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HOSOMI SHUHEI  細見 周平

… Alternative Names

Hosomi Shuhei  細見 周平

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Researcher Number 60554938
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-8808-5672
Affiliation (Current) 2025: 大阪公立大学, 大学院医学研究科, 准教授
Affiliation (based on the past Project Information) *help 2024: 大阪公立大学, 大学院医学研究科, 准教授
2022 – 2023: 大阪公立大学, 大学院医学研究科, 講師
2016 – 2021: 大阪市立大学, 大学院医学研究科, 講師
2015: 大阪市立大学, 大学院医学研究科, 病院講師
2014: 大阪市立大学, 医学(系)研究科(研究院), 病院講師
Review Section/Research Field
Principal Investigator
Basic Section 53010:Gastroenterology-related / Immunology
Except Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / Medium-sized Section 57:Oral science and related fields / Basic Section 57070:Developmental dentistry-related / Basic Section 55020:Digestive surgery-related / Basic Section 53010:Gastroenterology-related / Basic Section 57060:Surgical dentistry-related
Keywords
Principal Investigator
小胞体ストレス / クローン病 / 肥満細胞 / NKG2D / 炎症性腸疾患 / 便秘モデル / オプシン / 光受容 / 腸蠕動音 / 消化管蠕動 … More / interleukin-23 / interleukin-12 / Amphiregulin / 樹状細胞 / 腸管上皮細胞間リンパ球 / 自然免疫 / MULT1 / IgA / Xbp1 / 腸管免疫 … More
Except Principal Investigator
味覚受容体 / 味覚障害 / Tas1r3 / 骨格筋 / TAS1R3受容体 / 5-FU系抗がん剤 / 小腸上皮特異的Tas1r3欠損マウス / ヘテロダイマー / Gタンパク質共益型受容体 / 骨粗しょう症 / サルコペニア / エネルギー代謝 / うま味受容体 / 間葉系幹細胞 / 脂肪細胞分化 / 小児肥満 / 脂肪 / 肥満症 / 肥満 / 肝再生 / 小腸上皮味覚受容体 / 小腸 / NAFLD / 炎症性腸疾患 / 炎症発癌 / 栄養吸収 / 腸炎モデル / 薬剤性腸炎モデル / 脂肪肝炎モデル / がん筋層浸潤 / 炎症 / 骨 / DKK-1 / 扁平上皮がん / シングルセルRNA-seq / 舌筋再生 / 筋再生 / リンパ節転移 / 口腔扁平上皮がん / 舌がん / 舌筋 Less
  • Research Projects

    (10 results)
  • Research Products

    (9 results)
  • Co-Researchers

    (24 People)
  •  音と光による消化管蠕動制御デバイス開発に向けた基盤研究Principal Investigator

    • Principal Investigator
      細見 周平
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Osaka Metropolitan University
  •  5-FU系抗がん剤による味覚障害に対する消化管味覚受容体を介した新たな治療戦略

    • Principal Investigator
      平良 高一
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Osaka Metropolitan University
  •  うま味でサルコペニア克服に挑戦する

    • Principal Investigator
      古株 彰一郎
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 57:Oral science and related fields
    • Research Institution
      Kyushu Dental College
  •  Understanding of the relationship between skeletal muscle and cancer for regulating muscle invasion of oral squamous cell carcinoma

    • Principal Investigator
      Kokabu Shoichiro
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Kyushu Dental College
  •  Integrated understanding of taste receptor-mediated intestinal homeostasis mechanisms

    • Principal Investigator
      Fujiwara Yasuhiro
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Osaka Metropolitan University
      Osaka City University
  •  Elucidation of the mechanism of NAFLD and liver regeneration failure using mice deficient in small intestinal epithelial specific taste receptors.

    • Principal Investigator
      Shinkawa Hiroji
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Osaka Metropolitan University
      Osaka City University
  •  The molecular mechanism of umami receptor in energy metabolism for preventing pediatric obesity

    • Principal Investigator
      Morikawa Kazumasa
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57070:Developmental dentistry-related
    • Research Institution
      Iwate Medical University
  •  Analysis of the Mechanisms of Enterocolitis Development and Intestinal Fibrosis Mediated by Endoplasmic Reticulum Stress in Mast CellsPrincipal Investigator

    • Principal Investigator
      Hosomi Shuhei
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Osaka Metropolitan University
      Osaka City University
  •  Immune response for endoplasmic reticulum stress on intestinal inflammationPrincipal Investigator

    • Principal Investigator
      HOSOMI Shuhei
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Immunology
    • Research Institution
      Osaka City University
  •  Role of endoplasmic reticulum stress on induction of NKG2D-ligand, leading to enteritisPrincipal Investigator

    • Principal Investigator
      Hosomi Shuhei
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Immunology
    • Research Institution
      Osaka City University

All 2024 2023 2020 2019 2018 2017 2015

All Journal Article Presentation Book

  • [Book] 臨床免疫・アレルギー科2020

    • Author(s)
      細見周平
    • Total Pages
      6
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-PROJECT-19K08450
  • [Journal Article] Epithelial endoplasmic reticulum stress orchestrates a protective IgA response2019

