Fujiwara Tohru 藤原亨

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FUJIWARA Tohru 藤原亨

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Researcher Number	60333796
Other IDs
Affiliation (Current)	2025: 岩手医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2023: 岩手医科大学, 医学部, 准教授 2016 – 2022: 東北大学, 大学病院, 講師 2014 – 2015: 東北大学, 医学(系)研究科(研究院), 講師 2012: 東北大学, 医学(系)研究科(研究院), 助教 2011 – 2012: 東北大学, 大学院・医学系研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Hematology / Molecular biology / Biological Sciences Except Principal Investigator Collagenous pathology/Allergology / Hematology
Keywords	Principal Investigator 遺伝子 / 造血幹細胞 / 造血微小環境 / GATA-2 / 骨髄異形成症候群 / 鉄芽球性貧血 / 後天性鉄芽球性貧血 / 転写因子 / 赤血球分化 / 貧血 / 血液内科学 / 転写 … More Except Principal Investigator … More 転写因子GATA2 / 肺動脈性肺高血圧症 / 転写因子GATA3 / 2型自然リンパ球 / 内科 / 内科学 / Toll様受容体 / 骨髄由来免疫抑制細胞 / 転写因子ＧＡＴＡ２ / マクロファージ / 単球 / 肺高血圧 Less

転写因子GATA-2を介した造血幹細胞と造血微小環境の機能的連関の解明Principal Investigator
- Principal Investigator
  
  藤原亨
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Iwate Medical University
  Tohoku University
Elucidation of molecular epidemiology and pathophysiology of acquired sideroblastic anemiaPrincipal Investigator
- Principal Investigator
  
  Fujiwara Tohru
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Tohoku University
The role of type 2 innate lymphoid cells in the pulmonary arterial hypertension
- Principal Investigator
  
  Shirota Yuko
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Tohoku Medical and Pharmaceutical University
  Tohoku University
Establishment of in vivo model of anemia by shRNA transgene controlled by erythroid-lineage specific promoterPrincipal Investigator
- Principal Investigator
  
  FUJIWARA TOHRU
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Tohoku University
The role of myeloid derived suppressor cells and transcription factor GATA2 in collagen disease related pulmonary arterial hypertension
- Principal Investigator
  
  Shirota Yuko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Tohoku University
Generation and analysis of in vitro, in vivo model of sideroblastic anemia
- Principal Investigator
  
  Harigae Hideo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Tohoku University
赤芽球におけるＬＭＯ２を介した転写制御機構の解明Principal Investigator
- Principal Investigator
  
  藤原亨
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Contribution of transcriptional corepressor ETO2 to the epigenome formation in erythroblastsPrincipal Investigator
- Principal Investigator
  
  FUJIWARA Tohru
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Molecular biology
- Research Institution
  Tohoku University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2013 2012 2011 Other

All Journal Article Presentation Book Other

[Book] 今日の治療指針2017年度版―私はこうして治療している；鉄欠乏性貧血2017
- Author(s)
  藤原　亨
- Total Pages
  2000
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-15K09447
[Book] 日本臨床：貧血学―最新の動向・治療動向―；鉄芽球性貧血　検査・診断・治療2017
- Author(s)
  藤原　亨
- Total Pages
  644
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-15K09447
[Journal Article] Heme-dependent induction of mitophagy program during differentiation of murine erythroid cells2023
- Author(s)
  Ikeda Masatoshi、Kato Hiroki、Shima Hiroki、Matsumoto Mitsuyo、Furukawa Eijiro、Yan Yan、Liao Ruiqi、Xu Jian、Muto Akihiko、Fujiwara Tohru、Harigae Hideo、Bresnick Emery H.、Igarashi Kazuhiko
- Journal Title
  
  Experimental Hematology
  
  Volume: 118 Pages: 21-30
- DOI
  10.1016/j.exphem.2022.11.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07129, KAKENHI-PROJECT-22H00443, KAKENHI-PROJECT-20K07321, KAKENHI-PROJECT-21K20770, KAKENHI-PROJECT-21K08385, KAKENHI-PROJECT-22K16295, KAKENHI-PROJECT-23K24156
[Journal Article] BRD9 determines the cell fate of hematopoietic stem cells by regulating chromatin state2023
- Author(s)
  Xiao Muran、、、、Yokoyama Akihiko、、、、、Inoue Daichi
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 1-22
- DOI
  10.1038/s41467-023-44081-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0119, KAKENHI-PROJECT-21K08385, KAKENHI-PROJECT-20H03717, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-22H00455, KAKENHI-PROJECT-23K24368
[Journal Article] Unrelated cord blood transplantation for adult-onset EBV-associated T-cell and NK-cell lymphoproliferative disorders2022
- Author(s)
  Onishi Yasushi、Onodera Koichi、Fukuhara Noriko、Kato Hiroki、Ichikawa Satoshi、Fujiwara Tohru、Yokoyama Hisayuki、Yamada-Fujiwara Minami、Harigae Hideo
- Journal Title
  
  International Journal of Hematology
  
  Volume: - Issue: 6 Pages: 873-881
- DOI
  10.1007/s12185-022-03313-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08314, KAKENHI-PROJECT-21K08385
[Journal Article] Elucidation of the Role of FAM210B in Mitochondrial Metabolism and Erythropoiesis2022
- Author(s)
  Suzuki Chie、Fujiwara Tohru、Shima Hiroki、Ono Koya、Saito Kei、Kato Hiroki、Onodera Koichi、Ichikawa Satoshi、Fukuhara Noriko、Onishi Yasushi、Yokoyama Hisayuki、Nakamura Yukio、Igarashi Kazuhiko、Harigae Hideo
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 42 Issue: 12
- DOI
  10.1128/mcb.00143-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08385, KAKENHI-PROJECT-22K16294, KAKENHI-PROJECT-22H00443, KAKENHI-PROJECT-20K07321, KAKENHI-PROJECT-21K20770, KAKENHI-PROJECT-22K16295
[Journal Article] Congenital sideroblastic anemia model due to ALAS2 mutation is susceptible to ferroptosis2022
- Author(s)
  Ono Koya、Fujiwara Tohru、Saito Kei、Nishizawa Hironari、Takahashi Noriyuki、Suzuki Chie、Ochi Tetsuro、Kato Hiroki、Ishii Yusho、Onodera Koichi、Ichikawa Satoshi、Fukuhara Noriko、Onishi Yasushi、Yokoyama Hisayuki、Yamada Rie、Nakamura Yukio、Igarashi Kazuhiko、Harigae Hideo
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 9024-9024
- DOI
  10.1038/s41598-022-12940-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08385, KAKENHI-PROJECT-22K16294, KAKENHI-PROJECT-22H00443, KAKENHI-PROJECT-21K20770, KAKENHI-PROJECT-22K16295
[Journal Article] Exploring the mechanistic link between SF3B1 mutation and ring sideroblast formation in myelodysplastic syndrome2022
- Author(s)
  Ochi Tetsuro、Fujiwara Tohru、Ono Koya、Suzuki Chie、Nikaido Maika、Inoue Daichi、Kato Hiroki、Onodera Koichi、Ichikawa Satoshi、Fukuhara Noriko、Onishi Yasushi、Yokoyama Hisayuki、Nakamura Yukio、Harigae Hideo
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 14562-14562
- DOI
  10.1038/s41598-022-18921-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08385, KAKENHI-PROJECT-22K16294, KAKENHI-PROJECT-21K20770, KAKENHI-PROJECT-20H03717, KAKENHI-PROJECT-22K16295
[Journal Article] Targeting stanniocalcin‐1‐expressing tumor cells elicits efficient antitumor effects in a mouse model of human lung cancer2021
- Author(s)
  Abe Kotaro、Kanehira Masahiko、Ohkouchi Shinya、Kumata Sakiko、Suzuki Yamato、Oishi Hisashi、Noda Masafumi、Sakurada Akira、Miyauchi Eisaku、Fujiwara Tohru、Harigae Hideo、Okada Yoshinori
- Journal Title
  
