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Shiro Yoshitsugu  城 宜嗣

ORCIDConnect your ORCID iD *help
… Alternative Names

SHIRO Yoshitsugu  城 宜嗣

城 宣嗣  シロ ヨシツグ

城 宜嗣  シロ ヨシツグ

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Researcher Number 70183051
Other IDs
External Links
Affiliation (Current) 2025: 兵庫県立大学, 理学研究科, 特任教授
Affiliation (based on the past Project Information) *help 2022 – 2023: 兵庫県立大学, 理学研究科, 特任教授
2021 – 2022: 兵庫県立大学, 理学研究科, 特命教授
2021: 兵庫県立大学, 理学研究科, 教授
2016 – 2020: 兵庫県立大学, 生命理学研究科, 教授
2017: 兵庫県立大学, 大学院生命理学研究科, 教授 … More
2015 – 2016: 国立研究開発法人理化学研究所, 放射光科学総合研究センター, 主任研究員
2015: 国立研究開発法人, 理化学研究所, 主任研究員
2014: 独立行政法人理化学研究所, その他部局等, その他
2013 – 2014: 独立行政法人理化学研究所, 放射光科学総合研究センター, 主任研究員
2004 – 2012: RIKEN, Biometal Science Lab., Chief Scientist, 城生体金属科学研究室, 主任研究員
2007: The Institute of Physical and Chemical Research, 城生体金属科学研究室, 主任研究員
2003: 独立行政法人理化学研究所, 生体物理化学研究室, 主任研究員
2000 – 2002: 理化学研究所, 生体物理化学研究室, 主任研究員
2000 – 2001: 理化学研究所, 生体物理化学研究室, 主任
1999: 京都大学, 理化学研究所, 副主任研究員
1996 – 1998: 理化学研究所, 副主任 研究員
1995: 理化学研究所, バイオデザイン研究グループ生体物理化学研究室, 副主任研究員
1994: 理化学研究所, バイオデサイン研究グループ, 副主任研究員
1993: 理化学研究所, バイオデザイン研究グループ, 副主任研究員
1988: The Institute of Physical and Chemical Research, 生体物理化学研究室, 研究員 Less
Review Section/Research Field
Principal Investigator
Bio-related chemistry / Science and Engineering / Medium-sized Section 37:Biomolecular chemistry and related fields / Complex systems / Bioorganic chemistry / Biophysics / Science and Engineering / Chemistry related to living body / Biological Sciences
Except Principal Investigator
Living organism molecular science … More / Biological Sciences / Complex systems / Physical chemistry / Science and Engineering / 生物物性学 / Structural biochemistry Less
Keywords
Principal Investigator
一酸化窒素 / 脱窒 / 一酸化窒素還元酵素 / X線結晶構造解析 / 温室効果ガス / 亜酸化窒素 / ヘム鉄 / ヘム酵素 / 金属酵素 / 分子進化 … More / 呼吸酵素 / 構造ダイナミクス / 二成分情報伝達系 / センサータンパク質 / センサー蛋白質 / XAFS / ヒスチジンキナーゼ / 嫌気呼吸 / 非ヘム鉄 / チトクロム酸化酵素 / オゾン層破壊 / キヌレニン経路 / トリプトファン代謝 / 二原子酸素添加酵素 / チトクロムP450 / 時間分解分光解析 / 時間分解解析 / 緑膿菌 / ナノディスク複合体 / クライオ電子顕微鏡 / 時間分解構造解析 / 低温電子顕微鏡 / 髄膜炎菌 / 抗菌剤開発 / 呼吸酵素の分子進化 / 抗菌ガス / 鉄センサー / 構造解析 / 鉄含有酵素 / 鉄トランスポーター / タンパク質複合体 / 構造機能解析 / フェリチン / 鉄含有タンパク質 / 鉄センサータンパク質 / 鉄還元酵素 / トランスポーター / 鉄動態 / 生体鉄 / coordination Chemistry / Metal-enzymes / Signal Transduction / Bio-synthesis / Metalloproteins / エチレンセンサー蛋白質 / 酵素センサー蛋白質 / 金属配位空間 / 感染症 / 老人性白内障 / ヘム / 配位構造 / 配位化学 / 情報変換 / 金属蛋白質 / 物質変換 / X-ray Crystallography / Oxygenation / Heme-enzymes / Hydrogen Peroxide / Hydroxylation of Fatty Acids / Cytochrome P450 / 脂肪酸 / 反応機構 / モノオキシゲナーゼ / ペルオキシダーゼ / ペルオキシゲナーゼ / シトクロムP450 / 酸素添加反応 / 過酸化水素 / 脂肪酸水酸化 / Sensor Protein / Copper (I) complex / Histidine kinase / Two-component system / Plant Hormone / Ethylene / 銅 / リン酸移転 / エチレン受容体 / 銅(I)錯体 / 二成分系 / 植物ホルモン / エチレン / 細胞内タンパク質複合体 / オゾン層破壊物質 / 脱窒菌 / 環境科学 / 窒素循環 / 酵素反応 / 膜タンパク質 / 電子移動反応 / N-N結合生成 / 複核反応中心 / 酵素機能変換 / 人工酵素系 / 人工触媒 / 酸素添加酵素 / 共鳴ラマン分光 / インドールアミン / 酸素分子 / 高分解能結晶構造解析 / 水和電子 / X線還元 / 窒素還元酵素 / SPring-8 / 低温還元法 / 反応中間体 / P450 … More
Except Principal Investigator
ヘム / XANES / EXAFS / 分子進化 / 呼吸 / チトクロムP450 / 動的構造解析 / 生体内金属動態 / 有害金属 / 生命金属 / 金属細胞生物学 / 生物無機化学 / 生命金属科学 / マイクロデバイス / 蛍光寿命測定 / 可視吸収分光法 / 赤外吸収分光法 / タンパク質ダイナミクス / 膜タンパク質 / 分光法 / 時間分解測定 / マイクロ流体デバイス / ダイナミクス / 顕微分光測定 / ABCトランスポーター / 時間分解計測 / 赤外分光法 / X線自由電子レーザー / 顕微分光 / マイクロ流路デバイス / 時間分解分光法 / 直截的分子変換 / 反応場 / 反応活性種 / 結合活性化 / 分子活性化 / 直截分子変換 / Cytochrome P450 / Peroxidase / Hemoglobin / Myoglobin / Laser-Photolysis / Time-Resolved EXAFS / X線吸収スペクトル;ヘモグロビン / 螢光X線 / ミオグロビンCO錯体 / レーザーフォトリシス / 放射光 / 生体高分子の動的構造解析 / フラッシュフォトリシス / ヘム蛋白質 / ペルオキシダーゼ / ヘモグロビン / ミオグロビン / レーザフォトリシス / 時間分解EXAFS / intermediate of enzyme reaction / resonance Raman spectra / X-ray crystal structure / heme / heme oxygenase / 一酸化炭素 / 共鳴ラマンスペクトル / 結晶化 / 酵素反応中間体 / 共鳴ラマン / X線結晶構造解析 / ヘムオキシゲナーゼ / ガス状シグナル分子 / 酸素化型ヘム / alky1 isocyanide / 一酸化窒素(NO) / YC-1 / 5配位高スピン型 / アジド / ヘム鉄 / 低分子シグナル分子 / ヌクレオチド / 可溶性グアニル酸シクラーゼ / 活性発現の分子機構 / 結晶構造 / 呼吸酵素 / 窒素循環 / 反応機構 / 脱窒 / 反応中間体 / 標的分子 / 結晶構造解析 / 低分子化合物 / ライブラリー / 化合物アレイ / リガンド / 受容体 / 相互作用 / 蛋白質 / バイオプローブ / 構造生物学 / 化学生物学 / プロテインキナーゼ / 情報伝達系 / 酸素セレサー / タンパク質リン酸化 / ヒスチジンキナーゼ / 2成分情報伝達系 / 遺伝子発現 / 環境 / 根粒菌 / ヘム輸送 / 酸素適応 / 二成分情報伝達系 / リン酸化 / 酸素センサー / 亜硫酸還元酵素 / モジュール置換 / 金属蛋白質 / フェレドキシン / ペルオキシターゼ / 可視過渡吸収 / タンパク質結晶構造解析 / 時分割 / タンパク質結晶 / 結晶内反応モニター / 時間分割蛋白質結晶構造解析 Less
  • Research Projects

    (26 results)
  • Research Products

    (420 results)
  • Co-Researchers

    (78 People)
  •  Integrated Biometal Science: Research to Explore Dynamics of Metals in Cellular System

    • Principal Investigator
      Tsumoto Kouhei
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      The University of Tokyo
  •  Strctural and Functional Dynamics on Proteins Related to Biometal DynamicsPrincipal Investigator

    • Principal Investigator
      SHIRO Yoshitsugu
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      University of Hyogo
  •  Structural Dynamics of Nitric Oxide Reductases Srudied by Time-Resolved TechniquesPrincipal Investigator

    • Principal Investigator
      Shiro Yoshitsugu
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 37:Biomolecular chemistry and related fields
    • Research Institution
      University of Hyogo
  •  Development of time-resolved spectroscopic systems with micro-flow devices and their application to the molecular mechanism of ABC transporters

    • Principal Investigator
      KIMURA TETSUNARI
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Physical chemistry
    • Research Institution
      Kobe University
  •  Molecular Science of NO Dyanmics in Biological SystemPrincipal Investigator

    • Principal Investigator
      Shiro Yoshitsugu
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Bio-related chemistry
    • Research Institution
      University of Hyogo
      Institute of Physical and Chemical Research
  •  一酸化窒素還元酵素の構造ダイナミクスを基軸とする生命・環境科学への展開Principal Investigator

    • Principal Investigator
      城 宜嗣
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Bio-related chemistry
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Regulation of nitrous oxide formation in cellPrincipal Investigator

    • Principal Investigator
      Yoshitsugu Shiro
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Bio-related chemistry
    • Research Institution
      Institute of Physical and Chemical Research
  •  Regulation of High Specificity and Function of Biological Reaction SpherePrincipal Investigator

    • Principal Investigator
      SHIRO Yoshitsugu
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Development of New Catalytic Reactions Directed to Straightforward Synthesis

    • Principal Investigator
      CHATANI Naoto
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      Osaka University
  •  Molecular Evolution of Respiratory Enzymes; Functional Conversion from NO Reduction to O2 ReductionPrincipal Investigator

    • Principal Investigator
      SHIRO Yoshitsugu
    • Project Period (FY)
      2009 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Chemistry related to living body
    • Research Institution
      The Institute of Physical and Chemical Research
  •  時間分割共鳴ラマン分光法による二原子酸素添加酵素の構造ダイナミクスPrincipal Investigator

    • Principal Investigator
      城 宜嗣
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Crystallographic Studies on the Short-lived Respiratory Enzyme-Substrate Complex

    • Principal Investigator
      NAGANO Shingo
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Signal discrimination analyses based on the domain structure of soluble guanylate cyclase

    • Principal Investigator
      MAKINO Ryu
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Living organism molecular science
    • Research Institution
      Rikkyo University
  •  膜貫通型一酸化窒素還元酵素の一酸化窒素複合体の振動分光学的解析

    • Principal Investigator
      NAGANO Shingo
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Chemical proteomics to reveal interaction between chemicals and proteins at angstrom level

    • Principal Investigator
      OSADA Hiroyuki
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Creative Scientific Research
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Bio-conversion of Substances and Information by Metal-containing Proteins and EnzymesPrincipal Investigator

    • Principal Investigator
      SHIRO Yoshitsugu
    • Project Period (FY)
      2004 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Peroxygenase P450 as a Novel Bio-materialPrincipal Investigator

    • Principal Investigator
      SHIRO Yoshitsugu, 松永 勇
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bioorganic chemistry
    • Research Institution
      RIKEN
      Osaka City University
  •  一酸化窒素還元酵素の反応中間体の高分解能結晶構造解析Principal Investigator

    • Principal Investigator
      城 宜嗣
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  ヘム結合型酸素センサーキナーゼの酸素センシングとリン酸化シグナリングの分子機構

    • Principal Investigator
      NAKAMURA Hiro
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Structure and Function of heme related proteins involved in intracellular signal transduction

    • Principal Investigator
      IKEDA-SAITO Masao
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      TOHOKU UNIVERSITY
  •  Structural Analysis of Ethylene (Plant Hormone) Sensor ProteinPrincipal Investigator

    • Principal Investigator
      SHIRO Yoshitsugu
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biophysics
    • Research Institution
      The Institute of Physical and Chemical Research
  •  生体金属による小分子の活性化

    • Principal Investigator
      森島 績
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyoto University
  •  レーザー光をトリガーとした時間分割蛋白質結晶構造解析システムの性能評価

    • Principal Investigator
      足立 伸一
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The Institute of Physical and Chemical Research
  •  蛋白質結晶内反応を可視吸収変化により追跡するシステムの性能評価

    • Principal Investigator
      足立 伸一
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The Institute of Physical and Chemical Research
  •  蛋白質結晶内反応を可視吸収変化により追跡するシステムの性能評価

    • Principal Investigator
      足立 伸一
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Time-resolved EXAFS method for analyses of dynamical structure of biopolymers

    • Principal Investigator
      IIZUKA Tetsutaro
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      生物物性学
    • Research Institution
      The Institute of Physicaland Chemical Research

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent

  • [Book] ヘムタンパク質の科学2022

    • Author(s)
      城 宜嗣、青野 重利、齋藤 正男
    • Total Pages
      472
    • Publisher
      エヌ・ティー・エス
    • ISBN
      9784860437787
    • Data Source
      KAKENHI-PROJECT-19H00926
  • [Book] ヘムタンパク質の科学2022

    • Author(s)
      城 宜嗣、青野 重利、齋藤 正男
    • Total Pages
      472
    • Publisher
      エヌ・ティー・エス
    • ISBN
      9784860437787
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Book] 生命金属ダイナミクス 生体内における金属の挙動と制御2021

    • Author(s)
      城 宜嗣・津本浩平
    • Total Pages
      511
    • Publisher
      NTS
    • ISBN
      9784860437060
    • Data Source
      KAKENHI-PROJECT-19H00926
  • [Book] 生命金属ダイナミクス 生体内における金属の挙動と制御2021

