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TSUNETOU Motokazu  經遠 智一

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TSUNETO Motokazu  經遠 智一

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Researcher Number 60730207
Other IDs
Affiliation (Current) 2025: 鳥取大学, 医学部, 助教
Affiliation (based on the past Project Information) *help 2020 – 2025: 鳥取大学, 医学部, 助教
2019 – 2020: 鳥取大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field
Principal Investigator
Basic Section 49020:Human pathology-related / Basic Section 53020:Cardiology-related
Except Principal Investigator
Basic Section 48020:Physiology-related / Basic Section 42040:Laboratory animal science-related / Basic Section 90110:Biomedical engineering-related / Basic Section 53020:Cardiology-related
Keywords
Principal Investigator
血管内皮細胞 / 尿酸塩結晶 / 高尿酸血症 / インフラマソーム / ヒト / マウス / 線維芽細胞 / 心臓常在マクロファージ / 心房細動 / 常在マクロファージ / 心臓 … More
Except Principal Investigator
… More ヒトiPS細胞 / ペースメーカ細胞 / pacemaker cells / human iPS cells / cardiomyocytes / Patch-seq / 洞結節ペースメーカ細胞 / グルコース輸送 / アポトーシス / 体外培養 / ラット / 着床前胚 / ヒト多能性幹細胞 / 分化誘導 / イオンチャネル / 心筋 / オルガノイド / 心臓前駆細胞 / 心外膜 / 蛍光タンパク質 / 心筋細胞 / feature value / sinus nodal cell / iPS cell / machine learning / 自動能 / 特徴量 / 形態 / 機械学習 / 洞結節細胞 / 深層学習 / iPS細胞 / SAN cell / automaticity / deep learning / sinoatrial node / iPS Less
  • Research Projects

    (7 results)
  • Research Products

    (24 results)
  • Co-Researchers

    (6 People)
  •  高尿酸血症における血管障害の新たなメカニズムの解明Principal Investigator

    • Principal Investigator
      經遠 智一
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Tottori University
  •  The relevance of glucose transport and apoptosis in rat preimplantation embryos cultured in vitro

    • Principal Investigator
      中村 和臣
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 42040:Laboratory animal science-related
    • Research Institution
      Tottori University
  •  Patch-seqを用いた包括的解析によるiPS細胞由来心筋の解析

    • Principal Investigator
      白吉 安昭
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48020:Physiology-related
    • Research Institution
      Tottori University
  •  高尿酸血症における尿酸塩結晶の関節以外への影響の検討Principal Investigator

    • Principal Investigator
      經遠 智一
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Tottori University
  •  Deep learning-based identification of sinoatrial node-like pacemaker cells from SHOX2/HCN4 double positive cells differentiated from human iPS cells

    • Principal Investigator
      HISATOME Ichiro
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Tottori University
  •  Development of basic technology for the production of cardiac organoids derived from human pluripotent stem cells

    • Principal Investigator
      SHIRAYOSHI Yasuaki
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      Tottori University
  •  A study of the novel molecular mechanism of atrial fibrillation induced by cardiac resident macrophages in hyperuricemiaPrincipal Investigator

    • Principal Investigator
      TSUNETO Motokazu
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Tottori University

All 2023 2022 2021 2020 2019

All Journal Article Presentation

  • [Journal Article] Effects of Conditioned Medium of Adipose-Derived Stem Cells Exposed to Platelet-Rich Plasma on the Expression of Endothelial Nitric Oxide Synthase and Angiogenesis by Endothelial Cells2023

    • Author(s)
      Morita Maki、Suyama Yoshiko、Notsu Tomomi、Fukuoka Kohei、Ikuta Kento、Kanayama Haruka、Umeda Ryunosuke、Teraoka Shogo、Minato Hiroyuki、Ninomiya Haruaki、Tsuneto Motokazu、Shirayoshi Yasuaki、Hisatome Ichiro、Yagi Shunjiro
    • Journal Title

