Oue Kana 大植香菜

Researcher Number	60760329
Other IDs
Affiliation (Current)	2025: 広島大学, 病院(歯), 助教
Affiliation (based on the past Project Information) *help	2025: 広島大学, 病院(歯), 助教 2019 – 2023: 広島大学, 病院(歯), 助教 2016 – 2018: 広島大学, 病院(歯), 歯科診療医 2015: 広島大学, 大学病院, 歯科診療医
Review Section/Research Field	Principal Investigator Surgical dentistry / Basic Section 57030:Conservative dentistry-related / Basic Section 57060:Surgical dentistry-related Except Principal Investigator Basic Section 59040:Nutrition science and health science-related
Keywords	Principal Investigator 肥満 / 神経炎症 / 認知症 / 認知機能障害 / ミクログリア / 歯周病 / UCP1 / エネルギー代謝 / 褐色脂肪細胞 / 認知機能低下 / 慢性炎症 / 認知機能 / ＵＣＰ１ … More Except Principal Investigator … More ストレス脆弱性 / 神経炎症 / 精神ストレス / 肥満病態 / グリア Less

Mechanisms of Stress Vulnerability via Microglial Dysfunction in Obesity
- Principal Investigator
  
  山脇洋輔
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Daiichi University, College of Pharmaceutical Sciences
Elucidating the mechanisms of interaction between obesity pathology and periodontal infection on cognitive functionPrincipal Investigator
- Principal Investigator
  
  大植香菜
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Hiroshima University
肥満が助長する歯周病感染による認知機能障害における相互作用メカニズムの解明研究Principal Investigator
- Principal Investigator
  
  大植香菜
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Hiroshima University
Studies on molecular mechanisms of brown adipocyte for controlling obesity.Principal Investigator
- Principal Investigator
  
  OUE KANA
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hiroshima University
Research on brown adipocyte for controlling of obesityPrincipal Investigator
- Principal Investigator
  
  Oue Kana
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Surgical dentistry
- Research Institution
  Hiroshima University

All 2023 2021 2019 2018 2017 2015

All Journal Article Presentation

[Journal Article] Phospholipase C-related catalytically inactive protein regulates lipopolysaccharide-induced hypothalamic inflammation-mediated anorexia in mice2019
- Author(s)
  Yamawaki Yosuke、Shirawachi Satomi、Mizokami Akiko、Nozaki Kanako、Ito Hikaru、Asano Satoshi、Oue Kana、Aizawa Hidenori、Yamawaki Shigeto、Hirata Masato、Kanematsu Takashi
- Journal Title
  
  Neurochemistry International
  
  Volume: 131 Pages: 104563-104563
- DOI
  10.1016/j.neuint.2019.104563
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06504, KAKENHI-PROJECT-18K09521, KAKENHI-PROJECT-17K19766, KAKENHI-PROJECT-19K17112, KAKENHI-PROJECT-17H01595, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-17K19459, KAKENHI-PROJECT-17K17254
[Journal Article] Phospholipase C-related catalytically inactive protein: A novel signaling molecule for modulating fat metabolism and energy expenditure2019
- Author(s)
  Kanematsu T, Oue K, Okumura T, Harada K, Yamawaki Y, Asano S, Mizokami A, Irifune M, Hirata M
- Journal Title
  
  J Oral Biosci
  
  Volume: 61(2) Issue: 2 Pages: 65-72
- DOI
  10.1016/j.job.2019.04.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09812, KAKENHI-PROJECT-17K19766, KAKENHI-PROJECT-17H01595, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-17K17254
[Journal Article] Chronic cold exposure enhances the induction of uncoupling protein 1 in adipose tissues of phospholipase C-related catalytically inactive protein-knockout mice2017
- Author(s)
  Kana Oue, Yosuke Yamawaki, Satoshi Asano, Mizokami Akiko, Masato Hirata, Masahiro Irifune, Takashi Kanematsu
- Journal Title
  
