HAYASHI TAKUMA 林琢磨

… Alternative Names

Hayashi Takuma 林琢磨

HAYASHI Takuma 林琢磨

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Researcher Number	60359726
Other IDs	https://orcid.org/0000-0002-7525-2048
External Links
Affiliation (Current)	2025: 独立行政法人国立病院機構(京都医療センター臨床研究センター), 展開医療研究部, 研究室長
Affiliation (based on the past Project Information) *help	2019 – 2024: 独立行政法人国立病院機構(京都医療センター臨床研究センター), 展開医療研究部, 研究室長 2016: 信州大学, 医学部, 特任教授 2014 – 2015: 信州大学, 学術研究院医学系, 准教授 2012 – 2013: 信州大学, 医学部, 准教授 2009 – 2011: Shinshu University, 医学系研究科, 准教授 2003 – 2004: 信州大学, 大学院・医学研究科, 助教授
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related / Pathological medical chemistry Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology
Keywords	Principal Investigator 子宮平滑筋肉腫 / LMP2 / RB / CDK4 / 子宮平滑筋腫 / MED12 / TP53 / ATRX / 子宮間葉性腫瘍 / 子宮筋腫 … More / immuno-proteasome / IDDM / IRF-1 / NOD / JAK1 / 子宮平滑筋種 / 子宮間葉系腫瘍 / 血行性転移 / リッキドバイオプシー / LMP2/b1i / cyclin E / 診断 / cyclin e / 標的因子 / バイオマーカー / INF-γ / 26Sプロテアソーム / 糖尿病 / 自己免疫疾患 / Immuno-proteasome / IFN-γ / 子宮肉腫 / CAVEOLIN1 / 血管新生 / 微小環境 / leiomyosarcome / angiogenesis / leiomyosarcoma / 老化 … More Except Principal Investigator リスク低減卵管卵巣摘出術 / 卵巣癌 / Cyclin E / CDK4 / TP53 / ATRX / 子宮平滑筋腫 / 子宮平滑筋肉腫 / 平滑筋幹細胞 / leimyosarcoma / main population / side population / Leiomyoma / Leiomyosarcoma / Main population / Side population / Cancer stem cell / side population(SP) / stem cells / non-SP / Side Population(SP) / leiomyosarcoma / leiomyoma / stem cell Less

Basic research for research and development of antitumor agents for intractable gynecologic tumors
- Principal Investigator
  
  小西郁生
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Department of Clinical Research, National Hospital Organization Kyoto Medical Center
卵巣がんの発生初期の免疫微小環境に着目した腹膜播種機構の解明と新規治療法の開発
- Principal Investigator
  
  安彦郁
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Department of Clinical Research, National Hospital Organization Kyoto Medical Center
Intractable disease: Construction of a foundation for research and development of new treatment methods for malignant uterine mesenchymal tumorsPrincipal Investigator
- Principal Investigator
  
  林琢磨
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Department of Clinical Research, National Hospital Organization Kyoto Medical Center
Development of preoperative diagnosis using liquid biopsy for uterine leiomyosarcomaPrincipal Investigator
- Principal Investigator
  
  Hayashi Takuma
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Department of Clinical Research, National Hospital Organization Kyoto Medical Center
婦人科悪性腫瘍に対する新規治療法の開発：子宮間葉系腫瘍の生物学的応答性の解析Principal Investigator
- Principal Investigator
  
  林琢磨
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Shinshu University
Molecular approach of characterize of uterine leiomyosarcoma:development of novel therapy against uterine mesenchymal tumoursPrincipal Investigator
- Principal Investigator
  
  HAYASHI Takuma
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Shinshu University
Comparative analysis of stem cells between normal and neoplastic myometric cells
- Principal Investigator
  
  SANO Kenji
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Shinshu University
For development of a new therapeutic approach : Examination of biological response of uterine leiomyosarcoma in microenvironmentsPrincipal Investigator
- Principal Investigator
  
  HAYASHI Takuma
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Shinshu University
Molecular approach on autoimmune disease, IDDM (insulin dependent diabetes mellitus) expression, involvement of defective LMP2 expressionPrincipal Investigator
- Principal Investigator
  
  HAYASHI Takuma
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Shinshu University Graduate School of Medicine

[Book] Highly conserved binding region of ACE2 as a receptor for SARS-CoV-2 between humans and mammals2023
- Author(s)
  Hayashi T, Abiko K, Mandai M, Yaegashi N, Konishi I
- Total Pages
  13
- Publisher
  Advanced Research in Biological Science: B P International eBook
- Data Source
  KAKENHI-PROJECT-19K09840
[Book] Prime Archives in Molecular Biology 2nd Edition2021
- Author(s)
  Tmura S. Hayashi T. Tokunaga H. Yaegashi N. Abiko K. Konishi I.
- Total Pages
  12
- Publisher
  Prime Archives in Molecular Biology
- Data Source
  KAKENHI-PROJECT-19K09840
[Book] 末病と抗老化2020
- Author(s)
  林琢磨*、市村友季、佐野健司、利根川進、八重樫伸生、小西郁生.
- Total Pages
  220
- Publisher
  (財)博慈会老人研究所
- Data Source
  KAKENHI-PROJECT-19K09840
[Book] Precision Medicine in Gynecology and Obstetrics2017
- Author(s)
  Hayashi T*, Sano K, Ichimura T, Kawano M, Kanai Y, Shiozawa T, Yaegashi N, Konishi, I.
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-15K10709
[Book] Current Research in Cancer2014
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Hiraoka N,Kasai M, Ichimura T, Nagase S, Ishiko O, Kanai Y, Yaegashi N, Aburatani H, Shiozawa T, Tonegawa S, Konishi I
- Total Pages
  24
- Publisher
  Research Media
- Data Source
  KAKENHI-PROJECT-24592510
[Journal Article] Molecular Histopathology for Establishing Diagnostic Method and Clinical Therapy for Ovarian Carcinoma2023
- Author(s)
  Hayashi T, Konishi I
- Journal Title
  
  J Clin Med Res
  
  Volume: 15(2) Issue: 2 Pages: 68-75
- DOI
  10.14740/jocmr4853
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09840, KAKENHI-PROJECT-23K08881, KAKENHI-PROJECT-23K27742
[Journal Article] Histopathological Findings of Ectopic Pregnancy in Contraceptive-Wearing Woman2023
- Author(s)
  Hayashi Takuma、Sano Kenji、Konishi Ikuo
- Journal Title
  
  Journal of Clinical Medicine Research
  
  Volume: 15 Issue: 7 Pages: 384-389
- DOI
  10.14740/jocmr4924
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K08881, KAKENHI-PROJECT-19K09840, KAKENHI-PROJECT-23K27742
[Journal Article] Characteristic of Endometrial Stromal Sarcoma by Algorithm of Potential Biomarkers for Uterine Mesenchymal Tumor2023
- Author(s)
  Hayashi Takuma、Sano Kenji、Yaegashi Nobuo、Abiko Kaoru、Konishi Ikuo
- Journal Title
  
  Current Issues in Molecular Biology
  
  Volume: 45 Issue: 8 Pages: 6190-6201
- DOI
  10.3390/cimb45080390
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16431, KAKENHI-PROJECT-19K09840
[Journal Article] Notes on the morphological features of cotyledonary dissecting leiomyoma, which is rare in clinical practice2023
- Author(s)
  Tamura S, Hayashi T, Yaegashi N, Abiko K, Konishi I.
- Journal Title
  
  Transl Cancer Res
  
  Volume: 12(3) Issue: 3 Pages: 452-455
- DOI
  10.21037/tcr-22-2605
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09840, KAKENHI-PROJECT-23K08881, KAKENHI-PROJECT-23K27742
[Journal Article] The Effect of mRNA-Based COVID-19 Vaccination on Anti-Programmed Cell Death Protein 1 Blockade for Nasopharyngeal Cancer May Differ From a Virus-Inactivated Vaccine2023
- Author(s)
  Hayashi Takuma、Konishi Ikuo
- Journal Title
  
  World Journal of Oncology
  
  Volume: 14 Issue: 4 Pages: 316-320
- DOI
  10.14740/wjon1620
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09840
[Journal Article] Familial Gastrointestinal Stromal Tumor Associated with Zebra-like Pigmentation2023
- Author(s)
  Hayashi Takuma Konishi Ikuo
- Journal Title
  
  Biomedicines
  
  Volume: 11 Issue: 6 Pages: 1590-1590
- DOI
  10.3390/biomedicines11061590
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K08881, KAKENHI-PROJECT-19K09840, KAKENHI-PROJECT-23K27742
[Journal Article] Importance of diagnostic methods for round ligament leiomyomas in clinical practice2023
- Author(s)
  Hayashi T, Yaegashi N, Tonegawa S, Konishi I
- Journal Title
  
  Quant Imaging Med Surg
  
  Volume: 13(3) Issue: 3 Pages: 2033-2037
- DOI
  10.21037/qims-22-1276
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09840, KAKENHI-PROJECT-23K08881, KAKENHI-PROJECT-23K27742
[Journal Article] Treatment With Antitumor Agents Recommended by Cancer Genome Panel for Uterine Leiomyosarcoma2023
- Author(s)
  Hayashi Takuma、Kishimoto Naoya、Abiko Kaoru、Konishi Ikuo
- Journal Title
  
  Journal of Clinical Medicine Research
  
  Volume: 15 Issue: 10-11 Pages: 461-468
- DOI
  10.14740/jocmr5052
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16431, KAKENHI-PROJECT-19K09840
[Journal Article] Characteristic of Concurrent Uterine Lipoleiomyoma and Hemangioma by Algorithm of Candidate Biomarkers for Uterine Mesenchymal Tumor2022
- Author(s)
  Nishikawa S, Hayashi T, Amano Y, Yaegashi N, Abiko K, Konishi I
- Journal Title
  
  Diagnostics (Basel)
  
  Volume: 12(10) Issue: 10 Pages: 2468-2468
- DOI
  10.3390/diagnostics12102468
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09840
[Journal Article] Pathological Evidence for Residual SARS-CoV-2 in the Micrometastatic Niche of a Patient with Ovarian Cancer2022
- Author(s)
  Hayashi T, Sano K, Yaegashi N, Konishi I
- Journal Title
  
  Curr Issues Mol Biol.
  