      Annals of Plastic Surgery

      Volume: 90 Issue: 2 Pages: 171-179

    • DOI

      10.1097/sap.0000000000003368

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08557, KAKENHI-PROJECT-20K09865, KAKENHI-PROJECT-22K06979
  • [Journal Article] Deep learning-based identification of sinoatrial node-like pacemaker cells from SHOX2/HCN4 double-positive cells differentiated from human iPS cells2023

    • Author(s)
      Wakimizu T, Naito J, Ishida M, Kurata Y, Tsuneto M, Shirayoshi Y, Hisatome I.
    • Journal Title

      J. Arrhythm

      Volume: 39 Issue: 4 Pages: 664-668

    • DOI

      10.1002/joa3.12883

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K06335, KAKENHI-PROJECT-20K12623
  • [Journal Article] SHOX2 refines the identification of human sinoatrial nodal cell population in the in vitro cardiac differentiation.2022

    • Author(s)
      Wakimizu T, Morikawa K, Fukumura K, Yuki T, Adachi T, Kurata Y, Miake J, Hisatome I, Tsuneto M, Shirayoshi Y.
    • Journal Title

      Regen Ther.

      Volume: 21 Pages: 239-249

    • DOI

      10.1016/j.reth.2022.07.012

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K12623, KAKENHI-PROJECT-20K20662, KAKENHI-PROJECT-19K08557, KAKENHI-PROJECT-20K08423, KAKENHI-PROJECT-22K06979
  • [Journal Article] α1-Adrenergic receptor mediates adipose-derived stem cell sheet-induced protection against chronic heart failure after myocardial infarction in rats2022

    • Author(s)
      Horie H, Hisatome I, Kurata Y, Yamamoto Y, Notsu T, Adachi M, Li P, et al
    • Journal Title

      Hypertension research

      Volume: 45 Issue: 2 Pages: 283-291

    • DOI

      10.1038/s41440-021-00802-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08074, KAKENHI-PROJECT-19K08557, KAKENHI-PROJECT-21K08844
  • [Journal Article] Kv1.5 channel mediates monosodium urate-induced activation of NLRP3 inflammasome in macrophages and arrhythmogenic effects of urate on cardiomyocytes2022

    • Author(s)
      Peili Li, Yasutaka Kurata, Fikri Taufiq, et al
    • Journal Title

      Molecular Biology Reports

      Volume: online ahead of print Issue: 7 Pages: 0-0

    • DOI

      10.1007/s11033-022-07378-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08074, KAKENHI-PROJECT-20K17168, KAKENHI-PROJECT-19K08557, KAKENHI-PROJECT-22K06979
  • [Journal Article] Esm1 and Stc1 as Angiogenic Factors Responsible for Protective Actions of Adipose-Derived Stem Cell Sheets on Chronic Heart Failure After Rat Myocardial Infarction2021

    • Author(s)
      Watanabe Mai、Horie Hiromu、Kurata Yasutaka、Inoue Yumiko、Notsu Tomomi、Wakimizu Takayuki、Adachi Maya、Yamamoto Kenshiro、Morikawa Kumi、Kuwabara Masanari、Sakaguchi Takuki、Morisaki Takayuki、Miake Junichiro、Nishimura Motonobu、Tsuneto Motokazu、Shirayoshi Yasuaki、Ito Shin、Kitakaze Masafumi、et al.
    • Journal Title

      Circ J

      Volume: 85 Issue: 5 Pages: 657-666

    • DOI

      10.1253/circj.CJ-20-0877

    • NAID

      130008028975

    • ISSN
      1346-9843, 1347-4820
    • Year and Date
      2021-04-23
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08557, KAKENHI-PROJECT-18K08757, KAKENHI-PROJECT-21K08844, KAKENHI-PROJECT-20K20662
  • [Journal Article] Pretreatment with cilnidipine attenuates hypoxia/reoxygenation injury in HL-1 cardiomyocytes through enhanced NO production and action potential shortening2020