    • Author(s)
      Grootjans J, Krupka N, Hosomi S, Matute JD, Hanley T, Saveljeva S, Gensollen T, Heijmans J, Li H, Limenitakis JP, Ganal-Vonarburg SC, Suo S, Luoma AM, Shimodaira Y, Duan J, Shih DQ, Conner ME, Glickman JN, Fuhler GM, Palm NW, de Zoete MR, van der Woude CJ, Yuan GC, Targan SR, Macpherson AJ, Kaser A, Blumberg RS
    • Journal Title

      Science

      Volume: 363 Issue: 6430 Pages: 993-998

    • DOI

      10.1126/science.aat7186

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19162
  • [Journal Article] New Insights Into the Regulation of Natural-Killer Group 2 Member D (NKG2D) and NKG2D-Ligands: Endoplasmic Reticulum Stress and CEA-Related Cell Adhesion Molecule 12018

    • Author(s)
      Hosomi Shuhei、Grootjans Joep、Huang Yu-Hwa、Kaser Arthur、Blumberg Richard S.
    • Journal Title

      Frontiers in Immunology

      Volume: 9 Pages: 1324-1324

    • DOI

      10.3389/fimmu.2018.01324

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K19162
  • [Journal Article] Intestinal epithelial cell endoplasmic reticulum stress promotes MULT1 up-regulation and NKG2D-mediated inflammation2017

    • Author(s)
      Hosomi Shuhei、Grootjans Joep、Tschurtschenthaler Markus、Krupka Niklas、Matute Juan D.、Flak Magdalena B.、Martinez-Naves Eduardo、Gomez del Moral Manuel、Glickman Jonathan N.、Ohira Mizuki、Lanier Lewis L.、Kaser Arthur、Blumberg Richard
    • Journal Title

      The Journal of Experimental Medicine

      Volume: 214 Issue: 10 Pages: 2985-2997

    • DOI

      10.1084/jem.20162041

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K19162
  • [Journal Article] 1.ER stress and autophagy as interlinking pathways in the pathogenesis of inflammatory bowel disease2015

    • Author(s)
      Hosomi S, Kaser A, Blumberg RS
    • Journal Title

      Current Opinion in Gastroenterology

      Volume: 31(1) Issue: 1 Pages: 81-88

    • DOI

      10.1097/mog.0000000000000144

    • Open Access
    • Data Source
      KAKENHI-PROJECT-26893231
  • [Presentation] 小腸上皮特異的味覚受容体の代謝異常関連脂肪性肝疾患における役割2024

    • Author(s)
      中西 紘一、新川 寛二、河野 沙紀、白井 大介、細見 周平、岩崎 有作、南山 幸子、竹村 茂一、石沢 武彰
    • Organizer
      第77回日本酸化ストレス学会
    • Data Source
      KAKENHI-PROJECT-21K08759
  • [Presentation] TNFα阻害剤投与中のクローン病手術症例の術後再発予防治療の検討2023

    • Author(s)
      細見周平、藤本晃士、小林由美恵、中田理恵子、西田裕、鎌田紀子、藤原靖弘
    • Organizer
      第78回日本大腸肛門病学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K08450
  • [Presentation] 小胞体ストレス応答による2017

    • Author(s)
      細見 周平、杉田 奈央子、大谷 恒史、 山上 博一、谷川 徹也、渡辺 俊雄、藤原 靖弘
    • Organizer
      日本消化器免疫学会総会
    • Data Source
      KAKENHI-PROJECT-16K19162
  • [Presentation] B Cells and Dendritic Cells React to Intestinal Epithelial Stress with a Coordinated and Protective IgA Response2015

    • Author(s)
      Joep Grootjans, Shuhei Hosomi, Magdalena B. Flak, Kathy D. McCoy, Andrew J. Macpherson, Arthur Kaser and Richard S. Blumberg
    • Organizer
      17th International Congress of Mucosal Immunology
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2015-07-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26893231
  • 1.  Kokabu Shoichiro (30448899)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  Fujiwara Yasuhiro (40285292)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  Shinkawa Hiroji (00554932)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  Morikawa Kazumasa (70514686)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  土生 学 (00360058)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  Addison William (40845046)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  佐藤 毅 (60406494)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  矢田 直美 (60468022)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  永野 健一 (60834348)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  中平 光彦 (10253353)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  竹村 茂一 (00322363)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  南山 幸子 (00362989)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 13.  田中 肖吾 (50382114)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  久保 正二 (80221224)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  橋口 大輔 (00625965)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  齊藤 桂子 (70788744)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  中道 敦子 (20567341)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  吉田 竜介 (60380705)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  寺北 明久 (30212062)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  小林 由美恵 (90911610)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  平良 高一 (00783713)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  Sugita Naoko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 23.  Blumberg Richard S.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 24.  Richard Blumberg S.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results

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