OHYAMA Tohru 大山徹

Researcher Number	60318178
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2011 – 2012: 東京農業大学, 生物産業学部, 教授 2007 – 2008: Tokyo University of Agriculture, Department of Bioindustry, Professor 2006: 東京農業大学, 生物産業学部 2003 – 2005: 東京農業大学, 生物産業学部, 教授
Review Section/Research Field	Principal Investigator Biomedical engineering/Biological material science / Structural biochemistry Except Principal Investigator Applied veterinary science / Bacteriology (including Mycology)
Keywords	Principal Investigator タンパク質間相互作用 / X線結晶解析 / ボツリヌス毒素 / electron microscopic observation / X-ray crystallographic analysis / Drug delivery system / protein-protein interaction / botulinum toxin / タンパク質三次元構造 / 電子顕微鏡解析 … More / 電子顕微鏡観察 / 薬物送達システム / Protein-protein interaction / Protein complex / X-ray crystallography / Subunit structure / Botulinum toxin / タンパク間相互作用 / タンパク質問相互作用 / タンパク質複合体 / サブユニット構造 … More Except Principal Investigator 小腸上皮細胞 / ボツリヌス毒素複合体 / 糖鎖 / 感染症 / 病態生理学 / ボツリヌス症 / ボツリヌス毒素 / シアル酸 / 受容体 / ボツリヌス食中毒 / 細菌学(含真菌学) / トランスサイトーシス / ボツリヌス中毒 / 疾病予防 / 吸収 / 病体生理 / 病態生理 / 細菌 / 獣医学 / 獣医公衆衛生 Less

Identification of the botulinum toxin receptor protein on the intestinal epithelial cells
- Principal Investigator
  
  WATANABE Toshihiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Tokyo University of Agriculture
Study on development of sugar feeding method that prevents animal botulism
- Principal Investigator
  
  NIWA Koichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied veterinary science
- Research Institution
  Tokyo University of Agriculture
Study on the invasion of botulinum toxin protein via intestinal epithelial cells in botulism.
- Principal Investigator
  
  NIWA Koichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied veterinary science
- Research Institution
  Tokyo University of Agriculture
Construction of innovated drug delivery system for proteins and peptides by alteration of botulinum toxin complexPrincipal Investigator
- Principal Investigator
  
  OHYAMA Tohru
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo University of Agriculture
Studies on the Interaction between Subunits of the Botulinum Toxin Complex and X-Ray CrystallographyPrincipal Investigator
- Principal Investigator
  
  OHYAMA Tohru
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Tokyo University of Agriculture

All 2011 2010 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book

[Book] Structure and Function of the Clostridium botulinum Serotypes C and D Toxin Complex.2005
- Author(s)
  Watanabe T, Sagane Y, Mutoh S, Suzuki T, Hasegawa K, Kouguchi H, Ohyama T.
- Total Pages
  17
- Publisher
  Research Signpost
- Data Source
  KAKENHI-PROJECT-15570103
[Book] Structure and function of the Clostridium botulinum serotypes C and D toxin complex2005
- Author(s)
  Watanabe T., Sagane, Y., Mutoh, S., Suzuki, T., Hasegawa, K., Kouguchi, H., Ohyama, T.
- Publisher
  Research Signpost
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570103
[Journal Article] HA-33 facilitates transport of the serotype D botulinum toxin across a rat intestinal epithelial cell monolayer2011
- Author(s)
  Ito, H., Sagane, Y., Miyata, K., Inui, K., Matsuo, T., Horiuchi, R., Ikeda, T., Suzuki, T., Hasegawa, K., Kouguchi, K., Oguma, K., Niwa, K., Ohyama, T., Watanabe T.
- Journal Title
  
  FEMS Immunology Medicul Microbiology
  
  Volume: 61 Issue: 3 Pages: 323-331
- DOI
  10.1111/j.1574-695x.2011.00779.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J08286, KAKENHI-PROJECT-11J10275, KAKENHI-PROJECT-21580383, KAKENHI-PROJECT-22590405
[Journal Article] Characterization of sugar recognition by the toxin complex produced by Clostridium botulinum serotype C variant strain Yoichi2011
- Author(s)
  Matsuo, T., Miyata, K., Inui, K., Ito, H., Horiuchi, R., Suzuki, T., Yoneyama, T., Oguma, K., Niwa, K., Watanabe, T., Ohyama, T.
- Journal Title
  
