OMORI Hitoshi 大森齊

… Alternative Names

OHMORI Hitoshi 大森齊

大森齊オオモリヒトシ

大森齋オオモリヒトシ

大森斉オオモリヒトシ

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Researcher Number	70116440
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2012 – 2014: 岡山大学, 自然科学研究科, 教授 2009 – 2011: Okayama University, 大学院・自然科学研究科, 教授 2006: Okayama University, Biotechnology, Professor, 大学院自然科学研究科, 教授 2005 – 2006: 岡山大学, 大学院・自然科学研究科, 教授 2004: 岡山大学, 工学部, 教授 … More 1998 – 2002: 岡山大学, 工学部, 教授 1992 – 1996: 岡山大学, 工学部, 教授 1987 – 1989: 岡山大学, 工学部, 教授 Less
Review Section/Research Field	Principal Investigator 生物・生体工学 / Biofunction/Bioprocess / Biological Sciences / 発酵工学 / 免疫の制御機構 Except Principal Investigator Biological pharmacy
Keywords	Principal Investigator 胚中心 / RAG遺伝子 / 抗体 / V(D)J再構成 / 親和性成熟 / 成熟B細胞 / インターロイキン7 / アレルギー / 体細胞変異 / トランスジェニックマウス … More / 遺伝子ノックアウトマウス / ES細胞 / 遺伝子ターゲッティング / 肥満細胞 / 遺伝子再構成 / モノクローナル抗体 / リンパ球 / 突然変異 / 濾胞樹状細胞 / B細胞 / IgE抗体 / RAG genes / V(D)J recombination / transgenic mouse / germinal center / 免疫複合体 / Fcγレセプター / 炎症 / クローン選択 / 抗原レセプター / V(D)J再編成 / アポトーシス / 生体防御 / 抗体医薬 / 体細胞高頻度突然変異 / IL-21 / AID / B細胞株 / 単球系細胞分化 / CSF-1受容体 / IL-34 / CSF-1 / 細胞情報伝達 / 胚中心B細胞 / マイクロRNA / 胚中心B 細胞 / 単球系細胞 / 胚中心Ｂ細胞 / ＣＳＦ－１受容体 / シグナル伝達 / RNAi / Ｂ細胞 / 骨髄系細胞 / 動物細胞 / 遺伝子導入 / 熱ショック / 5-アザシチジン / 一過性遺伝子発現 / 安定形質転換 / β-ガラクトシダーゼ / プラスミド / 動物細胞株 / 安定発現 / mRNA / ノーザンブロット / タンパク合成 / mammalian cells / gene transfer / stable transfectant / 5-azacytidine / 2-aminopurine / beta-galactosidase / gene expression / recombinant product / 遺伝子ターゲティング / Fcガンマ受容体 / アナフィラキ- / IgG免疫複合体 / Fcガンマレセプター / 遺伝子ノックアウト / 変異マウス / IgG Fc受容体 / クラススイッチ / ノックアウトマウス / gene targeting / Fc gamma receptor / gene-knockout mouse / allergy / anaphylaxy / IgG immune complex / B cells / mast cells / ハイブリドーマ / 遺伝子組み換え / Allergy / IgE antibody / hybridoma / monoclonal antibody / nematode / IL-7レセプター / mature B cells / IL-7 receptor / transgenic mice / 抗体遺伝子 / Bリンパ球 / 遺伝子再編成 / IL-7 / V(D)J再構 / Antibody / antibody genes / affinity maturation / somatic mutation / B lymphocytes / gene rearrangement / ニワトリ / 感染防御 / タンパク工学 / リンパ組織 / 分子進化工学 / 体細胞突然変異 / 遺伝子発現制御 / タンパク質工学 / antibody / B cell / somatic hypermutation / chicken / protection of infection / protein engineering / lymphoid tissue / molecular evolution technology / マウスリンパ球 / 初代培養 / 抗体産生 / 無清血培地 / T細胞 / β-シクロデキストリン / 無血清培地 / リンパ球の無血清培養 / 抗体応答 / Murine lymphocytes / Primary culture / Antibody response / Serum-free medium / T cells / beta-Cyclodextrin … More Except Principal Investigator SHR / IRA分画 / 免疫抑制性蛋白 / IRAの欠損 / SHR血漿欠損蛋白 / 免疫抑制蛋白 / 抗免疫抑制蛋白モノクローン抗体 / ConA応答 Less