  Ｊｏｕｒｎａｌ　ｏｆ　Ｏｒａｌ　Ｂｉｏｓｃｉｅｎｃｅｓ
  
  Volume: 59 Pages: 108-112
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K17254
[Journal Article] Phospholipase C-related catalytically inactive protein-knockout mice display increased induction of uncoupling protein 1 in adipose tissues following chronic cold exposure.2017
- Author(s)
  Kana Oue, Yosuke Yamawaki, Satoshi Asano, Mizokami Akiko, Masato Hirata, Masahiro Irifune, Takashi Kanematsu.
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 印刷中 Issue: 2 Pages: 108-112
- DOI
  10.1016/j.job.2017.04.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H06433, KAKENHI-PROJECT-15K19731, KAKENHI-PROJECT-15K20372, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-15K11313, KAKENHI-PROJECT-16K20421
[Journal Article] General anesthetic actions on GABAA receptors in vivo are reduced in phospholipase C-related catalytically inactive protein knockout mice.2017
- Author(s)
  Hayashiuchi M, Kitayama T, Morita K, Yamawaki Y, Oue K, Yoshinaka T, Asano S, Harada K, Kang Y, Hirata M, Irifune M, Okada M, Kanematsu T.
- Journal Title
  
  Journal of Anesthesia
  
  Volume: in press Issue: 4 Pages: 531-538
- DOI
  10.1007/s00540-017-2350-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19731, KAKENHI-PROJECT-15K20372, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K17254, KAKENHI-PROJECT-15K11039, KAKENHI-PROJECT-15K11313
[Journal Article] Phospholipase C-related catalytically inactive protein can regulate obesity, a state of peripheral inflammation.2017
- Author(s)
  Yamawaki Y, Oue K, Shirawachi S, Asano S, Harada K, Kanematsu T.
- Journal Title
  
  Japanese Dental Science Review
  
  Volume: 53（1） Issue: 1 Pages: 18-24
- DOI
  10.1016/j.jdsr.2016.06.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H06433, KAKENHI-PROJECT-15K19731, KAKENHI-PROJECT-15K11039, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K17254
[Journal Article] New molecular basis in the regulation of lipolysis via dephosphorylation2015
- Author(s)
  大植香菜，原田佳枝，兼松隆
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 146 Issue: 2 Pages: 93-97
- DOI
  10.1254/fpj.146.93
- NAID
  130005092136
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K11039, KAKENHI-PROJECT-15H06433, KAKENHI-PROJECT-26670809
[Journal Article] Phospholipase C-related catalytically inactive protein is a new modulator of thermogenesis promoted by β-adrenergic receptors in brown adipocytes2015
- Author(s)
  Kana Oue, Jun Zhang, Kae Harada-Hada, Satoshi Asano, Yosuke Yamawaki, Masaki Hayashiuchi, Hisako Furusho, Takashi Takata, Masahiro Irifune, Masato Hirata, Takashi Kanematsu
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 291 Issue: 8 Pages: 4185-96
- DOI
  10.1074/jbc.m115.705723
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11039, KAKENHI-PROJECT-15K19731, KAKENHI-PROJECT-15H06433, KAKENHI-PROJECT-26670809, KAKENHI-PROJECT-24229009, KAKENHI-PROJECT-15K20372, KAKENHI-PROJECT-15K11313, KAKENHI-PROJECT-16K20437
[Presentation] Periodontal infection in diet-induced obesity causes cognitive impairment associated with microglial activation.2023
- Author(s)
  Kana Oue, Yusuke Morioka, Eiji Imado, Testuya Tamura, Yosuke Yamawaki, Kazuhisa Ouhara, Mitsuhiro Yoshida, Takashi Kanematsu, Yukio Ago
- Organizer
  IAGG Asia/Oceania Regional Congress 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K18669
[Presentation] Periodontal infection in diet-induced obesity causes cognitive impairment associated with microglial activation.2023
- Author(s)
  Kana Oue, Yusuke Morioka, Eiji Imado, Testuya Tamura, Yosuke Yamawaki, Kazuhisa Ouhara, Mitsuhiro Yoshida, Takashi Kanematsu, Yukio Ago
- Organizer
  IAGG Asia/Oceania Regional Congress 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K09183
[Presentation] Periodontal infection in diet-induced obesity causes cognitive impairment associated with microglial activation2023
- Author(s)
  Kana Oue, Yusuke Morioka, Eiji Imado, Testuya Tamura, Yosuke Yamawaki, Kazuhisa Ouhara, Mitsuhiro Yoshida, Takashi Kanematsu, Yukio Ago
- Organizer
  the IAGG Asia/Oceania Regional Congress 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K18669
[Presentation] 肥満病態下における歯周病感染が引き起こす認知機能障害の機序の検討2021
- Author(s)
  大植　香菜、山脇　洋輔、兼松　隆
- Organizer
  第63回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-20K18669
[Presentation] 肥満制御研究の新潮流白色・褐色脂肪細胞の機能を制御しエネルギー代謝を調節する新しい分子基盤2018
- Author(s)
  兼松　隆，大植香菜, 山脇洋輔, 浅野智志
- Organizer
  第60回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-17K17254
[Presentation] 寒冷刺激で見られるPRIP遺伝子欠損マウスのUCP1発現の亢進2017
- Author(s)
  大植　香菜、入舩　正浩、兼松　隆
- Organizer
  第131回日本薬理学会近畿部会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2017-06-30
- Data Source
  KAKENHI-PROJECT-15H06433
[Presentation] The mechanism of phospholipase C-related catalytically inactive protein (PRIP)-mediated energy metabolism by β-adrenergic stimulation in brown adipocytes2017
- Author(s)
  Kana Oue, Yosuke Yamawaki, Satoshi Asano, Masahiro Irifune, Takashi Kanematsu
- Organizer
  第59回歯科基礎医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K17254
[Presentation] 寒冷刺激で見られるPRIP遺伝子欠損マウスのUCP1発現の亢進2017
- Author(s)
  大植香菜, 入舩正浩, 兼松　隆
- Organizer
  第131回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-17K17254