  Cancer Medicine
  
  Volume: 10 Issue: 9 Pages: 3085-3100
- DOI
  10.1002/cam4.3852
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08167, KAKENHI-PROJECT-18K08314, KAKENHI-PROJECT-18K08136, KAKENHI-PROJECT-19K17624, KAKENHI-PROJECT-21K08385
[Journal Article] Salvage Cord Blood Transplantation for Sustained Remission of Acute Megakaryoblastic Leukemia That Relapsed Early after Myeloablative Transplantation2021
- Author(s)
  Ichikawa Satoshi、Fujiwara Tohru、Saito Kei、Sakurai Kazuki、Inokura Kyoko、Fukuhara Noriko、Yokoyama Hisayuki、Onodera Koichi、Onishi Yasushi、Kameoka Junichi、Harigae Hideo
- Journal Title
  
  Intern. Med.
  
  Volume: 60 Issue: 18 Pages: 3015-3019
- DOI
  10.2169/internalmedicine.6796-20
- NAID
  130008088286
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2021-09-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08314, KAKENHI-PROJECT-21K08385
[Journal Article] A novel case of γδ T cell leukemia with recurrent genetic abnormalities accompanied by agranulocytosis2020
- Author(s)
  Ichikawa Satoshi、Fujiwara Tohru、Saito Kei、Fukuhara Noriko、Yokoyama Hisayuki、Hatta Shunsuke、Onodera Koichi、Onishi Yasushi、Fujishima Fumiyoshi、Ichinohasama Ryo、Harigae Hideo
- Journal Title
  
  Annals of Hematology
  
  Volume: - Issue: 10 Pages: 2665-2668
- DOI
  10.1007/s00277-020-04241-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08314, KAKENHI-PROJECT-18K07435
[Journal Article] Acquisition of monosomy 7 and a RUNX1 mutation in Pearson syndrome2020
- Author(s)
  Nishimura Akira、Hirabayashi Shinsuke、Hasegawa Daisuke、Yoshida Kenichi、Shiraishi Yuichi、Ashiarai Miho、Hosoya Yosuke、Fujiwara Tohru、Harigae Hideo、Miyano Satoru、Ogawa Seishi、Manabe Atsushi
- Journal Title
  
  Pediatric Blood & Cancer
  
  Volume: 68 Issue: 2
- DOI
  10.1002/pbc.28799
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08314, KAKENHI-PROJECT-18K16128, KAKENHI-PROJECT-19H05656
[Journal Article] 環状鉄芽球と鉄代謝2020
- Author(s)
  藤原亨
- Journal Title
  
  臨床血液
  
  Volume: 61 Pages: 770-778
- NAID
  130007884764
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08314
[Journal Article] Generation and Molecular Characterization of Human Ring Sideroblasts: a Key Role of Ferrous Iron in Terminal Erythroid Differentiation and Ring Sideroblast Formation.2019
- Author(s)
  Saito K, Fujiwara T, Hatta S, Morita M, Ono K, Suzuki C, Fukuhara N, Onishi Y, Nakamura Y, Kawamata S, Shimizu R, Yamamoto M, Harigae H.
- Journal Title
  
  Mol Cell Biol.
  
  Volume: 39 Issue: 7
- DOI
  10.1128/mcb.00387-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02507, KAKENHI-PROJECT-18K08314, KAKENHI-PROJECT-17H04668, KAKENHI-PROJECT-19H03555
[Journal Article] Molecular pathophysiology and genetic mutations in congenital sideroblastic anemia2019
- Author(s)
  Fujiwara T, Harigae H
- Journal Title
  
  Free Radic Biol Med
  
  Volume: 133 Pages: 179-185
- DOI
  10.1016/j.freeradbiomed.2018.08.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08314, KAKENHI-PROJECT-17H04668
[Journal Article] Sideroblastic anemia2019
- Author(s)
  Fujiwara T
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 60 Issue: 5 Pages: 408-416
- DOI
  10.11406/rinketsu.60.408
- NAID
  130007659586
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08314
[Journal Article] Study of pathophysiology and molecular characterization of congenital anemia in India using targeted next-generation sequencing approach2019
- Author(s)
  Kedar PS, Harigae H, Ito E, Muramatsu H, Kojima S, Okuno Y, Fujiwara T, Dongerdiye R, Warang PP, Madkaikar MR
- Journal Title
  
  Int J Hematol
  
  Volume: 60 Issue: 5 Pages: 408-416
- DOI
  10.1007/s12185-019-02716-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08314, KAKENHI-PROJECT-18H04039, KAKENHI-PROJECT-17H04668
[Journal Article] Flow Cytometry-Based Photodynamic Diagnosis with 5-Aminolevulinic Acid for the Detection of Minimal Residual Disease in Multiple Myeloma2019
- Author(s)
  Iwaki K, Fujiwara T, Ito T, Suzuki C, Sasaki K, Ono K, Saito K, Fukuhara N, Onishi Y, Yokoyama H, Fujimaki S, Tanaka T, Tamura H, Fujiwara M, Harigae H
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 249 Issue: 1 Pages: 19-28
- DOI
  10.1620/tjem.249.19
- NAID
  130007706214
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08314
[Journal Article] Preemptive therapy for cytomegalovirus reactivation after daratumumab-containing treatment in patients with relapsed and refractory multiple myeloma.2019
- Author(s)
  Nakagawa R, Onishi Y, Kawajiri A, Onodera K, Furukawa E, Sano S, Saito K, Ichikawa S, Fujiwara T, Fukuhara N, Harigae H.
- Journal Title
  
  Ann Hematol.
  
