Matsushita Masaki 松下雅樹

Researcher Number	60721115
Affiliation (Current)	2025: 名古屋大学, 医学部附属病院, 病院講師 2025: 名古屋大学, 医学系研究科, 特任助教
Affiliation (based on the past Project Information) *help	2021 – 2025: 名古屋大学, 医学部附属病院, 病院講師 2020 – 2024: 名古屋大学, 医学系研究科, 特任助教 2020: 名古屋大学, 医学系研究科, 寄附講座特任助教 2019: 名古屋大学, 医学系研究科, 寄附講座助教 2015 – 2018: 名古屋大学, 医学部附属病院, 病院助教
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related / Orthopaedic surgery Except Principal Investigator Basic Section 56020:Orthopedics-related / Orthopaedic surgery / Basic Section 57040:Regenerative dentistry and dental engineering-related / Basic Section 57070:Developmental dentistry-related
Keywords	Principal Investigator メクロジン / 低身長 / FGFR3 / 軟骨無形成症 / 脊柱管狭窄症 / 大後頭孔狭窄 / 大後頭孔 / 骨質 / 骨密度 Except Principal Investigator 軟骨無形成症 … More / FGFR3 / メクロジン / 骨形成 / ペルテス病 / IL-6 / TLR4拮抗薬 / 骨壊死 / モデルマウス / 骨伸長 / 骨再生 / 塩酸メクリジン / 骨延長 / Runx2 / ランソプラゾール / ドラッグリポジショニング / 骨形成促進 / orthopaedic disease / drug repositioning / 間葉系幹細胞 / 骨髄間質細胞 / シングルセル解析 / 細胞系譜追跡 / 骨格幹細胞 / 化合物ライブラリー / 線維化 / ドッキングシミュレーション / de novo創薬 / 骨形成促進薬 / ゼブラフィッシュモデル / 低リン血症性くる病 / FGFR3インヒビター / 局所投与 / TLR4阻害薬 / 抗IL-6受容体抗体 / 尾部懸垂 / 圧潰 / 虚血性骨壊死 / 水溶性ランソプラゾール / 海綿骨 / empty lacunae / 骨吸収 / 破骨細胞 / 骨延長術 / 軟骨変性 / 薬効薬理作用 / 変形性関節症 / 骨軟骨機能 / 生体材料 / トランスレーショナルリサーチ / 骨折 / 骨欠損 / コンビネーションデバイス / 骨欠損修復 / 骨折治癒促進 / 人工骨 / 薬効スクリーニング / ドラッグスクリーニング / ALK2 / Id1 / 異所性骨化 / ドラッグ・リポジショニング / 進行性骨化性線維異形成症 Less

新規FGFR3インヒビターの骨軟骨代謝における効果と作用機序の検討Principal Investigator
- Principal Investigator
  
  松下雅樹
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Nagoya University
四次元的細胞系譜追跡による軟骨無形成症のメカニズム解明と治療応用
- Principal Investigator
  
  森田淳平
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Nagasaki University
整形外科領域の新規治療に向けたdrug repositioning戦略
- Principal Investigator
  
  今釜史郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Nagoya University
小児大腿骨頭壊死症の線維化を中心とした病態解明と新規骨再生促進薬の開発
- Principal Investigator
  
  三島健一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Nagoya University
FGFR3インヒビターのマウスモデルへの長期投与と作用機序の検討Principal Investigator
- Principal Investigator
  
  松下雅樹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Nagoya University
Development of therapeutic drugs fro achondroplasia-Examination of FGFR3 inhibitory effects of meclizine hydrochloride
- Principal Investigator
  
  Kitoh Hiroshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Aichi Children’s Health and Medical Center
多階層シングルセル解析を応用した骨再生機構の解明と新規再生療法の基盤構築
- Principal Investigator
  
  松下祐樹
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57040:Regenerative dentistry and dental engineering-related
- Research Institution
  Nagasaki University
骨延長マウスモデルにおけるメクロジンのFGFR3抑制効果の検討
- Principal Investigator
  
  神谷庸成
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Nagoya University
ドラッグリポジショニングによるペルテス病の新規治療法の開発
- Principal Investigator
  
  三島健一
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Nagoya University
FGFR3インヒビターの局所投与による骨伸長促進効果の検討
- Principal Investigator
  
  長田侃
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Nagoya University
新規軟骨無形成症治療薬開発研究Principal Investigator
- Principal Investigator
  
  松下雅樹
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Nagoya University
Investigation of osteochondral function via activation of FGFR3 signaling
- Principal Investigator
  
  Kitoh Hiroshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya University
Drug repositioning for successful healing of bone fractures or defects
- Principal Investigator
  
  MISHIMA KENICHI
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya University
Animal study for evaluating the effect of meclozine on FGFR3 signalingPrincipal Investigator
- Principal Investigator
  
  Matsushita Masaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya University
Development of therapeutic drugs for fibrodysplasia ossificans progressiva by drug repositioning strategies
- Principal Investigator
  
  Kitoh Hiroshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Quality of life in adult patients with developmental dysplasia of the hip who were treated for hip dislocation during childhood2024
- Author(s)
  Sawamura Kenta、Kitoh Hiroshi、Matsushita Masaki、Mishima Kenichi、Kamiya Yasunari、Imagama Shiro
- Journal Title
  
  Journal of Pediatric Orthopaedics B
  
  Volume: - Issue: 1 Pages: 38-43
- DOI
  10.1097/bpb.0000000000001173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09573, KAKENHI-PROJECT-22K09304
[Journal Article] Long-term oral meclozine administration improves survival rate and spinal canal stenosis during postnatal growth in a mouse model of achondroplasia in both sexes2024
- Author(s)
  Funahashi Hiroto、Matsushita Masaki、Esaki Ryusaku、Mishima Kenichi、Ohkawara Bisei、Kamiya Yasunari、Takegami Yasuhiko、Ohno Kinji、Kitoh Hiroshi、Imagama Shiro
- Journal Title
  
  JBMR Plus
  
  Volume: 8 Issue: 4
- DOI
  10.1093/jbmrpl/ziae018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09573, KAKENHI-PROJECT-19K09646, KAKENHI-PROJECT-22K09304, KAKENHI-PROJECT-22K09398, KAKENHI-PROJECT-23K08610, KAKENHI-PROJECT-21H03063
[Journal Article] Single-Cell RNA-Sequencing Reveals the Skeletal Cellular Dynamics in Bone Repair and Osteoporosis2023
- Author(s)
  Wu Sixun、Ohba Shinsuke、Matsushita Yuki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 12 Pages: 9814-9814
- DOI
  10.3390/ijms24129814
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19612, KAKENHI-PROJECT-20KK0356, KAKENHI-PROJECT-23K21487, KAKENHI-PROJECT-23K21494
[Journal Article] Multi-omics analysis in developmental bone biology2023
- Author(s)
  Matsushita Yuki、Noguchi Azumi、Ono Wanida、Ono Noriaki
- Journal Title
  
  Japanese Dental Science Review
  
  Volume: 59 Pages: 412-420
- DOI
  10.1016/j.jdsr.2023.10.006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0356, KAKENHI-PROJECT-23K21487
[Journal Article] Prognostic value of bone resorption pattern in the anterior portion of the femoral head in Legg-Calve-Perthes disease2023
- Author(s)
  Mishima Kenichi、Kamiya Yasunari、Matsushita Masaki、Imagama Shiro
- Journal Title
  
  Journal of Children's Orthopaedics
  
  Volume: 17 Issue: 3 Pages: 197-204
- DOI
  10.1177/18632521231164985
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09573, KAKENHI-PROJECT-22K09304
[Journal Article] Endosteal stem cells at the bone‐blood interface: A double‐edged sword for rapid bone formation2023
- Author(s)
  Matsushita Yuki、Liu Jialin、Chu Angel Ka Yan、Ono Wanida、Welch Joshua D.、Ono Noriaki
- Journal Title
  
  BioEssays
  
  Volume: 46 Issue: 3 Pages: 2300173-2300173
- DOI
  10.1002/bies.202300173
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0356, KAKENHI-PROJECT-23K21487
[Journal Article] Acute osteomyelitis of the patella due to Pseudomonas aeruginosa in an immunocompetent child: A case report2023
- Author(s)
  Kamiya Yasunari、Mishima Kenichi、Tanaka Tetsuji、Sawamura Kenta、Matsushita Masaki、Imagama Shiro
- Journal Title
  
  Medicine
  
  Volume: 102 Issue: 7 Pages: e33012-e33012
- DOI
  10.1097/md.0000000000033012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09573, KAKENHI-PROJECT-19K09646, KAKENHI-PROJECT-22K09304, KAKENHI-PROJECT-22K09398
[Journal Article] 4歳以降に診断された発育性股関節形成不全症3例に対するオーバーヘッド牽引法の短期治療成績2023
- Author(s)
  三島　健一、神谷　庸成、松下　雅樹、今釜　史郎
- Journal Title
  
  中部日本整形外科災害外科学会雑誌
  
  Volume: 66 Pages: 245-246
- Data Source
  KAKENHI-PROJECT-19K09573
[Journal Article] Dobbs法による初期治療を行った先天性垂直距骨の治療経験2023
- Author(s)
  三島　健一、神谷　庸成、澤村　健太、松下　雅樹、今釜　史郎
- Journal Title
  
  日本小児整形外科学会雑誌
  
  Volume: 32 Pages: 6-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09304
[Journal Article] Activated FGFR3 suppresses bone regeneration and bone mineralization in an ovariectomized mouse model2023
- Author(s)
  Kawashima Itaru、Matsushita Masaki、Mishima Kenichi、Kamiya Yasunari、Osawa Yusuke、Ohkawara Bisei、Ohno Kinji、Kitoh Hiroshi、Imagama Shiro
- Journal Title
  
  BMC Musculoskeletal Disorders
  
  Volume: 24 Issue: 1 Pages: 200-200
- DOI
  10.1186/s12891-023-06318-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09646, KAKENHI-PROJECT-20K09477, KAKENHI-PROJECT-22K09398, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-21H03063, KAKENHI-PROJECT-21K06392
[Journal Article] 4歳以降に診断された発育性股関節形成不全症3例に対するオーバーヘッド牽引法の短期治療成績2023
- Author(s)
  三島　健一、神谷　庸成、松下　雅樹、今釜　史郎
- Journal Title
  
  中部日本整形外科災害外科学会雑誌
  
  Volume: 66 Pages: 245-246
- Data Source
  KAKENHI-PROJECT-22K09304
[Journal Article] Cellular dynamics of distinct skeletal cells and the development of osteosarcoma2023
- Author(s)
  Otani Shohei、Ohnuma Mizuho、Ito Kosei、Matsushita Yuki
- Journal Title
  
  Frontiers in Endocrinology
  
  Volume: 14 Pages: 1181204-1181204
- DOI
  10.3389/fendo.2023.1181204
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19612, KAKENHI-PROJECT-20KK0356, KAKENHI-PROJECT-21H03113, KAKENHI-PROJECT-23K21487
[Journal Article] Hes1 marks peri-condensation mesenchymal cells that generate both chondrocytes and perichondrial cells in early bone development2023
- Author(s)
  Matsushita Yuki、Manabe Hiroaki、Ohyama Takahiro、Nakamura Shogo、Nagata Mizuki、Ono Wanida、Ono Noriaki
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299 Issue: 6 Pages: 104805-104805
- DOI
  10.1016/j.jbc.2023.104805
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0356, KAKENHI-PROJECT-23K21487
[Journal Article] Bone marrow endosteal stem cells dictate active osteogenesis and aggressive tumorigenesis2023
- Author(s)
  Matsushita Yuki、Liu Jialin、Chu Angel Ka Yan、Tsutsumi-Arai Chiaki、Nagata Mizuki、Arai Yuki、Ono Wanida、Yamamoto Kouhei、Saunders Thomas L.、Welch Joshua D.、Ono Noriaki
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 2383-2383
- DOI
  10.1038/s41467-023-38034-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19612, KAKENHI-PROJECT-20KK0356, KAKENHI-PROJECT-18K17136, KAKENHI-PROJECT-23K21487
[Journal Article] Phase 1b study on the repurposing of meclizine hydrochloride for children with achondroplasia2023
- Author(s)
  Matsushita Masaki、Kitoh Hiroshi、Mishima Kenichi、Kamiya Yasunari、Kato Daisaku、Takemoto Genta、Sawamura Kenta、Ueno Shinji、Yasuhiro Nakai、Nishida Kazuki、Imagama Shiro
- Journal Title
  