  Volume: 44(12) Issue: 12 Pages: 5879-5889
- DOI
  10.3390/cimb44120400
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09840
[Journal Article] Significant Decrease in Seasonal Influenza in the COVID-19 Era: Impact of Global Movement Restrictions?2021
- Author(s)
  Hayashi T, Konishi I.
- Journal Title
  
  J Clin Med Res.
  
  Volume: 13(3) Issue: 3 Pages: 191-194
- DOI
  10.14740/jocmr4450
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09840
[Journal Article] Oncological Properties of Intravenous Leiomyomatosis: Involvement of Mesenchymal Tumor Stem-Like Cells.2021
- Author(s)
  Tamura S, Hayashi T, Tokunaga H, Yaegashi N, Abiko K, Konishi I.
- Journal Title
  
  Curr Issues Mol Biol.
  
  Volume: 43(2) Issue: 2 Pages: 1188-1202
- DOI
  10.3390/cimb43020084
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09840
[Journal Article] Noneffect of SARS-CoV-2 spike glycoprotein Y217N mutation on affinity between the virus and ACE2.2021
- Author(s)
  Hayashi T, Konishi I.
- Journal Title
  
  J Biol Chem
  
  Volume: 296 Pages: 100725-100725
- DOI
  10.1016/j.jbc.2021.100725
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09840
[Journal Article] Development of Uterine Leiomyosarcoma During Follow-up After Caesarean Section in a Woman With Uterine Leiomyoma.2021
- Author(s)
  Watanabe K, Hayashi T, Katsumata M, Sano K, Abiko K, Konishi I.
- Journal Title
  
  Anticancer Res.
  
  Volume: 41(6) Issue: 6 Pages: 3001-3010
- DOI
  10.21873/anticanres.15082
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09840
[Journal Article] Potential Novel Ovarian Cancer Treatment Targeting Myeloid-Derived Suppressor Cells.2021
- Author(s)
  Abiko K, Hayashi T, Yamaguchi K, Mandai M, Konishi I.
- Journal Title
  
  Cancer Invest.
  
  Volume: 39(4) Pages: 310-314
- DOI
  10.1080/07357907.2020.1871487
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09840, KAKENHI-PROJECT-20K16431
[Journal Article] Initialization of epithelial cells by tumor cells in a metastatic microenvironment.2020
- Author(s)
  Hayashi T, Sano K, Aburatani H, Yaegashi N, Konishi I
- Journal Title
  
  Oncogene
  
  Volume: 39 Issue: 12 Pages: 2638-2640
- DOI
  10.1038/s41388-020-1171-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07013, KAKENHI-PROJECT-19K09840
[Journal Article] Characteristics of Leiomyosarcoma: Induction of Hematogenous Metastasis by Isolated Uterine Mesenchymal Tumor Stem-like Cells.2020
- Author(s)
  Hayashi T, Sano K, Ichimura T, Kanai Y, ZHARHARY D, Aburatani H, Yaegashi N, Konishi I.
- Journal Title
  
  Anticancer Research
  
  Volume: 40(3) Issue: 3 Pages: 1255-1265
- DOI
  10.21873/anticanres.14067
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09840, KAKENHI-PROJECT-18K07013
[Journal Article] Correlation of antitumor drug resistance with epigenetic regulation2020
- Author(s)
  Hayashi T, Konishi I
- Journal Title
  
  British Journal of Cancer
  
  Volume: 124(12) Issue: 4 Pages: 1-2
- DOI
  10.1038/s41416-020-01183-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09840
[Journal Article] Subspecies of SARS-CoV-2 from farmed minks might be a threat to humans2020
- Author(s)
  Hayashi T. Konishi I
- Journal Title
  
  Science
  
  Volume: 368(6496) Pages: 1-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09840
[Journal Article] Possibility of combination therapy with antitumor agents and agents for epigenetic changes in the treatment of glioblastoma2020
- Author(s)
  Hayashi T
- Journal Title
  
  JAMA Oncology
  
  Volume: 6(7) Pages: 1-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09840
[Journal Article] Profiling of Target Molecules for Immunotherapy in Mesenchymal Tumors.2019
- Author(s)
  Hayashi T, Ichimura T, Sano K, Tonegawa S, Kanai Y, Zharhary D, Aburatani H, Yaegashi N, Konishi I.
- Journal Title
  
  J Clin Med Res.
  
  Volume: 11(8) Issue: 8 Pages: 609-613
- DOI
  10.14740/jocmr3886
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09840, KAKENHI-PROJECT-18K07013
[Journal Article] Prospects and Problems of Cancer Genome Analysis for Establishing Cancer Precision Medicine.2019
- Author(s)
  Hayashi T, Konishi I.
- Journal Title
  
  Cancer Invest
  
  Volume: 37(9) Issue: 9 Pages: 427-431
- DOI
  10.1080/07357907.2019.1661428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09840
[Journal Article] Characterization of leiomyomatoid angiomatous neuroendocrine tumour (LANT)-like tumour in the myometrium with histopathological examination.2017
- Author(s)
  Hayashi T, Ichimura T, Kasai M, Sano K, Zharhary D, Shiozawa T, Yaegashi N, Konishi I.
- Journal Title
  
  Anticancer Research
  
  Volume: 39(10) Pages: 5127-5138
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10709
[Journal Article] Gene analysis of Interferon-g signal molecules in human uterine leiomyosarcoma.2016
- Author(s)
  Hayashi T, Kawano M, Ichimura T, Kasai M, Ida K, Ando H, Shiozawa T, Tonegawa S, Kanai Y, Aburatani H, Yaegashi N, Konishi I.
- Journal Title
  
  WULFENIA Journal
  
  Volume: 23(9) Pages: 1-18
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10709
[Journal Article] A Novel Diagnostic Biomarker, PSMB9/b1i, For Human Uterine Leiomyosarcoma.2016
- Author(s)
  Hayashi T, Kawano M, Ichimura T, Zharhary D, Kanai Y, Tonegawa S, Shiozawa T, Yaegashi N, Konishi I.
- Journal Title
  
  EC Gynaecology
  
  Volume: 01 Pages: 5-6
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10709
[Journal Article] Genomic Analysis of Sarcomagenesis2016
- Author(s)
  Hayashi T, Horiuchi A, Kanai Y, Yaegashi N, Shiozawa T, Tonegawa S, Konishi I.
- Journal Title
  
  Journal of Gynecology and Obstetrics Bulletin
  
  Volume: 1(1) Pages: 1-2
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10709
[Journal Article] Molecular Pathology and Novel Clinical Therapy for Uterine Leiomyosarcoma.2016
- Author(s)
  Hayashi T, Kawano M, Ichimura T, Ida K, Ando H, Zharhary D, Kanai Y, Aburatani H, Tonegawa S, Shiozawa T, Yaegashi N, Konishi I.
- Journal Title
  
  Anticancer Research
  
  Volume: 38 Pages: 4997-5007
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10709
[Journal Article] Mouse models of sarcoma for understanding of the tumourigenesis2015
- Author(s)
  Hayashi T
- Journal Title
  
  PARIPEX-Indian Journal of Research
  
  Volume: 4(4) Pages: 4-5
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592510
[Journal Article] Uterine Leiomyosarcoma Tumorigenesis in Lmp2-deficient Mice: Involvement of Impaired Anti-oncogenic Factor IRF12015
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Yaegashi N, Konishi I
- Journal Title
  
  Anticancer Research
  
  Volume: 35(9) Pages: 4665-4679
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10709
[Journal Article] Detection of somatic mutations in Interferon-γ signal molecules in human uterine leiomyosarcoma.2015
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Hiraoka N, Ichimura T, Ishiko O, Kanai Y, Yaegashi N, Aburatani H, Konishi I.
- Journal Title
  
  Int’l J of Biological and Pharmaceutical Research
  
  Volume: 6 Pages: 1-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659776
[Journal Article] Differential expressions of CAVEOLIN 1 in human uterine mesenchymal tumors and normal myometrium2015
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Hiraoka N, Ichimura T, Ishiko O, Kanai Y, Yaegashi N, Shiozawa T, Tonegawa S, Aburatani H, Konishi I
- Journal Title
  
  Jokull Journal
  
  Volume: 65(7) Pages: 1-15
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10709
[Journal Article] Somatic mutations in Interferon-ｇ; signal molecules in human uterine leiomyosarcoma2015
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Hiraoka N, Ichimura T, Ishiko O, Kanai Y, Yaegashi N, Aburatani H, Konishi I
- Journal Title
  
  International Journal of Medical Science And Clinical Inventions
  
  Volume: 2(4) Pages: 846-850
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592510
[Journal Article] Expression of CAVEOLIN 1 in uterine mesenchymal tumors: no relationship between malignancy and CAVEOLIN 1 expression2015
- Author(s)
  Hayashi T, Ichimura T, Yaegashi N, Shiozawa T, Konishi I
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 15 Issue: 4 Pages: 1-12
- DOI
  10.1016/j.bbrc.2015.06.046
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10709, KAKENHI-PROJECT-26670721
[Journal Article] Molecular approach of tumorigenesis of human uterine leiomyosarcoma: Structure modeling of JAK1 molecule with somatic mutation2015
- Author(s)
  Hayashi T, Horiuchi A. Sano K. Ichimura T. Hiraoka N. Sudo T. Nishimura R. Ishiko O. Kanai Y. Yaegashi N. Aburatani H. Shiozawa T. Tonegawa S. Konishi.I
- Journal Title
  
