Sada Ryota 佐田遼太

Researcher Number	60869783
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2022 – 2024: 大阪大学, 大学院医学系研究科, 助教 2021: 大阪大学, 医学系研究科, 助教 2020: 大阪大学, 医学系研究科, 特任助教(常勤)
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Basic Section 53010:Gastroenterology-related Except Principal Investigator Basic Section 50010:Tumor biology-related / Basic Section 48040:Medical biochemistry-related
Keywords	Principal Investigator がん微小環境 / 腫瘍微小環境 / 腫瘍免疫 / 肝細胞がん / 肝がん / 膵がん / CKAP4 / DKK1 / HTVi / 免疫逃避 … More / Wntシグナル / 肝細胞癌 / Wnt / 食道がん / 肺がん / FOXM1 … More Except Principal Investigator 肝細胞癌サブタイプ / オルガノイド / CKAP4 / DKK1 / 肝細胞癌 / 細胞内トラフィック / 分泌タンパク質 / 細胞応答 / 細胞膜 / 小胞体 / 受容体 / 小胞輸送 Less

オボアルブミン抗原発現肝細胞がんモデルマウスを用いた抗腫瘍免疫逃避機構の解析Principal Investigator
- Principal Investigator
  
  佐田遼太
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Osaka University
がん微小環境におけるDKK1/3-CKAP4シグナルの機能解明と新規治療法の開発Principal Investigator
- Principal Investigator
  
  佐田遼太
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Osaka University
DKK1/CKAP4シグナルを標的とした肝細胞癌に対する新規抗癌治療の開発
- Principal Investigator
  
  権英寿
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kobe University
Regulation of signal response through a novel DKK1 receptor "CKAP4"
- Principal Investigator
  
  Yamamoto Hideki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Osaka University
Analysis of regulatory mechanisms of DKK1 gene expression and its role in the cancer microenvironment in refractory cancersPrincipal Investigator
- Principal Investigator
  
  Sada Ryota
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Osaka University

All 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] DKK1‐CKAP4 signal axis promotes hepatocellular carcinoma aggressiveness2023
- Author(s)
  Sada Ryota、Iguchi Kosuke、Matsumoto Shinji、Kimura Hirokazu、Zen Yoh、Akita Masayuki、Gon Hidetoshi、Fukumoto Takumi、Kikuchi Akira
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 5 Pages: 2063-2077
- DOI
  10.1111/cas.15743
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15511, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21H04797, KAKENHI-PROJECT-21K19407, KAKENHI-PROJECT-20K16330
[Journal Article] CKAP4 is a potential exosomal biomarker and therapeutic target for lung cancer2023
- Author(s)
  Nagoya Akihiro、Sada Ryota、Kimura Hirokazu、Yamamoto Hideki、Morishita Koichi、Miyoshi Eiji、Morii Eiichi、Shintani Yasushi、Kikuchi Akira
- Journal Title
  
  Translational Lung Cancer Research
  
  Volume: 12 Issue: 3 Pages: 408-426
- DOI
  10.21037/tlcr-22-571
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15511, KAKENHI-PROJECT-21H04797, KAKENHI-PROJECT-21K19407, KAKENHI-PROJECT-20K16330, KAKENHI-PROJECT-20K17746, KAKENHI-PROJECT-20K07311, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-23K24228
[Journal Article] Dickkopf signaling, beyond Wnt-mediated biology2022
- Author(s)
  Kikuchi Akira、Matsumoto Shinji、Sada Ryota
- Journal Title
  
  Seminars in Cell & Developmental Biology
  
  Volume: 125 Pages: 55-65
- DOI
  10.1016/j.semcdb.2021.11.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15511, KAKENHI-PROJECT-21H04797, KAKENHI-PROJECT-21K19407, KAKENHI-PROJECT-20K16330
[Journal Article] The Dickkopf1 and FOXM1 positive feedback loop promotes tumor growth in pancreatic and esophageal cancers2021
- Author(s)
  Kimura Hirokazu、Sada Ryota、Takada Naoki、Harada Akikazu、Doki Yuichiro、Eguchi Hidetoshi、Yamamoto Hideki、Kikuchi Akira
- Journal Title
  