  PLOS ONE
  
  Volume: 18 Issue: 7 Pages: e0283425-e0283425
- DOI
  10.1371/journal.pone.0283425
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09573, KAKENHI-PROJECT-19K09646, KAKENHI-PROJECT-22K09304, KAKENHI-PROJECT-22K09398, KAKENHI-PROJECT-23K08610, KAKENHI-PROJECT-21H03063
[Journal Article] Dobbs法による初期治療を行った先天性垂直距骨の治療経験2023
- Author(s)
  三島　健一、神谷　庸成、澤村　健太、松下　雅樹、今釜　史郎
- Journal Title
  
  日本小児整形外科学会雑誌
  
  Volume: 32 Pages: 6-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09573
[Journal Article] Meclozine Attenuates the MARK Pathway in Mammalian Chondrocytes and Ameliorates FGF2-Induced Bone Hyperossification in Larval Zebrafish2022
- Author(s)
  Takemoto Genta、Matsushita Masaki、Okamoto Takaaki、Ito Toshinari、Matsuura Yuki、Takashima Chieko、Chen-Yoshikawa Toyofumi Fengshi、Ebi Hiromichi、Imagama Shiro、Kitoh Hiroshi、Ohno Kinji、Hosono Yasuyuki
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 9 Pages: 694018-694018
- DOI
  10.3389/fcell.2021.694018
- NAID
  120007190703
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-21H03063, KAKENHI-PROJECT-19K09646, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-20H03561
[Journal Article] Gain-of-Function of FGFR3 Accelerates Bone Repair Following Ischemic Osteonecrosis in Juvenile Mice2022
- Author(s)
  Kato Daisaku、Matsushita Masaki、Takegami Yasuhiko、Mishima Kenichi、Kamiya Nobuhiro、Osawa Yusuke、Imagama Shiro、Kitoh Hiroshi
- Journal Title
  
  Calcified Tissue International
  
  Volume: 111 Issue: 6 Pages: 622-633
- DOI
  10.1007/s00223-022-01019-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09646, KAKENHI-PROJECT-22K09398, KAKENHI-PROJECT-21H03063, KAKENHI-PROJECT-19K09563
[Journal Article] Inconvenience and adaptation in Japanese adult achondroplasia and hypochondroplasia: A cross-sectional study2022
- Author(s)
  Ajimi A, Matsushita M, Mishima K, Haga N, Fujiwara S, Ozono K, Kubota T, Kitaoka T, Imagama S, Kitoh H
- Journal Title
  
  Clinical Pediatric Endocrinology
  
  Volume: 31 Issue: 1 Pages: 18-24
- DOI
  10.1297/cpe.2021-0043
- NAID
  130008138931
- ISSN
  0918-5739, 1347-7358
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03063, KAKENHI-PROJECT-19K09573, KAKENHI-PROJECT-19K09646
[Journal Article] Disease-specific complications and multidisciplinary interventions in achondroplasia.2022
- Author(s)
  Kitoh H, Matsushita M, Mishima K, Kamiya Y, Sawamura K
- Journal Title
  
  J Bone Miner Metab
  
  Volume: 40 Issue: 2 Pages: 189-195
- DOI
  10.1007/s00774-021-01298-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H03063, KAKENHI-PROJECT-19K09573, KAKENHI-PROJECT-19K09646
[Journal Article] Predictive ability of inflammatory markers and laboratory parameters in Legg-Calve-Perthes disease: A single-center retrospective comparative study.2022
- Author(s)
  Mishima K, Kamiya Y, Matsushita M, Imagama S, Kitoh H
- Journal Title
  
  Medicine
  
  Volume: 101 Issue: 11
- DOI
  10.1097/md.0000000000029061
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03063, KAKENHI-PROJECT-19K09573, KAKENHI-PROJECT-22K09304
[Journal Article] Meclozine ameliorates bone mineralization and growth plate structure in a mouse model of X-linked hypophosphatemia2022
- Author(s)
  Kamiya Yasunari、Matsushita Masaki、Mishima Kenichi、Ohkawara Bisei、Michigami Toshimi、Imagama Shiro、Ohno Kinji、Kitoh Hiroshi
- Journal Title
  
  Experimental and Therapeutic Medicine
  
  Volume: 25 Issue: 1 Pages: 39-39
- DOI
  10.3892/etm.2022.11738
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09646, KAKENHI-PROJECT-20K09477, KAKENHI-PROJECT-22K09398, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-21H03063
[Journal Article] Bypass of epiphyseal fragmentation following early Salter innominate osteotomy and its clinical relevance in Legg-Calve-Perthes disease.2022
- Author(s)
  Mishima K, Kamiya Y, Matsushita M, Imagama S, Kitoh H
- Journal Title
  
  J Pediatr Orthop
  
  Volume: 42 Issue: 5 Pages: 239-245
- DOI
  10.1097/bpo.0000000000002089
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H03063, KAKENHI-PROJECT-19K09573, KAKENHI-PROJECT-19K09646, KAKENHI-PROJECT-22K09304, KAKENHI-PROJECT-22K09398
[Journal Article] A cross-sectional nationwide survey of osteosclerotic skeletal dysplasia in Japan.2022
- Author(s)
  Sawamura K, Mishima K, Matsushita M, Kamiya Y, Kitoh H
- Journal Title
  
  J Orthop Sci
  
  Volume: - Issue: 5 Pages: 1139-1142
- DOI
  10.1016/j.jos.2021.05.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H03063, KAKENHI-PROJECT-19K09573, KAKENHI-PROJECT-19K09646, KAKENHI-PROJECT-22K09398
[Journal Article] Guided growth for coronal lower limb deformities in skeletal dysplasia.2022
- Author(s)
  Kitoh H, Kamiya Y, Mishima K, Matsushita M, Kaneko H, Kitamura A, Sawamura K, Matsuyama S
- Journal Title
  
  J Pediatr Orthop B
  
  Volume: - Issue: 2 Pages: 157-164
- DOI
  10.1097/bpb.0000000000000965
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H03063, KAKENHI-PROJECT-19K09573, KAKENHI-PROJECT-19K09646, KAKENHI-PROJECT-22K09398
[Journal Article] Asfotase alfa has a limited effect in improving the bowed limbs in perinatal benign hypophosphatasia: A case report2021
- Author(s)
  Matsushita M, Mishima K, Nagata T, Kamiya Y, Imagama S, Kitoh H
- Journal Title
  
  Clin Pediatr Endocrinol
  
  Volume: 30 Issue: 1 Pages: 53-56
- DOI
  10.1297/cpe.30.53
- NAID
  130007966048
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09646, KAKENHI-PROJECT-21H03063, KAKENHI-PROJECT-19K09573
[Journal Article] Health-related Quality of Life in Adult Patients with Multiple Epiphyseal Dysplasia and Spondyloepiphyseal Dysplasia2021
- Author(s)
  Matsushita M, Mishima K, Kamiya Y, Haga N, Fujiwara S, Ozono K, Kubota T, Kitaoka T, Imagama S, Kitoh H
- Journal Title
  
  Progress in Rehabilitation Medicine
  
  Volume: 6 Issue: 0 Pages: n/a
- DOI
  10.2490/prm.20210048
- NAID
  130008125972
- ISSN
  2432-1354
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03063, KAKENHI-PROJECT-19K09573, KAKENHI-PROJECT-19K09646
[Journal Article] Pharmacokinetics and safety after once and twice a day doses of meclizine hydrochloride administered to children with achondroplasia2020
- Author(s)
  Kitoh Hiroshi、Matsushita Masaki、Mishima Kenichi、Nagata Tadashi、Kamiya Yasunari、Ueda Kohei、Kuwatsuka Yachiyo、Morikawa Hiroshi、Nakai Yasuhiro、Ishiguro Naoki
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Issue: 4 Pages: e0229639-e0229639
- DOI
  10.1371/journal.pone.0229639
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09573, KAKENHI-PROJECT-19K09646, KAKENHI-PROJECT-19H03779
[Journal Article] Impact of fracture characteristics and disease-specific complications on health-related quality of life in osteogenesis imperfecta2020
- Author(s)
  Matsushita M, Mishima K, Yamashita S, Haga N, Fujiwara S, Ozono K, Kubota T, Kitaoka T, Ishiguro N, Kitoh H
- Journal Title
  
  J Bone Miner Metab
  
  Volume: 38 Issue: 1 Pages: 109-116
- DOI
  10.1007/s00774-019-01033-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04312
[Journal Article] Severe achondroplasia due to two de novo variants in the transmembrane domain of FGFR3 on the same allele: A case report.2020
- Author(s)
  Nagata T, Matsushita M, Mishima K, Kamiya Y, Kato K, Toyama M, Ogi T, Ishiguro N, Kitoh H.
- Journal Title
  
  Molecular Genetics & Genomic Medicine
  
  Volume: 8 Issue: 3 Pages: 1-1
- DOI
  10.1002/mgg3.1148
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H00783, KAKENHI-PROJECT-17H04312, KAKENHI-PROJECT-18H03372, KAKENHI-PROJECT-19K09573
[Journal Article] A retrospective comparative study of corrective osteotomy for tibial deformities with the multiaxial correction fixator and the circular fixator2020
- Author(s)
  Matsushita M, Kitoh H, Mishima K, Nagata T, Kamiya Y, Kaneko H, Hattori T, Ishiguro N
- Journal Title
  
  J Clin Orthop Trauma
  
  Volume: 11(Suppl 4) Pages: S621-S625
- DOI
  10.1016/j.jcot.2020.05.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09646
[Journal Article] Effect of periosteal resection on longitudinal bone growth in a mouse model of achondroplasia2020
- Author(s)
  Kaneko S, Matsushita M, Mishima K, Takegami Y, Imagama S, Kitoh H
- Journal Title
  
  Bone Rep.
  