  Jokull Journal
  
  Volume: 65(3) Pages: 1-21
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592510
[Journal Article] The identification of somatic mutations in Interferon-γ signaling molecules in human uterine leiomyosarcoma.2014
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Hiraoka N, Ichimura T, Ishiko O, Kanai Y, Yaegashi N, Shiozawa T, Aburatani H, Ikuo Konishi I.
- Journal Title
  
  Jokull Journal
  
  Volume: 64 Pages: 1-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659776
[Journal Article] Identification of novel biomarker for human uterine leiomyosarcoma2014
- Author(s)
  Hayashi T, Horiuchi A, Aburatani H, Ishiko O, Yaegashi N, Kanai Y, Zharhary D, Tonegawa S, Konishi I
- Journal Title
  
  J Hematology and Oncology
  
  Volume: 1 Pages: 1-6
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592510
[Journal Article] Molecular approach of leiomyosarcoma: critical founction of LMP2 in our understanding of the pathobiology.2014
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Hiraoka N,Kasai M, Ichimura T, Nagase S, Ishiko O, Kanai Y, Yaegashi N, Aburatani H, Shiozawa T, Tonegawa S, Konishi I.
- Journal Title
  
  Current Research in Cancer
  
  Volume: 5 Pages: 10-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659776
[Journal Article] LMP2/β1i as a potential biomarker of human uterine mesenchymal tumors when combined with the candidate molecules, cyclin E and calponin h1.2014
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Gal Gur G, Aburatani H, Ishiko O, Yaegashi N, Kanai Y, Zharhary D, Tonegawa S, Konishi I.
- Journal Title
  
  J Mol Pathophysiol
  
  Volume: 3 Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659776
[Journal Article] A diagnostic biomarker: differential expression of LMP2/β1i in human uterine neoplasms.2014
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Hiraoka N, Ichimura T, Ishiko O, Kanai Y, Yaegashi N, Shiozawa T, Aburatani H, Tonegawa S, and Konishi I.
- Journal Title
  
  Journal of Clinical & Experimental Oncology
  
  Volume: 3 Issue: 03 Pages: 1-3
- DOI
  10.4172/2324-9110.1000128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659776
[Journal Article] Preoperative Diagnosis of Usual Leiomyoma, Atypical Leiomyoma, and Leiomyosarcoma2014
- Author(s)
  Matsuda M, Ichimura T, Kasai M, Murakami M, Kawamura N, Hayashi T, and Sumi T
- Journal Title
  
  Sarcoma
  
  Volume: 2014 Pages: 34-38
- DOI
  10.1155/2014/498682
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592510
[Journal Article] The detection of somatic mutations in Interferon-γ signal molecules in human uterine leiomyosarcoma.2014
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Hiraoka N, Ichimura T, Ishiko O, Kanai Y, Yaegashi N, Aburatani H, Konishi I.
- Journal Title
  
  Sarcoma Research - International
  
  Volume: 1 Pages: 1-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659776
[Journal Article] Potential biomarker for human uterine leiomyosarcoma2014
- Author(s)
  Hayashi T, Horiuchi A, Aburatani H, Ishiko O, Yaegashi N, Kanai Y, Zharhary D, Shiozawa T, Tonegawa S, Konishi I
- Journal Title
  
  Journal of Clinical Medicine Research
  
  Volume: 6 Pages: 392-394
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592510
[Journal Article] Potential diagnostic biomarkers: LMP2/ｂ1i and Cyclin B1 differential expression in human uterine mesenchymal tumors2014
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Hiraoka N, Ichimura T, Sudo T, Ishiko O, Yaegashi N, Aburatani H, Konishi I
- Journal Title
  
  TUMORI
  
  Volume: 100 Pages: 509-516
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592510
[Journal Article] Potential diagnostic biomarkers: LMP2/β1i and Cyclin B1 differential expression in human uterine mesenchymal tumors.2014
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Hiraoka N, Ichimura T, Sudo T, Ishiko O, Yaegashi N, Aburatani H, Konishi I.
- Journal Title
  
  TUMORI
  
  Volume: 100 Pages: 509-516
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659776
[Journal Article] The identification of somatic mutations in Interferon-ｇ; signaling molecules in human uterine leiomyosarcoma2014
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Hiraoka N, Ichimura T, Ishiko O, Kanai Y, Yaegashi N, Shiozawa T, Aburatani H, Ikuo Konishi I
- Journal Title
  
  Jokull Journal
  
  Volume: 64 Pages: 1-20
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592510
[Journal Article] A novel diagnostic marker: Proteasome LMP2/b1i-differential expression in human uterus mesenchymal tumors.2013
- Author(s)
  Hayashi T, Horiuchi. A, Yaegashi. N, Shiozawa.T, Tonegawa.S, Konishi I
- Journal Title
  
  Cancer Research Journal
  
  Volume: 1(1) Issue: 1 Pages: 1-6
- DOI
  10.11648/j.crj.20130101.11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592510
[Journal Article] Association of proteasome subunit LMP2/β1i with the development of human uterine mesenchymal tumors.2013
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Hiraoka N, Ichimura T, Ishiko O, Kanai Y, Yaegashi N, Aburatani H, Shiozawa T, Tonegawa S, Konishi I.
- Journal Title
  
  Current Res. Cancer.
  
  Volume: 2 Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659776
[Journal Article] Proteasome Subunit LMP2/ b1i As a Biomarker for Human Uterine Mesenchymal Tumors.2013
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Gur G, Aburatani H, Ishiko O, Yaegashi N, Shiozawa T, Kanai Y, Zharhary D, Tonegawa S, Konishi I
- Journal Title
  
  J Oncobiomarkers
  
  Volume: 1(2) Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592510
[Journal Article] Tumor escape of uterine leiomyosarcoma from immune surveillance in the female genital system.2013
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Hiraoka N, Ichimura T, Ishiko O, Kanai Y, Yaegashi N, Aburatani H, Shiozawa T, Tonegawa S, Konishi I.
- Journal Title
  
  Current Res. Immunol.
  
  Volume: 7 Pages: 13-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659776
[Journal Article] 子宮平滑筋肉腫の新規診断法：LMP2とCalponin h1のバイオマーカーとしての信頼性2013
- Author(s)
  林琢磨, 堀内晶子, 利根川進, 小西郁生
- Journal Title
  
  末病と抗老化
  
  Volume: 22 Pages: 50-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592510
[Journal Article] Differential expression of LMP2/β1i: as a potential biomarkeral of human uterine mesenchymal tumors.2013
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Gur G, Aburatani H, Ishiko O, Yaegashi N, Kanai Y, Zharhary D, Tonegawa S, Konishi I.
- Journal Title
  
  J Interdisciplinary Histopathology
  
  Volume: 1 Issue: 3 Pages: 153-159
- DOI
  10.5455/jihp.20130210114005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659776, KAKENHI-PROJECT-24592510
[Journal Article] The proteasome subunit LMP2/β1i in the female genital system.2013
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Gur G, Aburatani H, Ichimura T, Yaegashi N, Kanai Y, Zharhary D, Tonegawa S, Konishi I.
- Journal Title
  
  Journal Gynecology Obstetrics
  
  Volume: 1 Issue: 1 Pages: 1-6
- DOI
  10.11648/j.jgo.20130101.11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659776, KAKENHI-PROJECT-24592510
[Journal Article] Proteasome Subunit LMP2/ β1i As a Biomarker for Human Uterine Mesenchymal Tumors.2013
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Gur G, Aburatani H, Ishiko O, Yaegashi N, Shiozawa T, Kanai Y, Zharhary D, Tonegawa S, Konishi I.
- Journal Title
  
  J Oncobiomarkers
  
  Volume: 1 Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659776
[Journal Article] Involvement of pelvic inflammation-related mismatch repair abnormalities and microsatellite instability in the malignant transformation of ovarian endometriosis.2012
- Author(s)
  Fuseya C, Horiuchi A, Hayashi A, Suzuki A, Miyamoto T, Hayashi T, Shiozawa T.
- Journal Title
  
  Hum Pathol.
  
  Volume: 43 Issue: 11 Pages: 1964-72
- DOI
  10.1016/j.humpath.2012.02.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390310, KAKENHI-PROJECT-22591850, KAKENHI-PROJECT-23592442, KAKENHI-PROJECT-24592510
[Journal Article] A potential diagnostic biomarker: Proteasome subunit LMP2/b1i-differential expression in human uterus neoplasm.2012
- Author(s)
  Hayashi T, Horiuchi A, Aburatani H, Ishiko O, Yaegashi N, Tonegawa S, Konishi I
- Journal Title
  
  Diagnostic and Therapeutic Study
  
  Volume: 1 Pages: 45-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592510
[Journal Article] Proteasome LMP2/b1i-differential expression in human uterine mesenchymal tumor.2012
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Gur G, Aburatani H, Ishiko O, Yaegashi N, Shiozawa T, Kanai Y, Zharhary D, Tonegawa S, Konishi I.
- Journal Title
  
  Current Res. Cancer
  
  Volume: 1 Pages: 17-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592510
[Journal Article] Tumor immunoediting: T cell-mediated immune surveillance to uterine leiomyosarcoma.2012
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Hiraoka N, Kasai M, Ichimura T, Nagase S, Ishiko O, Kanai Y, Yaegashi N, Aburatani H, Shiozawa T, Tonegawa S, Konishi I.
- Journal Title
  
