Ishii Sumiyasu 石井角保

… Alternative Names

Sumiyasu Ishii 石井角保

石井角保イシイスミヤス

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Researcher Number	60638112
Other IDs
Affiliation (Current)	2026: 新潟県立看護大学, 看護学部, 教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 新潟県立看護大学, 看護学部, 教授 2021 – 2022: 群馬大学, 大学院医学系研究科, 講師 2015 – 2017: 群馬大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 54040:Metabolism and endocrinology-related Except Principal Investigator Endocrinology
Keywords	Principal Investigator HDAC3 / 甲状腺ホルモン不応症 / 甲状腺 / 小脳 / 甲状腺ホルモン Except Principal Investigator 心脳血管障害誘発因子 / モデル動物 / アルドステロン産生腫瘍 / 副腎 / ＫＣＮＪ５ … More / KCNJ5変異 / 腫瘍発生 / 高血圧症 / 原発性アルドステロン症 Less

HDAC3によるゲノム三次元区画化制御に着目した甲状腺ホルモン不応症の病態解明Principal Investigator
- Principal Investigator
  
  石井角保
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Niigata College of Nursing
Functional analysis of HDAC3 in hypothyroidism and study of genome compartmentalization by a new method.Principal Investigator
- Principal Investigator
  
  Sumiyasu Ishii
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Niigata College of Nursing
  Gunma University
Insight into mechanisims undelying Primary aldosteronism
- Principal Investigator
  
  Masanobu Yamada
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Endocrinology
- Research Institution
  Gunma University

All 2024 2023 2022 2021 2017 2016

All Journal Article Presentation

[Journal Article] VI. Resistance to Thyroid Hormone: Diagnosis and Treatment2024
- Author(s)
  Ishii Sumiyasu
- Journal Title
  
  Nihon Naika Gakkai Zasshi
  
  Volume: 113 Issue: 4 Pages: 648-653
- DOI
  10.2169/naika.113.648
- ISSN
  0021-5384, 1883-2083
- Year and Date
  2024-04-10
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-24K11682
[Journal Article] 17β-Estradiol (E2) Activates Matrix Mineralization through Genomic/Nongenomic Pathways in MC3T3-E1 Cells2024
- Author(s)
  Suzuki Hiraku、Fujiwara Yuki、Ariyani Winda、Amano Izuki、Ishii Sumiyasu、Ninomiya Ayane Kate、Sato Seiichi、Takaoka Akinori、Koibuchi Noriyuki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 9 Pages: 4727-4727
- DOI
  10.3390/ijms25094727
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K17266, KAKENHI-PROJECT-24K11682
[Journal Article] Online Physiology Practice with Team-Based Learning During the COVID-19 Pandemic2023
- Author(s)
  Fujiwara Yuki、Amano Izuki、Ishii Sumiyasu、Kishi Mikiko、Koibuchi Noriyuki
- Journal Title
  
  Advances in Medical Education and Practice
  
  Volume: Volume 14 Pages: 1435-1443
- DOI
  10.2147/amep.s415257
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08569, KAKENHI-PROJECT-21K17266
[Journal Article] 甲状腺ホルモン不応症の診断と治療2022
- Author(s)
  石井角保
- Journal Title
  
  Medical Practice
  
  Volume: 39 Pages: 61-65
- Data Source
  KAKENHI-PROJECT-21K08569
[Journal Article] The neurotoxic effect of lactational PFOS exposure on cerebellar functional development in male mice2022
- Author(s)
  Ninomiya A, Mshaty A, Haijima A, Yajima H, Kokubo M, Khairinisa MA, Ariyani W, Fujiwara Y, Ishii S, Hosoi N, Hirai H, Amano I, Koibuchi N.
- Journal Title
  
