WAKABAYASHI Shigeo 若林繁夫

Researcher Number	70158583
Other IDs
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Affiliation (based on the past Project Information) *help	2016 – 2019: 大阪医科大学, 医学部, 非常勤講師 2017: 大阪医科大学, 生命科学講座薬理学, 非常勤講師 2016: 大阪医科大学, 医学研究科・薬理学教室, 研究員 2015: 国立研究開発法人国立循環器病研究センター, 研究所, 非常勤研究員 2014: 独立行政法人国立循環器病研究センター, 研究所, 非常勤研究員 … More 2012 – 2013: 独立行政法人国立循環器病研究センター, 研究所, 部長 2010 – 2011: National Cardiovascular Center Research Institute, 分子生理部, 部長 2009: National Cardiovascular Center Research Institute, 循環分子生理部, 部長 2006 – 2009: 国立循環器病センター研究所, 循環分子生理部, 部長 2008: National Cardiovascular Center Research Institute, 循環分子生理部, 部長 2007: National Cardiovascular Center Research Institute, 研究所・循環分子生理部, 部長 2004 – 2006: 国立循環器病センター(研究所), 循環分子生理部, 部長 2003: National Cardiovascular Center Research Institute, Dept.of Molecular Physiology, Director, 循環分子生理部, 部長 1998 – 2002: Dept.Mol.Physiol.NCVC, 循環分子生理部, 室長 1995 – 1997: 国立循環器病センター研究所, バイオサイエンス部, 室長 1995: 同研究所, バイオサイエンス部, 室長 1994: 国立循環器病センター研究所, バイオサイエンス部, 研究室長 1992 – 1993: 国立循環器病センター研究所, バイオサイエンス部, 室長 1987: National Cardiovascular Center, 病因部, 室員 1987: 国立循環器病センター研究所, 病因部, 研究員 1986: 国立循環器病センター, 研究所病因部, 室員 Less
Review Section/Research Field	Principal Investigator Functional biochemistry / General physiology / Biological Sciences / Circulatory organs internal medicine / General medical chemistry / 代謝生物化学 Except Principal Investigator General physiology / General physiology / Biological Sciences / Biological pharmacy / Circulatory organs internal medicine
Keywords	Principal Investigator Na^+ / 細胞内pH / 生体分子 / カルモデュリン / 増殖因子 / 蛋白質 / バイオテクノロジー / Na+ / 細胞内Ca^<2+> / 循環器・高血圧 … More / シグナル伝達 / H^+交換輸送体 / タンパク質 / 結晶構造 / H^+ exchanger / タンパク質リン酸化 / トランスレーショナルリサーチ / 生理学 / 細胞内シグナル伝達 / トランスポータ / Na+/H+交換輸送体 / calmodulin / 細胞容積調節 / 細胞容積 / カルシニューリン類似タンパク質 / H^+アンチポータ / 生物・生体工学 / 生物物理 / ナノマシン / Intracellular pH / Biophysics / Protein / 阻害ドメイン / キメラタンパク質 / H^+ exchanger (NHE) / プロテインキナーゼ / ドメイン構造 / プロテオーム / 生体膜 / チャネル / トランスポーク / 受容体 / 生理活性脂質 / 創薬 / 細胞内イオン制御 / トランスポーター / 心筋リモデリング / Ca2+結合蛋白質 / 心肥大 / 低酸素刺激 / ノックアウトマウス / イオン輸送体 / 遺伝子改変マウス / 心不全 / カテコールアミン / ベータリセプター / H^+ exchanger(NHE1) / 浸透圧 / H^+交換輸送系 / 細胞増殖因子 / 浸透圧刺激 / 部位特異的変異導入 / 細胞内制御因子 / H+ exchanger (NHE1) / intracellular pH / Intracellular Ca2+ / growth factor / osmotic stress / H+交換輸送体 / カルシニュウリン類似タンパク質 / Ca^<2+>交換輸送体 / プロテインキナーゼC / 細胞内PH / 情報伝達 / H+ exchanger / volume regulation / calcineurin homologue protein / 膜トポロジー / 変異導入 / CHP / Li^+イオン / membrane topology / mutagevesis / Volume regulation / Calcineurin-homologous protein / lithium ion / H+ antiporter / Crystal structure / Biochemistry / nanomachine / Biological Molecule / H+アンチポータ / H^+ antiporter / Protein Crystal structure / Bioengineering / Nano-machine / Bio-molecule / iPS細胞 / NHE1 / rhoキナーゼ / 細胞死 / 細胞運動 / ネクロ―シス / Rhoキナーゼ / モネンシン / 心筋細胞分化 / ゲノム編集 / 心筋収縮 / 遺伝子発現 … More Except Principal Investigator Na^+ / H^+交換輸送系 / Ca^<2+>交換輸送系 / カチオン交換輸送系 / 心肥大 / カルシウムセンサー / H^+ exchanger / Ca^<2+>交換輸送体 / Ca^<2+> exchanger / カルシウム / Na / Ca交換体阻害薬 / Isothiourea誘導体 / ニッケルイオン / カルシウムシグナリング / プロティンキナーゼC / 阻害薬 / 神経科学 / 生理学 / 神経生理学 / セルセンサー / モーダルシフト / 脳・神経 / 細胞生理学 / 心機能 / カルシウムシグナル / サバイバル / シグナル伝達 / 心筋収縮 / 心疾患 / トランスポーター / カルシニューリン / ｐH / イオン輸送体 / 細胞内ｐH / NFAT / 筋小胞体 / Ca^<2+>ポンプ / Ca^<2+>ATPase / Cation exchanger / Ca^<2+>交換阻害薬 / Ca^<2+>シグナリング / H^+交換輸送体 / Ca^<2+> exchange inhibitor / Ca^<2+> signaling / 心筋Na^+ / H^+交換系 / 心筋Naポンペ / 心筋小胞体Caポンプ / 心筋形質膜 / 【Na^+】 / 【Ca^(2+)】交換系 / 【H^+】交換系 / 再構成膜小胞 / Na pump / 細胞生物学 / 分子生物学 / 心筋細胞 / 興奮収縮連関 / 受容体刺激 / 細胞内シグナル伝達 / イノシトール三リン酸受容体 / heart failure / hypertrophy / hypoxia / Ca2+-binding protein / 肺高血圧 / Ca2+結合蛋白質 / 低酸素負荷 / CHP3欠損マウス / 心不全 / ＮＨＥ１ / Ca2+シグナル / ベータ遮断薬 / CHP3 / 代謝異常 / ミトコンドリア / 肥満 / 代謝疾患 / メタボローム解析 / 肥満制御 / カルシムシグナル / ミトコンドリア呼吸 / 代謝 Less

Analysis of novel genes involved in cardiac function using iPSC-derived cardiomyocytesPrincipal Investigator
- Principal Investigator
  
  Wakabayashi Shigeo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Osaka Medical College
Study on the drug exercise therapy that is effective for cardiac hypertrophy heart failure that develops in Ca2 + load model mouse
- Principal Investigator
  
  JIN MEIHUA
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  National Cardiovascular Center Research Institute
Novel mechanism for energy metabolism regulated by a Ca2+-sensor protein
- Principal Investigator
  
  Nishitani Tomoe
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  National Cardiovascular Center Research Institute
Amplification of intracellular signaling initiated near the plasma membrane transportersPrincipal Investigator
- Principal Investigator
  
  Wakabayashi Shigeo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Osaka Medical College
  National Cardiovascular Center Research Institute
A role of neuronal calcium sensor-1 on the nuclear calcium regulation in cardiomyocytes: contribution to cardiac hypertrophy
- Principal Investigator
  
  NAKAO Shu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  National Cardiovascular Center Research Institute
Molecular mechanism for regulaiton of ion transporter via lipid signaling and its structural basisPrincipal Investigator
- Principal Investigator
  
  WAKABAYASHI Shigeo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  National Cardiovascular Center Research Institute
Role of a pH-regulating transporter NHE1 as a novel activator of calcineurin
- Principal Investigator
  
  HISAMITSU Takashi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Cardiovascular Center Research Institute
Molecular mechanism for regulation of ion transporter and channel by bioactive I ipidsPrincipal Investigator
- Principal Investigator
  
  WAKABAYAHSI Shigeo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  National Cardiovascular Center Research Institute
Pathological roles of ion transporter/channel as therapeutic targets in muscle degenerative diseasePrincipal Investigator
- Principal Investigator
  
  WAKABAYASHI Shigeo
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  National Cardiovascular Center Research Institute
Physiological role of NCS-1, a Ca^<2+> sensor, in the heart
- Principal Investigator
  
  NISHITANI Tomoe
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  National Cardiovascular Center Research Institute
Na+/H+アンチポータの機能制御複合体を構成する新規タンパク質の探索Principal Investigator
- Principal Investigator
  
  若林繁夫
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Cardiovascular Center Research Institute
Molecular interaction and modal shift for cell sensors
- Principal Investigator
  
  TOMINAGA Makoto
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institutes of Natural Sciences Okazaki Research Facilities
Regulatory mechanism for interaction between membrane proton sensor and cytosolic ion sensor.Principal Investigator
- Principal Investigator
  
  WAKABAYASHI Shigeo
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Cardiovascular Center Research Institute
ストレッチ感受性Ca^<2+>チャネルを標的にした筋変性疾患治療薬物の開発Principal Investigator
- Principal Investigator
  
  若林繁夫
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  National Cardiovascular Center Research Institute
The Na+/H+ exchanger as a proton regulatory system : its molecular structure and transport mechanismPrincipal Investigator
- Principal Investigator
  
  WAKABAYASHI Shigeo
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  National Cardiovascular Center Research Institute
Structure, function and regulation of the mammalian Na+/H+ antiportersPrincipal Investigator
- Principal Investigator
  
  WAKABAYASHI Shigeo
- Project Period (FY)
  2001 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Cardiovascular Center Research Institute
Structure, function and regulation of the Na^+/H^+ exchangerPrincipal Investigator
- Principal Investigator
  
  WAKABAYASHI Shigeo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  National Cardiovascular Center Research Institute
新規探索因子を用いた膜イオン輸送蛋白の細胞生理機能解析
- Principal Investigator
  
  重川宗一
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  National Cardiovascular Center Research Institute
A study on the mechanism of Na^+/Ca^<2+> exchange and its cellular role
- Principal Investigator
  
  SHIGEKAWA Munekazu
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  General physiology
- Research Institution
  National Cardiovascular Center Research Institute
カチオン交換輸送系の構造・機能相関の研究
- Principal Investigator
  
  重川宗一
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Cardiovascular Center Research Institute
新規探索因子を用いた膜イオン輸送蛋白の細胞生理機能解析
- Principal Investigator
  
  重川宗一
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Cardiovascular Center Research Institute
Regulation of the Na+/H+ exchanger and signal transductionPrincipal Investigator
- Principal Investigator
  
  WAKABAYASHI Shigeo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  National Cardiovascular Center Research Institute
カチオン交換輸送系の構造・機能相関の研究
- Principal Investigator
  
  重川宗一
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Cardiovascular Center Research Institute
Na^<+/>H^+交換輸送体の構造と機能・細胞外シグナルによる活性化のメカニズムPrincipal Investigator
- Principal Investigator
  
  若林繁夫
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  National Cardiovascular Center Research Institute
カチオン交換輸送系の構造・機能相関の研究
- Principal Investigator
  
  SHIGEKAWA Munekazu
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Cardiovascular Center Research Institute
Na^+/H^+交換輸送体の構造と機能-細胞外シグナルによる活性化のメカニズムPrincipal Investigator
- Principal Investigator
  
  若林繁夫
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  National Cardiovascular Center Research Institute
Molecular Mechanism of Function of Cation Antiporters.
- Principal Investigator
  
  SHIGEKAWA Munekazu
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  National Cardiovascular Center Research Institute
Na^+/H^+交換輸送体の構造と機能-細胞外シグナルによる活性化のメカニズムPrincipal Investigator
- Principal Investigator
  
  若林繁夫
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  National Cardiovascular Center Research Institute
Structure-function of the Na^+/H^+ exchanger : mechanism for growth factor activationPrincipal Investigator
- Principal Investigator
  
  WAKABAYASH Shigeo
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  National Cardiovascular Center Research Institute
筋小胞体Caポンプの分子機作の研究
- Principal Investigator
  
  重川宗一
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Cardiovascular Center Research Institute
A study on ion transport systems in heart muscle
- Principal Investigator
  
  SHIGEKAWA Munekazu
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  National Cardiovascular Center