  Current Res. Immunol
  
  Volume: 1 Pages: 9-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592510
[Journal Article] Potential role of LMP2 as an anti-oncogenic factor in human uterine leiomyosarcoma: morphological significance of calponin h12012
- Author(s)
  Hayashi T,Horiuchi A,Sano K,Hiraoka N,Kasai M,Ichimura T,Sudo T,Nishimura R,Ishiko O,Shiozawa T,Kanai Y,Yaegashi N,Aburatani H,Konishi I.
- Journal Title
  
  FEBS Lett
  
  Volume: 586 Issue: 13 Pages: 1824-31
- DOI
  10.1016/j.febslet.2012.05.029
- NAID
  120007110569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591850, KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-23592449, KAKENHI-PROJECT-23659776, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-24592510
[Journal Article] Biological Significance of the Proteasome Subunit LMP2/β1i as a Tumor Suppresso in Human Uterine Leiomyosarcoma.2012
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Gur G, Aburatani H, Ishiko O, Yaegashi N, Shiozawa T, Kanai Y, Zharhary D, Tonegawa S, Konishi I.
- Journal Title
  
  J Cancer Res. Updates
  
  Volume: 1 Issue: 2 Pages: 181-188
- DOI
  10.6000/1929-2279.2012.01.02.4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659776, KAKENHI-PROJECT-24592510
[Journal Article] Tumor Immuno editing from T cell-Mediated Immune Surveillance to Tumor-Escape of Uterine Laiomyosarcoma2012
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Hiraoka N, Ichimura T, Ishiko O, Kanai Y, Yaegashi N, Aburatani H, Shiozawa T, Tonegawa S, Konishi I
- Journal Title
  
  J Vaccines Vacci
  
  Volume: 1 Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592510
[Journal Article] Hypoxia up regulates ovarian cancer invasiveness via the binding of HIF-1αto a hypoxia-induced, methylation-free hypoxia response element of S100A4 gene2012
- Author(s)
  Horiuchi A, Hayashi T, Kikuchi N, Hayashi A, Fuseya C, Shiozawa T, Konishi I.
- Journal Title
  
  Int J Cancer
  
  Volume: 27 Issue: 8 Pages: 755-67
- DOI
  10.1002/ijc.27448
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390452, KAKENHI-PROJECT-22591850, KAKENHI-PROJECT-22791524, KAKENHI-PROJECT-24592510
[Journal Article] Tumor Immunoediting from T cell-Mediated Immune Surveillance to Tumor-Escape of Uterine Laiomyosarcoma2012
- Author(s)
  Hayashi T, Horiuchi A, Sano K, HiraokaN, Ichimura T, Ishiko O, Kanai Y, Yaegashi N, Aburatani H, Shiozawa T, Tonegawa S, Konishi I
- Journal Title
  
  J Vaccines Vacci
  
  Volume: S1 Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592126
[Journal Article] A POTENTIAL DIAGNOSTIC BIOMARKER FOR HUMAN UTERINE MESENCHYMAL TUMOR: PROTEASOME LMP2/b 1i SUBUNIT-DIFFERENTIAL EXPRESSION2012
- Author(s)
  Hayashi T, Horiuchi A, Gur G, Aburatani H, Ishiko O, Yaegashi N, Shiozawa T, Zharhary D, Tonegawa S, Konishi I
- Journal Title
  
  Advance Laboratory Medicine International
  
  Volume: 2 Pages: 78-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592510
[Journal Article] Hypoxia upregulates ovarian cancer invasiveness via the binding of HIF-1a to a hypoxia-induced, methylation free hypoxia response element(HRE) of S100A4 gene2011
- Author(s)
  Horiuchi A, Hayashi T, Kikuchi N, Hayashi A, Fuseya C, Shiozawa T andKonishi I
- Journal Title
  
  Intl. J. Cancer
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592126
[Journal Article] Molecular approach on uterine leiomyosarcoma : LMP2-deficient mice as an animal model of spontaneous uterine leiomyosarcoma2011
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Hiraoka N, Kanai Y, Shizawa T, Tonegawa S, Konishi I
- Journal Title
  
  Sarcoma
  
  Volume: 1 Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592126
[Journal Article] Potential role of LMP2 as tumor-suppressor defines new targets for uterine leiomyosarcoma therapy2011
- Author(s)
  Hayashi, T, A.Horiuchi, K.Sano, N.Hiraoka, M.Kasai, T.Ichimura, T.Sudo, Y.Tagawa, R.Nishimura, Ol Ishiko, Y.Kanai, N.Yaegashi, H.Aburatani, T.Shiozawa, I.Konishi
- Journal Title
  
  Sci Rep
  
  Volume: 1 Issue: 1 Pages: 180-180
- DOI
  10.1038/srep00180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300178, KAKENHI-PROJECT-21390452, KAKENHI-PROJECT-21592126, KAKENHI-PROJECT-22591850, KAKENHI-PROJECT-23659776
[Journal Article] Involvement of proteasome ss1i subunit, LMP2, on development of uterin leiomyosarcma2011
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Hiraoka N, Kasai M, Ichimura T, Nagase S, Ishiko O, Kanai Y, Yaegashi N, Aburatani H, Shiozawa T, Tonegawa S, Konishi I
- Journal Title
  
  North Ame J Med Sci
  
  Volume: 3 Pages: 394-399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592126
[Journal Article] Potential role of LMP2 astumor-suppressor defines new targets for uterine leiomyosarcoma therapy2011
- Author(s)
  Hayashi T, Horiuchi A, Sano K, HiraokaN, Kanai Y, Aburatani H, Shizawa T, andKonishi I
- Journal Title
  
  Scientific Reports
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592126
[Journal Article] Molecular Approach to Uterine Leiomyosarcoma : LMP2-Deficient Mice as an Animal Model of Spontaneous Uterine Leiomyosarcoma2011
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Hiraoka N, Kanai Y, Shiozawa T, Tonegawa S, Konishi I.
- Journal Title
  
  Sarcoma
  
  Volume: 2011 Pages: 476498-476498
- DOI
  10.1155/2011/476498
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390452, KAKENHI-PROJECT-22591850, KAKENHI-PROJECT-23659776
[Journal Article] Involvement of LMP2, IFN-γ-inducible factor, on development of uterine leiomyosarcma2011
- Author(s)
  Hayashi T, Horiuchi A, Sano K, HiraokaN, Kasai M, Ichimura T, Nagase S, IshikoO, Kanai Y, Yaegashi N, Aburatani H, Shiozawa T, Tonegawa S, Konishi I
- Journal Title
  
  Current Res. Immunol
  
  Volume: 5 Pages: 51-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592126
[Journal Article] Involvement of proteasomeβ1i subunit, LMP2, on development of uterin leiomyosarcma2011
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Hiraoka N, Kasai M, Ichimura T, Nagase S, Ishiko O, Shiozawa T, Kanai Y, Yaegashi N, Aburatani H, Tonegawa S, Konishi I.
- Journal Title
  
  N Am J Med Sci
  
  Volume: 3(9) Pages: 394-9
- DOI
  10.4297/najms.2011.3394
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390452, KAKENHI-PROJECT-23659776
[Journal Article] Tumor immunoediting ; from immunosurveillance to tumor-escape on uterine leiomyosarcma2011
- Author(s)
  Hayashi T, Horiuchi A, Sano K, HiraokaN, Kasai M, Ichimura T, Nagase S, IshikoO, Kanai Y, Yaegashi N, Aburatani H, Shiozawa T, Tonegawa S, Konishi I
- Journal Title
  
  Current Res. Cancer
  
  Volume: 4 Pages: 36-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592126
[Journal Article] Involvement of proteasomeβ1i subunit, LMP2, on development of uterine leiomyosarcma2011
- Author(s)
  Hayashi T, Horiuchi A, Sano K, HiraokaN, Kasai M, Ichimura T, Nagase S, IshikoO, Kanai Y, Yaegashi N, Aburatani H, Shiozawa T, Tonegawa S, Konishi I
- Journal Title
  
  North Ame J Med Sci
  
  Volume: 3 Pages: 394-399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592126
[Journal Article] Molecular approach on uterine leiomyosarcoma : LMP2-deficient mice as an animal model of spontaneous uterine leiomyosarcoma2011
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Hiraoka N, Kanai Y, Shizawa T, Tonegawa S and Konishi I
- Journal Title
  
  Sarcoma
  
  Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592126
[Journal Article] Mice-lacking LMP2, proteasome subunit, as an animal model of spontaneous uterine leiomyosarcoma2010
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Hiraoka N, Kanai Y, Shiozawa T, Tonegawa S and Konishi I
- Journal Title
  
  Protein and Cell
  
  Volume: 1 Pages: 711-717
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592126
[Journal Article] Type-specific roles of histone deacetylase(HDAC)overexpression in ovarian carcinoma : HDACl enhances cell proliferation and HDAC3 stimulates cell migration with down-regulation of E-cadherin.2010
- Author(s)
  Akiko Hayashi
- Journal Title
  
  International J. Cancer 126
  
  Pages: 1-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592126
[Journal Article] Mice-lacking LMP2, IFN-γ-inducible factor, as an Animal Model of Spontaneous Uterine Leiomyosarcoma2010
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Hiraoka N, Kanai Y, Aburatani H, Shiozawa T, Tonegawa S and Konishi I
- Journal Title
  
  Current Res. Immunol
  
  Volume: 4 Pages: 1-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592126
[Journal Article] Mice-lacking LMP2, IFN-γ-inducible factor, as an Animal Model of Spontaneous Uterine Leiomyosarcoma2010
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Hiraoka N, Kanai Y, Aburatani H, Shiozawa T, Tonegawa S, Konishi I
- Journal Title
  
  Curren t Res.Immunol
  
  Volume: 4 Pages: 1-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592126
[Journal Article] Molecular approach on uterine leiomyosarcoma : LMP2-deficient mice as an animal model of spontaneous uterine leiomyosarcoma2010
- Author(s)
  Hayashi T, Horiuchi A, Sano K, HiraokaN, Kanai Y, Shiozawa T, Tonegawa S andKonishi I
- Journal Title
  
