YONEHARA Norifumi 米原典史

… Alternative Names

米原典文ヨネハラノリフミ

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Researcher Number	70124534
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2013: 奥羽大学, 歯学部, 教授 2006 – 2010: 奥羽大学, 薬学部, 教授 2006: Ohu University, The School of Pharmaceutical Sciences, Professor, 薬学部, 助教授 2000 – 2005: Graduate School of Dentistry Osaka University Associate Professor, 大学院・歯学研究科, 助教授 2002: 大阪大学, 歯学研究科, 助教授 … More 1993 – 1999: 大阪大学, 歯学部, 講師 1986 – 1992: 大阪大学, 歯学部, 助手 1986: 阪大, 歯学部, 助手 Less
Review Section/Research Field	Principal Investigator Functional basic dentistry / Functional basic dentistry Except Principal Investigator Functional basic dentistry / Morphological basic dentistry / Morphological basic dentistry / Pain science / Pain science
Keywords	Principal Investigator アロディニア / 一酸化窒素 / 下歯槽神経 / 三叉神経感覚核 / 歯髄刺激 / サブスタンスP / 疼痛 / 痛覚過敏 / マイクロダイアリシス / グルタミン酸 … More / NADPH-diaphorase / NMDA / Allodynia / Trigeminal nucleus caudalis / Nitric oxide / 一次知覚神経 / Substance P / 鍼刺激 / エンケファリン / 神経因性疼痛 / 神経栄養因子 / 熱侵害刺激 / 逃避行動 / 求心路遮断性疼痛 / ノルアドレナリン / 高速クロマトグラフィー電気検出器 / von Freyフィラメント / 高速クロマトグラフィ-電気化学検出器 / アジュバント / ラット足蹠 / N^ω-nitro-L-arginine methyl ester / アジュバンド / NO / nociception / dorsal horn / N^<omega>-L-arginine methyl ester / 三叉神経核 / 抜髄 / 末梢神経損傷 / Deafferentation pain / Inferior alveolar nerve / 末梢神経 / 三叉神経脊髄路核 / 神経損傷 / ニューロパシー / グルタミン酸受容体 / 疼痛行動 / cFos / Glutamate / Peripheral nerve injury / Microdialysis / Nerve injury / 三又神経脊髄路核 / push-pull cannula / 潅流法 / サブスタンスp / オピリオイド / セロトニン / substance P / 第一次求心性線維 / 三叉神経脊髄路核尾側亜核 / 歯髄電気刺激 / morphine / met-enkephalin / Primary sensory neurons / Brain-stem trigeminal sensory nuclear complex / Tooth pulp stimulation / Push-pull perfusion cannula system / Opioids / 微小循環動態 / レ-ザ-ドップラ-血流計 / 口唇 / 足蹠皮膚 / 炎症反応 / 一次求心性線維 / 血流量 / Primary afferent neurons / Microcirculatory hemodynamics / Laser doppler flowmeter / Oral region / Hind paw … More Except Principal Investigator サブスタンスP / 疼痛 / 一酸化窒素 / 三叉神経 / NADPH-diaphorase / c-Fos / 三叉神経感覚核 / 神経因性疼痛 / GABA / 歯髄刺激 / 口腔・顔面 / ブラジキニン / エンケファリン / 歯髄 / Bradykinin / trigeminal nucleus / 口腔感覚 / 体性局在 / nitric oxide / pain / 味覚 / カテプシンB / 三叉神経脊髄路核 / 三叉神経節 / 痛覚制御 / Substance P / 三叉神経核 / 孤束核 / 感覚 / 運動 / Nitric oxide / ニトロ化タンパク質 / ビククリン / Neuropathic Pain / 三叉神経脊髄路核尾側亜核 / セロトニン / モルヒネ / グルタミン酸 / アスパラギン酸 / C-線維 / 侵害受容ニューロン / ニューロキニン受容体 / γアミノ酪酸 / IB-4 / GABA受容体 / Saporin / アセチルコリン / 坐骨神経結紮モデル / マウス / Spared Nerve Injury / コリン作動性神経 / 機械性侵害受容体 / ショウジョウバエ / カエル / TRPV1 / TRPV4 / TRPチャネル / 機械刺激 / 味覚神経 / 機械刺激受容体 / 痛覚受容体 / 歯髄線維芽細胞 / desーArg9ーブラジキニン / アルギニン / カルシウム / タンパク質りん酸化 / エンケファリン産生 / des‐Arg9‐ブラジキニン / エンケフアリン前駆体タンパク / エンケフアリン産生 / desーArg^<9ー>ブラジキニン / プロテインキナ-ゼ / 線維芽細胞 / エンケファリン産生酵素 / エンケファリン前駆体タンパク / システイン / ライソソ-ム酵素 / Tooth Pulp / Fibroblasts / Des-Arg^9-Bradykinin / Arginine / Enkephalins / Cathepsin B / Protein Phosphorylation / カルシウムチャネル / ペプチド / Enkephalin / Dental Pulp / Calcium Channel / Morphine / Serotonin / Trigeminal Sensory Nuclear / NADPH-d / 口腔顔面 / 成長 / 三叉神経知覚核 / 孤側核 / 胎生期 / 舌神経 / ラット / Solitary tract nucleus / Oro-facial / Sensory / Motor / Development / 神経再生 / 細胞毒性 / 個体発生 / sensory / motor / regeneration / neurotoxicity / ニトロ化たんぱく質 / 痛覚 / アロディニア / ペルオキシナイトライト / 脊髄背側路核 / trigeminal nerve / protein nitration / substance P / allodynia / peroxynitrite / trigeminal nucleus caudalis / 口腔 / 顔面 / カルシウム結合蛋白 / 一酸化窒素合成酵素 / 大脳皮質 / アンチセンス / ムシモル / oral sensation / somatotopy / 歯周炎 / 炎症刺激 / 情報伝達 / 細胞死 / 培養細胞 / 神経幹細胞 / 歯肉炎 / PPARγ / 核移行型受容体 / 転写制御因子 / peri-gingivitis / nitrated protein / inflammation / signal transduction / apotosis (cell death) / cultured cells / neural stem cells / 三叉神経降圧反応 / 低体温療法 / 神経毒性 / 感覚制御 / ホルマリンテスト / 顔面皮膚感覚 / Trigeminal Depressor Response / Pain / Nitric Oxide / Hypothermia / Neurotoxicity / Sensory Regulation / Oro-Facial / 神経因性性疼痛 / 侵害受容器 / 機械受容器 / ニューロキニン1 / γアミノ酪酸受容体 / γアミノ酪酸A受容体 / 下行性制御 / SP-サポリン / 性差 / Nociceptors / Mechanoreceptors / Neurokinin-1 / Bicuculline / Trigeminal System / 歯痛 / メチオニン・エンケファリン / ロイシン・エンケファリン / 侵害刺激 / Sudstance P / Metーenkephalin / 三又神経節 / Leuーenkephalin含有細胞 / Leuーenkephalin受容体 / 下行性抑制系 / suosthnce P / serotonin / 歯髄侵害刺激 / アジュバント関節炎 / enkephalin / bradykinin / Dental pain / Methionine enkephalin / Leucine enkephalin / Trigeminal ganglion / Trigeminal nucleus caudalis Less

