TAKAHASHI Yasuhito 高橋康仁

Researcher Number	60567668
Affiliation (Current)	2025: 東京医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2013 – 2024: 東京医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 90140:Medical technology assessment-related / Orthopaedic surgery Except Principal Investigator Basic Section 90110:Biomedical engineering-related / Basic Section 90140:Medical technology assessment-related / Basic Section 26040:Structural materials and functional materials-related / Biomedical engineering/Biomaterial science and engineering / Orthopaedic surgery
Keywords	Principal Investigator ラマン分光 / 細胞外マトリックス / デラミネーション耐性 / 微構造解析 / 脛骨インサート / 超高分子量ポリエチレン / 人工膝関節 / 低温劣化 / 構造健全性 / 残留応力 … More / 相変態 / 加速エージング / 複合セラミックス / 人工股関節 / 化学物理 / 分析科学 / 生体分子 / 生体材料 / I型コラーゲン / 膝靱帯 / 近赤外ラマン分光 / 組織変性 / 光バイオプシー / 組織診断 / 近赤外レーザー / 前十字靭帯 / 微細構造 / ヒト軟骨 … More Except Principal Investigator 人工股関節 / 人工股関節置換術 / 超高分子量ポリエチレン / 高度架橋ポリエチレン / 微細構造 / ポリエチレン / 血中金属濃度 / 摩耗 / 偽腫瘍 / 人工股関節摺動面 / 長期耐用性 / 耐疲労性 / 抗酸化性 / 耐摩耗性 / 衝撃疲労試験 / 寛骨臼ライナー / 生体環境劣化 / セラミック / インプラント / 低温劣化 / 構造健全性 / 複合セラミックス / エージング / 相転移 / ジルコニア強化型アルミナ / 残留応力 / 構造安定性 / 加速エージング / セラミック・インプラント / 人工関節 / 力学特性 / ビタミンＥ / クリープ / クリープ変形速度 / ポリエチレンライナー Less

人工股関節周囲組織反応(ALTR)の病態解明に関する基礎的および臨床的検討
- Principal Investigator
  
  石田常仁
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Tokyo Medical University
超長寿命型人工膝関節開発のためのデラミネーション破壊抑制に関する研究Principal Investigator
- Principal Investigator
  
  高橋康仁
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90140:Medical technology assessment-related
- Research Institution
  Tokyo Medical University
高度架橋ポリエチレン製人工股関節の超長期耐用性の実現を目指した材料設計の至適化
- Principal Investigator
  
  立岩俊之
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90140:Medical technology assessment-related
- Research Institution
  Tokyo Medical University
A novel proposal for validating the durability of ceramic-composite artificial hip joints and improving its prediction accuracyPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Yasuhito
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90140:Medical technology assessment-related
- Research Institution
  Tokyo Medical University
Clarification of in-vivo fracture mechanisms of ceramic acetabular liner toward the safety improvement
- Principal Investigator
  
  SHISHIDO Takaaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 26040:Structural materials and functional materials-related
- Research Institution
  Tokyo Medical University
A new diagnostic technology for degeneration of knee ligaments using Raman spectroscopy and its developmetnt toward practical applicationsPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Yasuhito
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Tokyo Medical University
Elucidation of the effects of antioxidant incorporation on molecular structure and mechanical properties in polyethylene hip joint prostheses
- Principal Investigator
  
  MASAOKA Toshinori
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Tokyo Medical University
Clarification of collagen degeneration mechanisms by NIR-Raman spectroscopy and development of a novel optical biopsy systemPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Yasuhito
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Tokyo Medical University
Effect of acetabular liner thickness on creep resistance in HXLPE for total joint replacement: deformation rate and molecular structure
- Principal Investigator
  
  YAMAMOTO Kengo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Tokyo Medical University

All 2019 2016 2015 2014

All Journal Article Presentation

[Journal Article] A New Method for Diagnosing Biochemical Abnormalities of Anterior Cruciate Ligament (ACL) in Human Knees: A Raman Spectroscopic Study2019
- Author(s)
  Matsunaga R, Takahashi Y, Takahashi RH, Nagao T, Shishido T, Tateiwa T, Pezzotti G, Yamamoto K.
- Journal Title
  
  Acta Biomaterialia
  
  Volume: 99 Pages: 284-294
- DOI
  10.1016/j.actbio.2019.09.016
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08524, KAKENHI-PROJECT-17K08705, KAKENHI-PROJECT-17K11029
[Journal Article] Size and thickness effect on creep deformation of conventional and vitamin E-diffused highly crosslinked UHMWPE in total hip arthroplasty2016
- Author(s)
  Yasuhito Takahashi , Toshiyuki Tateiwa, Takaaki Shishido, Toshinori Masaoka, Kosuke Kubo, Kengo Yamamoto
- Journal Title
  
  Journal of the Mechanical Behavior of Biomedical Materials
  
  Volume: 印刷中 Pages: 399-406
- DOI
  10.1016/j.jmbbm.2016.05.020
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462383
[Journal Article] Improved resistance to neck-liner impingement in second-generation highly crosslinked polyethylene - The role of vitamin E and crosslinks2016
- Author(s)
  Takahashi Y, Tateiwa T, Pezzotti G, Shishido T, Masaoka T, Yamamoto K
- Journal Title
  
