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ARIMA YUICHIRO  有馬 勇一郎

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ARIMA Yuichiro  有馬 勇一郎

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Researcher Number 60706414
Other IDs
Affiliation (Current) 2025: 熊本大学, 国際先端医学研究機構, 特任准教授
Affiliation (based on the past Project Information) *help 2021 – 2025: 熊本大学, 国際先端医学研究機構, 特任准教授
2018 – 2020: 熊本大学, 大学院生命科学研究部(医), 助教
2017: 熊本大学, 医学部生命科学研究部, 助教
2017: 熊本大学, 医学部附属病院, 特任助教
2016: 熊本大学, 医学部附属病院, 寄附講座教員
2015: 国立研究開発法人国立循環器病研究センター, 研究所, 研究員
2013 – 2014: 熊本大学, 医学部附属病院, 助教
Review Section/Research Field
Principal Investigator
Cardiovascular medicine / Basic Section 53020:Cardiology-related / Medium-sized Section 53:Organ-based internal medicine and related fields / Basic Section 52050:Embryonic medicine and pediatrics-related
Except Principal Investigator
Basic Section 53020:Cardiology-related / Basic Section 56060:Ophthalmology-related / Basic Section 09030:Childhood and nursery/pre-school education-related / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Cardiovascular medicine
Keywords
Principal Investigator
ケトン体代謝 / DOHaD / Hmgcs2 / ケトン体 / エピゲノム / アセチル化 / ミトコンドリア / 心不全 / 新生児期 / 心筋成熟 … More / 低出生体重児 / 出生時低体重 / HDAC / DNAメチル化 / ヒストン修飾 / 出生児低体重 / 異所性脂肪沈着 / 動物モデル / 低出生体重 / 発生 / 比較解剖 / 冠循環 / 冠動脈 / 側副血行路 … More
Except Principal Investigator
心アミロイドーシス / 心不全パンデミック / トランスサイレチン型心アミロイドーシス / サルコペニア / 心不全 / 骨格筋 / マイクロRNA / 循環障害 / 炎症 / 網膜循環障害 / ミトコンドリア / 網羅的解析 / 生体イメージング / 緑内障 / 養育環境 / ストレス耐性 / エピゲノム / 脳機能 / レジリエンス / 冠微小循環 / パチシラン / タファミジス / メタボロミクス / 心筋生検 / 冠微小循環障害 / 心内微小環境 / ネフロン前駆細胞 / Flcn / 栄養感知機構 / 栄養状態 / 胎生期 / 腎発生 / 循環器 / アルデヒド脱水素酵素2 / インターロイキン / ヘリコバクター・ピロリ / 遺伝子多型 / 遺伝要因 / 環境要因 / 急性心筋梗塞 / ヘリコバクター・ピロリ感染 / 動脈硬化 Less
  • Research Projects

    (14 results)
  • Research Products

    (25 results)
  • Co-Researchers

    (20 People)
  •  Elucidation of the circulatory regulatory mechanisms mediated by the non-energy substrate functions of ketone bodies.Principal Investigator

    • Principal Investigator
      有馬 勇一郎
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Kumamoto University
  •  Investigation of the cardioprotective effect of skeletal muscle-derived microRNAs in vivo

    • Principal Investigator
      泉家 康宏
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Kumamoto University
  •  個別化医療実現に向けた心アミロイドーシス病態フェノタイピングの試み

    • Principal Investigator
      辻田 賢一
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Kumamoto University
  •  Unraveling the Brain Structure, Function, and Epigenomic Vulnerability of Psychological Resilience.

    • Principal Investigator
      西川 里織
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 09030:Childhood and nursery/pre-school education-related
    • Research Institution
      Kumamoto University
  •  ケトン体代謝によるエピゲノム制御作用を介した循環器疾患形成機序の解明Principal Investigator

    • Principal Investigator
      有馬 勇一郎
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Fund for the Promotion of Joint International Research (International Collaborative Research)
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      Kumamoto University
  •  生体イメージングと網羅的解析によるミトコンドリア面からみた緑内障とその治療法探索

    • Principal Investigator
      瀧原 祐史
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Kumamoto University
  •  心内微小環境に着目したトランスサイレチン型心アミロイドーシス病態解明

    • Principal Investigator
      辻田 賢一
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Kumamoto University
  •  新生児期のケトン体代謝を介した心筋成熟・心内微小環境構築機序の解明Principal Investigator