Identification of frog cutaneous nociceptors and functional analysis of them using transgenic flies
- Principal Investigator
  
  FURUYAMA Akira
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pain science
- Research Institution
  Ohu University
Involvement of neurotrophic factors in the development of neuropathic pain evoked by the loose-ligation of peripheral nervesPrincipal Investigator
- Principal Investigator
  
  YONEHARA Norifumi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Ohu University
Study for mechanism of orofacial neuropathic pain
- Principal Investigator
  
  TAKEMURA Motohide
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Osaka University
The role of cholinergic neurons on the manifestation and retention of experimental neuropathic pain model in mice
- Principal Investigator
  
  ABE Kenji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Ohu University
Study on the role of the primary afferent fibers in thedevelopment/maintenance of the intractable pain in the oro-facial regionPrincipal Investigator
- Principal Investigator
  
  YONEHARA Norifumi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Ohu University
Study on the mechanisms of oro-facial and temporomandibular joint neuropathic pain control in the central nervous system
- Principal Investigator
  
  TAKEMURA Motohide
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Osaka University
Study on the local neural circuitry involved in the oro-facial sensory expression
- Principal Investigator
  
  TAKEMURA Motohide
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Osaka University
Effect of protein nitration on peri-gingivitis and inflammatory regulation mechanism involving nitration and de-nitration.
- Principal Investigator
  
  KAMISAKI Yoshinori
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Osaka University
Direct and indirect effects of nitric oxide on nociceptive signal transduction at the trigeminal nucleus caudalis and mechanism for the regulation
- Principal Investigator
  
  KAMISAKI Yoshinori
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Osaka University
Morpho-functional study of trigeminal neurons in the brain stem that are involved in oro-facial sensori-motor function.
- Principal Investigator
  
  TAKEMURA Motohide
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Osaka University
Alterations of neuronal response and transcription factors in the trigeminal nucleus following deafferentation painPrincipal Investigator
- Principal Investigator
  
  YONEHARA Norifumi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Osaka University
Morpho-functional study of nitric oxide synthase-positive neurons in the brain stem that are involved in oral sensori-motor function.
- Principal Investigator
  