  Food Chem Toxicol
  
  Volume: 159:112751 Pages: 112751-112751
- DOI
  10.1016/j.fct.2021.112751
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07103, KAKENHI-PROJECT-18H03379, KAKENHI-PROJECT-20K06906, KAKENHI-PROJECT-21K08569, KAKENHI-PROJECT-21K17266, KAKENHI-PROJECT-22KJ0445
[Journal Article] Long-term depression?inductive stimulation causes long-term potentiation in mouse Purkinje cells with a mutant thyroid hormone receptor2022
- Author(s)
  Ninomiya Ayane、Amano Izuki、Kokubo Michifumi、Takatsuru Yusuke、Ishii Sumiyasu、Hirai Hirokazu、Hosoi Nobutake、Koibuchi Noriyuki
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 119 Issue: 45
- DOI
  10.1073/pnas.2210645119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06906, KAKENHI-PROJECT-21K08569
[Journal Article] Histone Deacetylase 3 Inhibitor Alleviates Cerebellar Defects in Perinatal Hypothyroid Mice by Stimulating Histone Acetylation and Transcription at Thyroid Hormone-Responsive Gene Loci2022
- Author(s)
  Susetyo Alvin、Ishii Sumiyasu、Fujiwara Yuki、Amano Izuki、Koibuchi Noriyuki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 14 Pages: 7869-7869
- DOI
  10.3390/ijms23147869
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08569
[Journal Article] COUP-TFII in Kidneys, from Embryos to Sick Adults2022
- Author(s)
  Ishii Sumiyasu、Koibuchi Noriyuki
- Journal Title
  
  Diagnostics
  
  Volume: 12 Issue: 5 Pages: 1181-1181
- DOI
  10.3390/diagnostics12051181
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08569
[Journal Article] The Role of Thyroid Hormone in the Regulation of Cerebellar Development2021
- Author(s)
  Ishii Sumiyasu、Amano Izuki、Koibuchi Noriyuki
- Journal Title
  
  Endocrinology and Metabolism
  
  Volume: 36 Issue: 4 Pages: 703-716
- DOI
  10.3803/enm.2021.1150
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16486, KAKENHI-PROJECT-18H03379, KAKENHI-PROJECT-21K08569, KAKENHI-PROJECT-21K15340
[Journal Article] The Role of Histone Deacetylase 3 Complex in Nuclear Hormone Receptor Action2021
- Author(s)
  Ishii Sumiyasu
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 17 Pages: 9138-9138
- DOI
  10.3390/ijms22179138
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08569
[Journal Article] Characteristics of Japanese aldosterone-producing adenomas with KCNJ5 mutations.2017
- Author(s)
  Okamura T, Nakajima Y, Katano-Toki A, Horiguchi K, Matsumoto S, Yoshino S, Yamada E, Tomaru T, Ishii S, Saito T, Ozawa A, Shibusawa N, Satoh T, Okada S, Nagaoka R, Takada D, Horiguchi J, Oyama T, Yamada M.
- Journal Title
  
  Endocr J.
  
  Volume: 64 Pages: 39-47
- NAID
  130005305975
- Data Source
  KAKENHI-PROJECT-15H04852
[Journal Article] GNAS mutations in adrenal aldosterone-producing adenomas2016
- Author(s)
  Nakajima Y, Okamura T, Horiguchi K, Gohko T, Miyamoto T, Satoh T, Ozawa A, Ishii S, Yamada E, Hashimoto K, Okada S, Takata D, Horiguchi J, Yamada M.
- Journal Title
  
  Endocr J.
  
  Volume: 63 Pages: 199-204
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04852
[Journal Article] GNAS mutations in adrenal aldosterone-producing adenomas [Rapid Communication]2016
- Author(s)
  Nakajima Y, Okamura T, Horiguchi K, Gohko T, Miyamoto T, Satoh T, Ozawa A, Ishii S, Yamada E, Hashimoto K, Okada S, Takata D, Horiguchi J, Yamada M.
- Journal Title
  