[Book] Abnormal Ion Homeostasis and Cell Damage in Muscular Dystrophy. "Muscular Dystrophy (ed. By M. Hegde/A. Ankala)"2012
- Author(s)
  Iwata Y, Wakabayashi S
- Data Source
  KAKENHI-PROJECT-23390046
[Book] 子どもの心臓収縮と心肥大を調節する新しい制御蛋白質NCS-1 (2012) 循環器病研究の進歩(通巻52号)2012
- Author(s)
  西谷(中村)友重, 若林繁夫
- Data Source
  KAKENHI-PROJECT-23390046
[Book] 輸送体結合蛋白質の同定と複合体の構造解析"トランスポートソームの世界編 : 金井好克、竹島浩、森泰生、久保義弘"2011
- Author(s)
  若林繁夫他
- Publisher
  京都廣川書店
- Data Source
  KAKENHI-PROJECT-22659046
[Book] トランスポートソームの世界2011
- Author(s)
  若林繁夫, 他
- Publisher
  京都廣川書店
- Data Source
  KAKENHI-PROJECT-22659046
[Book] トランスポートソームの世界2011
- Author(s)
  若林繁夫, 他
- Publisher
  京都廣川書店
- Data Source
  KAKENHI-PROJECT-23390046
[Book] 輸送体結合蛋白質の同定と複合体の構造解析 " トランスポートソームの世界編:金井好克, 竹島浩, 森泰生, 久保義弘"2011
- Author(s)
  若林繁夫, 武田壮一, 久光隆
- Publisher
  京都廣川書店
- Data Source
  KAKENHI-PROJECT-23390046
[Book] トランスポートソームの世界-膜輸送研究の源流から未来へ−2011
- Author(s)
  若林繁夫、久光隆、武田壮一
- Publisher
  京都廣川書店
- Data Source
  KAKENHI-PROJECT-23590105
[Book] 筋変性疾患治療に向けたCa^<2+>透過チャネルを標的とした創薬の試み 2010 化学工業(61(4))2010
- Author(s)
  岩田裕子、若林繁夫
- Publisher
  化学工業社
- Data Source
  KAKENHI-PLANNED-18077015
[Book] Na^+/H^+交換輸送体:機能調節と薬物標的としての意義(創薬研究者必見!-最新トランスポーター研究2009 遺伝子医学MOOK122009
- Author(s)
  中村(西谷)友重、古林創史、久光隆、岩田裕子、若林繁夫
- Publisher
  (株)メディカルドウ
- Data Source
  KAKENHI-PLANNED-18077015
[Book] 機能調節と薬物標的としての意義(創薬研究者必見!-最新トランスポーター研究2009 "遺伝子医学MOOK12")2009
- Author(s)
  中村(西谷)友重、古林創史、久光隆、岩田裕子、若林繁夫
- Publisher
  (株)メディカルドゥ
- Data Source
  KAKENHI-PLANNED-18077015
[Book] 創薬研究者必見!-最新トランスポーター研究2009“遺伝子医学MOOK 12"2009
- Author(s)
  中村(西谷)友重、古林創史、久光隆、岩田裕子、若林繁夫
- Data Source
  KAKENHI-PROJECT-19390080
[Book] 遺伝子医学 MOOK 12号「最新トランスポーター研究2008」 (Na^+/H^+交換輸送体:機能調節と薬物標的としての意義)2008
- Author(s)
  中村(西谷)友重・古林創史・久光隆・岩田裕子・若林繁夫
- Publisher
  (株)メデイカルドウ
- Data Source
  KAKENHI-PROJECT-19590220
[Book] Na^+/H^+交換輸送体の構造・機能と病態的意義(循環器病研究の進歩通巻47号)2007
- Author(s)
  若林繁夫, 他
- Total Pages
  10
- Publisher
  協和企画
- Data Source
  KAKENHI-PLANNED-18077015
[Book] 動物細胞Na^+/H^+交換輸送体:分子から疾患まで (生化学 79/6)2007
- Author(s)
  若林繁夫, 他
- Total Pages
  9
- Publisher
  (社)日本生化学会
- Data Source
  KAKENHI-PROJECT-19390080
[Book] 動物細胞Na^+/H^+交換輸送体:分子から疾患まで生化学(79(6))2007
- Author(s)
  若林繁夫、久光隆、ユセフ・ベンアマー、中村(西谷)友重、岩田裕子
- Data Source
  KAKENHI-PLANNED-18077015
[Book] Na^+/H^+交換輸送体の構造・機能と病態的意義(循環器病研究の進歩通巻47号)2007
- Author(s)
  若林繁夫, 他
- Total Pages
  10
- Publisher
  協和企画
- Data Source
  KAKENHI-PROJECT-18059035
[Book] Na^+/H^+交換輸送体の構造・機能と病態的意義循環器病研究の進歩(通巻47号) Vol.XXVIII No.1(2007.11)2007
- Author(s)
  若林繁夫、岩田裕子、中村(西谷)友重、久光隆、ベンアマー・ヨセフ
- Publisher
  協和企画
- Data Source
  KAKENHI-PLANNED-18077015
[Book] 動物細胞Na^+/H^+交換輸送体:分子から疾患まで(生化学79/6)2007
- Author(s)
  若林繁夫, 他
- Total Pages
  9
- Publisher
  (社)日本生化学会
- Data Source
  KAKENHI-PLANNED-18077015
[Book] 動物細胞Na^+/H^+交換輸送体 : 分子から疾患まで (生化学79/6)2007
- Author(s)
  若林繁夫, 他
- Total Pages
  9
- Publisher
  (社)日本生化学会
- Data Source
  KAKENHI-PROJECT-17659241
[Book] Na^+/H^+交換輸送体の構造・機能と病態的意義 (循環器病研究の進歩通巻47号)2007
- Author(s)
  若林繁夫, 他
- Total Pages
  10
- Publisher
  協和企画
- Data Source
  KAKENHI-PROJECT-17659241
[Book] 動物細胞Na^+/H^+交換輸送体 : 分子から疾患まで(生化学)2007
- Author(s)
  若林繁夫他
- Publisher
  (社)日本生化学会(投稿中)
- Data Source
  KAKENHI-PLANNED-18077015
[Book] 創薬標的としてのイオントランスポーク・チャネルファーマビジョンニュース、collective Vol.32007
- Author(s)
  若林繁夫他
- Total Pages
  2
- Publisher
  (社)日本薬学会
- Data Source
  KAKENHI-PROJECT-17659241
[Book] Na+/H+交換輸送体の構造・機能と病態的意義循環器病研究の進歩2007
- Author(s)
  若林繁夫、岩田裕子、中村(西谷)友重、久光隆、ベンアマー・ヨセフ
- Data Source
  KAKENHI-PROJECT-19390080
[Book] 動物細胞Na^+/H^+交換輸送体:分子から疾患まで(2007) 生化学79(6)2007
- Author(s)
  若林繁夫、久光隆、ユセフ・ベンアマー、中村(西谷)友重、岩田裕子
- Data Source
  KAKENHI-PLANNED-18077015
[Book] 動物細胞Na^+/H^+交換輸送体 : 分子から疾患まで(生化学)2007
- Author(s)
  若林繁夫他
- Publisher
  (社)日本生化学会(投稿中)
- Data Source
  KAKENHI-PROJECT-18059035
[Book] Na^+/H^+交換輸送体の構造・機能と病態的意義循環器病研究の進歩(通巻47号)(Vol.XXVIII No.1(2007.11))2007
- Author(s)
  若林繁夫、岩田裕子、中村(西谷)友重、久光隆、ベンアマー・ヨセフ
- Publisher
  協和企画
- Data Source
  KAKENHI-PLANNED-18077015
[Book] Na^+/H^+交換輸送体の構造・機能と病態的意義(循環器病研究の進歩通巻47号)2007
- Author(s)
  若林繁夫, 他
- Total Pages
  10
- Publisher
  協和企画
- Data Source
  KAKENHI-PROJECT-19390080
[Book] 動物細胞Na+/H+交i換輸送体:分子から疾患まで(生化学79/6)2007
- Author(s)
  若林繁夫, 他
- Total Pages
  9
- Publisher
  (社)日本生化学会
- Data Source
  KAKENHI-PROJECT-18059035
[Book] Na^+/H^+交換輸送体 : 生体プロトン環境を制御するイオントランスポータ(Otology Japan 14/3)2004
- Author(s)
  若林繁夫他
- Total Pages
  6
- Publisher
  日本耳科学会
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Book] Two Fundamental Regulatory Factors of the Na+/H+ Exchangers : The Proton and CHP. "The Sodium-Hydrogen Exchange. From Molecule to its Role in Disease"2003
- Author(s)
  Wakabayashi, S., et al.
- Total Pages
  15
- Publisher
  Kluwer Academic Publishers
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Book] Na^+/H^+交換輸送体の構造と機能-活性に必須な因子としてのCHP-(心臓 34/4)2002
- Author(s)
  若林繁夫他
- Total Pages
  8
- Publisher
  日本心臓財団
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Book] 細胞内pH・容積センサーとしてのNa^+/H^+アンチポータ(生物物理 41/2)2001
- Author(s)
  若林繁夫
- Total Pages
  5
- Publisher
  日本生物物理学会
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Book] 動物細胞Na+/H+交換輸送体:分子から疾患まで生化学
- Author(s)
  若林繁夫、久光隆、ユセフ・ベンアマー、中村(西谷)友重、岩田裕子
- Data Source
  KAKENHI-PROJECT-19390080
[Journal Article] Exacerbation of autoimmune myocarditis by an immune checkpoint inhibitor is dependent on its time of administration in mice2020
- Author(s)
  Tsuruoka Kenjiro、Wakabayashi Shigeo、Morihara Hirofumi、Matsunaga Ninso、Fujisaka Yasuhito、Goto Isao、Imagawa Akihisa、Asahi Michio
- Journal Title
  
  International Journal of Cardiology
  
  Volume: S0167-5273 Pages: 34641-34648
- DOI
  10.1016/j.ijcard.2020.04.033
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08551, KAKENHI-PROJECT-19K16546, KAKENHI-PROJECT-19H01076
[Journal Article] Production of TRPV2-targeting functional antibody ameliorating dilated cardiomyopathy and muscular dystrophy in animal models2020
- Author(s)
  Yuko Iwata, Shigeo Wakabayashi, Shin Ito, Masafumi Kitakaze
- Journal Title
  
  Laboratory Investigation
  
  Volume: 100 Pages: 324-337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08551
[Journal Article] Reduced transient receptor potential vanilloid 2 expression in alveolar macrophages causes COPD in mice through impaired phagocytic activity2019
- Author(s)
  Masubuchi Hiroaki、Ueno Manabu、Maeno Toshitaka、Yamaguchi Koichi、Hara Kenichiro、Sunaga Hiroaki、Matsui Hiroki、Nagasawa Masahiro、Kojima Itaru、Iwata Yuko、Wakabayashi Shigeo、Kurabayashi Masahiko
- Journal Title
  
  BMC pulmonary medicine
  
  Volume: 19 Pages: 70-70
- DOI
  10.1186/s12890-019-0821-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09572, KAKENHI-PROJECT-16K19442, KAKENHI-PROJECT-19K11788, KAKENHI-PROJECT-17K08551, KAKENHI-PROJECT-17K09598
[Journal Article] Emerging Roles of Neuronal Ca2+ Sensor-1 in Cardiac and Neuronal Tissues2019
- Author(s)
  Nakamura TY., Nakao S, Wakabayashi S
- Journal Title
  
  Front Mol Neurosci
  
  Volume: 12 Pages: 56-56
- DOI
  10.3389/fnmol.2019.00056
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15017, KAKENHI-PROJECT-18K06867, KAKENHI-PROJECT-17K08551
[Journal Article] Overexpression of Na+/H+ exchanger 1 specifically induces cell death in human iPS cells via sustained activation of the Rho kinase ROCK2019
- Author(s)
  Shigeo Wakabayashi, Hirofumi Morihara, Shunichi Yokoe, Takatoshi Nakagawa, Kazumasa Moriwaki, Kiichiro Tomoda, Michio Asahi
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 294 Pages: 19577-19588
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08551
[Journal Article] Novel inhibitor　candidates　of　TRPV2　prevent　damage　of　dystrophic　myocytes　and　ameliorate　against　dilated　cardiomyopathy in a hamster model2018
- Author(s)
  Yuko Iwata, Yoshimi Katayama, Yasushi Okuno, Shigeo Wakabayashi
- Journal Title
  
  Oncotarget
  
  Volume: 9 Pages: 14042-14057
- DOI
  10.18632/oncotarget.24449
- NAID
  120006892046
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08551, KAKENHI-PROJECT-17K09598
[Journal Article] Tescalcin is a potential target of class I histone deacetylase inhibitors in neurons2017
- Author(s)
  Takamatsu G, Katagiri C, Tomoyuki T, Shimizu-Okabe C, Nakamura W, Nakamura-Higa M, Hayakawa T, Wakabayashi S, Kondo T, Takayama C, Matsushita M.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 482 Pages: 1327-1333
- DOI
  10.1016/j.bbrc.2016.12.036
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16J40160, KAKENHI-PROJECT-26430037, KAKENHI-PROJECT-26460312, KAKENHI-PROJECT-15K15033, KAKENHI-PROJECT-17K10311, KAKENHI-PROJECT-15K09161
[Journal Article] Cancer cachexia causes skeletal muscle damage via TRPV2-independent mechanism, unlike muscular dystrophy.2017
- Author(s)
  Yuko Iwata, Nobuyuki Suzuki, Hitomi Ohtake, Shinya Kamauchi, Naohiro Hashimoto, Tohru Kiyono, Shigeo Wakabayashi
- Journal Title
  
  Journal of cachexia, sarcopenia and muscle
  
  Volume: 印刷中 Pages: 1-11
- DOI
  10.1002/jcsm.12067
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10426, KAKENHI-PROJECT-26460312, KAKENHI-PROJECT-26461139, KAKENHI-PROJECT-25462531
[Journal Article] Possible Signaling Pathways Mediating Neuronal Calcium Sensor-1-Dependent Spatial Learning and Memory in Mice.2017
- Author(s)
  Tomoe Y Nakamura, Shu Nakao, Yukako Nakajo, Jun C Takahashi, Shigeo Wakabayashi, Hiroji Yanamoto
- Journal Title
  
