TACHIBANA Kazuo 橘和夫

Researcher Number	70142081
External Links
Affiliation (based on the past Project Information) *help	2004 – 2006: 東京大学, 大学院・理学系研究科, 教授 1993 – 2000: 東京大学, 大学院・理学系研究科, 教授 1996 – 1997: 東京大学, 大学院・理学研究科, 教授 1991 – 1994: 東京大学, 理学部, 教授
Review Section/Research Field	Principal Investigator Living organism molecular science / 天然物有機化学 Except Principal Investigator Bioorganic chemistry / 分離・精製・検出法 / 天然物有機化学
Keywords	Principal Investigator 脂質二重膜 / helical structure / photo-affinity labeling / Gambierol / Suzuki cross coupling / lipid bilayer / membrane protein / polycyclic ether / marine toxin / 分子認識機構 … More / 螺旋構造 / 光親和性標識 / ガンビエロール / 鈴木クロスカップリング / 膜タンパク質 / ポリ環状エーテル / 海産毒 / 分子認識 / ヘキサゴナル相 / コンカナバリンA / ブレビトキシン / ポリセオナミドB / 水晶発振子 / ガングリオシド / ナトリウムチャネル / リン脂質膜 / イエッソトキシン / ポリセオナミド / シガトキシン / マイトトキシン / ブレベトキシン / 有機合成化学 / 生物有機化学 / 天然物有機化学 / 天然物化学 / 海洋天然物 / 超活性 … More Except Principal Investigator maitotoxin / マイトトキシン / NMR / GM3 / GM1 / membrane proteins / ガングリオシド / ポリエーテル化合物 / 超分子 / 生物活性 / 天然有機化合物 / amphidinol / natural products / conformation / configuration / J values / spin coupling constants / 鎖状構造 / アンフィジノール / 天然物 / 立体配座 / 立体配置 / J値 / スピン結合定数 / oligosaccharide / photoaffinity labeling / ganglioside / pharmacological action / 海洋天然物 / 作用標的分子 / アンフォテリシンB / ポリエン化合物 / オリゴ糖 / 膜タンパク質 / 光親和標識 / 薬理作用解析 / ciguatoxin / polyether compounds / 赤血球膜 / シガトキシン / 膜蛋白質 / Glycolipid / Defensive Substance / Antitumor Compound / DNA Cleavage Mechanism / Carcinogenic Substance / Marine Natural Product / Terpenoid Dialdehyde / 膜透過 / 抗酸化性天然物質 / 抗腫瘍性天然物質 / DNA切断分子機構 / ワラビ発癌物質 / 神経興奮性物質 / 海洋天然物質 / 複合糖質 / DNA切断機構 / 抗腫瘍性物質 / 発癌物質 / 捕食防御物質 / シガテラ毒 / 海産天然物 / テルペノイドジアルデヒド / Allelopasic substances / Antifeedant / Cell decision inhibitors / Carcinogenic promotors / Cell grouth control factors / Neurotrophic compounds / Isolation of neurotoxins / Neurotoxins / 発癌性物質 / 発癌プロモ-タ- / 神経毒の合成 / 他感作用物質 / 摂食阻害物質 / 卵割阻害活性物質 / 発癌プロモーター / 細胞生長制御物質 / 神経突起伸展作用物質 / 神経毒の単離 / 神経毒 / 未解明生物現象 / 構造決定方法論 / 天然新分子 / 企画調査 / 特定領域研究 / 天然物化学 / 蛋白質 / 糖質 / 脂質 / DNA / 構造認識 / 精密構造認識 / アレロケミックス / 水圏生態系 / 海洋天然物化学 Less

Elucidation of structural principal in active state of membrane proteins using fused polycyclic ethersPrincipal Investigator
- Principal Investigator
  
  TACHIBANA Kazuo
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Living organism molecular science
- Research Institution
  The University of Tokyo
Molecular Mechanism of Action for Particularly Potent Marine Biotoxins.
- Principal Investigator
  
  MURATA Michio
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Osaka University
  The University of Tokyo
Practical Configuration Analysis for Natural Products.
- Principal Investigator
  
  MURATA Michio
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  分離・精製・検出法
- Research Institution
  Osaka University
  The University of Tokyo
新分子の発見と21世紀の天然物化学
- Principal Investigator
  
  平間正博
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Tohoku University
Membrane Protein Recognition by Ladder-shaped Polyether Compounds
- Principal Investigator
  
  MURATA Michio
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  The University of Tokyo
脂質の関与する超分子形成と機能Principal Investigator
- Principal Investigator
  
  橘和夫
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
天然超分子化学の総合的研究
- Principal Investigator
  
  楠本正一
- Project Period (FY)
  1994 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
超活性海洋天然物の有機化学
- Principal Investigator
  
  安元健
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Tohoku University
天然超分子の化学的研究
- Principal Investigator
  
  KUSUMOTO Syouichi
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Institution
  Osaka University
COMPREHENSIVE RESEARCH TOWARD THE ELUCIDATION OF BIOLOGICAL ACTIVITIES OF NATURAL ORGANIC COMPOUNDS
- Principal Investigator
  