  Volume: - Issue: 8 Pages: 1999-2001
- DOI
  10.1007/s00277-019-03645-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07435, KAKENHI-PROJECT-17K16175, KAKENHI-PROJECT-18K08314
[Journal Article] A defined culture method enabling the establishment of ring sideroblasts from induced pluripotent cells of X-linked sideroblastic anemia.2018
- Author(s)
  1.Hatta S, Fujiwara T, Yamamoto T, Saito K, Kamata M, Tamai Y, Kawamata S, Harigae H.
- Journal Title
  
  Haematologica.
  
  Volume: - Issue: 5 Pages: 188-191
- DOI
  10.3324/haematol.2017.179770
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04668, KAKENHI-PROJECT-15K09447, KAKENHI-PROJECT-16K19564, KAKENHI-PROJECT-18K08314
[Journal Article] Infection perturbs Bach2- and Bach1-dependent erythroid lineage chioce to cause anemia2018
- Author(s)
  Kato H, Itoh-Nakadai A, Matsumoto M, Ishii Y, Watanabe-Matsui M, Ikeda M, Ebina-Shibuya R, Sato Y, Kobayashi M, Nishizawa H, Suzuki K, Muto A, Fujiwara T, Nannya Y, Cazzola M, Ogawa S, Harigae H, Igarashi K
- Journal Title
  
  Nat Immunol
  
  Volume: 19 Issue: 10 Pages: 496-497
- DOI
  10.1038/s41590-018-0202-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08314, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-16K07108, KAKENHI-PROJECT-16J40189, KAKENHI-PROJECT-16K08572
[Journal Article] Establishment of a Screening System to Identify Novel GATA-2 Transcriptional Regulators2018
- Author(s)
  Ohashi K, Fujiwara T, Onodera K, Saito Y, Ichikawa S, Kobayashi M, Okitsu Y, Fukuhara N, Onishi Y, Harigae H.
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 244 Issue: 1 Pages: 41-52
- DOI
  10.1620/tjem.244.41
- NAID
  130006315364
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09819, KAKENHI-PROJECT-17K16175, KAKENHI-PROJECT-17K16176, KAKENHI-PROJECT-15K09447
[Journal Article] Molecular pathophysiology of sideroblastic anemia2018
- Author(s)
  Fujiwara T
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 59 Issue: 10 Pages: 1979-1987
- DOI
  10.11406/rinketsu.59.1979
- NAID
  130007496828
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08314
[Journal Article] Five-aminolevulinic acid: New Approach for Congenital Sideroblastic Anemia2018
- Author(s)
  Ishida H, Imamura T, Morimoto A, Fujiwara T, Harigae H
- Journal Title
  
  Pediatr Int
  
  Volume: 60 Issue: 5 Pages: 496-497
- DOI
  10.1111/ped.13558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08314, KAKENHI-PROJECT-17H04668
[Journal Article] GATA Transcription Factors: Basic Principles and Related Human Disorders2017
- Author(s)
  Fujiwara T
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 242 Issue: 2 Pages: 83-91
- DOI
  10.1620/tjem.242.83
- NAID
  130006776940
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09447
[Journal Article] Effects of in vivo deletion of GATA2 in bone marrow stromal cells2017
- Author(s)
  Hasegawa S, Fujiwara T, Okitsu Y, Kato H, Sato Y, Fukuhara N, Onishi Y, Shimizu R, Yamamoto M, Harigae H.
- Journal Title
  
  Experimental Hematology
  
  Volume: 56 Pages: 31-45
- DOI
  10.1016/j.exphem.2017.08.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09819, KAKENHI-PROJECT-15K09447
[Journal Article] Impact of TET2 deficiency on iron metabolism in erythroblasts.2017
- Author(s)
  Inokura K, Fujiwara T, Saito K, Iino T, Hatta S, Okitsu Y, Fukuhara N, Onishi Y, Ishizawa K, Shimoda K, Harigae H
- Journal Title
  
  Exp Hematol.
  
  Volume: - Pages: 56-67
- DOI
  10.1016/j.exphem.2017.01.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293225, KAKENHI-PROJECT-15K09447, KAKENHI-PROJECT-16K09819, KAKENHI-PROJECT-16K19564, KAKENHI-PROJECT-17H04210
[Journal Article] A novel heterozygous ALAS2 mutation in a female with macrocytic sideroblastic anemia resembling myelodysplastic syndrome with ring sideroblasts: a case report and literature review2017
- Author(s)
  Fujiwara T, Fukuhara N, Ichikawa S, Kobayashi M, Okitsu Y, Onishi Y, Furuyama K, Harigae H
- Journal Title
  
  Annals of Hematology
  
  Volume: 96(11) Issue: 11 Pages: 1955-1957
- DOI
  10.1007/s00277-017-3106-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09819, KAKENHI-PROJECT-17K08640, KAKENHI-PROJECT-17K16176, KAKENHI-PROJECT-17H04668, KAKENHI-PROJECT-15K09447
[Journal Article] Forced FOG1 expression in erythroleukemia cells: Induction of erythroid genes and repression of myelo-lymphoid transcription factor PU.1.2017
- Author(s)
  Fujiwara T, Sasaki K, Saito K, Hatta S, Ichikawa S, Kobayashi M, Okitsu Y, Fukuhara N, Onishi Y, Harigae H.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 485 Issue: 2 Pages: 380-387
- DOI
  10.1016/j.bbrc.2017.02.068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293225, KAKENHI-PROJECT-16K19564, KAKENHI-PROJECT-16K09819, KAKENHI-PROJECT-15K09447
[Journal Article] Dynamics of absorption, metabolism, and excretion of 5-aminolevulinic acid in human intestinal Caco-2 cells.2017
- Author(s)
  Saito K, Fujiwara T, Ota U, Hatta S, Ichikawa S, Kobayashi M, Okitsu Y, Fukuhara N, Onishi Y, Ishizuka M, Tanaka T, Harigae H
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 11 Pages: 105-111
- DOI
  10.1016/j.bbrep.2017.07.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09819, KAKENHI-PROJECT-17K16176, KAKENHI-PROJECT-17H04668, KAKENHI-PROJECT-15K09447, KAKENHI-PROJECT-16K15324, KAKENHI-PROJECT-16K19564
[Journal Article] An Lysophosphatidic Acid Receptors 1 and 3 Axis Governs Cellular Senescence of Mesenchymal Stromal Cells and Promotes Growth and Vascularization of Multiple Myeloma.2017
- Author(s)
  Kanehira M, Fujiwara T, Nakajima S, Okitsu Y, Onishi Y, Fukuhara N, Ichinohasama R, Okada Y, Harigae H.
- Journal Title
  
  Stem Cells.
  