  PLoS One
  
  Volume: 12 Pages: 1-1
- DOI
  10.1371/journal.pone.0170829
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460312, KAKENHI-PROJECT-15K08200
[Journal Article] Neuronal Ca2+ sensor-1 contributes to stress tolerance in cardiomyocytes via activation of mitochondrial detoxification pathways.2016
- Author(s)
  Tomoe Y Nakamura, Shu Nakao, Shigeo Wakabayashi
- Journal Title
  
  J Mol Cell Cardiol
  
  Volume: 99 Pages: 23-34
- DOI
  10.1016/j.yjmcc.2016.08.013
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460312, KAKENHI-PROJECT-15K08200
[Journal Article] Lack of TRPV2 impairs thermogenesis in mouse brown adipose tissue.2016
- Author(s)
  1.Sun, W., Uchida, K., Suzuki, Y., Zhou, Y., Kim, M., Takayama, Y., Takahashi, N., Goto, T., Wakabayashi, S., Kawada, T., Iwata, Y., and Tominaga, M
- Journal Title
  
  EMBO Reports
  
  Volume: 17 Pages: 383-399
- DOI
  10.15252/embr.201540819
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460312, KAKENHI-PLANNED-15H05928, KAKENHI-PROJECT-26461139, KAKENHI-PROJECT-15K19197
[Journal Article] Activation of TRPV2 negatively regulates the differentiation of mouse brown adipocytes2016
- Author(s)
  Sun W, Uchida K, Takahashi N, Iwata Y, Wakabayashi S, Goto T, Kawada T, Tominaga M.
- Journal Title
  
  Pfulugers Archiv-European Journal of Physiology
  
  Volume: 468 (9) Pages: 1527-1540
- DOI
  10.1007/s00424-016-1846-1
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-15H05928, KAKENHI-PROJECT-26460312, KAKENHI-PROJECT-26461139
[Journal Article] Stimulus-dependent regulation of nuclear Ca2+ signaling in cardiomyocytes: a role of neuronal calcium sensor-1.2015
- Author(s)
  2.Shu Nakao, Shigeo Wakabayashi, Tomoe Y. Nakamura. Stimulus-dependent regulation of nuclear Ca2+ signaling in cardiomyocytes: a role of neuronal calc
- Journal Title
  
  PLoS One
  
  Volume: 10
- DOI
  10.1371/journal.pone.0125050
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590293, KAKENHI-PROJECT-26460312, KAKENHI-PROJECT-15K08200, KAKENHI-PROJECT-25860174
[Journal Article] Calcineurin B homologous protein 3 negatively regulates cardiomyocyte hypertrophy via inhibition of glycogen synthase kinase 3 phosphorylation2015
- Author(s)
  Soushi Kobayashi, Tomoe Y. Nakamura, Shigeo Wakabayashi
- Journal Title
  
  Journal of Molecular Cellular Cardiology
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460312
[Journal Article] Calcineurin B homologous protein 3 negatively regulates cardiomyocyte hypertrophy via inhibition of glycogen synthase kinase 3 phosphorylation.2015
- Author(s)
  1.Soushi Kobayashi, Tomoe Y. Nakamura, Shigeo Wakabayashi.
- Journal Title
  
  J. Mol. Cell., Cardiol
  
  Volume: 未定 Pages: 133-42
- DOI
  10.1016/j.yjmcc.2015.04.018
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590293, KAKENHI-PROJECT-15K08200
[Journal Article] Calcineurin B homologous protein 3 negatively regulates cardiomyocyte hypertrophy via inhibition of glycogen synthase kinase 3 phosphorylation2015
- Author(s)
  4.Kobayashi S., Nakamura, T.Y., and Wakabayashi S.
- Journal Title
  
  J. Mol. Cell. Cardiol
  
  Volume: 84 Pages: 133-142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460312
[Journal Article] Osmosensation in TRPV2 dominant negative expressing skeletal muscle fibres.2015
- Author(s)
  3.Zanou, N., Mondin, L., Fuster, C., Seghers, F., Dufour, I., Clippele, M., Schakman, O., Tajeddine, N., Iwata, Y., Wakabayashi, S., Voets, T., Allard, B., and Gailly, P
- Journal Title
  
  J. Physiol.
  
  Volume: 593(17) Pages: 3849-3863
- DOI
  10.1113/jp270522
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460312
[Journal Article] Deficiency of a lipid droplet protein, Perilipin 5, suppresses myocardial lipid accumulation, thereby preventing type 1 diabetes-induced heart malfunction.2014
- Author(s)
  Kenta Kuramoto, Fumie Sakai, Nana Yoshinori, Tomoe Y. Nakamura, Shigeo Wakabayashi, Tomoko Kojidani, Tokuko Haraguchi, Fumiko Hirose,Takashi Osumi
- Journal Title
  
  Molecular Cellular Biology
  
  Volume: 34(14) Pages: 2721-2731
- DOI
  10.1128/mcb.00133-14
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-25116006, KAKENHI-PROJECT-25440053, KAKENHI-PROJECT-26291007, KAKENHI-PROJECT-26460312
[Journal Article] Na+/H+ exchanger 1 is regulated via its lipid-interacting domain which functions as a molecular switch: A pharmacological approach using indolocarbazole compounds.2014
- Author(s)
  Shimada-Shimizu N, Hisamitsu T, Nakamura TY, Hirayama N, Wakabayashi S
- Journal Title
  
  Molecular Pharmacology
  
  Volume: 85(1) Pages: 18-28
- DOI
  10.1124/mol.113.089268
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23390046, KAKENHI-PROJECT-23590105, KAKENHI-PROJECT-24590293, KAKENHI-PROJECT-26460091, KAKENHI-PROJECT-26460312
[Journal Article] Regulation of the cardiac Na+/H+ exchanger in health and disease2013
- Author(s)
  Wakabavashi S, Hisamitsu T, Nakamura TY
- Journal Title
  
  J Mol Cell Cardiol.
  
  Volume: (in press) Pages: 68-76
- DOI
  10.1016/j.yjmcc.2013.02.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659046, KAKENHI-PROJECT-23390046, KAKENHI-PROJECT-23590105, KAKENHI-PROJECT-24590293
[Journal Article] Identification and properties of a novel variant of NBC4 (Na^+/HCO_3^-co-transporter 4) that is predominantly expressed in choroid plexus.2013
- Author(s)
  Fukuda H. et al.
- Journal Title
  
  Biochem J.
  
  Volume: 450 Pages: 179-187
- DOI
  10.1042/bj20121515
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370029, KAKENHI-PROJECT-22659046, KAKENHI-PROJECT-23390046, KAKENHI-PROJECT-23591224
[Journal Article] Evidence that Na+/H+ exchanger 1 is an ATP-binding protein2013
- Author(s)
  Shimada-Shimizu N, Hisamitsu T, Nakamura TY, Wakabavashi S
- Journal Title
  
  ＦＥＢＳ　Ｊｏｕｒｎａｌ
  
  Volume: 280 Pages: 1430-1442
- DOI
  10.1111/febs.12138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659046, KAKENHI-PROJECT-23390046, KAKENHI-PROJECT-23590105, KAKENHI-PROJECT-24590293
[Journal Article] Decreased surface sialic acid content is a sensitive indicator of muscle damage2013
- Author(s)
  Iwata Y, Suzuki O, Wakabavashi S
- Journal Title
  
  Muscle & Nerve
  
  Volume: 47(3) Pages: 372-378
- DOI
  10.1002/mus.23632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659046, KAKENHI-PROJECT-23390046, KAKENHI-PROJECT-23591095
[Journal Article] Perilipin 5, a lipid droplet-binding protein, protects the heart from oxidativeburden by sequestering fatty acid from excessive oxidation2012
- Author(s)
  Kuramoto K, Okamura T, Yamaguchi T, Nakamura TY, et.al.
- Journal Title
  
  J Biol Chem.
  
  Volume: 287 Pages: 23852-23863
- DOI
  10.1074/jbc.m111.328708
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229002, KAKENHI-PROJECT-21590248, KAKENHI-PROJECT-22659046, KAKENHI-PROJECT-22700652, KAKENHI-PROJECT-23390046, KAKENHI-PROJECT-23390248, KAKENHI-PROJECT-23591356, KAKENHI-PROJECT-23790098, KAKENHI-PROJECT-24590293
[Journal Article] Diverse functions of neuronal calcium sensor-1(NCS-1) in excitable cells2012
- Author(s)
  Nakamura, TY, Wakabayashi, S
- Journal Title
  
  Trends in Cell & Molecular Biology
  
  Volume: Vol.7 Pages: 99-110
- URL
  http://www.researchtrends.net/tia/abstract.asp?in=0&vn=7&tid=55&aid=3601&pub=2012&type=3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390046
[Journal Article] Role of neuronal calcium sensor-1 in the cardiovascular system.2012
- Author(s)
  Nakamura TY, Wakabayashi S
- Journal Title
  
  Trends Cardiovasc. Med.
  
  Volume: 22(1) Pages: 12-17
- DOI
  10.1016/j.tcm.2012.06.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390046, KAKENHI-PROJECT-24590293
[Journal Article] Na^+/H^+ exchanger 1 directly binds to calcineurin A and activates downstream NEAT signaling, leading to cardiomyocyte hypertrophy.2012
- Author(s)
  Hisamitsu T, Nakamura TY, Wakabayashi S.
- Journal Title
  
  Mol. Cell. Biol.
  
  Volume: 32(16) Pages: 3265-3280
- DOI
  10.1128/mcb.00145-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590248, KAKENHI-PROJECT-22659046, KAKENHI-PROJECT-23390046, KAKENHI-PROJECT-23590105, KAKENHI-PROJECT-24590293
[Journal Article] Neuronal Calcium Sensor-1 Promotes Immature Heart Function and Hypertrophy by Enhancing Ca^<2+> Signals2011
- Author(s)
  Nakamura TY
- Journal Title
  
  Circ. Res
  
  Volume: 109(5) Pages: 512-23
- DOI
  10.1161/circresaha.111.248864
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220007, KAKENHI-PROJECT-21590248, KAKENHI-PROJECT-22659046, KAKENHI-PROJECT-23390046
[Journal Article] Novel phorbol ester-binding motif mediates hormonal activation of Na^+/H^+ exchanger.2010
- Author(s)
  Wakabayashi, S., Nakamura, T.Y., Kobayashi, S., Hisamitsu, T.
- Journal Title
  
  J Biol.Chem. 285(34)
  
  Pages: 26652-26661
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077015
[Journal Article] Novel phorbol ester-binding motif mediates hormonal activation of Na^+/H^+ exchanger.2010
- Author(s)
  Wakabayashi, S., et al.
- Journal Title
  
  J Biol.Chem.
  
  Volume: 285 Pages: 26652-26661
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077015
[Journal Article] Novel phorbol ester-binding motif mediates hormonal activation of Na^+/H^+ exchanger.2010
- Author(s)
  Wakabayashi, S., et al.
- Journal Title
  
  J Biol.Chem.
  
  Volume: 285 Pages: 26652-26661
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659046
[Journal Article] Novel phorbol ester-binding motif mediates hormonal activation of Na^+/H^+ exchanger.2010
- Author(s)
  Wakabayashi S, Nakamura TY, Kobayashi S, Hisamitsu T
- Journal Title
  
  J Biol. Chem.
  