  The Molecular Basis of Sarcoma
  
  Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592126
[Journal Article] Tumor immunoediting : from immunosurveillance to tumor escape-incase of uterine leiomyosarcoma-.2009
- Author(s)
  Takuma Hayashi
- Journal Title
  
  Current Research Immunology 1
  
  Pages: 33-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592126
[Journal Article] Priorityの重要性:ヒト子宮平滑筋肉腫のバイオマーカーの発見と新規診断法の確立2009
- Author(s)
  林琢磨
- Journal Title
  
  癌と人 36
  
  Pages: 57-58
- NAID
  120005223284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592126
[Journal Article] Fuzeon, First of the so-called "fusion inhibitor" drug in new class of AIDS treatments and its warning2005
- Author(s)
  Hayashi T.
- Journal Title
  
  J.J.Clinical Med. 63
  
  Pages: 173-182
- Data Source
  KAKENHI-PROJECT-15590269
[Journal Article] Fuzeon, First of the so-called "fusion inhibitor" drug in new class of AIDS treatments and its warnings2005
- Author(s)
  Hayashi T.
- Journal Title
  
  J.J.Clinical Med. 63
  
  Pages: 173-182
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590269
[Journal Article] 形態形成におけるアポトーシスの役割2003
- Author(s)
  林琢磨
- Journal Title
  
  実験医学 21
  
  Pages: 2585-2585
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590269
[Journal Article] First of the so-called "fusion inhibitor" drug in new class of AIDS treatments and its warnings.2003
- Author(s)
  Hayashi T, Fuzeon
- Journal Title
  
  J.J.Clinical Med. 63
  
  Pages: 173-182
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590269
[Journal Article] Central role of defective apoptosis in autoimmunity.2003
- Author(s)
  Kuhtreiber WM, Hayashi T, et al.
- Journal Title
  
  J.Mol.Endocrinol. 31
  
  Pages: 373-399
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590269
[Journal Article] Efective function of programmed cell death on developmental stage.2003
- Author(s)
  Hayashi T.
- Journal Title
  
  Experimental Medicine. 21
  
  Pages: 2585-2585
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590269
[Journal Article] Molecular approach on uterus tumorgenesis, involvement of defective proteasome activation.2003
- Author(s)
  Hayashi T.
- Journal Title
  
  Experimental Medicine. 21
  
  Pages: 952-956
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590269
[Journal Article] 子宮肉腫の発症機構:26Sプロテアソームの不活性化の発癌関与2003
- Author(s)
  林琢磨
- Journal Title
  
  実験医学 21
  
  Pages: 952-956
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590269
[Journal Article] Role of defective apoptosis in type 1 diabetes and other autoimmune diseases.2003
- Author(s)
  Hayashi T, Faustman DL.
- Journal Title
  
