HAYASHI Hiroaki 林宏明

Researcher Number	60388965
Other IDs
Affiliation (based on the past Project Information) *help	2019 – 2022: 川崎医科大学, 医学部, 講師 2014: 川崎医科大学, 医学部, 講師 2012 – 2013: 川崎医科大学, 医学部, 助教
Review Section/Research Field	Except Principal Investigator Basic Section 53050:Dermatology-related / Hygiene
Keywords	Except Principal Investigator 動物モデル / 単純疱疹 / zosteriform / ケラチン / HSV / 脊髄後根神経節 / 重層扁平上皮 / C57BL/6Jマウス / エクリン汗腺 / デスモグレイン3 … More / 小水疱 / マウス / 単純ヘルペスウイルス / ケラチノサイト / デスモグレイン / デスモソーム / 単純疱疹ウイルス / 自己免疫疾患 / 癌疾患 / 免疫機能 / 珪肺症 / 遊離ケイ酸 / 珪酸 / 免疫 / 強皮症 / 珪肺 / 石綿 / NK細胞 / T細胞 / 全身性強皮症 / 自己免疫 / 悪性中皮腫 / シリカ / アスベスト Less

Analyses of the role of desmoglein during vesicle formation in herpes simplex using a three-dimensional and animal model
- Principal Investigator
  
  Yamamoto Takenobu
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Kawasaki Medical School
Comprehensive analysis for immunological characteristics of tumor and autoimmune diseases related with mineral particles and fibers
- Principal Investigator
  
  NISHIMURA Yasumitsu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kawasaki Medical School

All 2014 2013 2012 Other

All Journal Article Presentation Book

[Book] Chapter９ Immunostimulation by silica particles and the development of autoimmune dysregulation in "Immune Response Activation"2014
- Author(s)
  Lee S, Maeda M, Hayashi H, Matsuzaki H, Kumagai-Takei N, Nishimura Y, Otsuki T
- Total Pages
  274
- Publisher
  InTech publisher
- Data Source
  KAKENHI-PROJECT-24590770
[Book] Encyclopedia of Metalloproteins2013
- Author(s)
  Takei-Kumagai N, Lee S, Matsuzaki H, Hayashi H, Maeda M, Nishimura Y, Otsuki T
- Publisher
  Springer Science+Business Media
- Data Source
  KAKENHI-PROJECT-24590770
[Journal Article] Chronic exposure to asbestos enhances TGF-β1 production in the human adult T cell leukemia virus-immortalized T cell line MT-2.2014
- Author(s)
  Maeda M, Chen Y, Hayashi H, Kumagai-Takei N, Matsuzaki H, Lee S, Nishimura Y, Otsuki T.
- Journal Title
  
  Int J Oncol.
  
  Volume: 45 Issue: 6 Pages: 2522-2532
- DOI
  10.3892/ijo.2014.2682
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24580494, KAKENHI-PROJECT-24590770, KAKENHI-PROJECT-25460825, KAKENHI-PROJECT-25860471
[Journal Article] Functional properties of CD8+ lymphocytes in patients with pleural plaque and malignant mesothelioma2014
- Author(s)
  Kumagai-Takei N, Nishimura Y, Maeda M, Hayashi H, Matsuzaki H, Lee S, Kishimoto T, Fukuoka K, Nakano T, and Otsuki T
- Journal Title
  
  J Immunol Res
  
  Volume: 2014 Pages: 10-20
- DOI
  10.1155/2014/670140
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590770, KAKENHI-PROJECT-25460825, KAKENHI-PROJECT-25860470, KAKENHI-PROJECT-25860471
[Journal Article] Silica exposure and altered regulation of autoimmunity2014
- Author(s)
  Lee S, Matsuzaki H, Kumagai-Takei N, Yoshitome K, Maeda M, Chen Y, Kusaka M, Urakami K, Hayashi H, Fujimoto W, Nishimura Y, Otsuki T,
- Journal Title
  
