ミヤザキタダアキ

MIYAZAKI Tadaaki 宮崎忠昭

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Researcher Number	60272431
Other IDs
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Affiliation (Current)	2022: 北海道大学, 遺伝子病制御研究所, 特任教授
Affiliation (based on the past Project Information) *help	2012 – 2013: 北海道大学, 遺伝子病制御研究所, 特任教授 2011: 北海道大学, 遺伝子病制御研究所, 教授 2005 – 2006: Hokkaido Univ., Research Center for Zoonosis Control, Prof, 人獣共通感染症リサーチセンター, 教授 2002 – 2005: 北海道大学, 遺伝子病制御研究所, 助教授 1997: University of Tokyo Graduate School of Medicine, Department of Immunology, Assis, 大学院・医学系研究科, 助手 1996 – 1997: 東京大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Biological Sciences / Immunology / Immunology Except Principal Investigator Immunology / Biophysics / Experimental pathology
Keywords	Principal Investigator IL-2 / IL-2R / アポトーシス / Pyk2 / TNF / DAP3 / CLIPR-59 / c-myc遺伝子 / 成人T細胞白血病 / BAG-1 … More / Jak3 / Jak1 / DR6 / c-myc / bcl-2 / ATL / SHP-2 / DR4,5,6 / LKB1 / LIP1 / TRAIL / src型チロシンキナーゼ / Jak3キナーゼ / IL-2Rγ鎖膜近傍領域 / チロシンキナーゼ / stat5 / 細胞増殖 / 遺伝子 / 癌 / シグナル伝達 / 免疫学 / anoikis / インフルエンザ / インターフェロン / ウイルス / Fas / SIVA1 / p40tax-1 / IL-2受容体 / Lyn / JAB / HTLV-Iウイルス / p40^<tax-1> / lck / p40tax / デスレセプター / NF-kB / death receptor / apoptosis … More Except Principal Investigator IRF-1 / IL-2 / 転写因子 / シグナル伝達 / p53 / 癌抑制遺伝子 / アポトーシス / CDK抑制因子p21 / IL-2シグナル伝達 / p40^<tax-1> / インターフェロン / サイトカイン / オステオポンチン / IFN-γ / Pyk2 / Stat1 / Jakキナーゼ / IL-2受容体 / IRFファミリー転写制御因子 / NK細胞 / 骨髄微小環境 / ウイルス感染 / IFN-α / β / IL-15 / 癌抑制因子 / lysyl oxidase / bcl-2 / IRF-2 / p48 / 細胞周期 / チロシンキナーゼ / 遺伝子ノックアウトマウス / 誘導型NO合成酵素 / 情報伝達 / プロスタグランジン受容体 / オピオイド受容体 / G蛋白共役型受容体 / インターロイキン2受容体 / ミッドカイン / ペイシジン / 自己免疫性疾患 / ミドカイン / ベイシジン / 自己免疫生疾患 / 免疫制御 / 遺伝子発現 / 生体防御 / ナチュラルキラー細胞 / 癌 / インターロイキン2 / T細胞 / TH1 / IL-12 / Immune system regulation / Interferons / Gene expression / Signal transduction / Tumor suppressor / Host difense / 蛍光相関分光法 / 蛍光測定 / グルココルチコイドレセプタ / 細胞質 / 核蛋白質 / 微環境 / レーザー走査型蛍光顕微鏡 / レーザー走査型顕微鏡 / グルココルチコイドレセプター / レーザ走査型顕微鏡 / fluorescence correlation spectroscopy / fluorescence measurement / transcriptional factor / glucocoticoide receptor / cytosol / nuclar protein / microenvironment / laser scanning microscope / 中和抗体 / インテグリン / 関節リウマチ / siRNA / 脱接着 / 癌転移 / RNAアプタマー / Osteopontin / neutralizing antibody / rheumatoid arthritis / integrin Less

ウイルス感染に対する生体防御機構およびアポトーシス誘導機構の解明Principal Investigator
- Principal Investigator
  
  宮崎忠昭
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Hokkaido University
Clarification of the mechanisms for cell death regulation by DAP3 and CLIPR59, new binding proteins to death receptorsPrincipal Investigator
- Principal Investigator
  
  MIYAZAKI Tadaaki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Hokkaido University
Molecular basis for the control of intractable diseases through manipulation of osteopontin function.
- Principal Investigator
  
  UEDE Toshimitsu
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Experimental pathology
- Research Institution
  HOKKAIDO UNIVERSITY
TNFファミリー分子とサイトカインによるアポトーシスと増殖のシグナル伝達機構解明Principal Investigator
- Principal Investigator
  