Identification of a new type of monocytic cell that promotes affinity maturation and characterization of its B cell-activation mechanismPrincipal Investigator
- Principal Investigator
  
  OHMORI HITOSHI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Okayama University
Analysis of affinity maturation process of antibodies using a novel FDC line and its application.Principal Investigator
- Principal Investigator
  
  OMORI Hitoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Okayama University
Molecular evolution system of proteins using a B cell line with spontaneous mutation machineryPrincipal Investigator
- Principal Investigator
  
  OHMORI Hitoshi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  OKYAMA UNIVERSITY
末梢B細胞におけるV(D)J遺伝子再構成の高親和性抗体レパトア形成への寄与Principal Investigator
- Principal Investigator
  
  大森斉
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Okayama University
胚中心で発現するRAG遺伝子産物のB細胞レパトアの多様化と選択への関与Principal Investigator
- Principal Investigator
  
  大森斉
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Okayama University
Analysis and application of the capability of immune system to improve antigen-specificity of antibodies.Principal Investigator
- Principal Investigator
  
  OHMORI Hitoshi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  生物・生体工学
- Research Institution
  Okayama University
胚中心B細胞に再発現するRAG遺伝子産物によるV(D)J再構成とその意義の解明Principal Investigator
- Principal Investigator
  
  大森齊
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Okayama University
胚中心B細胞に再発現するRAG遺伝子産物によるV(D)J再構成とその意義の解明Principal Investigator
- Principal Investigator
  
  大森斉
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Okayama University
Suppression of allergy with non-specific monoclonal IgE antibodies.Principal Investigator
- Principal Investigator
  
  OHMORI Hitoshi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  生物・生体工学
- Research Institution
  OKAYAMA UNIVERSITY
Analysis of V(D)J recombination by RAGs expressed in mature B cells.Principal Investigator
- Principal Investigator
  
  OHMORI Hitoshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  免疫の制御機構
- Research Institution
  OKAYAMA UNIVERSITY
遺伝子ノックアウトを応用したアレルギー発症モデルの確立Principal Investigator
- Principal Investigator
  
  大森斉
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  生物・生体工学
- Research Institution
  Okayama University
Studies on the development of allergy treatment using gene-knockout mice.Principal Investigator
- Principal Investigator
  
  OHMORI Hitoshi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  生物・生体工学
- Research Institution
  Okayama University
Establishment of procedures to enhance the expression of introduced genes in mammalian cells.Principal Investigator
- Principal Investigator
  
  OHMORI Hitoshi
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  発酵工学
- Research Institution
  Okayama University
Development of a serum-free medium for lymphocyte cultures.Principal Investigator
- Principal Investigator
  
  OHMORI Hitoshi
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  発酵工学
- Research Institution
  Okayama University
自然発症高血圧ラット(SHR)の免疫抑制性α-グロブリン蛋白の欠損に関する研究
- Principal Investigator
  
  山本格
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University

All 2015 2014 2013 2012 2011 2010 2009 2006 2005 2004 Other

All Journal Article Presentation Book Patent

[Book] 改訂細胞工学2010
- Author(s)
  永井和夫、大森斉、金山直樹、町田千代子
- Total Pages
  230
- Publisher
  講談社
- Data Source
  KAKENHI-PROJECT-21360405
[Book] 改訂細胞工学2010
- Author(s)
  永井和男、大森齊、町田千代子、金山直樹
- Total Pages
  230
- Publisher
  講談社サイエンティフィック
- Data Source
  KAKENHI-PROJECT-21360405
[Journal Article] MicroRNA-100-5p indirectly modulates the expression of Il6, Ptgs1/2 and Tlr4 mRNA in the mouse follicular dendritic cell-like cell line, FL-Y.2015
- Author(s)
  Aungier, S.R., Ohmori, H., Clinton, M., Mabbott, N.A.
- Journal Title
  