    • Author(s)
      城 宜嗣・津本浩平
    • Total Pages
      511
    • Publisher
      NTS
    • ISBN
      9784860437060
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Book] RSC Metallobiology Series No. 13, Dioxygen-dependent Heme Enzymes2018

    • Author(s)
      T. Tosha, Y. Shiro
    • Total Pages
      375
    • Publisher
      The Royal Society of Chemistry
    • ISBN
      9781782629917
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Book] Metalloenzymes in Denitrification2017

    • Author(s)
      T. Tosha, Y. Shiro
    • Total Pages
      452
    • Publisher
      Royal Society of Chemistry Metallobiology Series
    • Data Source
      KAKENHI-PROJECT-26620140
  • [Book] Gas Sensing in Cells2017

    • Author(s)
      H. Sawai, Y. Shiro
    • Total Pages
      302
    • Publisher
      The Royal Society of Chemistry Metals in Biology
    • ISBN
      9781782628958
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Book] Metalloenzymes in Denitrification2017

    • Author(s)
      T. Tosha, Y. Shiro
    • Total Pages
      452
    • Publisher
      Royal Society of Chemistry Metallobiology Series
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Book] 鉄の事典2014

    • Author(s)
      藤井 浩、城 宜嗣
    • Total Pages
      820
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Book] 鉄の事典2014

    • Author(s)
      藤井 浩、城 宜嗣
    • Total Pages
      820
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PROJECT-26620140
  • [Book] 鉄の事典2014

    • Author(s)
      藤井 浩、城 宜嗣
    • Total Pages
      820
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Book] in Handbook of Porphyrin Science (K. M. Kadish, K. M. Smith, R. Guilard, Eds.) Vol. 5, Chapter 242011

    • Author(s)
      H. Sugimoto, O. Takikawa, Y. Shiro
    • Publisher
      Tryptophan Catabolism by Heme Dioxygenases
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Book] HandbookofPorphyrinScience, Kadish,K.,Smith,K.,Guilard,R.Eds. Vol.V,Chapter25. World Scientific.(著書)2010

    • Author(s)
      Shiro,y., Nagano,s.
    • Publisher
      No Chemistry by Heme Enzymes
    • Data Source
      KAKENHI-PROJECT-19310147
  • [Book] Handbook of Porphyrin Science (K.M.Kadish, K.M.Smith, R.Guilard, Eds.) Vol.5, Chapter 252010

    • Author(s)
      Y.Shiro, S.Nagano
    • Publisher
      World Scientific
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Book] Handbook of Porphyrin Science (K.M.Kadish, K.M.Smith, R.Guilard, Eds.) Vol.5, Chapter 242010

    • Author(s)
      H.Sugimoto, O.Takikawa, Y.Shiro
    • Publisher
      World Scientific
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Book] in Handbook of Porphyrin Science (K. M. Kadish, K. M. Smith, R. Guilard, Eds.) Vol. 5, Chapter 252010

    • Author(s)
      Y. Shiro, S. Nagano
    • Publisher
      NO Chemistry by Heme-Enzyme
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Book] Handbook of Porphyrin Science (K.M.Kadish, K.M.Smith, R.Guilard, Eds.) Vol.5, Chapter 242010

    • Author(s)
      H.Sugimoto, O.Takikawa, Y.Shiro
    • Publisher
      World Scientific
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Book] Handbook of Porphyrin Science (K.M.Kadish, K.M.Smith, R.Guilard, Eds.) Vol.5, Chapter 252010

    • Author(s)
      Y.Shiro, S.Nagano
    • Publisher
      World Scientific
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Book] Handbook of Porphyrin Science2010

    • Author(s)
      Yoshitsugu Shiro
    • Publisher
      World Scientific
    • Data Source
      KAKENHI-PROJECT-19310147
  • [Book] いま、注目を集めるヘム鉄2009

    • Author(s)
      原田慈久、辛埴、城宜嗣
    • Publisher
      科学11(岩波書店)
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Book] P450の分子構造:X線結晶構造解析を中心に(著書P450の分子生物学第二版)2009

    • Author(s)
      永野真吾、杉本宏、城宜嗣
    • Publisher
      講談社サイエンティフィク
    • Data Source
      KAKENHI-PROJECT-19310147
  • [Book] Bcaterial Signal Transduction : Networks and Drug Targets2008

    • Author(s)
      S.Yamada, Y.Shiro
    • Total Pages
      242
    • Publisher
      Springer Science, Landes Bioscience
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Book] 金属酵素の反応中間体の電子状態・構造解析2008

    • Author(s)
      城宜嗣、藤井浩
    • Publisher
      固体物理11
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Journal Article] Trapping of a Mononitrosyl Nonheme Intermediate of Nitric Oxide Reductase by Cryo-Photolysis of Caged Nitric Oxide2023

    • Author(s)
      Takeda Hanae、Shimba Kanji、Horitani Masaki、Kimura Tetsunari、Nomura Takashi、Kubo Minoru、Shiro Yoshitsugu、Tosha Takehiko
    • Journal Title

      The Journal of Physical Chemistry B

      Volume: 127 Issue: 4 Pages: 846-854

    • DOI

      10.1021/acs.jpcb.2c05852

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K18937, KAKENHI-PROJECT-19H00926, KAKENHI-PROJECT-21H02064, KAKENHI-PLANNED-19H05761, KAKENHI-PLANNED-19H05784, KAKENHI-PUBLICLY-22H04760, KAKENHI-PUBLICLY-22H04816, KAKENHI-PROJECT-23K23465
  • [Journal Article] Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases.2022

    • Author(s)
      Nishida Y, Yanagisawa S, Morita R, Shigematsu H, Shinzawa-Itoh K, Yuki H, Ogasawara S, et al
    • Journal Title

      Nat Commun.

      Volume: 13 Issue: 1 Pages: 7591-7591

    • DOI

      10.1038/s41467-022-34771-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06130, KAKENHI-PROJECT-22K09391, KAKENHI-PROJECT-21H02064, KAKENHI-PROJECT-20K03794, KAKENHI-PROJECT-20K07338, KAKENHI-PROJECT-21K15443, KAKENHI-PROJECT-21K15776, KAKENHI-PLANNED-18H05425, KAKENHI-PLANNED-19H05761, KAKENHI-PLANNED-19H05784, KAKENHI-PUBLICLY-22H04760, KAKENHI-PUBLICLY-22H04800, KAKENHI-PROJECT-21H02914
  • [Journal Article] Author Correction: Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases2022

    • Author(s)
      Nishida Yuya、 et al., Shiro Yoshitsugu、Honma Teruki、Shigeta Yasuteru、Kubo Minoru、Takashima Seiji、Shintani Yasunori
    • Journal Title

      Nature Communications

      Volume: 13 Issue: 1

    • DOI

      10.1038/s41467-022-35600-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H00926
  • [Journal Article] Structural basis for heme detoxification by an ATP-binding cassette?type efflux pump in gram-positive pathogenic bacteria2022

    • Author(s)
      Nakamura Hiro、Hisano Tamao、Rahman Md. Mahfuzur、Tosha Takehiko、Shirouzu Mikako、Shiro Yoshitsugu
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 119 Issue: 27

    • DOI

      10.1073/pnas.2123385119

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H00926, KAKENHI-PROJECT-21H02064, KAKENHI-PLANNED-19H05761, KAKENHI-PUBLICLY-22H04760
  • [Journal Article] Capacity of extracellular globins to reduce liver fibrosis via scavenging reactive oxygen species and promoting MMP-1 secretion.2022

    • Author(s)
      Hieu VN, Thuy LTT, Hai H, Dat NQ, Hoang DV, Hanh NV, Phuong DM, Hoang TH, Sawai H, Shiro Y, Sato-Matsubara M, Oikawa D, Tokunaga F, Yoshizato K, Kawada N.
    • Journal Title

      Redox Biol.

      Volume: 52 Pages: 102286-102286

    • DOI

      10.1016/j.redox.2022.102286

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H05296, KAKENHI-PROJECT-18H02619, KAKENHI-PUBLICLY-20H05337, KAKENHI-PUBLICLY-21H00291, KAKENHI-PROJECT-19H03641, KAKENHI-PROJECT-21K05281, KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-21K07968, KAKENHI-PROJECT-22K08083, KAKENHI-PROJECT-22K18385, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-19H00926, KAKENHI-PROJECT-21H02688, KAKENHI-PLANNED-19H05761, KAKENHI-PROJECT-23K24322
  • [Journal Article] Short-lived intermediate in N2O generation by P450 NO reductase captured by time-resolved IR spectroscopy and XFEL crystallography2021

    • Author(s)
      Nomura, T., Kimura, T., Kanematsu, Y., Yamada, D., Yamashita, K., Hirata, K., Ueno, G., Murakami, H., Hisano, T., Yamagiwa, R., Takeda, H., Gopalasingam, C., Kousaka, R., Yanagisawa, S., Shoji, O., Kumasaka, T., Yamamoto, M., Takano, Y., Sugimoto, H., Tosha, T., Kubo, M., Shiro, Y
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 118 Issue: 21

    • DOI

      10.1073/pnas.2101481118

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K05698, KAKENHI-PLANNED-19H05761, KAKENHI-PLANNED-19H05784, KAKENHI-PUBLICLY-20H05451, KAKENHI-PLANNED-20H05883, KAKENHI-PROJECT-19H00926, KAKENHI-PROJECT-19H03171, KAKENHI-PROJECT-21H02064
  • [Journal Article] Heme controls the structural rearrangement of its sensor protein mediating the hemolytic bacterial survival2021

    • Author(s)
      Nishinaga Megumi、Sugimoto Hiroshi、Nishitani Yudai、Nagai Seina、Nagatoishi Satoru、Muraki Norifumi、Tosha Takehiko、Tsumoto Kouhei、Aono Shigetoshi、Shiro Yoshitsugu、Sawai Hitomi
    • Journal Title

      Communications Biology

      Volume: 4 Issue: 1 Pages: 467-467

    • DOI

      10.1038/s42003-021-01987-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-19H05761, KAKENHI-PLANNED-19H05762, KAKENHI-PROJECT-19H00926, KAKENHI-PROJECT-17H03093, KAKENHI-PROJECT-18K05321, KAKENHI-PUBLICLY-20H05451, KAKENHI-PROJECT-21H02064, KAKENHI-PROJECT-21H02421, KAKENHI-PROJECT-20K06517, KAKENHI-PROJECT-21K05281, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766
  • [Journal Article] Regulatory Switching by Concerted Motions on the Microsecond Time Scale of the Oxygen Sensor Protein FixL2021

    • Author(s)
      Yamawaki Takeo、Mizuno Misao、Ishikawa Haruto、Takemura Kazuhiro、Kitao Akio、Shiro Yoshitsugu、Mizutani Yasuhisa
    • Journal Title

      The Journal of Physical Chemistry B

      Volume: 125 Issue: 25 Pages: 6847-6856

    • DOI

      10.1021/acs.jpcb.1c01885

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19H05761, KAKENHI-PUBLICLY-20H05439, KAKENHI-PUBLICLY-21H05510, KAKENHI-PROJECT-19H00926, KAKENHI-PROJECT-19H03191, KAKENHI-PROJECT-20H02693
  • [Journal Article] NO Dynamics in Microbial Denitrification System2021

    • Author(s)
      Tosha Takehiko、Yamagiwa Raika、Sawai Hitomi、Shiro Yoshitsugu
    • Journal Title

      Chemistry Letters

      Volume: 50 Issue: 2 Pages: 280-288

    • DOI

      10.1246/cl.200629

    • NAID

      130007986360

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-19H05761, KAKENHI-PUBLICLY-20H05451, KAKENHI-PROJECT-19H00926, KAKENHI-PROJECT-17H03092, KAKENHI-PROJECT-18K05321, KAKENHI-PROJECT-19K22208
  • [Journal Article] Spatially restricted substrate-binding site of cortisol-synthesizing CYP11B1 limits multiple hydroxylations and hinders aldosterone synthesis2021

    • Author(s)
      Mukai Kuniaki、Sugimoto Hiroshi、Kamiya Katsumasa、Suzuki Reiko、Matsuura Tomomi、Hishiki Takako、Shimada Hideo、Shiro Yoshitsugu、Suematsu Makoto、Kagawa Norio
    • Journal Title

      Current Research in Structural Biology

      Volume: 3 Pages: 192-205

    • DOI

      10.1016/j.crstbi.2021.08.001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-19H05761, KAKENHI-PROJECT-19H00926, KAKENHI-PROJECT-20K03794, KAKENHI-PROJECT-21K05294
  • [Journal Article] Impact of membrane protein-lipid interactions on formation of bilayer lipid membranes on SAM-modified gold electrode2021

    • Author(s)
      Kato Masaru、Masuda Yuya、Yoshida Narumi、Tosha Takehiko、Shiro Yoshitsugu、Yagi Ichizo
    • Journal Title

      Electrochimica Acta

      Volume: 373 Pages: 137888-137888

    • DOI

      10.1016/j.electacta.2021.137888

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-19H05761, KAKENHI-PUBLICLY-20H05451, KAKENHI-PROJECT-19H00926, KAKENHI-PROJECT-17H03092, KAKENHI-PROJECT-19H02664
  • [Journal Article] XFEL Crystal Structures of Peroxidase Compound II2021

    • Author(s)
      Kwon, H., Basran, J., Pathak, C., Hussain, M., Freeman, S. L., Fielding, A. J., Bailey, A. J., Stefanou, N., Sparkes, H. A., Tosha, T., Yamashita, K., Hirata, K., Murakami, H., Ueno, G., Ago, H., Tono, K., Yamamoto, M., Sawai, H., Shiro, Y., Sugimoto, H., Raven, E., Moody, P. C. E.
    • Journal Title

      Angewandte Chemie International Edition

      Volume: - Issue: 26 Pages: 14578-14585

    • DOI

      10.1002/anie.202103010

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-20H05452, KAKENHI-PLANNED-19H05761, KAKENHI-PUBLICLY-20H05451, KAKENHI-PROJECT-19H00926, KAKENHI-PROJECT-21H02064, KAKENHI-PROJECT-21K05281
  • [Journal Article] 分子構造を基盤にしたヘムタンパク質・ヘム酵素の機能解明2020