  Volume: 13 Pages: 100708-100708
- DOI
  10.1016/j.bonr.2020.100708
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09646
[Journal Article] Legg‐Calve‐Perthes disease in a patient with Bardet‐Biedl syndrome: A case report of a novelMKKS/BBS6mutation2020
- Author(s)
  Mishima Kenichi、Fujita Atsushi、Mizuno Seiji、Matsushita Masaki、Nagata Tadashi、Kamiya Yasunari、Miyake Noriko、Matsumoto Naomichi、Imagama Shiro、Kitoh Hiroshi
- Journal Title
  
  Clinical Case Reports
  
  Volume: 8 Issue: 12 Pages: 3110-3115
- DOI
  10.1002/ccr3.3357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09573
[Journal Article] Lower limb pain following allogeneic hematopoietic stem cell transplantation in Japanese children2019
- Author(s)
  Mishima Kenichi、Kitoh Hiroshi、Matsushita Masaki、Nagata Tadashi、Kamiya Yasunari、Takahashi Yoshiyuki、Ishiguro Naoki
- Journal Title
  
  Journal of Orthopaedic Science
  
  Volume: 26 Issue: 4 Pages: 1-1
- DOI
  10.1016/j.jos.2019.07.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04312, KAKENHI-PROJECT-16K10854, KAKENHI-PROJECT-19K09573
[Journal Article] Physical, Mental, and Social Problems of Adolescent and Adult Patients with Achondroplasia2019
- Author(s)
  Matsushita Masaki、Kitoh Hiroshi、Mishima Kenichi、Yamashita Satoshi、Haga Nobuhiko、Fujiwara Sayaka、Ozono Keiichi、Kubota Takuo、Kitaoka Taichi、Ishiguro Naoki
- Journal Title
  
  Calcified Tissue International
  
  Volume: 104 Issue: 4 Pages: 364-372
- DOI
  10.1007/s00223-019-00518-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K17890, KAKENHI-PROJECT-16H05446, KAKENHI-PROJECT-17H04312, KAKENHI-PROJECT-18H03125, KAKENHI-PROJECT-19K09573, KAKENHI-PROJECT-16K10854
[Journal Article] Comparison of surgical and nonsurgical containment methods for patients with Legg-Calv?-Perthes disease of the onset ages between 6.0 and 8.0 years2019
- Author(s)
  Kaneko Hiroshi、Kitoh Hiroshi、Mishima Kenichi、Matsushita Masaki、Hattori Tadashi、Noritake Koji、Ishiguro Naoki、Yoshihashi Yuji
- Journal Title
  
  Journal of Pediatric Orthopaedics B
  
  Volume: - Issue: 6 Pages: 1-1
- DOI
  10.1097/bpb.0000000000000710
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09573, KAKENHI-PROJECT-17H04312, KAKENHI-PROJECT-16K10854
[Journal Article] Chronic lateral epiphyseal separation of the proximal tibia causes late-onset tibia vara.2018
- Author(s)
  Hasegawa S, Kitoh H, Matsushita M, Mishima K, Kadono I, Sugiura H, Kitamura A, Ishiguro N
- Journal Title
  
  J Pediatr Orthop B.
  
  Volume: 27 Issue: 1 Pages: 31-34
- DOI
  10.1097/bpb.0000000000000430
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10854, KAKENHI-PROJECT-16H05446, KAKENHI-PROJECT-15K15548, KAKENHI-PROJECT-17H04312
[Journal Article] Extensive Bone Lengthening for a Patient with Linear Morphea2018
- Author(s)
  Mishima K, Kitoh H, Matsushita M, Nagata T, Kamiya Y, Ishiguro N.
- Journal Title
  
  Case Rep Orthop.
  
  Volume: - Pages: 1-5
- DOI
  10.1155/2018/4535804
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10854, KAKENHI-PROJECT-16H05446, KAKENHI-PROJECT-17H04312
[Journal Article] Changes in the range of motion of the lower limb joints during extensive tibial lengthening in achondroplasia2018
- Author(s)
  Kadono Izumi、Kitoh Hiroshi、Mishima Kenichi、Matsushita Masaki、Sato Koji、Kako Masato、Ishiguro Naoki
- Journal Title
  
  Journal of Pediatric Orthopaedics B
  
  Volume: 27 Issue: 6 Pages: 535-540
- DOI
  10.1097/bpb.0000000000000526
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05446, KAKENHI-PROJECT-17H04312
[Journal Article] 脚長差に伴う機能性側弯の特徴2018
- Author(s)
  三島健一、鬼頭　浩史、松下　雅樹、門野　泉、長田侃、西田　佳弘、石黒　直樹
- Journal Title
  
  日本小児整形外科学会雑誌
  
  Volume: 27 Pages: 105-109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10854
[Journal Article] A Mouse Distraction Osteogenesis Model2018
- Author(s)
  Fujio Masahito、Osawa Yusuke、Matsushita Masaki、Ogisu Kota、Tsuchiya Shuhei、Kitoh Hiroshi、Hibi Hideharu
- Journal Title
  
  Journal of Visualized Experiments
  
  Volume: 141 Issue: 141 Pages: 0-0
- DOI
  10.3791/57925
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11802, KAKENHI-PROJECT-16H05446, KAKENHI-PROJECT-16H05540, KAKENHI-PROJECT-17H04312
[Journal Article] Activated FGFR3 prevents subchondral bone sclerosis during the development of osteoarthritis in transgenic mice with achondroplasia.2018
- Author(s)
  6.Okura T, Matsushita M, Mishima K, Esaki R, Seki T, Ishiguro N, Kitoh H.
- Journal Title
  
  J Orthop Res
  
  Volume: 36(1) Issue: 1 Pages: 300-308
- DOI
  10.1002/jor.23608
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05446, KAKENHI-PROJECT-17H04312, KAKENHI-PROJECT-15K10439, KAKENHI-PROJECT-15K15548
[Journal Article] A novel heterozygous mutation in the T-box protein 4 gene in an adult case of small patella syndrome2018
- Author(s)
  Oda T, Matsushita M, Ono Y, Kitoh H, Sakai T
- Journal Title
  
  J Orthop Case Rep
  
  Volume: 8 Pages: 85-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04312
[Journal Article] Early radiographic risk factors for rigid relapse in idiopathic clubfoot treated with the Ponseti method.2017
- Author(s)
  Mishima K, Kitoh H, Matsushita M, Sugiura H, Hasegawa S, Kitamura A, Nishida Y, Ishiguro N.
- Journal Title
  
  Foot Ankle Surg.
  
  Volume: ー Issue: 6 Pages: 30126-1
- DOI
  10.1016/j.fas.2017.06.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10854, KAKENHI-PROJECT-16H05446, KAKENHI-PROJECT-17H04312, KAKENHI-PROJECT-15K15548
[Journal Article] Is the timing of surgery associated with avascular necrosis after unstable slipped capital femoral epiphysis? A multicenter study.2017
- Author(s)
  Kohno Y, Nakashima Y, Kitano T, Irie T, Kita A, Nakamura T, Endo H, Fujii Y, Kuroda T, Mitani S, Kitoh H, Matsushita M, Hattori T, Iwata K, Iwamoto Y.
- Journal Title
  
  J Orthop Sci.
  
  Volume: 22 Issue: 1 Pages: 112-115
- DOI
  10.1016/j.jos.2016.08.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10854, KAKENHI-PROJECT-16H05446, KAKENHI-PROJECT-17H04312, KAKENHI-PROJECT-15K15548
[Journal Article] 小児同種造血幹細胞移植後の下肢痛症例の検討2017
- Author(s)
  三島健一、鬼頭浩史、松下雅樹、門野　泉、杉浦　洋、北村暁子、西田　佳弘、石黒　直樹
- Journal Title
  
  日本小児整形外科学会雑誌
  
  Volume: 26 Pages: 120-124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10854
[Journal Article] Clinical dosage of meclozine promotes longitudinal bone growth, bone volume, and trabecular bone quality in transgenic mice with achondroplasia.2017
- Author(s)
  Matsushita M, Esaki R, Mishima K, Ishiguro N, Ohno K, Kitoh H.
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Issue: 1 Pages: 7371-7371
- DOI
  10.1038/s41598-017-07044-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10854, KAKENHI-PROJECT-16H05446, KAKENHI-PROJECT-17H04312, KAKENHI-PROJECT-15K10439, KAKENHI-PROJECT-15K15548
[Journal Article] Percutaneous pinning after prolonged skeletal traction with the hip in a flexed position for unstable slipped capital femoral epiphysis: A case series of 11 patients.2017
- Author(s)
  Matsushita M, Mishima K, Iwata K, Hattori T, Ishiguro N, Kitoh H.
- Journal Title
  
  Medicine (Baltimore).
  
  Volume: 96 Issue: 19 Pages: e6662-e6662
- DOI
  10.1097/md.0000000000006662
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10854, KAKENHI-PROJECT-16H05446, KAKENHI-PROJECT-17H04312, KAKENHI-PROJECT-15K15548
[Journal Article] Activated FGFR3 promotes bone formation via accelerating endochondral ossification in mouse model of distraction osteogenesis2017
- Author(s)
  Osawa Yusuke、Matsushita Masaki、Hasegawa Sachi、Esaki Ryusaku、Fujio Masahito、Ohkawara Bisei、Ishiguro Naoki、Ohno Kinji、Kitoh Hiroshi
- Journal Title
  
  Bone
  
  Volume: 105 Pages: 42-49
- DOI
  10.1016/j.bone.2017.05.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-16K10854, KAKENHI-PROJECT-16H05446, KAKENHI-PROJECT-17H04312, KAKENHI-PROJECT-15K10439, KAKENHI-PROJECT-15K15548
[Journal Article] Maternal administration of meclozine for the treatment of foramen magnum stenosis in transgenic mice with achondroplasia2017
- Author(s)
  Matsushita M, Mishima K, Esaki R, Ishiguro N, Ohno K, Kitoh H
- Journal Title
  
  J Neurosurg Pediatr
  
  Volume: 19 Issue: 1 Pages: 91-95
- DOI
  10.3171/2016.7.peds16199
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10439, KAKENHI-PROJECT-16K10854, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-16H05446, KAKENHI-PROJECT-17H04312, KAKENHI-PROJECT-15K15548
[Journal Article] Ponseti法におけるX線学的予後予測因子2016
- Author(s)
  三島健一、鬼頭浩史、松下雅樹、門野　泉、杉浦　洋、長谷川幸、北村暁子、西田　佳弘、石黒　直樹
- Journal Title
  
  日本小児整形外科学会雑誌
  
  Volume: 25 Pages: 251-254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10854
[Journal Article] Tranilast stimulates endochondral ossification by upregulating SOX9 and RUNX2 promoters.2016
- Author(s)
  Hasegawa S, Kitoh H, Ohkawara B, Mishima K, Matsushita M, Masuda A, Ishiguro N, Ohno K
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 470(2) Issue: 2 Pages: 356-61
- DOI
  10.1016/j.bbrc.2016.01.044
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249076, KAKENHI-PROJECT-26670660, KAKENHI-PROJECT-25861306, KAKENHI-PROJECT-15K06755, KAKENHI-PROJECT-15K15548
[Journal Article] Clinical Results and Complications of Lower Limb Lengthening for Fibular Hemimelia: A Report of Eight Cases.2016
- Author(s)
  Mishima K, Kitoh H, Iwata K, Matsushita M, Nishida Y, Hattori T, Ishiguro N.
- Journal Title
  
  Medicine (Baltimore)
  
  Volume: 95 Issue: 21 Pages: e3787-e3787
- DOI
  10.1097/md.0000000000003787
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10854, KAKENHI-PROJECT-15K15548
[Journal Article] Characterization of novel Runx2 mutation with alanine tract expansion from Japanese cleidocranial dysplasia patient2016
- Author(s)
  Shibata A, Machida J, Yamaguchi S, Kimura M, Tatematsu T, Miyachi H, Matsushita M, Kitoh H, Ishiguro N, Nakayama A, Higashi Y, Shimozato K, Tokita Y
- Journal Title
  
  Mutagenesis
  
  Volume: 31 Pages: 61-67
- DOI
  10.1093/mutage/gev057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15548
[Journal Article] Low bone mineral density in achondroplasia and hypochondroplasia2015
- Author(s)
  Matsushita M, Kitoh H, Mishima K, Kadono I, Sugiura H, Hasegawa S, Nishida Y, Ishiguro N
- Journal Title
  
  Pediatr Int.
  
