Bai Hanako 唄花子

Researcher Number	60775443
Other IDs
Affiliation (Current)	2025: 北海道大学, 農学研究院, 助教
Affiliation (based on the past Project Information) *help	2017 – 2025: 北海道大学, 農学研究院, 助教
Review Section/Research Field	Principal Investigator Basic Section 42010:Animal production science-related / Animal production science Except Principal Investigator Basic Section 42010:Animal production science-related
Keywords	Principal Investigator ウシ / 子宮 / インターフェロン誘導性遺伝子 / 免疫細胞 / インターフェロン誘導性因子 / インターフェロン / 胚 / 遺伝子発現 / 反芻動物 / 低酸素 … More Except Principal Investigator … More ウシ / 初期胚 / 初期胚発生 / 細胞分化 / 栄養膜細胞 / 個体発生 / 胚盤胞期胚 / 胎盤構成細胞 / 二核細胞 / ウシ内在性レトロウイルス / SNX5 / 内在性レトロウイルス / ２核細胞 / 栄養膜幹細胞 / 胎盤形成 / 気液界面培養 / 動物生産 / Yap1 / Nf2 / Hippo経路 / ガラス化保存 / マウス / オルガノイド / PBMC / 着床成立 / 生体外モデル樹立 / 妊娠補助剤開発 / 子宮オルガノイド / 子宮内環境 / IL-10 / IL-6 / 末梢血単核球 / 子宮灌流液 / 生体外モデル / 着床 / 子宮 / 栄養外胚葉 / 内部細胞塊 / 育種 / ゲノミック評価 Less

インターフェロン誘導性遺伝子の着床期血管新生作用の解明Principal Investigator
- Principal Investigator
  
  唄花子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Hokkaido University
ウシ胚気液界面培養法の改良による胚盤葉上層形成機構の解明
- Principal Investigator
  
  川原学
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Hokkaido University
子宮環境構築のための新規インターフェロン誘導性遺伝子の機能解析Principal Investigator
- Principal Investigator
  
  唄花子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Hokkaido University
Analysis of differentiation mechanism of bovine trophoblast cells into placental component cells.
- Principal Investigator
  
  櫻井敏博
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Ohu University
Maintenance of trophectoderm in bovine vitrified embryos based on elucidation of regulatory mechanism of early embryonic differentiation
- Principal Investigator
  
  Kawahara Manabu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Hokkaido University
Identification and analysis of interferon stimulated genes in the uterusPrincipal Investigator
- Principal Investigator
  
  Bai Hanako
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Hokkaido University
Intrauterine environment during implantation in bovine pregnancy.
- Principal Investigator
  
  Sakurai Toshihiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Ohu University
Trophectoderm regeneration to support full-term development in the inner cell mass isolated from bovine blastocyst
- Principal Investigator
  
  Kawahara Manabu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Hokkaido University
Analysis of fetal-maternal interaction in hypoxic environmentPrincipal Investigator
- Principal Investigator
  
  Bai Hanako
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Animal production science
- Research Institution
  Hokkaido University

All 2024 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation Patent

[Journal Article] 着床期子宮内インターフェロンと誘導性遺伝子2024
- Author(s)
  唄花子、川原学、高橋昌志
- Journal Title
  
  細胞
  
  Volume: 56 Pages: 196-198
- Data Source
  KAKENHI-PROJECT-22K05964
[Journal Article] IFNT stimulates lysosomal function via type I IFN signaling pathway in pregnant bovine leukocytes2023
- Author(s)
  Talukder Md Abdus Shabur, Balboula Ahmed Zaky, Bai Hanako, Kawahara Manabu, Kimura Koji, Takahashi Masashi
- Journal Title
  
  Reproduction
  
  Volume: 166 Issue: 6 Pages: 411-421
- DOI
  10.1530/rep-23-0098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K05964
[Journal Article] Synergistic effect of standardized extract of Asparagus officinalis stem and heat shock on progesterone synthesis with lipid droplets and mitochondrial function in bovine granulosa cells2023
- Author(s)
  Ho Khoi Thieu, Balboula Ahmed Zaky, Homma Kohei, Takanari Jun, Bai Hanako, Kawahara Manabu, Thi Kim Nguyen Khang, Takahashi Masashi
- Journal Title
  
  The Journal of Steroid Biochemistry and Molecular Biology
  
  Volume: 225 Pages: 106181-106181
- DOI
  10.1016/j.jsbmb.2022.106181
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05964, KAKENHI-PROJECT-21H02336
[Journal Article] 子宮内インターフェロンと誘導性遺伝子2023
- Author(s)
  唄花子、川原学、高橋昌志
- Journal Title
  
  Medical Science Digest.
  