  Recent Prog Horm Res. 58
  
  Pages: 131-153
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590269
[Patent] 子宮間葉性腫瘍に対する予後予測法の開発2023
- Inventor(s)
  林琢磨、天野泰彰、安彦郁、小西郁生
- Industrial Property Rights Holder
  国立病院機構本部
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-015220
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-23K27742
[Patent] 子宮間葉性腫瘍に対する予後予測法の開発2023
- Inventor(s)
  林琢磨、佐野健司、天野泰彰、安彦郁、小西郁生
- Industrial Property Rights Holder
  国立病院機構本部
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-015220
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-23K08881
[Patent] 子宮間葉性腫瘍に対する予後予測法の開発2023
- Inventor(s)
  林琢磨、天野泰彰、安彦郁、小西郁生
- Industrial Property Rights Holder
  国立病院機構本部
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-015220
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-19K09840
[Patent] Detection of uterine leiomyosarcoma using LMP22008
- Inventor(s)
  林琢磨、堀内晶子、小林幸弘、佐野健司、小西郁生
- Industrial Property Rights Holder
  国立大学法人,信州大学
- Filing Date
  2008-05-30
- Acquisition Date
  2012-03-02
- Overseas
- Data Source
  KAKENHI-PROJECT-21592126
[Patent] LMP2 for use as a marker in detecting uterine leiomyosarcoma2008
- Inventor(s)
  林琢磨、堀内晶子、小林幸弘、佐野健司、小西郁生
- Industrial Property Rights Holder
  国立大学法人,信州大学
- Filing Date
  2008-06-24
- Acquisition Date
  2011-08-24
- Overseas
- Data Source
  KAKENHI-PROJECT-21592126
[Patent] ヒト子宮平滑筋肉腫の新規鑑別マーカー:イムノプロテアソームLMP22005
- Inventor(s)
  林琢磨
- Industrial Property Rights Holder
  国立大学法人,信州大学
- Filing Date
  2005-11-30
- Overseas
- Data Source
  KAKENHI-PROJECT-21592126
[Patent] ヒト子宮平滑筋肉腫の新規鑑別マーカー:イムノプロテアソームLMP22005
- Inventor(s)
  林琢磨、小林幸弘、佐野健司、堀内晶子、小西郁生
- Industrial Property Rights Holder
  国立大学法人信州大学
- Filing Date
  2005-11-30
- Data Source
  KAKENHI-PROJECT-21592126
[Patent] LMP2を用いた子宮平滑筋肉腫の検出2005
- Inventor(s)
  林琢磨、堀内晶子、小林幸弘、佐野健司、小西郁生
- Industrial Property Rights Holder
  国立大学法人,信州大学
- Industrial Property Number
  2007-548042
- Filing Date
  2005-11-30
- Acquisition Date
  2012-04-03
- Data Source
  KAKENHI-PROJECT-21592126
[Patent] ヒト子宮平滑筋肉腫の新規鑑別マーカー:イムノプロテアソームLMP22005
- Inventor(s)
  林琢磨、小林幸弘、佐野健司、堀内晶子、小西郁生
- Industrial Property Rights Holder
  国立大学法人信州大学
- Filing Date
  2005-11-30
- Acquisition Date
  2011-08-24
- Overseas
- Data Source
  KAKENHI-PROJECT-21592126
[Patent] ヒト子宮平滑筋肉腫の新規鑑別マーカー:イムノプロテアソームLMP22005
- Inventor(s)
  林琢磨、小林幸弘、佐野健司、堀内晶子、小西郁生
- Industrial Property Rights Holder
  国立大学法人信州大学
- Filing Date
  2005-11-30
- Overseas
- Data Source
  KAKENHI-PROJECT-21592126
[Presentation] Results of clinical research (PRUM-IBIO study): establishment of prognostic biomarkers for uterine mesenchymal tumors2023
- Author(s)
  Hayashi T, Sano K, Abiko K, Naegashi N, Konishi I
- Organizer
  Intel. Gynecol. Cancer Soci. IGCS 2023
- Invited
- Data Source
  KAKENHI-PROJECT-23K08881
[Presentation] 妊婦検診で確認された子宮間葉性腫瘍の腫瘍学的特徴の解析 PRUM-iBio study22023
- Author(s)
  林琢磨、佐野健司、市村友季、天野泰彰、徳永英樹、安彦郁、利根川進、万代昌紀、八重樫伸生、小西郁生
- Organizer
  2023日本婦人科腫瘍学会
- Data Source
  KAKENHI-PROJECT-23K08881
[Presentation] Examination of the affinity of anti-SARS-CoV-2 IgA, which is mucosal immunity, for SARS-CoV-2 BA.4 variant and BA.5 variant2023
- Author(s)
  Hayashi T, Konishi I
- Organizer
  2023 ASBMB Meetings. USA
- Data Source
  KAKENHI-PROJECT-23K27742
[Presentation] Examination of the affinity of anti-SARS-CoV-2 IgA, which is mucosal immunity, for SARS-CoV-2 BA.4 variant and BA.5 variant.2023
- Author(s)
  Hayashi T
- Organizer
  2023 ASBMB Meetings.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09840
[Presentation] Usefulness of cancer genome medicine using cancer gene panel for advanced uterine leiomyosarcoma2023
- Author(s)
  Hayashi T, Abiko K, Kishimoto K, Konishi I
- Organizer
  The 2nd JCA-AACR Precision Cancer Medicine International Conference. Kyoto. Japan. June 28-30, 2023.
- Data Source
  KAKENHI-PROJECT-23K08881
[Presentation] 妊婦検診で確認された子宮間葉性腫瘍の腫瘍学的特徴の解析 PRUM-iBio study2.2023
- Author(s)
  林琢磨、佐野健司、市村友季、天野泰彰、徳永英樹、安彦郁、利根川進、万代昌紀、八重樫伸生、小西郁生
- Organizer
  日本婦人科腫瘍学会Matsue, Shimane, Japan
- Data Source
  KAKENHI-PROJECT-19K09840
[Presentation] 進行子宮平滑筋肉腫に対するがん遺伝子パネルを用いたがんゲノム医療の有用性2023
- Author(s)
  Hayashi T, Konishi I
- Organizer
  第9回日本産科婦人科遺伝診療学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K09840
[Presentation] 進行子宮平滑筋肉腫に対するがん遺伝子パネルを用いたがんゲノム医療の有用性2023
- Author(s)
  Hayashi T, Konishi I.
- Organizer
  第9回日本産科婦人科遺伝診療学会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-23K08881
[Presentation] 進行子宮平滑筋肉腫に対するがん遺伝子パネルを用いたがんゲノム医療の有用性2023
- Author(s)
  Hayashi T, Konishi I.
- Organizer
  第9回日本産科婦人科遺伝診療学会学術講演会
- Data Source
  KAKENHI-PROJECT-23K27742
[Presentation] Usefulness of cancer genome medicine using cancer gene panel for advanced uterine leiomyosarcoma.2023
- Author(s)
  Hayashi T, Abiko K, Kishimoto K, Konishi I
- Organizer
  The 2nd JCA-AACR Precision Cancer Medicine International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09840
[Presentation] Examination of the affinity of anti-SARS-CoV-2 IgA, which is mucosal immunity, for SARS-CoV-2 BA.4 variant and BA.5 variant2023
- Author(s)
  Takuma Hayashi
- Organizer
  2023 ASBMB Meetings.
- Data Source
  KAKENHI-PROJECT-23K08881
[Presentation] Results of clinical research (PRUM-IBIO study): establishment of prognostic biomarkers for uterine mesenchymal tumors2023
- Author(s)
  Hayashi T, Sano K, Abiko K, Naegashi N, Konishi I
- Organizer
  Intel. Gynecol. Cancer Soci. IGCS 2023.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09840
[Presentation] Results of clinical research (PRUM-IBIO study): establishment of prognostic biomarkers for uterine mesenchymal tumors2023
- Author(s)
  Hayashi T, Sano K, Abiko K, Naegashi N, Konishi I.
- Organizer
  Intel. Gynecol. Cancer Soci. IGCS 2023.
- Data Source
  KAKENHI-PROJECT-23K27742
[Presentation] 妊婦検診で確認された子宮間葉性腫瘍の腫瘍学的特徴の解析 PRUM-iBio study2.2023
- Author(s)
  林琢磨、佐野健司、市村友季、天野泰彰、徳永英樹、安彦郁、利根川進、万代昌紀、八重樫伸生、小西郁生
- Organizer
  日本婦人科腫瘍学会2023
- Invited
- Data Source
  KAKENHI-PROJECT-23K27742
[Presentation] Usefulness of cancer genome medicine using cancer gene panel for advanced uterine leiomyosarcoma2023
- Author(s)
  Hayashi T, Abiko K, Kishimoto K, Konishi I.
- Organizer
  The 2nd JCA-AACR Precision Cancer Medicine International Conference. Kyoto. Japan
- Data Source
  KAKENHI-PROJECT-23K27742
[Presentation] Molecular Pathological analysis of uterine rhabdomyosarcoma and mesenchymal tumors.2022
- Author(s)
  Tamura S. Hayashi T. Ichimura T. Yaegashi N. Abiko K. Konishi I.
- Organizer
  3rd International E-conference Conference on Cancer Science and Therapy
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09840
[Presentation] 子宮間葉性腫瘍の血行性転移に関する腫瘍バイオマーカーの解析：PRUM iBio study2022
- Author(s)
  林琢磨、八重樫伸生、小西郁生
- Organizer
  第64回日本婦人科腫瘍学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K09840
[Presentation] Oncological features of intravenous leiomyomatosis: involvement of mesenchymal tumor stem-like cells2022
- Author(s)
  Tamura S. Hayashi T. Tokunaga H. Yaegashi N. Abiko K. Konishi I
- Organizer
  7th World Congress on CANCER RESEARCH AND THERAPY" (WCCRT-2022)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09840
[Presentation] Correlation of anti-tumour drug resistance with epigenetic regulation.2022
- Author(s)
  Hayashi T, Sano K, Yaegashi N, Konishi I.
- Organizer
  19th Annual Congress of IDDST.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09840
[Presentation] Molecular approach of uterine mesenchymal tumor for development of therapy.2022
- Author(s)
  Takuma Hayashi, Kenji Sano, Susumu Tonegawa, Nobuo Yaegashi, Ikuo Konishi.
- Organizer
  WCC-2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09840
[Presentation] Molecular Pathology of uterine mesenchymal tumors for development of diagnosis and clinical therapy.2021
- Author(s)
  Hayashi T. Ichimura T. Mandai M. Tonegawa S. Yaegasgi N. Konishi I.
- Organizer
  Biotechnology and Genetics World Forum to be held during November 04-06, 2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09840
[Presentation] Molecular Pathology of uterine mesenchymal tumors.2021
- Author(s)
  Hayashi T. Ichimura T. Mandai M. Tonegawa S. Yaegasgi N. Konishi I.
- Organizer
  Int'l Conference on Stem Cell Research and Therapy (SCRT 2021)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09840
[Presentation] Molecular Pathology of uterine mesenchymal tumors for development of diagnosis and clinical therapy.2021
- Author(s)
  Hayashi T. Ichimura T. Mandai M. Tonegawa S. Yaegasgi N. Konishi I.
- Organizer
  International Conference on Cell Science and Molecular Biology (Cell Science-2021)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09840
[Presentation] Molecular Pathology of human uterine mesenchymal tumors.2021
- Author(s)
  Hayashi T. Ichimura T. Mandai M. Tonegawa S. Yaegasgi N. Konishi I.
- Organizer
  International Conference on Cancer Science: Research & Development (ICSR 2021).
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09840
[Presentation] Oncological Features of Intravenous Leiomyomatosis: Involvement of Mesenchymal Tumor Stem-Like Cells.2021
- Author(s)
  Tamura S. Hayashi T. Tokunaga H. Yaegashi N. Abiko K. Konishi I.
- Organizer
  Overcoming Therapy Resistance in Cancer Cell Symposia
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09840
[Presentation] LMP2/b1i as Tumor-suppressor Defines New Targets for Uterine Leiomyosarcoma Therapy.2020
- Author(s)
  Takuma Hayashi, Kenji Sano, Tomoki Ichimura, Kaoru Abiko, Ken Yamaguchi, Hiroyuki Aburatani, Susumu Tonegawa, Masaki Mandai, Nobuo Yaegashi, Ikuo Konishi.
- Organizer
  World Congress on Cancer and Diagnostics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09840
[Presentation] molecular pathological study of Gynecological cancer2020
- Author(s)
  Takuma Hayashi
- Organizer
  WORLD CONGRESS ON MEDICAL PATHOLOGY
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09840
[Presentation] Initialization of epithelial cells by tumor cells in a metastatic microenvironment.2020
- Author(s)
  Takuma Hayashi, Kenji Sano, Hiroyuki Aburatani, Nobuo Yaegashi, Ikuo Konishi.
- Organizer
  TARGETING THE TUMOR MICROENVIRONMENT TO COMBAT CANCER
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09840
[Presentation] Mice-lacking LMP2, immuno-proteasome subunit, as an animal model of spontaneous uterine leiomyosarcoma.2020
- Author(s)
  Takuma Hayashi
- Organizer
  The World Gene Convention-2020 (WGC-2020) conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09840
[Presentation] Zoonotic disease: A highly conserved binding region of ACE2 as receptor for SARS-CoV-2 between human and mammals.2020
- Author(s)
  Takuma Hayashi, Takashi Ura, Kaoru Abiko, Yasuaki Amano, Masaki Mandan, Nobuo Yaegashi, Ikuo Konishi.
- Organizer
  Infectious Diseases
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09840
[Presentation] 林琢磨.免疫組織学的バイオマーカーによる子宮間葉性腫瘍の予後予測法の確立に関する研究2019
- Author(s)
  Hayashi T, Ichimura T, Sano K, Tonegawa S, Kanai Y, Zharhary D, Aburatani H, Yaegashi N, Konishi I.
- Organizer
  2019年度、公益社団法人日本婦人科腫瘍学会
- Data Source
  KAKENHI-PROJECT-19K09840
[Presentation] LMP2/b1i as tumor-suppressor defines new targets for uterine leiomyosarcoma therapy.2019
- Author(s)
  Hayashi T, Ichimura T, Sano K, Tonegawa S, Kanai Y, Zharhary D, Aburatani H, Yaegashi N, Konishi I.
- Organizer
  3rd International Conrefence of Gynecology and Obsterestics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09840
[Presentation] Molecular pathological studies of Uterine Mesenchymal Tumor for Diagnosis and Therapy.2019
- Author(s)
  Hayashi T
- Organizer
  The 3rd International Conference on Gynecology, Obstetrics and Reproductive Medicine (GORM-BT 2019)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09840
[Presentation] 癌ゲノム医療の進展：婦人科腫瘍における癌ゲノム医療の確立に向けて2019
- Author(s)
  Hayashi T, Ichimura T, Sano K, Tonegawa S, Kanai Y, Zharhary D, Aburatani H, Yaegashi N, Konishi I.
- Organizer
  京都癌セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19K09840
[Presentation] LMP2/b1i as tumor-suppressor defines new targets for uterine leiomyosarcoma therapy.2019
- Author(s)
  Hayashi T, Ichimura T, Sano K, Aburatani H, Tonegawa S, Yaegashi N, Konishi I.
- Organizer
  17th Annual Cogress of International Drug Discovery Science and Technology.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09840
[Presentation] Potential roles of PSMB9/b1i and CAVEOLIN 1 define new targets for uterine leiomyosarcoma therapy. Clinical Application of Protein2017
- Author(s)
  Kawano M, Hayashi T, Shiozawa T, Ichimura T, Yaegashi N, Tonegawa S, Konishi I
- Organizer
  10th Anniversary of Protein & Peptide Conference
- Place of Presentation
  Fukuoka, Japan
- Year and Date
  2017-03-23
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10709
[Presentation] Potential roles of LMP2/b1i as negative regulator defines new targets for uterine leiomyosarcoma therapy2016
- Author(s)
  Hayashi T, Kawano M, Sano K, Ichimura T, Kasai M, Kanai Y, Aburatani H, Tonegawa S, Shiozawa T, Yaegashi N, Konishi I
- Organizer
  2016 International Conference on Biotechnology and Bioengineering (ICBB).
- Place of Presentation
