Masanori Sawamura 澤村正典

Researcher Number	60852423
Other IDs
Affiliation (based on the past Project Information) *help	2023 – 2024: 京都大学, 医学研究科, 助教 2023: 京都大学, 医学研究科, 特定病院助教 2020 – 2022: 京都大学, 医学研究科, 特定助教 2020: 京都大学, 医学研究科, 特定病院助教 2019: 京都大学, 医学研究科, 医員
Review Section/Research Field	Principal Investigator Basic Section 51030:Pathophysiologic neuroscience-related / 0704:Neuroscience, brain sciences, and related fields Except Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 90120:Biomaterials-related / Basic Section 51030:Pathophysiologic neuroscience-related
Keywords	Principal Investigator αシヌクレイン / マーモセット / パーキンソン病 / 伝播 / 睡眠脳波 / RBD / 霊長類 Except Principal Investigator 脂質膜 / ゲノム編集 / RNA送達 … More / 神経変性疾患 / 脳内伝播 / 共集合化ナノ粒子 / mRNAデリバリー / Nose-to-Brain / 睡眠障害 / 時差 / 霊長類 / 睡眠覚醒リズム / 生体リズム / イムノセンサ / 抗体様低分子 / 原因タンパク質 / 認知症超早期診断 / パーキンソン病 / 機械学習 / 診断チップ / 統計解析 / アミロイドβ / リポソーム / αシヌクレイン / バイオセンサ / プリオン様タンパク質 / 診断用チップ Less

非ヒト霊長類モデルによるパーキンソン病の認知機能障害の解析Principal Investigator
- Principal Investigator
  
  澤村正典
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Kyoto University
Basic technology of lipid membrane immunosensor for detection of pathogenic protein in blood contributing to ultra-early diagnosis of dementia
- Principal Investigator
  
  野田実
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Kyoto Institute of Technology
Primate neurobiological mechanisms underlying sleep-wake abnormality
- Principal Investigator
  
  岡村均
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Kyoto University
脳内病態伝播拠点標的RNA送達Nose-to-Brainミセル開発と脳神経ゲノム編集治療基盤構築
- Principal Investigator
  
  金沢貴憲
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  The University of Tokushima
  University of Shizuoka
The analysis of prodromal symptom (RBD) using non-human primate model.Principal Investigator
- Principal Investigator
  
  Sawamura Masanori
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Kyoto University
Fundamental study on bioelectronic chip for diagnosis of pathologic conditions based on specific and ultrahighly sensitive detection of prion-like protein
- Principal Investigator
  
  Noda Minoru
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Kyoto Institute of Technology
alpha-synuclein propagation via olfactory pathway in non-human primate modelPrincipal Investigator
- Principal Investigator
  
  Masanori Sawamura
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0704:Neuroscience, brain sciences, and related fields
- Research Institution
  Kyoto University

All 2021 2020

All Journal Article Presentation

[Journal Article] Perampanel Inhibits α-Synuclein Transmission in Parkinson's Disease Models2021
- Author(s)
  Ueda J, Uemura N, Sawamura M, Taguchi T, Ikuno M, Kaji S, Taruno Y, Matsuzawa S, Yamakado H, Takahashi R.
- Journal Title
  
  Mov Disord. 2021 Apr 4. doi: 10.1002/mds.28558. Epub ahead of print. PMID: 33813737.
  
  Volume: 4 Issue: 7 Pages: 28558-28558
- DOI
  10.1002/mds.28558
- NAID
  120007030224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22964, KAKENHI-PROJECT-20H00663, KAKENHI-PROJECT-19K16610
[Journal Article] Rapid Induction of Dopaminergic Neuron Loss Accompanied by Lewy Body-Like Inclusions in A53T BAC-SNCA Transgenic Mice2021
- Author(s)
  Okuda Shinya、Uemura Norihito、Sawamura Masanori、Taguchi Tomoyuki、Ikuno Masashi、Uemura Maiko T.、Yamakado Hodaka、Takahashi Ryosuke
- Journal Title
  