  The Journal of Arthroplasty
  
  Volume: 31 Issue: 12 Pages: 2926-2932
- DOI
  10.1016/j.arth.2016.05.049
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01316
[Journal Article] Do formalin fixation and freeze-thaw affect near-infrared Raman spectroscopy of cartilaginous tissue? - An ex vivo analysis of native human articular cartilage2015
- Author(s)
  Yasuhito Takahashi, Takaaki Shishido, Kengo Yamamoto, Yasunobu Sawaji, Jun NIshida, Giuseppe Pezzotti
- Journal Title
  
  Journal of Raman Spectroscopy
  
  Volume: 46 Issue: 11 Pages: 1166-1172
- DOI
  10.1002/jrs.4748
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462320
[Journal Article] Vitamin-E blended and infused highly cross-linked polyethylene for total hip arthroplasty: A comparison of three-dimensional crystalline morphology and strain recovery behavior2014
- Author(s)
  Yasuhito Takahashi, Toshinori Masaoka, Kengo Yamamoto, Takaaki Shishido, Toshiyuki Tateiwa, Kosuke Kubo, Giuseppe Pezzotti
- Journal Title
  
  Journal of the mechanical behavior of biomedical materials
  
  Volume: 36 Pages: 59-70
- DOI
  10.1016/j.jmbbm.2014.04.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462383
[Presentation] ヒト前十字靭帯の非侵襲診断に向けたレーザーラマン分光の応用2019
- Author(s)
  松永怜、高橋康仁、山本謙吾
- Organizer
  第11回日本関節鏡・膝・スポーツ整形外科学会（JOSKAS）
- Data Source
  KAKENHI-PROJECT-17K11029
[Presentation] ヒト前十字靭帯の非侵襲診断に向けた近赤外レーザーラマン分光の応用2019
- Author(s)
  松永怜、高橋康仁、高橋礼典、長尾俊孝、宍戸孝明、正岡利紀、立岩俊之、山本謙吾
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-17K11029
[Presentation] Vitamin E混合は高架橋UHMWPEライナーの微細構造および力学挙動に影響するのか？2016
- Author(s)
  高橋康仁、Giuseppe Pezzotti、宍戸孝明、正岡利紀、立岩俊之、久保宏介、山本謙吾
- Organizer
  第46回日本人工関節学会
- Place of Presentation
  グランフロント大阪
- Year and Date
  2016-02-26
- Data Source
  KAKENHI-PROJECT-25462383
[Presentation] Vitamin E混合は高架橋UHMWPEライナーの微細構造および力学挙動に影響するのか？2016
- Author(s)
  高橋康仁、Giuseppe Pezzotti、宍戸孝明、正岡利紀、立岩俊之、久保宏介、山本謙吾
- Organizer
  第46回日本人工関節学会
- Place of Presentation
  グランフロント大阪
- Year and Date
  2016-02-26
- Data Source
  KAKENHI-PROJECT-15K01316

1. YAMAMOTO Kengo (10246316)

# of Collaborated Projects: 9 results

# of Collaborated Products: 8 results
2. SHISHIDO Takaaki (70266500)

# of Collaborated Projects: 9 results

# of Collaborated Products: 7 results
3. TATEIWA Toshiyuki (00424630)

# of Collaborated Projects: 9 results

# of Collaborated Products: 6 results
4. MASAOKA Toshinori (70256270)

# of Collaborated Projects: 8 results

# of Collaborated Products: 5 results
5. 松永怜 (90459579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 澤地恭昇 (20571152)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 香取庸一 (40233837)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 石田常仁 (10453721)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 高橋礼典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAKAHASHI Yasuhito 高橋 康仁

Research Projects

Research Products

Co-Researchers

人工股関節周囲組織反応(ALTR)の病態解明に関する基礎的および臨床的検討

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

超長寿命型人工膝関節開発のためのデラミネーション破壊抑制に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

高度架橋ポリエチレン製人工股関節の超長期耐用性の実現を目指した材料設計の至適化

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A novel proposal for validating the durability of ceramic-composite artificial hip joints and improving its prediction accuracyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Clarification of in-vivo fracture mechanisms of ceramic acetabular liner toward the safety improvement

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A new diagnostic technology for degeneration of knee ligaments using Raman spectroscopy and its developmetnt toward practical applicationsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the effects of antioxidant incorporation on molecular structure and mechanical properties in polyethylene hip joint prostheses

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clarification of collagen degeneration mechanisms by NIR-Raman spectroscopy and development of a novel optical biopsy systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of acetabular liner thickness on creep resistance in HXLPE for total joint replacement: deformation rate and molecular structure

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A New Method for Diagnosing Biochemical Abnormalities of Anterior Cruciate Ligament (ACL) in Human Knees: A Raman Spectroscopic Study2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Size and thickness effect on creep deformation of conventional and vitamin E-diffused highly crosslinked UHMWPE in total hip arthroplasty2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Improved resistance to neck-liner impingement in second-generation highly crosslinked polyethylene - The role of vitamin E and crosslinks2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Do formalin fixation and freeze-thaw affect near-infrared Raman spectroscopy of cartilaginous tissue? - An ex vivo analysis of native human articular cartilage2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Vitamin-E blended and infused highly cross-linked polyethylene for total hip arthroplasty: A comparison of three-dimensional crystalline morphology and strain recovery behavior2014

Author(s)

TAKAHASHI Yasuhito 高橋康仁