  Volume: 印刷中 Issue: 8 Pages: 705-708
- DOI
  10.1111/ped.12890
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10439, KAKENHI-PROJECT-16H05446, KAKENHI-PROJECT-15K15548
[Journal Article] A glutamine repeat variant of the RUNX2 gene causes cleidocranial dysplasia2015
- Author(s)
  Matsushita M, Kitoh H, Subasioglu A, Colak FK, Dundar M, Mishima K, Nishida Y, Ishiguro N
- Journal Title
  
  Mol Syndromol
  
  Volume: 6 Issue: 1 Pages: 50-53
- DOI
  10.1159/000370337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15548
[Journal Article] Congenital myasthenic syndrome in Japan: ethnically unique mutations in muscle nicotinic acetylcholine receptor subunits2015
- Author(s)
  Azuma Y, Nakata T, Tanaka M, Shen X M, Ito M, Iwata S, Okuno T, Nomura Y, Ando N, Ishigaki K, Ohkawara B, Masuda A, Natsume J, Kojima S, Sokabe M, Ohno K
- Journal Title
  
  Neuromuscul Disord
  
  Volume: 25 Issue: 2 Pages: 60-69
- DOI
  10.1210/en.2014-1914
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500469, KAKENHI-ORGANIZER-26108001, KAKENHI-PLANNED-26108006, KAKENHI-PROJECT-26461381, KAKENHI-PROJECT-15K15548
[Presentation] 閉経後マウスモデルにおける変形性膝関節症に対するFGFR3シグナルの効果の検討2024
- Author(s)
  藤井整、松下雅樹、石塚真哉、三島健一、神谷庸成、澤村健太、鬼頭浩史、今釜史郎
- Organizer
  第36回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-22K09398
[Presentation] Meclozine ameliorates osteogenic mineralization of bone marrow-derived mesenchymal stem cells using a mouse model of achondroplasia2024
- Author(s)
  Masaki Matsushita, Itaru Kawashima, Kenichi Mishima, Yasunari Kamiya, Kinji Ohno, Hiroshi Kitoh, Shiro Imagama
- Organizer
  Orthopaedic Research Society 2024 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09398
[Presentation] 閉経後マウスモデルにおける変形性膝関節症に対するFGFR3シグナルの効果の検討2024
- Author(s)
  藤井整、松下雅樹、石塚真哉、三島健一、神谷庸成、澤村健太、鬼頭浩史、今釜史郎
- Organizer
  第36回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] Meclozine ameliorates osteogenic mineralization of bone marrow-derived mesenchymal stem cells using a mouse model of achondroplasia2024
- Author(s)
  Masaki Matsushita, Itaru Kawashima, Kenichi Mishima, Yasunari Kamiya, Kinji Ohno, Hiroshi Kitoh, Shiro Imagama
- Organizer
  Orthopaedic Research Society 2024 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] 多発性軟骨性外骨腫症に対するエイトプレートを用いた脚長補正と下肢アライメント矯正の検討2023
- Author(s)
  松下雅樹、三島健一、神谷庸成、澤村健太、今釜史郎
- Organizer
  第34回日本小児整形外科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] メクロジンの経口投与は軟骨無形成症マウスモデルの脊柱管を拡大し麻痺の発生率を低減する2023
- Author(s)
  船橋洋人、松下雅樹、三島健一、神谷庸成、澤村健太、鬼頭浩史、大野欽司、今釜史郎
- Organizer
  第38回日本整形外科基礎学術集会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] エクソーム解析による骨系統疾患の遺伝学的診断2023
- Author(s)
  三島健一、神谷庸成、澤村健太、松下雅樹、加藤耕治、荻　朋男、今釜史郎、鬼頭浩史
- Organizer
  第35回日本整形外科学会骨系統疾患研究会
- Data Source
  KAKENHI-PROJECT-23K08610
[Presentation] A 14-day repeated oral administration of meclizine in child patients with achondroplasia to evaluate safety and pharmacokinetics2023
- Author(s)
  Masaki Matsushita, Hiroshi Kitoh, Kenichi Mishima, Yasunari Kamiya, Kenta Sawamura, Kazuki Nishida, Yasuhiro Nakai, Shiro Imagama
- Organizer
  ASBMR 2023 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09398
[Presentation] Long-term oral administration of meclozine for the treatment of achondroplasia using a mouse model2023
- Author(s)
  Funahashi H, Matsushita M, Mishima K, Okawara B, Kamiya Y, Ohno K, Kitoh H, Imagama S
- Organizer
  Orthopaedic Research Society 2023 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09398
[Presentation] エクソーム解析による骨系統疾患の遺伝学的診断2023
- Author(s)
  三島　健一、神谷　庸成、澤村　健太、松下　雅樹、加藤　耕治、荻　朋男、今釜　史郎、鬼頭　浩史
- Organizer
  第35回日本整形外科学会骨系統疾患研究会
- Data Source
  KAKENHI-PROJECT-19K09573
[Presentation] 多発性軟骨性外骨腫症に対するエイトプレートを用いた脚長補正と下肢アライメント矯正の検討2023
- Author(s)
  松下雅樹、三島健一、神谷庸成、澤村健太、今釜史郎
- Organizer
  第34回日本小児整形外科学会学術集会
- Data Source
  KAKENHI-PROJECT-22K09398
[Presentation] 軟骨無形成症マウスモデルを用いたFGFR3インヒビターの大後頭孔と脊柱管に対する効果の検討2023
- Author(s)
  松下雅樹、船橋洋人、三島健一、神谷庸成、澤村健太、鬼頭浩史、大野欽司、今釜史郎
- Organizer
  第35回骨系統疾患研究会
- Data Source
  KAKENHI-PROJECT-22K09398
[Presentation] 軟骨無形成症患児を対象としたFGFR3シグナル抑制薬の14日間連続経口投与第1b相治験2023
- Author(s)
  松下雅樹、鬼頭浩史、三島健一、神谷庸成、加藤大策、竹本元太、澤村健太、今釜史郎
- Organizer
  第96回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-22K09398
[Presentation] 軟骨無形成症患児を対象としたFGFR3シグナル抑制薬の14日間連続経口投与第1b相治験2023
- Author(s)
  松下雅樹、鬼頭浩史、三島健一、神谷庸成、加藤大策、竹本元太、澤村健太、今釜史郎
- Organizer
  第96回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] 骨の形成、再生を制御する骨の幹細胞を探し求めて2023
- Author(s)
  松下祐樹
- Organizer
  第82回日本矯正歯科学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21487
[Presentation] メクロジンの経口投与は軟骨無形成症マウスモデルの脊柱管を拡大し麻痺の発生率を低減する2023
- Author(s)
  船橋洋人、松下雅樹、三島健一、神谷庸成、澤村健太、鬼頭浩史、大野欽司、今釜史郎
- Organizer
  第38回日本整形外科基礎学術集会
- Data Source
  KAKENHI-PROJECT-22K09398
[Presentation] 骨の起源の全貌解明と新規骨格幹細胞（骨内膜幹細胞）の同定2023
- Author(s)
  松下祐樹
- Organizer
  第23回日本再生医療学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21487
[Presentation] 骨系統疾患における診断遅延2023
- Author(s)
  三島　健一、神谷　庸成、澤村　健太、松下　雅樹、今釜　史郎
- Organizer
  第96回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-22K09304
[Presentation] 慢性再発性多発性骨髄炎の治療成績2023
- Author(s)
  三島　健一、神谷　庸成、澤村　健太、松下　雅樹、今釜　史郎
- Organizer
  第96回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09573
[Presentation] FGFR3シグナルは、若年マウスの阻血性骨壊死の骨修復を加速する2023
- Author(s)
  加藤大策、松下雅樹、竹上靖彦、三島健一、神谷宣広、大澤侑介、今釜史郎、鬼頭浩史
- Organizer
  第35回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-22K09398
[Presentation] 軟骨無形成症治療の現在と未来2023
- Author(s)
  松下雅樹
- Organizer
  第19回東海小児整形外科研修会
- Data Source
  KAKENHI-PROJECT-22K09398
[Presentation] FGFR3シグナルは若年マウスの阻血性骨壊死の骨修復を加速する2023
- Author(s)
  加藤大策、松下雅樹、竹上靖彦、三島健一、神谷宣広、大澤郁介、今釜史郎、鬼頭浩史
- Organizer
  第35回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-21H03063
[Presentation] The Amazing Endosteum2023
- Author(s)
  松下祐樹
- Organizer
  Japan Sweden Workshop on Cartilage, Bone and Bone marrow
- Invited
- Data Source
  KAKENHI-PROJECT-23K21487
[Presentation] Long-term administration of meclozine for the treatment of achondroplasia using a mouse model2023
- Author(s)
  Funahashi H, Matsushita M, Mishima K, Okawara B, Kamiya Y, Ohno K, Kitoh H, Imagama S
- Organizer
  Orthopaedic Research Society 2023 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03063
[Presentation] 骨系統疾患における診断遅延2023
- Author(s)
  三島　健一、神谷　庸成、澤村　健太、松下　雅樹、今釜　史郎
- Organizer
  第96回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09573
[Presentation] 骨の形成、再生、がんを制御する幹細胞を探し求めて2023
- Author(s)
  松下祐樹
- Organizer
  第65回歯科基礎医学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21487
[Presentation] 慢性再発性多発性骨髄炎の治療成績2023
- Author(s)
  三島　健一、神谷　庸成、澤村　健太、松下　雅樹、今釜　史郎
- Organizer
  第96回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-22K09304
[Presentation] 軟骨無形成症治療の現在と未来2023
- Author(s)
  松下雅樹
- Organizer
  第19回東海小児整形外科研修会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] Fgfr3-expressing endosteal stromal cells dictate active osteogenesis and aggressive tumorigenesis2023
- Author(s)
  Yuki Matsushita
- Organizer
  Japan Bone Academy 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21487
[Presentation] 新たな骨の幹細胞の発見　-骨格幹細胞からがん幹細胞への悪性形質転換-2023
- Author(s)
  松下祐樹
- Organizer
  第5回口腔医科学フロンティア
- Invited
- Data Source
  KAKENHI-PROJECT-23K21487
[Presentation] Bone marrow endosteal stem cells coordinate active osteogenesis and tumorigenesis in young bones2023
- Author(s)
  Yuki Matsushita
- Organizer
  The 71st Annual Meeting of Japanese Association for Dental Research
- Invited
- Data Source
  KAKENHI-PROJECT-23K21487
[Presentation] FGFR3シグナルは、若年マウスの阻血性骨壊死の骨修復を加速する2023
- Author(s)
  加藤大策、松下雅樹、竹上靖彦、三島健一、神谷宣広、大澤侑介、今釜史郎、鬼頭浩史
- Organizer
  第35回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] 脊柱管狭窄症とFGFR3異常症2023
- Author(s)
  松下雅樹、鬼頭浩史、三島健一、神谷庸成、澤村健太、今釜史郎
- Organizer
  第96回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-22K09398
[Presentation] 脊柱管狭窄症とFGFR3異常症2023
- Author(s)
  松下雅樹、鬼頭浩史、三島健一、神谷庸成、澤村健太、今釜史郎
- Organizer
  第96回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] 軟骨無形成症マウスモデルを用いたFGFR3インヒビターの大後頭孔と脊柱管に対する効果の検討2023
- Author(s)
  松下雅樹、船橋洋人、三島健一、神谷庸成、澤村健太、鬼頭浩史、大野欽司、今釜史郎
- Organizer
  第35回骨系統疾患研究会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] A 14-day repeated oral administration of meclizine in child patients with achondroplasia to evaluate safety and pharmacokinetics2023
- Author(s)
  Masaki Matsushita, Hiroshi Kitoh, Kenichi Mishima, Yasunari Kamiya, Kenta Sawamura, Kazuki Nishida, Yasuhiro Nakai, Shiro Imagama
- Organizer
  ASBMR 2023 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] エクソーム解析による骨系統疾患の遺伝学的診断2023
- Author(s)
  三島　健一、神谷　庸成、澤村　健太、松下　雅樹、加藤　耕治、荻　朋男、今釜　史郎、鬼頭　浩史
- Organizer
  第35回日本整形外科学会骨系統疾患研究会
- Data Source
  KAKENHI-PROJECT-22K09304
[Presentation] Long-term oral administration of meclozine for the treatment of achondroplasia using a mouse model2023
- Author(s)
  Funahashi H, Matsushita M, Mishima K, Okawara B, Kamiya Y, Ohno K, Kitoh H, Imagama S
- Organizer
  Orthopaedic Research Society 2023 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] メクロジンはMAPK経路を抑制しゼブラフィッシュ幼生のFgf2による骨形成を減弱する2022
- Author(s)
  竹本元大、松下雅樹、細野祥之、岡本喬明、鬼頭浩史、今釜史郎、大野欽司
- Organizer
  第34回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] Dobbs法による初期治療を行った先天性垂直距骨の治療経験2022
- Author(s)
  三島　健一、神谷　庸成、澤村　健太、松下　雅樹、今釜　史郎
- Organizer
  第33回日本小児整形外科学会
- Data Source
  KAKENHI-PROJECT-19K09573
[Presentation] 骨系統疾患の成人期における健康関連QOLの検討2022
- Author(s)
  松下雅樹、鬼頭浩史、三島健一、神谷庸成、芳賀信彦、藤原清香、大薗恵一、安心院朗子、今釜史郎
- Organizer
  第59回日本リハビリテーション医学会学術集会
- Data Source
  KAKENHI-PROJECT-22K09398
[Presentation] 4歳以降に診断された発育性股関節形成不全症3例に対するオーバーヘッド牽引法の短期治療成績2022
- Author(s)
  三島　健一、神谷　庸成、松下　雅樹、今釜　史郎
- Organizer
  第139回中部日本整形外科災害外科学会
- Data Source
  KAKENHI-PROJECT-19K09573
[Presentation] 軟骨無形成症患児を対象としたFGFR3シグナルを抑制する内服薬の14日間投与治験2022
- Author(s)
  松下雅樹、鬼頭浩史、三島健一、神谷庸成、澤村健太、今釜史郎
- Organizer
  第33回日本小児整形外科学会
- Data Source
  KAKENHI-PROJECT-21H03063
[Presentation] Dobbs法による初期治療を行った先天性垂直距骨の治療経験2022
- Author(s)
  三島　健一、神谷　庸成、澤村　健太、松下　雅樹、今釜　史郎
- Organizer
  第33回日本小児整形外科学会
- Data Source
  KAKENHI-PROJECT-22K09304
[Presentation] 骨系統疾患の成人期における健康関連QOLの検討2022
- Author(s)
  松下雅樹、鬼頭浩史、三島健一、神谷庸成、芳賀信彦、藤原清香、大薗恵一、安心院朗子、今釜史郎
- Organizer
  第59回日本リハビリテーション医学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] 軟骨無形成症患児を対象としたFGFR3シグナル抑制薬投与第1相治験2022
- Author(s)
  松下雅樹、三島健一、神谷庸成、加藤大策、竹本元大、今釜史郎、鬼頭浩史
- Organizer
  第95回日本整形外科学会
- Data Source
  KAKENHI-PROJECT-21H03063
[Presentation] Abnormal growth plate structure in mouse model of hypophosphatemic rickets is ameliorated by meclozine treatment2022
- Author(s)
  Y Kamiya, M Matsushita, K Mishima, B Ohkawara, S Imagma, K Ohno, H Kitoh
- Organizer
  Orthopaedic Research Society 2022 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] 軟骨無形成症患児を対象としたFGFR3シグナル抑制薬投与第1相治験2022
- Author(s)
  松下雅樹、三島健一、神谷庸成、加藤大策、竹本元太、今釜史郎、鬼頭浩史
- Organizer
  第95回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] 4歳以降に診断された発育性股関節形成不全症3例に対するオーバーヘッド牽引法の短期治療成績2022
- Author(s)
  三島　健一、神谷　庸成、松下　雅樹、今釜　史郎
- Organizer
  第139回中部日本整形外科災害外科学会
- Data Source
  KAKENHI-PROJECT-22K09304
[Presentation] 軟骨無形成症患児を対象としたFGFR3シグナル抑制薬投与第1相治験2022
- Author(s)
  松下雅樹、三島健一、神谷庸成、加藤大策、竹本元太、今釜史郎、鬼頭浩史
- Organizer
  第95回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-22K09398
[Presentation] Abnormal growth plate structure in mouse model of hypophosphatemic rickets is ameliorated by meclozine treatment2022
- Author(s)