  TAKEMURA Motohide
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Osaka University
INVOLVEMENT OF NITRIC OXIDE IN MAINTAINING AND FACILITATING THE HYPERALGESIA ASSOCIATED WITH CHRONIC NOCICEPTION IN THE SITE OF THE FIRST SYNAPTIC RELAY OF THE PAIN PATHWAYPrincipal Investigator
- Principal Investigator
  
  YONEHARA Norifumi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Osaka University
Morphological and functional studies on NO producing neurons in the brainstem involved in pral sensori-motor functions
- Principal Investigator
  
  TAKEMURA Motohide
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Osaka University
侵害刺激に対する三叉神経主感覚核並びに脊髄路核での応答性と伝達物質についてPrincipal Investigator
- Principal Investigator
  
  米原典史
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
侵害刺激に対する三叉神経主感覚核並びに脊髄路核での応答性と伝達物質について
- Principal Investigator
  
  猪木令三
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
侵害刺激に対する三叉神経主感覚核並びに脊髄路核での応答性と伝達物質について
- Principal Investigator
  
  INOKI Reizo
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
MODULATION OF DENTAL PAIN BY ENDOGENOUS PEPTIDES
- Principal Investigator
  
  INOKI Reizo
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Osaka University
Mechanism of Opioid Peptide Production in Cultured Fibroblasts of The Tooth Pulp.
- Principal Investigator
  
  KUDO Teruo
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Osaka University
Study on the involvement of primary afferent neurons in microcirculatory dynamics in oral regionPrincipal Investigator
- Principal Investigator
  
  YONEHARA Norifumi
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Osaka University
COMPREHENSIVE STUDIES ON THE TRANSDUCTION AND MODULATION OF DENTAL PAIN IN THE CENTRAL NERVOUS SYSTEM AND IN THE PERIPHERY.
- Principal Investigator
  
  INOKI Reizo
- Project Period (FY)
  1986 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  OSAKA UNIVERSITY
Study on the presence of the specific substances participating in the transmission of particular kinds of sensationPrincipal Investigator
- Principal Investigator
  
  YONEHARA Norifumi
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Osaka University

All 2012 2011 2010 2009 2008 2007 2006 2004 2003 2002 Other

All Journal Article Presentation Book Patent

[Book] Pain Research and Treatment (vol.2012, Article ID 915706)2012
- Author(s)
  You-Hong Jin, Motohide Takemura, Akira Furuyama and Norifumi Yonehara
- Total Pages
  8
- Data Source
  KAKENHI-PROJECT-23659321
[Book] Pharmacology2012
- Author(s)
  You-Hong Jin, Motohide Takemura, Akira Furuyama and Norifumi Yonehara
- Publisher
  INTECH
- Data Source
  KAKENHI-PROJECT-23659321
[Book] 分子神経薬理学(臨床神経科学の基礎)第19章 Pain2004
- Author(s)
  米原典史
- Total Pages
  17
- Publisher
  西村書店
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591929
[Journal Article]2012
- Author(s)
  You-Hong Jin, Motohide Takemura, Akira Furuyama, Norifumi Yonehara
- Journal Title
  
  Pain Research and Treatment
  
  Volume: vol.2012, Article ID 915706 Pages: 8-8
- Data Source
  KAKENHI-PROJECT-23659321
[Journal Article] Peripheral Glutamate Receptors Are Required for Hyperalgesia Induced by Capsaicin2011
- Author(s)
  You-Hong Jin, Motohide Takemura, Akira Furuyama and Norifumi Yonehara
- Journal Title
  
  Pain Research and Treatment
  
  Volume: 2012 Pages: 1-8
- DOI
  10.1155/2012/915706
- Data Source
  KAKENHI-PROJECT-23659321
[Journal Article] 神経障害性疼痛(慢性痛)におけるグルタミン酸とその受容体の役割2010
- Author(s)
  米原典史、古山昭, (2人中1番目)
- Journal Title
  
  医薬品相互作用研究会
  
  Volume: 33 Pages: 81-90
- Data Source
  KAKENHI-PROJECT-20592183
[Journal Article] c-Fos expression within the L5 spinal cord dorsal horn after spinal nerve ligation in rats2010
- Author(s)
  Y.H.Jin, M Takemura, N.Yonehara, (7人中7番目)
- Journal Title
  
  Neural Regeneration Res
  
  Volume: 5 Pages: 450-455
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592183
[Journal Article] 神経障害性疼痛(慢性痛)におけるグルタミン酸とその受容体の役割2010
- Author(s)
  米原典史、古山昭 (2人中1番目)
- Journal Title
  
