Harada Akihito 原田哲仁

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HARADA AKIHITO 原田哲仁

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Researcher Number	60596823
Other IDs
Affiliation (Current)	2025: 九州大学, 医学研究院, 教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 九州大学, 生体防御医学研究所, 准教授 2015 – 2019: 九州大学, 生体防御医学研究所, 助教
Review Section/Research Field	Principal Investigator Complex systems / Biological Sciences / Basic Section 42030:Animal life science-related / Transformative Research Areas, Section (III) / Basic Section 43050:Genome biology-related / Medium-sized Section 48:Biomedical structure and function and related fields / Genome biology Except Principal Investigator Basic Section 56030:Urology-related / Transformative Research Areas, Section (III)
Keywords	Principal Investigator 単一細胞解析 / エピジェネティクス / マルチオミクス / 精子形成 / H3t / ヒストン置換 / クロマチン / シンギュラリティ / RNA-seq / ヒストンバリアント … More / 細胞競合 / 空間オミクス / ChIL-Seq / シンギュラリティー / ChIL-seq / 3D genome / ChIL / エピゲノム / ゲノム生物 / 生殖細胞 / 骨格筋分化 … More Except Principal Investigator 精子形成 / 無精子症 / トランスクリプトーム解析 / 精祖細胞 / トランスクリプトーム / プロミニンー１ / 自己組織化 / 自己最適化 / 自律性 / 多細胞生命システム / 細胞競合 / 網羅的遺伝子解析 / エストラジオール / テストステロン / 単一細胞トランスクリプトーム解析 Less

精子形成における体細胞型H3から精子型H3T/tへのヒストン置換の意義の解明Principal Investigator
- Principal Investigator
  
  原田哲仁
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  Kyushu University
無精子症における精巣内内分泌環境に着目した単一細胞トランスクリプトーム解析
- Principal Investigator
  
  白石晃司
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Yamaguchi University
位置情報を保持したシンギュラリティ細胞の遺伝子発現測定技術の開発Principal Investigator
- Principal Investigator
  
  原田哲仁
- Project Period (FY)
  2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kyushu University
Understanding multicellular autonomy by competitive cell-cell communications
- Principal Investigator
  
  井垣達吏
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kyoto University
細胞競合における細胞間相互作用を計測するための空間オミクス技術開発Principal Investigator
- Principal Investigator
  
  原田哲仁
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kyushu University
全能性獲得機構の解明のためのmulti-omics技術の開発Principal Investigator
- Principal Investigator
  
  原田哲仁
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Single cell transcriptome analysis in men with non-obstructive azoospermia
- Principal Investigator
  
  Koji Shiraishi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Yamaguchi University
単一細胞multi-omicsによるシンギュラリティー細胞同定技術の開発Principal Investigator
- Principal Investigator
  
  原田哲仁
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kyushu University
Chromatin Dynamics of the Testis-Specific Histone Variant H3T/tPrincipal Investigator
- Principal Investigator
  
  Harada Akihito
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43050:Genome biology-related
- Research Institution
  Kyushu University
Capture of three-dimensional structure by ultra-high resolution on single cellPrincipal Investigator
- Principal Investigator
  
  Harada Akihito
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 48:Biomedical structure and function and related fields
- Research Institution
  Kyushu University
生殖細胞におけるヒストンバリアントによるゲノムマーキング機構の解明Principal Investigator
- Principal Investigator
  
  原田哲仁
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Functional analysis of novel histone H3 variant H3mm7 in skeletal muscle differentiationPrincipal Investigator
- Principal Investigator
  
  HARADA AKIHITO
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Genome biology
- Research Institution
  Kyushu University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation Book Patent

[Book] Precision Medicine2023
- Author(s)
  富松航佑,原田哲仁
- Total Pages
  6
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-23K27087
[Book] 月刊細胞2023
- Author(s)
  原田哲仁，大川恭行
- Total Pages
  4
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PLANNED-21H05292
[Book] 生体の科学2023
- Author(s)
  原田哲仁, 富松航佑, 武千メイ, 大川恭行
- Total Pages
  5
- Publisher
  公益財団法人金原一郎記念医学医療振興財団・医学書院
- Data Source
  KAKENHI-PLANNED-21H05292
[Book] 月刊細胞2023
- Author(s)
  原田哲仁，大川恭行
- Total Pages
  4
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-23K27087
[Book] 生体の科学2023
- Author(s)
  原田哲仁, 富松航佑, 武千メイ, 大川恭行
- Total Pages
  5
- Publisher
  公益財団法人金原一郎記念医学医療振興財団・医学書院
- Data Source
  KAKENHI-PROJECT-23K27087
[Book] Precision Medicine2023
- Author(s)
  富松航佑, 原田哲仁
- Total Pages
  6
- Publisher
  北隆館
- Data Source
  KAKENHI-PLANNED-21H05292
[Book] Journal of Japanese Biochemical Society2021
- Author(s)
  原田哲仁，大川恭行
- Publisher
  日本生化学会
- Data Source
  KAKENHI-PLANNED-21H05292
[Book] 1細胞エピゲノム解析技術開発の最前線2021
- Author(s)
  大川恭行,原田哲仁,前原一満
- Total Pages
  6
- Publisher
  医歯薬出版株式会社週刊医学のあゆみ
- Data Source
  KAKENHI-PUBLICLY-20H05368
[Book] 1細胞エピゲノム解析技術開発の最前線2021
- Author(s)
  大川恭行,原田哲仁,前原一満
- Total Pages
  6
- Publisher
  医歯薬出版株式会社週刊医学のあゆみ
- Data Source
  KAKENHI-PUBLICLY-19H05425
[Book] Journal of Japanese Biochemical Society2021
- Author(s)
  原田哲仁，大川恭行
- Publisher
  日本生化学会
- Data Source
  KAKENHI-PROJECT-19H03211
[Book] 1細胞エピゲノム解析技術開発の最前線2021
- Author(s)
  大川恭行,原田哲仁,前原一満
- Total Pages
  6
- Publisher
  医歯薬出版株式会社週刊医学のあゆみ
- Data Source
  KAKENHI-PROJECT-19H03211
[Book] シングルセルでのエピゲノム情報の計測技術.2020
- Author(s)
  原田哲仁，大川恭行
- Total Pages
  8
- Publisher
  羊土社実験医学
- Data Source
  KAKENHI-PROJECT-19H03211
[Book] 骨格筋研究のための最先端解析技術.2020
- Author(s)
  原田哲仁，大川恭行
- Total Pages
  7
- Publisher
  羊土社実験医学
- Data Source
  KAKENHI-PUBLICLY-19H05425
[Book] 骨格筋研究のための最先端解析技術.2020
- Author(s)
  原田哲仁，大川恭行
- Total Pages
  7
- Publisher
  羊土社実験医学
- Data Source
  KAKENHI-PUBLICLY-20H05368
[Book] 骨格筋研究のための最先端解析技術.2020
- Author(s)
  原田哲仁，大川恭行
- Total Pages
  7
- Publisher
  羊土社実験医学
- Data Source
  KAKENHI-PROJECT-19H03211
[Book] シングルセルでのエピゲノム情報の計測技術.2020
- Author(s)
  原田哲仁，大川恭行
- Total Pages
  8
- Publisher
  羊土社実験医学
- Data Source
  KAKENHI-PUBLICLY-19H05425
[Book] シングルセルでのエピゲノム情報の計測技術.2020
- Author(s)
  原田哲仁，大川恭行
- Total Pages
  8
- Publisher
  羊土社実験医学
- Data Source
  KAKENHI-PUBLICLY-20H05368
[Book] シングルセルゲノミクス「クロマチン挿入標識法（ChIL）による単一細胞エピゲノム解析」2019
- Author(s)
  原田哲仁, 大川恭行
- Total Pages
  219
- Publisher
  羊土社
- ISBN
  9784758103831
- Data Source
  KAKENHI-PROJECT-18K19432
[Book] ヒストンバリアントによるエピゲノム制御2015
- Author(s)
  原田哲仁
- Total Pages
  4
- Publisher
  ㈱メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-15K18457
[Journal Article] Production of a Monoclonal Antibody for Histone H2b Isoform H2b3b2024
- Author(s)
  Egashira Saki、Tachibana Taro、Nakamura Mako、Ohkawa Yasuyuki、Harada Akihito
- Journal Title
  
  Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
  
  Volume: 43 Issue: 2 Pages: 75-80
- DOI
  10.1089/mab.2023.0025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19275, KAKENHI-PUBLICLY-22H04676, KAKENHI-PLANNED-21H05292, KAKENHI-PROJECT-23H00372, KAKENHI-PROJECT-23K27087
[Journal Article] Precise immunofluorescence canceling for highly multiplexed imaging capturing specific cell state2023
- Author(s)
  Tomimatsu Kosuke、Fujii Takeru、Bise Ryoma、Hosoda Kazufumi、Taniguchi Yosuke、Ochiai Hiroshi、Ohishi Hiroaki、Ando Kanta、Minami Ryoma、Tanaka Kaori、Tachibana Taro、Mori Seiichi、Harada Akihito、Maehara Kazumitsu、Nagasaki Masao、Uchida Seiichi、Kimura Hiroshi、Narita Masashi、Ohkawa Yasuyuki
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2023.10.17.561810
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15084, KAKENHI-PROJECT-22K19275, KAKENHI-PROJECT-22K19314, KAKENHI-PUBLICLY-22H04676, KAKENHI-PUBLICLY-22H04694, KAKENHI-PLANNED-21H05292, KAKENHI-PUBLICLY-23H04286, KAKENHI-PROJECT-23H00372, KAKENHI-PROJECT-23K23872, KAKENHI-PROJECT-23K24795, KAKENHI-PROJECT-23K27087
[Journal Article] FOXK1 promotes nonalcoholic fatty liver disease by mediating mTORC1-dependent inhibition of hepatic fatty acid oxidation.2023
- Author(s)
  Fujinuma S, Nakatsumi H, Shimizu H, Sugiyama S, Harada A, Goya T, Tanaka M, Kohjima M, Takahashi M, Izumi Y, Yagi M, Kang D, Kaneko M, Shigeta M, Bamba T, Ohkawa Y, Nakayama KI*.
- Journal Title
  
  Cell Reports
  
  Volume: 42(5) Issue: 5 Pages: 112530-112530
- DOI
  10.1016/j.celrep.2023.112530
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K18924, KAKENHI-PROJECT-21K07155, KAKENHI-PROJECT-22K19275, KAKENHI-PUBLICLY-22H04676, KAKENHI-PLANNED-21H05292, KAKENHI-PLANNED-22H05185, KAKENHI-PROJECT-23H00372, KAKENHI-PROJECT-23K27087
[Journal Article] Photo-isolation chemistry for high-resolution and deep spatial transcriptome with mouse tissue sections2022
- Author(s)
  Honda Mizuki、Kimura Ryuichi、Harada Akihito、Maehara Kazumitsu、Tanaka Kaori、Ohkawa Yasuyuki、Oki Shinya
- Journal Title
  
  STAR Protocols
  
  Volume: 3 Issue: 2 Pages: 101346-101346
- DOI
  10.1016/j.xpro.2022.101346
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09522, KAKENHI-PROJECT-22K19275, KAKENHI-PLANNED-21H05292, KAKENHI-PUBLICLY-21H05755, KAKENHI-PUBLICLY-22H05594, KAKENHI-PROJECT-20H00456, KAKENHI-PUBLICLY-21H00232, KAKENHI-PUBLICLY-22H04676, KAKENHI-PUBLICLY-22H04696, KAKENHI-PROJECT-19H03424
[Journal Article] Uterus-specific transcriptional regulation underlies eggshell pigment production in Japanese quail.2022
- Author(s)
  Ishishita S, Kitahara S, Takahashi M, Iwasaki S, Tatsumoto S, Hara I, Kaneko Y, Kinoshita K, Yamaguchi K, Harada A, Ohmori Y, Ohkawa Y, Go Y, Shigenobu S, Matsuda Y, Suzuki T.
- Journal Title
  
  PLoS One.
  
  Volume: 17
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03211
[Journal Article] Recent advances in single-cell epigenomics.2021
- Author(s)
  Harada A, Kimura H, Ohkawa Y.
- Journal Title
  
  Curr Opin Struct Biol.
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03211
[Journal Article] Discovery of anti-inflammatory physiological peptides that promote tissue repair by reinforcing epithelial barrier formation2021
- Author(s)
  Oda Y., Takahashi C., Harada S., Nakamura S., Sun D., Kiso K., Urata Y., Miyachi H., Fujiyoshi Y., Honigmann A., Uchida S., Ishihama, Y. and Toyoshima, F.
- Journal Title
  
  Science Advances
  
  Volume: 7 Issue: 47 Pages: 1-14
- DOI
  10.1126/sciadv.abj6895
- NAID
  120007169950
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-21H05283, KAKENHI-PROJECT-20H00451, KAKENHI-PROJECT-21J13083, KAKENHI-PROJECT-16H06280, KAKENHI-PLANNED-21H05286
[Journal Article] Modeling population size independent tissue epigenomes by ChIL‐seq with single thin sections2021
- Author(s)
  Maehara Kazumitsu、Tomimatsu Kosuke、Harada Akihito、Tanaka Kaori、Sato Shoko、Fukuoka Megumi、Okada Seiji、Handa Tetsuya、Kurumizaka Hitoshi、Saitoh Noriko、Kimura Hiroshi、Ohkawa Yasuyuki
- Journal Title
  
  Molecular Systems Biology
  
  Volume: 17 Issue: 11 Pages: 8934-8946
- DOI
  10.15252/msb.202110323
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05527, KAKENHI-PLANNED-18H05534, KAKENHI-PUBLICLY-20H05368, KAKENHI-PUBLICLY-21H00430, KAKENHI-ORGANIZER-21H05283, KAKENHI-PROJECT-20H00449, KAKENHI-PROJECT-20H03520, KAKENHI-PLANNED-18H05531
[Journal Article] Genome-wide analysis of chromatin structure changes upon MyoD binding in proliferative myoblasts during the cell cycle2021
- Author(s)
  Wu Qianmei、Fujii Takeru、Harada Akihito、Tomimatsu Kosuke、Miyawaki-Kuwakado Atsuko、Fujita Masatoshi、Maehara Kazumitsu、Ohkawa Yasuyuki
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: - Issue: 6 Pages: 653-661
- DOI
  10.1093/jb/mvab001
- NAID
  40022687719
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05527, KAKENHI-PUBLICLY-19H04970, KAKENHI-PUBLICLY-19H05244, KAKENHI-PUBLICLY-19H05425, KAKENHI-PUBLICLY-20H05393, KAKENHI-PROJECT-19H03158, KAKENHI-PROJECT-19K07664, KAKENHI-PROJECT-20K21398, KAKENHI-PUBLICLY-20H04846, KAKENHI-PUBLICLY-20H05368, KAKENHI-PUBLICLY-21H00232, KAKENHI-PUBLICLY-21H00430, KAKENHI-PROJECT-20H00456, KAKENHI-PROJECT-19H03211
[Journal Article] Chromatin structure-dependent histone incorporation revealed by a genome-wide deposition assay2021
- Author(s)
  Hiroaki Tachiwana, Mariko Dacher, Kazumitsu Maehara, Akihito Harada, Yosuke Seto, Ryohei Katayama, Yasuyuki Ohkawa, Hiroshi Kimura, Hitoshi Kurumizaka, Noriko Saitoh
- Journal Title
  