  Yasunari Kamiya, Masaki Matsushita, Kenichi Mishima, Bisei Ohkawara, Shiro Imagma, Kinji Ohno, Hiroshi Kitoh
- Organizer
  Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09477
[Presentation] Health-related quality of life in patients with multiple epiphyseal dysplasia and spondyloepiphyseal dysplasia.2021
- Author(s)
  Matsushita M, Mishima K, Kamiya Y, Haga N, Fujiwara S, Ozono K, Kubota T, KItaoka T, Imagama S, Kitoh H
- Organizer
  13th Combined Meeting of Asia Pacific Spine Society & Asia Pacific Paediatric Orthopaedic Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03063
[Presentation] ドラッグリポジショニングによる軟骨無形成症に対する治療薬開発2021
- Author(s)
  鬼頭浩史、松下雅樹、三島健一、神谷庸成、金子浩史、北村暁子、澤村健太
- Organizer
  第39回日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] メクロジンはゼブラフィッシュの骨格形成期においてFgf2による骨化促進作用を抑制する2021
- Author(s)
  竹本元大、松下雅樹、細野祥之、岡本喬明、今釜史郎、大野欽司
- Organizer
  第36回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] 若年に変形性関節症発症リスクが高い骨系統疾患の成人期のQOLの検討2021
- Author(s)
  松下雅樹、三島健一、長田侃、神谷庸成、芳賀信彦、藤原清香、大薗恵一、窪田拓生、北岡太一、今釜史郎、鬼頭浩史
- Organizer
  第94回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] ソルター骨盤骨切り術によるペルテス病分節期の短縮効果2021
- Author(s)
  三島　健一、神谷　庸成、松下　雅樹、今釜　史郎
- Organizer
  第32回日本小児整形外科学会
- Data Source
  KAKENHI-PROJECT-19K09573
[Presentation] 骨端異形成を伴う骨系統疾患の成人期のQoLの検討2021
- Author(s)
  松下雅樹、三島健一、神谷庸成、芳賀信彦、藤原清香、大薗恵一、今釜史郎、鬼頭浩史
- Organizer
  第32回日本小児整形外科学会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] 小児難治性運動器疾患に対する薬物アプローチ.2021
- Author(s)
  鬼頭浩史、三島健一、松下雅樹、神谷庸成、金子浩史、北村暁子、澤村健太
- Organizer
  第36回日本整形外科学会基礎学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H03063
[Presentation] The role of the Salter innominate osteotomy in Legg-Calve-Perthes disease.2021
- Author(s)
  Mishima K, Kaneko H, Matsushita M, Kamiya Y, Imagama S, Kitoh H
- Organizer
  13th Combined Meeting of Asia Pacific Spine Society & Asia Pacific Paediatric Orthopaedic Society.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03063
[Presentation] Salter-Harris分類V型の骨端線損傷による外反膝変形をTL-HEXシステムで矯正した１例2021
- Author(s)
  三島　健一、神谷　庸成、松下　雅樹、今釜　史郎
- Organizer
  第136回中部日本整形外科災害外科学会
- Data Source
  KAKENHI-PROJECT-19K09573
[Presentation] Health-related quality of life in patients with multiple epiphyseal dysplasia and spondyloepiphyseal dysplasia2021
- Author(s)
  M Matsushita, K Mishima, Y Kamiya, N Haga, S Fujiwara, K Ozono, T Kubota, T Kitaoka, S Imagama, H Kitoh
- Organizer
  13th Combined Meeting of Asia Pacific Spine Society & Asia Pacific Paediatric Orthopaedic Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] Meclozineは低リン血症性くる病マウスモデルの表現型をレスキューする2021
- Author(s)
  神谷庸成、松下雅樹、三島健一、長田侃、石黒直樹、大野欽司、鬼頭浩史
- Organizer
  第33回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] The role of the Salter innominate osteotomy in Legg-Calve-Perthes disease.2021
- Author(s)
  Mishima K, Kaneko H, Matsushita M, Kamiya Y, Imagama S, Kitoh H.
- Organizer
  APSS-APPOS 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09573
[Presentation] 思春期以降の軟骨無形成症患者が困っていることと工夫していること2021
- Author(s)
  松下雅樹、三島健一、長田侃、神谷庸成、安心院朗子、芳賀信彦、藤原清香、大薗恵一、今釜史郎、鬼頭浩史
- Organizer
  第94回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] エイトプレートによる脚長不等の治療成績-特発性片側肥大症を対象とした検討-2021
- Author(s)
  三島　健一、神谷　庸成、松下　雅樹、今釜　史郎
- Organizer
  第32回日本小児整形外科学会
- Data Source
  KAKENHI-PROJECT-19K09573
[Presentation] Guided growth: Approach for skeletal dysplasia.2021
- Author(s)
  Kitoh H, Kaneko H, Mishima K, Matsushita M, Kitamura A, Kamiya Y, Sawamura S
- Organizer
  13th Combined Meeting of Asia Pacific Spine Society & Asia Pacific Paediatric Orthopaedic Society.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03063
[Presentation] 発症後早期に施行したSalter 骨盤骨切り術によってPerthes 病の分節期は短縮するのか？2021
- Author(s)
  三島　健一、神谷　庸成、松下　雅樹、今釜　史郎
- Organizer
  第94回日本整形外科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09573
[Presentation] Efficacy and tolerability of meclozine for the treatment of short stature in a mouse model of achondroplasia2021
- Author(s)
  Masaki Matsushita, Kenichi Mishima, Tadashi Nagata, Yasunari Kamiya, Shiro Imagama, Kinji Ohno, Hiroshi Kitoh
- Organizer
  Orthopaedic Research Society 2021 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] ドラッグリポジショニングによる軟骨無形成症に対する治療薬開発.2021
- Author(s)
  鬼頭浩史、松下雅樹、三島健一、神谷庸成、金子浩史、北村暁子、澤村健太
- Organizer
  第39回日本骨代謝学会
- Invited
- Data Source
  KAKENHI-PROJECT-21H03063
[Presentation] 軟骨無形成症マウスモデルを用いたmeclozineの至適投与量の精査2021
- Author(s)
  松下雅樹、三島健一、長田侃、神谷庸成、石黒直樹、大野欽司、鬼頭浩史
- Organizer
  第33回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] Efficacy of soluble lansoprazole-impregnated artificial bones for repairing cortical bone defects in rabbits2020
- Author(s)
  Kenichi Mishima, Ryusaku Esaki, Masaki Matsushita, Naoki Ishiguro.
- Organizer
  2020 Orthopaedic Research Society (ORS) Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09573
[Presentation] Perthes病を発症したBardet-Biedl症候群の1例2020
- Author(s)
  三島　健一、神谷　庸成、長田　侃、松下　雅樹、今釜　史郎、鬼頭　浩史
- Organizer
  第32回日本整形外科学会骨系統疾患研究会
- Data Source
  KAKENHI-PROJECT-19K09573
[Presentation] 慢性再発性多発性骨髄炎 (CRMO)７例の治療成績2020
- Author(s)
  三島　健一、神谷　庸成、長田　侃、松下　雅樹、今釜　史郎
- Organizer
  第31回日本小児整形外科学会
- Data Source
  KAKENHI-PROJECT-19K09573
[Presentation] 軟骨無形成症マウスモデルにおける骨膜剥離による骨伸長効果の検討2020
- Author(s)
  金子慎哉、松下雅樹、三島健一、竹上靖彦、石黒直樹、鬼頭浩史
- Organizer
  第35回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] Periosteal resection promotes longitudinal bone growth via activating endochondral ossification in growing mouse model2020
- Author(s)
  Shinya Kaneko, Masaki Matsushita, Kenichi Mishima, Hiroshi Kitoh, Naoki Ishiguro
- Organizer
  Orthopaedic Research Society 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] Local administration of meclozine promotes the longitudinal growth of selected bone in mouse model2020
- Author(s)
  Tadashi Nagata, Masaki Matsushita, Kenichi Mishima, Yasunari Kamiya, Bisei Ohkawara, Kinji Ohno, Naoki Ishiguro, Hiroshi Kitoh
- Organizer
  Orthopaedic Research Society 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] Effect of periosteal resection on longitudinal bone growth in a mouse model of achondroplasia2020
- Author(s)
  Shinya Kaneko, Masaki Matsushita, Kenichi Mishima, Yasuhiko Takegami, Shiro Imagama, Hiroshi Kitoh
- Organizer
  第31回日本小児整形外科学会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] FGFR3シグナル抑制薬meclozineの軟骨無形成症に対する治療法の実用化に向けて2020
- Author(s)
  松下雅樹、三島健一、長田侃、神谷庸成、今釜史郎、大野欽司、鬼頭浩史
- Organizer
  第31回日本小児整形外科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] Meclozineは軟骨無形成症と低リン血症性くる病マウスモデルの表現型をレスキューする2020
- Author(s)
  神谷庸成、松下雅樹、三島健一、長田侃、石黒直樹、大河原美静、大野欽司、鬼頭浩史
- Organizer
  第35回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] Meclozine promotes bone growth and bone mineralization in mouse model of hypophosphatemic rickets2020
- Author(s)
  Yasunari Kamiya, Masaki Matsushita, Kenichi Mishima, Tadashi Nagata, Naoki Ishiguro, Kinji Ono, Hiroshi Kitoh
- Organizer
  Orthopaedic Research Society 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] 成人期軟骨無形成症患者が在宅生活内で困っていることと工夫していること2020
- Author(s)
  安心院郎子、松下雅樹、三島健一、鬼頭浩史
- Organizer
  第31回日本小児整形外科学会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] ペルテス病に対するソルター骨盤骨切り術の治療成績 ―骨頭前方の骨吸収パターンの違いによる予後予測－2019
- Author(s)
  三島　健一、鬼頭　浩史、松下　雅樹、門野　泉、長田　侃、神谷　庸成、石黒　直樹
- Organizer
  第92回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-16K10854
[Presentation] ペルテス病における血液検査所見と予後因子との関連2019
- Author(s)
  三島　健一、神谷　庸成、長田　侃、松下　雅樹、石黒　直樹
- Organizer
  第30回日本小児整形外科学会
- Data Source
  KAKENHI-PROJECT-16K10854
[Presentation] Drug repositioning for FGF23-mediated hypophosphatemia: Disulfiram lowers FGF23 production2019
- Author(s)
  Mishima K, Sugiura H, Esaki R, Matsushita M, Kitoh H, Ishiguro N, Ohno K.
- Organizer
  2019 Orthopaedic Research Society (ORS) Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10854
[Presentation] 特発性先天性内反足に対するPonseti法の長期成績（10年以上）と再発予測因子2019
- Author(s)
  三島　健一、鬼頭　浩史、松下　雅樹、石黒　直樹
- Organizer
  第92回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-16K10854
[Presentation] ペルテス病に対するソルター骨盤骨切り術の治療成績 ―骨頭前方の骨吸収パターンの違いによる予後予測－2019
- Author(s)
  三島　健一、鬼頭　浩史、松下　雅樹、門野　泉、長田　侃、神谷　庸成、石黒　直樹
- Organizer
  第92回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09573
[Presentation] Current techniques to prevent avascular necrosis in unstable slipped capital femoral epiphysis2019
- Author(s)
  Hiroshi Kitoh, Tadashi Hattori, Masaki Matsushita, Kenichi Mishima
- Organizer
  12th Combined Meeting of Asia Pacific Spine Society & Asia Pacific Paediatric Orthopaedic Society
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04312
[Presentation] 特発性先天性内反足に対するPonseti法の長期成績（10年以上）と再発予測因子2019
- Author(s)
  三島　健一、鬼頭　浩史、松下　雅樹、石黒　直樹
- Organizer
  第92回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09573
[Presentation] Meclozine increased bone mineralization and bone growth in mouse model of hypophosphatemic rickets2019
- Author(s)
  Yasunari Kamiya, Masaki Matsushita, Kenichi Mishima, Tadashi Nagata, Naoki Ishiguro, Kinji Ono, Hiroshi Kitoh
- Organizer
  第30回日本小児整形外科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] Ponseti法実施例の学童期における治療成績と患者立脚型評価2019
- Author(s)
  三島　健一、神谷　庸成、長田　侃、松下　雅樹、石黒　直樹　澤村　健太、北村　暁子、岩田　浩志、金子　浩史、鬼頭　浩史、服部　義
- Organizer
  第30回日本小児整形外科学会
- Data Source
  KAKENHI-PROJECT-16K10854
[Presentation] Drug repositioning for FGF23-mediated hypophosphatemia: Disulfiram lowers FGF23 production2019
- Author(s)
  Mishima K, Sugiura H, Esaki R, Matsushita M, Kitoh H, Ishiguro N, Ohno K
- Organizer
  2019 Orthopaedic Research Society (ORS) Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09573
[Presentation] 軟骨無形成症治療薬の開発―医師主導治験の実施―2019
- Author(s)
  鬼頭浩史、松下雅樹、三島健一、長田侃、神谷庸成
- Organizer
  第30回日本小児整形外科学会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04312
[Presentation] 軟骨無形成症治療薬の開発―医師主導治験の実施―2019
- Author(s)
  鬼頭浩史、松下雅樹、三島健一、長田侃、神谷庸成
- Organizer
  第30回日本小児整形外科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] Ponseti法実施例の学童期における治療成績と患者立脚型評価2019
- Author(s)
  三島　健一、神谷　庸成、長田　侃、松下　雅樹、石黒　直樹　澤村　健太、北村　暁子、岩田　浩志、金子　浩史、鬼頭　浩史、服部義
- Organizer
  第30回日本小児整形外科学会
- Data Source
  KAKENHI-PROJECT-19K09573
[Presentation] ペルテス病における血液検査所見と予後因子との関連2019
- Author(s)
  三島　健一、神谷　庸成、長田　侃、松下　雅樹、石黒　直樹
- Organizer
  第30回日本小児整形外科学会
- Data Source
  KAKENHI-PROJECT-19K09573
[Presentation] 骨系統疾患における成人期以降の問題点2019
- Author(s)
  鬼頭浩史、三島健一、松下雅樹、長田侃、神谷庸成、石黒直樹
- Organizer
  第92回日本整形外科学会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04312
[Presentation] 軟骨無形成症マウスモデルにおけるmeclozineの有効性と毒性の検討2019
- Author(s)
  松下雅樹、鬼頭浩史、三島健一、長田侃、神谷庸成、石黒直樹、大野欽司
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] 成人期の軟骨無（低）形成症患者が日常生活で困っていること2019
- Author(s)
  安心院朗子、松下雅樹、三島健一、石黒直樹、芳賀信彦、藤原清香、大薗恵一、鬼頭浩史
- Organizer
  第30回日本小児整形外科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09646
[Presentation] Drug repositioning for FGF23-mediated hypophosphatemia: Disulfiram lowers FGF23 production2019
- Author(s)
  Mishima K, Sugiura H, Esaki R, Matsushita M, Kitoh H, Ishiguro N, Ohno K
- Organizer
  2019 Orthopaedic Research Society (ORS) Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10854
[Presentation] Bone formation was promoted in mouse model of distraction osteogenesis with gain-of-function mutation in FGFR32018
- Author(s)
  Masaki Matsushita, Yusuke Ohsawa, Kenichi Mishima, Naoki Ishiguro, Kinji Ohno, Hiroshi Kitoh
- Organizer
  Fibroblast Growth Factors in Development and Disease Gordon Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10439