  医薬品相互作用研究会 33
  
  Pages: 81-90
- Data Source
  KAKENHI-PROJECT-20592183
[Journal Article] c-Fos expression within the L5 spinal cord dorsal horn after spinal nerve ligation in rats2010
- Author(s)
  Y.H. Jin, M. Takemura, N.Yonehara(7人中7番目)
- Journal Title
  
  Neural Regeneration Res 5
  
  Pages: 450-455
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592183
[Journal Article] Capsaicin-induced glutamate release is implicated in nociceptive processing through activation of ionotropic glutamate receptors and group I metabotropic glutamate receptor in primary afferent fibers2009
- Author(s)
  Y.H. Jin, M.Takemura, A.Furuyama, N.Yonehara (6人中6番目)
- Journal Title
  
  J. Pharamacol. Sci 109
  
  Pages: 233-241
- NAID
  10025734446
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592183
[Journal Article] Effects of systemic bicuculline or morphine on formalin-evoked pain-relatedbehaviour and c-Fos expression intrigeminal nuclei after formalininjection into the lip or tongue in rats2009
- Author(s)
  Sugiyo S, Uehashi D, Satoh F, Abe T, Yonehara N, Kobayashi M, Takemura M
- Journal Title
  
  Exp Brain Res 196
  
  Pages: 229-237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592108
[Journal Article] Effects of systemic bicuculline or morphine on formalin-evoked pain-related behaviour and c-Fos expression in trigeminal nuclei after formalin injection into the lip or tongue in rats2009
- Author(s)
  N.Yonehara, M.Takemura (7人中5番目)
- Journal Title
  
  Exp. Brain Res 196
  
  Pages: 229-237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592183
[Journal Article] Effects of systemic bicuculline or morphine on formalin-evoked pain-related behaviour and c-Fos expression in trigeminal nuclei after formalin injection into the lip or tongue in rats2009
- Author(s)
  Sugiyo S, Uehashi D, Satoh F, Abe T, Yonehara N, Kobayashi M, Takemura M.
- Journal Title
  
  Exp Brain Res 196
  
  Pages: 229-237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592183
[Journal Article] Capsaicin-induced glutamate release is implicated in nociceptive processing through activation of ionotropic glutamate receptors andgroup I metabotropic glutamate receptor in primary afferent fibers.2009
- Author(s)
  Jin Y-H, Yamaki F, Takemura M, Koike Yuichi, Furuyama A, Yonehara N
- Journal Title
  
  J Pharmacol Sci 109
  
  Pages: 233-241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592108
[Journal Article] Capsaicin-induced glutamate release is implicated in nociceptive processingthrough activation of ionotropicglutamate receptors and group Imetabotropic glutamate receptor inprimary afferent fibers2009
- Author(s)
  Jin Y-H, Yamaki F, Takemura M, Koike Yuichi, Furuyama A, Yonehara N
- Journal Title
  
  J Pharmacol Sci 109
  
  Pages: 233-241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592108
[Journal Article] Capsaicin-induced glutamate release is implicated in nociceptive processing through activationa of ionotropic glutamate recptors and group I metabotropic glutamate receptor in primary afferent fibers2009
- Author(s)
  Jin Y-H, Yamaki F, Takemura M, Koike Y, Furuyama A, Yonehara N.
- Journal Title
  
  J Pharmacol Sci 109
  
  Pages: 233-241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592183
[Journal Article] Intraplantar morphine prevents the decrease of the rate of thermal withdrawal latencies evoked by glutamate and capsaicin2009
- Author(s)
  M. Takemura, N.Yonehara (5人中5番目)
- Journal Title
  
  Acta Acad Med Jiangxi 48
  
  Pages: 24-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592183
[Journal Article] 痛みの情報伝達とクルクミン酸受容体2008
- Author(s)
  八巻史子, 米原典史
- Journal Title
  
  小児科 49(11)
  
  Pages: 1445-1453
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592183
[Journal Article] 痛みの情報伝達とグルタミン酸受容体2007
- Author(s)
  八巻史子、米原典史
- Journal Title
  
  ペインクリニック 28
  
  Pages: 1523-1534
- Data Source
  KAKENHI-PROJECT-18592030
[Journal Article] 痛みとグルタミン酸受容体2007
- Author(s)
  米原典史、八巻史子
- Journal Title
  
  麻酔 56
- Data Source
  KAKENHI-PROJECT-18592030
[Journal Article] 痛みとグルタミン酸受容体2007
- Author(s)
  米原典史, 八巻史子
- Journal Title
  
  麻酔、56増刊
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592030
[Journal Article] Alteration of sensitivity of ionotropic glutamate receptors and tachy kinin receptors in spinal cord contributeto development and maintenance of nerve injury-evoked neuropathic pain2006
- Author(s)
  Yoshimura M., Yonehara N.
- Journal Title
  