1. 森岡徳光 (20346505)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 吾郷由希夫 (50403027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 應原一久 (80550425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 山脇洋輔 (90584061)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. IRIFUNE Masahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 兼松隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. 原田佳枝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 伊藤日加瑠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Oue Kana 大植 香菜

Research Projects

Research Products

Co-Researchers

Mechanisms of Stress Vulnerability via Microglial Dysfunction in Obesity

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidating the mechanisms of interaction between obesity pathology and periodontal infection on cognitive functionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肥満が助長する歯周病感染による認知機能障害における相互作用メカニズムの解明研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Studies on molecular mechanisms of brown adipocyte for controlling obesity.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research on brown adipocyte for controlling of obesityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Phospholipase C-related catalytically inactive protein regulates lipopolysaccharide-induced hypothalamic inflammation-mediated anorexia in mice2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phospholipase C-related catalytically inactive protein: A novel signaling molecule for modulating fat metabolism and energy expenditure2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chronic cold exposure enhances the induction of uncoupling protein 1 in adipose tissues of phospholipase C-related catalytically inactive protein-knockout mice2017

Author(s)

Journal Title

Data Source

[Journal Article] Phospholipase C-related catalytically inactive protein-knockout mice display increased induction of uncoupling protein 1 in adipose tissues following chronic cold exposure.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] General anesthetic actions on GABAA receptors in vivo are reduced in phospholipase C-related catalytically inactive protein knockout mice.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phospholipase C-related catalytically inactive protein can regulate obesity, a state of peripheral inflammation.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] New molecular basis in the regulation of lipolysis via dephosphorylation2015

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Phospholipase C-related catalytically inactive protein is a new modulator of thermogenesis promoted by β-adrenergic receptors in brown adipocytes2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] Periodontal infection in diet-induced obesity causes cognitive impairment associated with microglial activation.2023

Author(s)

Organizer

Data Source

Oue Kana 大植香菜

[Presentation] 肥満制御研究の新潮流白色・褐色脂肪細胞の機能を制御しエネルギー代謝を調節する新しい分子基盤2018