  宮崎忠昭
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
Development of the multi-point fluorescence correlation spectroscope and analysis of molecular interaction in living cell
- Principal Investigator
  
  KINJO Masataka
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  Hokkaido University
TNFファミリー分子及びサイトカインを介するアポトーシス増殖シグナル伝達機構解明Principal Investigator
- Principal Investigator
  
  宮崎忠昭
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
生体防御と癌化を制御する遺伝子群の研究
- Principal Investigator
  
  TANIGUCHI Tadatsugu
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
  Osaka University
細胞膜情報交換系の構造、機能解析と個体レベルでの役割
- Principal Investigator
  
  市川厚
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
チロシンキナーゼを介するサイトカインによるシグナル伝達機構に関する研究Principal Investigator
- Principal Investigator
  
  宮崎忠昭
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
チロシンキナーゼを介するサイトカインによるシグナル伝達機構に関する研究Principal Investigator
- Principal Investigator
  
  宮崎忠昭
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Molecular analysis of proliferative signal transduction by cytokinePrincipal Investigator
- Principal Investigator
  
  MIYAZAKI Tadaaki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  University of Tokyo
Analysis of the genetic network in the host difence system.
- Principal Investigator
  
  TANIGUCHI Tadatsugu
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Immunology
- Research Institution
  University of Tokyo

All 2013 2012 2011 2007 2004

All Journal Article Presentation Book

[Book] 北海道医学誌2013
- Author(s)
  藤倉大輔　伊藤誠敏　千葉聖子　上出利光　宮崎忠昭
- Total Pages
  1
- Publisher
  株式会社　響文社
- Data Source
  KAKENHI-PROJECT-23590559
[Book] 北海道医学誌2013
- Author(s)
  藤倉大輔　伊藤誠敏　千葉聖子　上出利光　宮崎忠昭
- Total Pages
  1
- Publisher
  株式会社響文社
- Data Source
  KAKENHI-PROJECT-23590559
[Book] Advances in Genetics Research.Volume 92012
- Author(s)
  Daisuke Fujikura ,Tadaaki Miyazaki
- Publisher
  NOVA Publishers
- Data Source
  KAKENHI-PROJECT-23590559
[Book] 日本薬理学雑誌2012
- Author(s)
  宮崎忠昭
- Publisher
  株式会社サンエムカラー
- Data Source
  KAKENHI-PROJECT-23590559
[Book] 日本東洋医学雑誌2012
- Author(s)
  宮崎忠昭
- Publisher
  蔦友印刷株式会社
- Data Source
  KAKENHI-PROJECT-23590559
[Book] BIO INDUSTRY2012
- Author(s)
  塩崎拓也　原田種展　若林一夫　山名英明　三好哲夫　白井正孝　小松俊彦　宮崎忠昭
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-23590559
[Journal Article] T Type-I interferon is critical for FasL expression on lung cells to determine the severity of influenza2013
- Author(s)
  Fujikura D, Chiba S, Muramatsu D, Kazumata M, Nakayama Y, Kawai T, Akira S, Kida H, Miyazaki T
- Journal Title
  
  Plos one
  
  Volume: 8（2）
- DOI
  10.1371/journal.pone.0055321
- NAID
  120005228345
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590559, KAKENHI-PROJECT-23689030, KAKENHI-PROJECT-23790317
[Journal Article] Enterococcus faecalis FK-23 affects alveolar-capillary permeability to attenuate leukocyte influx in lung after influenza virus infection2013
- Author(s)
  Fukada K, Fujikura D, Nakayama Y, Kondoh M, Shimada T, Miyazaki T
- Journal Title
  
  SpringerPlus
  
  Volume: 2(269)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590559
[Journal Article] Pathological examination of lung tissues in influenza a virus-infected mice.2012
- Author(s)
  Muto NA, Sunden Y, Hattori T, Fujikura D, Nakayama Y, Miyazaki T, Maruyama M, Kimura T, Sawa H.
- Journal Title
  
  Jpn J Infect Dis.
  