    • Author(s)
      城 宜嗣
    • Journal Title

      BJSCC

      Volume: 75 Pages: 51-56

    • NAID

      130007879402

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H00926
  • [Journal Article] 分子構造を基盤にしたヘムタンパク質・ヘム酵素の機能解明2020

    • Author(s)
      城 宜嗣
    • Journal Title

      BJSCC

      Volume: 75 Pages: 51-56

    • NAID

      130007879402

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Journal Article] Timing of NO Binding and Protonation in the Catalytic Reaction of Bacterial Nitric Oxide Reductase as Established by Time-Resolved Spectroscopy.2020

    • Author(s)
      Hanae Takeda, Tatsunari Kimura, Takashi Nomura, Masaki Horitani, Azusa Yokota, Akiko Matsubayashi, Shoko Ishii, Yoshitsugu Shiro, Minoru Kubo and Takehiko Tosha
    • Journal Title

      Bulletin of the Chemical Society of Japan

      Volume: - Issue: 7 Pages: 825-833

    • DOI

      10.1246/bcsj.20200038

    • NAID

      130007879554

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19J15471, KAKENHI-PLANNED-19H05761, KAKENHI-PLANNED-19H05784, KAKENHI-PUBLICLY-20H05451, KAKENHI-PROJECT-19H00926, KAKENHI-PROJECT-17H03092, KAKENHI-PROJECT-19H03171, KAKENHI-PROJECT-19K22208, KAKENHI-PROJECT-18H02412
  • [Journal Article] The active form of quinol-dependent nitric oxide reductase from Neisseria meningitidis is a dimer2020

    • Author(s)
      Jamali M. Arif M.、Gopalasingam Chai C.、Johnson Rachel M.、Tosha Takehiko、Muramoto Kazumasa、Muench Stephen P.、Antonyuk Svetlana V.、Shiro Yoshitsugu、Hasnain Samar S.
    • Journal Title

      IUCrJ

      Volume: 7 Issue: 3 Pages: 404-415

    • DOI

      10.1107/s2052252520003656

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06162, KAKENHI-PLANNED-19H05761, KAKENHI-PROJECT-19H00926
  • [Journal Article] Missing Piece of Two-Component Signal Transduction Systems Unveiled by SEC-SAXS2019

    • Author(s)
      H. Sawai, Y. Shiro
    • Journal Title

      SPring-8/SACLA Research Frontiers 2018

      Volume: - Pages: 15-16

    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Journal Article] Chemomechanical Coupling in the Transport Cycle of a Type II ABC Transporter2019

    • Author(s)
      K. Tamura, H. Sugimoto, Y. Shiro, Y. Sugita
    • Journal Title

      J. Phys. Chem. B

      Volume: 123 Issue: 34 Pages: 7270-7281

    • DOI

      10.1021/acs.jpcb.9b04356

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19H05761, KAKENHI-PROJECT-19H00926, KAKENHI-PROJECT-18H02396
  • [Journal Article] Dimeric structures of quinol-dependent nitric oxide reductases (qNORs) revealed by cryo-electron microscopy2019

    • Author(s)
      Gopalasingam Chai C.、Johnson Rachel M.、Chiduza George N.、Tosha Takehiko、Yamamoto Masaki、Shiro Yoshitsugu、Antonyuk Svetlana V.、Muench Stephen P.、Hasnain S. Samar
    • Journal Title

      Science Advances

      Volume: 5 Issue: 8

    • DOI

      10.1126/sciadv.aax1803

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22208, KAKENHI-PLANNED-19H05761, KAKENHI-PROJECT-19H00926, KAKENHI-PROJECT-17H03092
  • [Journal Article] UV Resonance Raman Characterization of a Substrate Bound to Human Indoleamine 2,3-Dioxygenase 12019

    • Author(s)
      Sachiko Yanagisawa , Kure’e Kayama , Masayuki Hara , Hiroshi Sugimoto , Yoshitsugu Shiro , Takashi Ogura
    • Journal Title

      Biophysical Journal

      Volume: 117 Issue: 4 Pages: 706-716

    • DOI

      10.1016/j.bpj.2019.07.017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K05698, KAKENHI-PLANNED-19H05761, KAKENHI-PROJECT-19H00926
  • [Journal Article] Roles of N- and C-terminal domains in the ligand-binding properties of cytoglobin2018

    • Author(s)
      S. Hanai, H.i Tsujino, T. Yamashita, R. Torii, H. Sawai, Y. Shiro, K. Oohora, T. Hayashi, T. Uno
    • Journal Title

      J. Inorg. Biochem.

      Volume: 179 Pages: 1-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Journal Article] Pseudomonas aeruginosa overexpression system of nitric oxide reductase for in vivo and in vitro mutational analyses2018

    • Author(s)
      Yamagiwa Raika、Kurahashi Takuya、Takeda Mariko、Adachi Mayuho、Nakamura Hiro、Arai Hiroyuki、Shiro Yoshitsugu、Sawai Hitomi、Tosha Takehiko
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - Bioenergetics

      Volume: 1859 Issue: 5 Pages: 333-341

    • DOI

      10.1016/j.bbabio.2018.02.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H03092, KAKENHI-PROJECT-15K07351, KAKENHI-PROJECT-18K05321, KAKENHI-PROJECT-26220807
  • [Journal Article] Identification of an Internal Cavity in the PhoQ Sensor Domain for PhoQ Activity and SafA-mediated Control2018

    • Author(s)
      K. Yoshitani, E. Ishii, K. Taniguchi, H. Sugimoto, Y. Shiro, H. Mori, Y. Akiyama, A. Kato, R. Utsumi, Y. Eguchi
    • Journal Title

      Bioscience, Biotechnology, and Biochemistry

      Volume: 83 Issue: 4 Pages: 684-694

    • DOI

      10.1080/09168451.2018.1562879

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26220807, KAKENHI-PROJECT-18H02404, KAKENHI-PROJECT-17J02501, KAKENHI-PROJECT-16K07681
  • [Journal Article] Reconstitution of Full-Length P450BM3 with an Artificial Metal Complex by Utilising the Transpeptidase Sortase A2018

    • Author(s)
      K. Omura, Y. Aiba, H. Onoda, J. K. Stanfield, S. Ariyasu, H. Sugimoto, Y. Shiro, O. Shoji, Y. Watanabe
    • Journal Title

      Chem. Commun.

      Volume: 54 Issue: 57 Pages: 7892-7895

    • DOI

      10.1039/c8cc02760a

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-15H05806, KAKENHI-PROJECT-26220807
  • [Journal Article] Mechanistic Insights into the Activation of Soluble Guanylate Cyclase by Carbon Monoxide: A Multi-Step Mechanism Proposed for the BAY 41-2272-Induced Formation of 5-Coordinate CO Heme2018

    • Author(s)
      Ryu Makino, Yuji Obata, Motonari Tsubaki, Tetsutaro Iizuka, Yuki Hamajima,Yasuyuki Kato-Yamada, Keisuke Mashima, and Yoshitsugu Shiro
    • Journal Title

      Biochemistry

      Volume: 57 Issue: 10 Pages: 1620-1631

    • DOI

      10.1021/acs.biochem.7b01240

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K07323, KAKENHI-PROJECT-26220807
  • [Journal Article] Surface-Enhanced Infrared Absorption Spectroscopy of Bacterial Nitric Oxide Reductase under Electrochemical Control Using Vibrational Probe of Carbon Monoxide2018

    • Author(s)
      M. Kato, S. Nakagawa, T. Tosha, Y. Shiro, Y. Masuda, K. Nakata, I. Yagi
    • Journal Title

      J. Phys. Chem. Lett.

      Volume: 9 Issue: 17 Pages: 5196-5200

    • DOI

      10.1021/acs.jpclett.8b02581

    • NAID

      120006887743

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26220807, KAKENHI-PROJECT-17H03092, KAKENHI-PROJECT-16K20882
  • [Journal Article] Structural basis for promotion of duodenal iron absorption by enteric ferric reductase with ascorbate.2018

    • Author(s)
      Ganasen M, Togashi H, Takeda H, Asakura H, Tosha T, Yamashita K, Hirata K, Nariai Y, Urano T, Yuan X, Hamza I, Mauk AG, Shiro Y, Sugimoto H, Sawai H.
    • Journal Title

      Communications Biology

      Volume: 1 Issue: 1 Pages: 120-120

    • DOI

      10.1038/s42003-018-0121-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08983, KAKENHI-PROJECT-18K05321, KAKENHI-PROJECT-26220807, KAKENHI-PROJECT-17H03092, KAKENHI-PROJECT-18H02396
  • [Journal Article] Identification of a novel zinc-binding protein, C1orf123, as an interactor with a heavy metal-associated domain2018

    • Author(s)
      Furukawa Yoshiaki、Lim Carolyn、Tosha Takehiko、Yoshida Koki、Hagai Tomoaki、Akiyama Shuji、Watanabe Shoji、Nakagome Kenta、Shiro Yoshitsugu
    • Journal Title

      PLOS ONE

      Volume: 13 Issue: 9 Pages: e0204355-e0204355

    • DOI

      10.1371/journal.pone.0204355

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-17H05705, KAKENHI-PUBLICLY-18H04564, KAKENHI-PROJECT-17H06165, KAKENHI-PROJECT-26220807, KAKENHI-PROJECT-16H04768, KAKENHI-PROJECT-17H03092
  • [Journal Article] Characterization of the Quinol-dependent Nitric Oxide Reductase from the Pathogen Neisseria meningitidis, an Electrogenic Enzyme2018

    • Author(s)
      N. Gonska, D. R. Young, R. Yuki, T. Okamoto, T. Hisano, S. V. Antonyuk, S. S. Hasnain, K. Muramoto, Y. Shiro, T. Tosha, P. Adelroth
    • Journal Title

      Sci. Rep.

      Volume: 8: 3637 Issue: 1 Pages: 3637-3637

    • DOI

      10.1038/s41598-018-21804-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220807, KAKENHI-PROJECT-17H03092, KAKENHI-PROJECT-15K07029
  • [Journal Article] Architecture of a Complete Two-Component Signal Transduction System: Oxygen-Sensing Proteins FixL, FixJ, and Their Complex2018

    • Author(s)
      G. S. A. Wright, A. Saeki, T. Hikima, Y. Nishizono, T. Hisano, M. Yamamoto, S. V. Antonyuk, S. S. Hasnain, Y. Shiro, H. Sawai
    • Journal Title

      Sci. Signal.

      Volume: 11 Issue: 525

    • DOI

      10.1126/scisignal.aaq0825

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220807, KAKENHI-PROJECT-18K05321
  • [Journal Article] Dynamics of Nitric Oxide Controlled by Protein Complex in Bacterial System2017

    • Author(s)
      E. Terasakaa, K. Yamada, P.-H. Wang, K. Hosokawa, R. Yamagiwa, K. Matsumoto, S. Ishii, T. Mori, K. Yagi, H. Sawai, H. Arai, H. Sugimotoa, Y. Sugitac, Y. Shiroa, T. Tosha
    • Journal Title

      Proc. Natl. Acd. SCI. USA

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26620140
  • [Journal Article] Direct Hydroxylation of Benzene to Phenol by Cytochrome P450BM3 Triggered by Amino Acid Derivatives2017

    • Author(s)
      Shoji Osami、Yanagisawa Sota、Stanfield Joshua Kyle、Suzuki Kazuto、Cong Zhiqi、Sugimoto Hiroshi、Shiro Yoshitsugu、Watanabe Yoshihito
    • Journal Title

      Angewandte Chemie International Edition

      Volume: 56 Issue: 35 Pages: 10324-10329

    • DOI

      10.1002/anie.201703461

    • NAID

      120006382269

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-15H05806, KAKENHI-PROJECT-26220807
  • [Journal Article] Dynamics of Nitric Oxide Controlled by Protein Complex in Bacterial System2017

    • Author(s)
      E. Terasakaa, K. Yamada, P.-H. Wang, K. Hosokawa, R. Yamagiwa, K. Matsumoto, S. Ishii, T. Mori, K. Yagi, H. Sawai, H. Arai, H. Sugimotoa, Y. Sugitac, Y. Shiroa, T. Tosha
    • Journal Title

      Proc. Natl. Acd. SCI. USA

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Journal Article] Structures of the Heme Acquisition Protein HasA with Iron(III)-5,15-Diphenylporphyrin and Derivatives Thereof as an Artificial Prosthetic Group2017

    • Author(s)
      Uehara Hiromu、Shisaka Yuma、Nishimura Tsubasa、Sugimoto Hiroshi、Shiro Yoshitsugu、Miyake Yoshihiro、Shinokubo Hiroshi、Watanabe Yoshihito、Shoji Osami
    • Journal Title

      Angewandte Chemie International Edition

      Volume: 56 Issue: 48 Pages: 15279-15283

    • DOI

      10.1002/anie.201707212

    • NAID

      120006382255

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26708018, KAKENHI-PLANNED-15H05806, KAKENHI-PUBLICLY-16H01013, KAKENHI-PROJECT-26220807, KAKENHI-PROJECT-17H01190
  • [Journal Article] Structural basis for binding and transfer of heme in bacterial heme-acquisition systems2017

    • Author(s)
      Naoe Youichi、Nakamura Nozomi、Rahman Md. Mahfuzur、Tosha Takehiko、Nagatoishi Satoru、Tsumoto Kouhei、Shiro Yoshitsugu、Sugimoto Hiroshi
    • Journal Title

      Proteins: Structure, Function, and Bioinformatics

      Volume: 85 Issue: 12 Pages: 2217-2230

    • DOI

      10.1002/prot.25386

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-17H05896, KAKENHI-PROJECT-26220807, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-17H03092
  • [Journal Article] Control of stereoselectivity of benzylic hydroxylation catalysed by wild-type cytochrome P450BM3 using decoy molecules2017

    • Author(s)
      Suzuki Kazuto、Stanfield Joshua Kyle、Shoji Osami、Yanagisawa Sota、Sugimoto Hiroshi、Shiro Yoshitsugu、Watanabe Yoshihito
    • Journal Title