  Volume: 49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K05964
[Journal Article] Expression of NFIL3 and CEBPA regulated by IFNT induced-PGE2 in bovine endometrial stromal cells during the pre-implantation period2023
- Author(s)
  Rulan Bai, Kazuya Kusama, Yuta Matsuno, Hanako Bai, Toshihiro Sakurai, Koji Kimura, Kazuhiko Imakawa
- Journal Title
  
  Frontiers in Endocrinology
  
  Volume: 14 Pages: 1075030-1075030
- DOI
  10.3389/fendo.2023.1075030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03133, KAKENHI-PROJECT-23K23767, KAKENHI-PROJECT-22K05964
[Journal Article] Dual barrier system against xenomitochondrial contamination in mouse embryos2023
- Author(s)
  Komatsu Masaya, Takuma Hikaru, Imai Shun, Yamane Maiko, Takahashi Masashi, Ikegawa Takuto, Bai Hanako, Ogawa Hidehiko, Kawahara Manabu
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 23058-23058
- DOI
  10.1038/s41598-023-50444-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K05964
[Journal Article] Analysis of sequential ruminal temperature sensor data from dairy cows to identify cow subgroups by clustering and predict calving through supervised machine learning2023
- Author(s)
  FURUKAWA Eri, YANAGAWA Yojiro, MATSUZAKI Akira, KIM Heejin, BAI Hanako, TAKAHASHI Masashi, KATAGIRI Seiji, HIGAKI Shogo
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 69 Issue: 2 Pages: 103-108
- DOI
  10.1262/jrd.2022-107
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Data Source
  KAKENHI-PROJECT-22K05964
[Journal Article] Identification of menaquinone-4 (vitamin K2) target genes in bovine endometrial epithelial cells in?vitro2023
- Author(s)
  Bai Hanako, Kawahara Manabu, Takahashi Masashi
- Journal Title
  
  Theriogenology
  
  Volume: 198 Pages: 183-193
- DOI
  10.1016/j.theriogenology.2022.12.033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K05964, KAKENHI-PROJECT-21H02336
[Journal Article] Cattle production by intracytoplasmic sperm injection into oocytes vitrified after ovum pick-up2022
- Author(s)
  Kagawa Shinjiro、Hiraizumi Shingo、Bai Hanako、Takahashi Masashi、Kawahara Manabu
- Journal Title
  
  Theriogenology
  
  Volume: 185 Pages: 121-126
- DOI
  10.1016/j.theriogenology.2022.03.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02336, KAKENHI-PROJECT-22K05964
[Journal Article] Generation of viable calves derived from developmentally mature blastocysts produced by on-gel culture2022
- Author(s)
  SAITO Shun、AKIZAWA Hiroki、FURUKAWA Eri、YANAGAWA Yojiro、BAI Hanako、TAKAHASHI Masashi、KAWAHARA Manabu
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 68 Issue: 5 Pages: 330-334
- DOI
  10.1262/jrd.2022-054
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02336
[Journal Article] Characterization of Serum Metabolome and Proteome Profiles Identifies SNX5 Specific for Pregnancy Failure in Holstein Heifers2022
- Author(s)
  Kusama Kazuya、Bai Rulan、Matsuno Yuta、Ideta Atsushi、Sakurai Toshihiro、Nagaoka Kentaro、Hori Masatoshi、Imakawa Kazuhiko
- Journal Title
  
  Life
  
  Volume: 12 Issue: 2 Pages: 309-309
- DOI
  10.3390/life12020309
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K14965, KAKENHI-PROJECT-19H03111, KAKENHI-PROJECT-20H03133, KAKENHI-PROJECT-19H03125, KAKENHI-PROJECT-23K23767
[Journal Article] Effect of E-64 Supplementation during In Vitro Maturation on the Developmental Competence of Bovine OPU-Derived Oocytes2022
- Author(s)
  Balboula Ahmed Z, Aboelenain Mansour, Sakatani Miki, Yamanaka Ken-Ichi, Bai Hanako, Shirozu Takahiro, Kawahara Manabu, Hegab Abd Elraouf O, Zaabel Samy M, Takahashi Masashi
- Journal Title
  
  Genes
  
  Volume: 13 Issue: 2 Pages: 324-324
- DOI
  10.3390/genes13020324
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15644, KAKENHI-PROJECT-20K06378
[Journal Article] Effects of dietary vitamin K3 supplementation on vitamin K1 and K2 (menaquinone) dynamics in dairy cows2022
- Author(s)
  Bai Hanako, Arai Hikoji, Ikuta Kentarou, Ishikawa Sho, Ohtani Yoshihisa, Iwashita Kunihiro, Okada Nao, Shirakawa Hitoshi, Komai Michio, Terada Fuminori, Obara Yoshiaki
- Journal Title
  