  eLife
  
  Volume: 10
- DOI
  10.7554/elife.66290
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H04970, KAKENHI-PUBLICLY-20H05393, KAKENHI-PROJECT-19H03158, KAKENHI-PROJECT-20K21398, KAKENHI-PROJECT-20K21554, KAKENHI-PROJECT-20K16370, KAKENHI-PLANNED-18H05527, KAKENHI-PLANNED-18H05534, KAKENHI-PUBLICLY-20H04846, KAKENHI-PUBLICLY-20H05397, KAKENHI-PUBLICLY-21H00232, KAKENHI-PUBLICLY-21H00430, KAKENHI-PROJECT-20H00449, KAKENHI-PROJECT-20H00456, KAKENHI-PROJECT-19H03211, KAKENHI-PROJECT-19H03524, KAKENHI-PROJECT-20H03520, KAKENHI-PROJECT-20K06496, KAKENHI-PROJECT-16H06279, KAKENHI-PLANNED-18H05531
[Journal Article] Modeling population size independent tissue epigenomes by ChIL-seq with single thin sections.2021
- Author(s)
  Maehara K, Tomimatsu K, Harada A, Tanaka K, Sato S, Fukuoka M, Okada S, Handa T, Kurumizaka H, Saitoh N, Kimura H, Ohkawa Y.
- Journal Title
  
  Mol Syst Biol.
  
  Volume: 17
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03211
[Journal Article] High-depth spatial transcriptome analysis by photo-isolation chemistry.2021
- Author(s)
  Honda M, Oki S, Kimura R, Harada A, Maehara K, Tanaka K, Meno C, Ohkawa Y.
- Journal Title
  
  Nat Commun.
  
  Volume: 12 Issue: 1 Pages: 4416-4416
- DOI
  10.1038/s41467-021-24691-8
- NAID
  120007141968
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21398, KAKENHI-PUBLICLY-20H04846, KAKENHI-PUBLICLY-20H05368, KAKENHI-PUBLICLY-20H05393, KAKENHI-PUBLICLY-21H00232, KAKENHI-PUBLICLY-21H00430, KAKENHI-PROJECT-20H00456, KAKENHI-PROJECT-19H03158, KAKENHI-PROJECT-19H03211, KAKENHI-PROJECT-19H03424
[Journal Article] Uterus-specific transcriptional regulation underlies eggshell pigment production in Japanese quail.2021
- Author(s)
  1.Ishishita S, Kitahara S, Takahashi M, Iwasaki S, Tatsumoto S, Hara I, Kaneko Y, Kinoshita K, Yamaguchi K, Harada A, Ohmori Y, Ohkawa Y, Go Y, Shigenobu S, Matsuda Y, Suzuki T.
- Journal Title
  
  PLoS One.
  
  Volume: 17
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21H05292
[Journal Article] Recent advances in single-cell epigenomics.2021
- Author(s)
  2.Harada A, Kimura H, Ohkawa Y.
- Journal Title
  
  Curr Opin Struct Biol.
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21H05292
[Journal Article] Transcriptome analysis of gene expression changes upon enzymatic dissociation in skeletal myoblasts.2021
- Author(s)
  Miyawaki-Kuwakado A, Wu Q, Harada A, Tomimatsu K, Fujii T, Maehara K, Ohkawa Y.
- Journal Title
  
  Genes Cells.
  
  Volume: 26 Issue: 7 Pages: 530-540
- DOI
  10.1111/gtc.12870
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07664, KAKENHI-PROJECT-20K21398, KAKENHI-PUBLICLY-20H04846, KAKENHI-PUBLICLY-20H05368, KAKENHI-PUBLICLY-21H00232, KAKENHI-PUBLICLY-21H00430, KAKENHI-PROJECT-20H00456, KAKENHI-PROJECT-19H03158, KAKENHI-PROJECT-19H03211
[Journal Article] Modeling population size independent tissue epigenomes by ChIL-seq with single thin sections.2021
- Author(s)
  3.Maehara K, Tomimatsu K, Harada A, Tanaka K, Sato S, Fukuoka M, Okada S, Handa T, Kurumizaka H, Saitoh N, Kimura H, Ohkawa Y.
- Journal Title
  
  Mol Syst Biol.
  
  Volume: 17
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21H05292
[Journal Article] Targeted inhibition of EPAS1-driven IL-31 production by a small-molecule compound.2021
- Author(s)
  Kamikaseda Y, Uruno T, Kunimura K, Harada A, Saiki K, Oisaki K, Sakata D, Nakahara T, Kido-Nakahara M, Kanai M, Nakamura S, Ohkawa Y, Furue M, Fukui Y.
- Journal Title
  
  J Allergy Clin Immunol.
  
  Volume: 148 Issue: 2 Pages: 633-638
- DOI
  10.1016/j.jaci.2021.03.029
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21398, KAKENHI-PUBLICLY-20H04846, KAKENHI-PUBLICLY-20H05368, KAKENHI-PUBLICLY-21H00232, KAKENHI-PUBLICLY-21H00430, KAKENHI-PROJECT-19H00983, KAKENHI-PROJECT-20H00456, KAKENHI-PROJECT-19H03211, KAKENHI-PROJECT-21H02430, KAKENHI-PROJECT-18H02406
[Journal Article] Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cells2020
- Author(s)
  Ochiai Hiroshi、Hayashi Tetsutaro、Umeda Mana、Yoshimura Mika、Harada Akihito、Shimizu Yukiko、Nakano Kenta、Saitoh Noriko、Liu Zhe、Yamamoto Takashi、Okamura Tadashi、Ohkawa Yasuyuki、Kimura Hiroshi、Nikaido Itoshi
- Journal Title
  
  Science Advances
  
  Volume: 6 Issue: 25
- DOI
  10.1126/sciadv.aaz6699
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06612, KAKENHI-PROJECT-20K21398, KAKENHI-PLANNED-18H05527, KAKENHI-PUBLICLY-19H05244, KAKENHI-PUBLICLY-19H05425, KAKENHI-PUBLICLY-20H04846, KAKENHI-PUBLICLY-20H05368, KAKENHI-PROJECT-17H01409, KAKENHI-PROJECT-20H00456, KAKENHI-PROJECT-19H03211, KAKENHI-PROJECT-20H03520, KAKENHI-PROJECT-18K19310, KAKENHI-PLANNED-18H05531, KAKENHI-PROJECT-19H03424
[Journal Article] Chromatin integration labeling for mapping DNA-binding proteins and modifications with low input.2020
- Author(s)
  Tetsuya Handa, Akihito Harada, Kazumitsu Maehara, Shoko Sato, Masaru Nakao, Naoki Goto, Hitoshi Kurumizaka, Yasuyuki Ohkawa, Hiroshi Kimura.
- Journal Title
  
  Nat Protoc.
  
