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OKAMURA Tomio  岡村 富夫

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… Alternative Names

岡村 富夫  オカムラ トミオ

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Researcher Number 70152337
Other IDs
External Links
Affiliation (Current) 2025: 滋賀医科大学, 医学部, 非常勤講師
Affiliation (based on the past Project Information) *help 2011 – 2013: 滋賀医科大学, 医学部, 教授
2005 – 2006: 滋賀医科大学, 医学部, 教授
1999 – 2001: Shiga University of Medical Science, Phamacology, Professor, 医学部, 教授
1996 – 1998: 滋賀医科大学, 医学部, 助教授
1989 – 1992: 滋賀医科大学, 医学部, 助教授
1990: Shiga University of Medical Science, Department of Pharmacology, Assistant Profe, 医学部, 助教授
Review Section/Research Field
Principal Investigator
General pharmacology / 応用薬理学・医療系薬学 / General pharmacology
Except Principal Investigator
General pharmacology / General pharmacology / 応用薬理学・医療系薬学 / Anesthesiology/Resuscitation studies
Keywords
Principal Investigator
NO作動性神経 / 一酸化窒素 / 脳動脈 / EDRF / カルシウム拮抗薬 / 陰茎海綿体 / Hypothermia / corpus cavernosum / Superoxide / Cerebral and ophthalmic artery … More / Vasodilator nerve / Pterygopalatine ganglion / Nitroxidergic (Nitrergic) nerve / Nitric Oxide (NO) / 血管造影 / 神経伝達物質 / 眼動脈 / 低酸素 / Caged NO / 低温 / スーパーオキシド / 脳および眼動脈 / 血管拡張神経 / 翼口蓋神経節 / Noradrenaline / calmodulin-dependent protein kinase / Calcium / Cyclic GMP / Flunarizine / Nitroxidergic nerve / Nitric oxide / Calcium antagonist / 血管平滑筋 / 血管緊張性調節 / 血管内皮由来弛緩因子(EDRF) / 一酸化窒素(NO) / ノルアドレナリン / サイクリックGMP / カルシウム・カルモデュリン依存性プロテインキナーゼII / フルナリジン / Human artery / Renin inhibitor / Vascular endothelium / Immunohistochemistry / Renin antibody / Angiotensin-converting enzyme / Angiotensin / Renin / 腎摘ラット / 血管壁 / ヒト血管 / レニン阻害薬 / 瞳孔括約筋 / 血管内皮 / 免疫組織化学 / レニン抗体 / アンジオテンシン変換酵素 / アンジオテンシン / レニン / 血管内皮機能 / 神経型NO合成酵素 / 血管内皮細胞 / 末梢神経 / 活性酸素 / 生活習慣病 / 平滑筋支配神経 / NO作動性神経 … More
Except Principal Investigator
一酸化窒素(NO) / 陰茎海綿体 / corpus cavernosum / nitric oxide (NO) / endothelium / Ca^<2+>感受性K^+チャネル / 内皮細胞 / 一酸化窒素 / NO作動性神経 / 血管内皮 / 脳動脈 / サル / Tetrahydrobiopterin / Nitric oxide synthase / Oxidative stress / Angiotensin / Hyperlipidemia / Endothelial dysfunction / Insulin resistance / HMG-CoA還元酵素阻害薬 / フィブラート / 血管内皮機能障害 / テトラヒドロビオプテリン / テトラヒドロピオプテリ / 一酸化窒素合成酵素 / 酸化ストレス / アンジオテンシン / 高脂血症 / 内皮機能障害 / インスリン抵抗性 / atherosclerosis / hyperlipidemic rabbit and monkey / cytochrome P450 3A4 / Ca^<2+>-dependent K^+-channel / lingual, carotid and cerebral arteries / 血管支配神経 / 動脈硬化モデル動物 / Ca2+依存性K+チャネル / 動脈硬化 / 高脂血症ウサギおよびサル / チトクロームP450 3A4 / Ca2+依存症K+チャネル / 舌,頚および脳動脈 / biocascade system / nitroxidergic nerve / metabolite(s) from arachidonic acid / endotherium-derived hyperpolarization factor (EDHF) / coronary of linguial artery / サル舌動脈 / アラキドン酸 / チトクロームP450 / バイオカスケード装置 / アラキドン酸代謝物 / 内皮由来過分極因子(EDHF) / 冠状および舌動脈 / Blood pressure / Vasodilator nerve / Prejunctional inhibition / Reciprocal innervation / Corpus cavernosum / Cerebral artery / Nitroxidergic nerve / Nitric Oxide (NO) / 高血圧 / 網膜中心動脈 / 舌動脈 / 蛋白リン酸化 / コリン作動性神経 / ascorbic acid / calcium entry blocker, / cyclooxygenase inhibitor, / endothelium, / prostaglandin, / oxyhemoglobin, / subarachnoid hemorrhage, / Cerebral vasospasm, / 大脳動脈 / 赤血球溶血上清液 / 内皮依存性収縮 / プロスタグランディン / 脳血管攣縮 / クモ膜下出血 / オキシヘモグロビン / 血管弛緩 / T細胞 / オピオイド受容体 / 血管平滑筋 / 免疫抑制 / オピオイド / Tリンパ球 / モルヒネ / 麻薬 / カニクイザル / 幹細胞移植 / 再生医療 / iPS細胞 / 幹細胞機能 / 糖尿病 / インスリン抵抗性因子 / 幹細胞 Less
  • Research Projects