    • Principal Investigator
      有馬 勇一郎
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Kumamoto University
  •  Elucidation of the mechanisms of healthy kidney formation via nutrient sensing signals during the fetal period

    • Principal Investigator
      Baba Masaya
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
    • Research Institution
      Kumamoto University
  •  Elucidation of the mechanism of increased risk of adult onset cardiovascular disease in low birth weight infants focusing on DNA methylationPrincipal Investigator

    • Principal Investigator
      Arima Yuichiro
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Kumamoto University
  •  Cardiovascular adaptation mechanisms in murine low birth weight modelPrincipal Investigator

    • Principal Investigator
      Arima Yuichiro
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Kumamoto University
  •  Analysis of onset, progression, and recurrence of acute myocardial infarction from the view of genetic and environmental factors

    • Principal Investigator
      Hokimoto Seiji
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Kyushu University of Nursing and Social Welfare
      Kumamoto University
  •  Development of the murine low birth weight modelPrincipal Investigator

    • Principal Investigator
      Arima Yuichiro
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Kumamoto University
      National Cardiovascular Center Research Institute
  •  Basic research for the collaterogenesis in coronary circulationPrincipal Investigator

    • Principal Investigator
      ARIMA Yuichiro
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Kumamoto University

All 2023 2022 2021 2020 2019 2018 2016 2014 Other

All Journal Article Presentation

  • [Journal Article] East Asian variant aldehyde dehydrogenase type 2 genotype exacerbates ischemia/reperfusion injury with ST-elevation myocardial infarction in men: possible sex differences2022

    • Author(s)
      Ishida T, Arima Y, Mizuno Y, Harada E, Yamashita T, Sueta D, Sakamoto K, Suzuki S, Kaikita K, Yamada Y, Shimomura H, Oniki K, Saruwatari J, Hokimoto S, Yasue H, Tsujita K.
    • Journal Title

      Heart and Vessels

      Volume: 37 Issue: 2 Pages: 184-193

    • DOI

      10.1007/s00380-021-01907-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07166, KAKENHI-PROJECT-19K08520, KAKENHI-PROJECT-18K08110, KAKENHI-PROJECT-20K07134
  • [Journal Article] Impact of cerebrovascular comorbidity on prognosis in Japanese patients undergoing PCI: 1-year data from Japanese multicenter registry (KICS).2022

    • Author(s)
      Ahmed K., Arima Y., et. al.
    • Journal Title

      Heart and Vessels

      Volume: in press Issue: 6 Pages: 911-918

    • DOI

      10.1007/s00380-021-01997-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08520
  • [Journal Article] Murine neonatal ketogenesis preserves mitochondrial energetics by preventing protein hyperacetylation2021

    • Author(s)
      Arima Yuichiro、Nakagawa Yoshiko、Takeo Toru、Ishida Toshifumi、Yamada Toshihiro、et al.
    • Journal Title

      Nature Metabolism

      Volume: 3 Issue: 2 Pages: 196-210

    • DOI

      10.1038/s42255-021-00342-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08110, KAKENHI-PROJECT-19K08520, KAKENHI-PROJECT-19H03711, KAKENHI-PROJECT-20H04108, KAKENHI-PROJECT-18K06817, KAKENHI-PROJECT-19K22639, KAKENHI-PROJECT-19K16111, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K09008, KAKENHI-PROJECT-19K17403, KAKENHI-PROJECT-19H04446, KAKENHI-PROJECT-21H02686, KAKENHI-PROJECT-21K07904, KAKENHI-PROJECT-21K19519, KAKENHI-PROJECT-20KK0185, KAKENHI-PROJECT-18H02798, KAKENHI-PROJECT-19H01048
  • [Journal Article] Developmental origins of health and disease theory in cardiology2020

    • Author(s)
      Arima Yuichiro、Fukuoka Hideoki
    • Journal Title

      Journal of Cardiology

      Volume: 20 Issue: 1 Pages: 1-4

    • DOI

      10.1016/j.jjcc.2020.02.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08520
  • [Journal Article] Fetal Origins of Hypertension2018

    • Author(s)
      Arima Y, Nishiyama K, Izumiya Y, Kaikita K, Hokimoto S, Tsujita K.
    • Journal Title

      Adv Exp Med Biol

      Volume: 1012 Pages: 41-48

    • DOI

      10.1007/978-981-10-5526-3_5

    • ISBN
      9789811055256, 9789811055263
    • Data Source
      KAKENHI-PROJECT-17K16014
  • [Journal Article] Evaluation of Collateral Source Characteristics With 3‐Dimensional Analysis Using Micro?X‐Ray Computed Tomography2018