  Volume: 285 Pages: 26652-26661
- DOI
  10.1074/jbc.m110.130120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590248, KAKENHI-PROJECT-22659046
[Journal Article] Dominant-negative inhibition of Ca^<2+> influx via TRPV2 ameliorates muscular dystrophy in animal models.2009
- Author(s)
  Iwata, Y., Katanosaka, Y., Arai, Y., Shigekawa, M., Wakabayashi, S.
- Journal Title
  
  Hum.Mol.Genet. 18(5)
  
  Pages: 824-834
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077015
[Journal Article] Essential role of TRPV2 ion channel in the sensitivity of dystrophic muscle to eccentric contractions.2009
- Author(s)
  Zanou, N., Iwata, Y., Schakman, O., Lebacq, J., Wakabayashi, S., Gailly, P.
- Journal Title
  
  FEBS Lett. 583(22)
  
  Pages: 3600-3604
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077015
[Journal Article] Dominant-negative inhibition of Ca^<2+> influx via TRPV2 ameliorates muscular dystrophy in animal models.2009
- Author(s)
  Iwata, Y., Katanosaka, Y., Arai, Y., Shigekawa, M., Wakabayashi, S.
- Journal Title
  
  Hum. Mol. Gen 18(5)
  
  Pages: 824-834
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077015
[Journal Article] A Model of Na^+/H^+ Exchanger and Its Central Role in Regulation of pH and Na^+ in Cardiac Myocytes.2009
- Author(s)
  Cha, C.Y., Oka, C., Earm, Y.E., Wakabayashi, S., Noma, A.
- Journal Title
  
  Biophys. J 97(10)
  
  Pages: 2674-2683
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077015
[Journal Article] Dominant-negative inhibition of Ca2+ influx via TRPV2 ameliorates muscular dystrophy in animal models2009
- Author(s)
  Iwata, Y., Katanosaka, Y., Arai, Y., Shigekawa, M., Wakabayashi, S
- Journal Title
  
  Hum. Mol. Gen Vol.18,No.5
  
  Pages: 824-834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390080
[Journal Article]2008
- Author(s)
  中村(西谷)友重, 古林創史, 久光隆, 岩田裕子, 若林繁夫
- Journal Title
  
  Na^+/H^+交換輸送体:機能調節と薬物標的としての意義。遺伝子屠学MOOK12号「最新トランスポーター研究2008」((株)メデイカルドウ)
  
  Pages: 255-260
- Data Source
  KAKENHI-PROJECT-19590220
[Journal Article] Activation of Na^+/H^+ exchanger 1 is sufficient to generate Ca^<2+> signals that induce cardiac hypertrophy and heart failure.2008
- Author(s)
  Nakamura, T.Y., Iwata, Y., Arai, Y., Komamura, K., Wakabayashi, S.
- Journal Title
  
  Circ. Res 103(8)
  
  Pages: 891-899
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077015
[Journal Article] Activation of Na^+/H^+ exchanger 1 is sufficient to genera to Ca^<2+> signals that induce cardiac hypertrophy and heart failure2008
- Author(s)
  Nakamura TY, Iwata Y, Arai Y, Komamura K, Wakabayashi S
- Journal Title
  
  Circ Res 103
  
  Pages: 891-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590220
[Journal Article] Activation of Na+/H+ exchanger 1 is sufficient to generate Ca2+ signals that induce cardiac hypertrophy and heart failure2008
- Author(s)
  Nakamura, T.Y., Iwata, Y., Arai, Y., Komamura, K., Wakabayashi, S
- Journal Title
  
  Circ. Res Vol.103/No.8
  
  Pages: 891-899
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390080
[Journal Article] Activation of Na^+/H^+ exchanger 1 is sufficient to generate Ca^<2+> signals that induce cardiac hypertrophy and heart failure2008
- Author(s)
  Nakamura TY, Iwata Y, Arai Y, Komamura K, Wakabayashi S
- Journal Title
  
  Circ Res. 8
  
  Pages: 891-899
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590220
[Journal Article] Activation of Na^+/H^+ exchanger 1 is sufficient to generate Ca^<2+> signals that induce cardiac hypertrophy and heart failure.2008
- Author(s)
  Nakamura, T.Y., Iwata, Y., Arai, Y., Komamura, K., Wakabayashi, S.
- Journal Title
  
  Circ.Res. 103(8)
  
  Pages: 891-899
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077015
[Journal Article] Functional importance of charged residues within the putat ive intracellular loops in pH regula tion by Na^+/ H^+ exchanger NHE12007
- Author(s)
  Hisamitsu T, Yamada K, Nakamura TY, Wakabayashi S
- Journal Title
  
  FEBS J. 274
  
  Pages: 4326-4335
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590220
[Journal Article] Regulation of the cardiac na+/ca2+ exchanger by calcineurin and protein kinase C.2007
- Author(s)
  Shigekawa M, Katanosaka Y, Wakabayashi S
- Journal Title
  
  Ann N Y Acad Sci. 1099
  
  Pages: 53-63
- Data Source
  KAKENHI-ORGANIZER-18077014
[Journal Article] Enhanced Na+/H+ exchange activity contributes to the pathogenesis of muscular dystrophy via involvement of P2 receptors2007
- Author(s)
  Iwata, Y., Katanosaka, Y., Hisamitsu, T., Wakabayashi, S
- Journal Title
  
  Am. J. Pathol Vol.171/No.5
  
  Pages: 1576-1587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390080
[Journal Article] Dimerization is crucial for the function of the Na^+/H^+ exchanger NHE1.2006
- Author(s)
  Hisamitsu, T., Ben Ammar, Y., Nakamura, T.Y., Wakabayashi, S.
- Journal Title
  
  Biochemistry 45(44)
  
  Pages: 13346-13355
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077015
[Journal Article] Crystal structure of CHP2 complexed with NHE1-cytosolic region and an implication for pH regulation2006
- Author(s)
  Ben Ammar, Y., Takeda, S., Hisamitsu, T., Mori, H., Wakabayashi, S.
- Journal Title
  
  EMBO J. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Crystal structure of CHP2 complexed with NHE1-cytosolic region and an implication for pH regulation.2006
- Author(s)
  Ben Ammar, Y., Takeda, S., Hisamitsu, T., Mori. H., Wakabayashi, S.
- Journal Title
  
  EMBO J. 25
  
  Pages: 2315-2325
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077015
[Journal Article] Crystal structure of CHP2 complexed with NHE1-cytosolic region and an implication for pH regulation.2006
- Author(s)
  Ben Ammar, Y., Takeda, S., Hisamitsu, T., Mori. H., Wakabayashi, S
- Journal Title
  
  EMBO J 25(11)
  
  Pages: 2315-2325
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077015
[Journal Article] Identification and characterization of GSRP-56, a novel Golgi-localized spectrin-repeat containing protein2006
- Author(s)
  Kobayashi, Y., Katanosaka, Y., Iwata, Y., Shigekawa, M., Wakabayashi, S.
- Journal Title
  
  Exp. Cell Res. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Novel Role of Neuronal Ca2+ Sensor 1 as a Survival Factor Up-Regulated in Injured Neurons2006
- Author(s)
  Nakamura, T.Y., Jeromin, A., Smith, G., Kurushima, H., Koga, H., Nakabeppu, Y., Wakabayashi, S., Nabekura, J.
- Journal Title
  
  J. Cell Biol. 172(7)
  
  Pages: 1081-1091
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Dimerization is crucial for function of the Na+/H+ Exchanger NHE1.2006
- Author(s)
  Hisamitsu, T., Ben Ammar, Y., Nakamura, T.Y., Wakabayashi, S.
- Journal Title
  
  J. Mol. Biol. (submit)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Cardiac Syntrophin Isoforms : Species-Dependent Expression, Association with Dystrophin Complex and Subcellular Localization2005
- Author(s)
  Iwata, Y., Shigekawa, M., Wakabayashi, S.
- Journal Title
  
  Mol. Cell. Biochem. 268
  
  Pages: 59-66
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Calcineurin Inhibits Na+/Ca2+ Exchange in Phenylephrine-treated Hypertrophic Cardiomyocytes2005
- Author(s)
  Katanosaka, Y., Iwata, Y., Kobayashi, Y., Shibasaki, F., Wakabayashi, S., Shigekawa, M.
- Journal Title
  
  J. Biol. Chem. 280(7)
  
  Pages: 5764-5772
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Crystallization and preliminary crystallographic analysis of the human calcineurin homologous protein CHP2 bound to the cytoplasmic region of the Na+/H+ exchanger NHE12005
- Author(s)
  Ben Ammar, Y., Takeda, S., Sugawara, M., Miyano, M., Mori, H., Wakabayashi, S.
- Journal Title
  
  Acta Crystallographica Section F 61(10)
  
  Pages: 956-958
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Species-Dependent Expression, Association with Dystrophin Complex and Subcellular Localization2005
- Author(s)
  Iwata, Y., Shigekawa, M., Wakabayashi S
- Journal Title
  
  Mol.Cell.Biochem. 268
  
  Pages: 59-66
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Mitochondrial dysfunction is related to necrosis-like programmed cell death induced by A23187 in CEM cells2005
- Author(s)
  Hamahata, K., Adachi, S., Matsubara, H., Okada, M., Imai, T., Watanabe, K., Toyokuni, S., Ueno, M., Wakabayashi, S., Katanosaka, Y., Akiba, S., Kubota, M., Nakabata, T.
- Journal Title
  
  Eur. J. Pharmacol. 516
  
  Pages: 187-196
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Calcineurin Inhibits Na^+/Ca^<2+> Exchange in Phenylephrine-treated Hypertrophic Cardiomyocytes.2005
- Author(s)
  Katanosaka, Y., Iwata, Y., Kobayashi, Y., Shibasaki, F., Wakabayashi, S., Shigekawa, M.
- Journal Title
  
  J.Biol.Chem. 280(7)
  
  Pages: 5764-5772
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Protective effects of Ca2+ handling drugs against abnormal Ca2+ homeostasis and cell damage in myopathic skeletal muscle cells2005
- Author(s)
  Iwata, Y., Katanosaka, Y., Zhu, S., Kobayashi, Y., Hanada, H., Shigekawa, M., Wakabayashi, S.
- Journal Title
  
  Biochem. Pharmacol. 70
  
  Pages: 740-751
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Dimeric Interaction between the Cytoplasmic Domains of the Na+/H+ Exchanger NHE1 Revealed by Symmetrical Intermolecular Cross-Linking and Selective Co-Immunoprecipitation2004
- Author(s)
  Hisamitsu, T., Pang, T., Shigekawa, M., Wakabayashi, S.
- Journal Title
  
  Biochemistry 43(34)
  
  Pages: 11135-11143
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Role of Calcineurin B Homologous Protein in pH Regulation by the Na+/H+ Exchanger 1 : Tightly Bound Ca2+ Ions as Important Structural Elements2004
- Author(s)
  Pang, T., Hisamitsu, T., Mori, H., Shigekawa, M., Wakabayashi, S.
- Journal Title
  
  Biochemistry 43(12)
  
  Pages: 3628-3636
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Association of Genetic Polymorphisms of Sodium-Calcium Exchanger 1, NCX1, with Hypertension in a Japanese General Population.2004
- Author(s)
  Kokubo, Y., Inamoto, N., Tomoike, H., Kamide, K., Takiuchi, S., Kawano, Y., Tanaka, C., Katanosaka, Y., Wakabayashi, S., Shigekawa M., Hishikawa, O., Miyata, T.
- Journal Title
  
  J.Hypertension 27(10)
  
  Pages: 697-702
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Syntrophin is an actin-binding protein the cellular localization of which is regulated through cytoskeletal reorganization in skeletal muscle cells2004
- Author(s)
  Iwata, Y., Sampaolesi, M., Shigekawa, M., Wakabayashi, S.
- Journal Title
  
  Eur. J. Cell Biol. 83
  
  Pages: 555-565
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Association of Genetic Polymorphisms of Sodium-Calcium Exchanger 1 Gene, NCX1, with Hypertension in a Japanese General Population.2004
- Author(s)
  Kokubo, Kokubo, Y., Inamoto, N., Tomoike, H., Kamide, K., Takiuchi, S., Kawano, Y., Tanaka, C., Katanosaka, Y., Wakabayashi, S., Shigekawa, M., Hishikawa, 0., Miyata, T.
- Journal Title
  
  Hypertension Res. 27(10)
  
  Pages: 697-702
- NAID
  10014224275
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Dimeric Interaction between the Cytoplasmic Domains of the Na^+/H^+ Exchanger NHE1 Revealed by Symmetrical Intermolecular Cross-Linking and Selective Co-Immunoprecipitation.2004
- Author(s)
  Hisamitsu, T., Pang, T., Shigekawa, M., Wakabayashi, S.
- Journal Title
  
  Biochemistry 43(34)
  
  Pages: 11135-11143
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Na^+/H^+交換輸送体:生体プロトン環境を制御するイオントランスポータ2004
- Author(s)
  若林繁夫, 久光隆, 厖天翔
- Journal Title
  
  Otology Japan 14(3)
  
  Pages: 262-267
- NAID
  10020400895
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Syntrophin is an Actin-binding Protein Whose Cellular Localization is Regulated through Cytoskeletal Reorganization in Skeletal Muscle Cells.2004
- Author(s)
  Iwata, Y., Sampaolesi, M., Shigekawa, M., Wakabayashi, S.
- Journal Title
  
  Eur.J.Cell Biol. 83
  
  Pages: 555-565
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Two Fundamental Regulatory Factors of the Na+/H+ Exchangers; The Proton and CHP. The Sodium-Hydrogen Exchange; From Molecule to its Role in Disease (Ed. by Karmazyn, M., Avkiran, M., Fliegel, L.)2003
- Author(s)
  Wakabayashi, S., Pang, T., Hisamitsu, T., Shigekawa, M.
- Journal Title
  
  Kluwer Academic Publishers 35-49
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Kinetic dissection of two distinct proton binding sites in Na^+/H+ exchangers by measurement of reverse mode reaction.2003
- Author(s)
  Wakabayashi, S., et al.
- Journal Title
  
  J.Biol. Chem. 278(44)
  
  Pages: 43580-43585
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Evidence for involvement of the putative first extracellular loop in differential volume-sensitivity of the Na+/H+ exchangers NHE1 and NHE22003
- Author(s)
  Su, X., Pang, T., Wakabayashi, S., Shigekawa, M.
- Journal Title
  
  Biochemistry 42(4)
  
  Pages: 1086-1094
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Mutations of Arg440 and Gly455/Gly456 Oppositely Change pH-Sensing of Na^+/H^+ Exchanger NHE1.2003
- Author(s)
  Wakabayashi, S., et al.
- Journal Title
  
  J.Biol.Chem. 278(14)
  
  Pages: 11828-11835
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Kinetic dissection of two distinct proton binding sites in Na+/H+ exchangers by measurement of reverse mode reaction2003
- Author(s)
  Wakabayashi, S., Hisamitsu, T., Pang, T., Shigekawa, M.
- Journal Title
  