  Volume: 15 Issue: 10 Pages: 3334-3360
- DOI
  10.1038/s41596-020-0375-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21398, KAKENHI-PLANNED-18H05534, KAKENHI-PUBLICLY-19H04970, KAKENHI-PUBLICLY-19H05244, KAKENHI-PUBLICLY-19H05425, KAKENHI-PUBLICLY-20H04846, KAKENHI-PUBLICLY-20H05368, KAKENHI-PUBLICLY-20H05393, KAKENHI-PROJECT-17H01417, KAKENHI-PROJECT-20H00456, KAKENHI-PROJECT-19H03158, KAKENHI-PROJECT-19H03211, KAKENHI-PROJECT-17K17719, KAKENHI-PROJECT-19H03424
[Journal Article] Subnuclear gene positioning through lamina association affects copper tolerance2020
- Author(s)
  Sakamoto Yuki、Sato Mayuko、Sato Yoshikatsu、Harada Akihito、Suzuki Takamasa、Goto Chieko、Tamura Kentaro、Toyooka Kiminori、Kimura Hiroshi、Ohkawa Yasuyuki、Hara-Nishimura Ikuko、Takagi Shingo、Matsunaga Sachihiro
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 5914-5914
- DOI
  10.1038/s41467-020-19621-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06283, KAKENHI-PROJECT-20K21398, KAKENHI-PLANNED-18H05527, KAKENHI-PUBLICLY-19H05244, KAKENHI-PUBLICLY-19H05425, KAKENHI-PUBLICLY-20H04846, KAKENHI-PUBLICLY-20H05368, KAKENHI-PROJECT-20H00456, KAKENHI-PROJECT-19H03211, KAKENHI-PROJECT-19H03259, KAKENHI-PROJECT-16H06280, KAKENHI-PROJECT-15H05776, KAKENHI-ORGANIZER-19H05670, KAKENHI-PLANNED-20H05911, KAKENHI-PROJECT-19H03424
[Journal Article] Biochemical analysis of nucleosome targeting by Tn5 transposase2019
- Author(s)
  Sato S, Arimura Y, Kujirai T, Harada A, Maehara K, Nogami J, Ohkawa Y, Kurumizaka H.
- Journal Title
  
  Open Biol.
  
  Volume: 9 Issue: 8 Pages: 190116-190116
- DOI
  10.1098/rsob.190116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04802, KAKENHI-PUBLICLY-18H04904, KAKENHI-PLANNED-18H05534, KAKENHI-PUBLICLY-19H04970, KAKENHI-PUBLICLY-19H05244, KAKENHI-PUBLICLY-19H05425, KAKENHI-PROJECT-17H01408, KAKENHI-PROJECT-17H03608, KAKENHI-PROJECT-19H03158, KAKENHI-PROJECT-19H03211, KAKENHI-PROJECT-18K19432, KAKENHI-PROJECT-19K21177, KAKENHI-PROJECT-19H03424
[Journal Article] Chromatin-bound CRM1 recruits SET-Nup214 and NPM1c onto HOX clusters causing aberrant HOX expression in leukemia cells.2019
- Author(s)
  Oka M, Mura S, Otani M, Miyamoto Y, Nogami J, Maehara K, Harada A, Tachibana T, Yoneda Y, Ohkawa Y
- Journal Title
  
  Elife
  
  Volume: 8
- DOI
  10.7554/elife.46667
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04802, KAKENHI-PUBLICLY-18H04904, KAKENHI-PLANNED-18H05527, KAKENHI-PUBLICLY-19H04970, KAKENHI-PUBLICLY-19H05244, KAKENHI-PUBLICLY-19H05425, KAKENHI-PROJECT-17H03608, KAKENHI-PROJECT-17H03679, KAKENHI-PROJECT-19H03158, KAKENHI-PROJECT-19H03211, KAKENHI-PROJECT-18K19432, KAKENHI-PROJECT-19H03424
[Journal Article] Sustained expression of HeyL is critical for the proliferation of muscle stem cells in overloaded muscle.2019
- Author(s)
  Fukuda S, Kaneshige A, Kaji T, Noguchi YT, Takemoto Y, Zhang L, Tsujikawa K, Kokubo H, Uezumi A, Maehara K, Harada A, Ohkawa Y, Fukada SI.
- Journal Title
  
  eLife
  
  Volume: 8
- DOI
  10.7554/elife.48284
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19740, KAKENHI-PUBLICLY-18H04802, KAKENHI-PUBLICLY-18H04904, KAKENHI-PUBLICLY-19H04970, KAKENHI-PUBLICLY-19H05244, KAKENHI-PUBLICLY-19H05425, KAKENHI-PROJECT-17H03608, KAKENHI-PROJECT-19H03158, KAKENHI-PROJECT-19H03211, KAKENHI-PROJECT-19H04000, KAKENHI-PROJECT-18K19432, KAKENHI-PROJECT-19H03424
[Journal Article] Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration2018
- Author(s)
  Harada Akihito、Maehara Kazumitsu、Ono Yusuke、Taguchi Hiroyuki、Yoshioka Kiyoshi、Kitajima Yasuo、Xie Yan、Sato Yuko、Iwasaki Takeshi、Nogami Jumpei、Okada Seiji、Komatsu Tetsuro、Semba Yuichiro、Takemoto Tatsuya、Kimura Hiroshi、Kurumizaka Hitoshi、Ohkawa Yasuyuki
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 1400-1400
- DOI
  10.1038/s41467-018-03845-1
- NAID
  120006949474
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K16486, KAKENHI-PUBLICLY-16H01219, KAKENHI-PUBLICLY-16H01550, KAKENHI-PUBLICLY-16H01577, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25116005, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-16J00431, KAKENHI-PROJECT-16K18479, KAKENHI-PUBLICLY-18H04802, KAKENHI-PUBLICLY-18H04904, KAKENHI-PROJECT-17H01408, KAKENHI-PROJECT-16H05450, KAKENHI-PROJECT-17H03607, KAKENHI-PROJECT-17H03608, KAKENHI-PROJECT-16K15668, KAKENHI-PROJECT-17K19356, KAKENHI-PROJECT-16J09948
[Journal Article] A chromatin integration labelling method enables epigenomic profiling with lower input2018
- Author(s)
  Harada Akihito、Maehara Kazumitsu、Handa Tetsuya、Arimura Yasuhiro、Nogami Jumpei、Hayashi-Takanaka Yoko、Shirahige Katsuhiko、Kurumizaka Hitoshi、Kimura Hiroshi、Ohkawa Yasuyuki
- Journal Title
  