  Volume: 35 Issue: 3 Pages: 739-753
- DOI
  10.1002/stem.2499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08609, KAKENHI-PROJECT-15K09447, KAKENHI-PROJECT-15K09465, KAKENHI-PROJECT-16K09819
[Journal Article] Iron-heme-Bach1 axis is involved in erythroblast adaptation to iron deficiency.2017
- Author(s)
  Kobayashi M, Kato H, Hada H, Itoh-Nakadai A, Fujiwara T, Muto A, Inoguchi Y, Ichiyanagi K, Hojo W, Tomosugi N, Sasaki H, Harigae H, Igarashi K.
- Journal Title
  
  Haematologica
  
  Volume: 102 Issue: 3 Pages: 454-465
- DOI
  10.3324/haematol.2016.151043
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293225, KAKENHI-PROJECT-16K08572, KAKENHI-PROJECT-15H02506
[Journal Article] Identification of a novel putative mitochondrial protein FAM210B associated with erythroid differentiation.2016
- Author(s)
  Kondo A, Fujiwara T, Okitsu Y, Fukuhara N, Onishi Y, Nakamura Y, Sawada K, Harigae H.
- Journal Title
  
  International Journal of Hematology
  
  Volume: 未定
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09447
[Journal Article] Inhibition of human primary megakaryocyte differentiation by anagrelide: a gene expression profiling analysis.2016
- Author(s)
  Sakurai K, Fujiwara T, Hasegawa S, Okitsu Y, Fukuhara N, Onishi Y, Yamada-Fujiwara M, Ichinohasama R, Harigae H.
- Journal Title
  
  Int J Hematol.
  
  Volume: 104 Issue: 2 Pages: 190-199
- DOI
  10.1007/s12185-016-2006-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08609, KAKENHI-PROJECT-15K09447
[Journal Article] Identification of a novel putative mitochondrial protein FAM210B associated with erythroid differentiation.2016
- Author(s)
  Kondo A, Fujiwara T, Okitsu Y, Fukuhara N, Onishi Y, Nakamura Y, Sawada K, Harigae H.
- Journal Title
  
  Int J Hematol.
  
  Volume: 103 Issue: 4 Pages: 387-395
- DOI
  10.1007/s12185-016-1968-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293225, KAKENHI-PROJECT-15K09447, KAKENHI-PROJECT-16K09819
[Journal Article] GATA2 regulates dendritic cell differentiation.2016
- Author(s)
  Onodera K, Fujiwara T, Onishi Y, Itoh-Nakadai A, Okitsu Y, Fukuhara N, Ishizawa K, Shimizu R, Yamamoto M, Harigae H.
- Journal Title
  
  Blood
  
  Volume: 128 Issue: 4 Pages: 508-518
- DOI
  10.1182/blood-2016-02-698118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04759, KAKENHI-PROJECT-26860716, KAKENHI-PROJECT-15K08609, KAKENHI-PROJECT-15K09447, KAKENHI-PROJECT-16K09819
[Journal Article] Role of transcriptional corepressor ETO2 in erythroid cells2013
- Author(s)
  Fujiwara T, Alqadi YW, Okitsu Y, Fukuhara N, Onishi Y, Ishizawa K, Harigae H
- Journal Title
  
  Experimental Hematology
  
  Volume: 41 Issue: 3 Pages: 303-315
- DOI
  10.1016/j.exphem.2012.10.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23687024, KAKENHI-PROJECT-23791067, KAKENHI-PUBLICLY-23118502
[Journal Article] Gene Expression Profiling Identifies HOXB4 as a Direct Downstream Target of GATA-2 in Human CD34+ Hematopoietic Cells2012
- Author(s)
  Fujiwara T, Yokoyama H, Okitsu Y, Kamata M, Fukuhara N, Onishi Y, Fujimaki S, Takahashi S, Ishizawa K, Bresnick E and Harigae H
- Journal Title
  