      Catalysis Science & Technology

      Volume: 7 Issue: 15 Pages: 3332-3338

    • DOI

      10.1039/c7cy01130j

    • NAID

      120006382270

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-15H05806, KAKENHI-PROJECT-26220807
  • [Journal Article] Dynamics of Nitric Oxide Controlled by Protein Complex in Bacterial System2017

    • Author(s)
      Erina Terasaka, Kenta Yamada, Po-Hung Wang, Kanta Hosokawa, Raika Yamagiwa, Kimi Matsumoto, Shoko Ishii, Takaharu Mori, Kiyoshi Yagi, Hitomi Sawai, Hiroyuki Arai, Hiroshi Sugimoto, Yuji Sugita, Yoshitsugu Shiro and Takehiko Tosha
    • Journal Title

      PNAS

      Volume: 114 Issue: 37 Pages: 9888-9893

    • DOI

      10.1073/pnas.1621301114

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26119006, KAKENHI-PROJECT-26220807, KAKENHI-PROJECT-17H03092, KAKENHI-PROJECT-15K07351
  • [Journal Article] Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate2017

    • Author(s)
      Tosha Takehiko、Kubo Minoru, et. al
    • Journal Title

      Nature Communications

      Volume: 8 Issue: 1 Pages: 1-9

    • DOI

      10.1038/s41467-017-01702-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05806, KAKENHI-PUBLICLY-17H05896, KAKENHI-PLANNED-26105012, KAKENHI-PROJECT-26220807, KAKENHI-PROJECT-15H03841, KAKENHI-PROJECT-17H03092, KAKENHI-PROJECT-15H05476, KAKENHI-PROJECT-15K18487
  • [Journal Article] Crystal structure of bacterial haem importer complex in the inward-facing conformation2016

    • Author(s)
      Naoe, Y., Nakamura, N., Doi, A., Sawabe, M., Nakamura, H., Shiro, Y., Sugimoto, H.
    • Journal Title

      Nature Communications

      Volume: 7 Issue: 1 Pages: 13411-13411

    • DOI

      10.1038/ncomms13411

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H01655, KAKENHI-PROJECT-26220807, KAKENHI-PROJECT-26620140
  • [Journal Article] A Nearly On-axis Spectroscopic System for Simultaneously Measuring UV-visible Absorption and X-ray Diffraction in the SPring-8 Structural Genomics Beamline2016

    • Author(s)
      M. Sakaguchi, T. Kimura, T. Nishida, T. Tosha, Y. Yamaguchi, S. Yanagisawa, G. Ueno, H. Murakami, H. Ago, M. Yamamoto, T. Ogura, Y. Shiro, M. Kubo
    • Journal Title

      J. Synchro. Rad.

      Volume: 23 Issue: 1 Pages: 334-338

    • DOI

      10.1107/s1600577515018275

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26620140, KAKENHI-PUBLICLY-15H00960, KAKENHI-PUBLICLY-15H00965, KAKENHI-PUBLICLY-15H01055, KAKENHI-PUBLICLY-15H01655, KAKENHI-PUBLICLY-26104532, KAKENHI-PROJECT-26220807, KAKENHI-PROJECT-15H05476, KAKENHI-PUBLICLY-16H00848
  • [Journal Article] A Substrate-Binding-State Mimic of H2O2-Dependent Cytochrome P450 Produced by One-point Mutagenesis and Peroxygenation of Non-native Substrates2016

    • Author(s)
      O. Shoji, T. Fujishiro, K. Nishio, Y. Kano, H. Kimoto, S. Chien, H. Onoda, A. Muramatsu, S. Tanaka, A. Hori, H. Sugimoto, Y. Shiro, Y. Watanabe
    • Journal Title

      Catal. Sci. Tech.

      Volume: 6 Issue: 15 Pages: 5806-5811

    • DOI

      10.1039/c6cy00630b

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05806, KAKENHI-PROJECT-24225004, KAKENHI-PROJECT-26220807, KAKENHI-PROJECT-16J02846, KAKENHI-PROJECT-14J09744, KAKENHI-PROJECT-26620140
  • [Journal Article] Regulatory Implications of Structural Changes in Tyr201 of the Oxygen Sensor Protein FixL2016

    • Author(s)
      Takeo Yamawaki, Haruto Ishikawa, Misao Mizuno, Hiro Nakamura, Yoshitsugu Shiro, and Yasuhisa Mizutani
    • Journal Title

      Biochemistry

      Volume: 55 Issue: 29 Pages: 4027-4035

    • DOI

      10.1021/acs.biochem.6b00405

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-15H01639, KAKENHI-PROJECT-26220807, KAKENHI-PROJECT-26620140, KAKENHI-PROJECT-16K13933, KAKENHI-PROJECT-16K14712, KAKENHI-PLANNED-25104006
  • [Journal Article] A Study of the Dynamics of the Heme Pocket and C-helix in CooA Upon CO Dissociation Using Time-resolved Visible and UV Resonance Raman Spectroscopy2016

    • Author(s)
      Akihiro Otomo, Haruto Ishikawa, Misao Mizuno, Tetsunari Kimura, Minoru Kubo, Yoshitsugu Shiro, Shigetoshi Aono, and Yasuhisa Mizutani
    • Journal Title

      J. Phys. Chem. B

      Volume: 120 Issue: 32 Pages: 7836-7843

    • DOI

      10.1021/acs.jpcb.6b05634

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-15H01639, KAKENHI-PROJECT-26220807, KAKENHI-PROJECT-15H03841, KAKENHI-PROJECT-15H05476, KAKENHI-PROJECT-15K12221, KAKENHI-PROJECT-26620140, KAKENHI-PROJECT-16K13933, KAKENHI-PROJECT-16K14712, KAKENHI-PLANNED-25104006
  • [Journal Article] Contribution of the Distal Pocket Residue to the Acyl-chain-length Substrate Specificity of (R)-specific Enoyl-CoA Hydratases from Pseudomonas: Site-directed Mutagenesis, Chimeragenesis, X-ray Crystallographic Analysis, and Homology Modeling2015

    • Author(s)
      T. Tsuge, S. Sato, A. Hiroe, K. Ishizuka, H. Kanazawa, Y. Shiro, T. Hisano
    • Journal Title

      Appl. Environm. Microbio.

      Volume: 81 Issue: 23 Pages: 8076-8083

    • DOI

      10.1128/aem.02412-15

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26620140, KAKENHI-PROJECT-26220807
  • [Journal Article] The Initial O2 Inserting Step of Tryptophan Dioxygenase Reaction Proposed by a Heme-Modification Study2015

    • Author(s)
      R. Makino, E. Obayashi, H. Hori, T. Iizuka, K. Mashima, Y. Shiro, Y. Ishimura
    • Journal Title

      Biochemistry

      Volume: 54 Issue: 23 Pages: 3604-3616

    • DOI

      10.1021/acs.biochem.5b00048

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26620140, KAKENHI-PROJECT-26220807
  • [Journal Article] Crystal Structure of Response Regulator ChrA in the Heme-Sensing Two-Component System of Corynebacterium diphtheriae2015

    • Author(s)
      A. Doi, H. Nakamura, Y. Shiro, H. Sugimoto
    • Journal Title

      Acta Crysll. F

      Volume: 71 Issue: 8 Pages: 966-971

    • DOI

      10.1107/s2053230x15009838

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26620140, KAKENHI-PUBLICLY-15H01655, KAKENHI-PROJECT-26220807, KAKENHI-PROJECT-24687015
  • [Journal Article] Structure-function Analyses of Cytochrome P450revI Involved in Reveromycin A Biosynthesis and Evaluation of the Biological Activity of Its Aubstrate, Reveromycin T2014

    • Author(s)
      S. Takahashi, S. Nagano, T. Nogawa, N. Kanoh, M. Uramoto, M. Kawatani, T. Shimizu, T. Miyazawa, Y. Shiro, H. Osada
    • Journal Title

      J. Biol. Chem.

      Volume: 289 Pages: 32446-32458

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26620140
  • [Journal Article] Palladium-Nanoparticle-Catalyzed 1,7-Palladium Migration Involving C-H Activation, Followed by Intramolecular Amination: Regioselective Synthesis of N1-Arylbenzotriazoles and an Evaluation of Their Inhibitory Activity Towards Indoleamine 2,3-Dioxygenase2014

    • Author(s)
      K. Takagi, M. Al-Amin, N. Hoshiya, J. Wouters, H. Sugimoto, Y. Shiro, H. Fukuda, S. Shuto, M. Arisawa
    • Journal Title

      J. Org. Chem.

      Volume: 79 Pages: 6366-6371

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Structure-function Analyses of Cytochrome P450revI Involved in Reveromycin A Biosynthesis and Evaluation of the Biological Activity of Its Aubstrate, Reveromycin T2014

    • Author(s)
      S. Takahashi, S. Nagano, T. Nogawa, N. Kanoh, M. Uramoto, M. Kawatani, T. Shimizu, T. Miyazawa, Y. Shiro, H. Osada
    • Journal Title

      J. Biol. Chem.

      Volume: 289 Pages: 32446-32458

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Journal Article] An in vivo Inhibitory Effect on the Heme Uptake of Pseudomonas aeruginosa by Its Hemophore (HasAp) Carrying Synthetic Metal Complexes.2014

    • Author(s)
      Shirataki, C.; Shoji, O.; Terada, M.; Ozaki, S.; Sugimoto, H.; Shiro, Y.; Watanabe, Y.
    • Journal Title

      Angw. Chem. Int. Ed.

      Volume: 53 Issue: 11 Pages: 2862-2866

    • DOI

      10.1002/anie.201307889

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22105012, KAKENHI-PROJECT-24225004, KAKENHI-PUBLICLY-25105724, KAKENHI-PUBLICLY-25121739, KAKENHI-PROJECT-26708018
  • [Journal Article] Activation of Wild-type Cytochrome P450BM3 by the Next Generation of Decoy Molecules: Enhanced Hydroxylation of Gaseous Alkanes and Crystallographic Evidence2014

    • Author(s)
      Z. Cong, O. Shoji, C. Kasai, N. Kawakami, H. Sugimoto, Y. Shiro, Y. Watanabe
    • Journal Title

      ACS Catalysis

      Volume: 5 Pages: 150-156

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Characterization of Quinol-Dependent Nitric Oxide Reductase from Geobacillus Stearothermophilus: Enzymatic Activity and Active Site Structure2014

    • Author(s)
      E. Terasaka, N. Okada, N. Sato, Y. Sako, Y. Shiro, T. Tosha
    • Journal Title

      Biochim. Biophys. Acta - Bioenergetics

      Volume: 1837 Pages: 1019-1026

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Disulfide Bonds Regulate Binding of Exogenous Ligand to Human Cytoglobin2014

    • Author(s)
      H. Tsujino, T. Yamashita, A. Nose, K. Kukino, H. Sawai, Y. Shiro, T. Uno
    • Journal Title

      J. Inor. Biochem.

      Volume: 135 Pages: 20-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Journal Article] Structures of Reduced and Ligand-Bound Nitric Oxide Reductase Provide Insights into Functional Differences in Respiratory Enzymes2014

    • Author(s)
      N. Sato, S. Ishii, H. Sugimoto, T. Hino, Y. Fukumori, Y. Sako, Y. Shiro, T. Tosha
    • Journal Title

      PROTEINS: Structure, Function, and Bioinformatics

      Volume: 82 Pages: 1258-1271

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Journal Article] Crystal Structure, Exogenous Ligand Binding and Redox Properties of an Engineered Diiron Active Site in a Bacterial Hemerythrin2014

    • Author(s)
      A. Onoda, Y. Okamoto, H. Sugimoto, Y. Takano, S. Hirota, D. Kurtz, Y. Shiro, T. Hayashi
    • Journal Title

      Chem. Comm.

      Volume: 50 Pages: 3421-3423

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Journal Article] An in vivo Inhibitory Effect on the Heme Uptake of Pseudomonas aeruginosa by Its Hemophore (HasAp) Carrying Synthetic Metal Complexes2014

    • Author(s)
      C. Shirataki, O. Shoji, M. Terada, S. Ozaki, H. Sugimoto, Y. Shiro, Y. Watanabe
    • Journal Title

      Angw. Chem. Int. Ed.

      Volume: 53 Pages: 2862-2866

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Journal Article] Palladium-Nanoparticle-Catalyzed 1,7-Palladium Migration Involving C-H Activation, Followed by Intramolecular Amination: Regioselective Synthesis of N1-Arylbenzotriazoles and an Evaluation of Their Inhibitory Activity Towards Indoleamine 2,3-Dioxygenase2014

    • Author(s)
      K. Takagi, M. Al-Amin, N. Hoshiya, J. Wouters, H. Sugimoto, Y. Shiro, H. Fukuda, S. Shuto, M. Arisawa
    • Journal Title

      J. Org. Chem.

      Volume: 79 Pages: 6366-6371

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26620140
  • [Journal Article] An in vivo Inhibitory Effect on the Heme Uptake of Pseudomonas aeruginosa by Its Hemophore (HasAp) Carrying Synthetic Metal Complexes2014

    • Author(s)
      C. Shirataki, O. Shoji, M. Terada, S. Ozaki, H. Sugimoto, Y. Shiro, Y. Watanabe
    • Journal Title

      Angw. Chem. Int. Ed.

