Otani Naoyuki 大谷直由

… Alternative Names

大谷直由オオタニナオユキ

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Researcher Number	60711819
Other IDs	https://orcid.org/0000-0002-0127-2118
Affiliation (Current)	2025: 大分大学, 医学部, 特任准教授 2025: 獨協医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2025: 獨協医科大学, 医学部, 准教授 2022 – 2023: 大分大学, 医学部, 特任准教授 2014 – 2016: 獨協医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related Except Principal Investigator Basic Section 59010:Rehabilitation science-related / Kidney internal medicine
Keywords	Principal Investigator 薬物動態 / 臨床試験 / 硝酸イソソルビド / Extraction ratio / 肺クリアランス / 薬物クリアランス Except Principal Investigator 運動療法 / オートファジー / 運動 / クラスター無作為化比較試験 … More / 微小循環障害 / 血液流動性 / 生活指導 / 大動脈弁狭窄症 / 肥大型心筋症 / リハビリテーション / 近赤外分光法 / 腎代替療法 / 心血管イベント / 糖尿病性腎症 / 創薬 / トランスポーター / 膜輸送 / 高尿酸血症 / 尿酸 Less

The role of cardiac rehabilitation and autophagy in endotype-specific management in of ischemia with non-obstructive coronary artery disease
- Principal Investigator
  
  安隆則
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Dokkyo Medical University
The effect of vigorous exercise instruction using IoT on musle strength, exercise capacity and prognosis
- Principal Investigator
  
  上野明日香 (栗原明日香)
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Dokkyo Medical University
Exercise prescription and lifestyle guidance for hypertrophic obstructive cardiomyopathy and aortic stenosis
- Principal Investigator
  
  巴崇
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Dokkyo Medical University
薬物クリアランスを行う臓器としての新たな肺の生理的役割の解明Principal Investigator
- Principal Investigator
  
  大谷直由
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Oita University
Evaluation of 3-factor model (3F) of renal urate transport that may avoid less side-effect of druf-induced hyperuricemia.
- Principal Investigator
  
  Anzai Naohiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Chiba University
  Dokkyo Medical University

All 2024 2017 2016 Other

All Journal Article Presentation

[Journal Article] Relationship Between Increased Oxygen Uptake and Lactate Production With Progressive Incremental Electrode Skeletal Muscle Stimulation: A Pilot Study2024
- Author(s)
  Tamura Yuma、Ochiai Kaori、Takahashi Momo、Takahashi Harunori、Tomoe Takashi、Sugiyama Takushi、Otani Naoyuki、Sugimura Hiroyuki、Toyoda Shigeru、Yasu Takanori
- Journal Title
  
  Cureus
  
  Volume: -
- DOI
  10.7759/cureus.51919
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K19350, KAKENHI-PROJECT-22K11292, KAKENHI-PROJECT-23K10512
[Journal Article] Roles of organic anion transporters (OATs) in renal proximal tubules and their localization.2017
- Author(s)
  Otani N, Ouchi M, Hayashi K, Jutabha P, Anzai N.
- Journal Title
  
  Anat Sci Int
  
  Volume: 92 Issue: 2 Pages: 200-206
- DOI
  10.1007/s12565-016-0369-3
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461258
[Journal Article] Effects of Uric Acid on the NO Production of HUVECs and its Restoration by Urate Lowering Agents.2016
- Author(s)
  Mishima M, Anzai N, et al.
- Journal Title
  
  Drug Res
  
  Volume: 66 Issue: 05 Pages: 270-274
- DOI
  10.1055/s-0035-1569405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670600, KAKENHI-PROJECT-25461057, KAKENHI-PROJECT-26461258
[Journal Article] Molecular mechanism of urate-lowering effects of anserine nitrate2016
- Author(s)
  Otsuka Y, Ohno Y, Morita A, Otani N, Jutabha P, Ouchi M, Tsuruoka S, Anzai N
- Journal Title
  
