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KUBO Hirotaka
久保 宏隆
Connect your ORCID iD
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Researcher Number
70119791
External Links
Affiliation (based on the past Project Information)
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2008: 聖徳大学, 人文学部, 教授
2002: 東京慈恵会医科大学, 医学部, 助講師
1999 – 2001: 東京慈恵会医科大学, 医学部, 助教授
1999 – 2000: 東京慈恵会医科大学, 外科学第2教室, 助教授
1992 – 1994: Jikei University school of Medicine, 医学部, 講師
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1993: Jikei Med.Univ.Ch.Resi, 第二外科教室, 講師
1992: 東京慈恵会医科大学医学部, 第2外科, 講師
1991: 東京慈恵会医科大学, 医学部, 助手
1988 – 1991: 東京慈恵会医科大学, 第2外科教室, 講師
1989: Lecturer, The Second Department of Surgery, The Jikei University School of Medicine., 第二外科, 講師
1988: 東京慈恵会医科大学, 医学部第2外科, 講師
1987: 東京慈恵会医科大学, 医学部・第二外科, 講師
1987: 東京慈恵会医科大学, 第二外科教室, 講師
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Review Section/Research Field
Principal Investigator
Digestive surgery
/
General surgery
Except Principal Investigator
Digestive surgery
/
Eating habits, studies on eating habits
/
General surgery
Keywords
Principal Investigator
プリン代謝 / ストレス潰瘍 / 尿酸 / フリ-ラジカル / フリーラジカル / キサンチンオキシダーゼ / ヒポキサンチン / キサンチン / アロプリノール / 胃粘膜防御因子
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/ 組織内ヒポキサンチン / 組織内キサンチン / 胃粘膜微小循環 / 胃粘膜防御因子・ラジカル / 組織内尿酸値 / キサンチン・オキシ-ゼ / キサンチン・オキシ-ゼ抑制剤 / ラジカル阻止剤 / stress ulcer / radical / purine metabolism / xanthine oxidase / hypoxanthine / xanthine / uric acid / 肝細胞癌(hepatocellular carcinoma) / グルタミン代謝(glutamine metabolism) / ミトコンドリ酸化的リン酸化能(mitochondrial oxydative phosphorylation) / amidophosphoribosytransferase活性 / Hypoxanthine / Xanthine / 尿酸(uric acid) / グルタミン / 肝細胞癌 / グルタミン代謝 / グルタミン酸 / グルタミン合成酵素 / グルタミン分解酵素 / ミトコンドリア酸化的リン酸化 / DAB肝癌 / 乳癌ホルモン療法 / 乳癌細胞 / アポトーシス / 抗エストロゲン薬 / 感受性試験 / ミトコンドリア呼吸系酵素 / エストロゲン / 乳癌ホルモン治療 / 抗エストロゲン / エストゴゲン受容体 / Breast cancer / Hormon therapy / Estrogen / Apotpsis / Antiestorogen / Tamoxifen / DNA damege / Mitochondrial respiration / Caspase-3 / 高カロリ-輸液 / 胃粘膜ムコ物質 / ヘキソサミン / 胃粘膜増殖細胞帯 / 胃粘膜ー粘液関門 / 粘膜下血流 / 1.高カロリー輸液 / 2.ストレス潰瘍 / 3.胃粘膜ムコ物質 / 4.ヘキソサミン / 5.胃粘膜増殖細胞帯 / 6.胃粘膜ー粘液関門 / STRESS ULCER / TPN ADMINISTRATION / GASTRIC MUCOSAL MUCOIDS / HEXIOSAMINE / PURUIC METABOLISM / URIC ACID / GENERATIVE CELL ZONE IN GASTRIC MUMOSA / DEFENSIVE MUCAS-MUCOSAL BARRIER
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Except Principal Investigator
プリン代謝 / LH-RH analogue / Tamoxifen / 急性の膵炎 / フリ-ラジカル / キサンチンオキシダ-ゼ / 組織内尿酸 / 脂肪酸 / アディポネクチン / 培養細胞 / PCR / トランス脂肪酸 / PPAR / 小腸粘膜 / 活性酸素 / 虚血 / ギサンチンオキシターゼ / キサンチンオキシターゼ / 小腸移植 / 粘膜障害 / intestinal mucosa / free radical / ischemia / purine metabolism / xanthine oxidase / 骨粗鬆症 / LH-RHagonist / 閉経 / 骨障害 / Tamaxifen / Osteoporosis / 肝不全 / 経腸栄養 / 遺伝子治療 / アデノウイルス / アラツウイルス / Liver Failure / Enteral Nutrution / Gene Therapy / Adenovirus / ストレス潰瘍 / potentia1 defference / 胃粘膜血流 / 防御因子 / 攻撃因子 / 水浸拘束ストレス潰瘍モデル / 閉塞性黄疽モデル / Potentia1 Difference(PD) / ガストリンレセプタ-アンタゴニスト / H_2ーレセプタ-アンタゴニスト / 水浸拘束ストレスモデル / 閉塞性黄疸モデル / PD pH粘液 / 胃粘膜ヒスタミン / PO / pH / 粘液 / STRESS ULCER / JAUNDICE ULCER / AGGRESIVE FACTOR / DEFENSIVE FACTOR
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Research Projects
(
10
results)
Co-Researchers
(
17
People)
Project Start Year (Newest)
Project Start Year (Oldest)
Analysis of induction mechanism of hypoadiponectinemia by trans-fatty acids.