      Volume: 53 Pages: 2862-2866

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26620140
  • [Journal Article] Palladium-Nanoparticle-Catalyzed 1,7-Palladium Migration Involving C-H Activation, Followed by Intramolecular Amination: Regioselective Synthesis of N1-Arylbenzotriazoles and an Evaluation of Their Inhibitory Activity Towards Indoleamine 2,3-Dioxygenase2014

    • Author(s)
      K. Takagi, M. Al-Amin, N. Hoshiya, J. Wouters, H. Sugimoto, Y. Shiro, H. Fukuda, S. Shuto, M. Arisawa
    • Journal Title

      J. Org. Chem.

      Volume: 79 Pages: 6366-6371

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Journal Article] Activation of Wild-type Cytochrome P450BM3 by the Next Generation of Decoy Molecules: Enhanced Hydroxylation of Gaseous Alkanes and Crystallographic Evidence2014

    • Author(s)
      Z. Cong, O. Shoji, C. Kasai, N. Kawakami, H. Sugimoto, Y. Shiro, Y. Watanabe
    • Journal Title

      ACS Catalysis

      Volume: 5 Pages: 150-156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26620140
  • [Journal Article] Characterization of Quinol-Dependent Nitric Oxide Reductase from Geobacillus Stearothermophilus: Enzymatic Activity and Active Site Structure2014

    • Author(s)
      E. Terasaka, N. Okada, N. Sato, Y. Sako, Y. Shiro, T. Tosha
    • Journal Title

      Biochim. Biophys. Acta - Bioenergetics

      Volume: 1837 Pages: 1019-1026

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Journal Article] Activation of Wild-type Cytochrome P450BM3 by the Next Generation of Decoy Molecules: Enhanced Hydroxylation of Gaseous Alkanes and Crystallographic Evidence2014

    • Author(s)
      Z. Cong, O. Shoji, C. Kasai, N. Kawakami, H. Sugimoto, Y. Shiro, Y. Watanabe
    • Journal Title

      ACS Catalysis

      Volume: 5 Pages: 150-156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Journal Article] Structure-function Analyses of Cytochrome P450revI Involved in Reveromycin A Biosynthesis and Evaluation of the Biological Activity of Its Aubstrate, Reveromycin T2014

    • Author(s)
      S. Takahashi, S. Nagano, T. Nogawa, N. Kanoh, M. Uramoto, M. Kawatani, T. Shimizu, T. Miyazawa, Y. Shiro, H. Osada
    • Journal Title

      J. Biol. Chem.

      Volume: 289 Pages: 32446-32458

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Crystal Structure, Exogenous Ligand Binding and Redox Properties of an Engineered Diiron Active Site in a Bacterial Hemerythrin2014

    • Author(s)
      A. Onoda, Y. Okamoto, H. Sugimoto, Y. Takano, S. Hirota, D. Kurtz, Y. Shiro, T. Hayashi
    • Journal Title

      Chem. Comm.

      Volume: 50 Pages: 3421-3423

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Disulfide Bonds Regulate Binding of Exogenous Ligand to Human Cytoglobin2014

    • Author(s)
      H. Tsujino, T. Yamashita, A. Nose, K. Kukino, H. Sawai, Y. Shiro, T. Uno
    • Journal Title

      J. Inor. Biochem.

      Volume: 135 Pages: 20-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26620140
  • [Journal Article] Crystal Structure, Exogenous Ligand Binding and Redox Properties of an Engineered Diiron Active Site in a Bacterial Hemerythrin2014

    • Author(s)
      A. Onoda, Y. Okamoto, H. Sugimoto, Y. Takano, S. Hirota, D. Kurtz, Y. Shiro, T. Hayashi
    • Journal Title

      Chem. Comm.

      Volume: 50 Pages: 3421-3423

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26620140
  • [Journal Article] Structures of Reduced and Ligand-Bound Nitric Oxide Reductase Provide Insights into Functional Differences in Respiratory Enzymes2014

    • Author(s)
      N. Sato, S. Ishii, H. Sugimoto, T. Hino, Y. Fukumori, Y. Sako, Y. Shiro, T. Tosha
    • Journal Title

      PROTEINS: Structure, Function, and Bioinformatics

      Volume: 82 Pages: 1258-1271

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26620140
  • [Journal Article] An in vivo Inhibitory Effect on the Heme Uptake of Pseudomonas aeruginosa by Its Hemophore (HasAp) Carrying Synthetic Metal Complexes2014

    • Author(s)
      C. Shirataki, O. Shoji, M. Terada, S. Ozaki, H. Sugimoto, Y. Shiro, Y. Watanabe
    • Journal Title

      Angw. Chem. Int. Ed.

      Volume: 53 Pages: 2862-2866

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Disulfide Bonds Regulate Binding of Exogenous Ligand to Human Cytoglobin2014

    • Author(s)
      H. Tsujino, T. Yamashita, A. Nose, K. Kukino, H. Sawai, Y. Shiro, T. Uno
    • Journal Title

      J. Inor. Biochem.

      Volume: 135 Pages: 20-27

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Structures of Reduced and Ligand-Bound Nitric Oxide Reductase Provide Insights into Functional Differences in Respiratory Enzymes2014

    • Author(s)
      N. Sato, S. Ishii, H. Sugimoto, T. Hino, Y. Fukumori, Y. Sako, Y. Shiro, T. Tosha
    • Journal Title

      PROTEINS: Structure, Function, and Bioinformatics

      Volume: 82 Pages: 1258-1271

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Characterization of Quinol-Dependent Nitric Oxide Reductase from Geobacillus Stearothermophilus: Enzymatic Activity and Active Site Structure2014

    • Author(s)
      E. Terasaka, N. Okada, N. Sato, Y. Sako, Y. Shiro, T. Tosha
    • Journal Title

      Biochim. Biophys. Acta - Bioenergetics

      Volume: 1837 Pages: 1019-1026

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26620140
  • [Journal Article] Crystal Structures of Nitric Oxide Reductases Provide Key Insights into Functional Conversion of Respiratory Enzymes2013

    • Author(s)
      T. Tosha, Y. Shiro
    • Journal Title

      IUBMB Life

      Volume: 65 Pages: 217-226

    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Resonance Raman Study on Indoleamine 2,3-Dioxygenase: Control of Reactivity by Substrate-binding.2013

    • Author(s)
      Yanagisawa, S.; Hara, M.; Sugimoto, H.; Shiro, Y.; Ogura T.
    • Journal Title

      Chem. Phys.

      Volume: 419 Pages: 178-183

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Ultraviolet Resonance Raman Observation of the Structural Dynamics of FixL on Ligand Recognition.2013

    • Author(s)
      Yano, S.; Ishikawa, H.; Mizuno, M.; Nakamura, H.; Shiro, Y.; Mizutani, Y.
    • Journal Title

      J. Phys. Chem. B,

      Volume: 117 Pages: 15786-15791

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Crystal Structures of Nitric Oxide Reductases Provide Key Insights into Functional Conversion of Respiratory Enzymes2013

    • Author(s)
      T. Tosha, Y. Shiro
    • Journal Title

      IUBMB Life

      Volume: 65 Pages: 217-226

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Crystal Structures of Nitric Oxide Reductases Provide Key Insights into Functional Conversion of Respiratory Enzymes2013

    • Author(s)
      T. Tosha, Y. Shiro
    • Journal Title

      IUBMB (International Union of Biochemistry and Molecular Biology)

      Volume: Life 65 Pages: 217-226

    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Molecular Dynamic Simulations Reveal Proton Transfer Pathways in Cytochrome C-Dependent Nitric Oxide Reductase2012

    • Author(s)
      A. V. Pisliakov, T. Hino, Y. Shiro, Y. Sugita
    • Journal Title

      POLS Comp. Biol

      Volume: 8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Proton Transfer in the Quinol-dependent Nitric Oxide Reductase from Geobacillus stearothermophilus during Reduction of Oxygen2012

    • Author(s)
      L. Salomonsson, J. Reimann, T. Tosha, N. Krause, N. Gonska, Y. Shiro, P. Adelroth
    • Journal Title

      Biochim. Biophys. Acta - Bioenergetics

      Volume: 1817 Pages: 1914-1920

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Structural Basis for Nitrous Oxide Generation by Bacterial Nitric Oxide Reductases2012

    • Author(s)
      Y. Shiro, H. Sugimoto, T. Tosha, S. Nagano, T. Hino
    • Journal Title

      Philosophical Transactions B, The Royal Society

      Volume: 367 Pages: 1195-1203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Structure and Function of Bacterial Nitric Oxide Reductases, Anaerobic Enzymes2012

    • Author(s)
      Y. Shiro
    • Journal Title

      Biochim. Biophys. Acta - Bioenergetics

      Volume: 1817 Pages: 1917-1913

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Chiral Substrate Analogues Assisted Stereoselective Epoxidation Catalyzed by H_2O_2-Dependent Cytochrome P450SPa2012

    • Author(s)
      T. Fujishiro, O. Shoji, N. Kawakami, T. Watanabe, H. Sugimoto, Y. Shiro, Y. Watanabe
    • Journal Title

      Chem. Asian J

      Volume: 7 Pages: 2286-2293

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Proton Transfer in the Quinol-dependent Nitric Oxide Reductase from Geobacillus stearothermophilus during Reduction of Oxygen2012

    • Author(s)
      L. Salomonsson, J. Reimann, T. Tosha, N. Krause, N. Gonska, Y. Shiro, P. Adelroth
    • Journal Title

      Biochim. Biophys. Acta - Bioenergetics

      Volume: 1817 Pages: 1914-1920

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Chiral Substrate Analogues Assisted Stereoselective Epoxidation Catalyzed by H2O2-Dependent Cytochrome P450SPα2012

    • Author(s)
      T. Fujishiro, O. Shoji, N. Kawakami, T. Watanabe, H. Sugimoto, Y. Shiro, Y. Watanabe
    • Journal Title

      Chem. Asian J.

      Volume: 7 Pages: 2286-2293

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Diversity and Substrate Specificity in the Structures of Steroidogenic Cytochrome P450 Enzymes2012

    • Author(s)
      H. Sugimoto, Y. Shiro
    • Journal Title

      Biol. Pharm. Bull.

      Volume: 35 Pages: 818-823

    • NAID

      130001872159

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Coupling Reaction of Indolepyruvic Acid by StaD and Its Product: Implications of Biosynthesis of Indolocarbazole and Violacein2012

    • Author(s)
      S. Asamizu, S. Hirano, H. Onaka, H. Koshino, Y. Shiro, S. Nagano
    • Journal Title

      ChemBioChem

      Volume: 13 Pages: 2495-2500

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Chiral Substrate Analogues Assisted Stereoselective Epoxidation Catalyzed by H2O2-Dependent Cytochrome P450SPα2012

    • Author(s)
      T. Fujishiro, O. Shoji, N. Kawakami, T. Watanabe, H. Sugimoto, Y. Shiro, Y. Watanabe
    • Journal Title

      Chem. Asian J.

      Volume: 7 Pages: 2286-2293

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] 一酸化窒素還元酵素の結晶構造から見えてきた呼吸酵素の機能変換2012

    • Author(s)
      日野智也、當舍武彦、城 宜嗣
    • Journal Title

      生物物理

      Volume: 52 Pages: 186-189

    • NAID

      10030494649

    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Molecular Structures and Mechanism of Bacterial Nitric Oxide Reductase2012

    • Author(s)
      T. Hino, S. Nagano, H. Sugimoto, T. Tosha, Y. Shiro
    • Journal Title

      Biochim. Biophys. Acta - Bioenergetics

      Volume: 1817 Pages: 680-687

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Proton Transfer in the Quinol-dependent Nitric Oxide Reductase from Geobacillus stearothermophilus during Reduction of Oxygen2012

    • Author(s)
      L. Salomonsson, J. Reimann, T. Tosha, N. Krause, N. Gonska, Y. Shiro, P. Adelroth
    • Journal Title

      Special Issue on Respiratory Oxidases in Biochim

      Volume: Biophys. Acta - Bioenergetics 1817 Pages: 1914-1920

    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] "Structural Basis for Nitrous Oxide Generation by Bacterial Nitric Oxide Reductases" the Proceedings of the Royal Society Meeting2012

    • Author(s)
      Y. Shiro, H. Sugimoto, T. Tosha, S. Nagano, T. Hino
    • Journal Title

      'Nitrous oxide, the forgotten greenhouse gas', Philosophical Transactions B, The Royal Society

      Volume: 367 Pages: 1195-1203

    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Structural Basis for Oxygen Sensing and Signal Transduction of the Heme-Based Sensor Protein Aer2 from Pseudomonas aeruginosa2012

    • Author(s)
      H. Sawai, H. Sugimoto, Y. Shiro, H. Ishikawa, Y. Mizutani, S. Aono
    • Journal Title

      Chem. Commun

      Volume: 48 Issue: 52 Pages: 6523-6525

    • DOI

      10.1039/c2cc32549g

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041, KAKENHI-PROJECT-23350084, KAKENHI-PROJECT-23651086, KAKENHI-PROJECT-24687015, KAKENHI-PROJECT-24770124, KAKENHI-PLANNED-22105012
  • [Journal Article] Interactions of Soluble Guanylate Cyclase with a P-Site Inhibitor: Effects of Gaseous Heme Ligands, Azide, and Allosteric Activators on the Binding of 2'-Deoxy-3'-GMP2012

    • Author(s)
      R. Makino, S. Yazawa, H. Hori, Y. Shiro
    • Journal Title

      Biochemistry

      Volume: 51 Pages: 9277-9289

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Diversity and Substrate Specificity in the Structures of Steroidogenic Cytochrome P450 Enzymes2012

    • Author(s)
      H. Sugimoto, Y. Shiro
    • Journal Title

      Biol. Pharm. Bull.

      Volume: 35 Pages: 818-823

    • NAID

      130001872159

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Molecular Dynamic Simulations Reveal Proton Transfer Pathways in Cytochrome C-Dependent Nitric Oxide Reductase2012

    • Author(s)
      A. V. Pisliakov, T. Hino, Y. Shiro, Y. Sugita
    • Journal Title

      POLS Comp. Biol.

      Volume: 8

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Molecular Structures and Mechanism of Bacterial Nitric Oxide Reductase2012

    • Author(s)
      T. Hino, S. Nagano, H. Sugimoto, T. Tosha, Y. Shiro
    • Journal Title

      Biochim. Biophys. Acta - Bioenergetics

      Volume: 1817 Pages: 680-687

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Interactions of Soluble Guanylate Cyclase with a P-Site Inhibitor: Effects of Gaseous Heme Ligands, Azide, and Allosteric Activators on the Binding of 2’-Deoxy-3’-GMP2012

    • Author(s)
      R. Makino, S. Yazawa, H. Hori, Y. Shiro
    • Journal Title

      Biochemistry

      Volume: 51 Issue: 46 Pages: 9277-9289

    • DOI

      10.1021/bi3004044

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041, KAKENHI-PLANNED-22105012
  • [Journal Article] Structural Basis for Nitrous Oxide Generation by Bacterial Nitric Oxide Reductases2012

    • Author(s)
      Y. Shiro, H. Sugimoto, T. Tosha, S. Nagano, T. Hino
    • Journal Title

      Philosophical Transactions B, The Royal Society

      Volume: 367 Pages: 1195-1203

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Molecular Dynamic Simulations Reveal Proton Transfer Pathways in Cytochrome C-Dependent Nitric Oxide Reductase2012

    • Author(s)
      A. V. Pisliakov, T. Hino, Y. Shiro, Y. Sugita
    • Journal Title

      POLS Comp. Biol.