    • Author(s)
      Minato Hiroyuki、Hisatome Ichiro、Kurata Yasutaka、Notsu Tomomi、Nakasone Naoe、Ninomiya Haruaki、Hamada Toshihiro、Tomomori Takuya、Okamura Akihiro、Miake Junichiro、Tsuneto Motokazu、Shirayoshi Yasuaki、Endo Ryo、Otsuki Akihiro、Okada Futoshi、Inagaki Yoshimi
    • Journal Title

      Hypertension Research

      Volume: 43 Issue: 5 Pages: 380-388

    • DOI

      10.1038/s41440-019-0391-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08557, KAKENHI-PROJECT-17K08761, KAKENHI-PROJECT-20K20662
  • [Journal Article] Evidence for Urate Uptake Through Monocarboxylate Transporter 9 Expressed in Mammalian Cells and Its Enhancement by Heat Shock2020

    • Author(s)
      Otani Naoyuki、Kurata Yasutaka、Maharani Nani、Kuwabara Masanari、Ikeda Nobuhito、Notsu Tomomi、Li Peili、Miake Junichiro、Yoshida Akio、Sakaguchi Hiromi、Higaki Katsumi、Nakasone Naoe、Tsuneto Motokazu、Shirayoshi Yasuaki、Ouchi Motoshi、Ninomiya Haruaki、Yamamoto Kazuhiro、Anzai Naohiko、Hisatome Ichiro
    • Journal Title

      Circulation Reports

      Volume: 2 Issue: 8 Pages: 425-432

    • DOI

      10.1253/circrep.cr-20-0016

    • NAID

      130007885744

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08557, KAKENHI-PROJECT-20K20662, KAKENHI-PROJECT-18K08200, KAKENHI-PROJECT-18K08074
  • [Journal Article] β-Adrenergic Blocker, Carvedilol, Abolishes Ameliorating Actions of Adipose-Derived Stem Cell Sheets on Cardiac Dysfunction and Remodeling After Myocardial Infarction2019

    • Author(s)
      Adachi Maya、Watanabe Mai、Kurata Yasutaka、Inoue Yumiko、Notsu Tomomi、Yamamoto Kenshiro、Horie Hiromu、Tanno Shogo、Morita Maki、Miake Junichiro、Hamada Toshihiro、Kuwabara Masanari、Nakasone Naoe、Ninomiya Haruaki、Tsuneto Motokazu、et al.
    • Journal Title

      Circ J

      Volume: 83 Issue: 11 Pages: 2282-2291

    • DOI

      10.1253/circj.CJ-19-0261

    • NAID

      130007733310

    • ISSN
      1346-9843, 1347-4820
    • Year and Date
      2019-10-25
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08557
  • [Presentation] Developmental fate and cellular characteristics exhibited by HCN4-positive cardiomyocytes derived from human iPS cells.2023

    • Author(s)
      Kumi Morikawa, Takashi Adachi, Akari Imagawa, Masato Shigenaga, Takayuki Wakimizu, Ichiro Hisatome, Motokazu Tsuneto, Yasuaki Shirayoshi
    • Organizer
      CARDIOVASCULAR BIOENGINEERING (CVBE) SYMPOSIUM 2023, Kyoto, Japan
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K06335
  • [Presentation] 尿酸塩結晶がヒト血管内皮細胞へ与える影響の解析2023

    • Author(s)
      經遠 智一, 勝倉 由夏, 久留 一郎
    • Organizer
      第56回日本痛風・尿酸核酸学会総会
    • Data Source
      KAKENHI-PROJECT-19K08557
  • [Presentation] Developmental fate and cellular characteristics exhibited by HCN4-positive cardiomyocytes derived from human iPS cells.2023

    • Author(s)
      Morikawa K, Adachi T, Imagawa A, Shigenaga M, Wakimizu T, Hisatome I, Tsuneto M, Shirayoshi Y.
    • Organizer
      Cardiovascular Bioengineering (CVBE) Symposium 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K12623
  • [Presentation] 尿酸塩結晶がヒト血管内皮細胞へ与える影響の解析2023