  Immunology
  
  Volume: 144 Pages: 34-35
- DOI
  10.1111/imm.12342
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24560961
[Journal Article] CSF-1 receptor-mediated differentiation of a new type of monocytic cell with B cell-stimulating activity: its selective dependence on IL-342014
- Author(s)
  Fumihiro Yamane
- Journal Title
  
  Journal of Leukocyte Biology
  
  Volume: 95 Pages: 19-31
- DOI
  10.1189/jlb.0613311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24360343, KAKENHI-PROJECT-24560961, KAKENHI-PROJECT-25460590
[Journal Article] Activa-tion-induced cytidine deaminase(AID)-dependent somatic hypermutation requires a splice isoform of the serine/arginine-rich(SR) protein SRSF12012
- Author(s)
  Kanehiro, Y., Ohmori, H. Kanayama, N., et al.(10名中9番目)
- Journal Title
  
  Proceeding of the National Academy of Sciences, USA.
  
  Volume: 109 Pages: 1216-1271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360405
[Journal Article] Activation-induced cytidine deaminase (AID)-dependent somatic hypermuation requires splice isoform of the serine/arginine-rich (SR) protein SRSF12012
- Author(s)
  Kanehiro, Y., Ohmori, H.Kanayama, N., at al
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 109 Pages: 1216-1221
- DOI
  10.1073/pnas.1120368109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360405, KAKENHI-PROJECT-23657092, KAKENHI-PROJECT-23790537
[Journal Article] 抗体遺伝子への突然変異機能を有するニワトリＢ細胞株の機能拡張によるin vitroモノクローナル抗体作製・改良システム2012
- Author(s)
  金山直樹、大森　齊
- Journal Title
  
  細胞工学
  
  Volume: 31 Pages: 1159-1165
- Data Source
  KAKENHI-PROJECT-24560961
[Journal Article] 胚中心におけるＢ細胞のnegative selectionと濾胞樹状細胞2012
- Author(s)
  曲　正樹、金山直樹、大森　齊
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 58 Pages: 259-265
- Data Source
  KAKENHI-PROJECT-24560961
[Journal Article] IL-21-dependent B cell death driven by prostaglandin E2, a product secreted from follicular dendritic cells2011
- Author(s)
  Magari, M. Ohmori, H., et al.(7名中7番目)
- Journal Title
  
  Journal of Immunology
  
  Volume: 187 Pages: 4210-4218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360405
[Journal Article] Expression of mesenchyme-specific gene signatures by follicular dendritic cells : insights from the meta-analysis of microarray data from multiple mouse cell populations2011
- Author(s)
  Mabbott, N., Ohmori, H., et al
- Journal Title
  
  Immunology
  
  Volume: 133 Pages: 482-498
- DOI
  10.1111/j.1365-2567.2011.03461.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360405
[Journal Article] IL-21-dependent B cell death driven by prostaglandin E2, a product secreted from follicular dendritic cells2011
- Author(s)
  Magari, M.Ohmori, H., et al
- Journal Title
  
  J. Immunol
  
  Volume: 187 Pages: 4210-4218
- DOI
  10.4049/jimmunol.1100934
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360405, KAKENHI-PROJECT-22790931, KAKENHI-PROJECT-23790537
[Journal Article] Expression of mesen-chyme-specific gene signatures by follicular dendritic cells : insights from the meta-analysis of microarray data frommultiple mouse cell popu-lations2011
- Author(s)
  Mabbott, N., Ohmori, H., et al.(8名中6番目)
- Journal Title
  
  Immunology
  
  Volume: 133 Pages: 482-498
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360405
[Journal Article] Enhancement of hypermutation frequency in the chicken B cell line DT40 for efficient diversification of antibody repertoire.2010
- Author(s)
  Magari, M., Kanehiro, Y., Todo, K., Ikeda, M., Kanayama, N., Ohmori, H.
- Journal Title
  
  Biochem.Biphys.Res.Commmun.
  