  Animal Science Journal
  
  Volume: 93 Issue: 1
- DOI
  10.1111/asj.13680
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15644, KAKENHI-PROJECT-20H02928
[Journal Article] Environmental factors affecting the conception rates of nulliparous and primiparous dairy cattle2022
- Author(s)
  Ukita Haruka、Yamazaki Takeshi、Yamaguchi Satoshi、Abe Hayato、Baba Toshimi、Bai Hanako、Takahashi Masashi、Kawahara Manabu
- Journal Title
  
  Journal of Dairy Science
  
  Volume: －
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02336
[Journal Article] Zona pellucida removal by acid Tyrode’s solution affects pre- and post-implantation development and gene expression in mouse embryos2022
- Author(s)
  Fan Weihong、Huang Tengda、Wu Tian、Bai Hanako、Kawahara Manabu、Takahashi Masashi
- Journal Title
  
  Biology of Reproduction
  
  Volume: -
- DOI
  10.1093/biolre/ioac155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02336
[Journal Article] Recent progress of interferon-tau research and potential direction beyond pregnancy recognition2022
- Author(s)
  BAI Hanako、KAWAHARA Manabu、TAKAHASHI Masashi、IMAKAWA Kazuhiko
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 68 Issue: 5 Pages: 299-306
- DOI
  10.1262/jrd.2022-061
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K05964
[Journal Article] Cell-cycle dependent GATA2 subcellular localization in mouse 2-cell embryos2021
- Author(s)
  Komatsu Masaya, Tsukahara Hayato, Bai Hanako, Takahashi Masashi, Wakai Takuya, Kawahara Manabu
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 584 Pages: 1-6
- DOI
  10.1016/j.bbrc.2021.10.077
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15644, KAKENHI-PROJECT-21H02336, KAKENHI-PROJECT-20K06627
[Journal Article] Heat stress induces oxidative stress and activates the KEAP1-NFE2L2-ARE pathway in bovine endometrial epithelial cells2021
- Author(s)
  Murata Hirona, Kunii Hiroki ,Kusama Kazuya, Sakurai Toshihiro, Bai Hanako、Kawahara Manabu、Takahashi Masashi
- Journal Title
  
  Biology of Reproduction
  
  Volume: 105 Issue: 5 Pages: 1114-1125
- DOI
  10.1093/biolre/ioab143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15644, KAKENHI-PROJECT-19H03111, KAKENHI-PROJECT-21H02336
[Journal Article] Deciphering two rounds of cell lineage segregations during bovine preimplantation development2021
- Author(s)
  Akizawa Hiroki, Saito Shun, Kohri Nanami, Furukawa Eri, Hayashi Yoshihiro, Bai Hanako, Nagano Masashi, Yanagawa Yojiro, Tsukahara Hayato, Takahashi Masashi, Kagawa Shinjiro, Kawahara‐Miki Ryouka, Kobayashi Hisato、Kono Tomohiro、Kawahara Manabu
- Journal Title
  
  The FASEB Journal
  
  Volume: 35 Issue: 10
- DOI
  10.1096/fj.202002762rr
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15644, KAKENHI-PROJECT-21H02336, KAKENHI-PROJECT-23K21282
[Journal Article] Requirement for expression of WW domain containing transcription regulator 1 in bovine trophectoderm development2021
- Author(s)
  Saito Shun、Yamamura Shota、Kohri Nanami、Bai Hanako、Takahashi Masashi、Kawahara Manabu
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 555 Pages: 140-146
- DOI
  10.1016/j.bbrc.2021.03.112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02321, KAKENHI-PROJECT-20K15644, KAKENHI-PROJECT-21H02336
[Journal Article] Loop-mediated isothermal amplification (LAMP) and machine learning application for early pregnancy detection using bovine vaginal mucosal membrane2021
- Author(s)
  Kunii Hiroki, Kubo Tomoaki, Asaoka Natsuki, Balboula Ahmed Z, Hamaguchi Yu, Shimasaki Tomoya, Bai Hanako, Kawahara Manabu, Kobayashi Hisato, Ogawa Hidehiko, Takahashi Masashi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 569 Pages: 179-186
- DOI
  10.1016/j.bbrc.2021.07.015
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15644, KAKENHI-PROJECT-21H02336, KAKENHI-PROJECT-20J11776, KAKENHI-PROJECT-23K21282
[Journal Article] The use of a two-step removal protocol and optimized culture conditions improve development and quality of zona free mouse embryos2021
- Author(s)
  Fan Weihong, Homma Misato, Xu Renliang, Kunii Hiroki, Bai Hanako, Kawahara Manabu, Kawaguchi Toshikazu, Takahashi Masashi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 577 Pages: 116-123
- DOI
  10.1016/j.bbrc.2021.09.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15644, KAKENHI-PROJECT-21H02336
[Journal Article] A standardized extract of Asparagus officinalis stem improves HSP70-mediated redox balance and cell functions in bovine cumulus-granulosa cells2021
- Author(s)
  Ho Khoi Thieu, Homma Kohei, Takanari Jun, Bai Hanako, Kawahara Manabu, Nguyen Khang Thi Kim, Takahashi Masashi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 18175-18175
- DOI
  10.1038/s41598-021-97632-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15644, KAKENHI-PROJECT-21H02336
[Journal Article] Mitochondrial maturation in the trophectoderm and inner cell mass regions of bovine blastocysts2021
- Author(s)
  Hayashi Yoshihiro, Saito Shun, Bai Hanako, Takahashi Masashi, Kawahara Manabu
- Journal Title
  