  Environ Health Prev Med
  
  Volume: 19 Issue: 5 Pages: 322-9
- DOI
  10.1007/s12199-014-0403-9
- NAID
  50009312838
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590770, KAKENHI-PROJECT-25460825, KAKENHI-PROJECT-25860471
[Journal Article] 珪酸曝露による免疫影響2014
- Author(s)
  松崎秀紀, 前田恵, 林宏明, 武井直子, 李順姫, 吉留敬, 草加勝康, 浦上更三, 西村泰光, 兵藤文則, 大槻剛巳
- Journal Title
  
  日本予防医学会雑誌
  
  Volume: 9 Pages: 1-8
- NAID
  40020166317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590770
[Journal Article] Effect of asbestos exposure on differentiation of cytotoxic T lymphocytes in MLR of human PBMCs2013
- Author(s)
  Kumagai-takei N, Nishimura Y, Maeda M, Hayashi H, Matsuzaki H, Lee S, Hiratsuka J, Otsuki T
- Journal Title
  
  Am J Respir Cell Mol Biol
  
  Volume: 49(1) Issue: 1 Pages: 28-36
- DOI
  10.1165/rcmb.2012-0134oc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590770, KAKENHI-PROJECT-25293267, KAKENHI-PROJECT-25460825, KAKENHI-PROJECT-25860471
[Journal Article] Alteration of cytoskeletal molecules in a human T cell line caused by continuous exposure to chrysotile asbestos.2013
- Author(s)
  Maeda, M., Chen, Y., Kumagai-Takei, N., Hayashi, H., Matsuzaki, H., Lee, S., Hiratsuka, JI., Nishimura, Y., Kimura, Y., Otsuki T.
- Journal Title
  
  Immunobiology
  
  Volume: (in press) Issue: 9 Pages: 1184-91
- DOI
  10.1016/j.imbio.2013.04.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890237, KAKENHI-PROJECT-24590770, KAKENHI-PROJECT-25293267, KAKENHI-PROJECT-25460825, KAKENHI-PROJECT-25860471
[Journal Article] Exploration of biomarkers for asbestos exposure and occurrence of malignant mesothelioma based on the immunological effects of asbestos2013
- Author(s)
  Matsuzaki H, Lee S, Kumagai-Takei N, Hayashi H, Miura Y, Chen Y, Maeda M, Yamamoto S, Hatayama T, Nishimura Y, Otsuki T
- Journal Title
  
  J Postgenomics: Drug & Biomarker Dev
  
  Volume: S2 Issue: 02 Pages: 1-6
- DOI
  10.4172/2153-0602.s2-001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590770, KAKENHI-PROJECT-25460825
[Journal Article] Environmental factors producing autoimmune dysregulation-Chronic activation of T cells caused by silica exposure2012
- Author(s)
  Suni Lee
- Journal Title
  
  Immunobiology
  
  Volume: (Epub ahead of print) Issue: 7 Pages: 43-48
- DOI
  10.1016/j.imbio.2011.12.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790550, KAKENHI-PROJECT-23890237, KAKENHI-PROJECT-24590770
[Journal Article] Resistance to asbestos-induced apoptosis with continuous exposure to crocidolite ona human T cell.2012
- Author(s)
  Maeda, M., Yamamoto, S., Chen, Y.,Kumagai-Takei, N., Hayashi, H., Matsuzaki, H., Lee, S., Hatayama, T., Miyahara, N., Katoh, M., Hiratsuka, J., Nishimura, Y., Otsuki, T.
- Journal Title
  
  Sci. Total Environ.
  
  Volume: 429 Pages: 174-182
- DOI
  10.1016/j.scitotenv.2012.04.043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890237, KAKENHI-PROJECT-24590770
[Journal Article] Asbestos-induced cellular and molecular alteration of immunocompetent cells and the relationship with chronic inflammation and carcinogenesis2012
- Author(s)
  Matsuzaki Hidenori
- Journal Title
  
