HATA Kenichiro 秦健一郎

Researcher Number	60360335
Other IDs
Affiliation (Current)	2024: 群馬大学, 大学院医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 群馬大学, 大学院医学系研究科, 教授 2022 – 2023: 国立研究開発法人国立成育医療研究センター, 周産期病態研究部, シニアフェロー 2015 – 2021: 国立研究開発法人国立成育医療研究センター, 周産期病態研究部, 部長 2015 – 2016: 国立研究開発法人国立成育医療研究センター, その他部局等, その他 2012 – 2016: 国立成育医療研究センター, 周産期病態研究部, 部長 … More 2015: 国立成育医療研究センター, 部長 2014: 独立行政法人国立成育医療研究センター, 周産期病態研究部, 部長 2012 – 2014: 独立行政法人国立成育医療研究センター, その他部局等, その他 2013: 国立成育医療研究センター, 部長 2012: 国立成育医療センター研究所, 周産期病態研究部, 部長 2011: 国立成育医療研究センター, 部長 2011: 国立成育医療研究センター, 研究所・周産期病態研究部, 部長 2010 – 2011: 国立成育医療研究センター研究所, 周産期病態研究部, 部長 2009 – 2011: National Research Institute for Child Health and Development, 周産期病態研究部, 部長 2008 – 2011: National Research Institute for Child Health and Development, 周産期病態研究部, 部長 2007: NRCHD, Maternal-Fetal Biology, Director 2007: National Research Institute for Child Health and Development, Director 2007: 国立育成医療センター(研究所), 周産期病態研究部, 部長 2006: 国立成育医療センター(研究所), 周産期病態研究部, 部長 2006: 国立成育医療センター, その他 2003 – 2005: 国立遺伝学研究所, 総合遺伝研究系, 助手 Less
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Human genetics / Biological Sciences / Basic Section 52050:Embryonic medicine and pediatrics-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Biomedical structure and function and related fields Except Principal Investigator Hygiene and public health / Obstetrics and gynecology / Embryonic/Neonatal medicine / Biological Sciences … More / Basic Section 56040:Obstetrics and gynecology-related / Psychiatric science / Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 52050:Embryonic medicine and pediatrics-related / Environmental physiology(including physical medicine and nutritional physiology) / Applied animal science / Biofunction/Bioprocess Less
Keywords	Principal Investigator エピジェネティクス / DNAメチル化 / エピゲノム / ゲノム / 遺伝学 / 発生・分化 / 生殖補助医療 / 生殖細胞 / ゲノムインプリンティング / DOHaD … More / 流産 / 胎盤 / 配偶子 / エピゲノム変異 / エピゲノム多型 / 環境因子 / ChILT法 / ChiLT法 / 網羅的エピゲノム解析 / 子宮内膜症 / 発生異常 / inferlity / epigenetics / DNA methyylation / aging / oocytes / 不妊症 / 老化 / 卵子 / 染色体診断 / 核型診断 / 一塩基多型 / TS細胞 / small RNA / 性分化 / エピジェネティスク / 遺伝子 / タンパク質相互作用 / 幹細胞 … More Except Principal Investigator GABA / DNAメチル化 / 発生・分化 / 妊娠期曝露 / 無機ヒ素 / 発達障害 / タウリン / 細胞移動 / エピジェネティクス / CRH / メチル化 / 精子 / インスリン感受性 / 妊娠糖尿病 / 継世代影響 / 胎児期曝露 / miRNA / F2影響 / 肝腫瘍 / トニックカレント / KCC2 / タウリントランスポーター / 母体ストレス / 大脳皮質 / 皮質板細胞 / エピゲノム / ゲノム / エピジェネティック修飾 / 迅速検出 / 構造変化 / ゲノムDNA / CpGメチル化 / アナフィラキシー / 羊水 / DIC / 遺伝子素因 / 全身型羊水塞栓症 / 子宮型羊水塞栓症 / 凝固異常 / 心肺虚脱 / アナフィラクトイド反応 / 遺伝子 / 遺伝子変異 / 免疫 / 妊娠 / 妊産婦死亡 / 危機的産科出血 / 消費石凝固障害 / 母体死亡 / ゲノム解析 / 羊水塞栓症 / 炎症性腸疾患 / 先天性貧血 / DoHaD / インスリン抵抗性 / 網羅的解析 / 臍帯血DNA / 糖代謝異常 / DOHaD仮説 / 新生児低血糖 / エピゲノム変化 / 臍帯血メチル化 / small RNA / tRNA fragment / piRNA / small RNA seq / 次世代影響 / 標的治療 / OMICS解析 / 婦人科腫瘍学 / 分子標的治療 / バイオマーカー / 次世代シーケンサー / 遺伝子発現解析 / DNAメチル化解析 / 染色体微細構造解析 / 子宮平滑筋肉腫 / 塩分負荷 / 低栄養 / GAD / コルチコステロン / WNK / 脳発達 / ストレス / 正中隆起 / 神経発生 / HPA / GAD67 / インスリン分泌 / 一塩基多型 / miiRNA / 発がん / エピ変異 / 脂質 / 脳・神経 / MEP50 / ゲノム不安定性 / 発現プロファイリング / 染色体ギャップ / SCAN / 新規遺伝子 / ZGA / 遺伝子発現パターン / 着床前期胚 / 生殖医学 / DNMT / 仮死モデル / 統合失調症 / 神経科学 / 生理学 / クロライドホメオダイナミクス / ＬＩＮ２８Ａ / ＲＮＡ結合タンパク質 / ＬＩＮ２８A / TS細胞 / RNA結合タンパク質 / LIN28A / 栄養膜幹細胞 / クロライドホメオスタシス / メチル化DNA結合蛋白質 / メチル化CpG / 簡易迅速検出 / メチル化頻度解析 / Znフィンガー蛋白質 / DNAのメチル化 / ゲノム刷り込み / ゲノム刷込み / 生殖細胞 / 発現制御 / ゲノムインプリンティング / 遺伝学 / 進化 Less

エピゲノム変異不均一性を指標にした初期胚・胎児期環境のエピゲノムへの影響評価Principal Investigator
- Principal Investigator
  
  秦健一郎
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Gunma University
Development of rapid detection method for CpG methylation of human genomic DNA based on the structural stability of DNAs
- Principal Investigator
  
  池袋一典
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Tokyo University of Agriculture and Technology
乳児に発症する炎症性腸疾患と造血不全の原因となる新たな単一遺伝子疾患の確立
- Principal Investigator
  
  竹内一朗
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  National Center for Child Health and Development
少数細胞エピゲノミクス技術を利用した子宮内膜症の網羅的エピゲノム解析Principal Investigator
- Principal Investigator
  
  秦健一郎
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Gunma University
  National Center for Child Health and Development
ヒト胎芽期・胎児期・新生児期の環境因子によるエピゲノム変異とその経時的変化の同定Principal Investigator
- Principal Investigator
  