  ISOE Sachihiko
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  OSAKA CITY UNIVERSITY
超活性海洋天然物の化学Principal Investigator
- Principal Investigator
  
  橘和夫
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  天然物有機化学
- Research Institution
  The University of Tokyo
ORGANIC CHEMISTRY OF THE BIOSYSTEM CONTROL SUBSTANCES
- Principal Investigator
  
  SHIRAHAMA Haruhisa
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  天然物有機化学
- Research Institution
  HOKKAIDO UNIVERSITY,(FACULTY OF SCIENCE)

All 2007 2006 2005

All Journal Article Book

[Book] 18. 巻頭言 : 合成標的化合物の選択. 65, 800.2007
- Author(s)
  橘和夫
- Total Pages
  1
- Publisher
  有機合成化学協会
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16201044
[Book] 私が化学者になった理由 : 自然の不思議を解明する化学にであう2005
- Author(s)
  橘和夫
- Total Pages
  1
- Publisher
  化学同人
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16201044
[Journal Article] Thermal analyses of phospholipid mixtures by differential scanning calorimetry and effect of doping with a bolaform amphiphile.2007
- Author(s)
  Sasaki, R., Sasaki, H., Fukuzawa, S., Kikuchi, J., Hirota, H., Tachibana, K.
- Journal Title
  
  Bull Chem. Soc. Jpn. 80
  
  Pages: 1208-1216
- NAID
  10019586827
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201044
[Journal Article] Design and synthesis of simplified polycyclic ethers and evaluation of their interaction with α-helical peptide as a model of target proteins.2007
- Author(s)
  M. Sasaki, K. Tachibana
- Journal Title
  
  Tetrahedron Lett. 48
  
  Pages: 3181-3186
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16201044
[Journal Article] Design and synthesis of simplified polyctclic ethers and evaluation of their interaction with α-helical peptide as a model of target proteins.2007
- Author(s)
  M. Sasaki, K. Tachibana
- Journal Title
  
  Tetrahedron Lett. 48
  
  Pages: 3181-3186
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201044
[Journal Article] Isolation and Characterization of Okadaic Acid Binding Proteins from the Marine Sponge Halichondria okadai.2007
- Author(s)
  Sugiyama, N., Konoki, K., Tachibana, K.
- Journal Title
  
  Biochemistry 46
  
  Pages: 11410-11420
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201044
[Journal Article] Design and synthesis of simplified polyctclic ethers and evaluation of their interaction with α-helical peptide as a model of target proteins.2007
- Author(s)
  M. Sasaki and K. Tachibana
- Journal Title
  
  Tetrahedron Lett. 48
  
  Pages: 3181-3186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16201044
[Journal Article] Site-specific Functionalization of Proteins by Organopalladium Reactions.2007
- Author(s)
  Kodama, K., Fukuzawa, S., Nakayama, H., Kigawa. T., Sakamoto, K., Yabuki, T., Matsuda, N., Shirouzu, M., Takio, K., Yokoyama, S., Tachibana, K.
- Journal Title
  
  ChemBioChem 8
  
  Pages: 232-238
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201044
[Journal Article] Regioselective Carbon-Carbon Bond Formation in Proteins by Palladium-catalysis; New Protein Chemistry by Organometallic Chemistry.2006
- Author(s)
  Kodama, K., Fukuzawa, S., Nakayama. H., Kigawa, T., Sakamoto, K., Yabuki, T., Matsuda, N., Shirouzu, M., Takio, K., Tachibana, K., Yokoyama, S.
- Journal Title
  
  ChemBioChem 7
  
  Pages: 134-139
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201044
[Journal Article] A comparative study of the fragmentation of neutral lactooligosaccharides in negative-ion mode by UV-MALDI-TOF and UV-MALDI Ion-trap/TOF mass spectrometry.2006
- Author(s)
  T.Yamagaki, H.Suzuki, K.Tachibana
- Journal Title
  
  Journal of American Society of Mass Spectrometry. 77・6
  
  Pages: 67-74
- Data Source
  KAKENHI-PROJECT-16201044
[Journal Article] Analysis of glycosyl bond cleavage and related isotope effects in collision-induced dissociation qaudrupole-time-of-flight mass spectrometry of isomeric treharoses2006
- Author(s)
  T.Yamagaki, K.Fukui, K.Tachibana
- Journal Title
  
  Analytical Chemistry. 78・4
  
  Pages: 1015-1022
- Data Source
  KAKENHI-PROJECT-16201044
[Journal Article] Regioselective Carbon-Carbon Bond Formation in Proteins by Palladium-catalysis ; New Protein Chemistry by Organometallic Chemistry.2006
- Author(s)
  K.Kodama, S.Fukuzawa, H.Nakayama, T.Kigawa, K.Sakamoto, T.Yabuki, M.Matsuda, M.Shirouzu, K.Takio, K.Tachibana, S.Yokoyama
- Journal Title
  