  Endocr J
  
  Volume: 63 Issue: 2 Pages: 199-204
- DOI
  10.1507/endocrj.EJ15-0642
- NAID
  130005127192
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09242, KAKENHI-PROJECT-26461353, KAKENHI-PROJECT-15H04852
[Presentation] 2024年度の指定難病制度の動向と甲状腺ホルモン不応症2024
- Author(s)
  石井角保
- Organizer
  第67回日本甲状腺学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-24K11682
[Presentation] 甲状腺ホルモン不応症診療の注意点2024
- Author(s)
  石井角保、堀口和彦
- Organizer
  第34回臨床内分泌代謝 Update
- Invited
- Data Source
  KAKENHI-PROJECT-24K11682
[Presentation] 「甲状腺ホルモン不応症の手引き」の刊行2023
- Author(s)
  石井角保、山田正信
- Organizer
  第66回日本甲状腺学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K08569
[Presentation] 変異甲状腺ホルモン受容体を発現させたマウスプルキンエ細胞では、長期抑圧誘発刺激は長期増強を惹起する2023
- Author(s)
  二ノ宮彩音、天野出月、小久保倫文、高鶴裕介、石井角保、平井宏和、細井延武、鯉淵典之
- Organizer
  第96回日本内分泌学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08569
[Presentation] The indispensable role of thyroid hormone during development in the maintenance of cerebellar function in adulthood2023
- Author(s)
  Ayane Ninomiya, Izuki Amano, Michifumi Kokubo, Yusuke Takatsuru, Sumiyasu Ishii, Hirokazu Hirai, Nobutake Hosoi, Noriyuki Koibuchi
- Organizer
  第66回日本甲状腺学会学術集会　国際分子甲状腺シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08569
[Presentation] 甲状腺ホルモン不応症とTSH産生PitNET2023
- Author(s)
  山田正信、堀口和彦、石井角保
- Organizer
  第33回臨床内分泌代謝Update
- Invited
- Data Source
  KAKENHI-PROJECT-21K08569
[Presentation] 甲状腺ホルモン不応症診療の手引きの作成2022
- Author(s)
  石井角保、山田正信
- Organizer
  第65回日本甲状腺学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-21K08569
[Presentation] ヒストン脱アセチル化酵素３阻害剤による周産期甲状腺機能低下症マウスの治療研究2022
- Author(s)
  石井角保、Alvin Susetyo、天野出月、鯉淵典之
- Organizer
  第95回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08569
[Presentation] Histone deacetylase 3 inhibition mitigates hypothyroidism-induced cerebellar developmental defects in mice2022
- Author(s)
  Alvin Susetyo, Sumiyasu Ishii, Izuki Amano, Noriyuki Koibuchi
- Organizer
  第99回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-21K08569
[Presentation] ヒストン脱アセチル化酵素3阻害剤は生体内で標的遺伝子のヒストンをアセチル化し甲状腺機能低下症による小脳発達障害を軽減する2022
- Author(s)
  石井角保、Alvin Susetyo、天野出月、鯉淵典之
- Organizer
  第65回日本甲状腺学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08569
[Presentation] Functional analysis of a lncRNA THRB-AS22022
- Author(s)
  石井角保、鯉淵典之
- Organizer
  第99回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-21K08569
[Presentation] 臨床重要課題　甲状腺ホルモン不応症の診断基準ならびに治療指針の作成2021
- Author(s)
  石井角保、山田正信
- Organizer
  第64回日本甲状腺学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-21K08569
[Presentation] ベータ型甲状腺ホルモン受容体遺伝子逆鎖由来long non-coding RNAのTHP-1細胞における機能解析2021
- Author(s)
  石井角保、堀口和彦、中島康代、小澤厚志、渋沢信行、佐藤哲郎、天野出月、宮崎航、山田正信、鯉淵典之
- Organizer
  第94回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08569
[Presentation] The role of histone deacetylase 3 (HDAC3) in cerebellar developmental defects induced by hypothyroidism2021
- Author(s)
  Alvin Susetyo, Sumiyasu Ishii, Izuki Amano, Noriyuki Koibuchi
- Organizer
  第94回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08569
[Presentation] ヒストン脱アセチル化酵素３阻害剤投与により周産期甲状腺機能低下症マウスの運動協調障害が軽減される2021
- Author(s)
  石井角保、Alvin Susetyo、天野出月、鯉淵典之
- Organizer
  第64回日本甲状腺学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08569
[Presentation] The role of histone deacetylase 3 in motor coordination defects induced by perinatal hypothyroidism2021
- Author(s)
  Alvin Susetyo, Sumiyasu Ishii, Izuki Amano, Noriyuki Koibuchi
- Organizer
  11th International Symposium of the Society for Research on the Cerebellum and Ataxias
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08569
[Presentation] アジアのアルドステロン産生腺腫の特徴2017
- Author(s)
  吉岡誠之, 中島康代, 岡村孝志, 石田恵美, 土岐明子, 吉野聡, 堀口和彦, 石井角保, 小澤厚志, 渋沢信行, 佐藤哲郎, 山田正信
- Organizer
  第18回日本内分泌学会関東甲信越支部学術集会
- Data Source
  KAKENHI-PROJECT-15H04852
[Presentation] アジアのKCNJ5変異陽性アルドステロン産生腺腫は欧米と異なる特徴を示す2017
- Author(s)
  中島康代(群馬大学大学院医学系研究科病態制御内科学), 岡村孝志, 土岐明子, 吉野聡, 堀口和彦, 松本俊一, 登丸琢也, 石井角保, 小澤厚志, 渋沢信行, 佐藤哲郎, 山田正信
- Organizer
  第９０回日本内分泌学会学術集会
- Data Source
  KAKENHI-PROJECT-15H04852