  Volume: 65(5) Pages: 383-391
- NAID
  130001931846
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590559
[Journal Article] Effect of Water-Soluble Fraction from Lysozyme-Treated Enterococcus faecalis FK-23 on Mortality Caused by Influenza A Virus in Mice2012
- Author(s)
  Kondoh M, Fukada K, Fujikura D, Shimada T, Suzuki Y, Iwai A, Miyazaki T.
- Journal Title
  
  Viral Immunol
  
  Volume: 25(1) Pages: 86-90
- DOI
  10.1089/vim.2011.0056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590559, KAKENHI-PROJECT-23790317
[Journal Article] Osteopontin is critical to determine symptom severity of influenza through the regulation of NK cell population.2012
- Author(s)
  Sato K, Iwai A, Nakayama Y, Morimot- o J, Takada A, Maruyama M, Kida H, Uede T, Miyazaki T
- Journal Title
  
  Biochemical and Biophysical Research Communication
  
  Volume: 417 Pages: 274-279
- DOI
  10.1016/j.bbrc.2011.11.100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390113, KAKENHI-PROJECT-23590559
[Journal Article] Effect of water-soluble fraction from lysozyme-treated Enterococcus faecalis FK-23 on mortality caused by influenza A virus in mice.2012
- Author(s)
  Fujikura D
- Journal Title
  
  Cell Death and Disease
  
  Volume: 52 Pages: 9310-9315
- DOI
  10.1038/cddis.2012.3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390113, KAKENHI-PROJECT-23590559, KAKENHI-PROJECT-23790317
[Journal Article] A small scale study on the effects of oral administration of the β-glucan produced by Aureobasidium pullulans on milk quality and cytokine expressions of Holstein cows, and on bacterial flora in the intestines of Japanese black calves.2012
- Author(s)
  Uchiyama H, Iwai A, Asada Y, Muramatsu D, Aoki S, Kawata K, Kusano K, Nagashima K, Yasokawa D, Okabe M, Miyazaki T.
- Journal Title
  
  BMC Res. Notes.
  
  Volume: 5 Pages: 189-189
- DOI
  10.1186/1756-0500-5-189
- NAID
  120005855953
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590559
[Journal Article] β-Glucan Derived from Aureobasidium pullulans Is Effective for the Prevention of Influenza in Mice.2012
- Author(s)
  Muramatsu D, Iwai A, Aoki S, Uchiyama H, Kawata K, Nakayama Y, Nikawa Y, Kusano K, Okabe M, Miyazaki T.
- Journal Title
  
  PLoS One
  
  Volume: 7(7)
- DOI
  10.1371/journal.pone.0041399
- NAID
  120004689036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590559
[Journal Article] Loss of osteopontin perturbs the epithelial-mesenchymal transition in an injured mouse lens epithelium.2007
- Author(s)
  S.Saika, K.Shirai, O.Yamanaka, KI.Miyazaki, Y.Okada, A.Kitano, KC.Flanders, S.Kon, T.Uede, WW.Kao, SR.Rittling, DT.Denhardt, Y.Ohnishi
- Journal Title
  
  Lab Invest. 87
  
  Pages: 130-138
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209014
[Journal Article] Functional role of death associated protein 3 (DAP3) in anoikis.2004
- Author(s)
  T.Miyazaki, M.Shen, D.Fujikura, N.Tosa, S.Kon, T.Uede, JC.Reed
- Journal Title
  
  J Biol Chem. 279
  
  Pages: 44667-44672
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209014
[Journal Article] Molecular dynamics of STAT3 on IL-6 signaling pathway in living cells2004
- Author(s)
  Kenji Watanabe, Kenta Saito, Masataka Kinjo, Tadashi Matsuda, Mamoru Tamura, Shigeyuki Kon, Toshimitsu Uede, Tadaaki Miyazaki
- Journal Title
  
  Biochem.Biophys.Res Comm 324
  
  Pages: 1264-1273
- Data Source
  KAKENHI-PROJECT-15370062
[Journal Article] Functional role of death associated protein 3 (DAP3) in anoikis.2004
- Author(s)
  T.Miyazaki
- Journal Title
  
  J Biol Chem. 279
  
  Pages: 44667-44672
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16209014
[Journal Article] Osteopontin affects the persistence of beta-glucan-induced hepatic granuloma formation and tissue injury through two distinct mechanisms.2004
- Author(s)
  J.Morimoto, M.Inobe, C.Kimura, S.Kon, H.Diao, M.Aoki, T.Miyazaki, DT.Denhardt, S.Rittling, T.Uede
- Journal Title
  