      Volume: 8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Crystal Structure of Quinol-Dependent Nitric Oxide Reductase from Geobacillus stearithermophilus2012

    • Author(s)
      Y.Matsumoto, T.Tosha, A.V.Pisliakov, T.Hino, H.Sugimoto, S.Nagano, Y.Sugita, Y.Shiro
    • Journal Title

      Nat.Strl.Mol.Biol.

      Volume: 19 Issue: 2 Pages: 238-245

    • DOI

      10.1038/nsmb.2213

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041, KAKENHI-PLANNED-22105012, KAKENHI-PROJECT-22310137, KAKENHI-PROJECT-22770136, KAKENHI-PROJECT-22770163, KAKENHI-PUBLICLY-23121531
  • [Journal Article] "Structure and Function of Bacterial Nitric Oxide Reductases, Anaerobic Enzymes" Special Issue on European BioEnergetic Conference 2012 in Biochim2012

    • Author(s)
      Y. Shiro
    • Journal Title

      Biophys. Acta - Bioenergetics

      Volume: 1817 Pages: 1907-1913

    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Coupling Reaction of Indolepyruvic Acid by StaD and Its Product: Implications of Biosynthesis of Indolocarbazole and Violacein2012

    • Author(s)
      S. Asamizu, S. Hirano, H. Onaka, H. Koshino, Y. Shiro, S. Nagano
    • Journal Title

      ChemBioChem

      Volume: 13 Pages: 2495-2500

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Molecular Structures and Mechanism of Bacterial Nitric Oxide Reductase2012

    • Author(s)
      T. Hino, S. Nagano, H. Sugimoto, T. Tosha, Y. Shiro
    • Journal Title

      Special Issue on Respiratory Oxidases in Biochim

      Volume: Biophys. Acta - Bioenergetics 1817 Pages: 680-687

    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] 一酸化窒素還元酵素の結晶構造から見えてきた呼吸酵素の機能変換2012

    • Author(s)
      日野智也、當舍武彦、城 宜嗣
    • Journal Title

      生物物理

      Volume: Vol 52 Pages: 186-189

    • NAID

      10030494649

    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] 一酸化窒素還元酵素の結晶構造から見えてきた呼吸酵素の機能変換2012

    • Author(s)
      日野智也、當舍武彦、城 宜嗣
    • Journal Title

      生物物理

      Volume: 52 Pages: 186-189

    • NAID

      10030494649

    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Crystal Structure of Quinol-Dependent Nitric Oxide Reductase from Geobacillus Stearothermophilus2012

    • Author(s)
      Y. Matsumoto, T. Tosha, A. V. Pisliakov, T. Hino, H. Sugimoto, S. Nagano, Y. Sugita, Y. Shiro
    • Journal Title

      Nat. Strl. Mol. Biol

      Volume: 19 Pages: 238-245

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Structure and Function of Bacterial Nitric Oxide Reductases, Anaerobic Enzymes2012

    • Author(s)
      Y. Shiro
    • Journal Title

      Biochim. Biophys. Acta - Bioenergetics

      Volume: 1817 Pages: 1917-1913

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Crystal Structure of H2O2-dependent Cytochrome P450SPαwith its Bound Fatty Acid Substrate : Insight into the Regioselective Hydroxylation of Fatty Acids at theαPosition2011

    • Author(s)
      T. Fujishiro, O. Shoji, S. Nagano, H. Sugimoto, Y. Shiro, Y. Watanabe
    • Journal Title

      J. Biol. Chem.

      Volume: 286 Issue: 34 Pages: 29941-29950

    • DOI

      10.1074/jbc.m111.245225

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19105004, KAKENHI-PROJECT-21245041, KAKENHI-PROJECT-21685018, KAKENHI-PLANNED-22105012, KAKENHI-PROJECT-22310137, KAKENHI-PUBLICLY-23121531
  • [Journal Article] Application of Micro-reactor Chip Technique for Millisecond Quenching of Deuterium Incorporation into 70S Ribosomal Protein Complex2011

    • Author(s)
      T.Yamamoto, Y.Shimizu, T.Ueda, Y.Shiro, M.Suematsu
    • Journal Title

      Intl.J.Mass Spectrometry

      Volume: 302 Issue: 1-3 Pages: 132-138

    • DOI

      10.1016/j.ijms.2010.08.029

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] 一酸化窒素還元酵素NOR-呼吸酵素の分子進化と温室効果ガスの産生メカニズム-2011

    • Author(s)
      日野智也、城宜嗣
    • Journal Title

      化学

      Volume: 66 Pages: 30-35

    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Application of Micro-reactor Chip Technique for Millisecond Quenching of Deuterium Incorporation into 70S Ribosomal Protein Complex2011

    • Author(s)
      T.Yamamoto, Y.Shimizu, T.Ueda, Y.Shiro, M.Suematsu
    • Journal Title

      Intl.J.Mass Spectrometry

      Volume: 302 Pages: 132-138

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] 一酸化窒素還元酵素NOR ―呼吸酵素の分子進化と温室効果ガスの産生メカニズム―2011

    • Author(s)
      日野智也、城 宜嗣
    • Journal Title

      化学

      Volume: Vol 66 Pages: 30-35

    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Application of Micro-reactor Chip Technique for Millisecond Quenching of Deuterium Incorporation into 70S Ribosomal Protein Complex2011

    • Author(s)
      T. Yamamoto, Y. Shimizu, T. Ueda, Y. Shiro, M. Suematsu
    • Journal Title

      Intl. J. Mass Spectrometry

      Volume: 302 Pages: 132-138

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Oxygen Binding and Redox Properties of the Heme in Soluble Guanylate Cyclase : Implications for the Mechanism of Ligand Discrimination2011

    • Author(s)
      R. Makino, S.-Y. Park, E. Obayashi, T. Iizuka, H. Hori, Y. Shiro
    • Journal Title

      J. Biol. Chem

      Volume: 286 Pages: 15678-15687

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Structural Basis of Biological N_20 Generation by Bacterial Nitric Oxide Reductase2011

    • Author(s)
      Hino, T., Matsumoto, Y., Nagano, S., Sugimoto, H., Fukumori, Y., Murata, T., Iwata, S., Shiro, Y.
    • Journal Title

      Science 330

      Pages: 1666-1670

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310147
  • [Journal Article] Crystal Structure of Carbonmonoxide Complex of Human Cytoglobin2011

    • Author(s)
      M. Makino, H. Sawai, Y. Shiro, H. Sugimoto
    • Journal Title

      PROTEINS

      Volume: 79 Pages: 1143-1153

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Crystal Structure of Carbonmonoxide Complex of Human Cytoglobin2011

    • Author(s)
      M.Makino, H.Sawai, Y.Shiro, H.Sugimoto
    • Journal Title

      PROTEINS

      Volume: 79 Issue: 4 Pages: 1143-1153

    • DOI

      10.1002/prot.22950

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22105012, KAKENHI-PROJECT-22870043
  • [Journal Article] Oxygen Binding and Redox Properties of the Heme in Soluble Guanylate Cyclase : Implications for the Mechanism of Ligand Discrimination2011

    • Author(s)
      R.Makino, S.-Y.Park, E.Obayashi, T.Iizuka, H.Hori, Y.Shiro
    • Journal Title

      J.Biol.Chem.

      Volume: 286 Issue: 18 Pages: 15678-15687

    • DOI

      10.1074/jbc.m110.177576

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Characterization and Functional Modification of StaC and RebC, Which are Involved in Pyrrole Oxidation of Indolocarbazole Biosynthesis2011

    • Author(s)
      S. Asamizu, Y. Shiro, Y. Igarashi, S. Nagano, H. Onaka
    • Journal Title

      Biosci. Biotechnol. Biochem

      Volume: 75 Pages: 2184-2193

    • NAID

      10030396835

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] 一酸化窒素還元酵素NOR-呼吸酵素の分子進化と温室効果ガスの産生メカニズム-2011

    • Author(s)
      日野智也、城宜嗣
    • Journal Title

      化学

      Volume: 66 Pages: 30-35

    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Oxygen Binding and Redox Properties of the Heme in Soluble Guanylate Cyclase : Implications for the Mechanism of Ligand Discrimination2011

    • Author(s)
      R.Makino, S.-Y.Park, E.Obayashi, T.Iizuka, H.Hori, Y.Shiro
    • Journal Title

      J.Biol.Chem.

      Volume: 286 Pages: 15678-15687

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Crystal Structure of H_2O_2-dependent Cytochrome P450_<SPa> with Its Bound Fatty Acid Substrate: Insight into the Regioselective Hydroxylation of Fatty Acids at the a Position2011

    • Author(s)
      T. Fujishiro, O. Shoji, S. Nagano, H. Sugimoto, Y. Shiro, Y. Watanabe
    • Journal Title

      J. Biol. Chem

      Volume: 286 Pages: 29941-29950

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Resonance Raman study on the oxygenated and the ferryl-oxo species of indoleamine 2,3-dioxygenase during catalytic turnover2011

    • Author(s)
      S. Yanagisawa, M. Horitani, H. Sugimoto, Y. Shiro, N. Okada, T. Ogura
    • Journal Title

      Faraday Discuss

      Volume: 1814 Pages: 249-256

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Design of Novel Hypoxia-targeting IDO Hybrid Inhibitors Conjugated with an Unsubstituted L-TRP as an IDO Affinity Moiety2010

    • Author(s)
      H.Nakashima, K.Ikkyu, K.Nakashima, K.Sano, Y.Uto, E.Nakata, H.Nagasawa, H.Sugimoto, Y.Shiro, Y.Nakagawa, H.Hori
    • Journal Title

      Adv.Exp.Med.Biol.

      Volume: 662

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Three-step Hydroxylations of Vitamin D_3 by a Genetically Engineered CYP105A12010

    • Author(s)
      K. Hayashi, K. Yasuda, H. Sugimoto, S. Ikushiro, M. Kamakura, A. Kittaka, R. Horst, T. Chen, M. Ohta, Y. Shiro, T. Sakaki
    • Journal Title

      FEBS Lett

      Volume: 277 Pages: 3999-4009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Understanding Substrate Misrecognition of Hydrogen Peroxide-Dependent Cytochrome P450 from Bacillus subtilis2010

    • Author(s)
      O.Shoji, T.Fujishiro, S.Nagano, S.Tanaka, T.Hirose, Y.Shiro, Y.Watanabe
    • Journal Title

      J.Bio.Inorg.Chem.

      Volume: 15 Pages: 1331-1339

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] ONIOM Study on a Missing Piece in Our Understanding of Heme Chemistry : Bacterial Tryptophan 2,3-Dioxygenase with Dual Oxidants2010

    • Author(s)
      L.W.Chung, X.Li, H.Sugimoto, Y.Shiro, K.Morokuma
    • Journal Title

      J.Am.Chem.Soc.

      Volume: 132 Pages: 11993-12005

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Structural Basis of Biological N_2O Generation by Bacterial Nitric Oxide Reductase2010

    • Author(s)
      T.Hino, Y.Matsumoto, S.Nagano, H.Sugimoto, Y.Fukumori, T.Murata, S.Iwata, Y.Shiro
    • Journal Title

      Science

      Volume: 330 Pages: 1666-1670

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] ONIOM Study on a Missing Piece in Our Understanding of Heme Chemistry : Bacterial Tryptophan 2,3-Dioxygenase with Dual Oxidants2010

    • Author(s)
      L.W.Chung, X.Li, H.Sugimoto, Y.Shiro, K.Morokuma
    • Journal Title

      J.Am.Chem.Soc.

      Volume: 132 Pages: 11993-12005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Unique Properties and reactivity of High-Valent Manganese-Oxo versus Manganese-Hydroxo in the Salen Platform2010

    • Author(s)
      T.Kurahashi, A.Kikuchi, Y.Shiro, M.Hada, H.Fujii
    • Journal Title

      Inorg.Chem.

      Volume: 49 Pages: 6664-6672

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Understanding substrate misrecognition of hydrogen peroxide dependent cytochrome P450 from Bacillus subtilis2010

    • Author(s)
      Shoji, O., Fujishiro, T., Nagano, S., Tanaka, S., Hirose, T., Shiro, Y., Watanabe, Y.
    • Journal Title

      J.Biol.Inorg.Chem. 2010, 15

      Pages: 1331-1339

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310147
  • [Journal Article] Design of Novel Hypoxia-targeting IDO Hybrid Inhibitors Conjugated with an Unsubstituted L-TRP as an IDO Affinity Moiety2010

    • Author(s)
      H.Nakashima, K.Ikkyu, K.Nakashima, K.Sano, Y.Uto, E.Nakata, H.Nagasawa, H.Sugimoto, Y.Shiro, Y.Nakagawa, H.Hori
    • Journal Title

      Adv.Exp.Med.Biol.

      Volume: 662 Pages: 415-421

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] A Specific Interaction of L-Tryptophan with CO of CO-Bound Indoleamine 2,3-Dioxygenase Identified by Resonance Raman Spectroscopy2010

    • Author(s)
      S.Yanagisawa, H.Sugimoto, Y.Shiro, T.Ogura
    • Journal Title

      Biochemistry

      Volume: 49 Pages: 10081-10088

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] ONIOM Study on a Missing Piece in Our Understanding of Heme Chemistry: Bacterial Tryptophan 2,3-Dioxygenase with Dual Oxidants2010

    • Author(s)
      L. W. Chung, X. Li, H. Sugimoto, Y. Shiro, K. Morokuma
    • Journal Title

      J. Am. Chem. Soc

      Volume: 132 Pages: 11993-12005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Understanding Substrate Misrecognition of Hydrogen Peroxide-Dependent Cytochrome P450 from Bacillus subtilis2010

    • Author(s)
      O. Shoji, T. Fujishiro, S. Nagano, S. Tanaka, T. Hirose, Y. Shiro, Y. Watanabe
    • Journal Title

      J. Bio. Inorg. Chem

      Volume: 15 Pages: 1331-1339

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Understanding Substrate Misrecognition of Hydrogen Peroxide-Dependent Cytochrome P450 from Bacillus subtilis2010

    • Author(s)
      O.Shoji, T.Fujishiro, S.Nagano, S.Tanaka, T.Hirose, Y.Shiro, Y.Watanabe
    • Journal Title

      J.Bio.Inorg.Chem.