    • Author(s)
      經遠 智一, 勝倉 由夏, 久留 一郎
    • Organizer
      第56回日本痛風・尿酸核酸学会総会
    • Data Source
      KAKENHI-PROJECT-22K06979
  • [Presentation] Direct effects of monosodium urate crystal on human endothelial cells in hyperuricemia2022

    • Author(s)
      Mototkazu Tsuneto, Yuka Katsukura, Naruomi Yamada, Akika Fukawa, Ichiro Hisatome
    • Organizer
      第51回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-19K08557
  • [Presentation] ヒト血管内皮細胞への尿酸塩結晶の影響の検討2022

    • Author(s)
      經遠 智一, 江橋 由夏, 久留 一郎
    • Organizer
      第55回日本痛風・尿酸核酸学会総会
    • Data Source
      KAKENHI-PROJECT-19K08557
  • [Presentation] ヒトiPS細胞を用いた心臓前駆細胞の選択的分取法の開発と特性解析2022

    • Author(s)
      重永雅人, 今川明梨, 谷本久実, 經遠智一, 白吉安昭
    • Organizer
      第45回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K12623
  • [Presentation] Direct effects of monosodium urate crystal on human endothelial cells in hyperuricemia2022

    • Author(s)
      經遠 智一, 勝倉 由夏, 久留 一郎
    • Organizer
      第51回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-22K06979
  • [Presentation] HCN4/Shox2遺伝子標識によるヒトiPS細胞からの心臓洞結節ペースメーカ細胞の分取システムの構築2021

    • Author(s)
      脇水孝之、經遠智一、白吉安昭、久留一郎
    • Organizer
      心電学関連春期大会2021
    • Data Source
      KAKENHI-PROJECT-20K12623
  • [Presentation] ヒトiPS細胞に由来するHCN4陽性心筋細胞のはっせい・分化能とその特性解析2021

    • Author(s)
      谷本久実、足立隆、經遠智一、久留一郎、白吉安昭
    • Organizer
      第44回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K12623
  • [Presentation] HCN4/Shox2 遺伝子標識によるヒト iPS 細胞からの心臓洞房結節ペースメーカ細胞の分取システムの構築2021

    • Author(s)
      脇水 孝之, 經遠 智一, 白吉 安昭, 久留 一郎
    • Organizer
      心電学関連春季大会2021
    • Data Source
      KAKENHI-PROJECT-19K08557
  • [Presentation] An investigation of human cardiac pacemaker cells differentiation process using human induced pluripotent stem cells visualizing HCN4/Shox2 gene2021

    • Author(s)
      Wakimizu T, Tsuneto M, Shirayoshi Y, Hisatome I
    • Organizer
      The18th Stem Cell Research Symposium
    • Data Source
      KAKENHI-PROJECT-19K08557
  • [Presentation] 予定心臓領域特異的マーカー遺伝子の発現を可視化したIPS細胞株の樹立2021

    • Author(s)
      重永雅人、今川明梨、經遠智一、久留一郎、白吉安昭
    • Organizer
      第44回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K12623
  • [Presentation] 心房細動関連遺伝子PRRX1のヒト心房筋様細胞における機能解析2021

    • Author(s)
      幸哲夫、經遠智一、三明淳一郎、久留一郎、白吉安昭
    • Organizer
      第44回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K12623
  • [Presentation] HCN4/Shox2遺伝子標識によるヒトiPS細胞由来心臓ペースメーカ細胞の分取システムの構築と機能解析2021

    • Author(s)
      脇水 孝之, 經遠 智一, 久留一郎, 白吉 安昭
    • Organizer
      第 44回日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-19K08557
  • 1.  SHIRAYOSHI Yasuaki (90249946)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 9 results
  • 2.  HISATOME Ichiro (60211504)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 3.  森川 久未 (90707217)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 4.  李 佩俐 (40464292)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 5.  三明 淳一朗 (40372677)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  中村 和臣 (90598137)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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