Principal Investigator
KNOU Kazutaka
Project Period (FY)
2008 – 2010
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Eating habits, studies on eating habits
Research Institution
Seitoku University
The Trial of Gene Therapy Using an Enteral Nutrition for the Treatment of Liver.
Principal Investigator
OKAMOTO Tomoyoshi
Project Period (FY)
2000 – 2003
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Digestive surgery
Research Institution
JIKEI UNIVERSITY SCHOOL OF MEDICINE
Establishment of a short term selection methodes of anti-estogenic drugs fitted for individual breast cancer case using apoptosis as a marker.
Principal Investigator
Principal Investigator
KUBO Hirotaka
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
General surgery
Research Institution
Jikei University school Medicine
THE EFFECT OF LH-RH ANALOGUE OR/AND TAMOXIFEN ON BONE IN RATS
Principal Investigator
SUZUKI Yutaka
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
General surgery
Research Institution
JIKEI UNIVERSITY SCHOOL OF MEDICINE
肝細胞癌におけるエネルギー代謝(グルタミン、プリン代謝より)特性における実験的研究
Principal Investigator
Principal Investigator
久保 宏隆
Project Period (FY)
1993 – 1994
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Digestive surgery
Research Institution
Jikei University School of Medicine
Experiments in the effect of ischemic-reperfusion injury and regeneration of the mucosa in small bowel transplantation
Principal Investigator
KASIWAZAKI Osamu
Project Period (FY)
1992 – 1993
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Digestive surgery
Research Institution
Jikei Medical Univ.
急性膵炎発生メカニズムにおけるプリン代謝面からの実験的検討(特にキサンチンオキシダ-ゼ活性の関与について)
Principal Investigator
YOSHII Shuji
Project Period (FY)
1991
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Digestive surgery
Research Institution
Jikei University School of Medicine
RELATIONSHIP BETWEEN STRESS ULCER FORMATION AND RADIKAL(Study from Purine Metabolism)
Principal Investigator
Principal Investigator
KUBO Hirotaka
Project Period (FY)
1990 – 1992
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Digestive surgery
Research Institution
Jikei University school of Medicine
Causing mechanism and treatment for stress ulcer
Principal Investigator
IKEUCHI Junji
Project Period (FY)
1987 – 1989
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Digestive surgery
Research Institution
Jikei University School of Medicine
EXPERIMENTAL STUDY ON EFFECTS OF TPN FOR PREVENTION OF STRESS ULCER OCCURRENCE
Principal Investigator
Principal Investigator
KUBO Hirotaka
Project Period (FY)
1987 – 1989
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Digestive surgery
Research Institution
Jikei University School of Medicine
# of Projects (Dsc)
# of Projects (Asc)
1.
YOSHII Shuji
(50200928)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
2.
HORI Noriya
(20199524)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
3.
TABATA Yasuhiro
(20256415)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
4.
KNOU Kazutaka
(70111507)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
5.
TUDA Naoya
(50246419)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
6.
KASIWAZAKI Osamu
(20056518)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
7.
SUZUKI Yutaka
(20241060)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
8.
田部井 功
(50266649)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
9.
KANEDA Toshiaki
(40266606)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
10.
ISHIBASHI Yoshio
(00246373)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
11.
OKAMOTO Tomoyoshi
(00246381)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
12.
FUTAGAWA Yasuro
(70317999)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
13.
IKEUCHI Junji
(30056486)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
14.
TAMURA Sigeki
(40155263)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
15.
SAKAGUCHI Yujiro
(60130168)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
16.
高岡 徹
(30241061)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
17.
岩渕 秀一
(20138720)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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