  Volume: 396 Pages: 353-358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360405
[Journal Article] Efficient affinity maturation of antibodies in an engineered chicken B cell line DT40-SW by increasing point mutation2010
- Author(s)
  Kajita, M., Okazawa, T., Ikeda, M., Todo, K., Magari, M., Kanayama, N., Ohmori, H.
- Journal Title
  
  J.Biosci.Bioeng.
  
  Volume: 351 Pages: 351-358
- NAID
  110007730029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360405
[Journal Article] Conditional transformation of immunoglobulin mutation pattern from gene conversion to point mutation by controlling XRCC3 expression in the DT40 B cell line.2010
- Author(s)
  Kajita, M., Hagari, M., Todo, K., Kanayama, N., Ohmori, H.
- Journal Title
  
  Journal of Bioscience and Bioengoneering 109
  
  Pages: 407-410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360405
[Journal Article] Efficient affinity maturation of antibodies in an engineered chicken B cell line DT40-SW by increasing point mutation.2010
- Author(s)
  Kajita, M., Kanayama, N. Ohmori, H., et al.(7名中7番目)
- Journal Title
  
  J. Biosci. Bioeng.
  
  Volume: 351 Pages: 351-358
- NAID
  110007730029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360405
[Journal Article] Enhance-ment of hypermutation frequency in the chicken B cell line DT40 for Efficient diversification of antibody repertoire.2010
- Author(s)
  Magari, M., Kanehiro, Y., Ohmori, H., et al.(6名中6番目)
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 396 Pages: 353-358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360405
[Journal Article] Enhancement of antibody production from a chicken B cell line DT40 by reducing Pax5 expression.2009
- Author(s)
  Magari, M., Aya, T., Ikeda, M., Todo, K.Kanayam, N., Ohmori, H.
- Journal Title
  
  Journal of Bioscience and Bieengineering 107
  
  Pages: 206-209
- NAID
  110007110260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360405
[Journal Article] Establishment of lymphotoxin beta receptor signaling-dependent cell lines with follicular dendritic cell phenotypes from mouse lymph nodes.2006
- Author(s)
  Nishikawa Y, Hikida M, Magari M, Kanayama N, Mori M, Kitamura H, Kurosaki T, Ohmori H.
- Journal Title
  
  J.Immunol. Vol.177(8)
  
  Pages: 5204-5214
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16360414
[Journal Article] Novel in vitro screening system for monoclonal antibodies using hypermutating chicken B cell library.2006
- Author(s)
  Todo K, Miyake K, Magari M, Kanayama N, Ohmori H.
- Journal Title
  
  J. Biosci. Bioeng. 102・5
  
  Pages: 478-481
- NAID
  110006148703
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16360414
[Journal Article] Genetic manipulation of an exogenous non-immunoglobulin protein by gene conversion machinery in a chicken B cell line2006
- Author(s)
  Hitoshi Ohmori
- Journal Title
  
  Nucleic Acids Research 34・2
- Data Source
  KAKENHI-PROJECT-16360414
[Journal Article] A system for generation of antibodies and mutant proteins using a B cell line with an ON/OFF control device for hypermutation machinery. (Japanese)2006
- Author(s)
  Ohmori H., Todo K., Kanayama N.
- Journal Title
  
  Experimental Medicine Vol.24 (9)
  
  Pages: 1331-1335
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16360414
[Journal Article] 変異機能のON/OFF制御可能なB細胞株を用いた抗体および変異タンパク質の作製システム2006
- Author(s)
  大森齊, 藤堂景史, 金山直樹
- Journal Title
  
  実験医学 24(9)
  
  Pages: 1331-1335
- Data Source
  KAKENHI-PROJECT-16360414
[Journal Article] 変異機能のON/OFF制御可能なB細胞株を用いた抗体および変異タンパク質の作製システム2006
- Author(s)
  大森齊, 藤堂景史, 金山直樹
- Journal Title
  
  実験医学 24・6
  
  Pages: 1331-1335
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16360414
[Journal Article] Establishment of lymphotoxin beta receptor signaling-dependent cell lines with follicular dendritic cell phenotypes from mouse lymph nodes.2006
- Author(s)
  Nishikawa Y, Hikida M, Magari M, Kanayama N, Mori M, Kitamura H, Kurosaki T, Ohmori H.
- Journal Title
  