  Theriogenology
  
  Volume: 175 Pages: 69-76
- DOI
  10.1016/j.theriogenology.2021.08.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15644, KAKENHI-PROJECT-21H02336
[Journal Article] Effect of summer heat stress on gene expression in bovine uterine endometrial tissues2020
- Author(s)
  Bai Hanako, Ukita Haruka, Kawahara Manabu, Mitani Tomohiro, Furukawa Eri, Yanagawa Yojiro, Yabuuchi Naoto, Kim Heejin, Takahashi Masashi
- Journal Title
  
  Animal Science Journal
  
  Volume: 91 Issue: 1 Pages: 1-9
- DOI
  10.1111/asj.13474
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15644, KAKENHI-PROJECT-18H02321, KAKENHI-PROJECT-19H03099
[Journal Article] Inverse relationship between autophagy and CTSK is related to bovine embryo quality2020
- Author(s)
  Balboula Ahmed Z, Aboelenain Mansour, Li Jianye, Bai Hanako, Kawahara Manabu, Abdel-Ghani Mohammed A, Takahashi Masashi
- Journal Title
  
  Reproduction
  
  Volume: 159 Issue: 6 Pages: 757-766
- DOI
  10.1530/rep-20-0036
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15644, KAKENHI-PROJECT-19H03099
[Journal Article] Short communication: Menaquinone-4 (vitamin K2) induces proliferation responses in bovine peripheral blood mononuclear cells2020
- Author(s)
  Bai H.、Hiura H.、Obara Y.、Kawahara M.、Takahashi M.
- Journal Title
  
  Journal of Dairy Science
  
  Volume: 103 Issue: 8 Pages: 7531-7534
- DOI
  10.3168/jds.2019-17987
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09215, KAKENHI-PROJECT-20K15644, KAKENHI-PROJECT-19H03099
[Journal Article] Yes-associated protein 1 translocation through actin cytoskeleton organization in trophectoderm cells2020
- Author(s)
  Yamamura Shota, Goda Nanami, Akizawa Hiroki, Kohri Nanami, Balboula Ahmed Z, Kobayashi Ken, Bai Hanako, Takahashi Masashi, Kawahara Manabu
- Journal Title
  
  Developmental Biology
  
  Volume: 468 Issue: 1-2 Pages: 14-25
- DOI
  10.1016/j.ydbio.2020.09.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15644, KAKENHI-PROJECT-18H02321, KAKENHI-PROJECT-19H03099
[Journal Article] The role of RHOA signaling in trophectoderm cell-fate decision in cattle2020
- Author(s)
  Kohri Nanam, Akizawa Hiroki, Iisaka Sakie, Bai Hanako, Takahashi Masashi, Kawahara Manabu
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 528 Issue: 4 Pages: 713-718
- DOI
  10.1016/j.bbrc.2020.05.210
- NAID
  120007126837
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15644, KAKENHI-PROJECT-18H02321, KAKENHI-PROJECT-19H03099
[Journal Article] Cluster analysis to evaluate disease risk in periparturient dairy cattle2020
- Author(s)
  Ishikawa Sho, Ikuta Kentaro, Obara Yoshiaki, Oka Akio, Otani Yoshihisa, Takahashi Yuji, Bai Hanako, Terada Fuminori, Kushibiki Shiro
- Journal Title
  
  Animal Science Journal
  
  Volume: 91 Issue: 1
- DOI
  10.1111/asj.13442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15644
[Journal Article] Trophectoderm regeneration to support full-term development in the inner cell mass isolated from bovine blastocyst2019
- Author(s)
  Kohri Nanami、Akizawa Hiroki、Iisaka Sakie、Bai Hanako、Yanagawa Yojiro、Takahashi Masashi、Komatsu Masaya、Kawai Masahito、Nagano Masashi、Kawahara Manabu
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 294 Issue: 50 Pages: 19209-19223
- DOI
  10.1074/jbc.ra119.010746
- NAID
  120006940625
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02321
[Journal Article] Effects of use of conventional and sexed semen on the conception rate in heifers: A comparison study2019
- Author(s)
  Oikawa Kohei、Yamazaki Takeshi、Yamaguchi Satoshi、Abe Hayato、Bai Hanako、Takahashi Masashi、Kawahara Manabu
- Journal Title
  