  秦健一郎
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Gunma University
Genetic and pathophysiologic background of amniotic fluid embolism: In search of new intervention
- Principal Investigator
  
  伊東宏晃
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Hamamatsu University School of Medicine
Epigenetic changes in neonates born to Japanese mothers with gestational diabetes
- Principal Investigator
  
  Miyakoshi Kei
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Keio University
Omics-based analysis of specific biomarkers for leiomyosarcoma
- Principal Investigator
  
  Sonoda Kenzo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  National Hospital Organization, Kyushu Cancer Center
  Kyushu University
Screening for unknown factors of reproductive and developmental abnormalities from the viewpoint of epigenetic and/or genetic fragility.Principal Investigator
- Principal Investigator
  
  HATA KENCHIRO
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Biomedical structure and function and related fields
- Research Institution
  National Center for Child Health and Development
Identification of sperm small RNAs involved in multigenerational health effects of environmental chemicals
- Principal Investigator
  
  NOHARA Keiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene and public health
- Research Institution
  National Institute for Environmental Studies
Genome-wide DNA methylation analysis of sperm to explore the mechanism of hepatin tumor augmentation in the F2 by gestational arsenite exposure of F0 pregnant mice
- Principal Investigator
  
  Nohara Keiko
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hygiene and public health
- Research Institution
  National Institute for Environmental Studies
Studies on epimutations that are involved in multigenerational effects of environmental chemicals in mice
- Principal Investigator
  
  Nohara Keiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene and public health
- Research Institution
  National Institute for Environmental Studies
Verification of possible iatrogenic epimutations by artificial reproductive technologies.Principal Investigator
- Principal Investigator
  
  HATA KENICHIRO
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  National Center for Child Health and Development
Association of common polymorphisms with gestational diabetes mellitus in Japanese women
- Principal Investigator
  
  Miyakoshi Kei
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Keio University
Epitranscriptome in placentas of AGA and SGA babiesPrincipal Investigator
- Principal Investigator
  
  HATA KENCHIRO
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  National Center for Child Health and Development
Models for developmental disorder induced by interaction of maternal stress and fetal factors
- Principal Investigator
  
  Fukuda Atsuo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Hamamatsu University School of Medicine
molecular mechanisms of genomic rejuvenation during preimplantation development
- Principal Investigator
  
  HAMATANI TOSHIO
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Keio University
Embryonic lipid metabolism dysfunction as etiology of developmental disorder
- Principal Investigator
  
  MATSUZAKI Hideo
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Psychiatric science
- Research Institution
  University of Fukui
Multimodal GABA systems responding to environmental stress
- Principal Investigator
  
  Fukuda Atsuo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental physiology(including physical medicine and nutritional physiology)
- Research Institution
  Hamamatsu University School of Medicine
Studies on the role of LIN28A in mouse trophoblast stem cell
- Principal Investigator
  
  TANAKA Satoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Applied animal science
- Research Institution
  The University of Tokyo
Taurine abnormality may underlie developmental disorders via perturbation of multimodal GABA actions
- Principal Investigator
  
  FUKUDA Atsuo
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Hamamatsu University School of Medicine
common DNA methylation search of postmortem brain of individuals with schizophrenia and perinatal asphyxia-exposed rat model
- Principal Investigator
  
  TAKEI noriyoshi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Psychiatric science
- Research Institution
  Hamamatsu University School of Medicine
Development of the epoch-making chromosome diagnosis algorithm for the abnormal pregnanciesPrincipal Investigator
- Principal Investigator
  
  HATA Kenichiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  National Research Institute for Child Health and Development
Perturbation of developmental Cl^-homeodynamics may underlie fetal and neonatal brain disorders
- Principal Investigator
  
  FUKUDA Atsuo
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Hamamatsu University School of Medicine
Development of analysis method of methylation level using Zn finger protein
- Principal Investigator
  
  IKEBUKURO Kazunori
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Tokyo University of Agriculture and Technology
Identification of placenta specific small RNAPrincipal Investigator
- Principal Investigator
  
  HATA Kenichiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  National Research Institute for Child Health and Development
Mechanisms of epigenomic regulation in gametogenesis and genomic imprinting
- Principal Investigator
  
  SASAKI Hiroyuki
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
  National Institute of Genetics
哺乳類配偶子の雌雄差を規定する分子機構の解明Principal Investigator
- Principal Investigator
  
  秦健一郎
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Research Institute for Child Health and Development
Study of molecular mechanisms and controlling ofoocyte agingPrincipal Investigator
- Principal Investigator
  
  HATA Kenichiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  National Research Institute for Child Health and Development
哺乳類配偶子の雌雄差を規定する分子機構の解明Principal Investigator
- Principal Investigator
  
  秦健一郎
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Research Institute for Child Health and Development
  National Institute of Genetics
脊椎動物におけるエピジェネティクス機構の比較ゲノム解析
- Principal Investigator
  
  SASAKI Hiroyuki
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Genetics
生殖細胞の初期化と分化能を司るエピジェネティクス機構の解明Principal Investigator
- Principal Investigator
  
  秦健一郎
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Genetics
配偶子ゲノムの修飾機構と胚発生への影響
- Principal Investigator
  
  佐々木裕之
- Project Period (FY)
  2003 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Genetics
DNAメチル化インプリンティング確立に寄与する新規蛋白質の網羅的同定Principal Investigator
- Principal Investigator
  
  秦健一郎
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human genetics
- Research Institution
  National Institute of Genetics

[Book] 周産期遺伝カウンセリングマニュアル2017
- Author(s)
  佐村修、四元淳子、関沢明彦(編)、秦健一郎
- Total Pages
  194
- Publisher
  中外医学社
- ISBN
  9784498060777
- Data Source
  KAKENHI-PROJECT-26293365
[Book] エピジェネティクス2004
- Author(s)
  秦健一郎(分担)
- Total Pages
  238
- Publisher
  シュプリンガー・フェアラーク東京
- Data Source
  KAKENHI-PROJECT-15039234
[Book] エピジェネティクス2004
- Author(s)
  秦健一郎(分担)
- Total Pages
  238
- Publisher
  シュプリンガー・フェアラーク東京
- Data Source
  KAKENHI-PROJECT-15790173
[Journal Article] Reduced Representation Bisulfite Sequencing (RRBS).2023
- Author(s)
  Nakabayashi K, Yamamura M, Haseagawa K, Hata K
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 2577 Pages: 39-51
- DOI
  10.1007/978-1-0716-2724-2_3
- ISBN
  9781071627235, 9781071627242
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K19584, KAKENHI-PROJECT-23K24490
[Journal Article] Glucocorticoids increase the risk of preterm premature rupture of membranes possibly by inducing ITGA8 gene expression in the amnion2022
- Author(s)
  Okazaki Yuka、Taniguchi Kosuke、Miyamoto Yoshitaka、Kinoshita Shiori、Nakabayashi Kazuhiko、Kaneko Kayoko、Hamada Hiromi、Satoh Toyomi、Murashima Atsuko、Hata Kenichiro
- Journal Title
  