1. Masanobu Yamada (90261833)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. 小澤厚志 (10573496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. 堀口和彦 (10737943)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. 佐藤哲郎 (40302484)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. 桑原正靖 (40334130)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 中島康代 (70707017)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. 渋沢信行 (90396622)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. 鯉淵典之 (80234681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. HOSOI Nobutake

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 天野出月

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 藤原悠基

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ishii Sumiyasu 石井 角保

Sumiyasu Ishii 石井 角保

石井 角保 イシイ スミヤス

Research Projects

Research Products

Co-Researchers

HDAC3によるゲノム三次元区画化制御に着目した甲状腺ホルモン不応症の病態解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of HDAC3 in hypothyroidism and study of genome compartmentalization by a new method.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Insight into mechanisims undelying Primary aldosteronism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] VI. Resistance to Thyroid Hormone: Diagnosis and Treatment2024

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] 17β-Estradiol (E2) Activates Matrix Mineralization through Genomic/Nongenomic Pathways in MC3T3-E1 Cells2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Online Physiology Practice with Team-Based Learning During the COVID-19 Pandemic2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 甲状腺ホルモン不応症の診断と治療2022

Author(s)

Journal Title

Data Source

[Journal Article] The neurotoxic effect of lactational PFOS exposure on cerebellar functional development in male mice2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Long-term depression?inductive stimulation causes long-term potentiation in mouse Purkinje cells with a mutant thyroid hormone receptor2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Histone Deacetylase 3 Inhibitor Alleviates Cerebellar Defects in Perinatal Hypothyroid Mice by Stimulating Histone Acetylation and Transcription at Thyroid Hormone-Responsive Gene Loci2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] COUP-TFII in Kidneys, from Embryos to Sick Adults2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Role of Thyroid Hormone in the Regulation of Cerebellar Development2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Role of Histone Deacetylase 3 Complex in Nuclear Hormone Receptor Action2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characteristics of Japanese aldosterone-producing adenomas with KCNJ5 mutations.2017

Author(s)

Journal Title

NAID

Ishii Sumiyasu 石井角保

Sumiyasu Ishii 石井角保

石井角保イシイスミヤス

[Presentation] 臨床重要課題　甲状腺ホルモン不応症の診断基準ならびに治療指針の作成2021