  ChemBioChem 7・1
  
  Pages: 134-139
- Data Source
  KAKENHI-PROJECT-16201044
[Journal Article] A New Protein Engineering Approach Combining Chemistry and Biology, Part I; Site-specific Incorporation of 4-iodo-L-phenylalanine in vitro Using Mis-acylated Suppressor tRNA ^<phe>.2006
- Author(s)
  Kodama, K., Fukuzawa, S., Nakayama, H., Kigawa, T., Sakamoto, K., Yabuki, T., Matsuda, N., Shirouzu, M., Takio, K., Tachibana, K., Yokoyama, S.
- Journal Title
  
  ChemBioChem 7
  
  Pages: 1577-1581
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201044
[Journal Article] In-sourse and postsouce decay in negative-ion matrix-assisted laser desorption/ionization time-of-flight mass spectometry of neutra2005
- Author(s)
  T.Yamagaki, H.Suzuki, K.Tachibana
- Journal Title
  
  Analytical Chemistry 77・6
  
  Pages: 1701-1707
- Data Source
  KAKENHI-PROJECT-16201044
[Journal Article] In-source and postsource decay in negative-ion MALDI-TOF mass spectrometry of neutral oligosaccharides.2005
- Author(s)
  T.Yamagaki, H.Suzuki, K.Tachibana
- Journal Title
  
  Analytical Chemistry 77・6
  
  Pages: 1701-1707
- Data Source
  KAKENHI-PROJECT-16201044
[Journal Article] On-probe sample preparation without washes for matrix assisted laser desorption ionization mass spectrometry based on a combination of electrostatic interactions and a molecular sieve effects.2005
- Author(s)
  S.Fukuzawa, H.Asanuma, K.Tachibana, H.Hirota
- Journal Title
  
  Analytical Chemistry 77・17
  
  Pages: 5750-5754
- Data Source
  KAKENHI-PROJECT-16201044
[Journal Article] Dynamic NMR study in the trans-fused eight-membered ether ring model representing G ring of brevetoxin A2005
- Author(s)
  T.Shida, K.Tachibana
- Journal Title
  
  Tetrahedron Letters 46・11
  
  Pages: 1855-1857
- Data Source
  KAKENHI-PROJECT-16201044
[Journal Article] Optimization of matrix and amount of ammonium chloride additive for effective ionization of neutral oligosaccharides as chlorinated molecular ions in negative-ion MALDI-TOF MS.2005
- Author(s)
  H.Suzuki, T.Yamagaki, K.Tachibana
- Journal Title
  
  Journal of Mass Spectrometry Society of Japan. 53・4
  
  Pages: 227-229
- Data Source
  KAKENHI-PROJECT-16201044

1. HIRAMA Masahiro (30165203)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. YAMADA Kiyoyuki (90022540)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. KUSUMOTO Syouichi (30028253)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. MURATA Michio (40183652)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. ISOBE Minoru (00023466)

# of Collaborated Projects: 3 results

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6. 安元健 (20011885)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. SHIRAHAMA Haruhisa (00000802)

# of Collaborated Projects: 2 results

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8. YAMAMURA Syosuke (40076708)

# of Collaborated Projects: 2 results

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9. SASAKI Makoto (80235267)

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10. 北川勲 (20028830)

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11. 中村英士 (90217878)

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12. 楠見武徳 (70015882)

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13. 小倉協三 (80006303)

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14. 三川潮 (60012613)

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15. 杉浦幸雄 (40025698)

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16. 上村大輔 (00022731)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. ISOE Sachihiko (90046946)

# of Collaborated Projects: 1 results

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18. MURAI Akio (20000838)

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19. KONOKI Keiichi (40292825)

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20. MATSUMORI Nobuaki (50314357)

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21. FUKUZAWA Seketsu (40321806)

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# of Collaborated Products: 6 results
22. 佐竹真幸 (90261495)

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23. 佐藤清隆 (80034479)

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24. 岡畑恵雄 (80038017)

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25. 柴崎正勝 (30112767)

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26. 越智雅光 (40036562)

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27. 中山充 (20033821)

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28. 菅隆幸 (00033811)

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29. 林雄二 (40046917)

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30. 野老山喬 (90046938)

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31. 児玉三明 (30004378)

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32. 上江田捷博 (10145550)

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33. 奥村保明 (20021933)

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34. 加藤忠弘 (20004319)

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35. 加藤紀元 (00006305)

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36. UTSUMI Hiroaki

# of Collaborated Projects: 1 results

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TACHIBANA Kazuo 橘 和夫

Research Projects

Research Products

Co-Researchers

Elucidation of structural principal in active state of membrane proteins using fused polycyclic ethersPrincipal Investigator

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脂質の関与する超分子形成と機能Principal Investigator

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超活性海洋天然物の化学Principal Investigator

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[Book] 18. 巻頭言 : 合成標的化合物の選択. 65, 800.2007

Author(s)

Total Pages

Publisher

Description

Data Source

[Book] 私が化学者になった理由 : 自然の不思議を解明する化学にであう2005

Author(s)

Total Pages

Publisher

Description

Data Source

[Journal Article] Thermal analyses of phospholipid mixtures by differential scanning calorimetry and effect of doping with a bolaform amphiphile.2007

Author(s)

Journal Title

NAID

TACHIBANA Kazuo 橘和夫