  Placenta
  
  Volume: 128 Pages: 73-82
- DOI
  10.1016/j.placenta.2022.07.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09587, KAKENHI-PROJECT-21H02887, KAKENHI-PROJECT-20K18182, KAKENHI-PROJECT-16KK0192, KAKENHI-PROJECT-23K24490
[Journal Article] 日本人の疾患と健康のためのバイオバンクとデータベース活用法　試料と情報の的確な探し方と使い方．(第5章)各疾患領域での実例　成育疾患研究におけるNCCHDバイオバンクの活用例2021
- Author(s)
  秦　健一郎
- Journal Title
  
  実験医学増刊
  
  Volume: 39 Pages: 1148-1151
- Data Source
  KAKENHI-PROJECT-21K19584
[Journal Article] Epigenetic Changes in Neonates Born to Mothers With Gestational Diabetes Mellitus May Be Associated With Neonatal Hypoglycaemia2021
- Author(s)
  Kasuga Yoshifumi、Kawai Tomoko、Miyakoshi Kei、Saisho Yoshifumi、Tamagawa Masumi、Hasegawa Keita、Ikenoue Satoru、Ochiai Daigo、Hida Mariko、Tanaka Mamoru、Hata Kenichiro
- Journal Title
  
  Frontiers in Endocrinology
  
  Volume: 12 Pages: 690648-690648
- DOI
  10.3389/fendo.2021.690648
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09761, KAKENHI-PROJECT-19K11735
[Journal Article] 【エピゲノムで新たな解明が進む「先天性疾患」】(第4章)周産期疾患・DOHaD　環境によるエピゲノムの変化と次世代への影響2021
- Author(s)
  秦　健一郎
- Journal Title
  
  遺伝子医学MOOK
  
  Volume: 36 Pages: 177-181
- Data Source
  KAKENHI-PROJECT-21K19584
[Journal Article] Is adjuvant therapy necessary for patients with intermediate-risk cervical cancer after open radical hysterectomy?2020
- Author(s)
  Hideaki Yahata, Kenzo Sonoda, Shusaku Inoue, Nobuko Yasutake, Keisuke Kodama, Hiroshi Yagi, Masafumi Yasunaga, Tatsuhiro Ohgami, Ichiro Onoyama, Eisuke Kaneki, Kaoru Okugawa, Kazuo Asanoma, Kiyoko Kato.
- Journal Title
  
  Oncology
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11281
[Journal Article] Retrospective analysis of treatment and prognosis for uterine leiomyosarcoma: 10‐year experience of a single institute2020
- Author(s)
  Kodama Keisuke、Sonoda Kenzo、Kijima Masako、Yamaguchi Shinichiro、Yagi Hiroshi、Yasunaga Masafumi、Ohgami Tatsuhiro、Onoyama Ichiro、Kaneki Eisuke、Okugawa Kaoru、Yahata Hideaki、Ohishi Yoshihiro、Oda Yoshinao、Kato Kiyoko
- Journal Title
  
  Asia-Pacific Journal of Clinical Oncology
  
  Volume: 16 Issue: 2 Pages: 63-67
- DOI
  10.1111/ajco.13286
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03800, KAKENHI-PROJECT-17K11281
[Journal Article] Safety evaluation of abdominal trachelectomy in patients with cervical tumors >2 cm: a single-institution, retrospective analysis.2020
- Author(s)
  Kaoru Okugawa, Hideaki Yahata, Kenzo Sonoda, Tatsuhiro Ohgami, Masafumi Yasunaga, Eisuke Kaneki, Kiyoko Kato.
- Journal Title
  
  Journal of Gynecologic Oncology
  
  Volume: 31 Issue: 4 Pages: 1-10
- DOI
  10.3802/jgo.2020.31.e41
- NAID
  120007044540
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11281, KAKENHI-PROJECT-19H03800
[Journal Article] Analysis of Chromosome Microstructures in Products of Conception Associated with Recurrent Miscarriage.2019
- Author(s)
  126.Sato T, Migita O, Hata H, Okamoto A, Hata K
- Journal Title
  
  Reprod Biomed Online
  
  Volume: 38 Issue: 5 Pages: 787-795
- DOI
  10.1016/j.rbmo.2018.12.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19535
[Journal Article] Pelvic abscess: a late complication of abdominal trachelectomy for cervical cancer.2019
- Author(s)
  Kaoru Okugawa, Kenzo Sonoda, Tatsuhiro Ohgami, Masafumi Yasunaga, Eisuke Kaneki, Hideaki Yahata, Kiyoko Kato.
- Journal Title
  
  The Journal of Obstetrics and Gynaecology Research
  
  Volume: 45 Issue: 2 Pages: 412-416
- DOI
  10.1111/jog.13814
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11281
[Journal Article] Survey of the desire to have children and engage in sexual activity after trachelectomy among young Japanese women with early-stage cervical cancer.2019
- Author(s)
  3.Yahata H, Sonoda K, Okugawa K, Yagi H, Yasunaga M, Ohgami T, Onoyama I, Kaneki E, Asanoma K, Kato K.
- Journal Title
  
  J Obstet Gynaecol Res.
  
  Volume: 45 Issue: 11 Pages: 2255-2259
- DOI
  10.1111/jog.14099
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09804, KAKENHI-PROJECT-19H03800, KAKENHI-PROJECT-17K11280, KAKENHI-PROJECT-17K11281
[Journal Article] Prognostic outcome and complications of sentinel lymph node navigation surgery for early-stage cervical cancer.2018
- Author(s)
  Hideaki Yahata, Hiroaki Kobayashi, Kenzo Sonoda, Keisuke Kodama, Hiroshi Yagi, Masafumi Yasunaga, Tatsuhiro Ohgami, Ichiro Onoyama, Eisuke Kaneki, Kaoru Okugawa, Shingo Baba, Takuro Isoda, Yoshihiro Ohishi, Yoshinao Oda, Kiyoko Kato.
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 23 Issue: 6 Pages: 1167-1172
- DOI
  10.1007/s10147-018-1327-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11281
[Journal Article] The DNA methylation profile of liver tumors in C3H mice and identification of differentially methylated regions involved in the regulation of tumorigenic genes.2018
- Author(s)
  Matsushita J, Okamura K, Nakabayashi K, Suzuki T, Horibe Y, Kawai T, Sakurai T, Yamashita S, Higami Y, Ichihara G, Hata K, Nohara K
- Journal Title
  