  Neurotherapeutics
  
  Volume: 0 Issue: 1 Pages: 0-0
- DOI
  10.1007/s13311-021-01169-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22964, KAKENHI-PROJECT-20H00663
[Journal Article] Impact of Gba2 on neuronopathic Gaucher’s disease and α-synuclein accumulation in medaka (Oryzias latipes)2021
- Author(s)
  Nakanishi Etsuro、Uemura Norihito、Akiyama Hisako、Kinoshita Masato、Masanori Sawamura、Taruno Yosuke、Yamakado Hodaka、Matsuzawa Shu-ichi、Takeda Shunichi、Hirabayashi Yoshio、Takahashi Ryosuke
- Journal Title
  
  Molecular Brain
  
  Volume: 14 Issue: 1 Pages: 0-0
- DOI
  10.1186/s13041-021-00790-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22964, KAKENHI-PROJECT-20H00663
[Journal Article] BCAS1-positive immature oligodendrocytes are affected by the α-synuclein-induced pathology of multiple system atrophy2020
- Author(s)
  Kaji S, Maki T, Ueda J, Ishimoto T, Inoue Y, Yasuda K, Sawamura M, Hikawa R, Ayaki T, Yamakado H, Takahashi R
- Journal Title
  
  Acta Neuropathol Commun. 2020 Jul 29;8(1):120. doi: 10.1186/s40478-020-00997-4. PMID: 32727582; PMCID: PMC7391509
  
  Volume: 8 Issue: 1 Pages: 120-120
- DOI
  10.1186/s40478-020-00997-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22964, KAKENHI-PROJECT-19K16277, KAKENHI-PROJECT-20H00663
[Presentation] パーキンソン病患者血清中αシヌクレインのリポソーム固定化センサにおける高感度検出の検討2021
- Author(s)
  紙谷虎太郎, 高橋悠矢, Werner Carl Frederik, 澤村正典, 山門穂高, 寒川雅之, 野田実
- Organizer
  応用物理学会2021秋季講演会
- Data Source
  KAKENHI-PROJECT-20H00663
[Presentation] “Benign” amyotrophic lateral sclerosis with slow progression harboring homozygous D92G SOD12021
- Author(s)
  澤村　正典
- Organizer
  7.第62回日本神経学会学術大会 (シンポジウム）
- Data Source
  KAKENHI-PROJECT-20H00663
[Presentation] A highly sensitive and specific detection of biomarker of Parkinson's disease by liposome immobilized cantilever sensor2021
- Author(s)
  Kotaro Kamitani, Masanori Sawamura, Hodaka Yamakado, Masayuki Sohgawa,Minoru Noda
- Organizer
  IEEE EDSK IMFEDK 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00663
[Presentation] リポソームセンシングにおけるNaCl添加によるパーキンソン病原因物質αシヌクレイン凝集体検出感度向上2021
- Author(s)
  紙谷虎太郎, 小林亮子, 澤村正典, 山門穂高, 野田実
- Organizer
  16p-Z21-7. 第68回応用物理学会春季学術講演会. オンライン開催. 3月16-19日 (2021) 11-126
- Data Source
  KAKENHI-PROJECT-20H00663
[Presentation] 非ヒト霊長類におけるα-synuclein嗅覚系伝播とレム睡眠行動異常症2021
- Author(s)
  澤村　正典
- Organizer
  6.第15回パーキンソン病・運動障害疾患コングレス（シンポジウム）
- Data Source
  KAKENHI-PROJECT-20H00663
[Presentation] Au電極上固定化リポソーム表面でのαシヌクレインの凝集・線維化の液中AFM観察2020
- Author(s)
  小林亮子, 澤村正典, 山門穂高, 野田実
- Organizer
  11a-Z12-1, 第81回応用物理学会秋季学術講演会, オンライン開催, 9月8-11日 (2020) 11-225
- Data Source
  KAKENHI-PROJECT-20H00663
[Presentation] A Novel Detection Method of Biomarker Molecule of α-Synuclein for Parkinson Disease by Liposome-Immobilized Cantilever Biosensor Using Self-Templating Phenomena of Prionoid Protein2020
- Author(s)
  Ryoko Kobayashi, Masanori Sawamura, Hodaka Yamakado, Masayuki Sohgawa, Minoru Noda
- Organizer
  G-8-03, The 2020 International Conference on Solid State Devices and Materials (SSDM2020), Virtual Conference, Septmber. 27- 30 (2020) 463-464.（国際学会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00663
[Presentation] リン脂質リポソーム固定化カンチレバーセンサを用いたパーキンソン病患者血清中αシヌクレインの検出2020
- Author(s)
  小林亮子, 澤村正典, 山門穂高, 寒川雅之, 野田実
- Organizer
  9a-Z12-2, 第81回応用物理学会秋季学術講演会, オンライン開催, 9月8日-11日 (2020) 11-075.
- Data Source
  KAKENHI-PROJECT-20H00663
[Presentation] リポソーム固定化カンチレバーセンサを用いたパーキンソン病原因物質αシヌクレイン凝集体の超高感度検出2020
- Author(s)
  小林亮子, 澤村正典, 山門穂高, 寒川雅之, 野田実
- Organizer
  28A3-SS3-6, 第37回「センサ・マイクロマシンと応用システム」シンポジウム, オンライン開催, 10月26-28日 (2020)
- Data Source
  KAKENHI-PROJECT-20H00663
[Presentation] AN ULTRASENSITIVE DETECTION OF AGGREGATED α-SYNUCLEIN AS A BIOMARKER MOLECULE FOR PARKINSON DISEASE BY LIPOSOME-IMMOBILIZED CANTILEVER BIOSENSOR USING SELF-TEMPLATING PHENOMENA OF PRIONOID PROTEIN2020
- Author(s)
  Ryoko Kobayashi, Masanori Sawamura, Hodaka Yamakado, Masayuki Sohgawa, Minoru Noda
- Organizer
  C3L-A-2, MicroTAS 2020, Online Conference, October. 4-9 (2020) 1274.（国際学会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00663