  J. Biol. Chem. 278(44)
  
  Pages: 43580-43585
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Mutations of Arg440 and G1y455/G1y456 Oppositely Change pH-Sensing of Na+/H+ exchanger NHE12003
- Author(s)
  Wakabayashi, S., Hisamitsu, T., Pang, T., Shigekawa, M.
- Journal Title
  
  J. Biol. Chem. 278(14)
  
  Pages: 11828-11835
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Mechanism of acid adaptation of a fish living in a pH 3.5 lake2003
- Author(s)
  Hirata, T., Kaneko, T., Ono, T., Nakazato, T., Furukawa, N., Hasegawa, S., Wakabayashi, S., Shigekawa, M., Chang, M.-H., Romero M., Hirose, S.
- Journal Title
  
  Am J Physiol 284(5)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Expression of Calcineurin B Homologous Protein 2 Protects Serum Deprivation-Induced Cell Death by Serum-Independent Activation of Na+/H+ exchanger 1.2002
- Author(s)
  Pang, T., Wakabayashi, S., Shigekawa, M.
- Journal Title
  
  J. Biol. Chem. 277(46)
  
  Pages: 43771-43777
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Calcineurin-homologous protein as an essential cofactor for Na+/H+ exchangers.2001
- Author(s)
  Pang, T., Su, X., Wakabayashi, S., and Shigekawa, M.
- Journal Title
  
  J. Biol. Chem. 276(20)
  
  Pages: 17367-17372
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Structure-Function of the Na^+/H^+ exchangers. Role of interacting proteins.2001
- Author(s)
  Wakabayashi, S.et al.
- Journal Title
  
  Kidney Int. 60
  
  Pages: 403-404
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] NHE6 protein possesses a signal peptide destined for endoplasmic reticulum membrane and localizes in secretory organelles of the cell.2001
- Author(s)
  Miyazaki, E., Sakaguchi, M., Wakabayashi, S., Shigekawa, M., Mihara, K.
- Journal Title
  
  J. Biol. Chem. 276(52)
  
  Pages: 49221-49227
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Journal Article] Structure-Function of the Na+/H+ exchangers. Role of interacting proteins2001
- Author(s)
  Wakabayashi, S., Pang, T., Su, X., Shigekawa, M.
- Journal Title
  