  J. Immunol. 177・8
  
  Pages: 5204-5214
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16360414
[Journal Article] Genetic manipulation of an exogenous non-immunoglobulin protein by gene conversion machinery in a chicken B cell line.2006
- Author(s)
  Kanayama N, Todo K, Takahashi S, Magari M, Ohmori H.
- Journal Title
  
  Nucleic Acids Res. 34・2
  
  Pages: 1-9
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16360414
[Journal Article] Establishment of lymphotoxin b receptor signaling-dependent cell lines with follicular dendritic cell phenotyps from mouse lymph nodes2006
- Author(s)
  Hitoshi Ohmori 他
- Journal Title
  
  Journal of Immunoloyg 177(8)
  
  Pages: 5204-5214
- Data Source
  KAKENHI-PROJECT-16360414
[Journal Article] Novel in vitro screening system for monoclonal antibodies using hypermutating chicken B cell library.2006
- Author(s)
  Todo K, Miyake K, Magari M, Kanayama N, Ohmori H.
- Journal Title
  
  J.Biosci.Bioeng. Vol.102(5)
  
  Pages: 478-481
- NAID
  110006148703
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16360414
[Journal Article] Novel in vitro screening system for monoclonal antibodies using hypermutating chicken B cell library2006
- Author(s)
  Hitoshi Ohmori 他4名
- Journal Title
  
  Journal of Bioscience and Bioengineering 102(5)
  
  Pages: 478-481
- NAID
  110006148703
- Data Source
  KAKENHI-PROJECT-16360414
[Journal Article] Genetic manipulation of an exogenous non-immunoglobulin protein by gene conversion machinery in a chicken B cell line.2006
- Author(s)
  Kanayama N, Todo K, Takahashi S, Magari M, Ohmori H.
- Journal Title
  
  Nucleic Acids Res. 34 (2)
  
  Pages: 1-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16360414
[Journal Article] Reversible switching of immunoglobulin hypermutation machinery in a chicken B cell line2005
- Author(s)
  Hitoshi Ohmori
- Journal Title
  
  Biochemical and Biophysical Research Communications 327
  
  Pages: 70-75
- Data Source
  KAKENHI-PROJECT-16360414
[Journal Article] Reversible switching of immunoglobulin hypermutation machinery in a chicken B cell line.2005
- Author(s)
  Kanayama N., Todo K., Reth M., Ohmori H.
- Journal Title
  
  Biochem.Biophys.Res.Commn. Vol.327 (1)
  
  Pages: 70-75
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16360414
[Journal Article] Analysis of marginal zone B cell development in the mouse with limited B cell diversity : role of the antigen receptor signals in the recruitment of B cells to the marginal zone.2005
- Author(s)
  Kanayama, N., Cascalho, M., Ohmori.H.
- Journal Title
  
  J. Immunol. 174・2
  
  Pages: 1438-1445
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16360414
[Journal Article] Reversible switching of immunoglobulin hypermutation machinery in a chicken B cell line.2005
- Author(s)
  Kanayama, N., Todo, K., Reth, M., Ohmori, H.
- Journal Title
  
  Biochem. Biophys. Res. Commn. 327・1
  
  Pages: 70-75
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16360414
[Journal Article] Analysis of marginal zone B cell development in the mouse with limited B cell diversity : role of the antigen receptor signals in the recruitment of B cells to the marginal zone.2005
- Author(s)
  Kanayama N., Cascalho M., Ohmori H.
- Journal Title
  
  J.Immunol. 174(2)
  
  Pages: 1438-1445
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16360414
[Journal Article] Analysis of Marginal Zone B Cell Development in the Mouse with Limited B Cell Diversity : Role of the Antigen Receptor Signals in the Recruitment of B Cells to the Marginal Zone2005
- Author(s)
  Hitoshi Ohmori
- Journal Title
  
