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Sano Yoshifumi  佐野 由文

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SANO Yoshifumi  佐野 由文

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Researcher Number 60322228
Affiliation (Current) 2025: 愛媛大学, 医学系研究科, 准教授
Affiliation (based on the past Project Information) *help 2016 – 2024: 愛媛大学, 医学系研究科, 准教授
2023: 愛媛大学, 医学系研究科, 教授
2014 – 2015: 愛媛大学, 医学(系)研究科(研究院), 准教授
2014: 愛媛大学, 大学院医学系研究科, 准教授
2011 – 2013: 愛媛大学, 医学部附属病院, 准教授 … More
2010: 岡山大学, 医学部歯学部附属病院, 講師
2009: Okayama University, 大学病院, 講師
2009: Okayama University, 岡山大学病院, 講師
2007 – 2008: Okayama University, Okayama University Hospital, Senior Assistant Professors
2006: 岡山大学, 医学部歯学部附属病院, 助手
2003 – 2006: 岡山大学, 医学部・歯学部附属病院, 助手
2003: Okayama University, Hospital, Assistant Prof., 医学部・歯学部付属病院, 助手
2002: Okayama University Hospital, Assistant, 医学部附属病院, 助手
2000 – 2001: 岡山大学, 医学部・附属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Basic Section 55040:Respiratory surgery-related / Respiratory surgery / Thoracic surgery / Thoracic surgery
Except Principal Investigator
Thoracic surgery / Thoracic surgery / Basic Section 55040:Respiratory surgery-related / Respiratory surgery / Basic Section 50010:Tumor biology-related
Keywords
Principal Investigator
免疫チェックポイント / Nedd8 / 免疫チェックポイント阻害剤 / PD-L1 / 翻訳後修飾 / NEDD8 / 肺癌 / 抗ドナー抗体 / 急性拒絶反応 / Neddylation … More / 肺癌細胞 / 免疫チェックポイント阻害 / 転写 / 癌免疫チェックポイント / 免疫回避機構 / 癌免疫チェックポイント阻害剤 / 肺がん / Cullin / タンパク質代謝 / 癌免疫 / 腫瘍免疫 / cyclosporine / immunofluoressence / flow cytometry / anti-donor antibodies / acute rejection / lung transplantation / サイクロスポリン / 蛍光抗体法 / フローサイトメトリー / 肺移植 / 非侵襲的診断法 / 生体肺移植 / 抗ドナー特異的抗体価 / 両側生体肺移植 / 肺移植後急性拒絶反応 / 抗ドナー抗体価 … More
Except Principal Investigator
肺移植 / 虚血再灌流障害 / 心停止ドナー / Recipient / Donor / レシピエント / ドナー / 生体部分肺移植 / 呼吸補助 / 肺癌 / 血管内皮細胞 / Arterial oxygen tension / Living-Donor Lobar Lung Transplantation / 動脈血酸素分圧 / 肺動脈圧 / Acute Lung Injury / Animal Experiment / Respiratory Failure / Liquid Ventilation / 液体換気 / 急性肺障害 / 動物実験 / 呼吸不全 / 液体呼吸 / 温虚血 / 血管 / 線維化 / 癒着 / 呼吸器外科手術 / 胸腔内癒着 / HB-EGF / 腫瘍微小環境 / 免疫療法 / PD-L1 / モデルマウス / 虚血再灌流 / 酸化ストレス / Cullin-3 / ユビキチンリガーゼ / 心停止ドナーからの肺移植 / 虚血再灌流霜害 / Heparin / Cardiac massage / Urokinese / Non-heart-beating donor / Lung transplantation / ヘパリン / 心マッサージ / ウロキナーゼ / 心臓死ドナー / Pulmonary function / Bronchial healing / Living-donor Lobar Lung Transplantation / 気管支吻合 / 気管支吻合部 / Perfluorocarbon / Membrane Oxygenator / Artificial Ventilation / Respiratory Assist / 呼吸条件 / 呼吸生理 / 医療工学 / 医療器械 / パーフロロカーボン / 完全液体呼吸 / 全液体呼吸 / パーフルオロカーボン / 膜型人工肺 / 人工呼吸 / Pulmonary artery pressure / 動脈血ガス分析 / Pulmonary arteriral pressure / Oxygen supply / Artificial device / Canine model / Pulmonary artery banding / Right heart failure / Pulmonary assist / Pulmonary replacement / Artificial lung / 胸腔内 / 臓器置換 / 膜型肺 / 人工肺 / Endotoxin / Bronchoalveolar Lavage / Local Inflammation / Cytokines / マクロファージ / 白血球 / 肺胞洗浄液 / 肺障害 / 炎症 / 液体吸収 / ラット / 実験研究 / 抗炎症効果 / エンドトキシン / 気管支肺胞洗浄 / 局所炎症 / サイトカイン / ex-vivo evaluation / 再灌流 / Ex-vivo evaluation Less
  • Research Projects