      Volume: 15 Pages: 1331-1339

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Three-step Hydroxylations of Vitamin D_3 by a Genetically Engineered CYP105A12010

    • Author(s)
      K.Hayashi, K.Yasuda, H.Sugimoto, S.Ikushiro, M.Kamakura, A.Kittaka, R.Horst, T.Chen, M.Ohta, Y.Shiro, T.Sakaki
    • Journal Title

      FEBS Lett.

      Volume: 277 Pages: 3999-4009

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Bioconversion of Vitamin D to Its Active Form by Bacterial or Mamalian Cytochromes P4502010

    • Author(s)
      T.Sakaki, H.Sugimoto, K.Hayashi, K.Yasuda, E.Munetsna, M.Kamakura, S.Ikushiro, Y.Shiro
    • Journal Title

      Biochim.Biophys.Acta

      Volume: 1814 Pages: 249-256

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Excited States of Fluorescent Proteins, mKO and DsRed: Chromophore-protein Electrostatic Interaction Behind the Color Variations2010

    • Author(s)
      J. Hasegawa, Y. Ise, K. Fujimoto, A. Kikuchi, E. Fukumura, A. Miyawaki, Y. Shiro
    • Journal Title

      J. Phys. Chem

      Volume: B 114 Pages: 2971-2979

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Bioconversion of Vitamin D to Its Active Form by Bacterial or Mammalian Cytochromes P4502010

    • Author(s)
      T. Sakaki, H. Sugimoto, K. Hayashi, K. Yasuda, E. Munetsna, M. Kamakura, S. Ikushiro, Y. Shiro
    • Journal Title

      Biochim. Biophys. Acta

      Volume: 1814 Pages: 249-256

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] A novel Glycerophosphodiester Phosphodiesterase GDE5 Controls Skeletal Muscle Development via a Non-enzymatic Mechanism2010

    • Author(s)
      Y.Okazaki, N.Ohshima, I.Yoshizawa, Y.Kamei, S.Mariggio, K.Okamoto, M.Maeda, Y.Nogusa, Y.Fujioka, T.Izumi, Y.Ogawa, Y.Shiro, M.Wada, N.Kato, D.Corda, N.Yanaka
    • Journal Title

      J.Biol.Chem.

      Volume: 285 Pages: 27652-27663

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Design of Novel Hypoxia-targeting IDO Hybrid Inhibitors Conjugated with an Unsubstituted L-TRP as an IDO Affinity Moiety2010

    • Author(s)
      H. Nakashima, K. Ikkyu, K. Nakashima, K. Sano, Y. Uto, E. Nakata, H. Nagasawa, H. Sugimoto, Y. Shiro, Y. Nakagawa, H. Hori
    • Journal Title

      Adv. Exp. Med. Biol

      Volume: 662 Pages: 415-421

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Structural Basis of Biological N_2O Generation by Bacterial Nitric Oxide Reductase2010

    • Author(s)
      T.Hino, Y.Matsumoto, S.Nagano, H.Sugimoto, Y.Fukumori, T.Murata, S.Iwata, Y.Shiro
    • Journal Title

      Science

      Volume: 330 Pages: 1666-1670

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] A Specific Interaction of L-Tryptophan with CO of CO-Bound Indoleamine 2,3-Dioxygenase Identified by Resonance Raman Spectroscopy2010

    • Author(s)
      S. Yanagisawa, H. Sugimoto, Y. Shiro, T. Ogura
    • Journal Title

      Biochemistry

      Volume: 49 Pages: 10081-10088

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Three-step Hydroxylations of Vitamin D_3 by a Genetically Engineered CYP105A12010

    • Author(s)
      K.Hayashi, K.Yasuda, H.Sugimoto, S.Ikushiro, M.Kamakura, A.Kittaka, R.Horst, T.Chen, M.Ohta, Y.Shiro, T.Sakaki
    • Journal Title

      FEBS Lett.

      Volume: 277 Pages: 3999-4009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Bioconversion of Vitamin D to Its Active Form by Bacterial or Mammalian Cytochromes P4502010

    • Author(s)
      T.Sakaki, H.Sugimoto, K.Hayashi, K.Yasuda, E.Munetsna, M.Kamakura, S.Ikushiro, Y.Shiro
    • Journal Title

      Biochim.Biophys.Acta

      Volume: 1814 Pages: 249-256

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] A novel Glycerophosphodiester Phosphodiesterase GDE5 Controls Skeletal Muscle Development via a Non-enzymatic Mechanism2010

    • Author(s)
      Y.Okazaki, N.Ohshima, I.Yoshizawa, Y.Kamei, S.Mariggio, K.Okamoto, M.Maeda, Y.Nogusa, Y.Fujioka, T.Izumi, Y.Ogawa, Y.Shiro, M.Wada, N.Kato, D.Corda, N.Yanaka
    • Journal Title

      J.Biol.Chem.

      Volume: 285 Pages: 27652-27663

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Journal Article] Unique Properties and reactivity of High-Valent Manganese-Oxo versus Manganese-Hydroxo in the Salen Platform2010

    • Author(s)
      T. Kurahashi, A. Kikuchi, Y. Shiro, M. Hada, H. Fujii
    • Journal Title

      Inorg. Chem

      Volume: 49 Pages: 6664-6672

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Unique Properties and reactivity of High-Valent Manganese-Oxo versus Manganese-Hydroxo in the Salen Platform2010

    • Author(s)
      T.Kurahashi, A.Kikuchi, Y.Shiro, M.Hada, H.Fujii
    • Journal Title

      Inorg.Chem.

      Volume: 49 Pages: 6664-6672

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Mg^<2+> Dependence of 70S Ribosomal Protein Flexibility Revealed by Hydrogen/Deuterium Exchange and Mass Spectrometry2010

    • Author(s)
      T. Yamamoto, Y. Shimizu, T. Ueda, Y. Shiro
    • Journal Title

      J. Biol. Chem

      Volume: 285 Pages: 5646-5652

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Structural Basis of Biological N2O Generation by Bacterial Nitric Oxide Reductase2010

    • Author(s)
      T. Hino, Y. Matsumoto, S. Nagano, H. Sugimoto, Y. Fukumori, T. Murata, S. Iwata, Y. Shiro
    • Journal Title

      Science

      Volume: 330 Pages: 1666-1670

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] A novel Glycerophosphodiester Phosphodiesterase GDE5 Controls Skeletal Muscle Development via a Non-enzymatic Mechanism2010

    • Author(s)
      Y. Okazaki, N. Ohshima, I. Yoshizawa, Y. Kamei, S. Mariggio, K. Okamoto, M. Maeda, Y. Nogusa, Y. Fujioka, T. Izumi, Y. Ogawa, Y. Shiro, M. Wada, N. Kato, D. Corda, N. Yanaka
    • Journal Title

      J. Biol. Chem

      Volume: 285 Pages: 27652-27663

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Crystal Structure of a New Cyan Fluorescent Protein and Its Blue-shifted Variants2009

    • Author(s)
      A. Kikuchi, E. Fukumura, S. Karasawa, Y. Shiro, A. Miyawaki
    • Journal Title

      Biochemistry

      Volume: 48 Pages: 5276-5283

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Identification of the Fe-O_2 and the Fe=O Heme Species for Indoleamine 2, 3-Dioxygenase during Catalytic Turnover2009

    • Author(s)
      S.Yanagisawa, K.Yotsuya, Y.Hashiwaki, M.Horitani, H.Sugimoto, Y.Shiro, T.Ogura
    • Journal Title

      Chem.Lett. 39

      Pages: 36-37

    • NAID

      10027176398

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Journal Article] Mg^<2+> Dependence of 70S Ribosomal Protein Flexibility Revealed by Hydrogen/Deuterium Exchange and Mass Spectrometry2009

    • Author(s)
      T.Yamamoto, Y.Shimizu, T.Ueda, Y.Shiro
    • Journal Title

      J.Biol.Chem.

      Volume: 285 Pages: 5646-5652

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] X-ray Crystal Structure of the Michaelis Complex of Aldoxime Dehydratase2009

    • Author(s)
      H.Sawai, H.Sugimoto, Y.Kato, Y.Asano, Y.Shiro, S.Aono
    • Journal Title

      J.Biol.Chem. 284

      Pages: 32089-32096

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Journal Article] X-ray Crystal Structure of the Michaelis Complex of Aldoxime Dehydratase2009

    • Author(s)
      H.Sawai, H.Sugimoto, Y.Kato, Y.Asano, Y.Shiro, S.Aono
    • Journal Title

      J.Biol.Chem.

      Volume: 284 Pages: 32089-32096

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Ligand Energy Controls the Heme-Fe Valence in Aqueous Myoglobins2009

    • Author(s)
      Y. Harada, M. Taguchi, Y. Miyajima, T. Tokushima, Y. Horikawa, A. Chainani, Y. Shiro, Y. Senba, H. Ohashi, H. Fukuyama, S. Shin
    • Journal Title

      J. Phys. Soc. Jpn

      Volume: 78

    • NAID

      10025959931

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Structure of PAS-linked Histidine Kinase and the Response Regulator Complex2009

    • Author(s)
      S.Yamada, H.Sugimoto, M.Kobayashi, A.Ohno, H.Nakamura, Y.Shiro
    • Journal Title

      Structure 17

      Pages: 1333-1344

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Journal Article] Ligand Energy Controls the Heme-Fe Valence in Aqueous Myoglobins2009

    • Author(s)
      Y.Harada, M.Taguchi, Y.Miyajima, T.Tokushima, Y.Horikawa, A.Chainani, Y.Shiro, Y.Senba, H.Ohashi, H.Fukuyama, S.Shin
    • Journal Title

      J.Phys.Soc.Jpn.

      Volume: 78

    • NAID

      10025959931

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Crystal Structure of a New Cyan Fluorescent Protein and Its Hue-shifted Variants2009

    • Author(s)
      A.Kikuchi, E.Fukumura, S.Karasawa, Y.Shiro, A.Miyawaki
    • Journal Title

      Biochemistry

      Volume: 48 Pages: 5276-5283

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Identification of the Fe-O2 and the Fe=O Heme Species for Indoleamine 2,3-Dioxygenase during Catalytic Turnover2009

    • Author(s)
      S.Yanagisawa, K.Yotsuya, Y.Hashiwaki, M.Horitani, H.Sugimoto, Y.Shiro, E.H.Appelman, T.Ogura
    • Journal Title

      Chem.Lett.

      Volume: 39 Pages: 36-37

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Crystal Structure of a New Cyan Fluorescent Protein and Its Hue-shifted Variants2009

    • Author(s)
      A.Kikuchi, E.Fukumura, S.Karasawa, Y.Shiro, A.Miyawaki
    • Journal Title

      Biochemistry 48

      Pages: 5276-5283

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Journal Article] Theoretical and Experimental Studies of the Conversion of Chromopyrrolic Acid to an Antitumor Derivative by Cytochrome P450 StaP : The Biological Role of Water Molecules2009

    • Author(s)
      Wang, Y., Chen, H., Makino, M., Shiro, Y., Na ang o, S., Asamizu, S., Onaka, H., Sason, S.
    • Journal Title

      J. Am.Chem.Soc 131

      Pages: 6748-6762

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310147
  • [Journal Article] Theoretical and Experimental Studies of the Conversion of Chromopyrrolic Acid to an Antitumor Derivative by Cytochrome P450 StaP : The Biological Role of Water Molecules2009

    • Author(s)
      Y.Wang, H.Chen, M.Makino, Y.Shiro, S.Nagano, S.Asamizu, H.Onaka, S.Sason
    • Journal Title

      J.Am.Chem.Soc. 131

      Pages: 6748-6762

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Journal Article] Theoretical and Experimental Studies of the Conversion of Chromopyrrolic Acid to an Antitumor Derivative by Cytochrome P450 StaP: The Biological Role of Water Molecules2009

    • Author(s)
      Y. Wang, H. Chen, M. Makino, Y. Shiro, S. Nagano, S. Asamizu, H. Onaka, S. Sason
    • Journal Title

      J. Am. Chem. Soc

      Volume: 131 Pages: 6748-6762

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Cooperative Binding of L-Trp to Human Tryptophan 2,3-Dioxygenase : Resonance Raman Spectroscopic Analysis2009

    • Author(s)
      E.Fukumura, H.Sugimoto, Y.Misumi, T.Ogura, Y.Shiro
    • Journal Title

      J.Biochem.

      Volume: 145 Pages: 505-515

    • NAID

      10026302198

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Excited States of Fluorescent Proteins, mKO and DsRed : Chromophore-protein Electrostatic Interaction Behind the Color Variations2009

    • Author(s)
      J.Hasegawa, Y.Ise, K.Fujimoto, A.Kikuchi, E.Fukumura, A.Miyawaki, Y.Shiro
    • Journal Title

      J.Phys.Chem.B

      Volume: 114 Pages: 2971-2979

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Cooperative Binding of L-Trp to Human Tryptophan 2,3-Dioxygenase : Resonance Raman Spectroscopic Analysis2009

    • Author(s)
      E.Fukumura, H.Sugimoto, Y.Misumi, T.Ogura, Y.Shiro
    • Journal Title

      J.Biochem. 145

      Pages: 505-515

    • NAID

      10026302198

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Journal Article] Theoretical and Experimental Studies of the Conversion of Chromopyrrolic Acid to an Antitumor Derivative by Cytochrome P450 StaP : The Biological Role of Water Molecules2009

    • Author(s)
      Y.Wang, H.Chen, M.Makino, Y.Shiro, S.Nagano, S.Asamizu, H.Onaka, S.Sason
    • Journal Title

      J.Am.Chem.Soc.