  PLoS ONE
  
  Volume: 7 Issue: 9 Pages: e40959-e40959
- DOI
  10.1371/journal.pone.0040959
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590687, KAKENHI-PROJECT-23687024, KAKENHI-PROJECT-23791067, KAKENHI-PUBLICLY-23118502
[Journal Article] Genome-wide analysis of GATA transcription factor in hematopoietic cells2012
- Author(s)
  Fujiwara T
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 53 Issue: 3 Pages: 287-294
- DOI
  10.11406/rinketsu.53.287
- NAID
  130004501644
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23687024
[Presentation] Mitochondrial metabolism and erythroid differentiation2023
- Author(s)
  Fujiwara T, Suzuki C, Harigae H
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08385
[Presentation] ヒト赤芽球細胞株を用いた造血性プロトポルフィリン症の病態解明2023
- Author(s)
  二階堂舞香, 藤原亨, 鈴木千恵, 小野浩弥, 加藤浩貴, 小野寺晃一, 市川聡, 福原規子, 大西康, 横山寿行, 中村幸夫, 張替秀郎
- Organizer
  第47回日本鉄バイオサイエンス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08385
[Presentation] Roles for heme synthesis in the maintenance of hematopoietic stem and progenitor cells2023
- Author(s)
  Yan Y, Kato H, Sano S, Furukawa E, Michimata D, Tanaka Y, Sakurai K, Onodera K, Ichikawa S, Fujiwara T, Onishi Y, Fukuhara N, Yokoyama H, Harigae H
- Organizer
  The 13th Japanese Society of Hematology International Meeting
- Data Source
  KAKENHI-PROJECT-21K08385
[Presentation] Transcription factor GATA2 is inevitable for the survival and proper differentiation of thymic multipotent progenitor cells by gene expression orchestration2023
- Author(s)
  Sano S, Kato H, Yan Y, Furukawa E, Michimata D, Tanaka Y, Sakurai K, Onodera K, Ichikawa S, Fukuhara N, Onishi Y, Yokoyama H, Fujiwara T, Harigae H
- Organizer
  The 65th American Society of Hematology
- Data Source
  KAKENHI-PROJECT-21K08385
[Presentation] Comparison of VWF:RCo/VWF:Ag ratios with the VWF large multimer indices in patients with aortic stenosis2023
- Author(s)
  Horiuchi H, Okubo N, Sugawara S, Fujiwara T, Eura Y, Kokame K, Hayakawa M, Matsumoto M, Kawate Y, Fujimaki S
- Organizer
  The International Society on Thrombosis and Haemostasis 2023 Congress
- Data Source
  KAKENHI-PROJECT-21K08385
[Presentation] 鉄代謝異常と貧血2023
- Author(s)
  藤原　亨
- Organizer
  第123回日本輸血・細胞治療学会東北支部例会
- Data Source
  KAKENHI-PROJECT-21K08385
[Presentation] 鉄代謝異常に伴う貧血の病態と検査への応用2023
- Author(s)
  藤原　亨
- Organizer
  第70回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08385
[Presentation] Roles for heme synthesis in the maintenance of hematopoietic stem and progenitor cells2023
- Author(s)
  Yan Y, Kato H, Sano S, Furukawa E, Michimata D, Tanaka Y, Sakurai K, Onodera K, Ichikawa S, Fujiwara T, Onishi Y, Fukuhara N, Yokoyama H, Harigae H
- Organizer
  The 65th American Society of Hematology
- Data Source
  KAKENHI-PROJECT-21K08385
[Presentation] Hematopoietic stem/progenitor cell intrinsic SAM synthesis is required to prevent p53 pathway activation by maintaining DNA stability2023
- Author(s)
  Furukawa E, Kato H, Sano S, Yan Y, Michimata D, Tanaka Y, Sakurai K, Onodera K, Ichikawa S, Fukuhara N, Onishi Y, Yokoyama H, Saegusa D, Fujiwara T, Igarashi K, Harigae H
- Organizer
  The 65th American Society of Hematology
- Data Source
  KAKENHI-PROJECT-21K08385
[Presentation] 赤血球ヘム合成系とその異常2023
- Author(s)
  藤原　亨
- Organizer
  第47回日本鉄バイオサイエンス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08385
[Presentation] Altered transcription by GATA1 impairs autophagy and prevents ferroptosis in X-linked sideroblastic anemia2022
- Author(s)
  Ono K, Fujiwara T, Shima H, Suzuki C, Takahashi N, Nishizawa H, Onodera K, Ichikawa S, Fukuhara N, Onishi Y, Hisayuki Y, Fujimaki S, Nakamura Y, Igarashi K, Harigae H
- Organizer
  第64回米国血液学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08385
[Presentation] Impact of FECH deficiency on ring sideroblast formation in erythroblasts2022
- Author(s)
  Nikaido M, Fujiwara T, Suzuki C, Ono K, Kato H, Onodera K, Ichikawa S, Fukuhara N, Onishi Y, Yokoyama H, Nakamura Y, Harigae H
- Organizer
  第84回日本血液学会
- Data Source
  KAKENHI-PROJECT-21K08385
[Presentation] Exploring the mechanistic link between SF3B1 mutation and ring sideroblast formation in MDS2022
- Author(s)
  Ochi T, Fujiwara T, Ono K, Suzuki C, Inoue D, Kato H, Onodera K, Ichikawa S, Fukuhara N, Onishi Y, Yokoyama H, Nakamura Y, Harigae H
- Organizer
  第84回日本血液学会
- Data Source
  KAKENHI-PROJECT-21K08385
[Presentation] Integration of erythroid differentiation and autophagy by iron-heme metabolism2022
- Author(s)
  Igarashi K, Kato H, Ikeda M, Fujiwara T, Harigae H
- Organizer
  第84回日本血液学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K08385
[Presentation] FOG1-dependent transcriptional network involves glucose metabolic regulation of erythroid cells.2021
- Author(s)
  Fujiwara T, Suzuki C, Ono K, Saito K, Kato H, Onodera K, Ichikawa S, Fukuhara N, Onishi Y, Yokoyama H, Harigae H.
- Organizer
  第83回日本血液学会
- Data Source
  KAKENHI-PROJECT-18K08314
[Presentation] Elucidation of the role of FAM210B in mitochondrial metabolism in erythroblasts.2021
- Author(s)
  Suzuki C, Fujiwara T, Shima H, Ono K, Saito K, Kato H, Onodera K, Ichikawa S, Fukuhara N, Onishi Y, Yokoyama H, Nakamura Y, Harigae H.
- Organizer
  第83回日本血液学会
- Data Source
  KAKENHI-PROJECT-21K08385
[Presentation] FOG1-dependent transcriptional network involves glucose metabolic regulation of erythroid cells.2021
- Author(s)
  Fujiwara T, Suzuki C, Ono K, Saito K, Kato H, Onodera K, Ichikawa S, Fukuhara N, Onishi Y, Yokoyama H, Harigae H.
- Organizer
  第83回日本血液学会
- Data Source
  KAKENHI-PROJECT-21K08385
[Presentation] Inhibition of S-Adenosylmethionine synthesis promotes erythropoiesis via epigenetic modifications.2021
- Author(s)
  Kato H, Long NC, Ishii Y, Matsumoto M, Rhee C, Saigusa D, Funayama R, Okae H, Fujiwara T, Muto A, Harigae H, Scadden DT, Igarashi K.
- Organizer
  第63回米国血液学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08385
[Presentation] Monitoring CAR-T cells using flow cytometry: A feasibility study.2021
- Author(s)
  Fujiwara T, Onishi Y, Niizuma H, Okubo N, Sugawara S, Moriya K, Ichikawa S, Irie M, Fukuhara N, Yokoyama H, Fujiwara M, Fujimaki S, Sasahara Y, Harigae H.
- Organizer
  第12回日本血液学会国際シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08385
[Presentation] Cellular models of X-linked sideroblastic anemia based on immortalized human erythroid progenitors.2021
- Author(s)
  Ono K, Fujiwara T, Saito K, Suzuki C, Takahashi N, Kato H, Onodera K, Ichikawa S, Fukuhara N, Onishi Y, Yokoyama H, Nakamura Y, Harigae H.
- Organizer
  第83回日本血液学会
- Data Source
  KAKENHI-PROJECT-21K08385
[Presentation] Inhibition of S-Adenosylmethionine synthesis promotes erythropoiesis via epigenetic modifications.2021
- Author(s)
