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KUBO Hirotaka  久保 宏隆

ORCIDConnect your ORCID iD *help
Researcher Number 70119791
External Links
Affiliation (based on the past Project Information) *help 2008: 聖徳大学, 人文学部, 教授
2002: 東京慈恵会医科大学, 医学部, 助講師
1999 – 2001: 東京慈恵会医科大学, 医学部, 助教授
1999 – 2000: 東京慈恵会医科大学, 外科学第2教室, 助教授
1992 – 1994: Jikei University school of Medicine, 医学部, 講師 … More
1993: Jikei Med.Univ.Ch.Resi, 第二外科教室, 講師
1992: 東京慈恵会医科大学医学部, 第2外科, 講師
1991: 東京慈恵会医科大学, 医学部, 助手
1988 – 1991: 東京慈恵会医科大学, 第2外科教室, 講師
1989: Lecturer, The Second Department of Surgery, The Jikei University School of Medicine., 第二外科, 講師
1988: 東京慈恵会医科大学, 医学部第2外科, 講師
1987: 東京慈恵会医科大学, 医学部・第二外科, 講師
1987: 東京慈恵会医科大学, 第二外科教室, 講師 Less
Review Section/Research Field
Principal Investigator
Digestive surgery / General surgery
Except Principal Investigator
Digestive surgery / Eating habits, studies on eating habits / General surgery
Keywords
Principal Investigator
プリン代謝 / ストレス潰瘍 / 尿酸 / フリ-ラジカル / フリーラジカル / キサンチンオキシダーゼ / ヒポキサンチン / キサンチン / アロプリノール / 胃粘膜防御因子 … More / 組織内ヒポキサンチン / 組織内キサンチン / 胃粘膜微小循環 / 胃粘膜防御因子・ラジカル / 組織内尿酸値 / キサンチン・オキシ-ゼ / キサンチン・オキシ-ゼ抑制剤 / ラジカル阻止剤 / stress ulcer / radical / purine metabolism / xanthine oxidase / hypoxanthine / xanthine / uric acid / 肝細胞癌(hepatocellular carcinoma) / グルタミン代謝(glutamine metabolism) / ミトコンドリ酸化的リン酸化能(mitochondrial oxydative phosphorylation) / amidophosphoribosytransferase活性 / Hypoxanthine / Xanthine / 尿酸(uric acid) / グルタミン / 肝細胞癌 / グルタミン代謝 / グルタミン酸 / グルタミン合成酵素 / グルタミン分解酵素 / ミトコンドリア酸化的リン酸化 / DAB肝癌 / 乳癌ホルモン療法 / 乳癌細胞 / アポトーシス / 抗エストロゲン薬 / 感受性試験 / ミトコンドリア呼吸系酵素 / エストロゲン / 乳癌ホルモン治療 / 抗エストロゲン / エストゴゲン受容体 / Breast cancer / Hormon therapy / Estrogen / Apotpsis / Antiestorogen / Tamoxifen / DNA damege / Mitochondrial respiration / Caspase-3 / 高カロリ-輸液 / 胃粘膜ムコ物質 / ヘキソサミン / 胃粘膜増殖細胞帯 / 胃粘膜ー粘液関門 / 粘膜下血流 / 1.高カロリー輸液 / 2.ストレス潰瘍 / 3.胃粘膜ムコ物質 / 4.ヘキソサミン / 5.胃粘膜増殖細胞帯 / 6.胃粘膜ー粘液関門 / STRESS ULCER / TPN ADMINISTRATION / GASTRIC MUCOSAL MUCOIDS / HEXIOSAMINE / PURUIC METABOLISM / URIC ACID / GENERATIVE CELL ZONE IN GASTRIC MUMOSA / DEFENSIVE MUCAS-MUCOSAL BARRIER … More
Except Principal Investigator
プリン代謝 / LH-RH analogue / Tamoxifen / 急性の膵炎 / フリ-ラジカル / キサンチンオキシダ-ゼ / 組織内尿酸 / 脂肪酸 / アディポネクチン / 培養細胞 / PCR / トランス脂肪酸 / PPAR / 小腸粘膜 / 活性酸素 / 虚血 / ギサンチンオキシターゼ / キサンチンオキシターゼ / 小腸移植 / 粘膜障害 / intestinal mucosa / free radical / ischemia / purine metabolism / xanthine oxidase / 骨粗鬆症 / LH-RHagonist / 閉経 / 骨障害 / Tamaxifen / Osteoporosis / 肝不全 / 経腸栄養 / 遺伝子治療 / アデノウイルス / アラツウイルス / Liver Failure / Enteral Nutrution / Gene Therapy / Adenovirus / ストレス潰瘍 / potentia1 defference / 胃粘膜血流 / 防御因子 / 攻撃因子 / 水浸拘束ストレス潰瘍モデル / 閉塞性黄疽モデル / Potentia1 Difference(PD) / ガストリンレセプタ-アンタゴニスト / H_2ーレセプタ-アンタゴニスト / 水浸拘束ストレスモデル / 閉塞性黄疸モデル / PD pH粘液 / 胃粘膜ヒスタミン / PO / pH / 粘液 / STRESS ULCER / JAUNDICE ULCER / AGGRESIVE FACTOR / DEFENSIVE FACTOR Less
  • Research Projects

