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Oue Kana  大植 香菜

ORCIDConnect your ORCID iD *help
Researcher Number 60760329
Other IDs
Affiliation (Current) 2025: 広島大学, 病院(歯), 助教
Affiliation (based on the past Project Information) *help 2019 – 2023: 広島大学, 病院(歯), 助教
2016 – 2018: 広島大学, 病院(歯), 歯科診療医
2015: 広島大学, 大学病院, 歯科診療医
Review Section/Research Field
Principal Investigator
Surgical dentistry / Basic Section 57030:Conservative dentistry-related / Basic Section 57060:Surgical dentistry-related
Keywords
Principal Investigator
肥満 / 神経炎症 / 認知症 / 認知機能障害 / ミクログリア / 歯周病 / UCP1 / エネルギー代謝 / 褐色脂肪細胞 / 認知機能低下 / 慢性炎症 / 認知機能 / UCP1
  • Research Projects

    (4 results)
  • Research Products

    (16 results)
  • Co-Researchers

    (8 People)
  •  Elucidating the mechanisms of interaction between obesity pathology and periodontal infection on cognitive functionPrincipal Investigator

    • Principal Investigator
      大植 香菜
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57030:Conservative dentistry-related
    • Research Institution
      Hiroshima University
  •  肥満が助長する歯周病感染による認知機能障害における相互作用メカニズムの解明研究Principal Investigator

    • Principal Investigator
      大植 香菜
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Hiroshima University
  •  Studies on molecular mechanisms of brown adipocyte for controlling obesity.Principal Investigator

    • Principal Investigator
      OUE KANA
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Hiroshima University
  •  Research on brown adipocyte for controlling of obesityPrincipal Investigator

    • Principal Investigator
      Oue Kana
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Surgical dentistry
    • Research Institution
      Hiroshima University

All 2023 2021 2019 2018 2017 2015

All Journal Article Presentation

  • [Journal Article] Phospholipase C-related catalytically inactive protein regulates lipopolysaccharide-induced hypothalamic inflammation-mediated anorexia in mice2019

    • Author(s)
      Yamawaki Yosuke、Shirawachi Satomi、Mizokami Akiko、Nozaki Kanako、Ito Hikaru、Asano Satoshi、Oue Kana、Aizawa Hidenori、Yamawaki Shigeto、Hirata Masato、Kanematsu Takashi
    • Journal Title

      Neurochemistry International

      Volume: 131 Pages: 104563-104563

    • DOI

      10.1016/j.neuint.2019.104563

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06504, KAKENHI-PROJECT-18K09521, KAKENHI-PROJECT-17K19766, KAKENHI-PROJECT-19K17112, KAKENHI-PROJECT-17H01595, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-17K19459, KAKENHI-PROJECT-17K17254
  • [Journal Article] Phospholipase C-related catalytically inactive protein: A novel signaling molecule for modulating fat metabolism and energy expenditure2019

    • Author(s)
      Kanematsu T, Oue K, Okumura T, Harada K, Yamawaki Y, Asano S, Mizokami A, Irifune M, Hirata M
    • Journal Title

      J Oral Biosci

      Volume: 61(2) Issue: 2 Pages: 65-72

    • DOI

      10.1016/j.job.2019.04.002

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09812, KAKENHI-PROJECT-17K19766, KAKENHI-PROJECT-17H01595, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-17K17254
  • [Journal Article] Chronic cold exposure enhances the induction of uncoupling protein 1 in adipose tissues of phospholipase C-related catalytically inactive protein-knockout mice2017

    • Author(s)
      Kana Oue, Yosuke Yamawaki, Satoshi Asano, Mizokami Akiko, Masato Hirata, Masahiro Irifune, Takashi Kanematsu
    • Journal Title

      Journal of Oral Biosciences

      Volume: 59 Pages: 108-112

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K17254
  • [Journal Article] Phospholipase C-related catalytically inactive protein-knockout mice display increased induction of uncoupling protein 1 in adipose tissues following chronic cold exposure.2017

    • Author(s)
      Kana Oue, Yosuke Yamawaki, Satoshi Asano, Mizokami Akiko, Masato Hirata, Masahiro Irifune, Takashi Kanematsu.
    • Journal Title

      Journal of Oral Biosciences

      Volume: 印刷中 Issue: 2 Pages: 108-112

    • DOI

      10.1016/j.job.2017.04.001

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H06433, KAKENHI-PROJECT-15K19731, KAKENHI-PROJECT-15K20372, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-15K11313, KAKENHI-PROJECT-16K20421
  • [Journal Article] General anesthetic actions on GABAA receptors in vivo are reduced in phospholipase C-related catalytically inactive protein knockout mice.2017

    • Author(s)
      Hayashiuchi M, Kitayama T, Morita K, Yamawaki Y, Oue K, Yoshinaka T, Asano S, Harada K, Kang Y, Hirata M, Irifune M, Okada M, Kanematsu T.
    • Journal Title

      Journal of Anesthesia

      Volume: in press Issue: 4 Pages: 531-538

    • DOI

      10.1007/s00540-017-2350-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K19731, KAKENHI-PROJECT-15K20372, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K17254, KAKENHI-PROJECT-15K11039, KAKENHI-PROJECT-15K11313
  • [Journal Article] Phospholipase C-related catalytically inactive protein can regulate obesity, a state of peripheral inflammation.2017