  FEMS Immunology Medicul Microbiology
  
  Volume: 63 Issue: 1 Pages: 35-43
- DOI
  10.1111/j.1574-695x.2011.00825.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J08286, KAKENHI-PROJECT-11J10275, KAKENHI-PROJECT-21580383, KAKENHI-PROJECT-22590405
[Journal Article] Sialic acid-dependent binding and transcytosis of serotype D botulinum neurotoxin and toxin complex in rat intestinal epithelial cells2010
- Author(s)
  Niwa, K., Yoneyama, T., Ito, H., Taira, M., Chikai, T., Kouguchi, H., Suzuki, T., Hasegawa, K., Miyata, K., Inui, K., Ikeda, T., Watanabe, T. and Ohyama, T.
- Journal Title
  
  Vet. Microbiol
  
  Volume: 141 Pages: 312-320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580383
[Journal Article] Clostridium botulinum Serotype D neurotoxin and toxin complex bind to bovine aortic endothelial cells via sialic acid2008
- Author(s)
  Yoneyama, T., Miyata, K., Chikai, T., Mikami, A., Suzuki, T., Hasegawa, K., Ikeda, T., Watanabe, T., Ohyama, T. and Niwa, K
- Journal Title
  
  FEMS Immunol. Med. Microbiol 54
  
  Pages: 290-298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580364
[Journal Article] Role of non-toxic components of serotype D botulinum toxin complex in permeation through Caco-2 cell monolayer, a model for intestinal epithelium2007
- Author(s)
  Niwa, K., Koyama, K., Inoue, S., Suzuki, T., Hasegawa, K., Watanabe, T., Ikeda, T., Ohyama, T
- Journal Title
  
  FEMS. Immunol Medical Microbiol 49
  
  Pages: 346-352
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300161
[Journal Article] Improved arterial wall model by co-culturing vascular endothelial and smooth muscle Cells2007
- Author(s)
  Niwa, K., Sakai, J., Watanabe, T., Ohyama, T., Karino, T
- Journal Title
  
  In Vitro Cell. & Develop. Biol 43
  
  Pages: 17-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300161
[Journal Article] Effect of nicking in the C-terminal of heavy chain of Clostridium botulinum sserotype D neurotoxin on its toxicity and molecular properties2007
- Author(s)
  Suzuki, T., Kouguchi, H., Sato, H., Hasegawa, K., Mutoh, S., Yoneyama, T., Niwa, K., Nishikawa, A., Lee, C-J., Oguma, K., Watanabe, T., Ohyama, T
- Journal Title
  
  Protein J 26
  
  Pages: 173-181
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300161
[Journal Article] C Terminal half fragment (50 kDa) of heavy chain components of Clostridium botulinum type C and D neurotoxins can be used as an effective vaccine2007
- Author(s)
  Lee, J. C., Hwang, H. J., Sakaguchi, Y, Yamamoto, Y., Arimitsu, H., Tsuji, T., Watanabe, T., Ohyama, T., Tsuchiya, T., Oguma, K
- Journal Title
  
  Microbiol. Immunol 51
  
  Pages: 445-455
- NAID
  10020280881
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300161
[Journal Article] A Novel Subunit Structure of Clostridium botulinum Serotype D Toxin Complex with Three Extended Arms2007
- Author(s)
  Hasegawa, K., Watanabe, T., Suzuki, T., Yamano, A., Oikawa, T., Sato, Y., Kouguchi, H., Yoneyama, T., Niwa, K., Ikeda, T., Ohyama, T
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 24777-24783
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300161
[Journal Article] Cell internalization and traffic pathway of Clostridium botulinum type C neurotoxin in HT-29 cells2006
- Author(s)
  Uotsua, N., Nishikawaa, A., Watanabec, T., Ohyamac, T., Tonozukaa, T., Sakanoa, Y., Oguma, K
- Journal Title
  