  Gout Nucleic Acid Metabol
  
  Volume: 40 Pages: 137-143
- NAID
  130005251395
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461258
[Presentation] 腎尿酸排泄低下型動物モデルの創製とカルシウム拮抗薬の尿酸降下作用の検討2016
- Author(s)
  堀　貴行、大谷直由、大野雄太、大内基氏、福田宏嗣、安西尚彦
- Organizer
  第８9回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-26461258
[Presentation] ヒトの血清尿酸値制御の分子機序2016
- Author(s)
  安西尚彦、大内基司、大谷直由、JUTABHA Promsuk
- Organizer
  第39回日本高血圧学会総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-09-30
- Invited
- Data Source
  KAKENHI-PROJECT-26461258
[Presentation] アンセリンによる尿酸降下作用の分子機序解明2016
- Author(s)
  大塚裕介、森田亜州華、堀　貴行、大谷直由、Jutabha P, 大内基氏、鶴岡秀一、安西尚彦
- Organizer
  第49回日本痛風・核酸代謝学会総会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府・豊中市）
- Year and Date
  2016-02-18
- Data Source
  KAKENHI-PROJECT-26461258
[Presentation] Monocarboxylate transporter 9 is a novel rate transporter in kidney.2016
- Author(s)
  Jutabha P, Otani N, Ouchi M, Anzai N.
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター（北海道・札幌市）
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-26461258
[Presentation] ヒトの尿酸代謝：オーバービュー
- Author(s)
  安西尚彦, 大内基司, 大谷直由, Promsuk Jutabha
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-26461258
[Presentation] Ca拮抗薬による尿酸降下作用の解析
- Author(s)
  土屋豪, 鬼澤信之, 堀貴行, Promsuk Jutabha, 大谷直由, 長谷川元, 福田宏嗣, 安西尚彦
- Organizer
  第37回日本高血圧学会総会
- Place of Presentation
  横浜
- Year and Date
  2014-10-17 – 2014-10-19
- Data Source
  KAKENHI-PROJECT-26461258
[Presentation] 尿酸トランスポーター研究　最近の展開
- Author(s)
  安西尚彦, 大内基司, 大谷直由, Promsuk Jutabha
- Organizer
  第48回日本痛風・核酸代謝学会総会
- Place of Presentation
  東京
- Year and Date
  2015-02-19 – 2015-02-20
- Invited
- Data Source
  KAKENHI-PROJECT-26461258

1. 安隆則 (40265278)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. 田村由馬 (60727585)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 高根沢聡太 (80969197)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Anzai Naohiko (70276054)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
5. SATO Motoyasu (20418891)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. OHBAYASHI Tetsuya (80348804)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. JUTABHA Promsuk (90541748)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
8. 大内基司 (20409155)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
9. 上野明日香 (50725546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 中谷祐己 (10438723)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 巴崇 (80815374)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 内山浩志 (00711318)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 明石嘉浩 (40350615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 前嶋康浩 (40401393)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 楠瀬賢也 (70507649)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 杉山拓史 (70810927)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 阿部七郎 (80275718)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 田口功 (80316570)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 豊田茂 (80332998)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. HAYASHI Keitaro

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. MORITA Asuka

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
22. NOHARA Masakatsu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. WAKASHIN Hidefumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. TSUCHIYA Go

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
25. HORI Takayuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
26. KANO Yuji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. ONIZAWA Nobuyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
28. OTSUKA Yusuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
29. OHNO Yuta

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
30. ENDOU Hitoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. KIMURA Toru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. TAMAI Ikumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. Wempe Michael F.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Otani Naoyuki 大谷 直由

大谷 直由 オオタニ ナオユキ

Research Projects

Research Products

Co-Researchers

The role of cardiac rehabilitation and autophagy in endotype-specific management in of ischemia with non-obstructive coronary artery disease

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The effect of vigorous exercise instruction using IoT on musle strength, exercise capacity and prognosis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exercise prescription and lifestyle guidance for hypertrophic obstructive cardiomyopathy and aortic stenosis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

薬物クリアランスを行う臓器としての新たな肺の生理的役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Evaluation of 3-factor model (3F) of renal urate transport that may avoid less side-effect of druf-induced hyperuricemia.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Relationship Between Increased Oxygen Uptake and Lactate Production With Progressive Incremental Electrode Skeletal Muscle Stimulation: A Pilot Study2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Roles of organic anion transporters (OATs) in renal proximal tubules and their localization.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of Uric Acid on the NO Production of HUVECs and its Restoration by Urate Lowering Agents.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Molecular mechanism of urate-lowering effects of anserine nitrate2016

Author(s)

Journal Title

NAID

Data Source

[Presentation] 腎尿酸排泄低下型動物モデルの創製とカルシウム拮抗薬の尿酸降下作用の検討2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ヒトの血清尿酸値制御の分子機序2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] アンセリンによる尿酸降下作用の分子機序解明2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Monocarboxylate transporter 9 is a novel rate transporter in kidney.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ヒトの尿酸代謝：オーバービュー

Otani Naoyuki 大谷直由

大谷直由オオタニナオユキ

[Presentation] 尿酸トランスポーター研究　最近の展開