  BMC Cancer
  
  Volume: 18 Issue: 1 Pages: 317-317
- DOI
  10.1186/s12885-018-4221-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293365, KAKENHI-PLANNED-17H06396, KAKENHI-PROJECT-16H02965, KAKENHI-PROJECT-15K07697, KAKENHI-ORGANIZER-17H06391
[Journal Article] Two types of small cell carcinoma of the ovary: Two typical case reports.2018
- Author(s)
  Yu Yoshida, Eisuke Kaneki, Masako Kijima, Keisuke Kodama, Shinichiro Yamaguchi, Hiroshi Yagi, Masafumi Yasunaga, Tatsuhiro Ohgami, Ichiro Onoyama, Hideaki Yahata, Kenzo Sonoda, Kiyoko Kato.
- Journal Title
  
  Gynecologic Oncology Reports
  
  Volume: 25 Pages: 125-130
- DOI
  10.1016/j.gore.2018.07.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11281
[Journal Article] Infertility after abdominal trachelectomy.2018
- Author(s)
  Katsuko Egashira, Kana Hiasa, Natsuko Yokota, Teruhiko Kawamura, Chihiro Minami, Kaoru Okugawa, Hideaki Yahata, Kenzo Sonoda, Kiyoko Kato.
- Journal Title
  
  Acta Obstetricia et Gynecologica Scandinavica
  
  Volume: 97 Issue: 11 Pages: 1358-1364
- DOI
  10.1111/aogs.13429
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11281, KAKENHI-PROJECT-18K19618
[Journal Article] Value of intraoperative cytological and pathological sentinel lymph node diagnosis in fertility-sparing trachelectomy for early-stage cervical cancer.2018
- Author(s)
  Kenzo Sonoda, Hideaki Yahata, Kaoru Okugawa, Eisuke Kaneki, Tatsuhiro Ohgami, Masafumi Yasunaga, Shingo Baba, Yoshinao Oda, Hiroshi Honda, Kiyoko Kato.
- Journal Title
  
  Oncology
  
  Volume: 94 Issue: 2 Pages: 92-98
- DOI
  10.1159/000484049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11281
[Journal Article] Surgical treatment and outcome of early invasive adecarcinoma of the uterine cervix(FIGO stage lA1)2017
- Author(s)
  Yahata H, Sonoda K, Yasuaga K, Ohgami T, Kawano Y, Kaneki E, Okugawa K, Kaku T, Kato K
- Journal Title
  
  Asia-Pac J Clin Oncol
  
  Volume: 印刷中 Issue: 2 Pages: 1-4
- DOI
  10.1111/ajco.12691
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08378, KAKENHI-PROJECT-17K11281
[Journal Article] 環境因子のヒト発生への影響　エピゲノムの「乱れ」の観点から2017
- Author(s)
  河合智子，秦健一郎
- Journal Title
  
  Medical Science Digest
  
  Volume: 43 Pages: 592-596
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293365
[Journal Article] 新生児医療　最新トピックNEXT(no.7)　周産期医療におけるエピジェネティクスの展望2017
- Author(s)
  右田王介，秦健一郎
- Journal Title
  
  Neonatal Care
  
  Volume: 30 Pages: 953-953
- Data Source
  KAKENHI-PROJECT-17K19535
[Journal Article] Isthmic-vaginal cytological findings after trachelectomy for early-stage cervical cancer.2017
- Author(s)
  Kenzo Sonoda, Hideaki Yahata, Kaoru Okugawa, Eisuke Kaneki, Kanako Nakatsuki, Masaki Naka, Nobuyoshi Terado, Fumihiko Ookubo, Yoshinao Oda, Tsunehisa Kaku, Kiyoko Kato.
- Journal Title
  
  Cytopathology
  
  Volume: 28 Issue: 3 Pages: 243-245
- DOI
  10.1111/cyt.12379
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11281
[Journal Article] Oncologic and obstetrical outcomes and complications during pregnancy after fertility-sparing abdominal trachelectomy for cervical cancer: a retrospective review.2017
- Author(s)
  Kaoru Okugawa, Hiroaki Kobayashi, Kenzo Sonoda, Eisuke Kaneki, Yoshiaki Kawano, Nobuhiro Hidaka, Katsuko Egashira, Yasuyuki Fujita, Hideaki Yahata, Kiyoko Kato.
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 22 Issue: 2 Pages: 340-346
- DOI
  10.1007/s10147-016-1059-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11281
[Journal Article] Association of common polymorphisms with gestational diabetes mellitus in Japanese women: A case-control study2017
- Author(s)
  Kasuga, Y. Hata, K. Tajima, A. Ochiai, D. Saisho, Y. Matsumoto, T. Arata, N. Miyakoshi, K. Tanaka, M.
- Journal Title
  
  Endocr J
  
  Volume: 64 Issue: 4 Pages: 463-475
- DOI
  10.1507/endocrj.EJ16-0431
- NAID
  130005630406
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462500, KAKENHI-PROJECT-15K09724, KAKENHI-PROJECT-15H04320, KAKENHI-PROJECT-17H04236
[Journal Article] CTCF deletion syndrome: Clinical features and epigenetic delineation2017
- Author(s)
  Hori I, Kawamura R, Nakabayashi K, Watanabe H, Higashimoto K, Tomikawa J, Ieda D, Ohashi K, Negishi Y, Hattori A, Sugio Y, Wakui K, Hata K, Soejima H, Kurosawa K, Saitoh S
- Journal Title
  
  Journal of Medical Genetics
  
  Volume: 54 Issue: 12 Pages: 836-842
- DOI
  10.1136/jmedgenet-2017-104854
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07248, KAKENHI-PROJECT-17K08687, KAKENHI-PROJECT-26293365, KAKENHI-PROJECT-15K08330
[Journal Article] Reproductive/Developmental Abnormalities Induced by Epigenetic Aberrations and Possible Environmental Causes.2016
- Author(s)
  Kawai T, Hata K
- Journal Title
  
  Nihon Eiseigaku Zasshi
  
  Volume: 71 Pages: 195-199
- NAID
  130005264941
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293365
[Journal Article] Augmenting effects of gestational arsenite exposure of C3H mice on the hepatic tumors of the F2 male offspring via the F1 male offspring.2016
- Author(s)
  Nohara K, Okamura K, Suzuki T, Murai H, Ito T, Shinjo K, Takumi S, Michikawa T, Kondo Y, Hata K
- Journal Title
  