  Biochim. Biophys. Acta 1763
  
  Pages: 120-128
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300161
[Journal Article] Quantitative detection of gene expression and toxin complex produced by Clostridium botulinum serotype D strain 49472006
- Author(s)
  Kouguchi, H., Suzuki, T., Hasegawa, K., Mutoh, S., Watanabe, T., Niwa, K., Yoneyama, T., Katoh, Y., Ohyama, T
- Journal Title
  
  J. Microbiol. Method 67
  
  Pages: 416-423
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300161
[Journal Article] ボツリヌス毒素の機能とそのサブユニット構造2006
- Author(s)
  大山徹
- Journal Title
  
  蛋白質・核酸・酵素 51巻、12月号
  
  Pages: 2334-2340
- NAID
  40015188928
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17300161
[Journal Article] Four molecules of 33 kDa hemagglutinin components (HA-33) of the Clostridium botulinum serotype C and D toxin complexes are required to aggregate erythrocytes2005
- Author(s)
  Mutoh, S., Suzuki, T., Hasegawa, K., Nakazawa, Y., Kouguchi, H., Sagane, Y., Niwa, K., Watanabe, T., Ohyama, T
- Journal Title
  
  Microbiology-UK 151
  
  Pages: 3847-3858
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300161
[Journal Article] Production of anti-neurotoxin antibody is enhanced by two subcomponents, HA1 and HA3b, of Clostridium botulinum type B 16S toxin-haemagglutinin2005
- Author(s)
  Lee, J. C., Yokota, K., Arimitsu, H., Hwang, H. J., Sakaguchi, Y., Cui, J., Takeshi, K., Watanabe, T., Ohyama, T., Oguma, K
- Journal Title
  
  Microbiology-UK 151
  
  Pages: 3739-3747
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300161
[Journal Article] Characterization of the interaction between subunits of the botulinum toxin complex produced by serotype D through tryptic susceptibility of the isolated components and complex forms2005
- Author(s)
  Suzuki, T., Watanabe, T., Mutoh, S., Hasegawa, K., Kouguchi, H., Fujinaga, F., Oguma, K., Ohyama, T
- Journal Title
  
  Microbiology-UK 151
  
  Pages: 1475-1483
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300161
[Journal Article] Characterization of the interaction between subunits of the botulinum toxin complex produced by serotype D through tryptic susceptibility of the isolated components and complex forms.2005
- Author(s)
  Suzuki T, Watanabe T, Mutoh S, Hasegawa K, Kouguchi H, Fujinaga F, Oguma K, Ohyama, T.
- Journal Title
  
  Microbiology -UK 151
- Data Source
  KAKENHI-PROJECT-15570103
[Journal Article] Molecular characterization of binding subcomponents of Clostridium botulinum type C progenitor toxin for intestinal cells and erythrocytes2004
- Author(s)
  Fujinaga, Y., Inoue, K., Watarai, S., Sakaguchi, Y., Arimitsu, H., Lee, J.C., Jin, Y., Matsumura, T., Kabumoto, Y., Watanabe, T., Ohyama, T., Nishikawa, A., Oguma, K.
- Journal Title
  
  Microbiology Vol.150
  
  Pages: 1529-1538
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570103
[Journal Article] Characterization of Toxin Complex Produced by a Unique Strain of Clostridium botulinum type D 4947.2004
- Author(s)
  Hasegawa K, Watanabe T, Sato H, Sagane Y, Mutoh S, Suzuki T, Yamano Y, Kouguchi H, Takeshi K, Kamaguchi A, Fujinaga Y, Oguma K, Ohyama T.
- Journal Title
  
  Protein J. 23
  
  Pages: 371-378
- Data Source
  KAKENHI-PROJECT-15570103
[Journal Article] Characterization of Toxin Complex Produced by a Unique Strain of Clostridium botulinum type D 49472004
- Author(s)
  Hasegawa, K., Watanabe, T., Sato, H., Sagane, Y., Mutoh, S., Suzuki, T., Yamano, Y., Kouguchi, H., Takeshi, K., Kamaguchi, A., Fujinaga, Y., Oguma, K., Ohyama, T.
- Journal Title
  