  Kidney Int. 60
  
  Pages: 403-404
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13142210
[Patent] 抗TRPV2抗体2010
- Inventor(s)
  岩田裕子, 若林繁夫
- Industrial Property Rights Holder
  (財)ヒューマンサィエンス振興財団
- Industrial Property Number
  2010-016760
- Filing Date
  2010-01-28
- Data Source
  KAKENHI-PLANNED-18077015
[Patent] 抗TRPV2抗体2010
- Inventor(s)
  岩田裕子, 若林繁夫
- Industrial Property Rights Holder
  (財)ヒューマンサイエンス振興財団
- Industrial Property Number
  2010-016760
- Filing Date
  2010-01-28
- Data Source
  KAKENHI-PROJECT-19390080
[Patent] 抗TRPV2抗体2010
- Inventor(s)
  岩田裕子、若林繁夫
- Industrial Property Rights Holder
  (財)ヒューマンサイエンス振興財団
- Industrial Property Number
  2010-001676
- Filing Date
  2010-01-28
- Data Source
  KAKENHI-PROJECT-19390080
[Patent] 抗TRPV2抗体2010
- Inventor(s)
  岩田裕子、若林繁夫
- Industrial Property Rights Holder
  (財)ヒューマンサイエンス振興財団
- Filing Date
  2010-01-28
- Data Source
  KAKENHI-PLANNED-18077015
[Patent] TRPV2の部分ペプチド2009
- Inventor(s)
  岩田裕子、若林繁夫
- Industrial Property Rights Holder
  (財)ヒューマンサイエンス振興財団
- Industrial Property Number
  2009-186219
- Filing Date
  2009-08-11
- Data Source
  KAKENHI-PROJECT-19390080
[Patent] TRPV2の部分ペプチド2009
- Inventor(s)
  岩田裕子, 若林繁夫
- Industrial Property Rights Holder
  (財)ヒューマンサイエンス振興財団
- Industrial Property Number
  2009-186219
- Filing Date
  2009-08-11
- Data Source
  KAKENHI-PROJECT-19390080
[Patent] TRPV2の部分ペプチド2009
- Inventor(s)
  岩田裕子, 若林繁夫
- Industrial Property Rights Holder
  (貝オ)ヒューマンサイエンス振興財団
- Industrial Property Number
  2009-186219
- Filing Date
  2009-08-11
- Data Source
  KAKENHI-PLANNED-18077015
[Patent] TRPV2の部分ペプチド2009
- Inventor(s)
  岩田裕子、若林繁夫
- Industrial Property Rights Holder
  (財)ヒューマンサイエンス振興財団
- Filing Date
  2009-08-11
- Data Source
  KAKENHI-PLANNED-18077015
[Patent] 目的物質精製用タグおよび精製用タグを用いた目的物資の精製方法2007
- Inventor(s)
  若林繁夫
- Industrial Property Rights Holder
  (財)ヒューマンサィエンス振興財団
- Industrial Property Number
  2007-130239
- Filing Date
  2007-05-16
- Data Source
  KAKENHI-PROJECT-18059035
[Patent] トランスジェニック非ヒト動物2007
- Inventor(s)
  岩田裕子, 西谷友重, 若林繁夫
- Industrial Property Rights Holder
  (財)ヒューマンサィエンス振興財団
- Industrial Property Number
  2007-123514
- Filing Date
  2007-05-08
- Data Source
  KAKENHI-PROJECT-18059035
[Patent] 目的物質精製用タグおよび精製用タグを用いた目的物資の精製方法2007
- Inventor(s)
  若林繁夫
- Industrial Property Rights Holder
  (財)ヒューマンサィエンス振興財団
- Industrial Property Number
  2007-130239
- Filing Date
  2007-05-16
- Data Source
  KAKENHI-PLANNED-18077015
[Patent] TRPV2阻害剤、疾患の予防又は治療剤、薬剤探索用リード化合物、及び薬剤探索方法2007
- Inventor(s)
  岩田裕子, 若林繁夫
- Industrial Property Rights Holder
  (財)ヒューマンサイエンス振興財団
- Filing Date
  2007-12-18
- Data Source
  KAKENHI-PROJECT-17659241
[Patent] トランスジェニック非ヒト動物2007
- Inventor(s)
  岩田裕子, 西谷友重, 若林繁夫
- Industrial Property Rights Holder
  (財)ヒューマンサィエンス振興財団
- Industrial Property Number
  2007-123514
- Filing Date
  2007-05-08
- Data Source
  KAKENHI-PLANNED-18077015
[Patent] 目的物質精製用タグおよび精製用タグを用いた目的物質の精製方法2007
- Inventor(s)
  若林繁夫
- Industrial Property Rights Holder
  (財)ヒューマンサイエンス振興財団
- Filing Date
  2007-05-16
- Data Source
  KAKENHI-PLANNED-18077015
[Patent] トランスジェニック非ヒト動物2007
- Inventor(s)
  岩田裕子、西谷友重、若林繁夫
- Industrial Property Rights Holder
  (財)ヒューマンサイエンス振興財団
- Filing Date
  2007-05-08
- Data Source
  KAKENHI-PLANNED-18077015
[Patent] 目的物質精製用タグおよび精製用タグを用いた目的物質の精製方法2007
- Inventor(s)
  若林繁夫
- Industrial Property Rights Holder
  (財)ヒューマンサイエンス振興財団
- Filing Date
  2007-05-16
- Data Source
  KAKENHI-PLANNED-18077015
[Patent] 目的物質精製用タグおよび精製用タグを用いた目的物質の精製方法2007
- Inventor(s)
  若林繁夫
- Industrial Property Rights Holder
  (財)ヒューマンサイエンス振興財団
- Industrial Property Number
  2007-130239
- Filing Date
  2007-05-16
- Data Source
  KAKENHI-PROJECT-19390080
[Patent] トランスジェニック非ヒト動物2007
- Inventor(s)
  岩田裕子,西谷友重,若林繁夫
- Industrial Property Rights Holder
  (財)ヒューマンサイエンス振興財団
- Industrial Property Number
  2007-123514
- Filing Date
  2007-05-08
- Data Source
  KAKENHI-PROJECT-19390080
[Patent] トランスジェニック非ヒト動物2007
- Inventor(s)
  岩田裕子、西谷友重、若林繁夫
- Industrial Property Rights Holder
  (財)ヒューマンサイエンス振興財団
- Filing Date
  2007-05-08
- Data Source
  KAKENHI-PLANNED-18077015
[Patent] 目的物質精製用タグおよび精製用タグを用いた目的物資の精製方法2007
- Inventor(s)
  若林繁夫
- Industrial Property Rights Holder
  (財)ヒューマンサイエンス振興財団
- Industrial Property Number
  2007-130239
- Filing Date
  2007-05-16
- Data Source
  KAKENHI-PROJECT-19390080
[Patent] トランスジェニック非ヒト動物2007
- Inventor(s)
  岩田裕子、西谷友重、若林繁夫
- Industrial Property Rights Holder
  (財)ヒューマンサイエンス振興財団
- Industrial Property Number
  2007-123514
- Filing Date
  2007-05-08
- Data Source
  KAKENHI-PROJECT-19390080
[Patent] TRPV2特異的アッセイ方法およびTRPV2特異的薬剤スクリーニング方法2006
- Inventor(s)
  若林繁夫, 岩田裕子
- Industrial Property Rights Holder
  財団法人ヒューマンサイエンス振興財団
- Filing Date
  2006-03-28
- Data Source
  KAKENHI-PROJECT-17659241
[Presentation] Overexpression of the Na+/H+ exchanger NHE1 induces selective cell death of human iPS cells via sustained activation of rho kinase ROCK2019
- Author(s)
  Shigeo Wakabayashi, Kiichiro Tomoda, Shunichi Yokoe, Hirofumi Morihara, Michio Asahi
- Organizer
  第92回日本生化学会
- Data Source
  KAKENHI-PROJECT-17K08551
[Presentation] Overexpression of NHE1 induces a selective cell death of human iPS cells viathesustainedactivationofrhokinase ROCK2019
- Author(s)
  Shigeo Wakabayashi, Kiichiro Tomoda, Shunichi Yokoe, Hirofumi Morihara, Michio Asahi
- Organizer
  アジア・オセアニア生理学会連合大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08551
[Presentation] Overexpression of the Na+/H+ exchanger NHE1 induces selective cell death of human iPS cells via sustained activation of rho kinase ROCK.2019
- Author(s)
  Shigeo Wakabayashi, Kiichiro Tomoda, Shunichi Yokoe, Hirofumi Morihara, Michio Asahi
- Organizer
  京都大学iPS細胞研究所シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08551
[Presentation] Function analysis of NHE1 using a strategy of cardiomyocyte differentiation from human iPS cells2019
- Author(s)
  Shigeo Wakabayashi, Kiichiro Tomoda, Shunichi Yokoe, Hirofumi Morihara, Michio Asahi
- Organizer
  日本生理学会大会　FAOPS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08551
[Presentation] Na+/H+交換輸送体NHE1の過剰発現は、RhoキナーゼROCKの持続的活性化を介してヒトiPS細胞の選択的細胞死を誘導する2019
- Author(s)
  若林繁夫、友田紀一郎、朝日通雄
- Organizer
  近畿生理学談話会
- Data Source
  KAKENHI-PROJECT-17K08551
[Presentation] ヒトiPS細胞からの心筋分化系を用いた形質膜Na+/H+交換輸送体の機能解析2018
- Author(s)
  若林繁夫、友田紀一郎、横江俊一、森原啓文、朝日通雄
- Organizer
  日本生化学会年会
- Data Source
  KAKENHI-PROJECT-17K08551
[Presentation] ヒトiPS細胞からの心筋分化系を用いた心筋に高発現するCa2+結合蛋白質CHP3の機能解析2017
- Author(s)
  若林繁夫、友田紀一郎、金美花、横江俊一、森原啓文、朝日通雄
- Organizer
  Conbio生命科学系合同年会
- Data Source
  KAKENHI-PROJECT-17K08551
[Presentation] A Novel Role of Calcineurin B Homologous Protein 3 in Hypoxia-induced Cardiac Hypertrophy and Heart Failure2017
- Author(s)
  MeiHua Jin, Shigeo Wakabayashi, Soushi Kobayashi, Hirotsugu Tsuchimochi, Mikiyasu Shirai, James T. Pearson, Takeshi Ogo.
- Organizer
  The 94th Annual Meeting of the Phisiological Society
- Place of Presentation
  Hamamatu
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-15K18975
[Presentation] Novel mechanism of stress tolerance of cardiomyocytes mediated by a Ca2+ sensor protein NCS-12017
- Author(s)
  Tomoe Y. Nakamura, Shu Nakao, Shigeo Wakabayashi
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-15K08200
[Presentation] ヒトiPS細胞からの心筋分化系を用いた遺伝子の機能解析2017
- Author(s)
  若林繁夫、友田紀一郎、朝日通雄
- Organizer
  第110回近畿生理学談話会
- Data Source
  KAKENHI-PROJECT-17K08551
[Presentation] カルシニュリンB様蛋白質3（CHP3）ノックアウトマウスを用いた慢性低酸素負荷による心肥大2017
- Author(s)
  金　美花、若林　繁夫、古林創史、土持　裕胤、白井　幹康、ピアソン　ジェームズ、
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  浜松アクトシティコングレスセンター
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-26460312
[Presentation] 心筋に高発現するCHP3はAkt/GSK3βシグナルを介して心筋細胞肥大を抑制する2017
- Author(s)
  古林創史、西谷友重、金美花、若林繁夫
- Organizer
  近畿生理談話会
- Data Source
  KAKENHI-PROJECT-15K08200
[Presentation] カルシニュリンB様蛋白質3（CHP3）ノックアウトマウスの作成と心機能解析2016
- Author(s)
  金美花、若林繁夫、古林創史、土持裕胤、白井幹康
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-26460312
[Presentation] 心筋細胞における核内Ca2+濃度制御機構とCa2+センサーNCS-1の役割2016
- Author(s)
  西谷（中村）友重、中尾周、若林繁夫
- Organizer
  生理学研究所　研究会2016
- Place of Presentation
  九州大学
- Year and Date
  2016-10-24
- Data Source
  KAKENHI-PROJECT-15K08200
[Presentation] 細胞内Ca2+センサーによるミトコンドリア機能制御と心筋ストレス防御2016
- Author(s)
  西谷（中村）友重、若林繁夫、中川修
- Organizer
  第26回日本循環薬理学会
- Place of Presentation
  信州大学医学部
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-15K08200
[Presentation] マウスの空間学習・記憶におけるカルシウムセンサーNCS-1の役割とシグナル伝達経路2016
- Author(s)
  中村（西谷）友重、中尾周、中城有香子、若林繁夫、柳本広二
- Organizer
  第109回　近畿生理学談話会
- Place of Presentation
  大阪市立大学医学部
- Year and Date
  2016-11-05
- Data Source
  KAKENHI-PROJECT-15K08200
[Presentation] Production of calcineurin B homologous protein 3 knockout mice and analysis of cardiac function2016
- Author(s)
  Shigeo Wakabayashi,MeiHua Jin, Soushi Kobayashi, Hirotsugu Tsuchimochi, Mikiyasu Shirai
- Organizer
  The 93th Annual Meeting of the Phisiological Society
- Place of Presentation
  Sapporo, Japan
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-15K18975
[Presentation] マウス大動脈狭窄心不全モデルにおける果実に含有するポリフェノール類の病態改善効果の検討2016
- Author(s)
  若林繁夫、スクマラン・ビジェヤクマ、金美花、稲垣薫克、土持裕胤、白井幹康
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26460312
[Presentation] Divergent roles of neuronal Ca2+ sensor-1 in immature and diseased hearts2016
- Author(s)
  Tomoe Y. Nakamura-Nishitani1, Shu Nakao, and Shigeo Wakabayashi
- Organizer
  医工連携国際シンポジウム2016
- Place of Presentation
  東京医科歯科大学
- Year and Date
  2016-07-11
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08200
[Presentation] Regulation of energy metabolism by intracellular Ca2+ signals2015
- Author(s)
  Nakamura-Nishitani, T.Y., Nakao, S., Nakagawa, O., Wakabayashi, S
- Organizer
  第92回日本生理学会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2015-03-23
- Data Source
  KAKENHI-PROJECT-26460312
[Presentation] Effects of Epac-specific inhibitor, ESI-09 on heart failure model mice2015
- Author(s)
  Jin , M., Wakabayashi, S., Tsuchimochi, H., Shirai, M.
- Organizer
  第92回日本生理学会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2015-03-22
- Data Source
  KAKENHI-PROJECT-26460312
[Presentation] 細胞内Ca2+センサーによる新規代謝調節経路2015
- Author(s)
  西谷（中村）友重、中尾周、中川修、若林繁夫
- Organizer
  BMB2015　第38回　日本分子生物学会年会　第88回日本生化学会　合同大会
- Place of Presentation
  神戸国際会議場・展示場
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26460312
[Presentation] Cardioprotective Role of Neuronal Ca2+-Sensor -1 during Stress2015
- Author(s)
  Nakamura, T.Y., Nakao, S., Wakabayashi, S
- Organizer
  Biophysical Society 59th Annual Meeting
- Place of Presentation
  Baltimore, USA
- Year and Date
  2015-02-11
- Data Source
  KAKENHI-PROJECT-26460312
[Presentation] 細胞内Ca2+センサー蛋白質を介した心筋内ストレス防御機構2015
- Author(s)
  西谷（中村）友重、中尾周、若林繁夫
- Organizer
  第108回　近畿生理談話会
- Place of Presentation
  近畿大学
- Year and Date
  2015-10-24
- Data Source
  KAKENHI-PROJECT-15K08200
[Presentation] Aerobic treadmill training prevents the obesity caused by gene disruption of Ca2+-sensor protein in mice2015
- Author(s)
  Wakabayashi, S., Nakao, S., Inagaki, T., Tsuchimochi, H., Nakamura, T.Y., Shirai, M.
- Organizer
  第92回日本生理学会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2015-03-23
- Data Source
  KAKENHI-PROJECT-26460312
[Presentation] 細胞内カルシウムセンサーによる心筋ストレス防御機構2015
- Author(s)
  西谷（中村）友重、中尾周、若林繁夫
- Organizer
  心血管膜輸送研究会2015
- Place of Presentation
  生理学研究所
- Year and Date
  2015-10-29
- Invited
- Data Source
  KAKENHI-PROJECT-15K08200
[Presentation] 細胞内カルシウムセンサーによる心筋ストレス防御機構2015
- Author(s)
  西谷（中村）友重、中尾周、若林繁夫
- Organizer
  心血管膜輸送研究会2015
- Place of Presentation
  岡崎、生理学研究所
- Year and Date
  2015-10-29
- Data Source
  KAKENHI-PROJECT-26460312
[Presentation] Role of Ca2+ sensor-1 in learning and memory in mice2015
- Author(s)
  Nakao, S., Nakajo, Y., Takahashi, J.C., Nakagawa, O., Wakabayashi, S., Yamamoto, H., and Nakamura-Nishitani, T.Y.
- Organizer
  第92回日本生理学会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PROJECT-26460312
[Presentation] 癌悪液質における筋傷害にCa2+透過チャネルは関与するか？2015
- Author(s)
  岩田裕子、鈴木伸之、若林繁夫
- Organizer
  第1回日本筋学会学術集会
- Place of Presentation
  国立精神・神経医療研究センター
- Year and Date
  2015-07-08
- Data Source
  KAKENHI-PROJECT-26460312
[Presentation] 胞内Ca2+センサー蛋白質を介した心筋内ストレス防御機構2015
- Author(s)
  西谷（中村）友重、中尾周、若林繁夫
- Organizer
  第108回　近畿生理談話会
- Place of Presentation
  近畿大学
- Year and Date
  2015-10-24
- Data Source
  KAKENHI-PROJECT-26460312
[Presentation] 継続的な有酸素運動はCa2+センサー蛋白質欠損で起こるマウスの肥満を解消できる2015
- Author(s)
  若林繁夫、中尾周、稲垣薫克、土持裕胤、中村―西谷友重、白井幹康
- Organizer
  BMB2015　第38回日本分子生物学会年会および第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸国際会議場・展示場
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26460312
[Presentation] 細胞内Ca2+センサーによる新規代謝調節経路2015
- Author(s)
  西谷（中村）友重、中尾周、中川修、若林繁夫
- Organizer
  第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K08200
[Presentation] 継続的な有酸素運動はCa2+センサー蛋白質欠損で起こるマウスの肥満を解消できる2015
- Author(s)
  若林繁夫、中尾周、稲垣薫克、土持裕胤、中村―西谷友重、白井幹康
- Organizer
  第38回日本分子生物学会年会および第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K08200
[Presentation] Absence of TRPV2 impaired BAT thermogenesis in mice.2015
- Author(s)
  Sun, W., Uchida, K., Suzuki, Y., Zhou, Y., Kim, M., Takayama, Y., Takahashi, N., Goto, T., Wakabayashi, S., Kawada, T., Y., and Tominaga, M
- Organizer
  The 5th International Ion Channel Conference
- Place of Presentation
  Luzhou, Sichuan, China
- Year and Date
  2015-06-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460312
[Presentation] Na+/H+交換輸送体NHE1とカルシニューリンとの結合に対するGタンパク質共役型受容体刺激の効果2015
- Author(s)
  久光　隆、若林繁夫、中川　修
- Organizer
  BMB2015　第38回　日本分子生物学会年会　第88回日本生化学会　合同大会
- Place of Presentation
  神戸国際会議場・展示場
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26460312
[Presentation] Calcineurin B homologous protein (CHP3) regulates phosphorylation of GSK3beta2015
- Author(s)
  Kobayashi, S., Wakabayashi, S
- Organizer
  第92回日本生理学会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PROJECT-26460312
[Presentation] Na+/H+交換輸送体NHE1とカルシニュリンとの適度な結合親和性が下流のNFAT転写活性の増幅に重要である2014
- Author(s)
  久光　隆、若林繁夫
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島大学
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] Calcineurin B homologous protein 3 (CHP3)はAkt-GSK3シグナルを調節する2014
- Author(s)
  古林創史、若林繁夫
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-26460312
[Presentation] ATP 結合蛋白質としてのNa^+/H^+交換輸送体NHE1 : 脂質結合ドメインを介する活性制御2014
- Author(s)
  若林繁夫, 嶋田-清水直子, 久光隆, 中村-西谷友重
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島大学
- Year and Date
  2014-03-17
- Invited
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] Regulation of nuclear and cytoplasmic Ca2+ signaling and its function in cardiomyocytes: role of neuronal Ca2+ sensor-12014
- Author(s)
  Tomoe Y. Nakamura-Nishitani, Shu Nakao and Shigeo Wakabayashi
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島（鹿児島）
- Data Source
  KAKENHI-PROJECT-25860174
[Presentation] Na^+/H^+交換輸送体NHE1 とカルシニュリンとの適度な結合親和性が下流のNFAT 転写活性の増幅に重要である2014
- Author(s)
  久光隆, 若林繁夫
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島大学
- Year and Date
  2014-03-16
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] Na^+/H^+交換輸送体NHE1とカルシニュリンとの適度な結合親和性が下流のNFAT転写活性の増幅に重要である2014
- Author(s)
  久光隆、若林繁夫
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島大学
- Data Source
  KAKENHI-PROJECT-23590105
[Presentation] ATP結合蛋白質としてのNa+/H+交換輸送体NHE1：脂質結合ドメインを介する活性制御2014
- Author(s)
  若林繁夫、嶋田-清水直子、久光　隆、中村-西谷友重
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島大学
- Invited
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] ストレス下の心筋におけるサバイバル機構：Ca2+センサーNCS-1の役割2014
- Author(s)
  中村(西谷)友重、中尾　周、若林繁夫
- Organizer
  第5回Molecular Cardiovascular Conference II
- Place of Presentation
  神戸ベイシェラトンホテル＆タワーズ
- Year and Date
  2014-09-05
- Data Source
  KAKENHI-PROJECT-26460312
[Presentation] マウス心筋細胞における核内カルシウム動態の生理的役割：細胞内カルシウム動態との関連について2014
- Author(s)
  中尾　周、若林繁夫、中村(西谷)友重
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-17
- Data Source
  KAKENHI-PROJECT-26460312
[Presentation] 心筋細胞の核内カルシウム濃度調節におけるカルシウムセンサーNCS-1の機能とその局在2014
- Author(s)
  中尾周，中村（西谷）友重，若林繁夫
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島（鹿児島）
- Data Source
  KAKENHI-PROJECT-25860174
[Presentation] Regulation of the cardiac Na^+/H^+ exchanger in health and disease2014
- Author(s)
  Wakabayashi S
- Organizer
  35th Anniversary Symposium "Growth Control Lab"
- Place of Presentation
  Hotel West End Nice/FRANCE
- Year and Date
  2014-03-07
- Invited
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] Regulation of the cardiac Na+/H+ exchanger in health and disease.2014
- Author(s)
  Wakabayashi, S.
- Organizer
  35th Anniversary Symposium “Growth Control Lab
- Place of Presentation
  Hotel West End, Nice, FRANCE
- Invited
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] Na+/H+交換輸送体NHE1とカルシニュリンとの適度な結合親和性が下流のNFAT転写活性の増幅に重要である2014
- Author(s)
  久光　隆、若林繁夫
- Organizer
  第91回　日本生理学会大会
- Place of Presentation
  鹿児島大学
- Data Source
  KAKENHI-PROJECT-23590105
[Presentation] Na+/H+交換輸送体のスフィンゴ脂質による活性化2014
- Author(s)
  若林繁夫、久光　隆、西谷(中村)友重、白井幹康
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-16
- Data Source
  KAKENHI-PROJECT-26460312
[Presentation] マウスの空間学習・記憶におけるカルシウムセンサーNCS-1の役割2014
- Author(s)
  中村(西谷)友重、中尾　周、中城友香子、高橋　淳、若林繁夫、柳本広二
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-16
- Data Source
  KAKENHI-PROJECT-26460312
[Presentation] Na^+/H^+交換輸送体NHE1 とカルシニューリンとの適度な結合親和性が下流のNFAT 活性の増幅効率を決める2013
- Author(s)
  久光隆, 若林繁夫
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2013-09-13
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] 心筋細胞の核内Ca2+濃度調節におけるカルシウムセンサーNCS-1の役割2013
- Author(s)
  中尾周，中村（西谷）友重，若林繁夫
- Organizer
  第106回近畿生理談話会
- Place of Presentation
  橿原（奈良）
- Data Source
  KAKENHI-PROJECT-25860174