  The Journal of Immunology 174
  
  Pages: 1438-1445
- Data Source
  KAKENHI-PROJECT-16360414
[Patent] 細胞の遺伝子変異機能の制御による変異タンパク質の作製方法2011
- Inventor(s)
  金山直樹、大森斉
- Industrial Property Rights Holder
  岡山大学
- Acquisition Date
  2011-04-09
- Data Source
  KAKENHI-PROJECT-21360405
[Patent] 細胞の遺伝子変異機能の制御による変異タンパク質の作製方法2010
- Inventor(s)
  大森齊、金山直樹
- Industrial Property Rights Holder
  岡山大学
- Acquisition Date
  2010-04-09
- Data Source
  KAKENHI-PROJECT-21360405
[Patent] ヒト型抗体を産出するB細胞の作製方法2010
- Inventor(s)
  金山直樹、大森齊
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Number
  2010-258404
- Filing Date
  2010-11-18
- Data Source
  KAKENHI-PROJECT-21360405
[Patent] ヒト型抗体を産出するB細胞の作製方法2010
- Inventor(s)
  金山直樹、大森斉
- Industrial Property Rights Holder
  岡山大学
- Filing Date
  2010-11-18
- Data Source
  KAKENHI-PROJECT-21360405
[Patent] 細胞の遺伝子変異機能の制御による変異タンパク質の作製方法2004
- Inventor(s)
  大森齊, 金山直樹
- Industrial Property Rights Holder
  岡山大学
- Patent Publication Number
  2006-109711
- Filing Date
  2004-10-12
- Acquisition Date
  2006-04-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16360414
[Presentation] Follicular dendritic cells induce a new class of myeloid cells with unique B cell stimulating activities: specific dependence on IL-34/CSF-1R signaling pathway.2013
- Author(s)
  Yamane, F., Nishikawa, Y., Matsui, K., Asakura, M., Iwasaki, E., Watanabe, K., Tanimoto, H., Sano, H., Fujiwara, Y., Stanley, E. R., Kanayama, N., Mabbott, N. A., Magari, M., Ohmori, H.
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  ミラノ（イタリア）
- Data Source
  KAKENHI-PROJECT-24560961
[Presentation] IL-34-dependent monocytic cells that promote centroblast-associated phenotype expression in mouse activated B cells2012
- Author(s)
  曲　正樹、大森　齊他９名
- Organizer
  日本免疫学会総会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-24560961
[Presentation] IL-34依存性の新規単球系細胞の機構解析2011
- Author(s)
  松井一恵、大森齊, 他5名
- Organizer
  日本免疫学会大会
- Place of Presentation
  幕張メッセ(千葉県)
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-21360405
[Presentation] DT40を用いるin vitro抗体作製・改良システムの開発2011
- Author(s)
  金山直樹、曲正樹、大森齊
- Organizer
  日本分子生物学会大会
- Place of Presentation
  パシフィコ横浜(神奈川県)(招待講演)
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-21360405
[Presentation] 変異導入能力を有する培養B細胞株を用いたin vitro抗体作製システムの高機能化2010
- Author(s)
  金山直樹、曲正樹、梶田真道、金広優一、藤堂景史、大森齊
- Organizer
  第31回日本分子生物学会年会、第81回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21360405
[Presentation] 抗体の親和性成熟機構の解析とそれに基づく効率的in vitro抗体作製システムの開発2009
- Author(s)
  大森齊
- Organizer
  蛋白質と酵素の構造と機能に関する九州シンポジウム
- Place of Presentation
  唐津シーサイドホテル(佐賀県)
- Year and Date
  2009-09-11
- Data Source
  KAKENHI-PROJECT-21360405
[Presentation] DT40-SWを用いるin vitro抗体作製システムの高機能化 : 変異様式の転換による高性能抗体作製2009
- Author(s)
  梶田真道、曲正樹、藤堂景史、金山直樹、大森齊
- Organizer
  日本生物工学会大会
- Place of Presentation
  名古屋大学(愛知県)
- Year and Date
  2009-09-24
- Data Source
  KAKENHI-PROJECT-21360405
[Presentation] 変異能力を有するニワトリB細胞株を用いた抗体の親和性成熟 : DT40-SWを用いたマウスモノクローナル抗体の改変2009
- Author(s)
  金山直樹、小島聡史、藤井忍、北村幸一、井上和恵、岡山展久、松田修一、藤堂景史、曲正樹、大森齊
- Organizer
  日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21360405
[Presentation] 変異能力を有するニワトリB細胞株を用いた抗体の親和性成熟 : 外来の抗体可変部遺伝子のDT40-SWにおける発現・改良系の構築2009
- Author(s)
  小島聡史、藤井忍、北村幸一、井上和恵、岡山展久、松田修一、藤堂景史、曲正樹、金山直樹、大森齊
- Organizer
  日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21360405
[Presentation] FDCとIL-21の関与する胚中心B細胞の新規な負の選択機構2009
- Author(s)
  藤井康正、西川裕美子、西尾裕美、金山直樹、大森齊
- Organizer
  日本免疫学会総会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-21360405
[Presentation] 抗体の親和性成熟機構の解析とそれに基づく効率的in vitro抗体作製システムの開発2009
- Author(s)
  大森斉
- Organizer
  蛋白質と酵素の構造と機能に関する九州シンポジウム
- Place of Presentation
  唐津シーサイドホテル(佐賀)
- Year and Date
  2009-09-11
- Data Source
  KAKENHI-PROJECT-21360405
[Presentation] DT40-SWを用いるin vitro抗体作製システムの高機能化 : 遺伝子変換と点突然変異の転換システムの構築2009
- Author(s)
  曲正樹、梶田真道、金山直樹、大森齊
- Organizer
  日本生物工学会大会
- Place of Presentation
  名古屋大学(愛知県)
- Year and Date
  2009-09-24
- Data Source
  KAKENHI-PROJECT-21360405
[Presentation] IL-34依存的に発生する新規単球系細胞の分化機構；濾胞樹状細胞によるIL-34特異的作用の解析
- Author(s)
  小川紗也香，大森斉，曲正樹　他６名
- Organizer
  第３７回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-12-01 – 2014-12-04
- Data Source
  KAKENHI-PROJECT-24560961