    (19 results)
  • Research Products

    (16 results)
  • Co-Researchers

    (25 People)
  •  細胞内mRNA代謝に着目した肺癌細胞免疫回避機構の解明

    • Principal Investigator
      坂尾 伸彦
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Ehime University
  •  肺癌微小環境を構築する間質細胞を標的とした新たな肺癌治療戦略

    • Principal Investigator
      桐山 洋介
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Ehime University
  •  胸膜癒着の機序解明とその制御法の開発

    • Principal Investigator
      藻利 優
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Ehime University
  •  Elucidation of a Novel Mechanism Regulating PD-L1 Expression in Lung Cancer and Its Role in Immune EvasionPrincipal Investigator

    • Principal Investigator
      Sano Yoshifumi
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Ehime University
  •  Development of therapy of pulmonary ischemia-reperfusion injury targeting ubiquitin ligase

    • Principal Investigator
      杉本 龍士郎
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Ehime University
  •  Inhibition of lung ischemia reperfusion injury by R-Spondin 3

    • Principal Investigator
      Okazaki Mikio
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory surgery
    • Research Institution
      Okayama University
      Ehime University
  •  Analysis of molecular mechanism of NEDD8-mediated regulation of PD-L1 in lung cancerPrincipal Investigator

    • Principal Investigator
      Yoshifumi Sano
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory surgery
    • Research Institution
      Ehime University
  •  Endothelial dysfunction after lung transplantation with donation after cardiac death donors

    • Principal Investigator
      Okazaki Mikio
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory surgery
    • Research Institution
      Ehime University
  •  Mechanism and inhibition of ischemia reperfusion injury after lung transplantation from donation after cardiac death

    • Principal Investigator
      OKAZAKI MIKIO
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Ehime University
  •  A large animal experimental study to establish a clinical applicable method for lung transplantation utilizing non-heart beating donors

    • Principal Investigator
      DATE Hiroshi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Thoracic surgery
    • Research Institution
      Kyoto University
  •  The serum level of de novo donor specific antibody can predict acute rejection in lung transplantation.Principal Investigator

    • Principal Investigator
      SANO Yoshifumi
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Okayama University
  •  Experimental Study on Microthrombi Formation for Lung Transplantation from Non-Heart-Beating Donor

    • Principal Investigator
      DATE Hiroshi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Okayama University
  •  Experimental Study to Develop a New Procedure for Living-Donor Lobar Lung Transplantation

    • Principal Investigator
      DATE Hiroshi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      OKAYAMA UNIVERSITY
  •  An experimental study about development of the ventilator for total liquid ventilation and its optimal respiratory setting.

    • Principal Investigator
      AOE Motoi, 清水 信義
    • Project Period (FY)
      2003 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Thoracic surgery
    • Research Institution
      Okayama University
  •  Experimental Study on Pulmonary Function and Lung Growth after Living-Donor Lobar Lung Transplantation

    • Principal Investigator
      DATE Hiroshi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Okayama University
  •  A study about total pulmonary replacement with artificial intra-thoracic implantable lung.