[Presentation] Bone formation was promoted in mouse model of distraction osteogenesis with gain-of-function mutations in Fgfr32018
- Author(s)
  Yusuke Osawa, Masaki Matsushita, Kenichi Mishima, Naoki Ishiguro, Kinji Ohno, Hiroshi Kitoh
- Organizer
  Annual meeting of Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04312
[Presentation] エイトプレートによる大転子骨端線抑制術の短期治療成績2018
- Author(s)
  三島　健一、鬼頭　浩史、松下　雅樹、門野　泉、長田　侃、西田　佳弘、石黒　直樹
- Organizer
  第33回東海小児整形外科懇話会
- Data Source
  KAKENHI-PROJECT-16K10854
[Presentation] エイトプレートによる大転子骨端線抑制術の治療成績2018
- Author(s)
  三島　健一、鬼頭　浩史、松下　雅樹、門野　泉、長田　侃、神谷　庸成、石黒　直樹
- Organizer
  第29回日本小児整形外科学会
- Data Source
  KAKENHI-PROJECT-16K10854
[Presentation] Bone formation was promoted in mouse model of distraction osteogenesis with gain-of-function mutations in Fgfr32018
- Author(s)
  Yusuke Osawa, Masaki Matsushita, Kenichi Mishima, Naoki Ishiguro, Kinji Ohno, Hiroshi Kitoh
- Organizer
  Annual meeting of Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] Bone formation was promoted in mouse model of distraction osteogenesis with gain-of-function mutations in Fgfr32018
- Author(s)
  Osawa Y, Matsushita M, Mishima K, Ishiguro N, Ohno K, Kitoh H
- Organizer
  Annual meeting of Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04312
[Presentation] Long-term health-related quality of life in patients with achondroplasia and hypochondroplasia2018
- Author(s)
  11.Matsushita M, Kitoh H, Mishima K, Ishiguro N, Fujiwara S, Haga N, Kitaoka T, Kubota T, Ozono K
- Organizer
  Annual meeting of the American Society for Bone and Mineral Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04312
[Presentation] ペルテス病に対するソルター骨盤骨切り術の治療成績 ―骨頭前方の骨吸収パターンの違いによる予後予測－2018
- Author(s)
  三島　健一、鬼頭　浩史、松下　雅樹、門野　泉、長田　侃、神谷　庸成、石黒　直樹
- Organizer
  第29回日本小児整形外科学会
- Data Source
  KAKENHI-PROJECT-16K10854
[Presentation] Activated FGFR3 prevents subchondral bone sclerosis during the development of osteoarthritis in transgenic mice with achondroplasia2017
- Author(s)
  Toshiaki Okura, Masaki Matsushita, Kenichi Mishima, Ryusaku Esaki, Taisuke Seki, Naoki Ishiguro, Hiroshi Kitoh
- Organizer
  The 27th Korean-Japanese Combined Orthopaedic Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04312
[Presentation] Long term health-related quality of life in achonroplasia2017
- Author(s)
  Masaki Matsushita, Hiroshi Kitoh, Kenichi Mishima, Satoshi Yamashita, Hiroshi Sugiura, Akiko Kitamura, Naoki Ishiguro
- Organizer
  EPOS/POSNA combined annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04312
[Presentation] Clinical feasibility of meclozine for improvement of short stature in achondroplasia2017
- Author(s)
  Masaki Matsushita, Hiroshi Kitoh, Kenichi Mishima, Hiroshi Sugiura, Akiko Kitamura, Naoki Ishiguro
- Organizer
  EPOS/POSNA combined annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04312
[Presentation] Activated FGFR3 promotes bone formation via accelerating endochondral ossification in mouse model of distraction osteogenesis2017
- Author(s)
  Yusuke Osawa, Masaki Matsushita, Naoki Ishiguro, Kinji Ohno, Hiroshi Kitoh
- Organizer
  The 27th Korean-Japanese Combined Orthopaedic Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04312
[Presentation] Clinically feasible dose of meclozine improves bone growth, bone volume, and bone quality in mouse model with achondroplasia2017
- Author(s)
  Masaki Matsushita, Kenichi Mishima, Naoki Ishiguro, Kinji Ohno, Hiroshi Kitoh
- Organizer
  The 27th Korean-Japanese Combined Orthopaedic Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04312
[Presentation] Clinically Feasible Dose of Meclozine Improves Bone Growth, Bone Volume, and Bone Quality in Mouse Model with Achondroplasia2017
- Author(s)
  Masaki Matsushita, Kenichi Mishima, Naoki Ishiguro, Kinji Ohno, Hiroshi Kitoh
- Organizer
  The 27th Korean-Japanese Combined Orthopaedic Symposium 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10439
[Presentation] Clinically feasible dose of meclozine improves bone growth, bone volume, and bone quality in mouse model with achondroplasia2017
- Author(s)
  Masaki Matsushita, Kenichi Mishima, Naoki Ishiguro, Kinji Ohno, Hiroshi Kitoh
- Organizer
  The 27th Korean-Japanese Combined Orthopaedic Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] Activated FGFR3 prevents subchondral bone sclerosis during the development of osteoarthritis in transgenic mice with achondroplasia2017
- Author(s)
  Toshiaki Okura, Masaki Matsushita, Kenichi Mishima, Ryusaku Esaki, Taisuke Seki, Naoki Ishiguro, Hiroshi Kitoh
- Organizer
  The 27th Korean-Japanese Combined Orthopaedic Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] Oral administration of meclozine for the treatment of short stature in achondroplasia2017
- Author(s)
  Hiroshi Kitoh, Masaki Matsushita, Kenichi Mishima, Naoki Ishiguro, Kinji Ohno
- Organizer
  The 13th International Skeletal Dysplasia Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] Transplantation of autologous culture-expanded bone marrow cells and platelet rich plasma for bone regeneration. Comprehensive clinical study of the lower limb lengthening2017
- Author(s)
  Hiroshi Kitoh, Kenichi Mishima, Masaki Matsushita, Hiroshi Sugiura, Akiko Kitamura, Naoki Ishiguro
- Organizer
  EPOS/POSNA combined annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04312
[Presentation] Secondary spherical remodeling from the healed stage to skeletal maturity in Legg-Calve-Perthes Disease treated with Salter innominate osteotomy2017
- Author(s)
  Hiroshi Kaneko, Hiroshi Kitoh, Masaki Matsushita, Hiroki Furuhashi, Tadashi Hattori
- Organizer
  EPOS/POSNA combined annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] Transplantation of autologous culture-expanded bone marrow cells and platelet rich plasma for bone regeneration. Comprehensive clinical study of the lower limb lengthening2017
- Author(s)
  Hiroshi Kitoh, Kenichi Mishima, Masaki Matsushita, Hiroshi Sugiura, Akiko Kitamura, Naoki Ishiguro
- Organizer
  EPOS/POSNA combined annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] Clinical feasibility of meclozine for improvement of short stature in achondroplasia2017
- Author(s)
  Masaki Matsushita, Hiroshi Kitoh, Kenichi Mishima, Hiroshi Sugiura, Akiko Kitamura, Naoki Ishiguro
- Organizer
  EPOS/POSNA combined annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] 骨髄間葉系幹細胞とPRPを用いた骨延長術2017
- Author(s)
  鬼頭浩史、三島健一、松下雅樹、石黒直樹
- Organizer
  第2回JAPSAM幹細胞研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04312
[Presentation] Activated FGFR3 prevents subchondral bone sclerosis during the development of osteoarthritis in transgenic mice with achondroplasia2017
- Author(s)
  Toshiaki Okura, Masaki Matsushita, Kenichi Mishima, Ryusaku Esaki, Taisuke Seki, Naoki Ishiguro, Hiroshi Kitoh
- Organizer
  Annual meeting of the American Society for Bone and Mineral Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10439
[Presentation] Treatment of deformities in lower extremity by a multi-axial external fixation system2017
- Author(s)
  Masaki Matsushita, Hiroshi Kitoh, Kenichi Mishima, Naoki Ishiguro
- Organizer
  The 61st Korean Orthopaedic Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] 先天性垂直距骨に対するDobbs法の短期治療成績2017
- Author(s)
  三島　健一、鬼頭　浩史、松下　雅樹、門野　泉、杉浦　洋、北村　暁子、西田　佳弘、石黒　直樹
- Organizer
  第32回東海小児整形外科懇話会
- Data Source
  KAKENHI-PROJECT-16K10854
[Presentation] Treatment of deformities in lower extremity by a multi-axial external fixation system2017
- Author(s)
  Masaki Matsushita, Hiroshi Kitoh, Kenichi Mishima, Naoki Ishiguro
- Organizer
  The 61st Korean Orthopaedic Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04312
[Presentation] Disappearance of soft tissue interposition after gradual reduction using overhead traction in late-presenting DDH. A prospective comparative study on serial MRIs between pre-walking and walking children2017
- Author(s)
  Hiroshi Kaneko, Tadashi Hattori, Koji Iwata, Masaki Matsushita, Hiroki Furuhashi, Hiroshi Kitoh
- Organizer
  EPOS/POSNA combined annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04312
[Presentation] Disappearance of soft tissue interposition after gradual reduction using overhead traction in late-presenting DDH. A prospective comparative study on serial MRIs between pre-walking and walking children2017
- Author(s)
  Hiroshi Kaneko, Tadashi Hattori, Koji Iwata, Masaki Matsushita, Hiroki Furuhashi, Hiroshi Kitoh
- Organizer
  EPOS/POSNA combined annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] 脚長差に伴う機能性側弯の特徴2017
- Author(s)
  三島　健一、鬼頭　浩史、松下　雅樹、門野　泉、長田　侃、西田　佳弘、石黒　直樹
- Organizer
  第28回日本小児整形外科学会
- Data Source
  KAKENHI-PROJECT-16K10854
[Presentation] 軟骨無形成症の根本的治療を目指したmeclozineの有効投与量の検討2017
- Author(s)
  松下雅樹、鬼頭浩史、三島健一、杉浦　洋、北村　暁子、西田佳弘、石黒直樹、大野欽司
- Organizer
  第30回日本軟骨代謝学会
- Place of Presentation
  京都市勧業館みやこめっせ（京都府京都市）
- Year and Date
  2017-03-03
- Data Source
  KAKENHI-PROJECT-15K10439
[Presentation] Oral administration of meclozine for the treatment of short stature in achondroplasia2017
- Author(s)
  Hiroshi Kitoh, Masaki Matsushita, Kenichi Mishima, Naoki Ishiguro, Kinji Ohno
- Organizer
  The 13th International Skeletal Dysplasia Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04312
[Presentation] Transplantation of autologous culture-expanded bone marrow cells and platelet rich plasma during lower limb lengthening2017
- Author(s)
  Hiroshi Kitoh, Kenichi Mishima, Masaki Matsushita, Naoki Ishiguro
- Organizer
  The 27th Korean-Japanese Combined Orthopaedic Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04312
[Presentation] Clinically feasible dose of meclozine promotes bone growth in mouse model with achondroplasia2017
- Author(s)
  Masaki Matsushita, Hiroshi Kitoh, Kenichi Mishima, Hiroshi Sugiura, Sachi Hasegawa, Akiko Kitamura, Naoki Ishiguro, Kinji Ohno
- Organizer
  Annual Meeting - Orthopaedic Research Society (ORS)
- Place of Presentation
  San Diego （ＵＳＡ）
- Year and Date
  2017-03-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10439
[Presentation] Secondary spherical remodeling from the healed stage to skeletal maturity in Legg-Calve-Perthes Disease treated with Salter innominate osteotomy2017
- Author(s)
  Hiroshi Kaneko, Hiroshi Kitoh, Masaki Matsushita, Hiroki Furuhashi, Tadashi Hattori
- Organizer
  EPOS/POSNA combined annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04312
[Presentation] Transplantation of autologous culture-expanded bone marrow cells and platelet rich plasma during lower limb lengthening2017
- Author(s)
  Hiroshi Kitoh, Kenichi Mishima, Masaki Matsushita, Naoki Ishiguro
- Organizer
  The 27th Korean-Japanese Combined Orthopaedic Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] Long term health-related quality of life in achonroplasia2017
- Author(s)
  Masaki Matsushita, Hiroshi Kitoh, Kenichi Mishima, Satoshi Yamashita, Hiroshi Sugiura, Akiko Kitamura, Naoki Ishiguro
- Organizer
  EPOS/POSNA combined annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] Activated FGFR3 promotes bone formation via accelerating endochondral ossification in mouse model of distraction osteogenesis2017
- Author(s)
  Yusuke Osawa, Masaki Matsushita, Naoki Ishiguro, Kinji Ohno, Hiroshi Kitoh
- Organizer
  The 27th Korean-Japanese Combined Orthopaedic Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] 骨髄間葉系幹細胞とPRPを用いた骨延長術2017
- Author(s)