  Nature Cell Biology
  
  Volume: 21 Issue: 2 Pages: 287-296
- DOI
  10.1038/s41556-018-0248-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19432, KAKENHI-PROJECT-17K17719, KAKENHI-INTERNATIONAL-15K21761, KAKENHI-ORGANIZER-15H05970, KAKENHI-PLANNED-15H05976, KAKENHI-PUBLICLY-18H04802, KAKENHI-PUBLICLY-18H04904, KAKENHI-PLANNED-18H05527, KAKENHI-PLANNED-18H05534, KAKENHI-PROJECT-17H01408, KAKENHI-PROJECT-17H01417, KAKENHI-PROJECT-17H03608, KAKENHI-PROJECT-17K19356
[Journal Article] Sensitive detection of fluorescence in western blotting by merging images2018
- Author(s)
  Kondo Yukari、Higa Shinichiro、Iwasaki Takeshi、Matsumoto Tomoya、Maehara Kazumitsu、Harada Akihito、Baba Yoshihiro、Fujita Masatoshi、Ohkawa Yasuyuki
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 1 Pages: 0191532-0191532
- DOI
  10.1371/journal.pone.0191532
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01219, KAKENHI-PUBLICLY-16H01550, KAKENHI-PUBLICLY-16H01577, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-16K18479, KAKENHI-PUBLICLY-18H04802, KAKENHI-PROJECT-17H03608, KAKENHI-PROJECT-18H02626, KAKENHI-PROJECT-16K15217, KAKENHI-PROJECT-17K19356
[Journal Article] Roles of histone H3.5 in human spermatogenesis and spermatogenic disorders2017
- Author(s)
  Shiraishi K.、Shindo A.、Harada A.、Kurumizaka H.、Kimura H.、Ohkawa Y.、Matsuyama H.
- Journal Title
  
  Andrology
  
  Volume: 6 Issue: 1 Pages: 158-165
- DOI
  10.1111/andr.12438
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19356, KAKENHI-PUBLICLY-16H01219, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-17H03608, KAKENHI-PROJECT-15K10642
[Journal Article] Testis-Specific Histone Variant H3t Gene Is Essential for Entry into Spermatogenesis2017
- Author(s)
  Ueda J., Harada A., Urahama T., Machida S., Maehara K., Hada M., Makino Y., Nogami J., Horikoshi N., Osakabe A., Taguchi H., Tanaka H., Tachiwana H., Yao T., Yamada M., Iwamoto T., Isotani A., Ikawa M., Tachibana T., Okada Y., Kimura H., Ohkawa Y., Kurumizaka H., Yamagata K.
- Journal Title
  
  Cell Reports
  
  Volume: 18(3) Issue: 3 Pages: 593-600
- DOI
  10.1016/j.celrep.2016.12.065
- NAID
  120006957416
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-15H05976, KAKENHI-PUBLICLY-16H01219, KAKENHI-PUBLICLY-16H01550, KAKENHI-PUBLICLY-16H01577, KAKENHI-PLANNED-25112007, KAKENHI-PLANNED-25116002, KAKENHI-PLANNED-25116005, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-25250014, KAKENHI-PROJECT-15J06922, KAKENHI-PROJECT-16J09361, KAKENHI-PROJECT-25712035, KAKENHI-PROJECT-15K18457, KAKENHI-PROJECT-16K08748, KAKENHI-PROJECT-16K18473, KAKENHI-PROJECT-16K18479, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-16K07099, KAKENHI-PUBLICLY-16H01319, KAKENHI-PROJECT-17J06605
[Journal Article] Chd2 regulates chromatin for proper gene expression toward differentiation in mouse embryonic stem cells2017
- Author(s)
  Semba Yuichiro、Harada Akihito、Maehara Kazumitsu、Oki Shinya、Meno Chikara、Ueda Jun、Yamagata Kazuo、Suzuki Atsushi、Onimaru Mitsuho、Nogami Jumpei、Okada Seiji、Akashi Koichi、Ohkawa Yasuyuki
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 45 Issue: 15 Pages: 8758-8772
- DOI
  10.1093/nar/gkx475
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15668, KAKENHI-PROJECT-17K19356, KAKENHI-PROJECT-17K19603, KAKENHI-PROJECT-26291051, KAKENHI-PUBLICLY-16H01219, KAKENHI-PUBLICLY-16H01550, KAKENHI-PUBLICLY-16H01577, KAKENHI-PLANNED-16H06530, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-16H06391, KAKENHI-PROJECT-17H01571, KAKENHI-PROJECT-16H05450, KAKENHI-PROJECT-17H03608, KAKENHI-PROJECT-16K18479, KAKENHI-PUBLICLY-16H01319, KAKENHI-PROJECT-16K07099, KAKENHI-PROJECT-16H01850, KAKENHI-PUBLICLY-17H05623
[Journal Article] Crystal Structure and Characterization of Novel Human Histone H3 Variants, H3.6, H3.7, and H3.82017
- Author(s)
  Taguchi H, Xie Y, Horikoshi N, Maehara K, Harada A, Nogami J, Sato K, Arimura Y, Osakabe A, Kujirai T, Iwasaki T, Semba Y, Tachibana T, Kimura H, Ohkawa Y, Kurumizaka H.
- Journal Title
  
  Biochemistry
  
  Volume: 56 Issue: 16 Pages: 2184-2196
- DOI
  10.1021/acs.biochem.6b01098
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-25116005, KAKENHI-PROJECT-17K19356, KAKENHI-PROJECT-17K15043, KAKENHI-PUBLICLY-16H01219, KAKENHI-PUBLICLY-16H01550, KAKENHI-PUBLICLY-16H01577, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25116002, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-17H03608, KAKENHI-PROJECT-15J06807, KAKENHI-PROJECT-16J09361, KAKENHI-PROJECT-16K18479
[Journal Article] The requirement of Mettl3-promoted MyoD mRNA maintenance in proliferative myoblasts for skeletal muscle differentiation2017
- Author(s)
  Kudou Kensuke、Komatsu Tetsuro、Nogami Jumpei、Maehara Kazumitsu、Harada Akihito、Saeki Hiroshi、Oki Eiji、Maehara Yoshihiko、Ohkawa Yasuyuki
- Journal Title
  
  Open Biology
  
  Volume: 7 Issue: 9 Pages: 170119-170119
- DOI
  10.1098/rsob.170119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19356, KAKENHI-PUBLICLY-16H01219, KAKENHI-PUBLICLY-16H01550, KAKENHI-PUBLICLY-16H01577, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-17H03608, KAKENHI-PROJECT-17H06943, KAKENHI-PROJECT-16K18479
[Journal Article] Temporal regulation of chromatin during myoblast differentiation2017
- Author(s)
  Harada Akihito、Ohkawa Yasuyuki、Imbalzano Anthony N.
- Journal Title
  
  Seminars in Cell & Developmental Biology
  
  Volume: 72 Pages: 77-86
- DOI
  10.1016/j.semcdb.2017.10.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19356, KAKENHI-PUBLICLY-16H01219, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-17H03608
[Journal Article] Periostin Promotes Scar Formation through the Interaction between Pericytes and Infiltrating Monocytes/Macrophages after Spinal Cord Injury.2017
- Author(s)
  Yokota K, Kobayakawa K, Saito T, Hara M, Kijima K, Ohkawa Y, Harada A, Okazaki K, Ishihara K, Yoshida S, Kudo A, Iwamoto Y, Okada S.
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  Am J Pathol.
  