    • Principal Investigator
      AOE Motoi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Okayama University
  •  Expeimental Study on Pulmonary Function and Lung Growth after Living-Donor Lobar Lung Transplantation

    • Principal Investigator
      DATE Hiroshi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      OKAYAMA UNIVERSITY
  •  The relationship between anti-donor antibodies and acute rejection in lung transplantationPrincipal Investigator

    • Principal Investigator
      SANO Yoshifumi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Okayama University
  •  An experimental study about anti-local inflammation effects of liquid ventilation.

    • Principal Investigator
      SHIMIZU Nobuyoshi
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Thoracic surgery
    • Research Institution
      Okayama University

All 2022 2020 2019 2018 2017 2010 2006 2004

All Journal Article Presentation

  • [Journal Article] Suppression of inflammatory cytokines during ex vivo lung perfusion with an absorbent membrane.2010

    • Author(s)
      Kakishita T, Oto T, Hori S, Miyoshi K, Otani S, Yamamoto S, Waki N, Yoshida O, Okazaki M, Yamane M, Toyooka S, Sano Y, Miyoshi S.
    • Journal Title

      Ann Thorac Surg 89(6)

      Pages: 1773-1779

    • Data Source
      KAKENHI-PROJECT-20390367
  • [Journal Article] Optimal time for post-mortem heparinization in canine transplantation with nbn-heart-beating donors.2006

    • Author(s)
      Okazaki M, Date H, Inokawa H, Okutani D, Aokage K, Nagahiro I, Aoe M, Sano Y, Shimizu N.
    • Journal Title

      J Heart Lung Transplant 25

      Pages: 454-60

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591549
  • [Journal Article] Post-mortem administration of urokinase in canine lung transplantation from non-heart-beating donors.2006

    • Author(s)
      Sugimoto R, Date H, Sugimoto S, Okazaki M, Aokage K, Inokawa H, Aoe M, Sano Y.
    • Journal Title

      J Heart Lung Transplant 25

      Pages: 1148-53

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591549
  • [Journal Article] Bilateral native lung-sparing lobar transplantation in a canine model.2006

    • Author(s)
      Sugimoto S, Date H, Sugimoto R, Aoe M, Sano Y
    • Journal Title

      J Thorac Cardiovasc Surg 132(5)

      Pages: 1213-1218

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591398
  • [Journal Article] The technique of unilateral double lobar lung transplantation in a canine model2004

    • Author(s)
      Okutani D, Date H, Hayama M, Inokawa H, Okazaki M, Nagahiro I, Sano Y, Aoe M, Shimizu N
    • Journal Title

      J Thorac Cardiovasc Surg 127

      Pages: 563-567

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571266
  • [Presentation] タンパク質翻訳後修飾を介した肺癌細胞PD-L1の新たな発現制御機構2022

    • Author(s)
      坂尾伸彦、坂上倫久、藻利優、桐山洋介、大谷真二、岡崎幹生、豊岡伸一、佐野由文
    • Organizer
      第63回日本肺癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K09179
  • [Presentation] マウスモデルを用いた肺虚血再灌流障害の分子機序の解明2020

    • Author(s)
      薦田悠平、西田俊太、坂上倫久、岡﨑幹生、重松久之、杉本龍士郎、佐野由文、泉谷裕則
    • Organizer
      第37回日本呼吸器外科学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K09289
  • [Presentation] Expression Analysis of Programmed Death-Ligand(PD-L)1 in Large Cell Neuroendocrine Carcinoma2019

    • Author(s)
      Tomohisa Sakaue, Hirotomo Nakaoka, Mikio Okazaki, Hisayuki Shigematsu, Hironori Izutani, Yoshifumi Sano
    • Organizer
      IASLC 2019 World Conference on Lung Cancer
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10791
  • [Presentation] 肺癌におけるPD-L1の発現制御メカニズムの解析2019

    • Author(s)
      坂上倫久、中岡裕智、岡崎幹生、重松久之、杉本龍士郎、泉谷裕則、佐野由文
    • Organizer
      第60回日本肺癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K10791
  • [Presentation] 肺癌におけるHeparin-binding Epidermal Growth factor(HB-EGF)の解析2018