  鬼頭浩史、三島健一、松下雅樹、石黒直樹
- Organizer
  第2回JAPSAM幹細胞研究会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] Clinical feasibility of meclozine for improvement of short stature in achondroplasia2017
- Author(s)
  Masaki Matsushita, Hiroshi Kitoh, Kenichi Mishima, Hiroshi Sugiura, Akiko Kitamura, Naoki Ishiguro
- Organizer
  2017 Combined European Pediatric Orthopaedic Society/Pediatric Orthopaedic Society of North America (EPOSNA) Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10439
[Presentation] Meclozine投与による軟骨無形成症モデルマウスにおける骨伸張と骨質の検討2017
- Author(s)
  松下雅樹、鬼頭浩史、三島健一、北村　暁子、長田　侃、西田佳弘、石黒直樹、大野欽司
- Organizer
  第32回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-15K10439
[Presentation] Meclozine投与による軟骨無形成症モデルマウスにおける骨伸張と骨質の検討2017
- Author(s)
  松下雅樹、鬼頭浩史、三島健一、北村　暁子、長田　侃、西田佳弘、石黒直樹、大野欽司
- Organizer
  第35回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-15K10439
[Presentation] 軟骨無形成症に対する根本的治療の開発2016
- Author(s)
  松下雅樹、鬼頭浩史、三島健一、杉浦　洋、長谷川　幸、北村　暁子、石黒直樹、大野欽司
- Organizer
  第27回日本小児整形外科学会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-15K10439
[Presentation] Clinically attainable concentration of meclozine has a potent effect on promoting bone growth in achondroplasia2016
- Author(s)
  Masaki Matsushita, Hiroshi Kitoh, Kenichi Mishima, Naoki Ishiguro, Kinji Ohno
- Organizer
  The annual scientific meeting of the endocrine society of Australia, the Society for Reproductive Biology and the Australia and New Zealand Bone and Mineral Society
- Place of Presentation
  Gold Coast （Australia）
- Year and Date
  2016-08-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] Genu varum in achondroplasia and hypochondroplasia2016
- Author(s)
  Hiroshi Kitoh, Kenichi Mishima, Masaki Matsushita. Hiroshi Sugiura, Sachi Hasegawa, Naoki Ishiguro
- Organizer
  Annual meeting of Pediatric Orthopedic Society of North America
- Place of Presentation
  Indianapolis （ＵＳＡ）
- Year and Date
  2016-04-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] 軟骨無形成症治療の現在と未来2016
- Author(s)
  松下雅樹
- Organizer
  つくしんぼ総会
- Place of Presentation
  大阪市長居障がい者スポーツセンター（大阪府大阪市）
- Invited
- Data Source
  KAKENHI-PROJECT-15K10439
[Presentation] ランソプラゾールによる骨芽細胞・破骨細胞分化促進効果と分子作用機序の解析2016
- Author(s)
  三島健一、鬼頭浩史、岡部由香、松下雅樹、西田佳弘、石黒直樹、大野欽司
- Organizer
  第34回日本骨代謝学会・第3回アジア太平洋骨代謝学会
- Place of Presentation
  大阪国際会議場（大阪市北区）
- Year and Date
  2016-07-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] Clinically attainable concentration of meclozine promotes bone growth in transgenic mice with achondroplasia2016
- Author(s)
  Matsushita M, Kitoh H, Mishima K, Nishida Y, Ishiguro N, Ohno K
- Organizer
  Gordon Research Conference
- Place of Presentation
  Hong Kong （China）
- Year and Date
  2016-06-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] Clinically attainable concentration of meclozine has a potent effect on promoting bone growth in achondroplasia2016
- Author(s)
  Masaki Matsushita, Hiroshi Kitoh, Kenichi Mishima, Naoki Ishiguro, Kinji Ohno
- Organizer
  Annual Meetings of the Endocrine Society of Australia and Society for Reproductive Biology and Australia and New Zealand Bone and Mineral Society
- Place of Presentation
  Gold Coast （Australia）
- Year and Date
  2016-08-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10439
[Presentation] Clinical feasibility of oral administration of meclozine for the treatment of short stature in achondroplasia2016
- Author(s)
  Masaki Matsushita, Hiroshi Kitoh, Kenichi Mishima, Naoki Ishiguro, Kinji Ohno
- Organizer
  American Society for Bone and Mineral Research (ASBMR) Annual Meeting
- Place of Presentation
  Atlanta（ＵＳＡ）
- Year and Date
  2016-09-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10439
[Presentation] FGFR3-targetted therapy for short stature in achondroplasia2016
- Author(s)
  Hiroshi Kitoh, Masaki Matsushita, Kenichi Mishima, Naoki Ishiguro
- Organizer
  60th Korean Orthopaedic Association
- Place of Presentation
  Incheon （Korea）
- Year and Date
  2016-10-19
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] Clinically attainable concentration of meclozine promotes bone growth in transgenic mice with achondroplasia2016
- Author(s)
  Masaki Matsushita, Hiroshi Kitoh, Kenichi Mishima, Naoki Ishiguro, Kinji Ohno
- Organizer
  Fibroblast Growth Factors in Development & Disease - Gordon Research Conference
- Place of Presentation
  Hong Kong （China）
- Year and Date
  2016-06-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10439
[Presentation] Treatment strategies for short stature in achondroplasia2016
- Author(s)
  Hiroshi Kitoh, Kenichi Mishima, Masaki Matsushita
- Organizer
  13th International Congress of Human Genetics
- Place of Presentation
  国立京都国際会館（京都市左京区）
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] meclozineによる軟骨無形成症の根本的治療の可能性と限界2016
- Author(s)
  松下雅樹、鬼頭浩史、三島健一、杉浦　洋、西田佳弘、石黒直樹、大野欽司
- Organizer
  第34回日本骨代謝学会学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-15K10439
[Presentation] Early radiographic parameters predictive of surgery-required relapse in idiopathic clubfoot treated using the Ponseti method.2016
- Author(s)
  Mishima K, Kitoh H, Matsushita M, Sugiura H, Ishiguro N.
- Organizer
  37th SICOT Orthopaedic World Congress
- Place of Presentation
  ローマ（イタリア）
- Year and Date
  2016-09-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10854
[Presentation] 原因不明の若年性変形性股関節症に対してソルター骨盤骨切り術と大腿骨内反骨切り術を実施した1例2016
- Author(s)
  三島健一、鬼頭浩史、松下雅樹, 杉浦　洋、長谷川幸, 北村暁子、西田　佳弘、石黒　直樹
- Organizer
  第55回日本小児股関節研究会
- Place of Presentation
  さん太ホール（岡山県岡山市）
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-16K10854
[Presentation] MeclozineはFGFR3シグナルを抑制し軟骨無形成症における低身長を改善しうる2016
- Author(s)
  松下雅樹、鬼頭浩史、三島健一、西田佳弘、石黒直樹、大野欽司
- Organizer
  第29回日本軟骨代謝学会
- Place of Presentation
  広島大学広仁会館（広島県広島市）
- Year and Date
  2016-02-19
- Data Source
  KAKENHI-PROJECT-15K10439
[Presentation] meclozineは乗り物酔い止め薬としての効能を発揮する用量の連日投与により軟骨無形成症における骨伸張を促進しうる2016
- Author(s)
  松下雅樹、鬼頭浩史、三島健一、杉浦　洋、西田佳弘、石黒直樹、大野欽司
- Organizer
  第31回日本整形外科学会基礎学術集会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K10439
[Presentation] Radical therapeutic strategy for foramen magnum stenosis and spinal canal stenosis in achondroplasia2016
- Author(s)
  Masaki Matsushita, Hiroshi Kitoh, Kenichi Mishima, Hiroshi Sugiura, Sachi Hasegawa, Akiko Kitamura, Naoki Ishiguro, Kinji Ohno
- Organizer
  Orthopaedic Research Society (ORS) Annual meeting
- Place of Presentation
  Orlando,U.S.A.
- Year and Date
  2016-03-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10439
[Presentation] Clinical feasibility of oral administration of meclozine for the treatment of short stature in achondroplasia2016
- Author(s)
  Masaki Matsushita, Hiroshi Kitoh, Kenichi Mishima, Naoki Ishiguro, Kinji Ohno
- Organizer
  Annual meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Atlanta （ＵＳＡ）
- Year and Date
  2016-09-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] 軟骨無形成症の低身長に対する治療2016
- Author(s)
  鬼頭浩史、三島健一、松下雅樹
- Organizer
  第34回日本骨代謝学会・第3回アジア太平洋骨代謝学会
- Place of Presentation
  大阪国際会議場（大阪市北区）
- Year and Date
  2016-07-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] Transplantation of culture-expanded bone marrow cells and platelet rich plasma in limb lengthening Clinical trial and further improvement2016
- Author(s)
  Hiroshi Kitoh, Kenichi Mishima, Masaki Matsushita, Naoki Ishiguro
- Organizer
  60th Korean Orthopaedic Association
- Place of Presentation
  Incheon （Korea）
- Year and Date
  2016-10-19
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] Early radiographic parameters predictive of surgery-required relapse in idiopathic clubfoot treated using the Ponseti method2016
- Author(s)
  Kenichi Mishima, Hiroshi Kitoh, Masaki Matsushita, Hiroshi Sugiura, Sachi Hasegawa, Yoshihiro Nishida, Naoki Ishiguro
- Organizer
  37th SICOT Orthopaedic World Congress
- Place of Presentation
  Rome （Italy）
- Year and Date
  2016-09-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] 小児同種造血幹細胞移植後の下肢痛症例の検討2016
- Author(s)
  三島　健一、鬼頭　浩史、松下　雅樹、門野　泉、杉浦　洋、北村　暁子、西田　佳弘、石黒　直樹
- Organizer
  第27回日本小児整形外科学会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-16K10854
[Presentation] Meclozineによる軟骨無形成症の根本的治療の可能性と限界2016
- Author(s)
  松下雅樹、鬼頭浩史、三島健一、杉浦洋、西田佳弘、石黒直樹、大野欽司
- Organizer
  第34回日本骨代謝学会・第3回アジア太平洋骨代謝学会
- Place of Presentation
  大阪国際会議場（大阪市北区）
- Year and Date
  2016-07-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] Meclozine has a potential effects on short stature and foramen magnum stenosis in transgenic mice with achondroplasia2015
- Author(s)
  Masaki Matsushita, Hiroshi Kitoh, Kenichi Mishima, Hiroshi Sugiura, Sachi Hasegawa, Akiko Kitamura, Naoki Ishiguro, Kinji Ohno
- Organizer
  7th International Conference on Children’s Bone Health (ICCBH)
- Place of Presentation
  Salzburg,Austria
- Year and Date
  2015-06-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10439
[Presentation] 軟骨無形成症における根本的治療薬の開発2015
- Author(s)
  松下雅樹、鬼頭浩史、三島健一、杉浦　洋、長谷川　幸、北村　暁子、西田佳弘、石黒直樹、大野欽司
- Organizer
  第27回日本整形外科学会骨系統疾患研究会
- Place of Presentation
  長良川国際会議場（岐阜県岐阜市）
- Year and Date
  2015-12-05
- Data Source
  KAKENHI-PROJECT-15K10439
[Presentation] Transplantation of culture-expanded bone marrow cells and platelet rich plasma during distraction osteogenesis of the long bones2015
- Author(s)
  Hiroshi Kitoh, Kenichi Mishima, Masaki Matsushita, Naoki Ishiguro
- Organizer
  4th Tissue Engineering and Regenerative Medicine International Society
- Place of Presentation
  Boston,U.S.A.
- Year and Date
  2015-09-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] Promoting osteoblastogenesis using Lansoprazole2015
- Author(s)
  Kenichi Mishima, Bisei Ohkawara, Hiroshi Kitoh, Yuta Tsukagoshi Okabe, Hiroshi Sugiura, Masaki Matsushita, Naoki Ishiguro, Kinji Ohno
- Organizer
  4th Tissue Engineering and Regenerative Medicine International Society
- Place of Presentation
  Boston,U.S.A.
- Year and Date
  2015-09-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] meclozineは軟骨無形成症における大後頭孔および脊柱管狭窄を改善しうる2015
- Author(s)
  松下雅樹、鬼頭浩史、三島健一、杉浦　洋、長谷川　幸、北村　暁子、西田佳弘、石黒直樹、大野欽司
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場ＡＮＡクラウンプラザホテル富山富山市民プラザ（富山県富山市）
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-15K10439
[Presentation] 軟骨無形成症治療の現在と未来2015
- Author(s)
  松下雅樹
- Organizer
  Achondroplasia Workshop
- Place of Presentation
  後楽ホテル（岡山県岡山市）
- Year and Date
  2015-11-21
- Invited
- Data Source
  KAKENHI-PROJECT-15K10439
[Presentation] Transplantation of culture-expanded bone marrow cells and platelet rich plasma in lower limb lengthening for short stature patients2015
- Author(s)
  Hiroshi Kitoh, Kenichi Mishima, Masaki Matsushita, Naoki Ishiguro
- Organizer
  The 7th International Conference on Children’s Bone Health
- Place of Presentation
  Salzburg,Austria
- Year and Date
  2015-06-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548
[Presentation] Meclozine has a potential effect on short stature and foramen magnum stenosis in transgenic mice with achondroplasia2015
- Author(s)
  Masaki Matsushita, Hiroshi Kitoh, Kenichi Mishima, Hiroshi Sugiura, Sachi Hasegawa, Akiko Kitamura, Naoki Ishiguro, Ohno Kinj.
- Organizer
  The 7th International Conference on Children’s Bone Health
- Place of Presentation
  Salzburg,Austria
- Year and Date
  2015-06-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15548