  J Appl Toxicol
  
  Volume: 36 Pages: 105-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670734
[Journal Article] Increased epigenetic alterations at the promoters of transcriptional regulators following inadequate maternal gestational weight gain2015
- Author(s)
  17.Kawai T, Yamada T, Abe K, Okamura K, Kamura H, Akaishi R, Minakami H, Nakabayashi K, Hata K
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Pages: 14224-14224
- Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293365
[Journal Article] Compilation of copy number variants identified in phenotypically normal and parous Japanese women.2014
- Author(s)
  19.Migita O, Maehara K, Kamura H, Miyakoshi K, Tanaka M, Morokuma S, Fukushima K, Shimamoto T, Saito S, Sago H, Nishihama K, Abe K, Nakabayashi K, Umezawa A, Okamura K, Hata K
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 59 Pages: 326-331
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24659742
[Journal Article] Compilation of copy number variants identified in phenotypically normal and parous Japanese women.2014
- Author(s)
  Migita O, Maehara K, Kamura H, Miyakoshi K, Tanaka M, Morokuma S, Fukushima K, Shimamoto T, Saito S, Sago H, Nishihama K, Abe K, Nakabayashi K, Umezawa A, Okamura K, Hata K
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 59 Pages: 326-331
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293365
[Journal Article] Development of a Method To Measure DNA Methylation Levels by Using Methyl CpG-Binding Protein and Luciferase-Fused Zinc Finger Protein.2012
- Author(s)
  Hiraoka D, Yoshida W, Abe K, Wakeda H, Hata K, Ikebukuro K.
- Journal Title
  
  Anal Chem.
  
  Volume: 84 Pages: 8259-8264
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659742
[Journal Article] 胎盤形成のエピジェネティクス2011
- Author(s)
  秦健一郎
- Journal Title
  
  臨床産婦人科
  
  Volume: 65 Pages: 243-247
- NAID
  10031166251
- Data Source
  KAKENHI-PROJECT-21590364
[Journal Article] Dynamic stage-specific changes of imprinted differentially methylated regions during early mammalian development and prevalence of non-CpG methylation in oocytes2011
- Author(s)
  Tomizawa, S., Kobayashi, H., Watanabe, T., Andrews, S., Hata, K., Kelsey, G. & Sasaki, H
- Journal Title
  
  Development
  
  Volume: 138 Issue: 5 Pages: 811-820
- DOI
  10.1242/dev.061416
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062010
[Journal Article] Dynamic stage-specific changes of imprinted differentially methylated regions during early mammalian development and prevalence of non-CpGmethylation in oocytes.2011
- Author(s)
  Tomizawa, S, Kobayashi, H, Watanabe, T, Andrews, S, Hata, K, Kelsey, G, Sasaki, H.
- Journal Title
  
  Development 138
  
  Pages: 811-829
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062010
[Journal Article] Histone methylation is mechanistically linked to DNA methylation at imprinting control regions in mammals2009
- Author(s)
  Henckel, A., Nakabayashi, K., Sanz, LA., Feil, R., Hata, K. & Arnaud, P
- Journal Title
  
  Hum Mol Genet
  
  Volume: 18 Issue: 18 Pages: 3375-83
- DOI
  10.1093/hmg/ddp277
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062010
[Journal Article] The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline2009
- Author(s)
  Shoji, M., Tanaka, T., Hosokawa, M., Reuter, M., Stark, A., Kato, Y., Kondoh, G., Okawa, K., Chujo, T., Suzuki, T., Hata, K., Martin, S.L., Noce, T., Kuramochi-Miyagawa, S., Nakano, T., Sasaki, H., Pillai, R.S., Nakatsuji, N. & Chuma, S
- Journal Title
  
  Dev. Cell
  
  Volume: 17 Pages: 775-787
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062010
[Journal Article] Abnormal DNA methyltransferase expression in mouse germline Stem Cells results in spermatogenic defects2009
- Author(s)
  Takashima, S.,Takehashi, M.,Lee, J., Chuma, S., Okano, M., Hata, K., Suetake, I., Nakatsuji, N.,Miyoshi, H., Tajima, S., Sasaki, H., Kanatsu-Shinohara, M. and Shinohara, T
- Journal Title
  
  Biol. Reprod
  
  Volume: 81 Issue: 1 Pages: 155-164
- DOI
  10.1095/biolreprod.108.074708
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062006, KAKENHI-PLANNED-20062010
[Journal Article] The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mousemale germline2009
- Author(s)
  Shoji, M, Tanaka, T, Hosokawa, M, Reuter, M, Stark, A, Kato, Y, Kondoh, G, Okawa, K, Chujo, T, Suzuki, T, Hata, K, Martin, SL, Noce, T, Kuramochi-Miyagawa, S, Nakano, T, Sasaki, H, Pillai, RS, Nakatsuji, N, Chuma, S.
- Journal Title
  
  Dev Cell 17
  
  Pages: 775-787
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062010
[Journal Article] Identification of the mouse paternally expressed imprinted gene Zdbf2 on chromosome 1 and its imprinted human homolog ZDBF2 on chromosome 22009
- Author(s)
  Kobayashi H, Yamada K, Morita S, Hiura H, Fukuda A, Kagami M, Ogata T, Hata K, Sotomaru Y, Kono T
- Journal Title
  
  Genomics
  
  Volume: 93(5) Issue: 5 Pages: 461-47
- DOI
  10.1016/j.ygeno.2008.12.012
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062009, KAKENHI-PLANNED-20062010
[Journal Article] DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes.2008
- Author(s)
  Kuramochi-Miyagawa, S, Watanabe, T, Gotoh, K, Totoki, Y, Toyoda, A, Ikawa, M, Asada, N, Kojima, K, Yamaguchi, Y, Ijiri, T, Hata, K, Li, E, Matsuda, Y, Kimura, T, Okabe, M, Sakaki, Y, Sasaki, H, Nakano, T.
- Journal Title
  
  Genes Dev 22
  
  Pages: 908-917
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062010
[Journal Article] DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes2008
- Author(s)
  Kuramochi-Miyagawa, S., Watanabe, T., Gotoh, K., Totoki, Y., Toyoda, A., Ikawa, M., Asada, N., Kojima, K., Yamaguchi, Y., Ijiri, T., Hata, K., Li, E., Matsuda, Y., Kimura, T., Okabe, M., Sakaki, Y., Sasaki, H. & Nakano, T
- Journal Title
  
  Genes Dev
  
  Volume: 22 Issue: 7 Pages: 908-917
- DOI
  10.1101/gad.1640708
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062010
[Journal Article] Meiotic and epigenetic aberrations in Dnmt3L-deficient male germ cells.2006
- Author(s)
  Hata, K.et al.
- Journal Title
  
  Mol.Reprod.Dev. 73
  
  Pages: 116-122
- Data Source
  KAKENHI-PROJECT-15080208
[Journal Article] Meiotic and epigenetic aberrations in Dnmt3L-deficient male germ cells.2006
- Author(s)
  Hata, K.et al.
- Journal Title
  
  Mol.Reprod.Dev. 73
  
  Pages: 116-122
- Data Source
  KAKENHI-PROJECT-17052026
[Journal Article] Meiotic and epigenetic aberrations in Dnmt3L-deficient male germ cells.2006
- Author(s)
  Hata K, et. al.
- Journal Title
  