  Volume: 187 Issue: 3 Pages: 639-653
- DOI
  10.1016/j.ajpath.2016.11.010
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01219, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-16H05450, KAKENHI-PROJECT-15K18457, KAKENHI-PROJECT-16K20059, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-16K15668
[Journal Article] Identification of Immunoglobulin Gene Sequences from a Small Read Number of mRNA-Seq Using Hybridomas.2016
- Author(s)
  Kuniyoshi Y, Maehara K, Iwasaki T, Hayashi M, Semba Y, Fujita M, Sato Y, Kimura H, Harada A, Ohkawa Y.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 10 Pages: e0165473-e0165473
- DOI
  10.1371/journal.pone.0165473
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01219, KAKENHI-PUBLICLY-16H01550, KAKENHI-PUBLICLY-16H01577, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-26290064, KAKENHI-PROJECT-15K18457, KAKENHI-PROJECT-16K18479, KAKENHI-ORGANIZER-25112001
[Journal Article] Histone H3.5 forms an unstable nucleosome and accumulates around transcription start sites in human testis.2016
- Author(s)
  Urahama T, Harada A, Maehara K, Horikoshi N, Sato K, Sato Y, Shiraishi K, Sugino N, Osakabe A, Tachiwana H, Kagawa W, Kimura H, Ohkawa Y, Kurumizaka H.
- Journal Title
  
  Epigenetics Chromatin
  
  Volume: 9 Issue: 1 Pages: 1-16
- DOI
  10.1186/s13072-016-0051-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K18457, KAKENHI-PLANNED-25116002, KAKENHI-PLANNED-25116005, KAKENHI-PLANNED-25116010, KAKENHI-PUBLICLY-26116521, KAKENHI-PROJECT-15J06922, KAKENHI-PROJECT-13J04024, KAKENHI-PROJECT-26830128, KAKENHI-PROJECT-26840025, KAKENHI-PROJECT-26290064, KAKENHI-PROJECT-15K10642
[Journal Article] Histone H4 lysine 20 acetylation is associated with gene repression in human cells.2016
- Author(s)
  Kaimori, J. Y., Maehara, K., Hayashi-Takanaka, Y., Harada, A., Fukuda, M., Yamamoto, S., Ichimaru, N., Umehara, T., Yokoyama, S., Matsuda, R., Ikura, T., Nagao, K., Obuse, C., Nozaki, N., Takahara, S., Takao, T., Ohkawa, Y., Kimura, H., and Isaka, Y.
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  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 24318-24318
- DOI
  10.1038/srep24318
- NAID
  120005770760
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06942, KAKENHI-PUBLICLY-15H01462, KAKENHI-PLANNED-25116005, KAKENHI-PROJECT-25503002, KAKENHI-PROJECT-25670410, KAKENHI-PROJECT-26291071, KAKENHI-PUBLICLY-16H01219, KAKENHI-PUBLICLY-16H01307, KAKENHI-PUBLICLY-16H01550, KAKENHI-PUBLICLY-16H01577, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-16H04739, KAKENHI-PROJECT-26281020, KAKENHI-PROJECT-26290064, KAKENHI-PROJECT-26293166, KAKENHI-PROJECT-15K12203, KAKENHI-PROJECT-26650002, KAKENHI-PROJECT-15K18457, KAKENHI-PROJECT-16K18479, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25116004
[Journal Article] Relationship between the risk for a shrimp allergy and freshness or cooking2015
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  Masakatsu USUI, Akihito HARADA, Shinya YASUMOTO, Yoshimasa SUGIURA, Anri NISHIDAI, Maria IKARASHI, Honami TAKABA, Taiko MIYASAKI, Hiroyuki AZAKAMI, and Masakazu KONDO
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  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 未定 Issue: 10 Pages: 1698-1701
- DOI
  10.1080/09168451.2015.1045830
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26560077, KAKENHI-PROJECT-15K18457, KAKENHI-PROJECT-25450103
[Journal Article] Tissue-specific expression of histone H3 variants diversified after species separation.2015
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  Maehara K, Harada A, Sato Y, Matsumoto M, Nakayama KI, Kimura H, Ohkawa Y.
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  Epigenetics Chromatin
  
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  10.1186/s13072-015-0027-3
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K18457, KAKENHI-PUBLICLY-15H01407, KAKENHI-PLANNED-25116005, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-13J04024, KAKENHI-PROJECT-25290078, KAKENHI-PROJECT-26290064, KAKENHI-PUBLICLY-26116721
[Journal Article] Chd5 Regulates MuERV-L/MERVL Expression in Mouse Embryonic Stem Cells Via H3K27me3 Modification and Histone H3.1/H3.2.2015
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  Hayashi M, Maehara K, Harada A, Semba Y, Kudo K, Takahashi H, Oki S, Meno C, Ichiyanagi K, Akashi K, Ohkawa Y.
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  J Cell Biochem
  
  Volume: 117 Issue: 3 Pages: 780-792
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  10.1002/jcb.25368
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15365, KAKENHI-PROJECT-15K18457, KAKENHI-PLANNED-24118002, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-13J04024, KAKENHI-PROJECT-25503003, KAKENHI-PROJECT-26670130, KAKENHI-PROJECT-25840087, KAKENHI-PROJECT-26290064, KAKENHI-PROJECT-26291051, KAKENHI-PROJECT-15H04701
[Journal Article] Distribution of histone H4 modifications as revealed by a panel of specific monoclonal antibodies.2015
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  Hayashi-Takanaka Y., Maehara K., Harada A., Umehara T., Yokoyama S., Obuse C., Ohkawa Y., Nozaki N., Kimura H.
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  Chromosome Res.
  