  Kato H, Long NC, Ishii Y, Matsumoto M, Rhee C, Saigusa D, Funayama R, Okae H, Fujiwara T, Muto A, Harigae H, Scadden DT, Igarashi K.
- Organizer
  第63回米奥血液学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08314
[Presentation] Methionine metabolism controls erythropoiesis by epigenetic regulation.2021
- Author(s)
  Kato H, Long NC, Ishii Y, Matsumoto M, Mitsueda D, Funayama R, Okae H, Fujiwara T, Muto A, Nakayama K, Arima T, Scadden D, Igarashi K, Harigae H.
- Organizer
  第83回日本血液学会
- Data Source
  KAKENHI-PROJECT-21K08385
[Presentation] Monitoring CAR-T cells using flow cytometry: A feasibility study.2021
- Author(s)
  Fujiwara T, Onishi Y, Niizuma H, Okubo N, Sugawara S, Moriya K, Ichikawa S, Irie M, Fukuhara N, Yokoyama H, Fujiwara M, Fujimaki S, Sasahara Y, Harigae H.
- Organizer
  第12回日本血液学会国際シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08314
[Presentation] Cellular models of X-linked sideroblastic anemia based on immortalized human erythroid progenitors.2021
- Author(s)
  Ono K, Fujiwara T, Saito K, Suzuki C, Takahashi N, Kato H, Onodera K, Ichikawa S, Fukuhara N, Onishi Y, Yokoyama H, Nakamura Y, Harigae H.
- Organizer
  第83回日本血液学会
- Data Source
  KAKENHI-PROJECT-18K08314
[Presentation] FOG1-DEPENDENT TRANSCRIPTIONAL NETWORK INVOLVES GLUCOSE METABOLIC REGULATION OF ERYTHROID CELLS.2020
- Author(s)
  Fujiwara T, Suzuki C, Sasaki K, Sano S, Ono K, Saito K, Onodera K, Ichikawa S, Fukuhara N, Onishi Y, Hisayuki Y, Harigae H.
- Organizer
  第25回欧州血液学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08314
[Presentation] TRANSCRIPTIONAL REGULATION OF FERROPTOSIS IN X-LINKED SIDEROBLASTIC ANEMIA.2020
- Author(s)
  Ono K, Fujiwara T, Saito K, Suzuki C, Takahashi N, Yan Y, Onodera K, Ichikawa S, Fukuhara N, Onishi Y, Hisayuki Y, Fujimaki S, Nakamura Y, Harigae H.
- Organizer
  第62回米国血液学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08314
[Presentation] Establishment of congenital sideroblastic anemia model due to ABCB7 defect.2020
- Author(s)
  Fujiwara T, Ochi T, Suzuki C, Ono K, Saito K, Fukuhara N, Onishi Y, Yokoyama H, Nakamura Y, Harigae H.
- Organizer
  第82回日本血液学会総会
- Data Source
  KAKENHI-PROJECT-18K08314
[Presentation] Impact of ferroptosis in X-linked sideroblastic anemia.2020
- Author(s)
  Ono K, Fujiwara T, Saito K, Suzuki C, Takahshi N, Yan Y, Onodera K, Ichikawa S, Fukuhara N, Onishi Y, Yokoyama H, Nakamura Y, Harigae H.
- Organizer
  第82回日本血液学会総会
- Data Source
  KAKENHI-PROJECT-18K08314
[Presentation] ROLE OF FERROPTOSIS IN X-LINKED SIDEROBLASTIC ANEMIA.2020
- Author(s)
  Ono K, Fujiwara T, Saito K, Suzuki C, Takahashi N, Yan Y, Onodera K, Ichikawa S, Fukuhara N, Onishi Y, Hisayuki Y, Fujimaki S, Nakamura Y, Harigae H.
- Organizer
  第25回欧州血液学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08314
[Presentation] Characterization of congenital sideroblastic anemia model due to ABCB7 defects: How do defects in iron-sulfur cluster metabolism lead to ring sideroblast formation?2019
- Author(s)
  Fujiwara T, Suzuki C, Ochi T, Ono K, Saito K, Fukuhara N, Onishi Y, Hisayuki Y, Fujimaki S, Nakamura Y, Harigae H
- Organizer
  The 61th American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08314
[Presentation] Proteomic analysis of mitochondrial membrane protein FAM210B in erythroid cells2019
- Author(s)
  Suzuki C, Fujiwara T, Shima H, Saito K, Ono K, Fukuhara N, Onishi Y, Hisayuki Y, Fujimaki S, Nakamura Y, Harigae H
- Organizer
  The 61th American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08314
[Presentation] Molecular Characterization and Novel Therapeutic Strategy for X-linked Sideroblastic Anemia Associated with ALAS2 Missense Variants2019
- Author(s)
  Ono K, Fujiwara T, Saito K, Suzuki C, Takahashi N, Onodera K, Ichikawa S, Fukuhara N, Onishi Y, Hisayuki Y, Nakamura Y, Harigae H
- Organizer
  The 61th American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08314
[Presentation] EPIDEMIOLOGY AND MOLECULAR CHARACTERIZATION OF CONGENITAL SIDEROBLASTIC ANEMIA2019
- Author(s)
  Fujiwara T, Saito K, Suzuki C, Ono K, Fukuhara N, Onishi Y, Nakamura Y, Harigae H
- Organizer
  The 8th International Bioiron Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08314
[Presentation] Ring sideroblast and iron metabolism2019
- Author(s)
  Fujiwara T
- Organizer
  The 81th Annual Meeting of the Japanese Society of Hematology
- Invited
- Data Source
  KAKENHI-PROJECT-18K08314
[Presentation] Generation and molecular characterization of human ring sideroblasts2018
- Author(s)
  1.Saito K, Fujiwara T, Hatta S, Okitsu Y, Fukuhara N, Onishi Y, Nakamura Y, Harigae H
- Organizer
  The 60th American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08314
[Presentation] Cyclosporine A treatment for T-cell large granular lymphocyteic leukemia: a single-center experience2018
- Author(s)
  Onishi Y, Fujiwara M, Sano S, Nakagawa R, Kawajiri A, Saito K, Onodera K, Ichikawa S, Fukuhara N, Fujiwara T, Harigae H
- Organizer
  第80回日本血液学会総会
- Data Source
  KAKENHI-PROJECT-18K08314
[Presentation] 鉄芽球性貧血の分子病態2018
- Author(s)
  藤原　亨
- Organizer
  第80回日本血液学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08314
[Presentation] Characterization of in vitro model of X-linked sideroblastic anemia2018
- Author(s)
  Saito K, Fujiwara T, Hatta S, Onodera K, Ichikawa S, Fukuhara N, Onishi Y, Nakamura Y, Harigae H
- Organizer
  第80回日本血液学会総会
- Data Source
  KAKENHI-PROJECT-18K08314
[Presentation] Establishment of a screening system to identify novel GATA-2 transcriptional regulators2018
- Author(s)
  Ohashi K, Fujiwara T, Onodera K, Saito Y, Ichikawa S, Kobayashi M, Okitsu Y, Fukuhara N, Onishi Y, Harigae H
- Organizer
  第80回日本血液学会総会
- Data Source
  KAKENHI-PROJECT-18K08314
[Presentation] Exploring the mechanism of FOG1-dependent transcriptional regulation in erythroid cells2017
- Author(s)
  Tohru Fujiwara, Katsuyuki Sasaki, Kei Saito, Shunsuke Hatta, Satoshi Ichikawa, Masahiro Kobayashi, Yoko Okitsu, Noriko Fukuhara, Yasushi Onishi, Hideo Harigae
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09447
[Presentation] Exploring the Mechanism of Fog1-Dependent Transcriptional Regulation in Erythroid Cells2017
- Author(s)
  Tohru Fujiwara, Katsuyuki Sasaki, Kei Saito, Shunsuke Hatta, Satoshi Ichikawa, Masahiro Kobayashi, Yoko Okitsu, Noriko Fukuhara, Yasushi Onishi, Hideo Harigae
- Organizer
  European Hematology Association 22nd Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09447
[Presentation] ALAS2遺伝子変異を認めた大球性鉄芽球性貧血の一例2017
- Author(s)
  藤原亨、福原規子、猪俣美津恵、大西康、古山和道、張替秀郎
- Organizer
  第41回日本鉄バイオサイエンス学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09447
[Presentation] Generation of Induced Pluripotent Stem Cell-Derived Erythroblasts From A Patient With X-Linked Sideroblastic Anemia2017
- Author(s)