  Mol Reprod Dev 73
  
  Pages: 116-122
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590316
[Journal Article] Meiotic and epigenetic aberrations in Dnmt3L-deficient male germ cells.2006
- Author(s)
  Hata K, et al.
- Journal Title
  
  Mol Reprod Dev 73
  
  Pages: 116-122
- Data Source
  KAKENHI-PROJECT-17052026
[Journal Article] Meiotic and epigenetic aberrations in Dnmt3L-deficient male germ cells.2006
- Author(s)
  Hata K, et al.
- Journal Title
  
  Mol Reprod Dev 73
  
  Pages: 116-122
- Data Source
  KAKENHI-PROJECT-18590316
[Journal Article] X-inactivation is stably maintained in mouse embryos deficient for histone methyltransferase G9a2004
- Author(s)
  Ohata, T., et al.
- Journal Title
  
  Genesis 40
  
  Pages: 151-156
- Data Source
  KAKENHI-PROJECT-15080208
[Presentation] 羊水塞栓症発症リスク因子としての遺伝子バリアントの解析2022
- Author(s)
  東堂祐介, 小田智昭, 中林一彦, 宗修平, 井出瑠衣, 田村直顕, 秦健一郎, 伊東宏晃
- Organizer
  日本産科婦人科学会
- Data Source
  KAKENHI-PROJECT-20H03823
[Presentation] 希少遺伝性疾患ゲノム診断率向上に向けてのDNAメチル化キャプチャーシーケンス法の開発．2022
- Author(s)
  4.長谷川慶太，中林一彦，河合智子，青砥早希，春日義史，副島英伸，岡本伸彦，田中守，秦健一郎
- Organizer
  日本人類遺伝学会
- Data Source
  KAKENHI-PROJECT-21H02887
[Presentation] 不妊・不育症リスク因子としての慢性子宮内膜炎のトランスクリプトーム解析．2021
- Author(s)
  大科恭子，中林一彦，黒田恵司，北出真理，板倉敦夫，秦健一郎
- Organizer
  日本人類遺伝学会第66回大会・第28回日本遺伝子診療学会大会
- Data Source
  KAKENHI-PROJECT-21K19584
[Presentation] Well-controlled gestational diabetes eliminates DNA methylation changes in cord blood cells associated with hyperglycemia and metabolic disorders in neonates.2019
- Author(s)
  Kasuga Y, Kawai T, Miyakoshi K, Tanaka M, Hata K
- Organizer
  DOHaD 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09761
[Presentation] Small RNA sequencingを用いた妊娠期無機ヒ素曝露による子世代精子で変化するtRNA fragmentsの探索2019
- Author(s)
  岡村和幸，中林一彦，石渡啓介，鈴木武博，秦健一郎，野原恵子
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H04139
[Presentation] The correlation between epigenetic change and neonatal plasma glucose level in maternal gestational diabetes offspring2019
- Author(s)
  Kasuga Y, Kawai T, Miyakoshi K, Hata K, Tanaka M
- Organizer
  RCOG World Congress 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09761
[Presentation] Accurate prediction of chromatin conformation status using deep neural network model.2018
- Author(s)
  Uryu H and Hata K
- Organizer
  Human Genome Meeting 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293365
[Presentation] Retrospective analysis on clinicopathological variables and prognosis of patients diagnosed as cervical cancer within 6 months after parturition.2018
- Author(s)
  Kenzo Sonoda, Tatsuhiro Ohgami, Masako Kijima, Keisuke Kodama, Masahiro Hachisuga, Shinichiro Yamaguchi, Hiroshi Yagi, Masafumi Yasunaga, Ichiro Onoyama, Hironori Kenjo, Eisuke Kaneki, Kaoru Okugawa, Yasuyuki Fujita, Hideaki Yahata, Kiyoko Kato.
- Organizer
  17th Biennial Meeting of the International Gynecologic Cancer Society.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11281
[Presentation] Oncological and obstetric management of women diagnosed with cervical cancer during pregnancy.2018
- Author(s)
  Kenzo Sonoda, Tatsuhiro Ohgami, Masako Kijima, Keisuke Kodama, Masahiro Hachisuga, Shinichiro Yamaguchi, Hiroshi Yagi, Masafumi Yasunaga, Ichiro Onoyama, Hironori Kenjo, Eisuke Kaneki, Kaoru Okugawa, Yasuyuki Fujita, Hideaki Yahata, Kiyoko Kato.
- Organizer
  第56回日本癌治療学会
- Data Source
  KAKENHI-PROJECT-17K11281
[Presentation] 妊娠期無機ヒ素曝露による孫世代（F2）の肝腫瘍増加に関与する仔世代（F1）精子のエピゲノム変化2018
- Author(s)
  野原恵子、岡村和幸、鈴木武博、中林一彦、秦健一郎
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H04139
[Presentation] Genetic and epigenetic analysis of the placenta2018
- Author(s)
  Kenichiro Hata
- Organizer
  International Federation of Placenta Associations
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19535
[Presentation] 「『ARTとDOHaDの相互理解と将来への展望』-生命誕生とエピジェネティクス」2017
- Author(s)
  秦健一郎
- Organizer
  第35回日本受精着床学会総会・学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-26293365
[Presentation] Maternal stress causes loss of parvalbumin neurons and alterations of extracellular glycans in the mPFC of GAD67-GFP knock-in mouse.2017
- Author(s)
  Wang T, Sinha adya S, Yanagawa Y, Hata K and Fukuda A.
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松（静岡県・浜松市）
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-26670512
[Presentation] DNA methylation changes derived from assisted reproductive technologies on human spontaneous miscarriage.2017
- Author(s)
  久須美真紀，河合智子，嘉村浩美，堤治，秦健一郎
- Organizer
  日本人類遺伝学会第62回大会
- Data Source
  KAKENHI-PROJECT-17K19535
[Presentation] Novel DNA methylation changes induced by gestational arsenite exposure in hepatic tumors in F2 mice.2016
- Author(s)
  岡村和幸、中林一彦、堀部悠、河合智子、鈴木武博、秦健一郎、野原恵子
- Organizer
  第5回日本DOHaD研究会学術集会
- Place of Presentation
  国立成育医療研究センター（東京）
- Year and Date
  2016-07-23
- Data Source
  KAKENHI-PROJECT-26293154
[Presentation] Common polymorphisms with gestational diabetes mellitus in Japanese women2016
- Author(s)
  Kasuga, Y. Miyakoshi, K. Hata, K. Tajima, A. Ikenoue, S. Ochiai, D. Matsumoto, T. Arata, N. Tanaka, M.
- Organizer
  The 19th Congress of the Federation of Asia and Oceania Perinatal Societies
