Oono Takae 大野孝恵

… Alternative Names

Ohno Takae 大野孝恵

OHNO Takae 大野孝恵

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Researcher Number	60508109
Other IDs
Affiliation (Current)	2025: 帝京大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2018 – 2023: 帝京大学, 医学部, 准教授 2008 – 2012: Teikyo University, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 46030:Function of nervous system-related / Neurophysiology and muscle physiology / Neurophysiology and muscle physiology Except Principal Investigator Basic Section 46010:Neuroscience-general-related
Keywords	Principal Investigator 可塑性 / 脊髄 / ホールセル記録 / 光遺伝学的刺激法 / GluN2B / シナプス除去 / 皮質脊髄路 / optical imaging / exo utero electroporation / heterotypic co-culture … More / corticospinal synapse / 運動学習 / 細胞間ネットワーク / 小細胞系 / 赤核 / 選択的細胞除去法 / イムノトキシン / 脊髄投射 / 下オリーブ核投射 / 光遺伝学的刺激 / 視床後核 / 下オリーブ核 / 赤核回路網 / 長期増強LTP / 急性スライス / 脊髄運動ニューロン / 長期増強(LTP) / シナプス可塑性 / 皮質運動ニューロン直接接合 / 皮質運動ニューロン直接結合 / 運動ニューロン / live imaging / competition / synapse elimination / カルシウム流入量 / Glun2A / シナプス / 臨界期 / CaMKII / GluN2A / GluRε1(NR2A) / GluRε2(NR2B) / whole cell recording / GluN2A(GluR ε 1 / GluN2B(GluR ε 2 / NR2A) / GluN2A (GluRε1 / NR2B) / GluN2B (GluRε2 / knockout mice … More Except Principal Investigator 樹状突起 / 急性スライス / partition 細胞 / 運動系 / パッチクランプ / オプトジェネティクス / 皮質脊髄路 / 運動神経細胞 Less

運動神経細胞のシナプス特性解析：生後発達過程で確立される入力／されない入力
- Principal Investigator
  
  福田諭
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Teikyo University
赤核大細胞・小細胞における上肢運動情報のクロスオーバーPrincipal Investigator
- Principal Investigator
  
  大野孝恵
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46030:Function of nervous system-related
- Research Institution
  Teikyo University
Developmental change in synaptic plasticity of corticomotoneuronal direct connections: Do motoneurons learn?Principal Investigator
- Principal Investigator
  
  Ohno Takae
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46030:Function of nervous system-related
- Research Institution
  Teikyo University
Synapse elimination and its molecular mechanisms of in vitro slice culturePrincipal Investigator
- Principal Investigator
  
  OHNO Takae
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Teikyo University
Activity-dependent elimination of corticospinal synapses and NMDA receptor subtypePrincipal Investigator
- Principal Investigator
  
  OHNO Takae
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Teikyo University

All 2023 2022 2021 2020 2019 2018 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Book Other

[Book] 皮質脊髄路シナプス除去の分子メカニズムブレインサイエンスレビュー20132013
- Author(s)
  大野孝恵
- Publisher
  クバプロ出版
- Data Source
  KAKENHI-PROJECT-22500359
[Book] ブレインサイエンスレビュー20132013
- Author(s)
  大野孝恵
- Publisher
  クバプロ
- Data Source
  KAKENHI-PROJECT-22500359
[Journal Article] 発達期マウスにおける一過性皮質脊髄運動ニューロン直接結合：その除去メカニズムと個体・系統発生的意義2021
- Author(s)
  大野孝恵
- Journal Title
  
  女醫界
  
  Volume: 824 Pages: 79-83
- Data Source
  KAKENHI-PROJECT-18K06528
[Journal Article] 発達期マウスにおける一過性皮質脊髄運動ニューロン直接結合: その除去メカニズムと個体・系統発生的意義2021
- Author(s)
  大野孝恵
- Journal Title
  
  女医界
  
  Volume: 824 Pages: 79-83
- Data Source
  KAKENHI-PROJECT-18K06528
[Journal Article] 幼若期齧歯類において形成される皮質脊髄軸索-上肢運動ニューロン間直接シナプスは高等霊長類に類似した分布を示す2018
- Author(s)
  新戸瑞穂、福田諭、大野孝恵、桜井正樹
- Journal Title
  