    • Author(s)
      Arima Yuichiro、Hokimoto Seiji、Tabata Noriaki、Nakagawa Osamu、Oshima Asahi、Matsumoto Yosuke、Sato Takahiro、Mukunoki Toshifumi、Otani Jun、Ishii Masanobu、Uchikawa Michie、Yamamoto Eiichiro、Izumiya Yasuhiro、Kaikita Koichi、Ogawa Hisao、Nishiyama Koichi、Tsujita Kenichi
    • Journal Title

      Journal of the American Heart Association

      Volume: 7 Issue: 6

    • DOI

      10.1161/jaha.117.007800

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K16014, KAKENHI-PROJECT-15H04883, KAKENHI-PROJECT-16KT0173
  • [Journal Article] Helicobacter pylori Seropositivity in Patients with Interleukin-1 Polymorphisms Is Significantly Associated with ST-Segment Elevation Myocardial Infarction.2016

    • Author(s)
      Tabata N, Sueta D, Akasaka T, Arima Y, Sakamoto K, Yamamoto E, Izumiya Y, Yamamuro M, Tsujita K, Kojima S, Kaikita K, Morita K, Oniki K, Saruwatari J, Nakagawa K, Hokimoto S.
    • Journal Title

      PLoS One.

      Volume: 11 Issue: 11 Pages: e0166240-e0166240

    • DOI

      10.1371/journal.pone.0166240

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26360049, KAKENHI-PROJECT-15K18925, KAKENHI-PROJECT-16K08406, KAKENHI-PROJECT-16K09446
  • [Journal Article] Helicobacter Pylori-seropositivity along with genetic and environmental factors predicts clinical outcome after acute coronary syndrome.2016

    • Author(s)
      Tabata N, Hokimoto S, Akasaka T, Sueta D, Arima Y, Sakamoto K, Yamamoto E, Izumiya Y, Yamamuro M, Tsujita K, Kojima S, Kaikita K, Morita K, Oniki K, Saruwatari J, Nakagawa K, Ogawa H.
    • Journal Title

      Int J Cardiol.

      Volume: 212 Pages: 54-56

    • DOI

      10.1016/j.ijcard.2016.03.034

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26360049, KAKENHI-PROJECT-25860117, KAKENHI-PROJECT-15K18925, KAKENHI-PROJECT-16K09446
  • [Journal Article] Helicobacter pylori-seropositivity along with pro-inflammatory interleukin-1 polymorphisms correlated with myocardial infarction2016

    • Author(s)
      Noriaki Tabata, Seiji Hokimoto*, Tomonori Akasaka, Daisuke Sueta, Yuichiro Arima, Kenji Sakamoto, Eiichiro Yamamoto, Yasuhiro Izumiya, Megumi Yamamuro, Kenichi Tsujita, Sunao Kojima, Koichi Kaikita, Kazunori Morita, Kentaro Oniki, Junji Saruwatari, Kazuko Nakagawa, Hiroshige Yamabe, Kunihiko Matsui, Hisao Ogawa
    • Journal Title

      Clinical Trials and Regulatory Science in Cardiology

      Volume: 17 Pages: 9-14

    • DOI

      10.1016/j.ctrsc.2016.03.002

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09446
  • [Journal Article] Prolonged hyponatremia due to hypopituitarism in a patient with non-ST-elevation myocardial infarction2014

    • Author(s)
      Kyohei Marume, Yuichiro Arima, Motoyuki Igata, Takeshi Nishikawa, Eiichiro Yamamoto, Megumi Yamamuro, Kenichi Tsujita, Tomoko Tanaka, Koichi Kaikita, Seiji Hokimoto, Hisao Ogawa
    • Journal Title

      Journal of Cardiology Cases

      Volume: 10 Pages: 226-230

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25893187
  • [Journal Article] Comparison of the effect of CYP2C19 polymorphism on clinical outcome between acute coronary syndrome and stable angina2014

    • Author(s)
      Yuichiro Arima, Seiji Hokimoto, Tomonori Akasaka, Koichi Mizobe, Koichi Kaikita, Kentaro Oniki, Kazuko Nakagawa, Hisao Ogawa
    • Journal Title

      Journal of cardiology

      Volume: 14 Issue: 6 Pages: 221-224

    • DOI

      10.1016/j.jjcc.2014.07.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25893187, KAKENHI-PROJECT-26360049
  • [Presentation] Ketone Bodies as a Modulator of Metabolic Phenotype2023