- Place of Presentation
  Taipei International Convention Center, Taipei
- Year and Date
  2016-12-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462500
[Presentation] Association analysis of polymorphisms with high-risk group of gestational diabetes mellitus in a Japanese population2016
- Author(s)
  Kasuga Y, Hata K, Miyakoshi K, Otani T, Akiba Y, Fukutake M, Ochiai D, Matsumoto T, Arata T, Tajima A, Tanaka M, Aoki D
- Organizer
  第68回日本産科婦人科学会総会・学術講演会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-26462500
[Presentation] C3HマウスにおいてDNAメチル化変化を介して肝腫瘍形成に関与する遺伝子の探索2016
- Author(s)
  松下隼也、岡村和幸、鈴木武博、中林一彦、堀部悠、河合智子、秦健一郎、桜井敏博、市原学、野原恵子
- Organizer
  第10回日本エピジェネティクス研究会
- Place of Presentation
  千里ライフサイエンスセンター（大阪）
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-26293154
[Presentation] Prenatal stress causes loss of GABAergic interneurons and perineuronal nets in the cerebral cortex of GAD67-GFP knock-in mouse offspring.2016
- Author(s)
  Fukuda A, Wang T, Yanagawa Y, Kawai T and Hata K.
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-07-21
- Data Source
  KAKENHI-PROJECT-26670512
[Presentation] ヒト生殖・発生異常のゲノムとエピゲノム　-胎児期の環境による疾病素因形成のメカニズム-2016
- Author(s)
  秦健一郎
- Organizer
  第３９回高血圧学会
- Place of Presentation
  仙台
- Invited
- Data Source
  KAKENHI-PROJECT-26293365
[Presentation] Association analysis of polymorphisms with high-risk group of gestational diabetes mellitus in a Japanese population2016
- Author(s)
  Kasuga, Y. Hata, K. Miyakoshi, K. Ohtani, T. Akiba, Y. Fukutake, M. Ochiai, D. Matsumoto, T. Arata, T. Tajima, A. Tanaka, M. Aoki, D.
- Organizer
  第68回日本産科婦人科学会総会・学術講演会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-26462500
[Presentation] The Polymorphism in KCNQ1 gene may influence insulin secretion in Japanese pregnant women.2016
- Author(s)
  Kasuga Y, Miyakoshi K, Arata N, Tajima A, Tanaka M, Hata K.
- Organizer
  The 63th Annual Scientific Meeting of Society for Reproductive Investigation
- Place of Presentation
  モントリオール（カナダ）
- Year and Date
  2016-03-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462500
[Presentation] 周産期におけるゲノム・エピゲノム解析の応用2015
- Author(s)
  秦健一郎
- Organizer
  日本周産期・新生児医学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-07-12
- Invited
- Data Source
  KAKENHI-PROJECT-26293365
[Presentation] QTL解析を用いた日本人妊娠糖尿病関連候補遺伝子の検討.2015
- Author(s)
  春日義史、秦健一郎、宮越敬、福武麻里絵、正木繭、池ノ上学、落合大吾、松本直、荒田尚子、田中守
- Organizer
  第39回日本産科婦人科栄養代謝研究会
- Place of Presentation
  東京医科歯科大学　鈴木章夫記念講堂（東京都文京区）
- Year and Date
  2015-08-21
- Data Source
  KAKENHI-PROJECT-26462500
[Presentation] Common polymorphisms associated with gestational diabetes mellitus in Japanese women2015
- Author(s)
  Kasuga Y, Miyakoshi K, Saisho Y, Fukutake M, Ikenoue S, Ochiai D, Matsumoto T, Minegishi K, Maehara K, Hata K, Tanaka M
- Organizer
  International DIP symposium on Diabetes, Hypertension, metabolic syndrome & pregnancy
- Place of Presentation
  ベルリン（ドイツ）
- Year and Date
  2015-04-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462500
[Presentation] 生殖と発生異常にかかわるエピゲノム変化と環境の影響2015
- Author(s)
  秦健一郎
- Organizer
  日本衛生学会
- Place of Presentation
  和歌山
- Year and Date
  2015-03-26
- Invited
- Data Source
  KAKENHI-PROJECT-26670734
[Presentation] 日本人妊娠糖尿病の分子遺伝学的病態解析2015
- Author(s)
  春日義史、秦健一郎、宮越敬、福武麻里絵、正木繭、池ノ上学、落合大吾、松本直、峰岸一宏、前原佳代子、田中守、青木大輔
- Organizer
  第67回日本産科婦人科学会総会・学術講演会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2015-04-09
- Data Source
  KAKENHI-PROJECT-26462500
[Presentation] 胎児・胎盤発生異常のジェネティクスとエピジェネティクス2014
- Author(s)
  秦健一郎
- Organizer
  北関東遺伝診療フォーラム
- Place of Presentation
  大宮
- Year and Date
  2014-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-24659742
[Presentation] 生殖・周産期のエピジェネティクス2014
- Author(s)
  秦健一郎
- Organizer
  日本内分泌学会学術総会
- Place of Presentation
  福岡
- Year and Date
  2014-04-27
- Invited
- Data Source
  KAKENHI-PROJECT-26293365
[Presentation] 胎児と胎盤発生異常のエピジェネティクス2014
- Author(s)
  秦健一郎
- Organizer
  日本母体胎児医学会学術集会
- Place of Presentation
  佐世保
- Year and Date
  2014-11-07
- Invited
- Data Source
  KAKENHI-PROJECT-26293365
[Presentation] 発育不全とエピジェネティクス群馬大学生体調節研究所内分泌2012
- Author(s)
  秦健一郎
- Organizer
  代謝学共同研究拠点シンポジウム
- Place of Presentation
  前橋
- Year and Date
  2012-01-12
- Data Source
  KAKENHI-PROJECT-21590364
[Presentation] 次世代遺伝子解析技術を用いた生殖発生異常のゲノム研究2012
- Author(s)
  秦健一郎
- Organizer
  第30回日本受精着床学会学術講演会
- Place of Presentation
  大阪国際会議場(グランキューブ大阪)(招待講演)
- Year and Date
  2012-08-31
- Data Source
  KAKENHI-PLANNED-20062010
[Presentation] 次世代遺伝子解析技術を用いた生殖発生異常のゲノム研究2012
- Author(s)
  秦健一郎
- Organizer
  日本受精着床学会学術講演会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-24659742
[Presentation] 発育不全とエピジェネティクス2012
- Author(s)
  秦健一郎
- Organizer
  群馬大学生体調節研究所内分泌・代謝学共同研究拠点シンポジウム
- Place of Presentation
  前橋市
- Year and Date
  2012-01-12
- Data Source
  KAKENHI-PROJECT-21590364
[Presentation] ジェネティクスを越えてエピジェネティクスへ-周産期のエピジェネティクス2011
- Author(s)
  秦健一郎
- Organizer
  遺伝医学合同学術集会2011
- Place of Presentation
  京都
- Year and Date
  2011-06-17
- Data Source
  KAKENHI-PROJECT-21590364
[Presentation] ジェネティクスを越えてエピジェネティクスへ-周産期のエピジェネティクス2011
- Author(s)
  秦健一郎
- Organizer