    (11 results)
  • Research Products

    (24 results)
  • Co-Researchers

    (11 People)
  •  Nitrergic function in life style-related diseasesPrincipal Investigator

    • Principal Investigator
      OKAMURA Tomio
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Shiga University of Medical Science
  •  Effects of insulin resistance-related factors on the stem cell functions in vivo.

    • Principal Investigator
      IMAMURA Takeshi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Shiga University of Medical Science
  •  The study on functions of opioid receptors expressed in T lymphocytes

    • Principal Investigator
      SHODA Takehiro
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Kyoto University
  •  Role of PPARα in Pathogenesis of Endothelial Dysfunction Associated with Insulin Resistance

    • Principal Investigator
      SHINOZAKI Kazuya
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Shiga University of Medical Science
  •  Function of vascular endothelium and vasomotor nerve in atherosclerotic animals

    • Principal Investigator
      AYAJIKI Kazuhide
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Shiga University of Medical Science
  •  Analyses of projection route of nitroxidergic nerve and its transmission mechanismPrincipal Investigator

    • Principal Investigator
      OKAMURA Tomio
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Shiga University of Medical Science
  •  Measurement of vasorelaxant substance derived from endothelium and innervating nerve by biocascade system

    • Principal Investigator
      AYAJIKI Kazuhide
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Shiga University of Medical Science
  •  Analysis of Mechanisms Underlying Vascular Nitroxidergic Innervation and its Pathogenic Implication

    • Principal Investigator
      TODA Noboru
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Shiga University of Medical Science
  •  Effects of calcium antagonists on vascular endothelial, smooth muscle and sympathetic nerve functionsPrincipal Investigator

    • Principal Investigator
      OKAMURA Tomio
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      SHIGA UNIVERSITY OF MEDICAL SCIENCE
  •  Basic Research on the vascular renin-angiotensin systemPrincipal Investigator

    • Principal Investigator
      OKAMURA Tomio
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      SHIGA UNIVERSITY OF MEDICAL SCIENCE
  •  Basic Research on Cerebral Vasospasm and Its Prophylaxis

    • Principal Investigator
      TODA Noboru
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Shiga University of Medical Science

All 2014 2013 2012 2011

All Journal Article Presentation

  • [Journal Article] Effects of atorvastatin, amlodipine, and their combination on vascular dysfunction in insulin-resistant rats2014

    • Author(s)
      Okamura T, Tawa M, Geddawy A, Shimosato T, Iwasaki H, Shintaku H, Yoshida Y, Masada M, Shinozaki K, Imamura T
    • Journal Title

      J Pharmacol Sci

      Volume: 124 Pages: 76-85

    • NAID

      130003382630

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390055
  • [Journal Article] Effects of atorvastatin, amlodipine, and their combination on vascular dysfunction in insulin-resistant rats.2014

    • Author(s)
      Okamura T, Tawa M, Geddawy A, Shimosato T, Iwasaki H, Shintaku H, Yoshida Y, Masada M, Shinozaki K, Imamura T.
    • Journal Title

      J Pharmacol Sci.