  帝京医学雑誌
  
  Volume: 41 Pages: 137-148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06528
[Journal Article] Specific involvement of GluRε2 (NR2B)-containing NMDA receptors in the developmental elimination of corticospinal synapses2010
- Author(s)
  Takae Ohno, Hitoshi Maeda, Naoyuki Murabe, Tsutomu Kamiyama, Noboru Yoshioka, Masayoshi Mishina, and Masaki Sakurai
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 107 Pages: 15252-15257
- Data Source
  KAKENHI-PROJECT-22500359
[Journal Article] Masayoshi Mishina and Masaki Sakurai. Specific involvement of GluRε2 (NR2B)-containing NMDA receptors in the developmental elimination of corticospinal synapses.2010
- Author(s)
  Takae Ohno, Hitoshi Maeda, Naoyuki Murabe, Tsutomu Kamiyama, Noboru Yoshioka, Masayoshi Mishina, Masaki Sakurai.
- Journal Title
  
  Proc Natl Acad Sci USA (in press)
- Data Source
  KAKENHI-PROJECT-20800047
[Journal Article] Specific involvement of postsynaptic GluN2B-containing NMDA receptors in the developmental elimination of corticospinal synapses2010
- Author(s)
  T Ohno, H Maeda, N Murabe, T Kamiyama, N Yoshioka, M Mishina, M Sakurai
- Journal Title
  