  Protein J. Vol.23
  
  Pages: 371-378
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570103
[Journal Article] The receptor and transporter for internalization of Clostridium botulinum type C progenitor toxin into HT-29 cells2004
- Author(s)
  Nishikawa, A., Uotsu, N., Arimitsu, H., Lee, J.C., Miura, Y., Fujinaga, Y., Nakada, H., Watanabe, T., Ohyama, T., Sakano, Y., Oguma, K.
- Journal Title
  
  Biochem.Biophys.Res.Commun. Vol.319
  
  Pages: 327-333
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570103
[Journal Article] Complete Subunit Structure of Clostridium botulinum Type D Toxin Complex via Intermediate Assembly with Nontoxic Components2003
- Author(s)
  Mutoh, S., Kouguchi, H., Sagane, Y., Suzuki, T., Hasegawa, K., Watanabe, T., Ohyama, T.
- Journal Title
  
  Biochemistry Vol.37
  
  Pages: 10991-10997
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570103
[Journal Article] Purification of Fully Activated Clostridium botulinum Serotype B Toxin for Treatment of Patients with Dystonia2003
- Author(s)
  Arimitsu, H., Inoue, K., Sakaguchi, Y., Lee, J.C., Fujinaga, Y., Watanabe, T., Ohyama, T., Hirst, R., Oguma, K.
- Journal Title
  
  Infect.Immun. Vol.71
  
  Pages: 1599-1603
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570103
[Journal Article] Molecular Characterization of GroES and GroEL Homologues from Clostridium botulinum2003
- Author(s)
  Sagane, Y., Hasegawa, K., Mutoh, S., Kouguchi, K., Suzuki, T., Sunagawa, H., Nakagawa, T., Kamaguchi, A., Okasaki, S., Nakayama, K., Watanabe, T., Oguma K., Ohyama, T.
- Journal Title
  
  J.Protein Chem. Vol.22
  
  Pages: 99-108
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570103
[Journal Article] Complete Subunit Structure of Clostridium botulinum Type D Toxin Complex via Intermediate Assembly with Nontoxic Components.2003
- Author(s)
  Mutoh S, Kouguchi H, Sagane Y, Suzuki T, Hasegawa K, Watanabe T, Ohyama T.
- Journal Title
  
  Biochemistry 37
  
  Pages: 10991-10997
- Data Source
  KAKENHI-PROJECT-15570103
[Presentation] C 型ボツリヌス毒素の小腸上皮細胞からの侵入機構の解析2010
- Author(s)
  犬井健,宮田恵多,伊藤博章,松尾 5,堀内亮太,吉田悠真,宮下慎一郎,村松将司,渡部俊弘,大山徹,丹羽光一
- Organizer
  第33回日本分子生物学会年会代 83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590405
[Presentation] C 型およびD 型ボツリヌス毒素の小腸上皮細胞の透過におけるシアル酸の役割2010
- Author(s)
  丹羽光一,伊藤博章,犬井健,宮田恵多,松尾智仁,堀内亮太,宮下慎一郎,吉田悠真,村松将司,渡部俊弘,大山徹
- Organizer
  第150回日本獣医学会学術集会
- Place of Presentation
  帯広
- Data Source
  KAKENHI-PROJECT-22590405
[Presentation] Mechanism of Clostridium botulinum type D toxin complex in binding to bovine aortic endothelial cells2007
- Author(s)
  Niwa, K., Miyata, K., Yoneyama, T., Taira, M., Mikami, A., Chikai, T., Ikeda, T., Watanabe, T., Ohyama, T
- Organizer
  BMB2007 (The 79th Annual Scientific Meeting of the Japanese Biochemical Society)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300161
[Presentation] Clostridium botulinum serotype D toxin complex binds to bovine artery endothelial cells via sialic acid moiety.2007
- Author(s)
  Yoneyama, T., Niwa, K., Miyata, K., Mikami, A., Chicai, T., Watanabe, T., Ohyama, T
- Organizer
  BMB2007 (The 79th Annual Scientific Meeting of the Japanese Biochemical Society)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300161
[Presentation] A novel electron microscopy structure of the toxin complex produced by the Clostridium botulinum serotpe D strain 49472007
- Author(s)
  Hasegawa, K., Suzuki, T., Watanabe, T., Mutoh, S., Oikawa, T., Satoh, Y., Niwa, K., Ohyama, T
- Organizer
  The 4th Takeda Science Foundation Symposium on PharmaSciences
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300161
[Presentation] A novel structure analysis of the toxin complex produced by the Clostridium botulinum serotype D June 2006,Kyoto2006
- Author(s)
  Hasegawa, K., Suzuki, T., Niwa, K., Miyata, K., Oikawa, T., Sagane, Y., Ikeda, T.,Watanabe, T., Ohyama, T
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300161
[Presentation] Characterization of the interaction regions between individual components in the botulinum toxin complex2006
- Author(s)
  Suzuki, T.,Hasegawa, K., Yoneyama, T., Miyata, K., Niwa, K., Ikeda, T., Watanabe, T., Ohyama, T
- Organizer
  16th International Microscopy Congress (IMC16)
- Place of Presentation
  Sapporo Conventional Center
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300161
[Presentation] Molecular characterization of protease responsible for nicking in botulinum neurotoxin complex.2005
- Author(s)
  Suzuki, T., Yoneyama, T., Miyata, K., Mikami, K., Chikai, T., Hasegawa, K., Niwa, K., Watanabe, T., Miyazaki, S., Ohyama, T
- Organizer
  The78th Annual Scientific Meeting of the Japanese Biochemical Society
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300161
[Presentation] Characterization of interaction between botulinum neurotoxin and notoxic components through the reconstitution of hybrid toxin complex2005
- Author(s)
  Hasegawa, K., Watanabe, T., Mutoh, S., Suzuki, T., Niwa, K., Ohyama, T
- Organizer
  The 78th Annual Scientific Meeting of the Japanese Biochemical Society
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300161
[Presentation] Characterization of trypsin like protease produced by Clostriduim botulinum type C strain Stockholm
- Author(s)
  Saitoh, R., Suzuki, T., Yoneyama, T., Mutoh, S., Hasegawa, K., Munehiro, M., Niwa, K., Watanabe, T., Ohyama, T
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300161