  Oncogene
  
  Volume: 40 Issue: 26 Pages: 4486-4502
- DOI
  10.1038/s41388-021-01860-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07311, KAKENHI-PROJECT-21K19407, KAKENHI-PROJECT-20K16330, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-21H04797
[Presentation] DKK1受容体CKPA4の細胞内輸送制御の解析2023
- Author(s)
  山本英樹、佐田遼太、菊池章
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K07311
[Presentation] 新規DKK1受容体CKPA4の細胞内輸送制御2022
- Author(s)
  山本英樹, 佐田遼太, 菊池章
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K07311
[Presentation] 膵がん・食道扁平上皮がんにおけるDKK1とFOXM1のポジティブフィードバック発現制御を介した腫瘍増殖促進メカニズムの解析 The Dickkopf1 and FOXM1 positive feedback loop promotes tumor growth and associates with poor prognosis of pancreatic and esophageal cancer2022
- Author(s)
  佐田遼太
- Organizer
  第４５回日本分子生物学会総会
- Data Source
  KAKENHI-PROJECT-20K16330
[Presentation] The Dickkopf1 and FOXM1 positive feedback loop promotes tumor growth and associates with poor prognosis of pancreatic and esophageal cancer2022
- Author(s)
  佐田遼太
- Organizer
  第４５回日本分子生物学会総会
- Data Source
  KAKENHI-PROJECT-22K15511
[Presentation] 膵がん・食道扁平上皮がんにおけるDKK1とFOXM1のポジティブフィードバック発現制御を介した腫瘍増殖促進メカニズムの解析2021
- Author(s)
  佐田遼太、木村公一、高田直季、山本英樹、菊池章
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K16330
[Presentation] The Dickkopf1 and FOXM1 positive feedback loop is associated with tumor growth of pancreatic and esophageal cancer2020
- Author(s)
  佐田遼太
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K16330
[Presentation] Dynamic palmitoylation determines membrane microdomain localization of two DKK1 receptors CKAP4 and LRP6, and regulates DKK1 signaling2020
- Author(s)
  山本英樹, 佐田遼太, 木村公一, 菊池章
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K07311

1. Yamamoto Hideki (20372691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. 権英寿 (70648394)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 伊藤智雄 (20301880)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 松本真司 (20572324)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 福本巧 (70379402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Sada Ryota 佐田 遼太

Research Projects

Research Products

Co-Researchers

オボアルブミン抗原発現肝細胞がんモデルマウスを用いた抗腫瘍免疫逃避機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

がん微小環境におけるDKK1/3-CKAP4シグナルの機能解明と新規治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

DKK1/CKAP4シグナルを標的とした肝細胞癌に対する新規抗癌治療の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of signal response through a novel DKK1 receptor "CKAP4"

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of regulatory mechanisms of DKK1 gene expression and its role in the cancer microenvironment in refractory cancersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] DKK1‐CKAP4 signal axis promotes hepatocellular carcinoma aggressiveness2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CKAP4 is a potential exosomal biomarker and therapeutic target for lung cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dickkopf signaling, beyond Wnt-mediated biology2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Dickkopf1 and FOXM1 positive feedback loop promotes tumor growth in pancreatic and esophageal cancers2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] DKK1受容体CKPA4の細胞内輸送制御の解析2023

Author(s)

Organizer

Data Source

[Presentation] 新規DKK1受容体CKPA4の細胞内輸送制御2022

Author(s)

Organizer

Data Source

Author(s)

Organizer

Data Source

[Presentation] The Dickkopf1 and FOXM1 positive feedback loop promotes tumor growth and associates with poor prognosis of pancreatic and esophageal cancer2022

Author(s)

Organizer

Data Source

[Presentation] 膵がん・食道扁平上皮がんにおけるDKK1とFOXM1のポジティブフィードバック発現制御を介した腫瘍増殖促進メカニズムの解析2021

Author(s)

Organizer

Data Source

[Presentation] The Dickkopf1 and FOXM1 positive feedback loop is associated with tumor growth of pancreatic and esophageal cancer2020

Author(s)

Organizer

Data Source

[Presentation] Dynamic palmitoylation determines membrane microdomain localization of two DKK1 receptors CKAP4 and LRP6, and regulates DKK1 signaling2020

Author(s)

Organizer

Sada Ryota 佐田遼太