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YABU Yoshisada  籔 義貞

ORCIDConnect your ORCID iD *help
… Alternative Names

籔 義貞  ヤブ ヨシサダ

藪 義貞  ヤブ ヨシサダ

薮 義貞  ヤブ ヨシサダ

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Researcher Number 70080083
Other IDs
Affiliation (based on the past Project Information) *help 2009 – 2011: Nagoya City University, 大学院・医学研究科, 講師
2007: Nagoya City University, Graduate School of Medical Sciences, Assistant Professor
2006: 名古屋市立大学, 大学院医学研究科, 講師
2005: 名古屋市立大学, 大学院・医学研究科, 講師
1992 – 1993: 名古屋市立大学, 医学部, 講師 … More
1988: 名古屋市立大学, 医学部, 講師
1987: Nagoya City University Medical School, 医学部・医動物学教室, 講師
1986: 名古屋市大, 医学部, 講師 Less
Review Section/Research Field
Principal Investigator
寄生虫学(含医用動物学) / Parasitology (including Sanitary zoology)
Keywords
Principal Investigator
アフリカ睡眠病 / 血流型原虫 / アスコフラノン / hemin / trypsin / metacyclic forms / epimastigote forms / procyclic forms / bloodstream forms / cyclic development … More / Trypanosoma gambiense / 昆虫体内型原虫 / 基本抗原 / 感染型原虫 / 媒介昆虫体内型原虫 / 培養 / 生活環 / ワクチン / Chemotherapy / Derivatives / Mice / Ascofuranone / Cyanide insensitive alternative oxidase / Rhodesian sleeping sickness / 組み換え酵素 / 治療薬 / 原虫 / 血流 / 寄生虫 / ヤギ / アフリカトリパノソーマ / ローデシア睡眼病 / 化学療法 / 誘導体 / マウス / シアン耐性呼吸酵素 / ローデシア睡眠病 / クローニング / 支持細胞を用いない継代培養 / 免疫電顕 / SCIDマウス / 治療薬開発 / 静脈内投与 / 腹腔内投与 / 経口投与 / クリプトスポリジウム … More
Except Principal Investigator
T.vivax(IL1392) / Gallic acid / Trypanosoma / Cytotoxic activity / Anti-Trypanosoma activity / T.bruci gambiense(Wellcome Strain / 走化反応 / 花粉 / Fuchsia hybrida / 細胞致死活性 / 抗トリパノソーマ活性 / T.bruci gambiense(Wellcome株) / T.ivirax(IL1392) Less
  • Research Projects

    (5 results)
  • Research Products

    (20 results)
  • Co-Researchers

    (8 People)
  •  Development of a new chemotherapy for cryptosporidiosisPrincipal Investigator

    • Principal Investigator
      YABU Yoshisada
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Parasitology (including Sanitary zoology)
    • Research Institution
      Nagoya City University
  •  DEVELOPMENT OF CHEMOTHERAPY FOR AFRICAN TRYPANOSOMIASIS USING ASCOFURANONEPrincipal Investigator

    • Principal Investigator
      YABU Yoshisada
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Parasitology (including Sanitary zoology)
    • Research Institution
      Nagoya City University
  •  The chemical attractant against T.virax from pollen grains

    • Principal Investigator
      OGIHARA Yukio
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Nagoya City University
  •  支持細胞を用いないアフリカ睡眠病病原体の培養法の確立Principal Investigator

    • Principal Investigator
      籔 義貞
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Nagoya City University
  •  The complete cyclic development of Trypanosoma gambiense in vitro.Principal Investigator

    • Principal Investigator
      YABU Yoshisada
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      NAGOYA DITY UNIVERSITY MEDICAL SCHOOL

All 2011 2010 2009 2007 2006 2005

All Journal Article Presentation

  • [Journal Article] Differential kinetic activities of glycerol kinase among African trypanosome species : phylogenetic and therapeutic implications2011

    • Author(s)
      Ohashi-Suzuki M, Yabu Y, Ohshima S, Nakamura K, Kido Y, Sakamoto K, Kita K, Ohta N, Suzuki T
    • Journal Title

      J.Vet.Med.Sci.