  Bangkok, Thailand
- Year and Date
  2016-12-08
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10709
[Presentation] Potential roles of PSMB9/b1i and Caveolin 1 define new targets for uterine leiomyosarcoma2016
- Author(s)
  Hayashi T, Horiuchi A, Shiozawa T, Ishiko O, Yaegashi N, Tonegawa S, Konishi I
- Organizer
  57thJSCC/ICC2016,
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2016-05-29
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10709
[Presentation] Uterine Leiomyosarcoma Tumorigenesis in Lmp2-deficient Mice: Involvement of Impaired Anti-oncogenic Factor IRF1.2016
- Author(s)
  Hayashi T, Horiuchi A, Sano K, Yaegashi N, Konishi I.
- Organizer
  The 75th Annual Meeting of the Japanese Cancer Association. October 8, 2016.
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2016-10-07
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10709
[Presentation] Molecular approach of the sarcomagenesis of uterine mesenchymal tumours.2016
- Author(s)
  Hayashi T, Kanai Y, Kawano M, Osawa S, Aburatani H, Tonegawa S, Yaegashi N, Konishi I.
- Organizer
  World Congress of Cancer Research-2016.
- Place of Presentation
  Shanghai, China
- Year and Date
  2016-05-13
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10709
[Presentation] The ICOS-ligand B7-H2, expressed on human type II alveolar epithelial cells, plays a role in the pulmonary host defense system2016
- Author(s)
  Qian X, Freeman GJ, Tagawa Y-I, Hayashi T
- Organizer
  The Fifth Bizan Immunology Symposium at University of Tokushima. Immunology Program at the University of Tokushima (IPUT)
- Place of Presentation
  Tokushima University School of Medicine, Tokushima, Japan
- Year and Date
  2016-03-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10709
[Presentation] Potential role of LMP2 as negative regulator defines new targets for uterineleiomyosarcoma therapy2015
- Author(s)
  Hayashi T, Horiuchi A, Shiozawa T, Ishiko O, Yaegashi N, Tonegawa S, Konishi I
- Organizer
  5th World Congress on Cancer Research
- Place of Presentation
  Atlanta, USA
- Year and Date
  2015-09-28
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24592510
[Presentation] Potential roles of LMP2 and Caveolin 1 define new targets for uterine leiomyosarcoma therapy.2015
- Author(s)
  Hayashi T, Horiuchi A, Shiozawa T, Ishiko O, Yaegashi N, Tonegawa S, Konishi I
- Organizer
  FACO Internal Workshop, 3rd International Conference of Federation of Asian Clinical Oncology (FACO)
- Place of Presentation
  Kyoto International Hall, Kyoto, Japan
- Year and Date
  2015-10-29
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24592510
[Presentation] Preventive effect of ascorbic acid against Tat-dependent HIV-1 replication2015
- Author(s)
  Hayashi T, Young R.A.
- Organizer
  19th International Conference of FFC and 7th International Symposium of ASFFBC, Functional and Medical Foods, Bioactive Compounds and Biomarkers: Longevity and Quality of Life.
- Place of Presentation
  Kobe University, Kobe, Japan
- Year and Date
  2015-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24592510
[Presentation] Regenerative effect of Calcineurin inhibitor, Tacrolimus on Optic neuropathy2015
- Author(s)
  Hayashi T, Nakamura-Yanagidaira T, Hirano T, Murata T
- Organizer
  World Congress of Regenerative Medicine & Stem Cell-2015
- Place of Presentation
  Shanghai, China
- Year and Date
  2015-11-18
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10709
[Presentation] 子宮間葉系腫瘍に対する新規バイオマーカーの探索2014
- Author(s)
  林琢磨, 堀内晶子, 塩沢丹里, 石河修, 八重樫伸生, 利根川進, 小西郁生
- Organizer
  第2回婦人科がんバイオマーカー研究会学術集会
- Place of Presentation
  東京慈恵医科大学、港区、東京都
- Year and Date
  2014-07-05
- Invited
- Data Source
  KAKENHI-PROJECT-24592510
[Presentation] Potential role of LMP2 as negative regulator defines new targets for uterine leiomyosarcoma therapy2014
- Author(s)
  Hayashi T, Horiuchi A, Shiozawa T, Ishiko O, Yaegashi N, Tonegawa S, Konishi I
- Organizer
  第13回日本婦人科がん分子標的研究会
- Place of Presentation
  米子　皆生ホテル
- Data Source
  KAKENHI-PROJECT-24592510
[Presentation] 子宮平滑筋肉腫の生物学的特性：腫瘍能と老化2013
- Author(s)
  林　琢磨
- Organizer
  東北大学医学部統合産婦人科学研究コアセンターシンポジウム 2013
- Place of Presentation
  東北大学医学部　仙台
- Invited
- Data Source
  KAKENHI-PROJECT-24592510
[Presentation] Candidate molecules and ki-67/MIB1 as novel diagnostic biomarker for human uterine mesenchymal tumors.2013
- Author(s)
  Hayashi T, Horiuchi A, Tonegawa S, Konishi I.
- Organizer
  International Cession, Japan Cancer Association.
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24592510
[Presentation] 子宮間葉系腫瘍の鑑別に対する新規バイオマーカーの検討2013
- Author(s)
  林琢磨、堀内晶子、油谷浩幸、利根川進、小西郁生
- Organizer
  第１回婦人科がんバイオマーカー研究会学術集会
- Place of Presentation
  東京大学本郷キャンパス
- Data Source
  KAKENHI-PROJECT-24592510
[Presentation] Potential role of LMP2 as negative regulator defines new targets for uterine leiomyosarcoma therapy2013
- Author(s)
  Hayashi T, Horiuchi A, Shiozawa T, Ishiko O, Yaegashi N, Tonegawa S, Konishi I.
- Organizer
  第3回アジア婦人科腫瘍学会
- Place of Presentation
  ウェステイン都ホテル京都
- Invited
- Data Source
  KAKENHI-PROJECT-24592510
[Presentation] 子宮平滑筋肉腫の生物学的特徴：血行性転移でのLMP2の関与.子宮肉腫の基礎と臨床2013
- Author(s)
  林琢磨、堀内晶子、塩沢丹里、小西郁生
- Organizer
  第54回日本婦人科腫瘍学会
- Place of Presentation
  東京・お台場　LeDaibaホテル
- Invited
- Data Source
  KAKENHI-PROJECT-24592510
[Presentation] 子宮筋腫、異型筋腫および平滑筋肉腫の術前鑑別診断に関する検討2013
- Author(s)
  松田真希子、市村友季、村上誠、笠井真理、川村直樹、林琢磨、堀内晶子、角俊幸、石河修
- Organizer
  第54回日本婦人科腫瘍学会
- Place of Presentation
  東京・お台場　LeDaibaホテル
- Invited
- Data Source
  KAKENHI-PROJECT-24592510
[Presentation] 子宮平滑筋肉腫の生物学的特徴：血行性転移でのLMP2の関与2012
- Author(s)
  林　琢磨
- Organizer
  第20回日本血管生物医学学術総会
- Place of Presentation
  徳島県郷土文化会館
- Data Source
  KAKENHI-PROJECT-24592510
[Presentation] Potential role of LMP2 as tumor-suppressor defines new targets for uterine leiomyosarcoma therapy2012
- Author(s)
  Hayashi T, Horiuchi A, Shiozawa T, Tonegawa S, Konishi I
- Organizer
  第26回日本産婦人科学会学術講演会
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-24592510
[Presentation] Molecular mechanism of hematogenous metastasis of uterine leiomyosarcoma:involvement of biological significance of LMP22012
- Author(s)
  Takuma Hayashi, Akiko Horiuchi, Susumu Tonegawa, Ikuo Konishi
- Organizer
  World Cancer Congress 2012
- Place of Presentation
  Beijing
- Invited
- Data Source
  KAKENHI-PROJECT-24592510
[Presentation] 子宮平滑筋肉腫の腫瘍細胞浸潤と血行性転移における、LMP2の生物学的重要性の関与2012
- Author(s)
  Hayashi T, Horiuchi A, Shiozawa T, Tonegawa S, Konishi I
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市教育文化会館
- Data Source
  KAKENHI-PROJECT-24592510
[Presentation] 子宮平滑筋肉腫の生物学的特徴：血行性転移でのLMP2の関与2012
- Author(s)
  林　琢磨
- Organizer
  第21回日本がん転移学会学術集会
- Place of Presentation
  オリエンタルホテル広島
- Data Source
  KAKENHI-PROJECT-24592510
[Presentation] Tumor invasion and hematogenous metastasis of uterine leiomyosarcoma: involvement of biological significance of LMP22012
- Author(s)
  Hayashi T., Horiuchi A., Aburatani H., Tonegawa S., Konishi
- Organizer
  12th Korea-Japan Joint Symposium on Vascular Biology
- Place of Presentation
  Tokushima
- Data Source
  KAKENHI-PROJECT-24592510
[Presentation] 子宮平滑筋肉腫の生物学的応答性:ベンチワークからベッドサイトへ子宮筋層内膜症(特別講演)2011
- Author(s)
  林琢磨
- Organizer
  第51回婦人科腫瘍学会
- Place of Presentation
  福岡
- Year and Date
  2011-11-25
- Data Source
  KAKENHI-PROJECT-21592126
[Presentation] Potential role of LMP2 as tumor-suppressor defines new targets for uterine leiomyosarcoma therapy2011
- Author(s)
  Hayashi T, Horiuchi A, Shiozawa T, Tonegawa S, Konishi I
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(招待講演)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21592126
[Presentation] LMP2-Deficient mice as animal model of spontaneous uterine leiomyosarcoma for Development of Diagnosis and Anti-tumor Drug2011
- Author(s)
  Hayashi T, Horiuchi A, Shiozawa T, Tonegawa S, Konishi I
- Organizer
  シンポジウムWorld BiologicalMeeting
- Place of Presentation
  China
- Data Source
  KAKENHI-PROJECT-21592126
[Presentation] シンポジウム:婦人科がん治療標的探索の最前線:子宮平滑筋肉腫の細胞浸潤と血行性転移について:サイトカインとLMP2の関連性2010
- Author(s)
  林琢磨、堀内晶子、油谷浩幸、塩沢丹里、利根川進、小西郁生
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場(招待講演)
- Data Source
  KAKENHI-PROJECT-21592126
[Presentation] Establish ment of diagnostic biomarker against uterine leiomyosarcoma for Development of Diagnosis and Anti-tumor Drug2010
- Author(s)
  Hayashi T, Horiuchi A, Aburatani H, Shiozawa T, Tonegawa S and Konishi I
- Organizer
  International Cancer Meeting 2010
- Place of Presentation
  Singapore
- Data Source
  KAKENHI-PROJECT-21592126
[Presentation] Molecular mechanism on uterine leiomyosarcoma tumori genesis : LMP2 and Cell Clock Connection2010
- Author(s)
  林琢磨
- Organizer
  京都大学婦人科腫瘍学セミナー・京都大学がんプロフェショナル養成プラン
- Place of Presentation
  京都
- Year and Date
  2010-06-07
- Data Source
  KAKENHI-PROJECT-21592126
[Presentation] 子宮平滑筋肉腫の細胞浸潤と血行性転移について:サイトカインとLMP2の関連性、シンポジウム:婦人科がん治療標的探索の最前線2010
- Author(s)
  林琢磨、堀内晶子、油谷浩幸、塩沢丹里、利根川進、小西郁生
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21592126
[Presentation] LMP2とCyclin Eをバイオマーカーとした子宮平滑筋肉腫に対する新規診断法2009
- Author(s)
  Takuma Hayashi
- Organizer
  一般口演、創薬イノベーションフォーラム2009
- Place of Presentation
  東京、日本
- Year and Date
  2009-12-15
- Data Source
  KAKENHI-PROJECT-21592126
[Presentation] Established LMP2-Biomarker for Development of Diagnosis and Anti-tumor Drug against Uterine Leiomyosarcoma.2009
- Author(s)
  Takuma Hayashi
- Organizer
  シンポジウム2nd Annual Congress and Expo of Molecular Diagnostics(CEMD-2009)、国際会議招待講演
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-21592126
[Presentation] 子宮平滑筋肉腫の発症機序の解析と新規バイオマーカーを用いた診断法の確立2009
- Author(s)
  Takuma Hayashi
- Organizer
  東北大学病院がんセミナー・東北がんプロフェショナル養成プラン、依頼講演
- Place of Presentation
  仙台、日本
- Year and Date
  2009-07-16
- Data Source
  KAKENHI-PROJECT-21592126
[Presentation] Established LMP2-Biomarker for Development of Diagnosis and Anti-tumor Drug against Uterine Leiomyosarcoma.2009
- Author(s)
  Takuma Hayashi
- Organizer
  第68回日本癌学会(Workshop)
- Place of Presentation
  横浜、日本
- Data Source
  KAKENHI-PROJECT-21592126
[Presentation] 子宮平滑筋肉腫の血行性転移の分子生物学的解析: LMP2の発現の関与について2009
- Author(s)
  林琢磨、堀内晶子、小西郁生
- Organizer
  がん転移治療の最前線~臨床・創薬~、第18回日本がん転移学会学術集会総会
- Place of Presentation
  旭川
- Data Source
  KAKENHI-PROJECT-21592126
[Presentation] A novel diagnostic biomaker, LMP2, for human uterine leiomyosarcoma.2009
- Author(s)
  Takuma Hayashi
- Organizer
  一般口演、The 20th Asia Pacific Cancer Conference、国際会議
- Place of Presentation
  Tsukuba, Japan
- Data Source
  KAKENHI-PROJECT-21592126
[Presentation] 子宮平滑筋肉腫の発症機序の解析と新規バイオマーカーを用いた診断法の確立2009
- Author(s)
  林琢磨
- Organizer
  東北大学病院がんセミナー・東北がんプロフェショナル養成プラン
- Place of Presentation
  仙台
- Year and Date
  2009-07-16
- Data Source
  KAKENHI-PROJECT-21592126
[Presentation] Detection of somatic mutation on IFN-γ signaling pathway in Uterine Leiomyosarcoma2009
- Author(s)
  Kano H, Horiuchi A, Konishi I, Hayashi T
- Organizer
  第68回日本癌学会(Workshop)
- Place of Presentation
  横浜、日本
- Data Source
  KAKENHI-PROJECT-21592126
[Presentation] LMP2-Deficient Mice as Animal Model of Spontaneous Uterine Leiomyosarcoma for Development of Diagnosis and Anti-tumor Drug2009
- Author(s)
  Takuma Hayashi
- Organizer
  シンポジウムWorld Cancer Congress 2009国際会議、招待講演
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-21592126
[Presentation] LMP2-Deficient Mice as Animal Model of Spontaneous Uterine2009
- Author(s)
  Takuma Hayashi
- Organizer
  Leiomyosarcoma for Development of Diagnosis and Anti-tumor Drug World Cancer Congress 2009
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-21592126
[Presentation] 子宮平滑筋肉腫の血行性転移の分子生物学的解析:LMP2の発現の関与について2009
- Author(s)
  Takuma Hayashi
- Organizer
  シンポジウム、第18回日本がん転移学会学術集会総会、依頼講演
- Place of Presentation
  旭川、日本
- Data Source
  KAKENHI-PROJECT-21592126
[Presentation] Potential role of LMP2 as negative regulator defines new targets for uterine leiomyosarcoma therapy
- Author(s)
  Takuma Hayashi, Akiko Horiuchi, Ikuo Konishi
- Organizer
  Cell Symposium: Hallmarks of Cancer
- Place of Presentation
  ラッフルズ北京ホテル、北京、中国
- Year and Date
  2014-11-09 – 2014-11-11
- Data Source
  KAKENHI-PROJECT-24592510
[Presentation] 子宮平滑筋肉腫：造腫瘍化と老化
- Author(s)
  林琢磨, 堀内晶子, 塩沢丹里, 石河修, 八重樫伸生, 利根川進, 小西郁生
- Organizer
  第56回日本婦人科腫瘍学会
- Place of Presentation
  栃木県総合文化センター、宇都宮、栃木県
- Year and Date
  2014-07-17 – 2014-07-19
- Invited
- Data Source
  KAKENHI-PROJECT-24592510
[Presentation] Potential role of LMP2 as negative regulator defines new targets for uterine leiomyosarcoma therapy
- Author(s)
  Takuma Hayashi, Akiko Horiuchi, Tanri Shiozawa, Osamu Ishiko, Nobuo Yaegashi, Susumu Tonegawa, Ikuo Konishi
- Organizer
  第13回日本婦人科がん分子標的研究会
- Place of Presentation
  皆生グランドホテル天水、米子、鳥取県
- Year and Date
  2014-04-14 – 2014-04-15
- Data Source
  KAKENHI-PROJECT-24592510
[Presentation] Potential role of LMP2 as negative regulator defines new targets for uterine leiomyosarcoma therapy
- Author(s)
  Takuma Hayashi, Akiko Horiuchi, Tanri Shiozawa, Osamu Ishiko, Nobuo Yaegashi, Susumu Tonegawa, Ikuo Konishi
- Organizer
  第73回日本癌学会
- Place of Presentation
  パシフィコ横浜、横浜、神奈川県
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24592510