  Volume: 23 Issue: 4 Pages: 753-766
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  10.1007/s10577-015-9486-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26650002, KAKENHI-PROJECT-15K18457, KAKENHI-PLANNED-25116005, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-13J04024, KAKENHI-PROJECT-25503002, KAKENHI-PROJECT-26290064, KAKENHI-PROJECT-26291071, KAKENHI-PLANNED-25116004
[Patent] 対象核酸の塩基配列を１細胞レベルで並列に検出する方法2020
- Inventor(s)
  大川　恭行、原田哲仁
- Industrial Property Rights Holder
  国立大学法人九州大学
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-18K19432
[Patent] 対象核酸の塩基配列を１細胞レベルで並列に検出する方法2020
- Inventor(s)
  大川　恭行、原田哲仁
- Industrial Property Rights Holder
  国立大学法人九州大学
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19H03211
[Patent] 対象核酸の塩基配列を１細胞レベルで並列に検出する方法2020
- Inventor(s)
  大川　恭行、原田哲仁
- Industrial Property Rights Holder
  国立大学法人九州大学
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PUBLICLY-19H05425
[Patent] DNA結合タンパク質の結合領域の近傍に所望のDNA断片を挿入する方法2017
- Inventor(s)
  大川恭行,,原田哲仁,胡桃坂仁志,木村宏,半田哲也,他2名
- Industrial Property Rights Holder
  大川恭行,,原田哲仁,胡桃坂仁志,木村宏,半田哲也,他2名
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Overseas
- Data Source
  KAKENHI-PUBLICLY-16H01219
[Patent] DNA結合タンパク質の結合領域の近傍に所望のDNA断片を挿入する方法2016
- Inventor(s)
  大川恭行,原田哲仁,胡桃坂仁志,木村宏,半田哲也,他2名
- Industrial Property Rights Holder
  国立大学法人九州大学、国立大学法人東京工業大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-167967
- Filing Date
  2016-08-30
- Data Source
  KAKENHI-PROJECT-15K18457
[Patent] DNA結合タンパク質の結合領域の近傍に所望のDNA断片を挿入する方法2016
- Inventor(s)
  大川恭行、原田哲仁、胡桃坂仁志、木村宏、半田哲也、他2名
- Industrial Property Rights Holder
  国立大学法人九州大学、国立大学法人東京工業大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-167967
- Filing Date
  2016-08-30
- Data Source
  KAKENHI-PUBLICLY-16H01219
[Presentation] High-throughput single cell multi-epigenomic profiling using chromatin integration labelling-sequence2023
- Author(s)
  Akihito Harada, Takeru Fujii, Kazumitsu Maehara, Yasuyuki Ohkawa
- Organizer
  Cell Symposia | The Conceptual Power of Single Cell Biology 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05292
[Presentation] 細胞状態のダイナミクスを解析する空間マルチオミクス技術の開発2023
- Author(s)
  原田哲仁、富松航佑
- Organizer
  第46回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-21H05292
[Presentation] 細胞状態のダイナミクスを解析する空間マルチオミクス技術の開発2023
- Author(s)
  原田哲仁、富松航佑
- Organizer
  第46回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27087
[Presentation] 細胞状態変化を計測するためのマルチオミクス技術開発2023
- Author(s)
  原田哲仁、富松航佑
- Organizer
  第16回日本エピジェネティクス研究会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27087
[Presentation] High-throughput single cell multi-epigenomic profiling using chromatin integration labelling-sequence2023
- Author(s)
  Akihito Harada, Takeru Fujii, Kazumitsu Maehara, Yasuyuki Ohkawa
- Organizer
  Cell Symposia | The Conceptual Power of Single Cell Biology 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27087
[Presentation] 単一細胞マルチエピゲノム解析による分化過程のクロマチンダイナミクスの可視化2023
- Author(s)
  原田哲仁、藤井健、前原一満、木村宏、大川恭行
- Organizer
  第46回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-21H05292
[Presentation] 細胞状態変化を計測するためのマルチオミクス技術開発2023
- Author(s)
  原田哲仁、富松航佑
- Organizer
  第16回日本エピジェネティクス研究会年会
- Invited
- Data Source
  KAKENHI-PLANNED-21H05292
[Presentation] 単一細胞マルチエピゲノム解析による分化過程のクロマチンダイナミクスの可視化2023
- Author(s)
  原田哲仁、藤井健、前原一満、木村宏、大川恭行
- Organizer
  第46回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27087
[Presentation] 単一細胞エピゲノム解析を用いたクロマチンマッピングによるゲノム機能の解明2022
- Author(s)
  原田哲仁, 藤井健, 前原一満, 木村宏, 大川恭行
- Organizer
  第45回分子生物学会
- Data Source
  KAKENHI-PLANNED-21H05292
[Presentation] 組織特異的な遺伝子発現機構の解明2022
- Author(s)
  原田哲仁
- Organizer
  筑波大学TARAセミナー
- Invited
- Data Source
  KAKENHI-PLANNED-21H05292
[Presentation] 単一細胞エピゲノム解析によるゲノム動作原理の理解2022
- Author(s)
  原田哲仁
- Organizer
  第15回日本エピジェネティクス研究会年会
- Data Source
  KAKENHI-PLANNED-21H05292
[Presentation] Epigenomic lineage tracing toward the understanding acquisition of tissue-specific gene expression profile2021
- Author(s)
  原田哲仁
- Organizer
  ＩＭＳセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19H03211
[Presentation] ChIL法による単一細胞マルチオミクスプロファイリング2021
- Author(s)
  原田哲仁, 藤井健, 前原一満, 田中かおり, 木村宏, 大川恭行
- Organizer
  第44回日本分子生物学会
- Data Source
  KAKENHI-PUBLICLY-21H00430
[Presentation] Epigenomic lineage tracing toward the understanding acquisition of tissue-specific gene expression profile2021
- Author(s)
  原田哲仁
- Organizer
  ＩＭＳセミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05368
[Presentation] ChIL法による単一細胞マルチオミクスプロファイリング2021
- Author(s)
  原田哲仁
- Organizer
  第44回日本分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03211
[Presentation] Epigenomic lineage tracing toward the understanding acquisition of tissue-specific gene expression profile2021
- Author(s)
  原田哲仁
- Organizer
  ＩＭＳセミナー
- Invited
- Data Source
  KAKENHI-PLANNED-21H05292
[Presentation] ChIL法による単一細胞マルチオミクスプロファイリング2021
- Author(s)
  原田哲仁, 藤井健, 前原一満, 田中かおり, 木村宏, 大川恭行
- Organizer
  第44回日本分子生物学会
- Data Source
  KAKENHI-PUBLICLY-20H05368
[Presentation] Epigenomic lineage tracing toward the understanding acquisition of tissue-specific gene expression profile.2021
- Author(s)
  原田哲仁
- Organizer
  ＩＭＳセミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00430
[Presentation] ChIL法による単一細胞マルチオミクスプロファイリング2021
- Author(s)
  原田哲仁
- Organizer
  第44回日本分子生物学会
- Invited
- Data Source
  KAKENHI-PLANNED-21H05292
[Presentation] 組織切片を用いたエピゲノム解析2020
- Author(s)
  原田哲仁, 前原一満, 田中かおり, 半田哲也, 木村宏, 大川恭行
- Organizer
  日本農芸化学会2020年度大会
- Data Source
  KAKENHI-PUBLICLY-19H05425
[Presentation] ChIL法による単一細胞エピゲノムプロファイリング.2020
- Author(s)
  原田哲仁, 前原一満, 半田哲也, 木村宏 , 大川恭行
- Organizer
  第43回日本分子生物学会
- Data Source
  KAKENHI-PUBLICLY-19H05425
[Presentation] 組織切片を用いたエピゲノム解析2020
- Author(s)
  原田哲仁, 前原一満, 田中かおり, 半田哲也, 木村宏, 大川恭行
- Organizer
  日本農芸化学会2020年度大会
- Data Source
  KAKENHI-PROJECT-19H03211
[Presentation] 組織切片を用いたエピゲノム解析2020
- Author(s)
  原田哲仁, 前原一満, 田中かおり, 半田哲也, 木村宏, 大川恭行
- Organizer
  日本農芸化学会2020年度大会
- Data Source
  KAKENHI-PROJECT-18K19432
[Presentation] ChIL法による単一細胞エピゲノムプロファイリング.2020
- Author(s)
  原田哲仁, 前原一満, 半田哲也, 木村宏 , 大川恭行
- Organizer
  第43回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19H03211
[Presentation] ChIL法による単一細胞エピゲノムプロファイリング.2020
- Author(s)
  原田哲仁, 前原一満, 半田哲也, 木村宏 , 大川恭行
- Organizer
  第43回日本分子生物学会
- Data Source
  KAKENHI-PUBLICLY-20H05368
[Presentation] ヒストンH3バリアントの選択的取り込みによる組織特異的な遺伝子発現制御2019
- Author(s)
  原田哲仁, 小松哲郎, 前原一満, 近藤友佳理, 田中かおり, 桑門温子, 佐藤優子, 木村宏, 林克彦, 小野悠介, 竹本龍也, 胡桃坂仁志, 大川恭行
- Organizer
  第47回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19H03211
[Presentation] ヒストンH3バリアントの選択的取り込みによる組織特異的な遺伝子発現制御2019
- Author(s)
  原田哲仁, 小松哲郎, 前原一満, 近藤友佳理, 田中かおり, 桑門温子, 佐藤優子, 木村宏, 林克彦, 小野悠介, 竹本龍也, 胡桃坂仁志, 大川恭行
- Organizer
  第47回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K19432
[Presentation] High-throughput single cell epigenomic profiling using chromatin integration labelling-sequence2019
- Author(s)
  Akihito Harada, Kazumitsu Maehara, Yasuyuki Ohkawa
- Organizer
  Keystone Symposia on Molecular and Cellular Biology Epigenetics and Human Disease/3D Genome: Gene Regulation and Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19432
[Presentation] ヒストンH3バリアントの選択的取り込みによる組織特異的な遺伝子発現制御2019
- Author(s)
  原田哲仁, 小松哲郎, 前原一満, 近藤友佳理, 田中かおり, 桑門温子, 佐藤優子, 木村宏, 林克彦, 小野悠介, 竹本龍也, 胡桃坂仁志, 大川恭行
- Organizer
  第47回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-19H05425
[Presentation] Functional switching of histone H3 variants in myogenesis2017
- Author(s)
  原田哲仁
- Organizer
  第4回ヒストンバリアント研究会
- Place of Presentation
  東北大学青葉山新キャンパス　青葉山コモンズ
- Invited
- Data Source
  KAKENHI-PROJECT-15K18457
[Presentation] 急性期の筋萎縮過程における遺伝子発現変動解析2017
- Author(s)
  原田哲仁，岩崎健，横田和也，岡田誠司，大川恭行
- Organizer
  日本農芸化学会2017年度大会
- Place of Presentation
  京都女子大（京都府）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PUBLICLY-16H01219
[Presentation] トランスクリプトミクス研究における新しい展開2017
- Author(s)
  原田哲仁
- Organizer
  タカラバイオ主催TGCAセミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01219
[Presentation] 生殖細胞におけるヒストンバリアントによるゲノムマーキング機構の解明2017
- Author(s)
  原田哲仁
- Organizer
  生殖細胞のエピゲノムダイナミクスとその制御第5回公開シンポジウム
- Data Source
  KAKENHI-PUBLICLY-16H01219
[Presentation] Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration2017
- Author(s)
  原田哲仁
- Organizer
  1st Munchen-Japan Mini Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01219
[Presentation] エピジェネティック破綻により引き起こされた筋肉腫の解析2017
- Author(s)
  原田哲仁
- Organizer
  公益財団法人福岡県すこやか健康事業団平成28年度がん研究助成金優秀賞受賞講演
- Place of Presentation
  西鉄グランドホテル（福岡県福岡市）
- Invited
- Data Source
  KAKENHI-PROJECT-15K18457
[Presentation] 非免疫沈降法ChILT法による少数細胞のエピゲノム解析2017
- Author(s)
  原田哲仁、半田哲也、野上順平、有村泰宏、関根慧、中尾勝、藤田理紗、前原一満、胡桃坂仁志、木村宏、大川恭行
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PUBLICLY-16H01219
[Presentation] Functional switching of histone H3 variants in myogenesis2017
- Author(s)
  原田哲仁
- Organizer
  第4回ヒストンバリアント研究会
- Place of Presentation
  東北大学青葉山新キャンパス　青葉山コモンズ
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01219
[Presentation] エピジェネティック破綻により引き起こされた筋肉腫の解析2017
- Author(s)
  原田哲仁
- Organizer
  公益財団法人福岡県すこやか健康事業団平成28年度がん研究助成金優秀賞受賞講演
- Place of Presentation
  西鉄グランドホテル（福岡県福岡市）
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01219
[Presentation] ChILT：Immunoprecipitation-Free Epigenome Profiling Technology2017
- Author(s)
  原田哲仁
- Organizer
  3領域合同若手勉強会2017
- Data Source
  KAKENHI-PUBLICLY-16H01219
[Presentation] 急性期の筋萎縮過程における遺伝子発現変動解析2017
- Author(s)
  原田哲仁，岩崎健，横田和也，岡田誠司，大川恭行
- Organizer
  日本農芸化学会2017年度大会
- Place of Presentation
  京都女子大（京都府）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15K18457
[Presentation] Functional analysis of novel histone variant H3mm13 in skeletal muscle to Histone variants2017
- Author(s)
  原田哲仁
- Organizer
  EMBO Workshop Histone Vriants
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01219
[Presentation] ヒストンH3バリアントの発現変動は筋萎縮過程の初期イベントである2016
- Author(s)
  原田哲仁, 岩崎健, 横田和也, 岡田誠司, 大川恭行
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PUBLICLY-16H01219
[Presentation] ヒストンH3バリアントの発現変動は筋萎縮過程の初期イベントである2016
- Author(s)
  原田哲仁, 岩崎健, 横田和也, 岡田誠司, 大川恭行
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K18457
[Presentation] 新規ヒストンH3バリアントH3mm7は骨格筋分化能を制御する2016
- Author(s)
  原田哲仁
- Organizer
  日本農芸化学会 2016 大会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-15K18457
[Presentation] 骨格筋分化におけるクロマチン構造解析-トランスクリプトミクスで理解する骨格筋形成2016
- Author(s)
  原田哲仁
- Organizer
  日本農芸化学会中四国支部支部創立15周年記念第24回若手シンポジウム
- Place of Presentation
  水産大学校　(山口県下関市)
- Year and Date
  2016-07-28
- Invited
- Data Source
  KAKENHI-PROJECT-15K18457
[Presentation] 骨格筋分化におけるクロマチン構造解析-トランスクリプトミクスで理解する骨格筋形成2016
- Author(s)
  原田哲仁
- Organizer
  日本農芸化学会中四国支部支部創立15周年記念第24回若手シンポジウム
- Place of Presentation
  水産大学校　(山口県下関市)
- Year and Date
  2016-07-28
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01219
[Presentation] ヒストンバリアントが制御する骨格筋分化能2015
- Author(s)
  原田哲仁、前原一満、大川恭行
- Organizer
  NGS現場の会第四回研究会
- Place of Presentation
  つくば国際会議場
- Year and Date
  2015-07-01
- Invited
- Data Source
  KAKENHI-PROJECT-15K18457
[Presentation] 新規ヒストンH3バリアントH3mm7は骨格筋分化能を制御する2015
- Author(s)
  原田哲仁
- Organizer
  第38回日本分子生物学年会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K18457