    • Author(s)
      坂上倫久、中岡裕智、藻利優、坂尾伸彦、岡崎幹生、重松久之、東山繁樹、佐野由文、泉谷裕則
    • Organizer
      第59回日本肺癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K10791
  • [Presentation] 高悪性度神経内分泌肺腫瘍におけるPD-L1の発現解析2018

    • Author(s)
      坂上倫久、中岡裕智、藻利優、岡崎幹生、重松久之、泉谷裕則、佐野由文
    • Organizer
      第35回日本呼吸器外科学会総会
    • Data Source
      KAKENHI-PROJECT-17K10791
  • [Presentation] 肺がん組織におけるProgrammed Death-Ligand 1(PD-L1)の発現とその制御メカニズムの解析2017

    • Author(s)
      中岡裕智、坂上倫久、藻利優、坂尾伸彦、岡崎幹生、重松久之、倉田美恵、東山繁樹、佐野由文、泉谷裕則
    • Organizer
      第34回日本呼吸器外科学会総会
    • Data Source
      KAKENHI-PROJECT-17K10791
  • [Presentation] 外科的切除した肺癌組織を用いたHeparin Binding EGF Like Growth Factor (HB-EGF)の解析2017

    • Author(s)
      坂上倫久、中岡裕智、藻利優、坂尾伸彦、 岡崎幹生、重松久之、佐野由文、泉谷裕則
    • Organizer
      第34回日本呼吸器外科学会総会
    • Data Source
      KAKENHI-PROJECT-17K10791
  • [Presentation] 肺癌細胞におけるProgrammed Death-Ligand1(PD-L1)の細胞内タンパク質代謝機序の解明2017

    • Author(s)
      坂上倫久、藻莉優、坂尾伸彦、岡崎幹生、 重松久之、東山繁樹、佐野由文、泉谷裕則
    • Organizer
      第58回日本肺癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K10791
  • [Presentation] 急性拒絶反応発症と抗ドナー特異的抗体価推移-急性拒絶発症を予見できるか2010

    • Author(s)
      三好健太郎, 佐野由文, 他
    • Organizer
      第26回日本肺および心肺移植研究会
    • Place of Presentation
      大阪
    • Year and Date
      2010-01-30
    • Data Source
      KAKENHI-PROJECT-19591626
  • [Presentation] 急性拒絶反応発症と抗ドナー特異的抗体価推移-急性拒絶反応発症を予見できるか2010

    • Author(s)
      三好健太郎, 佐野由文, 大谷真二, 脇直久, 山根正修, 大藤剛宏, 三好新一郎
    • Organizer
      第26回日本肺および心肺移植研究会
    • Place of Presentation
      大阪大学中之島センター
    • Year and Date
      2010-01-30
    • Data Source
      KAKENHI-PROJECT-19591626
  • 1.  DATE Hiroshi (60252962)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 4 results
  • 2.  AOE Motoi (80260660)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 4 results
  • 3.  OKAZAKI MIKIO (50467750)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 8 results
  • 4.  SHIMIZU Nobuyoshi (90108150)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 1 results
  • 5.  坂上 倫久 (20709266)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 9 results
  • 6.  NAGAHIRO Itaru (00311803)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 1 results
  • 7.  YAMANE Masaomi (20432643)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 8.  TOMIOKA Shinichi (30397880)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  ANDOU Akio (70222776)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  中岡 裕智 (30795464)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 11.  OTO Takahiro (40452578)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 12.  KOIKE Kaoru (10267164)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  BANDO Toru (20293954)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  TSUYOSHI Shoji (80402840)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  CHEN Fengshi (00452334)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  FUJINAGA Takuji (00444456)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  OKAMOTO Toshihiro (90467465)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  FUNAKUBO Akio (00307670)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  OKABE Kazunori (90260661)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  市場 晋吾 (30284102)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  重松 久之 (00645111)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 22.  杉本 龍士郎 (70549873)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 23.  坂尾 伸彦 (80973221)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  桐山 洋介 (40973904)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  藻利 優 (10972581)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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