  Neuroscience Res. 56
  
  Pages: 21-28
- Data Source
  KAKENHI-PROJECT-18592030
[Journal Article] Mechanisms of orofacial pain control in the central nervous system.2006
- Author(s)
  Takemura M., Sugiyo S., Moritani M., Kobayashi M., Yonehara N.
- Journal Title
  
  Archives of Histology and Cytology 69
  
  Pages: 79-100
- NAID
  10018151460
- Data Source
  KAKENHI-PROJECT-18592030
[Journal Article] Effect of morphine on the release of excitatory amino acids in the rathind instep : Pain is modulated by the interaction between the peripheral opioid and glutamate systems.2006
- Author(s)
  You Hong Jin, Hiroaki Nishioka, Ken Wakabayashi, Fujita T, Yonehara N
- Journal Title
  
  Neuroscience (In press)
- Data Source
  KAKENHI-PROJECT-17591906
[Journal Article] Effect of morphine on the release of excitatory amino acids in the rathind instep : Pain is modulated by the interaction between the peripheral opioid and glutamate systems.2006
- Author(s)
  Jin YH, Nishioka W, Wakabayashi K, Fujita T, Yonehara N.
- Journal Title
  
  Neuroscience 138
  
  Pages: 1329-1339
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591906
[Journal Article] Mechanisms of orofacial pain control in the central nervous system.2006
- Author(s)
  Takemura M, Sugiyo S, Moritani M, Kobayashi M, Yonehara N.
- Journal Title
  
  Archives of Oral Biology 69
  
  Pages: 79-100
- NAID
  10018151460
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591906
[Journal Article] Effect of morphine on the release of excitatory amino acids in the rat hind instep: Pain is modulated by the interactionbetween the peripheral opioid and glutamate systems2006
- Author(s)
  Jin Y-H., Nishioka H., Wakabayashi K., Fujita T.and Yonehara N.
- Journal Title
  
  Neuroscience 138
  
  Pages: 1329-1339
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592030
[Journal Article] Mechanisms of orofacial pain control in the central nervous system.2006
- Author(s)
  Takemura M, Sugiyo S, Moritani M, Kobayashi M, Yonehara N
- Journal Title
  
  Arch Histol Cytol 69
  
  Pages: 79-100
- NAID
  10018151460
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591906
[Journal Article] Alteration of sensitivity of ionotropic glutamate receptors and tachykinin receptors in spinal cord contribute to development and maintenance of nerve injury-evoked neuropathic pain2006
- Author(s)
  Yoshimura M.and Yonehara N.
- Journal Title
  
  Neuroscience Res 56
  
  Pages: 21-28
- NAID
  10018771702
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592030
[Journal Article] Effect of morphine on the release of excitatory amino acids in the rat hind instep : Pain is modulated by the interactionbetween the peripheral opioid and glutamate systems2006
- Author(s)
  Jin, Y-H., Nishioka, H., Wakabayashi, K., Fujita, T., Yonehara, N
- Journal Title
  
  Neuroscience 138
  
  Pages: 1329-1339
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592030
[Journal Article] Alteration of sensitivity of ionotropic glutamate receptors and tachykinin receptors in spinal cord contribute to development and maintenance of nerve injury-evoked neuropathic pain.2006
- Author(s)
  Yoshimura M.Yonehara N.
- Journal Title
  
  Neuroscience Res. 56
  
  Pages: 21-28
- NAID
  10018771702
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591906
[Journal Article] Alteration of sensitivity of ionotropic glutamate receptors and tachykinin receptors in spinal cord contribute to development and maintenance of nerve injury-evoked neuropathic pain2006
- Author(s)
  Yoshimura, M., Yonehara, N
- Journal Title
  
  Neuroscience Res 56
  
  Pages: 21-28
- NAID
  10018771702
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592030
[Journal Article] Alteration in sensitivity of ionotropic glutamate receptors and tachykinin receptors in spinal cord contribute to development and maintenance of nerve injury-evoked neuropathic pain.2006
- Author(s)
  Yoshimura M, Yonehara N
- Journal Title
  
  Neuroscience Research 56・1
  
  Pages: 21-28
- NAID
  10018771702
- Data Source
  KAKENHI-PROJECT-17591906
[Journal Article] Effect of morphine on the release of excitatory amino acids in the rathind instep : Pain is modulated by the interaction between the peripheral opioid and glutamate systems.2006
- Author(s)
  Jin YH, Nishioka H, Wakabayashi Ken, FujitaT. Yonehara N.
- Journal Title
  