[Presentation] Evidence that Na^+/H^+ exchanger 1 is an ATP-binding protein : a possible mechanism for ATP requirement of transport activity2013
- Author(s)
  Shimada-Shimizu N, Hisamitsu T, Nakamura TY, Wakabayashi S
- Organizer
  Nagoya Symposium Frontiers in Structural Physiology
- Place of Presentation
  名古屋大学
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] Na^+/H^+交換輸送体NHE1はカルシニューリンとの結合を介して下流のNFAT活性を増幅する2013
- Author(s)
  久光隆、若林繁夫
- Organizer
  第85会日本薬理学会年会
- Place of Presentation
  京都国際会館
- Data Source
  KAKENHI-PROJECT-23590105
[Presentation] Na^+/H^+交換輸送体NHE1 はその細胞質領域のPVITID 配列に直接結合したカルシニューリンを介して下流のNFAT 活性を増幅する2013
- Author(s)
  久光隆, 若林繁夫
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] 心筋の核内カルシウムシグナル制御におけるカルシウムセンサーNCS-1の役割2013
- Author(s)
  中尾周，中村（西谷）友重，若林繁夫
- Organizer
  第86回日本生化学会
- Place of Presentation
  横浜（神奈川）
- Data Source
  KAKENHI-PROJECT-25860174
[Presentation] Na^+/H^+ exchanger (NHE1)の活性調節は脂質結合ドメインの分子スイッチ機構で起こる : 制御に選択的な薬剤を用いた解析2013
- Author(s)
  若林繁夫, 嶋田-清水直子, 久光隆, 平山令明, 中村(西谷)友重
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2013-09-12
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] Na+/H+交換輸送体NHE1によるカルシニューリンの活性増幅作用には両者の適度な結合親和性が重要である2013
- Author(s)
  久光　隆、若林繁夫
- Organizer
  日本生体エネルギー研究会　第39回討論会
- Place of Presentation
  静岡県コンベンションアーツセンター
- Data Source
  KAKENHI-PROJECT-23590105
[Presentation] Na+/H+ exchanger (NHE1)の活性調節は脂質結合ドメインの分子スイッチ機構で起こる：制御に選択的な薬剤を用いた解析2013
- Author(s)
  若林繁夫、嶋田-清水直子、久光　隆、平山令明、中村(西谷)友重
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] The Na+/H+ exchanger1: signaling pathways leading to cardiac hypertrophy. “Cardiac Ca2+, Na+ and pH regulation in health and disease Kaito Symposium”2013
- Author(s)
  Wakabayashi, S.
- Organizer
  ISHR XXI World Congress
- Place of Presentation
  San Diego Convention Center/USA
- Invited
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] Na+/H+交換輸送体NHE1とカルシニューリンとの適度な結合親和性が下流のNFAT活性の増幅効率を決める2013
- Author(s)
  久光　隆、若林繁夫
- Organizer
  第86回　日本生化学会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590105
[Presentation] Na+/H+ exchanger NHE1 directly binds calcineurin and enhances downstream NFAT transcriptional activity2013
- Author(s)
  Hisamitsu, T., and Wakabayashi, S.
- Organizer
  H+ SSS : H+ ion sensing, signaling and servo-control
- Place of Presentation
  University of OXFORD, UK
- Data Source
  KAKENHI-PROJECT-23590105
[Presentation] Na+/H+ exchanger NHE1 directly binds calcineurin and enhances downstream NFAT transcriptional activity2013
- Author(s)
  Hisamitsu T, Wakabayashi S
- Organizer
  IUPS Satellite Symposium "H^+ Ion Sensing, Signalling and Servo-control"
- Place of Presentation
  University of Oxford/UK
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] Na^+/H^+交換輸送体NHE1 によるカルシニューリンの活性増幅作用には両者の適度な結合親和性が重要である2013
- Author(s)
  久光隆, 若林繁夫
- Organizer
  日本生体エネルギー研究会第39回討論会
- Place of Presentation
  静岡県コンベンションアーツセンター
- Year and Date
  2013-12-19
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] Na^+/H^+ exchanger NHE1 directly binds calcineurin and enhances downstream NFAT transcriptional activity., H^+ SSS : H^+ ion sensing, signaling and servo-control2013
- Author(s)
  Hisamitsu, T., and Wakabayashi, S
- Organizer
  IUPS Satellite Symposium
- Place of Presentation
  Oxford University, UK
- Data Source
  KAKENHI-PROJECT-23590105
[Presentation] 心臓におけるNa^+/H^+交換輸送体の制御と病態的意義2013
- Author(s)
  若林繁夫
- Organizer
  日本生体エネルギー研究会第39回討論会
- Place of Presentation
  静岡県コンベンションアーツセンター
- Year and Date
  2013-12-18
- Invited
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] Na^+/H^+交換輸送体NHE1 によるpH 制御機構 : 心臓肥大に導く上流・下流のシグナル伝達2013
- Author(s)
  若林繁夫
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  タワーホール船堀(東京)
- Year and Date
  2013-03-28
- Invited
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] Na+/H+交換輸送体NHE1によるカルシニューリンの活性増幅作用には両者の適度な結合親和性が重要である2013
- Author(s)
  久光　隆、若林繁夫
- Organizer
  日本生体エネルギー研究会第39回討論会
- Place of Presentation
  静岡県コンベンションアーツセンター
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] Na+/H+ exchanger (NHE1) の活性調節は脂質結合ドメインの分子スイッチ機構で起こる：制御に選択的な薬剤を用いた解析2013
- Author(s)
  若林繁夫、嶋田－清水直子、久光　隆、平山令明、中村（西谷）友重
- Organizer
  第86回　日本生化学会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590105
[Presentation] The Na^+/H^+ exchanger1 : signaling pathways leading to cardiac hypertrophy2013
- Author(s)
  Wakabayashi S
- Organizer
  "Cardiac Ca^<2+>, Na^+ and pH regulation in health and disease Kaito Symposium" ISHR XXI World Congress
- Place of Presentation
  San Diego Convention Center/USA
- Year and Date
  2013-07-03
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] Na+/H+ exchanger NHE1 directly binds calcineurin and enhances downstream NFAT transcriptional activity.2013
- Author(s)
  Hisamitsu, T, Wakabayashi, S.:
- Organizer
  IUPS Satellite Symposium “H+ Ion Sensing, Signalling and Servo-control
- Place of Presentation
  University of Oxford/UK
- Invited
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] Na+/H+交換輸送体NHE1とカルシニューリンとの適度な結合親和性が下流のNFAT活性の増幅効率を決める2013
- Author(s)
  久光　隆、若林繁夫
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] 心臓におけるNa+/H+交換輸送体の制御と病態的意義2013
- Author(s)
  若林繁夫
- Organizer
  日本生体エネルギー研究会第39回討論会
- Place of Presentation
  静岡県コンベンションアーツセンター
- Invited
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] Na^+/H^+交換輸送体NHE1近傍のlocal pHをモニターする蛍光プローブの作成2012
- Author(s)
  若林繁夫
- Organizer
  日本生理学会
- Place of Presentation
  松本市総合体育館(長野県)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] Na^+/H^+交換輸送体NHE1 近傍のlocal pH をモニターする蛍光プローブの作成2012
- Author(s)
  若林繁夫
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  松本市総合体育館
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] Na-/H・交換輸送体NHEl近傍のlocal pHをモニターする蛍光プローブの作成2012
- Author(s)
  若林繁夫
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  松本市総合体育館
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-22659046
[Presentation] Na^+/H^+交換輸送体による心肥大カルシウムシグナルの制御2012
- Author(s)
  若林繁夫
- Organizer
  生体機能と創薬シンポジウム2012
- Place of Presentation
  神戸学院大学
- Year and Date
  2012-08-31
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] Na^+/H^+交換輸送体NHE1は脱リン酸化酵素カルシニューリンと直接結合し、その活性を調節する2012
- Author(s)
  久光隆、若林繁夫
- Organizer
  第7回トランスポーター研究会
- Place of Presentation
  京都大学
- Data Source
  KAKENHI-PROJECT-23590105
[Presentation] Na+/H+交換輸送体NHE1は脱リン酸化酵素カルシニューリンと直接結合し、その活性を調節する2012
- Author(s)
  久光　隆、若林繁夫
- Organizer
  第7回トランスポーター研究会
- Place of Presentation
  京都大学
- Data Source
  KAKENHI-PROJECT-23590105
[Presentation] Na+/H+交換輸送体NHE1によるCaN活性増幅機構の解析2012
- Author(s)
  久光　隆、若林繁夫
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23590105
[Presentation] Na^+/H^+交換輸送体NHE1 の活性調節をブロックする阻害剤の活性-構造相関2012
- Author(s)
  嶋田-清水直子, 久光隆, 平山令明, 若林繁夫
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] Na+/H+交換輸送体NHE1とカルシニューリンとの直接結合を介する新しい心肥大シグナル増強経路2012
- Author(s)
  久光　隆、西谷友重、若林繁夫
- Organizer
  第105会近畿生理学談話会
- Place of Presentation
  関西医科大学
- Data Source
  KAKENHI-PROJECT-23590105
[Presentation] カルシニューリンB様蛋白質CHP3 によるGSK3βの活性調節メカニズムの解明2012
- Author(s)
  古林創史, 若林繁夫
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] Na^+/H^+交換輸送体によるカルシニューリン-NFAT シグナル増幅 : 結合モチーフPVITID 配列の変異解析2012
- Author(s)
  久光隆, 若林繁夫
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] Na^+/H^+交換輸送体NHE1近傍のlocal pHをモニターする蛍光プローブの作成2012
- Author(s)
  若林繁夫
- Organizer
  日本生理学会
- Place of Presentation
  松本市総合体育館(長野県)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-22659046
[Presentation] Na^+/H^+交換輸送体による心肥大カルシウムシグナルの制御2012
- Author(s)
  若林繁夫
- Organizer
  生体機能と創薬シンポジウム2012
- Place of Presentation
  神戸学院大学
- Year and Date
  2012-08-31
- Data Source
  KAKENHI-PROJECT-22659046
[Presentation] Na^+/H^+交換輸送体の活性調節における生理活性脂質の役割2011
- Author(s)
  若林繁夫他
- Organizer
  第88回日本生理学会大会
- Place of Presentation
  パシフイコ横浜
- Year and Date
  2011-03-28
- Data Source
  KAKENHI-PROJECT-22659046
[Presentation] Na^+/H^+交換輸送体の生理活性調節における生理活性脂質の役割2011
- Author(s)
  若林繁夫, 他
- Organizer
  第88回日本生理学会大会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-03-28
- Data Source
  KAKENHI-PLANNED-18077015
[Presentation] Na^+/H^+交換輸送体(NHE1)の活性化による心肥大シグナル増幅機構2011
- Author(s)
  久光隆, 中村(西谷)友重, 古林創史, 嶋田直子, 岩田裕子, 若林繁夫
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都国際会議場
- Year and Date
  2011-09-21
- Invited
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] Na^+/H^+交換輸送体(NHE1)の活性化による心肥大シグナル増幅機構2011
- Author(s)
  久光隆、中村(西谷)友重、古林創史、嶋田直子、岩田裕子、○若林繁夫
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都国際会館
- Data Source
  KAKENHI-PROJECT-23590105
[Presentation] Na^+/H^+交換輸送体の生理活性調節における生理活性脂質の役割2011
- Author(s)
  若林繁夫, 他
- Organizer
  第88回日本生理学会大会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-03-28
- Data Source
  KAKENHI-PROJECT-22659046
[Presentation] カルシウムセンサーNCS-1は心筋カルシウムシグナルを増強して幼若心筋の心機能亢進および心肥大に寄与する2011
- Author(s)
  中村(西谷)友重、アンドレス・ジェロミン、御子柴克彦、若林繁夫
- Organizer
  第88回日本生理学会大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PLANNED-18077015
[Presentation] Molecular mechanism for hormonal activation of the Na^+/H^+ exchanger (NHE1) and its consequence in cardiac hypertrophy and heart failure. (Symposium "Sodium homeostasis and cardiac function")ISHR2010
- Author(s)
  Wakabayashi, S.
- Organizer
  第20回世界会議
- Place of Presentation
  京都国際会議場
- Year and Date
  2010-05-13
- Data Source
  KAKENHI-PLANNED-18077015
[Presentation] Na^+/H^+交換輸送体は生理活性脂質およびホルボールエステルとの直接的相互作用を介して活性化される2010
- Author(s)
  若林繁夫, 他
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡市民文化ホール(岩手県)
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PLANNED-18077015
[Presentation] Newly identified phorbol ester-binding motif mediates hormonal activation of Na+/H+ exchanger (NHE1).2010
- Author(s)
  Wakabayashi, S., et al.
- Organizer
  第83回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22659046
[Presentation] 心筋症モデル動物におけるCa^<2+>透過チャネルTRPV2の活性阻害は筋変性を軽減する2010
- Author(s)
  岩田裕子、若林繁夫
- Organizer
  日本薬理学会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-19390080
[Presentation] Molecular mechanism for hormonal activation of the Na^+/H^+ exchanger (NHE1) and its consequence in cardiac hypertrophy and heart failure.2010
- Author(s)
  Wakabayashi, S.
- Organizer
  国際心臓研究学会第20回世界会議
- Place of Presentation
  京都国際会議場(京都府)
- Year and Date
  2010-05-13
- Data Source
  KAKENHI-PLANNED-18077015
[Presentation] Newly identified phorbol ester-binding motif mediates hormonal activation of Na^+/H^+ exchanger (NHE1).2010
- Author(s)
  Wakabayashi, S., Nakamura-Nishitani, Y., Kobayashi, S., Hisamitsu, T.
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PLANNED-18077015
[Presentation] Na^+/H^+交換輸送体は生理活性脂質およびホルボールエステルとの直接的相互作用を介して活性化される2010
- Author(s)
  若林繁夫, 他
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡市民文化ホール(岩手県)
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-22659046
[Presentation] Na^+/H^+交換輸送体は生理活性脂質およびホルボールエステルとの直接的相互作用を介して活性化される2010
- Author(s)
  若林繁夫他
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡市民文化ホール
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-22659046
[Presentation] Molecular mechanism for hormonal activation of the Na^+/H^+ exchanger (NHE1) and its consequence in cardiac hypertrophy and heart failure.2010
- Author(s)
  Wakabayashi, S.
- Organizer
  国際心臓研究学会第20回世界会議
- Place of Presentation
  京都国際会議場(京都府)
- Year and Date
  2010-05-13
- Data Source
  KAKENHI-PROJECT-22659046
[Presentation] Newly identified phorbol ester-binding motif mediates hormonal activation of Na^+/H^+ exchanger (NHE1).2010
- Author(s)
  Wakabayashi, S., et al.
- Organizer
  第83回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PLANNED-18077015
[Presentation] Na^+/H^+交換輸送体の脂質センサーを介する活性調節2010
- Author(s)
  若林繁夫
- Organizer
  特定流域研究公開シンポジウム
- Place of Presentation
  東京大学弥生講堂(東京都)
- Year and Date
  2010-12-23
- Data Source
  KAKENHI-PLANNED-18077015
[Presentation] Neuroanal Ca2^+ Sensor-1 (NCS-1)の心筋Ca^<2+>シグナル調節因子としての機能解析2009
- Author(s)
  中村(西谷)友重、若林繁夫
- Organizer
  日本生化学会
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PLANNED-18077015
[Presentation] 心筋細胞におけるCa^<2+>結合蛋白質CHP3の生理機能の解析2009
- Author(s)
  古林創史、若林繁夫
- Organizer
  日本生化学会
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-19390080
[Presentation] N^+/H^+交換輸送体(NHE1)の生理活性脂質による活性調節2009
- Author(s)
  若林繁夫、中村(西谷)友重、久光隆
- Organizer
  日本生化学会
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PLANNED-18077015
[Presentation] 拡張型心筋症発症におけるCa^<2+>透過チャネルTRPV2の病態的役割2009
- Author(s)
  岩田裕子、若林繁夫
- Organizer
  日本生化学会
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-19390080
[Presentation] Ca^<2+>透過チャネルTRPV2阻害による筋変性疾患最善効果2009
- Author(s)
  岩田裕子、若林繁夫
- Organizer
  TRPチャネル研究会
- Place of Presentation
  岡崎カンファレンスセンター
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-19390080
[Presentation] Amelioration of muscular dystrophy by dominant-negative inhibition of Ca2+ influx via TRPV22009
- Author(s)
  Iwata, Y., Wakabayashi, S
- Organizer
  第36回国際生理学会
- Place of Presentation
  京都国際会議場
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-19390080
[Presentation] Amelioration of muscular dystrophy by dominant-negative inhibition of Ca^<2+> influx via TRPV22009
- Author(s)
  Iwata,Y., Wakabayashi,S.
- Organizer
  国際生理学会
- Place of Presentation
  京都国際会議場
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-19390080
[Presentation] Ca^<2+>-permeable channel TRPV2 as a promising therapeutic target for muscular dystrophy2009
- Author(s)
  Iwata,Y., Wakabayashi,S.
- Organizer
  日仏筋ジストロフィーシンポジウム
- Place of Presentation
  パリ、心筋研究所
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-19390080
[Presentation] 細胞内Ca^<2+>センサーNCS-1の心臓における新規機能の解析2008
- Author(s)
  西谷友重・若林繁夫
- Organizer
  特定領域研究「細胞感覚」平成20年度冬の班会議
- Place of Presentation
  岡崎カンファレンスセンター
- Data Source
  KAKENHI-PROJECT-19590220
[Presentation] 新しい心機能調節因子としてのCa^<2+>センサータンパク質NCS-1の役割2008
- Author(s)
  中村(西谷)友重, Jeromin, A., 若林繁夫
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19590220
[Presentation] 新しい心機能調節因子としてのCa^<2+>センサータンパク質NCS-1の役割2008
- Author(s)
  中村(西谷)友重・Jeromin, A.・若林繁夫
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19590220
[Presentation] 新しい心機能調節因子としてのCa^<2+>センサータンパク質NCS-1の役割2008
- Author(s)
  中村(西谷)友重、Jeromin, A., 若林繁夫
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PLANNED-18077015
[Presentation] Na+/H+交換輸送体の活性化は心肥大・心不全を引き起こす:細胞内イオン代謝と分子機構の解析2008
- Author(s)
  中村(西谷)友重、岩田裕子、若林繁夫
- Organizer
  第85回日本生理学会大会
- Place of Presentation
  京王プラザホテル東京
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19390080
[Presentation] SF9細胞からのNa^+/H^+交換輸送体/CHP複合体の発現と精製2008
- Author(s)
  若林繁夫, 他
- Organizer
  日本生化学会
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19390080
[Presentation] SF9細胞からのNa^+/H^+交換輸送体/CHP複合体の発現と精製2008
- Author(s)
  若林繁夫, 他
- Organizer
  日本生化学会
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PLANNED-18077015
[Presentation] Structural and functional aspects of the Na^+/H^+ exchanger 1 and its obligatory binding partner CHP.2007
- Author(s)
  Wakabayashi, S.
- Organizer
  Experimental Biology Annual Meeting 2007
- Place of Presentation
  Washington, DC, USA
- Data Source
  KAKENHI-PLANNED-18077015
[Presentation] Structural and functional aspects of the Na^+/H^+ exchanger l and its obliatory binding partner CHP.2007
- Author(s)
  Wakabayashi, S.
- Organizer
  Experimental Biology Annual Meeting
- Place of Presentation
  Washington,DC,USA
- Data Source
  KAKENHI-PLANNED-18077015
[Presentation] Na^+/H^+ exchange inhibitors protect against muscle degerneration in cardiomyopathic hamsters.2006
- Author(s)
  Iwata, Y., Katanosaka, Y., Wakabayashi, S.
- Organizer
  26^<th> Annual Scientific Sessions, European Section of the ISHR
- Place of Presentation
  Univ. of Manchester, UK
- Data Source
  KAKENHI-PLANNED-18077015
[Presentation] Novel roles of NCS-1, a calcium sensor protein, on neuronal survival and cardiac excitability.2006
- Author(s)
  Nakamura, T., Jeromin, A., Nabekura, J., Wakabayashi, S.
- Organizer
  20^<th> IUBMB International Congress of Biochemistry and Molecular Biology and 11^<th> FAOBMB congress
- Place of Presentation
  Kyoto Japan
- Data Source
  KAKENHI-PLANNED-18077015
[Presentation] Na^+/H^+ exchange inhibitors protect against muscle degerneration in cardiomyopathic hamsters. 26th Annual Scientific Sessions2006
- Author(s)
  Iwata, Y., Katanosaka, Y., Wakabayashi, S.
- Organizer
  European Section of the ISHR
- Place of Presentation
  Univ. of Manchester, UK
- Data Source
  KAKENHI-PLANNED-18077015
[Presentation] Na+/H+交換輸送体による心肥大カルシウムシグナルの制御
- Author(s)
  若林繁夫
- Organizer
  生体機能と創薬シンポジウム2012
- Place of Presentation
  神戸学院大学
- Invited
- Data Source
  KAKENHI-PROJECT-22659046
[Presentation] マウス心筋細胞における核内Ca2+動態の生理的役割―細胞質内Ca2+動態との関連について―
- Author(s)
  中尾周，若林繁夫，中村（西谷）友重
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25860174
[Presentation] Na+/H+交換輸送体NHE1はカルシニューリンとの直接結合を介して下流のNFAT経路を活性化する
- Author(s)
  ○久光　隆、若林繁夫
- Organizer
  第８９回日本生理学会大会
- Place of Presentation
  長野県松本文化会館
- Data Source
  KAKENHI-PROJECT-23590105
[Presentation] Na+/H+交換輸送体による心肥大カルシウムシグナルの制御
- Author(s)
  若林繁夫
- Organizer
  生体機能と創薬シンポジウム2012
- Place of Presentation
  神戸学院大学
- Data Source
  KAKENHI-PROJECT-23390046
[Presentation] Na+/H+交換輸送体(NHE1)の活性化による心肥大シグナル増幅機構
- Author(s)
  久光　隆、中村(西谷）友重、古林創史、嶋田直子、岩田裕子、○若林繁夫
- Organizer
  第８４回日本生化学会大会(招待講演)
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23590105
[Presentation] Na+/H+交換輸送体NHE1はカルシニューリンとの結合を介して下流のNFAT活性を増幅する
- Author(s)
  ○久光　隆、若林繁夫
- Organizer
  第８５回日本薬理学会年会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23590105
[Presentation] Na+/H+交換輸送体NHE1はATP結合トランスポータか？
- Author(s)
  ○嶋田直子、久光　隆、若林繁夫
- Organizer
  第８４回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23590105
[Presentation] Na+/H+交換輸送体NHE1近傍のlocal pHをモニターする蛍光プローブの作成
- Author(s)
  ○若林繁夫、久光　隆
- Organizer
  第８９回日本生理学会大会
- Place of Presentation
  長野県松本文化会館
- Data Source
  KAKENHI-PROJECT-23590105