    (10 results)
  • Co-Researchers

    (17 People)
  •  Analysis of induction mechanism of hypoadiponectinemia by trans-fatty acids.

    • Principal Investigator
      KNOU Kazutaka
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Eating habits, studies on eating habits
    • Research Institution
      Seitoku University
  •  The Trial of Gene Therapy Using an Enteral Nutrition for the Treatment of Liver.

    • Principal Investigator
      OKAMOTO Tomoyoshi
    • Project Period (FY)
      2000 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      JIKEI UNIVERSITY SCHOOL OF MEDICINE
  •  Establishment of a short term selection methodes of anti-estogenic drugs fitted for individual breast cancer case using apoptosis as a marker.Principal Investigator

    • Principal Investigator
      KUBO Hirotaka
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Jikei University school Medicine
  •  THE EFFECT OF LH-RH ANALOGUE OR/AND TAMOXIFEN ON BONE IN RATS

    • Principal Investigator
      SUZUKI Yutaka
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      JIKEI UNIVERSITY SCHOOL OF MEDICINE
  •  肝細胞癌におけるエネルギー代謝(グルタミン、プリン代謝より)特性における実験的研究Principal Investigator

    • Principal Investigator
      久保 宏隆
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Jikei University School of Medicine
  •  Experiments in the effect of ischemic-reperfusion injury and regeneration of the mucosa in small bowel transplantation

    • Principal Investigator
      KASIWAZAKI Osamu
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Jikei Medical Univ.
  •  急性膵炎発生メカニズムにおけるプリン代謝面からの実験的検討(特にキサンチンオキシダ-ゼ活性の関与について)

    • Principal Investigator
      YOSHII Shuji
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Jikei University School of Medicine
  •  RELATIONSHIP BETWEEN STRESS ULCER FORMATION AND RADIKAL(Study from Purine Metabolism)Principal Investigator

    • Principal Investigator
      KUBO Hirotaka
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Jikei University school of Medicine
  •  Causing mechanism and treatment for stress ulcer

    • Principal Investigator
      IKEUCHI Junji
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Jikei University School of Medicine
  •  EXPERIMENTAL STUDY ON EFFECTS OF TPN FOR PREVENTION OF STRESS ULCER OCCURRENCEPrincipal Investigator

    • Principal Investigator
      KUBO Hirotaka
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Jikei University School of Medicine
  • 1.  YOSHII Shuji (50200928)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  HORI Noriya (20199524)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  TABATA Yasuhiro (20256415)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  KNOU Kazutaka (70111507)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  TUDA Naoya (50246419)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  KASIWAZAKI Osamu (20056518)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  SUZUKI Yutaka (20241060)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  田部井 功 (50266649)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  KANEDA Toshiaki (40266606)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  ISHIBASHI Yoshio (00246373)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  OKAMOTO Tomoyoshi (00246381)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  FUTAGAWA Yasuro (70317999)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  IKEUCHI Junji (30056486)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  TAMURA Sigeki (40155263)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  SAKAGUCHI Yujiro (60130168)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  高岡 徹 (30241061)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  岩渕 秀一 (20138720)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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