      Volume: 124 Pages: 76-85

    • NAID

      130003382630

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390056
  • [Journal Article] Effects of atorvastatin, amlodipine, and their combination on vascular dysfunction in insulin-resistant rats.2014

    • Author(s)
      Okamura T, Tawa M, Geddawy A, Shimosato T, Iwasaki H, Shintaku H, Yoshida Y, Masada M, Shinozaki K, Imamura T.
    • Journal Title

      J Pharmacol Sci

      Volume: 124 Pages: 76-85

    • NAID

      130003382630

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390055
  • [Journal Article] Effects of atorvastatin, amlodipine, and their combination on vascular dysfunction in insulin-resistant rats2014

    • Author(s)
      Okamura T, Tawa M, Geddawy A, Shimosato T, Iwasaki H, Shintaku H, Yoshida Y, Masada M, Shinozaki K, Imamura T
    • Journal Title

      J Pharmacol Sci

      Volume: 124 Pages: 76-85

    • NAID

      130003382630

    • URL

      https://www.jstage.jst.go.jp/article/jphs/124/1/124_13178FP/_article

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390056
  • [Journal Article] Obesity impairs vasodilatation and blood flow increase mediated by endothelial nitric oxide : An overview2013

    • Author(s)
      Toda N, Okamura T
    • Journal Title

      J Clin Pharmacol

      Volume: 53 Pages: 1228-1239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390055
  • [Journal Article] Influence of hypoxia on endothelium-derived NO-mediated relaxation in rat carotid, mesenteric and iliac arteries2013

    • Author(s)
      Tawa M, Shimosato T, Geddawy A, Imamura T, Okamura T
    • Journal Title

      Pharmacology

      Volume: 91 Pages: 322-330

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390055
  • [Journal Article] Obesity impairs vasodilatation and blood flow increase mediated by endothelial nitric oxide: An overview.2013

    • Author(s)
      Toda N, Okamura T.
    • Journal Title

      J Clin Pharmacol.

      Volume: 53 Issue: 12 Pages: 1228-1239

    • DOI

      10.1002/jcph.179

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390055
  • [Journal Article] Regulation of myometrial circulation and uterine vascular tone by constitutive nitric oxide.2013

    • Author(s)
      Toda N, Toda H, Okamura T.
    • Journal Title

      Eur J Pharmacol.

      Volume: 714 Issue: 1-3 Pages: 414-423

    • DOI

      10.1016/j.ejphar.2013.07.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390055
  • [Journal Article] Hypoxia on Endothelium-Derived NO-Mediated Relaxation in Rat Carotid, Mesenteric and Iliac Arteries.2013

    • Author(s)
      Tawa M, Shimosato T, Geddawy A, Imamura T, Okamura T.
    • Journal Title

      Pharmacology

      Volume: 91 Issue: 5-6 Pages: 332-330

    • DOI

      10.1159/000351706

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390055, KAKENHI-PROJECT-23390056
  • [Journal Article] Regulation of myometrial circulation and uterine vascular tone by constitutive nitric oxide2013

    • Author(s)
      Toda N, Toda H, Okamura T
    • Journal Title

      Eur J Pharmacol

      Volume: 714 Pages: 414-423

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390055
  • [Journal Article] Neurogenic and endothelial nitric oxide regulates blood circulation in lingual and other oral tissues2012

    • Author(s)
      Toda, Ayajiki, Okamura
    • Journal Title

      J Cardiovasc Pharmacol

      Volume: 60 Issue: 1 Pages: 100-108

    • DOI

      10.1097/fjc.0b013e318252452a

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390055
  • [Journal Article] Chronic Administration of Nicotine-Free Cigarette Smoke Extract Impaired Endothelium-Dependent Vascular Relaxation in Rats via Increased Vascular Oxidative Stress2012

    • Author(s)
      Shimosato, Geddawy, Tawa, Imamura, Okamura
    • Journal Title

      J Pharmacol Sci

      Volume: 118 Issue: 2 Pages: 206-214

    • DOI

      10.1254/jphs.11187FP

    • NAID

      10030454848

    • ISSN
      1347-8613, 1347-8648
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390055
  • [Journal Article] Cerebral blood flow regulation by nitric oxide in Alzheimer's disease.2012

    • Author(s)
      Toda, Okamura
    • Journal Title

      J Alzheimers Dis.