  Shunsuke Hatta, Tohru Fujiwara, Takako Yamamoto, Mayumi Kamata, Yoshiko Tamai, Yukiko Nakamura, Shin Kameoka, Hideo Harigae
- Organizer
  Seventh Congress of the International Biolron Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09447
[Presentation] 第78回日本血液学会2016
- Author(s)
  Saito K, Inokura K, Fujiwara T, Hatta S, Okitsu Y, Fukuhara N, Onishi Y, Ishizawa K, Shimoda K, Harigae H
- Organizer
  第78回日本血液学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K09447
[Presentation] Impact of TET2 on iron metabolism in erythroblasts:A potential link to ring sidero formation2016
- Author(s)
  斎藤慧、猪倉恭子、藤原亨、八田俊介、沖津庸子、福原規子、大西康、石澤賢一、下田和哉、張替秀郎
- Organizer
  日本血液学会
- Place of Presentation
  パシフィコ横浜・横浜市
- Data Source
  KAKENHI-PROJECT-26293225
[Presentation] Identification of a novel mitochondorial protein FAM210B associated with erythroid differentiation2016
- Author(s)
  近藤愛子、藤原亨、沖津庸子、福原規子、大西康、中村幸夫、澤田賢一、張替秀郎
- Organizer
  日本血液学会
- Place of Presentation
  パシフィコ横浜・横浜市
- Data Source
  KAKENHI-PROJECT-26293225
[Presentation] 腸管上皮細胞モデルにおけるALAの代謝2016
- Author(s)
  斎藤慧、藤原亨、田中徹、張替秀郎
- Organizer
  日本鉄バイオサイエンス学会
- Place of Presentation
  名古屋大学豊田講堂・名古屋市
- Data Source
  KAKENHI-PROJECT-26293225
[Presentation] Identification of a novel putative mitochondrial protein FAM210B associated with erythroid differentiation.2016
- Author(s)
  Kondo A, Fujiwara T, Okitsu Y, Fukuhara N, Onishi Y, Nakamura Y, Sawada K, Harigae H
- Organizer
  第78回日本血液学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K09447
[Presentation] Generation of induced pluripotent stem cell-derived erythroblasts from a patient with X-linked sideroblastic anemia.2016
- Author(s)
  Hatta S, Fujiwara T, Yamamoto T, Kamata M, Tamai Y, Nakamura Y, Kawamata S, Harigae H
- Organizer
  第58回米国血液学会
- Place of Presentation
  サンディエゴ, アメリカ
- Year and Date
  2016-12-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09447
[Presentation] Generation of Induced Pluripotent Stem Cell-Derived Erythroblasts from a Patient with X-Linked Sideroblastic Anemia2016
- Author(s)
  Shunsuke Hatta,Tohru Fujiwara, Takako Yamamoto, Mayumi Kamata, Yoshiko Tamai, Yukio Nakamura, Shin Kawamata, Hideo Harigae
- Organizer
  58th Annual Meeting of American Sciety of Hematology
- Place of Presentation
  SanDiego convention center　サンディエゴ・米国
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293225
[Presentation] Transcriptional regulation of erythropoiesis.2016
- Author(s)
  Fujiwara T
- Organizer
  第78回日本血液学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-13
- Invited
- Data Source
  KAKENHI-PROJECT-15K09447
[Presentation] Transcription Factor Bach1 and Bach2 Operate Erythro-myeloid Competitive Differentiation by Responding to Environmental Changes.2016
- Author(s)
  Kato H, Itoh-Nakadai A, Matsumoto M, Ebina-Shibuya R, Sato Y, Kobayashi M, Muto A, Fujiwara T, Harigae H, Igarashi K
- Organizer
  第58回米国血液学会
- Place of Presentation
  サンディエゴ, アメリカ
- Year and Date
  2016-12-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09447
[Presentation] 遺伝性鉄芽球性貧血の疫学と分子病態2015
- Author(s)
  藤原亨、張替秀郎
- Organizer
  第39回日本鉄バイオサイエンス学会学術集会
- Place of Presentation
  岡山コンベンションセンター(岡山市）
- Year and Date
  2015-08-29
- Invited
- Data Source
  KAKENHI-PROJECT-26293225
[Presentation] Regulation of erythropoiesis by histone methyltransferase EZH2 inhibitor 3-Deazaneplanocin A (DZNep)2012
- Author(s)
  Fujiwara T, Saitoh H, Okitsu Y, Fukuhara N, Onishi Y, Ishizawa K, Ichinohasama R, Harigae H
- Organizer
  米国血液学会
- Place of Presentation
  アトランタ(米国)
- Year and Date
  2012-12-08
- Data Source
  KAKENHI-PROJECT-23687024
[Presentation] Elucidation of the role of LMO2 (LIM-only protein 2) in erythroid cells2012
- Author(s)
  Ai Inoue, Tohru Fujiwara et al.
- Organizer
  米国血液学会
- Place of Presentation
  アトランタ（米国）
- Year and Date
  2012-12-07
- Data Source
  KAKENHI-PUBLICLY-23118502
[Presentation] Role of ETO2 in the epigenetic regulation of erythroid genes2011
- Author(s)
  Fujiwara T, Wael YA, Harigae H
- Organizer
  欧州血液学会
- Place of Presentation
  ロンドン(英国)
- Year and Date
  2011-06-11
- Data Source
  KAKENHI-PROJECT-23687024
[Presentation] Expression profiling of ETO2-regulated genes in erythroid cells2011
- Author(s)
  Yarob Wael Alquadi, Tohru Fujiwara, et al
- Organizer
  第73回日本血液学会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-16
- Data Source
  KAKENHI-PROJECT-23687024
[Presentation] Exploring the mechanism of ETO2-dependent transcriptional regulation in erythroid cells2011
- Author(s)
  Wael YA, Fujiwara T, Okitsu Y, Yasushi O, Ishizawa K, Harigae H
- Organizer
  米国血液学会
- Place of Presentation
  サンディエゴ(米国)
- Year and Date
  2011-12-11
- Data Source
  KAKENHI-PROJECT-23687024
[Presentation] Expression profiling ofETO2-regulated genes in erythroid cells2011
- Author(s)
  Wael YA, Fujiwara T, Okitsu Y, Kohata K, Fukuhara N, Yasushi O, Yamamoto J, Ishizawa K, Harigae H
- Organizer
  日本血液学会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-16
- Data Source
  KAKENHI-PROJECT-23687024
[Presentation] Exploring the mechanism of ETO2-dependent transcriptional regulation in erythroid cells2011
- Author(s)
  Yarob Wael Alquadi, Tohru Fujiwara, et al
- Organizer
  米国血液学会
- Place of Presentation
  米国・サンディエゴ
- Year and Date
  2011-12-12
- Data Source
  KAKENHI-PROJECT-23687024
[Presentation] Exploring potential usefulness of 5-aminolevulinic acid for X-linked sideroblastic anemia
- Author(s)
  Fujiwara T, Okamoto K, Niikuni R, Takahashi K, Okitsu Y, Fukuhara N, Onishi Y, Ishizawa K, Ichinohasama R, Nakamura Y, Nakajima M, Tanaka T, Harigae H
- Organizer
  第56回アメリカ血液学会
- Place of Presentation
  サンフランシスコ(米国)
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-26293225
[Presentation] Exploring the potential usefulness of 5-aminolevulinic acid (ALA) for sideroblastic anemia
- Author(s)
  Nikuni R, Fujiwara T, Okitsu Y, Fukuhara N, Onishi Y, Ishizawa K, Ichinohasama R, Tanaka T, Harigae H
- Organizer
  第76回日本血液学会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-26293225
[Presentation] Impact of TET2 deficiency on iron metabolism in erythropoiesis:a potential link to ring sideroblast formation
- Author(s)
  Inokura K, Fujiwara T, Okitsu Y, Fukuhara N, Onishi Y, Ishizawa K, Shimoda K, Harigae H
- Organizer
  第56回アメリカ血液学会
- Place of Presentation
  サンフランシスコ(米国)
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-26293225
[Presentation] 鉄芽球性貧血に対するALAの有用性の基礎的検討
- Author(s)
  藤原亨、新國僚祐、田中徹、張替秀郎
- Organizer
  第38回日本鉄バイオサイエンス学会学術集会
- Place of Presentation
  仙台国際センター(仙台市)
- Year and Date
  2014-09-06 – 2014-09-07
- Data Source
  KAKENHI-PROJECT-26293225
[Presentation] TET2遺伝子の鉄芽球性貧血発症への関与
- Author(s)
  猪倉恭子、藤原亨、下田和哉、張替秀郎
- Organizer
  第38回日本鉄バイオサイエンス学会学術集会
- Place of Presentation
  仙台国際センター(仙台市)
- Year and Date
  2014-09-06 – 2014-09-07
- Data Source
  KAKENHI-PROJECT-26293225
[]
[]