  Theriogenology
  
  Volume: 135 Pages: 33-37
- DOI
  10.1016/j.theriogenology.2019.06.012
- NAID
  120006882075
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02321, KAKENHI-PROJECT-19H03099
[Journal Article] Evaluation of the immune status of peripheral blood monocytes from dairy cows during the periparturition period.2019
- Author(s)
  Bai H, Talukder MAS, Kunii H, Itoh T, Kawahara M, Takahashi M.
- Journal Title
  
  Journal of Reproduction and Development
  
  Volume: 65
- NAID
  130007689002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15357
[Journal Article] Overgrowth of mice generated from postovulatory aged oocyte spindles.2019
- Author(s)
  Shiina K, Komatsu M, Yokoi F, Bai H, Takahashi T, Kawahara M.
- Journal Title
  
  FASEB BioAdvances
  
  Volume: 印刷中 Issue: 7 Pages: 1-11
- DOI
  10.1096/fba.2019-00005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15357, KAKENHI-PROJECT-18H02321
[Journal Article] Pregnancy-induced expression of interferon-stimulated genes in cervical and vaginal mucosal membrane.2018
- Author(s)
  Kunii H, Koyama K, Ito T, Suzuki T, Balboula AZ, Shirozu T, Bai H, Nagano M, Kawahara M, Takahashi M.
- Journal Title
  
  Journal of Dairy Science
  
  Volume: 101 Issue: 9 Pages: 8396-8400
- DOI
  10.3168/jds.2017-14251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15357
[Journal Article] Reciprocal regulation of TEAD4 and CCN2 for the trophectoderm development of the bovine blastocyst.2018
- Author(s)
  Hiroki Akizawa, Ken Kobayashi , Hanako Bai, Masashi Takahashi, Shinjiro Kagawa, Hiroaki Nagatomo, Manabu Kawahara
- Journal Title
  
  Reproduction
  
  Volume: 印刷中 Issue: 6 Pages: 563-571
- DOI
  10.1530/rep-18-0043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17J01122, KAKENHI-PROJECT-16K14587, KAKENHI-PROJECT-17K15359, KAKENHI-PROJECT-17K15357
[Journal Article] Identification and expression analysis of cDNA encoding insulin-like growth factor 2 in horses2018
- Author(s)
  Kikuchi K, Sasaki K, Akizawa H, Tsukahara H, Bai H, Takahashi M, Nambo Y, Hata H, Kawahara M.
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 64 Issue: 1 Pages: 57-64
- DOI
  10.1262/jrd.2017-124
- NAID
  130006405024
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15357, KAKENHI-PROJECT-17J01122, KAKENHI-PROJECT-16K14587, KAKENHI-PROJECT-15H04579
[Journal Article] Maternal recognition and establishment of pregnancy in ruminants2018
- Author(s)
  Bai H, Kawahara M, Takahashi M
- Journal Title
  
  Reviews on Animal Nutrition and Metabolism
  
  Volume: 62 Pages: 19-25
- NAID
  40021510403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15357
[Journal Article] Significance of CCN2 expression in bovine preimplantation development2018
- Author(s)
  Akizawa Hiroki、Yanagawa Yojiro、Nagano Masashi、Bai Hanako、Takahashi Masashi、Kawahara Manabu
- Journal Title
  
  Animal Science Journal
  
  Volume: 90 Issue: 1 Pages: 49-54
- DOI
  10.1111/asj.13126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17J01122, KAKENHI-PROJECT-17K15357, KAKENHI-PROJECT-18H02321
[Journal Article] Involvement of interferon-tau in the induction of apoptotic, pyroptotic, and autophagic cell death-related signaling pathways in the bovine uterine endometrium during early pregnancy2018
- Author(s)
  Suzuki T, Sakumoto R, Hayashi K, Ogiso T, Kunii H, Shirozu T, Kim SW, Bai H, Kawahara M, Kimura K, Takahashi M.
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 64 Issue: 6 Pages: 495-502
- DOI
  10.1262/jrd.2018-063
- NAID
  130007530502
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15357
[Journal Article] Evaluating the electrical impedance and mucus-related gene expression of uterine endometrial tissues in mares2018
- Author(s)
  Kikuchi K, Kozai K, Hojo T, Sakatani M, Okuda K, Bai H, Kawahara M, Takahashi M.
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 64 Issue: 2 Pages: 193-197
- DOI
  10.1262/jrd.2017-128
- NAID
  130006699687
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15357, KAKENHI-PROJECT-26292136, KAKENHI-PROJECT-16K14587
[Journal Article] Enhancement of sperm motility and viability by turmeric by-product dietary supplementation in roosters2017
- Author(s)
  Yan W, Kanno C, Oshima E, Kuzuma Y, Kim SW, Bai H, Takahashi M, Yanagawa Y, Nagano M, Wakamatsu JI, Kawahara M.
- Journal Title
  
  Animal reproduction science.
  