  Int Immunol. 16
  
  Pages: 477-488
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209014
[Presentation] Lactobacillus helveticus SBT2171によるリンパ球の増殖抑制作用・機構の解明2013
- Author(s)
  細谷知広（宮崎忠昭）
- Organizer
  乳酸菌学会2013年度大会
- Place of Presentation
  北海道大学学術交流会（札幌市）
- Data Source
  KAKENHI-PROJECT-23590559
[Presentation] Lactobacillus gasseri SBT2055 投与による肺および腸管の免疫機能調節機構2013
- Author(s)
  中山洋佑(宮崎忠昭)
- Organizer
  第17回腸内細菌学会
- Place of Presentation
  北里大学薬学部「コンベションホール」
- Data Source
  KAKENHI-PROJECT-23590559
[Presentation] インフルエンザの病態形成機構と生薬、グルカン及び乳酸菌による予防効果2012
- Author(s)
  宮崎忠昭
- Organizer
  第85回　日本薬理学会年会(招待講演)
- Place of Presentation
  国立京都国際会館（京都府）
- Data Source
  KAKENHI-PROJECT-23590559
[Presentation] The Ras -P13K Signaling Pathway is lnvolved in the Uptake of Exogenous Factors into Cells2012
- Author(s)
  Tsuda, Tomoe Hattori, Junko Sasaki, Takehiro Sasaki, Tadaaki Miyazaki, Yusuke Ohba.
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場（福岡県）
- Data Source
  KAKENHI-PROJECT-23590559
[Presentation] 腫瘍転移抑制薬開発を目指したTNFファミリー分子及びbeta2-glycoprotein Iの機能解明2012
- Author(s)
  宮崎忠昭
- Organizer
  金沢大学がん進展制御研究所・北海道大学遺伝子病制御研究所　ジョイントシンポジウム
- Place of Presentation
  北海道大学（札幌市）
- Data Source
  KAKENHI-PROJECT-23590559
[Presentation] Preventive effect of oral administration of Lactobacillus gasseri SBT2055 against influenza A virus infection2012
- Author(s)
  NAKAYAMA Yousuke,SAKAI Fumihiko,SHIOZAKI Takuya,HOSOYA Tomohiro,NAKAGAWA Hosako,MIYAZAKI Tadaaki
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸国際会議場（兵庫県）
- Data Source
  KAKENHI-PROJECT-23590559
[Presentation] インフルエンザの病態形成機構とその予防・治療への生薬・天然物成分の活用2011
- Author(s)
  宮崎忠昭
- Organizer
  第62回　日本東洋医学会学術総会　(招待講演)
- Place of Presentation
  札幌コンベションセンター（北海道）
- Data Source
  KAKENHI-PROJECT-23590559

1. TANIGUCHI Tadatsugu (50133616)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. TANAKA Nobuyuki (80222115)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. TAKI Shinsuke (50262027)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KON Shigeyuki (90344499)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. KINJO Masataka (70177971)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. TAMURA Mamoru (80089888)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. NISHIMURA Goro (30218193)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NOMURA Yasutomo (80237883)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. UEDE Toshimitsu (00160185)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. ONO Etsurou (00160903)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. YOKOSAKI Yasuyuki (80210607)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 原田久士 (10222233)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 南康博 (70229772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 市川厚 (10025695)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 門松健治 (80204519)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 藤井穂高 (30302665)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 佐藤公道 (80025709)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 芳賀達也 (30011646)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 牛首文隆 (50243035)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 松田正 (20212219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 丸山光生 (00212225)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 岩渕和也 (20184898)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 浅野善博 (70114353)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 南波昭宏

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 藤倉大輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Miyazaki Tadaaki 宮崎 忠昭

宮崎 忠昭 ミヤザキ タダアキ

MIYAZAKI Tadaaki 宮崎 忠昭

Research Projects

Research Products

Co-Researchers

ウイルス感染に対する生体防御機構およびアポトーシス誘導機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clarification of the mechanisms for cell death regulation by DAP3 and CLIPR59, new binding proteins to death receptorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular basis for the control of intractable diseases through manipulation of osteopontin function.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

TNFファミリー分子とサイトカインによるアポトーシスと増殖のシグナル伝達機構解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of the multi-point fluorescence correlation spectroscope and analysis of molecular interaction in living cell

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

TNFファミリー分子及びサイトカインを介するアポトーシス増殖シグナル伝達機構解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

生体防御と癌化を制御する遺伝子群の研究

Principal Investigator

Project Period (FY)

Research Category

Research Institution

細胞膜情報交換系の構造、機能解析と個体レベルでの役割

Principal Investigator

Project Period (FY)

Research Category

Research Institution

チロシンキナーゼを介するサイトカインによるシグナル伝達機構に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

チロシンキナーゼを介するサイトカインによるシグナル伝達機構に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Molecular analysis of proliferative signal transduction by cytokinePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the genetic network in the host difence system.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 北海道医学誌2013

Author(s)

Total Pages

Publisher

Data Source

[Book] 北海道医学誌2013

Miyazaki Tadaaki 宮崎忠昭

宮崎忠昭ミヤザキタダアキ

MIYAZAKI Tadaaki 宮崎忠昭