1. Koji Shiraishi (00535255)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 大川恭行 (80448430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
3. 井垣達吏 (00467648)

# of Collaborated Projects: 1 results

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4. 佐々木洋 (10211939)

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5. 戸田聡 (20738835)

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6. 石谷太 (40448428)

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7. 藤田恭之 (50580974)

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8. 西村栄美 (70396331)

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9. 小田裕香子 (70452498)

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# of Collaborated Products: 1 results
10. 平島剛志 (10620198)

# of Collaborated Projects: 1 results

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11. ITO YUMA

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# of Collaborated Products: 2 results
12. OKADA Yuki

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# of Collaborated Products: 1 results
13. OKADA Seiji

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# of Collaborated Products: 1 results
14. TAMURA Kentaro

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15. 臼井将勝

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16. 阿座上弘行

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# of Collaborated Products: 1 results
17. 落合博

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18. 木村宏

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# of Collaborated Products: 2 results
19. 前原一満

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# of Collaborated Products: 1 results
20. 北嶋康雄

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21. 木村龍一

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22. 大石裕晃

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23. 和泉自泰

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24. 長尾恒治

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25. 富松航佑

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26. 赤司浩一

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27. 小布施力史

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28. 深田宗一朗

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Harada Akihito 原田 哲仁

HARADA AKIHITO 原田 哲仁

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精子形成における体細胞型H3から精子型H3T/tへのヒストン置換の意義の解明Principal Investigator

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無精子症における精巣内内分泌環境に着目した単一細胞トランスクリプトーム解析

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位置情報を保持したシンギュラリティ細胞の遺伝子発現測定技術の開発Principal Investigator

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[Book] Precision Medicine2023

Author(s)

Total Pages

Harada Akihito 原田哲仁

HARADA AKIHITO 原田哲仁