  Volume: 185 Pages: 195-204
- DOI
  10.1016/j.anireprosci.2017.08.021
- NAID
  120006523735
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15357, KAKENHI-PROJECT-16K14587
[Journal Article] Novel endogenous retrovirus-derived transcript expressed in the bovine placenta is regulated by WNT signaling.2017
- Author(s)
  Sakurai T, Nakagawa S, Bai H, Bai R, Kusama K, Ideta A, Aoyagi Y, Kaneko K, Iga K, Yasuda J, Miyazawa T, Imakawa K.
- Journal Title
  
  Biochemical Journal
  
  Volume: 474 Issue: 20 Pages: 3499-3512
- DOI
  10.1042/bcj20170531
- NAID
  120006649525
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15357, KAKENHI-PROJECT-16H02584, KAKENHI-PROJECT-16F16403, KAKENHI-PROJECT-15K07697, KAKENHI-PROJECT-16K21386
[Patent] ウシ胚の体外培養方法、ウシ胚、及びウシの生産方法2022
- Inventor(s)
  川原　学、秋沢　宏紀、高橋　昌志、唄　花子
- Industrial Property Rights Holder
  川原　学、秋沢　宏紀、高橋　昌志、唄　花子
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-21H02336
[Patent] 内部細胞塊から腔再形成胚を作製する方法および腔再形成胚を用いたウシ個体の作出方法2019
- Inventor(s)
  川原学、郡七海、高橋昌志、唄花子
- Industrial Property Rights Holder
  川原学、郡七海、高橋昌志、唄花子
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-172732
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18H02321
[Presentation] ウシ胚内部細胞塊における転写共役因子YAP1の細胞内局在とその意義2023
- Author(s)
  齋藤隼、西山洸司、柳川洋二郎、唄花子、高橋昌志、川原学
- Organizer
  第116回日本繁殖生物学会神戸大会
- Data Source
  KAKENHI-PROJECT-22K05964
[Presentation] マウス胚におけるHippo経路関連因子Nf2およびLats2の局在解析2023
- Author(s)
  鈴木雅、合田菜な未、伊藤維、齋藤隼、唄花子、高橋昌志、若井拓哉、川原学
- Organizer
  第116回日本繁殖生物学会神戸大会
- Data Source
  KAKENHI-PROJECT-22K05964
[Presentation] ウシ子宮内膜上皮細胞における暑熱負荷培養時のNFE2L2の標的遺伝子の探索.2022
- Author(s)
  唄花子, 川原学, 高橋昌志.
- Organizer
  日本繁殖生物学会 (東京都東京大学)
- Data Source
  KAKENHI-PROJECT-21H02336
[Presentation] ウシ卵子成熟および発生における熱ショック非依存的なHSP70発現誘導と酸化ストレスに及ぼすEASの影響.2022
- Author(s)
  楠野莉奈子, Ho Khoi, 本間康平, 高成準, 唄花子, 川原学, 高橋昌志.
- Organizer
  日本畜産学会 (神奈川県東京農業大学)
- Data Source
  KAKENHI-PROJECT-21H02336
[Presentation] 妊娠認識と着床過程の研究2022
- Author(s)
  唄花子
- Organizer
  令和4年度日本農芸化学会北海道支部学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-22K05964
[Presentation] Gene expression changes in trophoblast cells after the blastocyst stage in cattle.2022
- Author(s)
  Akizawa H., Bai H., Takahashi M. and Kawahara M.
- Organizer
  International Embryo Technology Society 48th Annual Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02336
[Presentation] ウシ子宮内膜上皮細胞における暑熱負荷培養時のNFE2L2標的遺伝子の探索2022
- Author(s)
  唄花子、川原学、高橋昌志
- Organizer
  第115回日本繁殖生物学会大会
- Data Source
  KAKENHI-PROJECT-22K05964
[Presentation] ウシ子宮内膜上皮細胞における暑熱負荷培養時の酸化ストレス応答経路の検証2021
- Author(s)
  唄花子，國井宏樹，川原学，高橋昌志
- Organizer
  第114回日本繁殖生物学会
- Data Source
  KAKENHI-PROJECT-20K15644
[Presentation] 腟底部発現変動遺伝子を用いたRT-LAMP法および機械学習によるウシ簡易迅速妊娠判定モデルの検討.2021
- Author(s)
  國井宏樹，窪友瑛，浅岡那月，嶋崎知哉，唄花子，川原学，高橋昌志.
- Organizer
  日本繁殖生物学会 (京都府京都大学)
- Data Source
  KAKENHI-PROJECT-21H02336
[Presentation] Effect of EAS on P4 production pathway of bovine CG cells in relation with HSP70.2021
- Author(s)
  Khoi Thieu HO, Kohei HOMMA, Jun TAKANARI, Hanako BAI, Manabu KAWAHARA, Kim Khang NGUYEN THI, Masashi TAKAHASHI.
- Organizer
  日本繁殖生物学会 (京都府京都大学)
- Data Source
  KAKENHI-PROJECT-21H02336
[Presentation] Effect of two-step combined zona pellucida removal on developmental competence of mouse embryos.2021
- Author(s)
  Weihong Fan, Hanako Bai, Manabu Kawahara, Masashi Takahashi.
- Organizer
  日本畜産学会 (宮城県東北大学)
- Data Source
  KAKENHI-PROJECT-21H02336
[Presentation] Effect of EAS on HSP70 related progesterone synthesis in bovine cumulusgranulosa cells.2021
- Author(s)
  Khoi Thieu HO, Kohei HOMMA, Jun TAKANARI, Tomohiro MITANI, Hanako BAI, Manabu KAWAHARA, Kim Khang Thi NGUYEN, Masashi TAKAHASHI.
- Organizer
  日本畜産学会、九州大学(福岡県)
- Data Source
  KAKENHI-PROJECT-18H02321
[Presentation] ホルスタイン種初産牛の人工授精受胎率に及ぼす環境要因の解析2021
- Author(s)
  宇喜多遥、山崎武志、山口諭、阿部隼人、馬場俊見、唄花子、高橋昌志、川原学