  PNAS
  
  Volume: 107 Pages: 15252-15257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500359
[Presentation] The red nucleus and its circuit network: cell identification through a target-selective approach utilizing retrograde vectors2023
- Author(s)
  Takae Ohno
- Organizer
  Neuroscinece 2023, Washington, D.C., Nov. 11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06475
[Presentation] New approach of cell types and their networks of red nucleus2023
- Author(s)
  Takae Ohno
- Organizer
  The 100th Annual Meeting of the Physiological Society of Japan
- Data Source
  KAKENHI-PROJECT-18K06528
[Presentation] New approach of cell types and their networks of red nucleus2023
- Author(s)
  Takae Ohno
- Organizer
  The 100th Annual Meeting of the Physiological Society of Japan
- Data Source
  KAKENHI-PROJECT-22K06475
[Presentation] The red nucleus and its networks: a selective approach to the target cells using retrograde vectors2023
- Author(s)
  Takae Ohno
- Organizer
  The 46th Annual Meeting of the Japan Neuroscience Society, Sendai, Japan, Aug 2, 2023
- Data Source
  KAKENHI-PROJECT-22K06475
[Presentation] 赤核とその回路網：逆行性ベクターによる細胞選択的アプローチ2023
- Author(s)
  大野孝恵
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-22K06475
[Presentation] The elimination of cortico-motoneuronal synapses during development: involvement of GluN2B containing NMDA receptor2022
- Author(s)
  Takae Ohno
- Organizer
  The 99th Annual Meeting of the Physiological Society of Japan
- Data Source
  KAKENHI-PROJECT-18K06528
[Presentation] The elimination of cortico-motoneuronal synapses during development: involvement of GluN2B containing NMDA receptior2022
- Author(s)
  大野孝恵
- Organizer
  第99回日本生理学会
- Data Source
  KAKENHI-PROJECT-18K06528
[Presentation] Developmental synapse elimination in cortico-motoneuronal synapse2021
- Author(s)
  大野孝恵
- Organizer
  第44回日本神経科学学会
- Data Source
  KAKENHI-PROJECT-18K06528
[Presentation] Involvement of GluN2B-containing NMDA receptors in the elimination of cortico-motoneuronal synapses during development2021
- Author(s)
  Takae Ohno
- Organizer
  Society for Neuroscience, Chicago, 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06528
[Presentation] Regression and its time course of transient cortico-motoneuronal direct connections during development in mice2020
- Author(s)
  大野孝恵
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-18K06528
[Presentation] Temporal profile of transient corticomotoneuronal direct connection in the rodent2019
- Author(s)
  Takae Ohno, Satoshi Fukuda, Naoyuki Murabe, Hiroaki Mizukami, Keiya Ozawa, Toshihiro Hayashi, Masaki Sakurai
- Organizer
  北米神経科学学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06528
[Presentation] Temporal profile of developmental change in corticomotoneuronal direct connection in rodents2018
- Author(s)
  Takae Ohno, Satoshi Fukuda, Naoyuki Murabe, Hiroaki Mizukami, Keiya Ozawa, Toshihiro Hayashi, Masaki Sakurai
- Organizer
  The 41st Annual Meeting of the Japan Neuroscience Society
- Data Source
  KAKENHI-PROJECT-18K06528
[Presentation] Decline of GluN2B is crucially important for closing the critical period in corticospinal plasticity2012
- Author(s)
  M.Isowaki, T.Ohno, N.Isoo, N.Murabe,H.Maeda, S.Fukuda, N.Yoshioka, M.Mishina, M.Sakurai
- Organizer
  Society for Neuroscience 2012
- Place of Presentation
  New Oleans Convention Center
- Year and Date
  2012-10-14
- Data Source
  KAKENHI-PROJECT-22500359
[Presentation] 臨界期は操作出来るのか?2012
- Author(s)
  大野孝恵、礒脇睦美、磯尾紀子、村部直之、前田仁士、福田諭、三品昌美、桜井正樹
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2012-09-18
- Data Source
  KAKENHI-PROJECT-22500359
[Presentation] 幼弱期神経回路が有する柔軟性は取り戻すことができるか？in vitro錐体路系での研究2012
- Author(s)
  大野孝恵
- Organizer
  第53回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-22500359
[Presentation] 臨界期は操作出来るのか？2012
- Author(s)
  大野孝恵
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-22500359
[Presentation] NMDA受容体サブユニットは皮質脊髄路シナプス除去の臨界期終了に必須の役割を果たしている2011
- Author(s)
  大野孝恵、礒脇睦美、磯尾紀子、村部直之、前田仁士、福田諭、吉岡昇、三品昌美、桜井正樹
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-22500359
[Presentation] Developmental decline of 2B subunit containing NMDA receptor is essential for closing the critical period plasticity window in mouse corticospinal synapse elimination2011
- Author(s)
  I.Ohno, N.Isoo, N.Murabe, H.Maeda, S.Fukuda, N.Yoshioka, M.Mishina, M.Sakurai
- Organizer
  NEUROSCIENSE 2011
- Place of Presentation
  Washington DC
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-22500359
[Presentation] Developmental decline of 2B subunit containing NMDA receptor is essential for closing the critical period plasticity window in mouse corticospinal synapse elimination2011
- Author(s)
  T.Ohno, N.Isoo, N.Murabe, H.Maeda, S.Fukuda, N.Yoshioka, M.Mishina, M.Sakurai
- Organizer
  Society for Neuroscience 2011
- Place of Presentation
  Washington DC Convention Center
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-22500359
[Presentation] 発達期皮質脊髄路シナプス除去に対するGluN2B及び2Aノックアウトの影響:Ca2+流入量の違いか下流のシグナル伝達メカニズムの違いか?2010
- Author(s)
  大野孝恵、前田仁士、村部直之、上山勉、吉岡昇、三品昌美、桜井正樹
- Organizer
  第33回日本神経科学大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-22500359
[Presentation] 発達期皮質脊髄路シナプス除去に対するGluN2B及び2Aノックアウトの影響: Ca2+流入量の違いか下流のシグナル伝達メカニズムの違いか?2010
- Author(s)
  大野孝恵、前田仁士、村部直之、上山勉、吉岡昇、三品昌美、桜井正樹
- Organizer
  第33回日本神経科学大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-22500359
[Presentation] Differential effect of GluN2B KO vs.GluN2A KO in corticospinal synapse elimination during development2010
- Author(s)
  T Ohno, H Maeda, N Murabe, T Kamiyama, N Yoshioka, M Mishina, M Sakurai
- Organizer
  Society for Neuroscience 2010
- Place of Presentation
  San Diego Convention Center
- Year and Date
  2010-11-14
- Data Source
  KAKENHI-PROJECT-22500359
[Presentation] Differential effect of GluN2B KO vs. GluN2A KO in corticospinal synapse elimination during development2010
- Author(s)
  T Ohno, H Maeda, N Murabe, T Kamiyama,N Yoshioka, M Mishina, M Sakurai
- Organizer
  Society for Neuroscience 2010
- Place of Presentation
  San Diego Convention Center
- Year and Date
  2010-11-14
- Data Source
  KAKENHI-PROJECT-22500359
[Presentation] GluR ε 2 (NR2B)-containing NMDA receptors are specifically involved in the corticospinal synapse elimination during development2009
- Author(s)
  T Ohno, H Maeda, N Murabe, T Kamiyama, N Yoshioka, M Mishina, M Sakurai
- Organizer
  Society for Neuroscience 2009
- Place of Presentation
  Chicago Convention Center
- Year and Date
  2009-10-20
- Data Source
  KAKENHI-PROJECT-20800047
[Presentation] 第32回日本神経科学大会:皮質脊髄路シナプス除去に対するGluRε2 (NR2B)の選択的関与2009
- Author(s)
  大野孝恵、前田仁士、村部直之、上山勉、吉岡昇、三品昌美、桜井正樹
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-20800047
[Presentation] Society for Neuroscience 2009: GluRε2 (NR2B)-containing NMDA receptors are specifically involved in the corticospinal synapse elimination during development2009
- Author(s)
  T Ohno, H Maeda, N Murabe, T Kamiyama, N Yoshioka, M Mishina
- Organizer
  Chicago Convention Center
- Year and Date
  2009-10-20
- Data Source
  KAKENHI-PROJECT-20800047
[Presentation] 皮質脊髄路シナプス除去に対するGluRε2 (NR2B)の選択的関与2009
- Author(s)
  大野孝恵、前田仁士、村部直之、上山勉、吉岡昇、三品昌美、桜井正樹
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-20800047
[Presentation] マウス皮質脊髄シナプスのGluRε2(2B)依存的発達2008
- Author(s)
  大野孝恵, 前田仁士, 吉岡昇, 三品昌美, 桜井正樹
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  パシフイコ横浜
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-20800047
[Presentation] 第49回日本神経学会総会:マウス皮質脊髄シナプスのGluRε2(2B)依存的発達2008
- Author(s)
  大野孝恵、前田仁士、吉岡昇、三品昌美、桜井正樹
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-20800047
[]