  Neuroscience 138
  
  Pages: 1329-1339
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591906
[Journal Article] Mechanisms of orofacial pain control in the central nervous system.2006
- Author(s)
  Takemura M, Sugiyo S, Moritani M, Kobayashi M, Yonehara N
- Journal Title
  
  Archives of Histology and Cytology 69
  
  Pages: 79-100
- NAID
  10018151460
- Data Source
  KAKENHI-PROJECT-17591906
[Journal Article] Alteration of sensitivity of ionotropic glutamate receptors and tachykinin receptors in spinal cord contribute to development and maintenance of nerve injury-evoked neuropathic pain.2006
- Author(s)
  Yoshimura M, Yonehara N.
- Journal Title
  
  Neuroscience Res. 56
  
  Pages: 21-28
- NAID
  10018771702
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591906
[Journal Article] Effect of morphine on the release of excitatory amino acids in the rathind instep : Pain is modulated by the interaction between the peripheral opioid and glutamate systems2006
- Author(s)
  You Hong Jin, Hiroaki Nishiok, Ken Wakabayashi, Fujita T., Yonehara N.
- Journal Title
  
  Neuroscience 138
  
  Pages: 2329-1339
- Data Source
  KAKENHI-PROJECT-18592030
[Journal Article] Effect of morphine on the release of excitatory amino acids in the rat hind instep : Pain is modulated by the interaction between the peripheral opioid and glutamate systems.2006
- Author(s)
  Jin YH, Nishioka H, Wakabayashi K, Fujita T, Yonehara N
- Journal Title
  
  Neuroscience 138・4
  
  Pages: 1329-1339
- Data Source
  KAKENHI-PROJECT-17591906
[Journal Article] NO-induced increase of excitatory amino acids level in the trigeminal nucleus caudalis of the rat with tactile hypersensitivity evoked by the loose-ligation of the inferior alveolar nerves.2004
- Author(s)
  米原典史
- Journal Title
  
  モレキュラーメディシン(中山書店) 41
  
  Pages: 676-684
- Data Source
  KAKENHI-PROJECT-15591929
[Journal Article] 痛みとグルタミン酸受容体:特集、痛みの分子メカニズムと臨床2004
- Author(s)
  米原典史
- Journal Title
  
  モレキュラーメディシン(中山書店) 41
  
  Pages: 676-684
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591929
[Journal Article] Glutamate receptors and pain.2004
- Author(s)
  Yonehara, N. et al.
- Journal Title
  
  Molecular Medicine 41
  
  Pages: 676-684
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591929
[Journal Article] The topics of the basic research and the forefront of the treatment concerned with the pain.2004
- Author(s)
  Yonehara, N. et al.
- Journal Title
  
  Molecular Medicine 41
  
  Pages: 638-641
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591929
[Journal Article] Nitric oxide-induced increase of excitatory amino acid levels in the trigeminal nucleus caudalis of the rat with tactile hypersensitivity evoked by the loose-ligation of the inferior alveolar nerves.2004
- Author(s)
  Fujita, T., Kamisaki, Y., Yonehara, N.
- Journal Title
  
  Journal of Neurochemistry 91
  
  Pages: 558-567
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370592
[Journal Article] 痛みにかかわる基礎研究と治療の最前線:特集、痛みの分子メカニズムと臨床2004
- Author(s)
  米原典史
- Journal Title
  
  モレキュラーメディシン(中山書店) 41
  
  Pages: 637-641
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591929
[Journal Article] Involvement of NMDA-nitric oxide pathways in the development of tactile hypersensitivity evoked by the loose-ligation of inferior alveolar nerves in rats.2003
- Author(s)
  Yonehara N
- Journal Title
  
  Brain Research 963・1-2
  
  Pages: 232-243
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591929
[Journal Article] Involvement of NMDA-nitric oxide pathways in the development of tactile hypersensitivity evoked by the loose-ligation of inferior alveolar nerves in rats.2003
- Author(s)
  Yonehara, N. et al.
- Journal Title
  
  Brain Res. 963
  
  Pages: 232-243
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591929
[Journal Article] Involvement of NMDA-nitric oxide pathways in the development of tactile hypersensitivity evoked by the loose-ligation of inferior alveolar nerves in rats.2003
- Author(s)
  Yonehara, N., Kudo, C., Kamisaki, Y.
- Journal Title
  
  Brain Research 963
  
  Pages: 232-243
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370592
[Journal Article] Involvement of the NMDA-nitric oxide pathway in the development of hypersensitivity to tactile stimulation in dental injured rats.2002
- Author(s)
  Yonehara, N., Amano, K., Kamisaki, Y.
- Journal Title
  