- Organizer
  第129回日本畜産学会
- Data Source
  KAKENHI-PROJECT-20K15644
[Presentation] ウシ子宮内膜上皮細胞における暑熱負荷培養時の酸化ストレス応答経路の検証.2021
- Author(s)
  唄花子，國井宏樹，川原学，高橋昌志.
- Organizer
  日本繁殖生物学会 (京都府京都大学)
- Data Source
  KAKENHI-PROJECT-21H02336
[Presentation] Effect of zona pellucida on early development and gene expression in mouse embryos.2021
- Author(s)
  Weihong FAN, Hanako BAI, Manabu KAWAHARA, Masashi TAKAHASHI.
- Organizer
  日本畜産学会、九州大学(福岡県)
- Data Source
  KAKENHI-PROJECT-18H02321
[Presentation] Effect of EAS on post freezing viability of heat stressed bovine cumulus granulosa cells in relation with redox balance.2021
- Author(s)
  Khoi Thieu Ho, Kohei Homma, Jun Takanari, Hanako Bai, Manabu Kawahara, Kim Khang Nguyen Thi, Masashi Takahashi.
- Organizer
  日本畜産学会 (宮城県東北大学)
- Data Source
  KAKENHI-PROJECT-21H02336
[Presentation] ホルスタイン種初産牛の人工授精受胎率に及ぼす環境要因の解析.2021
- Author(s)
  宇喜多遥, 山崎武志, 山口諭, 阿部隼人, 馬場俊見, 唄花子, 高橋昌志, 川原学.
- Organizer
  日本畜産学会 (宮城県東北大学)
- Data Source
  KAKENHI-PROJECT-21H02336
[Presentation] 第二胃内留置型自動体温測定器で測定したホルスタイン種経産牛の分娩前1週間の体温変化と分娩時間帯の関係2021
- Author(s)
  古川瑛理、高橋昌志、松崎明、唄花子、永野昌志、片桐成二、栁川洋二郎
- Organizer
  第129回日本畜産学会
- Data Source
  KAKENHI-PROJECT-20K15644
[Presentation] 腟底部発現変動遺伝子を用いたRT-LAMP法および機械学習によるウシ簡易迅速妊娠判定モデルの検討2021
- Author(s)
  國井宏樹，窪友瑛，浅岡那月，嶋崎知哉, 唄花子，川原学，高橋昌志
- Organizer
  第114回日本繁殖生物学会
- Data Source
  KAKENHI-PROJECT-20K15644
[Presentation] Effect of two-step combined zona pellucida removal on developmental competence of mouse embryos2021
- Author(s)
  Weihong Fan, Hanako Bai, Manabu Kawahara, Masashi Takahashi
- Organizer
  第129回日本畜産学会
- Data Source
  KAKENHI-PROJECT-20K15644
[Presentation] Effect of EAS on post freezing viability of heat stressed bovine cumulus granulosa cells in relation with redox balance2021
- Author(s)
  Khoi Thieu Ho, Kohei Homma, Jun Takanari, Hanako Bai, Manabu Kawahara, Kim Khang Nguyen Thi , Masashi Takahashi
- Organizer
  第129回日本畜産学会
- Data Source
  KAKENHI-PROJECT-20K15644
[Presentation] Effect of EAS on P4 production pathway of bovine CG cells in relation with HSP702021
- Author(s)
  Khoi Thieu Ho, Kohei Homma, Jun Takanari, Hanako Bai, Manabu Kawahara, Kim Khang Nguyen Thi, Masashi Takahashi
- Organizer
  第114回日本繁殖生物学会
- Data Source
  KAKENHI-PROJECT-20K15644
[Presentation] Species-specific dynamics of mitochondrial content within an embryo during preimplantation development in mice and cattle.2020
- Author(s)
  Komatsu M., Yokoi F., Imai S., Yamane M., Bai H., Takahashi M., and Kawahara M.
- Organizer
  Fertility Conference and Exhibition 2020, Edinburgh (UK).
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02321
[Presentation] 乳牛の分娩前後における末梢血単核球のストレスおよび免疫関連因子の解析.2018
- Author(s)
  唄花子, Shabur Md Abdus TALUKDER, 国井宏樹, 伊藤月乃, 川原学, 高橋昌志.
- Organizer
  日本繁殖生物学会 (長野県上田市)
- Data Source
  KAKENHI-PROJECT-18H02321
[Presentation] 反芻動物の妊娠認識と成立機構.2018
- Author(s)
  唄花子、川原学、高橋昌志.
- Organizer
  家畜栄養生理研究会
- Data Source
  KAKENHI-PROJECT-17K15357
[Presentation] 性選別精液による乳牛人工授精の受胎率に及ぼす環境要因の影響.2018
- Author(s)
  及川康平, 山崎武志, 山口諭, 阿部隼人, 唄花子, 高橋昌志, 川原学.
- Organizer
  日本繁殖生物学会 (長野県上田市)
- Data Source
  KAKENHI-PROJECT-18H02321
[Presentation] ウシ子宮内膜上皮細胞を用いた暑熱負荷培養およびインターフェロン・タウ応答性の検証.2018
- Author(s)
  小松正明, 鈴木惇文, 国井宏樹, 川原学, 木村康二, 高橋昌志, 唄花子.
- Organizer
  日本繁殖生物学会 (長野県上田市)
- Data Source
  KAKENHI-PROJECT-18H02321
[Presentation] 乳牛の分娩前後における末梢血単核球のストレスおよび免疫関連因子の解析2018
- Author(s)
  唄花子，Shabur Md Abdus Talukder，国井宏樹，伊藤月乃，川原学，高橋昌志
- Organizer
  日本繁殖生物学会
- Data Source
  KAKENHI-PROJECT-17K15357
[Presentation] Hippo経路標的分子TAZ 遺伝子の発現抑制がウシ初期胚に及ぼす影響.2018
- Author(s)
  山村頌太, 郡七海, 秋沢宏紀, 唄花子, 高橋昌志, 川原学.
- Organizer
  日本繁殖生物学会 (長野県上田市)
- Data Source
  KAKENHI-PROJECT-18H02321
[Presentation] ウシ子宮内膜上皮細胞を用いた暑熱負荷培養およびインターフェロン・タウ応答性の検証2018
- Author(s)
  小松正明，鈴木惇文，国井宏樹，川原学，木村康二，高橋昌志，唄花子
- Organizer
  日本繁殖生物学会
- Data Source
  KAKENHI-PROJECT-17K15357