1. Shirota Yuko (20455819)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 石井智徳 (10282138)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 藤井博司 (30531321)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Harigae Hideo (50302146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
5. KAWAMATA Shin (00360842)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. SUZUKI Mikiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. ICHINOHASAMA Ryo

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. YOSHIDA Hitoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. OKITSU Yoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
10. 山本雅之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 兼平雅彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 大河内眞也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 武藤哲彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 福原規子

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
15. 高橋伸一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 清水律子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fujiwara Tohru 藤原 亨

FUJIWARA Tohru 藤原 亨

Research Projects

Research Products

Co-Researchers

転写因子GATA-2を介した造血幹細胞と造血微小環境の機能的連関の解明Principal Investigator

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Elucidation of molecular epidemiology and pathophysiology of acquired sideroblastic anemiaPrincipal Investigator

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The role of type 2 innate lymphoid cells in the pulmonary arterial hypertension

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Establishment of in vivo model of anemia by shRNA transgene controlled by erythroid-lineage specific promoterPrincipal Investigator

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The role of myeloid derived suppressor cells and transcription factor GATA2 in collagen disease related pulmonary arterial hypertension

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Generation and analysis of in vitro, in vivo model of sideroblastic anemia

Principal Investigator

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赤芽球におけるＬＭＯ２を介した転写制御機構の解明Principal Investigator

Principal Investigator

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Contribution of transcriptional corepressor ETO2 to the epigenome formation in erythroblastsPrincipal Investigator

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[Book] 今日の治療指針2017年度版―私はこうして治療している；鉄欠乏性貧血2017

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[Book] 日本臨床：貧血学―最新の動向・治療動向―；鉄芽球性貧血 検査・診断・治療2017

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[Journal Article] Heme-dependent induction of mitophagy program during differentiation of murine erythroid cells2023

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[Journal Article] BRD9 determines the cell fate of hematopoietic stem cells by regulating chromatin state2023

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[Journal Article] Unrelated cord blood transplantation for adult-onset EBV-associated T-cell and NK-cell lymphoproliferative disorders2022

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[Journal Article] Elucidation of the Role of FAM210B in Mitochondrial Metabolism and Erythropoiesis2022

Author(s)

Fujiwara Tohru 藤原亨

FUJIWARA Tohru 藤原亨

[Book] 日本臨床：貧血学―最新の動向・治療動向―；鉄芽球性貧血　検査・診断・治療2017