    • Author(s)
      Yamawaki Y, Oue K, Shirawachi S, Asano S, Harada K, Kanematsu T.
    • Journal Title

      Japanese Dental Science Review

      Volume: 53(1) Issue: 1 Pages: 18-24

    • DOI

      10.1016/j.jdsr.2016.06.001

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H06433, KAKENHI-PROJECT-15K19731, KAKENHI-PROJECT-15K11039, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K17254
  • [Journal Article] New molecular basis in the regulation of lipolysis via dephosphorylation2015

    • Author(s)
      大植香菜, 原田佳枝, 兼松隆
    • Journal Title

      Folia Pharmacologica Japonica

      Volume: 146 Issue: 2 Pages: 93-97

    • DOI

      10.1254/fpj.146.93

    • NAID

      130005092136

    • ISSN
      0015-5691, 1347-8397
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K11039, KAKENHI-PROJECT-15H06433, KAKENHI-PROJECT-26670809
  • [Journal Article] Phospholipase C-related catalytically inactive protein is a new modulator of thermogenesis promoted by β-adrenergic receptors in brown adipocytes2015

    • Author(s)
      Kana Oue, Jun Zhang, Kae Harada-Hada, Satoshi Asano, Yosuke Yamawaki, Masaki Hayashiuchi, Hisako Furusho, Takashi Takata, Masahiro Irifune, Masato Hirata, Takashi Kanematsu
    • Journal Title

      Journal of Biological Chemistry

      Volume: 291 Issue: 8 Pages: 4185-96

    • DOI

      10.1074/jbc.m115.705723

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K11039, KAKENHI-PROJECT-15K19731, KAKENHI-PROJECT-15H06433, KAKENHI-PROJECT-26670809, KAKENHI-PROJECT-24229009, KAKENHI-PROJECT-15K20372, KAKENHI-PROJECT-15K11313, KAKENHI-PROJECT-16K20437
  • [Presentation] Periodontal infection in diet-induced obesity causes cognitive impairment associated with microglial activation.2023

    • Author(s)
      Kana Oue, Yusuke Morioka, Eiji Imado, Testuya Tamura, Yosuke Yamawaki, Kazuhisa Ouhara, Mitsuhiro Yoshida, Takashi Kanematsu, Yukio Ago
    • Organizer
      IAGG Asia/Oceania Regional Congress 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K18669
  • [Presentation] Periodontal infection in diet-induced obesity causes cognitive impairment associated with microglial activation.2023

    • Author(s)
      Kana Oue, Yusuke Morioka, Eiji Imado, Testuya Tamura, Yosuke Yamawaki, Kazuhisa Ouhara, Mitsuhiro Yoshida, Takashi Kanematsu, Yukio Ago
    • Organizer
      IAGG Asia/Oceania Regional Congress 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K09183
  • [Presentation] Periodontal infection in diet-induced obesity causes cognitive impairment associated with microglial activation2023

    • Author(s)
      Kana Oue, Yusuke Morioka, Eiji Imado, Testuya Tamura, Yosuke Yamawaki, Kazuhisa Ouhara, Mitsuhiro Yoshida, Takashi Kanematsu, Yukio Ago
    • Organizer
      the IAGG Asia/Oceania Regional Congress 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K18669
  • [Presentation] 肥満病態下における歯周病感染が引き起こす認知機能障害の機序の検討2021

    • Author(s)
      大植 香菜、山脇 洋輔、兼松 隆
    • Organizer
      第63回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-20K18669
  • [Presentation] 肥満制御研究の新潮流 白色・褐色脂肪細胞の機能を制御しエネルギー代謝を調節する新しい分子基盤2018

    • Author(s)
      兼松 隆,大植香菜, 山脇洋輔, 浅野智志
    • Organizer
      第60回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K17254
  • [Presentation] 寒冷刺激で見られるPRIP遺伝子欠損マウスのUCP1発現の亢進2017

    • Author(s)
      大植 香菜、入舩 正浩、兼松 隆
    • Organizer
      第131回日本薬理学会近畿部会
    • Place of Presentation
      愛知県名古屋市
    • Year and Date
      2017-06-30
    • Data Source
      KAKENHI-PROJECT-15H06433
  • [Presentation] The mechanism of phospholipase C-related catalytically inactive protein (PRIP)-mediated energy metabolism by β-adrenergic stimulation in brown adipocytes2017

    • Author(s)
      Kana Oue, Yosuke Yamawaki, Satoshi Asano, Masahiro Irifune, Takashi Kanematsu
    • Organizer
      第59回歯科基礎医学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K17254
  • [Presentation] 寒冷刺激で見られるPRIP遺伝子欠損マウスのUCP1発現の亢進2017

    • Author(s)
      大植香菜, 入舩正浩, 兼松 隆
    • Organizer
      第131回日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-17K17254
  • 1.  森岡 徳光 (20346505)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  吾郷 由希夫 (50403027)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  應原 一久 (80550425)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  IRIFUNE Masahiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  兼松 隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 6.  原田 佳枝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  伊藤 日加瑠
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  山脇 洋輔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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