      Volume: 73 Pages: 615-621

    • NAID

      130000444748

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590467
  • [Journal Article] Purification and kinetic characterization of recombinant alternative oxidase from Trypanosoma brucei brucei2010

    • Author(s)
      Kido Y., Sakamoto, K., Nakamura, K., Harada, M., Suzuki T., Yabu, Y., Saimoto, H., Yamakura F., Ohmori D., Moore A., Harada S., Kita K
    • Journal Title

      Biochim. Biophys. Acta

      Volume: 1797巻 Pages: 443-450

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/20056101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590467
  • [Journal Article] Trypanosome alternative oxidase, a potential therapeutic target for sleeping sickness, is conserved among Trypanosoma brucei subspecies2010

    • Author(s)
      Nakamura K., Fujioka S., Fukumoto S., Inoue N., Sakamoto K., Hirata H., Kido Y., Yabu Y., Suzuki T., Watanabe Y., Saimoto H., Akiyama H., Kita k
    • Journal Title

      Parasit. Int

      Volume: 59巻 Pages: 560-564

    • NAID

      10029826326

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/20688188

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590467
  • [Journal Article] Purification and kinetic characterization of recombinant alternative oxidase from Trypanosoma brucei brucei2010

    • Author(s)
      Kido Y, Sakamoto K, Nakamura K, Harada M, Suzuki T, Yabu Y, Saimoto H, Yamakura F, Ohmori D, Moore A, Harada S, Kita K.
    • Journal Title

      Biochim Biophys Acta 1797

      Pages: 443-450

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590467
  • [Journal Article] TbUNC119 and its binding protein complex are essential for propagation, motility and morphogenesis of Trypanosoma brucei procyclic form cells2010

    • Author(s)
      S.Ohshima, M.Ohashi-Suzuki, Y.Miura, Y.Yabu, N.Okada, N.Ohta, T.Suzuki
    • Journal Title

      PLoS One

      Volume: 5 Pages: 1-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590467
  • [Journal Article] Differential kinetic activities of glycerol kinase among African trypanosomes species : phylogenic and therapeutic implications2010

    • Author(s)
      Ohashi-Suzuki M., Yabu Y., Ohshima S., Nakamura K., Kido Y., Sakamoto K., Kita K., Ohta N., Suzuki T
    • Journal Title

      J. Vet. Med. Sci.

      Volume: 73巻 Pages: 615-621

    • URL

      https://www.jstage.jst.go.jp/article/jvms/73/5/73_10-0481/_article

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590467
  • [Journal Article] TbUNC119 and its binding protein complex are essential for propagation, motility, and morphogenesis of Trypanosoma brucei procyclic form cells2010

    • Author(s)
      Ohshima S., Ohashi-Suzuki M., Miura Y., Yabu Y., Okada N., Ohta N., Suzuki T
    • Journal Title

      PLos ONE

      Volume: 5巻 Pages: 1-13

    • URL

      http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008729/?tool=pubmed

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590467
  • [Journal Article] Trypanosome alternative oxidase, a potential therapeutic target for sleeping sickness, is conserved among Trypanosoma brucei subspecies2010

    • Author(s)
      Nakamura K, Fujioka S, Fukumoto S, Inoue N, Sakamoto K, Hirata H, Kido Y, Yabu Y, Suzuki T, Watanabe Y, Saimoto H, Akiyama H, Kita K
    • Journal Title

      Parasitology International

      Volume: 59 Pages: 560-564

    • NAID

      10029826326

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590467
  • [Journal Article] Trypanosoma bruceivacuolar protein sorting 41 (VPS41) is required for intracellular iron utilization and maintenance of normal cellular morphology2007

    • Author(s)
      Lu, S., Suzuki, T., Iizuka, N., Ohshima, S., Yabu, Y., Suzuki, M., Wen, L., Ohta, N
    • Journal Title

      Parasitology 134

      Pages: 1639-1647

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390122
  • [Journal Article] Evaluation of the anthelmintic effects of artesunate against experimental Schistosoma mansoni infection in mice using different treatment protocols.2006

    • Author(s)
      Shaohong, Kumagai, Qinghua, Xiaolan, Ohmae, Yabu, Siwen et al.
    • Journal Title

      Parasitology International 55

      Pages: 63-68

    • NAID

      10017321629

    • Data Source
      KAKENHI-PROJECT-17390122
  • [Journal Article] Chemotherapeutic efficacy of ascofuranone in Trypanosoma vivax-infected mice without glycerol.2006

    • Author(s)
      Yabu, Suzuki, Nihei, Minagawa, Hosokawa, Nagai, Kita, Ohta
    • Journal Title

      Parasitology International 55

      Pages: 39-43

    • NAID

      10017321501

    • Data Source
      KAKENHI-PROJECT-17390122
  • [Journal Article] Chemotherapeutic efficacy of ascofuranone in Trypanosoma viax-infected mice without glycerol.2006