  Japanese Journal of Pharmacology 90
  
  Pages: 145-155
- NAID
  130000078432
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370592
[Journal Article] Involvement of the NMDA-nitric oxide pathway in the development of hypersensitivity to tactile stimulation in dental injured rats.2002
- Author(s)
  Yonehara, N.Amano, K., Kamisaki, Y.
- Journal Title
  
  Japanese Journal of Pharmacology 90
  
  Pages: 145-155
- NAID
  130000078432
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370592
[Patent] 血液酸化抑制器具2010
- Inventor(s)
  熊野活行, 山本正雅, 米原典史, 小池勇一
- Industrial Property Rights Holder
  日本システム企画株式会社
- Acquisition Date
  2010-06-11
- Overseas
- Data Source
  KAKENHI-PROJECT-20592183
[Patent] 血液酸化抑制器具2010
- Inventor(s)
  熊野活行、山本正雅、米原典史、小池勇一
- Industrial Property Rights Holder
  日本システム企画株式会社
- Filing Date
  2010-06-11
- Overseas
- Data Source
  KAKENHI-PROJECT-20592183
[Presentation] The effect of capsaicin on the defensive reflexes for thermal and mechanical stimuli in frog2012
- Author(s)
  古山昭、米原典史
- Organizer
  日本比較生理生化学会第34回大会
- Place of Presentation
  神奈川県三浦郡葉山町　総合研究大学院大
- Data Source
  KAKENHI-PROJECT-23659321
[Presentation] カプサイシンの皮下投与により生じるカエルの機械性アロディニア2012
- Author(s)
  古山昭、大須賀謙二、米原典史、宗形芳英
- Organizer
  第54回歯科基礎医学会学術大会
- Place of Presentation
  福島県郡山市　奥羽大学
- Data Source
  KAKENHI-PROJECT-23659321
[Presentation]2012
- Author(s)
  古山昭、大須賀謙二、米原典史、宗形芳英
- Organizer
  第54回歯科基礎医学会学術大会
- Place of Presentation
  郡山
- Data Source
  KAKENHI-PROJECT-23659321
[Presentation]2012
- Author(s)
  Akira furuyama, Norifumi Yonehara
- Organizer
  日本比較生理生化学会第34回大会
- Place of Presentation
  葉山
- Data Source
  KAKENHI-PROJECT-23659321
[Presentation] Biological resonance induced by electromagnetic waves from Yubi-NMR reduces oxidative stress in blood2011
- Author(s)
  山本正雅、小池勇一、熊野活行、米原典史
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20592183
[Presentation] Pharmacokinetic and Pharmacodynamic modeling of denopamine in patients with congestive heart failure2010
- Author(s)
  Koike Y., Yonehara N.
- Organizer
  16^<th> World Congress on Basic and Clinical Pharmacology
- Place of Presentation
  Copenhagen, Denmark
- Data Source
  KAKENHI-PROJECT-20592183
[Presentation] Radiation of electromagnetic waves to a finger using YUBI-MR reduces oxidative stress in blood by electron-transfer via negatively charged water formation.2010
- Author(s)
  山本正雅, 小池勇一, 米原典史
- Organizer
  16^<th> World Congress on Basic and Clinical Pharmacology
- Place of Presentation
  Copenhagen, Denmark
- Data Source
  KAKENHI-PROJECT-20592183
[Presentation] Involvement of glutamate receptors existing in peripheral ending of primary afferent fibers in nociception2010
- Author(s)
  Yonehara N., Koike Y.
- Organizer
  16^<th> World Congress on Basic and Clinical Pharmacology
- Place of Presentation
  Copenhagen, Denmark
- Data Source
  KAKENHI-PROJECT-20592183
[Presentation] Radiation of electromagnetic waves to a finger using YUBI-NMR reduces oxidative stress in blood by electro-transfer via negatively charged water formation2010
- Author(s)
  Yamamoto N., Koike Y., Yonehara N.
- Organizer
  16^<th> World Congress on Basic and Clinical Phannacology
- Place of Presentation
  Copenhagen, Denmark
- Data Source
  KAKENHI-PROJECT-20592183
[Presentation] Pharmacokinetic and Pharmacodynamic modeling of denopamine in patients with congestive heart failure.2010
- Author(s)
  小池勇一, 米原典史
- Organizer
  16^<th> World Congress on Basic and Clinical Pharmacology
- Place of Presentation
  Copenhagen, Denmark
- Data Source
  KAKENHI-PROJECT-20592183
[Presentation] Involvement of glutamate receptors existing in peripheral ending of primary afferent fibers in nociception.2010
- Author(s)
  米原典史, 小池勇一
- Organizer
  16^<th> World Congress on Basic and Clinical Pharmacology
- Place of Presentation
  Copenhagen, Denmark
- Data Source
  KAKENHI-PROJECT-20592183
[Presentation] カエル皮膚侵害受容器のトランスダクション機構におけるカプサイシン受容体の関与2009
- Author(s)
  古山昭、米原典史
- Organizer
  日本ペインクリニック学会第43回大会、第31回日本疼痛学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20592183
[Presentation] Involvement of peripheral glutamate receptors in capsaicin-induced nociceptive processing2009
- Author(s)
  F Yamaki, Y Koike, Y Takata, N Yonehara
- Organizer
  第82回日本薬理学会総会(横浜)
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20592183
[Presentation] カエル皮膚痛侵害受容器のトランスダクション機構におけるカプサイシン受容体の関与2009
- Author(s)
  古山昭、米原典史
- Organizer
  日本ペインクリニック学会第43回大会、第31回日本疼痛学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20592183
[Presentation] (2008) Intra cisterna magna and rostral ventromedial medullainjection of anti-serotonintransporter-saporin bidirectionallychanged formalin-induced pain relatedbehaviour and c-Fos expression in themedullary dorsal horn in rats2008
- Author(s)
  Sugiyo S., Uehashi D., Masawaki A., Ohyamaguchi A., Abe T., Yonehara N.,Takemura M.
- Organizer
  Annual meetings of Society for Neuroscience
- Place of Presentation
  Washington DC
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-19592108
[Presentation] Intra cisterna magna and rostral ventromedial medulla injection of anti-serotonin transporter-saporin bidirectionally changed formalin-induced pain related behavior and c-Fos expression in the medullary dorsal horn in rats.2008
- Author(s)
  Sugiyo S., Uehashi D., Masawaki A., Ohyamaguchi A., Abe T., Yonehara N., Takemura M.
- Organizer
  Annual meetings of Society for Neuroscience
- Place of Presentation
  Washington DC
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-19592108
[Presentation] グルタミン酸受容体と疼痛2007
- Author(s)
  米原典史
- Organizer
  日本麻酔学会第54回学術集会
- Place of Presentation
  札幌
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592030
[Presentation] Changes in sensitivity of glutamate receptors atthe peripheral endings of the nociceptivefivers following nerve injury2007
- Author(s)
  F Yamaki, A Furuyama, M Takemura, Yuichi Koike, N Yonehara
- Organizer
  30th Annual Meeting of Japan NeuroscienceSociety
- Place of Presentation
  Pacifico Yokohama
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-19592108
[Presentation] 痛みとグルタミン酸
- Author(s)
  米原典史
- Data Source
  KAKENHI-PROJECT-18592030