1. 福田諭 (50425641)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
2. 林俊宏 (60505890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Oono Takae 大野 孝恵

Ohno Takae 大野 孝恵

OHNO Takae 大野 孝恵

Research Projects

Research Products

Co-Researchers

運動神経細胞のシナプス特性解析：生後発達過程で確立される入力／されない入力

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

赤核大細胞・小細胞における上肢運動情報のクロスオーバーPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Developmental change in synaptic plasticity of corticomotoneuronal direct connections: Do motoneurons learn?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Synapse elimination and its molecular mechanisms of in vitro slice culturePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Activity-dependent elimination of corticospinal synapses and NMDA receptor subtypePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 皮質脊髄路シナプス除去の分子メカニズムブレインサイエンスレビュー20132013

Author(s)

Publisher

Data Source

[Book] ブレインサイエンスレビュー20132013

Author(s)

Publisher

Data Source

[Journal Article] 発達期マウスにおける一過性皮質脊髄運動ニューロン直接結合：その除去メカニズムと個体・系統発生的意義2021

Author(s)

Journal Title

Data Source

[Journal Article] 発達期マウスにおける一過性皮質脊髄運動ニューロン直接結合: その除去メカニズムと個体・系統発生的意義2021

Author(s)

Journal Title

Data Source

[Journal Article] 幼若期齧歯類において形成される皮質脊髄軸索-上肢運動ニューロン間直接シナプスは高等霊長類に類似した分布を示す2018

Author(s)

Journal Title

Data Source

[Journal Article] Specific involvement of GluRε2 (NR2B)-containing NMDA receptors in the developmental elimination of corticospinal synapses2010

Author(s)

Journal Title

Data Source

[Journal Article] Masayoshi Mishina and Masaki Sakurai. Specific involvement of GluRε2 (NR2B)-containing NMDA receptors in the developmental elimination of corticospinal synapses.2010

Author(s)

Journal Title

Data Source

[Journal Article] Specific involvement of postsynaptic GluN2B-containing NMDA receptors in the developmental elimination of corticospinal synapses2010

Author(s)

Journal Title

Data Source

[Presentation] The red nucleus and its circuit network: cell identification through a target-selective approach utilizing retrograde vectors2023

Author(s)

Organizer

Data Source

[Presentation] New approach of cell types and their networks of red nucleus2023

Author(s)

Organizer

Data Source

[Presentation] New approach of cell types and their networks of red nucleus2023

Author(s)

Organizer

Data Source

Oono Takae 大野孝恵

Ohno Takae 大野孝恵

OHNO Takae 大野孝恵