1. WATANABE Toshihiro (80175695)

# of Collaborated Projects: 6 results

# of Collaborated Products: 33 results
2. NIWA Koichi (20301012)

# of Collaborated Projects: 4 results

# of Collaborated Products: 18 results
3. OGURI Suguru (70277250)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. NAKAGAWA Tomoyuki (70318179)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

OHYAMA Tohru 大山 徹

Research Projects

Research Products

Co-Researchers

Identification of the botulinum toxin receptor protein on the intestinal epithelial cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on development of sugar feeding method that prevents animal botulism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the invasion of botulinum toxin protein via intestinal epithelial cells in botulism.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Construction of innovated drug delivery system for proteins and peptides by alteration of botulinum toxin complexPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the Interaction between Subunits of the Botulinum Toxin Complex and X-Ray CrystallographyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Structure and Function of the Clostridium botulinum Serotypes C and D Toxin Complex.2005

Author(s)

Total Pages

Publisher

Data Source

[Book] Structure and function of the Clostridium botulinum serotypes C and D toxin complex2005

Author(s)

Publisher

Description

Data Source

[Journal Article] HA-33 facilitates transport of the serotype D botulinum toxin across a rat intestinal epithelial cell monolayer2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characterization of sugar recognition by the toxin complex produced by Clostridium botulinum serotype C variant strain Yoichi2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sialic acid-dependent binding and transcytosis of serotype D botulinum neurotoxin and toxin complex in rat intestinal epithelial cells2010

Author(s)

Journal Title

Data Source

[Journal Article] Clostridium botulinum Serotype D neurotoxin and toxin complex bind to bovine aortic endothelial cells via sialic acid2008

Author(s)

Journal Title

Data Source

[Journal Article] Role of non-toxic components of serotype D botulinum toxin complex in permeation through Caco-2 cell monolayer, a model for intestinal epithelium2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Improved arterial wall model by co-culturing vascular endothelial and smooth muscle Cells2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Effect of nicking in the C-terminal of heavy chain of Clostridium botulinum sserotype D neurotoxin on its toxicity and molecular properties2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] C Terminal half fragment (50 kDa) of heavy chain components of Clostridium botulinum type C and D neurotoxins can be used as an effective vaccine2007

Author(s)

Journal Title

OHYAMA Tohru 大山徹