  遺伝医学合同学術集会
- Place of Presentation
  京都
- Year and Date
  2011-06-17
- Data Source
  KAKENHI-PROJECT-21590364
[Presentation] 磁性ビーズを用いたDNAメチル化レベル評価法の開発2011
- Author(s)
  平岡大介、吉田亘、秦健一郎、池袋一典
- Organizer
  第63回日本生物工学会大会
- Place of Presentation
  東京農工大学小金井キャンパス
- Year and Date
  2011-09-27
- Data Source
  KAKENHI-PROJECT-22656190
[Presentation] メチル化CpG結合タンパク質を用いた新規メチル化頻度評価法の開発2010
- Author(s)
  平岡大介,村上慶行,吉田亘,秦健一郎,池袋一典
- Organizer
  第62回日本生物工学会大会
- Place of Presentation
  宮崎シーガイアワールドコンベンションセンターサミット
- Year and Date
  2010-10-29
- Data Source
  KAKENHI-PROJECT-22656190
[Presentation] 胎児・胎盤分化発育異常のエピジェネティクス-網羅的ゲノム・エピゲノム解析の試み-2009
- Author(s)
  秦健一郎
- Organizer
  日本周産期新生児学会
- Place of Presentation
  横浜
- Year and Date
  2009-07-12
- Data Source
  KAKENHI-PLANNED-20062010
[Presentation] Roles of genomic imprinting in reproduction2009
- Author(s)
  秦健一郎
- Organizer
  The 7th Conference of the Pacific Rim Society for Fertility and Sterility
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2009-08-12
- Data Source
  KAKENHI-PLANNED-20062010
[Presentation] 異常妊娠のエピジェネティクス2008
- Author(s)
  秦健一郎
- Organizer
  日本人類遺伝学会第53回大会
- Place of Presentation
  横浜
- Year and Date
  2008-09-28
- Data Source
  KAKENHI-PROJECT-19040031
[Presentation] 生殖機構のエピジェネティクス2008
- Author(s)
  秦健一郎
- Organizer
  大阪大学蛋白質研究所セミナー
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19040031
[Presentation] PLACENTAL DEFECTS IN MICEIACKENG MATERNAL METHYLATION IMPRINTS2007
- Author(s)
  秦健一郎
- Organizer
  第14回国際絨毛性疾患学会
- Place of Presentation
  福岡
- Year and Date
  2007-11-12
- Data Source
  KAKENHI-PROJECT-18590316
[Presentation] 流産のエピゲノム解析2007
- Author(s)
  秦健一郎
- Organizer
  第52回目本人類遺伝学会
- Place of Presentation
  福岡
- Year and Date
  2007-09-15
- Data Source
  KAKENHI-PROJECT-19040031
[Presentation] 流産のエピゲノム解析2007
- Author(s)
  秦健一郎
- Organizer
  第52回日本人類遺伝学会
- Place of Presentation
  福岡
- Year and Date
  2007-09-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590316
[Presentation] PLACENTAL DEFECTS IN MICELACKING MATERNAL METHYLATI ON IMIPRINTS2007
- Author(s)
  秦健一郎
- Organizer
  第14回国際絨毛性疾患学会
- Place of Presentation
  福岡
- Year and Date
  2007-11-12
- Data Source
  KAKENHI-PROJECT-19040031
[Presentation] PLACENTAL DEFECTS INMICELACKING MATERNAL METHYLATION IMPRINTS2007
- Author(s)
  K.HATA
- Organizer
  The 14th World Congress on Gestational Trophoblastic Disease
- Place of Presentation
  Fukuoka
- Year and Date
  2007-11-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590316
[Presentation] 流産のエピゲノム解析2007
- Author(s)
  秦健一郎, ほか
- Organizer
  第52回人類遺伝学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-15080208
[Presentation] Epigenetic analysis of abortions2007
- Author(s)
  K. Hata
- Organizer
  The 52th Japan Society of Human Geneticsk
- Place of Presentation
  Yokohama
- Year and Date
  2007-09-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590316
[Presentation] PLACENTAL DEFECTS IN MICELACKING MATERNAL METHYLATION IMPRINTS2007
- Author(s)
  秦健一郎
- Organizer
  第14回国際絨毛性疾患学会
- Place of Presentation
  福岡
- Year and Date
  2007-11-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590316
[Presentation] 日本人妊娠糖尿病の分子遺伝学的病態解析
- Author(s)
  春日義生、秦健一郎、宮越敬、福武麻里絵、正木繭、池ノ上学、落合大吾、松本直、峰岸一宏、前原佳代子、田中守、青木大輔
- Organizer
  第67回日本産科婦人科学会学術講演会
- Place of Presentation
  横浜
- Year and Date
  2015-04-09 – 2015-04-12
- Data Source
  KAKENHI-PROJECT-26462500
[Presentation] Common polymorphisms associated with gestational diabetes mellitus in Japanese women
- Author(s)
  Y. Kasuga, K. Miyakoshi, Y. Saisho, M. Fukutake, M. Masaki, S. Ikenoue, D. Ochiai, T. Matsumoto, K. Minegishi, K. Maehara, K. Hata, and M. Tanaka
- Organizer
  International DIP Symposium on Diabetes, Hypertension, Metabolic Syndrome & Pregnancy
- Place of Presentation
  Berlin, Germany
- Year and Date
  2015-05-15 – 2015-05-19
- Data Source
  KAKENHI-PROJECT-26462500

1. FUKUDA Atsuo (50254272)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
2. Nakabayashi Kazuhiko (10415557)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
3. SASAKI Hiroyuki (30183825)

# of Collaborated Projects: 3 results

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57. 冨川順子

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HATA Kenichiro 秦 健一郎

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エピゲノム変異不均一性を指標にした初期胚・胎児期環境のエピゲノムへの影響評価Principal Investigator

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少数細胞エピゲノミクス技術を利用した子宮内膜症の網羅的エピゲノム解析Principal Investigator

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ヒト胎芽期・胎児期・新生児期の環境因子によるエピゲノム変異とその経時的変化の同定Principal Investigator

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Screening for unknown factors of reproductive and developmental abnormalities from the viewpoint of epigenetic and/or genetic fragility.Principal Investigator

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Verification of possible iatrogenic epimutations by artificial reproductive technologies.Principal Investigator

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Epitranscriptome in placentas of AGA and SGA babiesPrincipal Investigator

HATA Kenichiro 秦健一郎