    • Author(s)
      有馬勇一郎
    • Organizer
      第86回日本循環器学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K24305
  • [Presentation] ケトン体が結ぶ心腎連関機構の解明2022

    • Author(s)
      有馬勇一郎
    • Organizer
      第70回日本心臓病学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K24305
  • [Presentation] Ketone Body Metabolism and Blood Vessel Development2022

    • Author(s)
      Yuichiro Arima
    • Organizer
      2022 Annual Meeting of the Korean Society for Vascular Biology and Medicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24305
  • [Presentation] ケトン体に注目した心筋のエネルギー代謝2022

    • Author(s)
      有馬勇一郎
    • Organizer
      第26回日本心不全学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K24305
  • [Presentation] Morphogenesis of blood vessels.2021

    • Author(s)
      Yuichiro Arima
    • Organizer
      “ASIA-AUSTRALIA VASCULAR BIOLOGY MEETING 2022”
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08520
  • [Presentation] 新生児期におけるケトン体合成の意義2021

    • Author(s)
      有馬勇一郎
    • Organizer
      第24・25回 日本病態栄養学会年次集会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08520
  • [Presentation] DOHaD学説と心血管疾患 (The concept of DOHaD hypothesis in the cardiovascular field.)2021

    • Author(s)
      有馬勇一郎
    • Organizer
      第124回日本小児科学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K08520
  • [Presentation] Ketone body metabolism in health and diseases.2021

    • Author(s)
      Yuichiro Arima
    • Organizer
      “Korean society for vascular biology and medicine, annual meeting 2021”
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08520
  • [Presentation] Epigenetic Modification by Perinatal Environmental Stress and its Lifelong Effects to Cardiovascular Diseases2019

    • Author(s)
      有馬勇一郎
    • Organizer
      第83回日本循環器学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K16014
  • [Presentation] Cytotoxin-associated Gene-A-seropositivity and Interleukin-1 Polymorphisms Influence the Development and Recurrence of Acute Coronary Syndrome2016

    • Author(s)
      Noriaki Tabata, Takayoshi Yamashita, Tomonori Akasaka, Daisuke Sueta, Yuichiro Arima, Tomokazu Ikemoto, Seiji Hokimoto
    • Organizer
      American Heart Association(AHA)2016ニューオーリンズ
    • Place of Presentation
      米国 ニューオリンズ
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09446
  • [Presentation] In vivo imaging of the coronary circulation of the amphibia2014

    • Author(s)
      Yuichiro Arima
    • Organizer
      第78回日本循環器学会学術集会
    • Place of Presentation
      東京国際フォーラム
    • Data Source
      KAKENHI-PROJECT-25893187
  • [Presentation] In Vivo Imaging of the Coronary Circulation of the Amphibia2014

    • Author(s)
      Yuichiro Arima
    • Organizer
      The 18th international vascular biology meeting
    • Place of Presentation
      京都みやこめっせ
    • Data Source
      KAKENHI-PROJECT-25893187
  • [Presentation] Comparative Anatomy of the Coronary Circulation among Rodent Species2014

    • Author(s)
      Yuichiro Arima
    • Organizer
      The 18th international vascular biology meeting
    • Place of Presentation
      京都みやこめっせ
    • Data Source
      KAKENHI-PROJECT-25893187
  • [Presentation] Slow Growth in Fetal Life as the Risk of Non-Congenital Heart Diseases in Adult

    • Author(s)
      Yuichiro Arima
    • Organizer
      第79回日本循環器学会学術集会
    • Place of Presentation
      大阪リーガロイヤルホテル
    • Year and Date
      2015-04-24 – 2015-04-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-25893187
  • 1.  辻田 賢一 (60571263)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  石井 正将 (70823293)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  Hokimoto Seiji (30535638)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 4.  Baba Masaya (10347304)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  花谷 信介 (40755443)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  高潮 征爾 (50573599)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  西川 里織 (40599213)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  伊賀崎 伴彦 (70315282)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  西谷 正太 (50448495)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  日野 信次朗 (00448523)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  岩瀬 晃康 (10965130)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  山田 敏寛 (20984420)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  瀧原 祐史 (50640140)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  井上 俊洋 (00317025)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  梅本 晃正 (50620225)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  水野 秀信 (00567159)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  泉家 康宏 (10515414)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  SARUWATARI Junji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 19.  中川 和子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 20.  鬼木 健太郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results

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