1. Kawahara Manabu (70468700)

# of Collaborated Projects: 3 results

# of Collaborated Products: 22 results
2. Sakurai Toshihiro (70568253)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 草間和哉 (30579149)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 柳川洋二郎 (20609656)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 永野昌志 (70312402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 加川真二朗 (80770643)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 鈴木裕 (10793846)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 樋浦仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 松野雄太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Bai Hanako 唄 花子

Research Projects

Research Products

Co-Researchers

インターフェロン誘導性遺伝子の着床期血管新生作用の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ウシ胚気液界面培養法の改良による胚盤葉上層形成機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

子宮環境構築のための新規インターフェロン誘導性遺伝子の機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of differentiation mechanism of bovine trophoblast cells into placental component cells.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Maintenance of trophectoderm in bovine vitrified embryos based on elucidation of regulatory mechanism of early embryonic differentiation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification and analysis of interferon stimulated genes in the uterusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Intrauterine environment during implantation in bovine pregnancy.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Trophectoderm regeneration to support full-term development in the inner cell mass isolated from bovine blastocyst

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of fetal-maternal interaction in hypoxic environmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 着床期子宮内インターフェロンと誘導性遺伝子2024

Author(s)

Journal Title

Data Source

[Journal Article] IFNT stimulates lysosomal function via type I IFN signaling pathway in pregnant bovine leukocytes2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synergistic effect of standardized extract of Asparagus officinalis stem and heat shock on progesterone synthesis with lipid droplets and mitochondrial function in bovine granulosa cells2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 子宮内インターフェロンと誘導性遺伝子2023

Author(s)

Journal Title

Data Source

[Journal Article] Expression of NFIL3 and CEBPA regulated by IFNT induced-PGE2 in bovine endometrial stromal cells during the pre-implantation period2023

Author(s)

Journal Title

DOI

Bai Hanako 唄花子