    • Author(s)
      Yabu Y.
    • Journal Title

      Parasitology International 55(1)

      Pages: 39-43

    • Data Source
      KAKENHI-PROJECT-17390122
  • [Journal Article] Mutational analysis of the Trypanosoma vivax alternative oxidase: The E(X)_6Y motif is conserved in both mitochondrial alternative oxidase and plastid terminal oxidase and is indispensable for enzyme activity.2005

    • Author(s)
      Nakamura, Sakamoto, Kido, Fujimoto, Suzuki, Suzuki, Yabu, Ohta, Tsuda, Onuma, Kita
    • Journal Title

      Biochemical and Biophysical Research Communications 334

      Pages: 593-600

    • Data Source
      KAKENHI-PROJECT-17390122
  • [Journal Article] Alternative oxidase (AOX) genes of African trypanosomes: Phylogeny and evolution of AOX and plastid terminal oxidase families.2005

    • Author(s)
      Suzuki, Hashimoto, Yabu, Majiwa, Ohshima, Suzuki, Lu, Hato, Kido, Sakamoto, Nakamura, Kita, Ohta
    • Journal Title

      Journal of Eukaryotic Microbiology 52

      Pages: 374-381

    • Data Source
      KAKENHI-PROJECT-17390122
  • [Journal Article] Protective effect of vaccination with Toxoplasma lysate antigen and CpG as an adjuvant against Toxoplasma gondii in susceptible C57BL/6 mice.2005

    • Author(s)
      El-Kalky, Shaohong, Kumagai, Yabu, Noureldin, Saudy et al.
    • Journal Title

      Microbiology and Immunology 49

      Pages: 639-646

    • NAID

      10016567868

    • Data Source
      KAKENHI-PROJECT-17390122
  • [Presentation] アフリカトリパノソーマ原虫の動き関連分子、TbUNC119の解析2011

    • Author(s)
      鈴木高史、大島茂、鈴木光子、籔義貞、太田伸生
    • Organizer
      第80回日本寄生虫学会総会
    • Place of Presentation
      東京慈恵会医科大学本館(東京都)
    • Year and Date
      2011-07-18
    • Data Source
      KAKENHI-PROJECT-21590467
  • [Presentation] Cryptoaporidium parvumシアン耐性酸化酵素(Alternative oxidase, AOX)の酵素学的解析2011

    • Author(s)
      原田倫世、藤本陽子、松崎素道、城戸康年、坂元君年、籔義貞、中井裕、北潔
    • Organizer
      第80回日本寄生虫学会総会
    • Place of Presentation
      東京慈恵会医科大学本館(東京都)
    • Year and Date
      2011-07-18
    • Data Source
      KAKENHI-PROJECT-21590467
  • [Presentation] Trichomonas foetusの市販培養液を用いた培養法の開発2010

    • Author(s)
      籔義貞、真田祥太郎、岡田則子
    • Organizer
      日本寄生虫学会西日本支部大会
    • Place of Presentation
      岡山大学
    • Year and Date
      2010-11-06
    • Data Source
      KAKENHI-PROJECT-21590467
  • [Presentation] 「ミトコンドリア」を持たない寄生原虫・クリプトスポリジウムにおける呼吸鎖の生化学的解析2009

    • Author(s)
      原田倫世, 藤本陽子, 城戸康年, 坂元君年, 松崎素道, 籔義貞, 鈴木高史, 笹原武史, 中井裕, 北潔
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2009-10-22
    • Data Source
      KAKENHI-PROJECT-21590467
  • [Presentation] Target of glycerol in ascofuranone/glycerol in vitro trypanocidal effect to African trvoanosomes2007

    • Author(s)
      Fujioka, S., Nakamura, K., Kido, Y., Sakamoto, K., Haga, Y., Saimoto, H., Suzuki, T., Yabu, Y., Kita, K
    • Organizer
      80th annual meeting of Biochemistry
    • Place of Presentation
      Japan
    • Year and Date
      2007-12-14
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390122
  • 1.  SAIMOTO Hiroyuki (20186977)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 2.  OGIHARA Yukio (70080166)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  NOSE Mitsuhiko (60228327)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  INOUE Makoto (50191888)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  TAKEDA Tadahiro (90106253)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  KITA Kiyoshi (90134444)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 7.  SUZUKI Takashi (70305530)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 8.  HIRUMI Hiroyuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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