1. KONISHI Ikuo (90192062)

# of Collaborated Projects: 4 results

# of Collaborated Products: 72 results
2. SANO Kenji (50205994)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
3. SHIOZAWA Tanri (20235493)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
4. HORIUCHI Akiko (80334895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
5. YAEGASHI Nobuo (00241597)

# of Collaborated Projects: 1 results

# of Collaborated Products: 22 results
6. 安彦郁 (20508246)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 村上隆介 (40782363)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SUZUKI Akihisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. BABA Tsukasa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 田川陽一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HAYASHI TAKUMA 林 琢磨

Hayashi Takuma 林 琢磨

HAYASHI Takuma 林 琢磨

Research Projects

Research Products

Co-Researchers

Basic research for research and development of antitumor agents for intractable gynecologic tumors

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卵巣がんの発生初期の免疫微小環境に着目した腹膜播種機構の解明と新規治療法の開発

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Intractable disease: Construction of a foundation for research and development of new treatment methods for malignant uterine mesenchymal tumorsPrincipal Investigator

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Development of preoperative diagnosis using liquid biopsy for uterine leiomyosarcomaPrincipal Investigator

Principal Investigator

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Review Section

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婦人科悪性腫瘍に対する新規治療法の開発：子宮間葉系腫瘍の生物学的応答性の解析Principal Investigator

Principal Investigator

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Molecular approach of characterize of uterine leiomyosarcoma:development of novel therapy against uterine mesenchymal tumoursPrincipal Investigator

Principal Investigator

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Research Institution

Comparative analysis of stem cells between normal and neoplastic myometric cells

Principal Investigator

Project Period (FY)

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Research Institution

For development of a new therapeutic approach : Examination of biological response of uterine leiomyosarcoma in microenvironmentsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Molecular approach on autoimmune disease, IDDM (insulin dependent diabetes mellitus) expression, involvement of defective LMP2 expressionPrincipal Investigator

Principal Investigator

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Research Institution

[Book] Highly conserved binding region of ACE2 as a receptor for SARS-CoV-2 between humans and mammals2023

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[Book] Prime Archives in Molecular Biology 2nd Edition2021

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[Book] 末病と抗老化2020

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[Book] Precision Medicine in Gynecology and Obstetrics2017

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[Book] Current Research in Cancer2014

HAYASHI TAKUMA 林琢磨

Hayashi Takuma 林琢磨

HAYASHI Takuma 林琢磨