1. MAGARI Masaki (50359882)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
2. HIKIDA Masaki (60228715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. KANAYAMA Naoki (70304334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 山本格 (20028848)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KOMORIYA Keiji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OMORI Hitoshi 大森 齊

OHMORI Hitoshi 大森 齊

大森 齊 オオモリ ヒトシ

大森 齋 オオモリ ヒトシ

大森 斉 オオモリ ヒトシ

Research Projects

Research Products

Co-Researchers

Identification of a new type of monocytic cell that promotes affinity maturation and characterization of its B cell-activation mechanismPrincipal Investigator

Principal Investigator

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Research Institution

Analysis of affinity maturation process of antibodies using a novel FDC line and its application.Principal Investigator

Principal Investigator

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Research Institution

Molecular evolution system of proteins using a B cell line with spontaneous mutation machineryPrincipal Investigator

Principal Investigator

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Research Institution

末梢B細胞におけるV(D)J遺伝子再構成の高親和性抗体レパトア形成への寄与Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

胚中心で発現するRAG遺伝子産物のB細胞レパトアの多様化と選択への関与Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Analysis and application of the capability of immune system to improve antigen-specificity of antibodies.Principal Investigator

Principal Investigator

Project Period (FY)

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胚中心B細胞に再発現するRAG遺伝子産物によるV(D)J再構成とその意義の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

胚中心B細胞に再発現するRAG遺伝子産物によるV(D)J再構成とその意義の解明Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Suppression of allergy with non-specific monoclonal IgE antibodies.Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Analysis of V(D)J recombination by RAGs expressed in mature B cells.Principal Investigator

Principal Investigator

Project Period (FY)

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遺伝子ノックアウトを応用したアレルギー発症モデルの確立Principal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Studies on the development of allergy treatment using gene-knockout mice.Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Establishment of procedures to enhance the expression of introduced genes in mammalian cells.Principal Investigator

Principal Investigator

OMORI Hitoshi 大森齊

OHMORI Hitoshi 大森齊

大森齊オオモリヒトシ

大森齋オオモリヒトシ

大森斉オオモリヒトシ

[Book] 改訂細胞工学2010