1. TAKEMURA Motohide (70192169)

# of Collaborated Projects: 11 results

# of Collaborated Products: 17 results
2. SAITO Kihachi (40110788)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. MAEDA Sadaaki (00135732)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
4. KUDO Teruo (10028805)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
5. INOKI Reizo (60028719)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. SUGIYO Shinichi (90397688)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
7. FURUYAM Akira (80364454)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
8. MORITANI Masayuki (80303981)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
9. KOIKE Yuiti (90109421)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
10. KAKU Tetsuki (50126570)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. WADA Kouichirou (90263467)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. KOBAYASHI Masayuki (00300830)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
13. ABE Kenji (60405991)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. NOJIMA Hiroshi (50208344)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. NAGASE Yoshitaka (50252698)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. KAMISAKI Yoshinori (40116017)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
17. SAEKI Makio (30273692)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. YOKOSE Satoshi (90245803)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. SAITO Shigeru (50422069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. ISONO Kunio (70124550)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. MASUZAWA Toru (40199691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. KANG Youngnam (50177755)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. YOSHIDA Atsushi (90201855)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. TAKADA Yoshinobu (40119590)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 八巻史子 (60433562)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
26. 赤井三千男 (20028715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YONEHARA Norifumi 米原 典史

米原 典文 ヨネハラ ノリフミ

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Involvement of neurotrophic factors in the development of neuropathic pain evoked by the loose-ligation of peripheral nervesPrincipal Investigator

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Study on the role of the primary afferent fibers in thedevelopment/maintenance of the intractable pain in the oro-facial regionPrincipal Investigator

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Alterations of neuronal response and transcription factors in the trigeminal nucleus following deafferentation painPrincipal Investigator

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INVOLVEMENT OF NITRIC OXIDE IN MAINTAINING AND FACILITATING THE HYPERALGESIA ASSOCIATED WITH CHRONIC NOCICEPTION IN THE SITE OF THE FIRST SYNAPTIC RELAY OF THE PAIN PATHWAYPrincipal Investigator

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侵害刺激に対する三叉神経主感覚核並びに脊髄路核での応答性と伝達物質についてPrincipal Investigator

YONEHARA Norifumi 米原典史

米原典文ヨネハラノリフミ