  Journal of Biomedicine and Biotechnology
  
  Volume: 2012 Pages: 1-9
- DOI
  10.1155/2012/492608
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700933, KAKENHI-PROJECT-22790550, KAKENHI-PROJECT-23890237, KAKENHI-PROJECT-24590770
[Presentation] 悪性中皮腫および全身性強皮症患者における免疫関連遺伝子発現動態の解析2013
- Author(s)
  西村泰光，李順姫，武井直子，松﨑秀紀，林宏明，藤本亘，守田吉孝，岸本卓巳，大槻剛巳
- Organizer
  第83回日本衛生学会
- Place of Presentation
  金沢大学（金沢）
- Data Source
  KAKENHI-PROJECT-24590770
[Presentation] 珪肺症と強皮症における免疫機能亢進の類似およびTh細胞機能の差違
- Author(s)
  西村泰光，李順姫, 武井直子, 松﨑秀紀, 藤本亘, 林宏明 , 守田吉孝 , 大槻剛巳
- Organizer
  第13回分子予防環境医学研究会
- Place of Presentation
  和歌山県民文化会館 (和歌山)
- Data Source
  KAKENHI-PROJECT-24590770
[Presentation] The characteristics of activated lymphocytes in silicosis differing in Th17 phenotype from systemic sclerosis
- Author(s)
  Nishimura Y, Lee S, Kumagai-Takei N, Matsuzaki H, Hayashi H, Fujimoto W, Morita Y, Kusaka M, Otsuki T
- Organizer
  The 53rd annual Meeting. Society of Toxicology
- Place of Presentation
  Poenix Convention Center (Phoenix, Arizona)
- Data Source
  KAKENHI-PROJECT-24590770
[Presentation] 多面的免疫機能解析による珪肺と全身性強皮症の比較
- Author(s)
  西村泰光，李順姫，武井直子，松崎秀紀，林宏明，藤本亘，守田吉孝，草加勝康，大槻剛巳
- Organizer
  第87回日本産業衛生学会
- Place of Presentation
  岡山（岡山コンベンションセンター）
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-24590770

1. NISHIMURA Yasumitsu (90360271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
2. OTSUKI Takemi (40160551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
3. TAKEI Naoko (00509276)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MATSUZAKI Hidenori (80335463)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
5. LEE Suni (70414026)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
6. FUJIMOTO Wataru (50165429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
7. Yamamoto Takenobu (50379799)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 前田恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 熊谷直子

# of Collaborated Projects: 0 results

# of Collaborated Products: 11 results

HAYASHI Hiroaki 林 宏明

Research Projects

Research Products

Co-Researchers

Analyses of the role of desmoglein during vesicle formation in herpes simplex using a three-dimensional and animal model

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive analysis for immunological characteristics of tumor and autoimmune diseases related with mineral particles and fibers

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Chapter９ Immunostimulation by silica particles and the development of autoimmune dysregulation in "Immune Response Activation"2014

Author(s)

Total Pages

Publisher

Data Source

[Book] Encyclopedia of Metalloproteins2013

Author(s)

Publisher

Data Source

[Journal Article] Chronic exposure to asbestos enhances TGF-β1 production in the human adult T cell leukemia virus-immortalized T cell line MT-2.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Functional properties of CD8+ lymphocytes in patients with pleural plaque and malignant mesothelioma2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Silica exposure and altered regulation of autoimmunity2014

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] 珪酸曝露による免疫影響2014

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Effect of asbestos exposure on differentiation of cytotoxic T lymphocytes in MLR of human PBMCs2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Alteration of cytoskeletal molecules in a human T cell line caused by continuous exposure to chrysotile asbestos.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Exploration of biomarkers for asbestos exposure and occurrence of malignant mesothelioma based on the immunological effects of asbestos2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Environmental factors producing autoimmune dysregulation-Chronic activation of T cells caused by silica exposure2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Resistance to asbestos-induced apoptosis with continuous exposure to crocidolite ona human T cell.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Asbestos-induced cellular and molecular alteration of immunocompetent cells and the relationship with chronic inflammation and carcinogenesis2012

Author(s)

Journal Title

DOI

Data Source

[Presentation] 悪性中皮腫および全身性強皮症患者における免疫関連遺伝子発現動態の解析2013

Author(s)

Organizer

Place of Presentation

HAYASHI Hiroaki 林宏明