1. Noda Minoru (20294168)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
2. 山門穂高 (10378771)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 島内寿徳 (10335383)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 寒川雅之 (70403128)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
5. 福澤理行 (60293990)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. WERNER Frederik (90791434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 岡村均 (60158813)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 冨永恵子 (60256196)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 郡宏 (80435974)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 角谷寛 (90362516)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 金沢貴憲 (60434015)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 田中浩揮 (60801743)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 山門穗高

# of Collaborated Projects: 0 results

# of Collaborated Products: 12 results

Masanori Sawamura 澤村 正典

Research Projects

Research Products

Co-Researchers

非ヒト霊長類モデルによるパーキンソン病の認知機能障害の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Basic technology of lipid membrane immunosensor for detection of pathogenic protein in blood contributing to ultra-early diagnosis of dementia

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Primate neurobiological mechanisms underlying sleep-wake abnormality

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

脳内病態伝播拠点標的RNA送達Nose-to-Brainミセル開発と脳神経ゲノム編集治療基盤構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The analysis of prodromal symptom (RBD) using non-human primate model.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Fundamental study on bioelectronic chip for diagnosis of pathologic conditions based on specific and ultrahighly sensitive detection of prion-like protein

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

alpha-synuclein propagation via olfactory pathway in non-human primate modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Perampanel Inhibits α-Synuclein Transmission in Parkinson's Disease Models2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Rapid Induction of Dopaminergic Neuron Loss Accompanied by Lewy Body-Like Inclusions in A53T BAC-SNCA Transgenic Mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of Gba2 on neuronopathic Gaucher’s disease and α-synuclein accumulation in medaka (Oryzias latipes)2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] BCAS1-positive immature oligodendrocytes are affected by the α-synuclein-induced pathology of multiple system atrophy2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] パーキンソン病患者血清中αシヌクレインのリポソーム 固定化センサにおける高感度検出の検討2021

Author(s)

Organizer

Data Source

[Presentation] “Benign” amyotrophic lateral sclerosis with slow progression harboring homozygous D92G SOD12021

Author(s)

Organizer

Data Source

[Presentation] A highly sensitive and specific detection of biomarker of Parkinson's disease by liposome immobilized cantilever sensor2021

Author(s)

Organizer

Data Source

[Presentation] リポソームセンシングにおけるNaCl添加によるパーキンソン病原因物質αシヌクレイン凝集体検出感度向上2021

Masanori Sawamura 澤村正典

[Presentation] パーキンソン病患者血清中αシヌクレインのリポソーム固定化センサにおける高感度検出の検討2021