      Volume: 32 Issue: 3 Pages: 569-578

    • DOI

      10.3233/jad-2012-120670

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390055
  • [Journal Article] Chronic Administration of Nicotine-Free Cigarette Smoke Extract Impaired Endothelium-Dependent Vascular Relaxation in Rats via Increased Vascular Oxidative Stress2012

    • Author(s)
      Shimosato T, Geddawy A, Tawa M, Imamura T, Okamura T
    • Journal Title

      J Pharmacol Sci

      Volume: 118 Pages: 206-214

    • NAID

      10030454848

    • URL

      https://www.jstage.jst.go.jp/article/jphs/118/2/118_11187FP/_article

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390056
  • [Journal Article] Cerebral blood flow regulation by nitric oxide in Alzheimer's disease2012

    • Author(s)
      Toda N, Okamura T
    • Journal Title

      J Alzheimers Dis

      Volume: 32 Pages: 569-578

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390055
  • [Journal Article] Chronic administration of micotine-free cigarette smoke extract impaired endothelium-dependent vascular relaxation in rats via increased vascular oxidative stress2012

    • Author(s)
      Shimosato T, Geddawy A, Tawa M, Imamura T, Okamura T
    • Journal Title

      J Pharmacol Sci

      Volume: 118 Pages: 206-214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390055
  • [Journal Article] Neurogenic and endothelial nitric oxide regulates blood circulation in lingual and other oral tissues2012

    • Author(s)
      Toda N, Ayajiki K, Okamura T
    • Journal Title

      J Cardiovasc Pharmacol

      Volume: 60 Pages: 100-108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390055
  • [Journal Article] Neurogenic and endothelial nitric oxide regulates blood circulation in lingual and other oral tissues2012

    • Author(s)
      Toda, Ayajiki, Okamura
    • Journal Title

      J Cardiovasc Pharmacol

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390055
  • [Journal Article] Nitrergic nerves derived from the pterygopalatine ganglion innervate arteries irrigating the cerebrum but not the cerebellum and brain stem in monkeys2012

    • Author(s)
      Ayajiki K, Kobuchi S, Tawa M, Okamura T
    • Journal Title

      Hypertens Res

      Volume: 35 Pages: 88-92

    • NAID

      10030643093

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390055
  • [Journal Article] Impairment by hypoxia or hypoxia/reoxygenation of nitric oxide-mediated relaxation in isolated monkey coronary artery : the role of intracellular superoxide2011

    • Author(s)
      Tawa M, Yamamizu K, Geddawy A, Shimosato T, Imamura T, Ayajiki K, Okamura T
    • Journal Title

      J Pharmacol Sci

      Volume: 116 Pages: 188-196

    • NAID

      10029894695

    • URL

      https://www.jstage.jst.go.jp/article/jphs/116/2/116_11031FP/_article

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390056
  • [Journal Article] Contribution of nitric oxide in big endothelin-1-induced cardioprotective effects on ischemia/ reperfusion injury in rat hearts2011

    • Author(s)
      Tawa M, Fukumoto T, Ohkita M, Yamashita N, Geddawy A, Imamura T, Ayajiki K, Okamura T, Matsumura Y
    • Journal Title

      J Cardiovasc Pharmacol

      Volume: 57 Issue: 5 Pages: 575-578

    • DOI

      10.1097/fjc.0b013e31821325ad

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390056
  • [Presentation] GSK3beta differentially modifies early and late stages of adipogenesis from the pluripotent stem cells to mature adipocytes2014

    • Author(s)
      今村武史、岩崎広高、田和正志、下里 貴、岡村富夫
    • Organizer
      日本薬理学会
    • Place of Presentation
      徳島大学
    • Data Source
      KAKENHI-PROJECT-23390056
  • [Presentation] Effects of insulin resistance on adipogenic differentiation of the stem cells transplanted in cynomolgus monkeys.2013

    • Author(s)
      今村武史、岩崎広高、田和正志、下里 貴、岡村富夫
    • Organizer
      日本薬理学会
    • Place of Presentation
      福岡国際センター
    • Data Source
      KAKENHI-PROJECT-23390056
  • [Presentation] インスリン抵抗性ラットにおける血管機能障害に及ぼすアトロバスタチンおよびアムロジピンの併用効果2013

    • Author(s)
      田和正志, 下里貴, Geddawy Ayman, 新宅治夫, 政田正広, 今村武史, 岡村富夫
    • Organizer
      第13回日本NO学会
    • Place of Presentation
      沖縄県医師会館
    • Data Source
      KAKENHI-PROJECT-23390055
  • 1.  AYAJIKI Kazuhide (10167968)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 2.  IMAMURA Takeshi (00552093)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 13 results
  • 3.  TAWA Masashi (10510274)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 14 results
  • 4.  TODA Noboru (50025590)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  YOSHIDA Kazuhide (00210683)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  FUJIOKA Hideyuki (50228970)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  MASADA Masahiro (00229353)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 8.  TORII Ryuzou (50106647)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  YOSHIDA Yoshinori (20447965)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 10.  SHODA Takehiro (60335263)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  SHINOZAKI Kazuya (20324577)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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