1. Kitoh Hiroshi (40291174)

# of Collaborated Projects: 11 results

# of Collaborated Products: 177 results
2. MISHIMA KENICHI (40646519)

# of Collaborated Projects: 11 results

# of Collaborated Products: 164 results
3. 神谷庸成 (50845542)

# of Collaborated Projects: 6 results

# of Collaborated Products: 77 results
4. 長田侃 (80815324)

# of Collaborated Projects: 5 results

# of Collaborated Products: 15 results
5. 杉浦洋 (40750477)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
6. 松下祐樹 (00713827)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
7. 細野祥之 (60820363)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 森田淳平 (50737046)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 尾崎遼 (10743346)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 住田吉慶 (50456654)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 今釜史郎 (40467288)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 石塚真哉 (40813316)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 竹上靖彦 (50755345)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 中島宏彰 (70710101)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. OGI Tomoo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. TSUCHIYA Shuhei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 大野欽司

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. 石黒直樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
19. 藤原清香

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 増田章男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 大河原美静

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Matsushita Masaki 松下 雅樹

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新規FGFR3インヒビターの骨軟骨代謝における効果と作用機序の検討Principal Investigator

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FGFR3インヒビターのマウスモデルへの長期投与と作用機序の検討Principal Investigator

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新規軟骨無形成症治療薬開発研究Principal Investigator

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Animal study for evaluating the effect of meclozine on FGFR3 signalingPrincipal Investigator

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Matsushita Masaki 松下雅樹