1. NISHITANI Tomoe (50393244)

# of Collaborated Projects: 10 results

# of Collaborated Products: 72 results
2. SHIGEKAWA Munekazu (00113738)

# of Collaborated Projects: 10 results

# of Collaborated Products: 22 results
3. IWAMOTO Takahiro (20300973)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
4. HISAMITSU Takashi (50327946)

# of Collaborated Projects: 7 results

# of Collaborated Products: 69 results
5. IKEDA Toshitaro

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
6. IWATA Yuko (80171908)

# of Collaborated Projects: 5 results

# of Collaborated Products: 43 results
7. KOBAYASHI SOUSHI (50511531)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
8. SHIMADA Naoko (60600385)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
9. NAKAO Shu (30646956)

# of Collaborated Projects: 3 results

# of Collaborated Products: 17 results
10. YOUSSEF Ben Ammar (90463273)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
11. Jin Meihua (40746773)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
12. OGURUSU Taro (70177202)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. TOMINAGA Makoto (90260041)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. TAKEDA Souichi (80332279)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. KAMAUCHI Shinya (00397564)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. Shirai Mikiyasu (70162758)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
17. 岡田泰伸 (10025661)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 鍋倉淳一 (50237583)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 東原和成 (00280925)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 上田陽一 (10232745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 渡辺公英 (00093485)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 中川修 (40283593)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
23. KOBAYASHI Yoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. KAWAKAMI Haruka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. パンテンシャン

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. WATANABE Takahide

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. ITO Yuri

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. MATSUI Hiroki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. KURABAYASHI MASAHIKO

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. HARAGUCHI Tokuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. SAKAI Fumie

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. HASHIMOTO Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. SHIMIZU Chigusa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. HAYAKAWA Tomoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 内田邦敏

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
36. 高山靖規

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 河原克雅

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 森原啓文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 藤阪保仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 須永浩章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 大隅隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 柳瀬敏彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 野村政壽

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 高山千利

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. 松下正之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 近藤毅

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. 橋本有弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

WAKABAYASHI Shigeo 若林 繁夫

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Analysis of novel genes involved in cardiac function using iPSC-derived cardiomyocytesPrincipal Investigator

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Amplification of intracellular signaling initiated near the plasma membrane transportersPrincipal Investigator

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Molecular mechanism for regulaiton of ion transporter via lipid signaling and its structural basisPrincipal Investigator

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Molecular mechanism for regulation of ion transporter and channel by bioactive I ipidsPrincipal Investigator

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Pathological roles of ion transporter/channel as therapeutic targets in muscle degenerative diseasePrincipal Investigator

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Na+/H+アンチポータの機能制御複合体を構成する新規タンパク質の探索Principal Investigator

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Regulatory mechanism for interaction between membrane proton sensor and cytosolic ion sensor.Principal Investigator

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ストレッチ感受性Ca^<2+>チャネルを標的にした筋変性疾患治療薬物の開発Principal Investigator

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WAKABAYASHI Shigeo 若林繁夫