      Volume: 131 Pages: 6748-6762

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] X-ray Crystal Structure of the Michaelis Complex of Aldoxime Dehydratase2009

    • Author(s)
      H. Sawai, H. Sugimoto, Y. Kato, Y. Asano, Y. Shiro, S. Aono
    • Journal Title

      J. Biol. Chem

      Volume: 284 Pages: 32089-32096

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Heme-dependent Autophosphorylation of a Heme Sensor Kinase, ChrS from Corynebacterium diphtheriae Reconstituted in Proteoliposomes2009

    • Author(s)
      Y. Ito, S. Nakagawa, A. Komagata, M. Ikeda-Saito, Y. Shiro, H. Nakamura
    • Journal Title

      FEBS Lett

      Volume: 583 Pages: 2244-2248

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Identification of the Fe-O_2 and the Fe=O Heme Species for Indoleamine 2,3-Dioxygenase during Catalytic Turnover2009

    • Author(s)
      S. Yanagisawa, K. Yotsuya, Y. Hashiwaki, M. Horitani, H. Sugimoto, Y. Shiro, E. H. Appelman, T. Ogura
    • Journal Title

      Chem. Lett

      Volume: 39 Pages: 36-37

    • NAID

      10027176398

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Ligand Energy Controls the Heme-Fe Valence in Aqueous Myoglobins2009

    • Author(s)
      Y.Harada, M.Taguchi, Y.Miyajima, T.Tokushima, Y.Horikawa, A.Chainani, Y.Shiro, Y.Senba, H.Ohashi, H.Fukuyama, S.Shin
    • Journal Title

      J.Phys.Soc.Jpn. 78

    • NAID

      10025959931

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Journal Article] Structure of PAS-linked Histidine Kinase and the Response Regulator Complex2009

    • Author(s)
      S. Yamada, H. Sugimoto, M. Kobayashi, A. Ohno, H. Nakamura, Y. Shiro
    • Journal Title

      Structure

      Volume: 17 Pages: 1333-1344

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Cooperative Binding of L-Trp to Human Tryptopahn 2, 3-Dioxygenase : Resonanace Raman Spectroscopic Analysis2009

    • Author(s)
      E.Fukumura, H.Sugimoto, Y.Misumi, T.Ogura.Y.Shiro
    • Journal Title

      J.Biochem. (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Journal Article] Heme-dependent Autophosphorylation of a Heme Sensor Kinase, ChrS from Corynebacterium diphtheriae Reconstituted in Proteoliposomes2009

    • Author(s)
      Y.Ito, S.Nakagawa, A.Komagata, M.Ikeda-Saito, Y.Shiro, H.Nakamura
    • Journal Title

      FEBS Lett. 583

      Pages: 2244-2248

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Journal Article] Heme-dependent Autophosphorylation of a Heme Sensor Kinase, ChrS from Corynebacterium diphtheriae Reconstituted in Proteoliposomes2009

    • Author(s)
      Y.Ito, S.Nakagawa, A.Komagata, M.Ikeda-Saito, Y.Shiro, H.Nakamura
    • Journal Title

      FEBS Lett.

      Volume: 583 Pages: 2244-2248

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Cooperative Binding of L-Trp to Human Tryptophan 2,3-Dioxygenase: Resonance Raman Spectroscopic Analysis2009

    • Author(s)
      E. Fukumura, H. Sugimoto, Y. Misumi, T. Ogura, Y. Shiro
    • Journal Title

      J. Biochem

      Volume: 145 Pages: 505-515

    • NAID

      10026302198

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Journal Article] Separation of phosphoprotein isotypes having the same number of phosphate groups using phosphate-affinity SDS-PAGE2008

    • Author(s)
      E.Kinoshita, E.Kinoshita-Kikuta, M.Matsubara, S.Yamada, H.Nakamura, Y.Shiro, Y.Aoki, K.Okita, T.Koike
    • Journal Title

      Proteomics 8

      Pages: 2994-3003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Journal Article] Crystal structure of VioE, a key player in the construction of the molecular skeleton of violacein2008

    • Author(s)
      Hirano, S., Asamizu, S., Onaka, H., Shiro, Y., Nagano, S.
    • Journal Title

      J.Biol.Chem. 283

      Pages: 6459-6466

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310147
  • [Journal Article] Purification and functional characterization of human 11βhydroxylase expressed in E. coli.2008

    • Author(s)
      Shiro, Y. (8名中6番目)
    • Journal Title

      FEBS J. 275

      Pages: 799-810

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17GS0221
  • [Journal Article] Crystal Structure of CYP105A1(P450SU-1) in Complex with 1a, 25-dihydroxyvitamin D_32008

    • Author(s)
      H.Sugimoto, R.Shinkyo, K.Hayashi, S.Yoneda, M.Yamada, M.Kamakura, S, Ikushiro, Y.Shiro, T.Sakaki
    • Journal Title

      Biochemistry 47

      Pages: 4017-4027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Journal Article] Crystal Structure of VioE, a Key Player in the Construction of the Molecular Skelton of Violacein2008

    • Author(s)
      S.Hirano, S.Asamizu, H.Onaka, Y.Shiro, S.Nagano
    • Journal Title

      J.Biol.Chem. 283

      Pages: 6459-6466

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Journal Article] Crystal structure of CYP105A1 (P450SU-1) in complex with 1α2008

    • Author(s)
      Shiro, Y. (9名中8番目)
    • Journal Title

      25-dihydroxyvitamin D3., Biochemistry 47

      Pages: 4017-4027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17GS0221
  • [Journal Article] Molecular Design of Heteroprotein Assmblies Providing a Bionanocup as a Chemical Reactor2008

    • Author(s)
      T.Koshiyama, N.Yokoi, T.Ueno, S.Kanamaru, S.Nagano, Y.Shiro, F.Arisaka, Y.Watanabe
    • Journal Title

      Small 4

      Pages: 50-54

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Journal Article] Purification and Functional Characterization of Human 11b Hydroxylace Expressed in E.coli2008

    • Author(s)
      A.Zoellner, N.Kagawa, M.R.Waterman, Y.Nonaka, K.Takio, Y.Shiro, F.Hannemann, R.Bernhardt
    • Journal Title

      FEBS J. 275

      Pages: 799-810

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Journal Article] Molecular design of heteroprotein assemblies providing a bionanocup as a chemical reactor2008

    • Author(s)
      Koshiyama, T., Yokoi, N., Ueno, T., Kanamaru, S., Nagano, S., Shiro, Y., Arisaka, F., Watanabe, Y.
    • Journal Title

      Small 4

      Pages: 50-54

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310147
  • [Journal Article] Density Functional Theory Study on a MIssing Piece in Understanding of Heme Chemistry : The Reaction Mechanism Fro Indoleamine 2, 3-dioxygenase and Typtophan 2, 3-dioxygenase2008

    • Author(s)
      L.W.Chung, X.Li, H.Sugimoto, Y.Shiro, K.Morokuma
    • Journal Title

      J.Am.Chem.Soc. 130

      Pages: 12299-12309

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Journal Article] New insights into chemical biology from ORFeome libraries.2008

    • Author(s)
      Yashiroda Y., et. al.
    • Journal Title

      Curr. Opin. Chem. Biol. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17GS0221
  • [Journal Article] Synthesis and Biological Activity of 1-methyl-tryptophan-tirapazamine Hybrids hypoxia-targeting Indoleamine 2, 3-dioxygenase inhibitors2008

    • Author(s)
      H.Nakashima, Y.Uto, E.Nakata, H.Nagasawa, K.Ikkyu, N.Hiraoka, K.Nakashima, Y.Sasaki, H.Sugimoto, Y.Shiro, T.hashimoto, Y.Okamoto, Y.Asakawa, H.Hori :
    • Journal Title

      Bioorg.Med.Chem. 16

      Pages: 8661-8669

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Journal Article] Crystal structure of VioE, a key player in the construction of the molecular skelton of violacein.2008

    • Author(s)
      Shiro, Y. (5名中4番目)
    • Journal Title

      J. Biol. Chem. 283

      Pages: 6459-6466

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17GS0221
  • [Journal Article] Sturucture-based Design of a Highly Active Vitamin D Hydroxylase from Streptomyces griseolus CYP105A12008

    • Author(s)
      K.Hayashi, H.Sugimoto, R.Shinkyo, M.Yamada, S.Ikeda, S.Ikushiro, M.Kamakura, Y.Shiro, T.sasaki
    • Journal Title

      Biochemistry 47

      Pages: 11964-11972

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Journal Article] Separation of a Phosphorylated Histidine Protein Using Phosphate Affinity Polyacrlamide Gel Electrophoresis2007

    • Author(s)
      S.Yamada, H.Nakamura, E.Kinoshita, E.Kinoshita-Kikuta, T.Koike, Y.Shiro
    • Journal Title

      Anal. Biochem. 360

      Pages: 160-162

    • Data Source
      KAKENHI-PROJECT-16074217
  • [Journal Article] Crystal structures and catalytic mechanism of cytochrome P450 StaP that produces the indolocarbazole skeleton2007

    • Author(s)
      Makino, M., Sugimoto, H., Shiro, Y., Asamizu, S., Onaka, H., Nagano, S.
    • Journal Title

      Proc.Natl.Acad.Sci.U.S.A. 104

      Pages: 11591-11596

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310147
  • [Journal Article] Hydrogen peroxide dependent monooxygenations by tricking the substrate recognition of cytochrome P450(BSβ)2007

    • Author(s)
      Shoji, O., Fujishiro, T., Nakajima, H., Kim, M., Nagano, S., Shiro, Y., Watanabe, Y.
    • Journal Title

      Angew.Chem.Int Ed. 46

      Pages: 656-3659

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310147
  • [Journal Article] Crystal Structures and Catalytic Mechanism of Cytochrome P450 StaP That Produces The Indolocarbazole Skeleton2007

    • Author(s)
      H. Makino, H. Sugimoto, Y. Shiro, S. Asamizu, H. Onaka, S. Nagano
    • Journal Title

      Proc. Natl. Acad. Sci. USA 104

      Pages: 11591-11596

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16074217
  • [Journal Article] Crystal Structures and Catalytic Mechanism of Cytochrome P450 StaP That Produces The Indolocarbazole Skeleton2007

    • Author(s)
      M. Makino, H. Sugimoto, Y. Shiro, S. Asamizu, H. Onaka, S. Nagano
    • Journal Title

      Proc. Natl. Acad. Sci. USA 104

      Pages: 11591-11596

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16074217
  • [Journal Article] Crystal Structure of Human Indoleamine 2,3-dioxygenase : Insight into the Catalytic Mechanism of O_2 Incorporation by a Heme-containing Dioxygenase2006

    • Author(s)
      H.Sugimoto, S.Oda, T.Otsuki, T.Hino, T.Yoshida, Y.Shiro
    • Journal Title

      Poc.Natl.Acd.Sci.USA 103

      Pages: 2611-2616

    • Data Source
      KAKENHI-PROJECT-16074217
  • [Journal Article] Crystal structure of human indoleamine 2, 3-dioxygenase: insight into the catalytic mechanism of O2 incorporation by a hemecontaining dioxygenase.2006

    • Author(s)
      Shiro, Y. (6名中6番目)
    • Journal Title

      Proc. Natl. Acad. Sci. USA 103

      Pages: 2611-2616

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17GS0221
  • [Journal Article] High-resolution Structure of Human Cytoglobin : Identification of Extra N- and C-termini and a New Dimerization Mode2006

    • Author(s)
      M.Makino, H.Sugimoto, H.Sawai, N.Kawada, K.Yoshizato, Y.Shiro
    • Journal Title

      Acta Cryst. D62

      Pages: 671-677

    • Data Source
      KAKENHI-PROJECT-16074217
  • [Journal Article] Crystal Structure of Human Indoleamine 2, 3-dioxygenase : Insight into the Catalytic Mechanism of 02 Incorporation by a Heme-containing Dioxygenase2006

    • Author(s)
      H. Sugimoto, S. Oda, T. Otsuki, T. Hino, T. Yoshida, Y. Shiro
    • Journal Title

      Proc. Natl. Acad. Sci. USA 103

      Pages: 2611-2616

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16074217
  • [Journal Article] The Signaling Pathway in Histidine Kinase and the Response Regulator Complex Revealed by X-ray Crystallography and Solution Scattering2006

    • Author(s)
      S. Yamada, S. Akiyama, H. Sugimoto, H. Kumita, K. Ito, T. Fujisawa, H. Nakamura, Y. Shiro
    • Journal Title

      J. Mol. Biol. 362

      Pages: 123-139

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16074217
  • [Journal Article] Crystal Structure of Human Indoleamine 2, 3-dioxygenase : Insight into the Catalytic Mechanism of O_2 Incorporation by a Heme-containing Dioxygenase2006

    • Author(s)
      H.Sugimoto, S.Oda, T.Otsuki, T.Hino, T.Yoshida, Y.Shiro
    • Journal Title

      Poc. Natl. Acd. Sci. USA 103

      Pages: 2611-2616

    • Data Source
      KAKENHI-PROJECT-16074217
  • [Journal Article] Crystal Structure of Human Indoleamine 2, 3-dioxygenase : Insight into the Catalytic Mechanism of 02 Incorporation by a Heme-containing Dioxygenase2006

    • Author(s)
      H. Sugimoto, S. Oda, T. Otsuki, T. HIno, T. Yoshida, Y. Shiro
    • Journal Title

      Proc. Natl. Acad. Sci. USA 103

      Pages: 2611-2616

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16074217
  • [Journal Article] Purification, Crystallization and Preliminary X-ray Crystallographic Study of the L-Fucculose-1-phosphate Aldolase (FucA) from Thermus thermophilus HB82006

    • Author(s)
      J.Jeyakanthan, J.Taka, A.Kikuchi, C.Kuroishi, K.Yutani, Y.Shiro
    • Journal Title

      Acta Cryst. F61

      Pages: 1075-1077

    • Data Source
      KAKENHI-PROJECT-16074217
  • [Journal Article] 酸素添加酵素の分子メカニズム2006

    • Author(s)
      杉本 宏, 永野真吾, 城 宜嗣
    • Journal Title

      日本結晶学会誌 48

      Pages: 418-423

    • NAID

      10018467419

    • Data Source
      KAKENHI-PROJECT-16074217
  • [Journal Article] The Signaling Pathway in Histidine Kinase and the Response Regulator Complex Revealed by X-ray Crystallography and Solution Scattering2006

    • Author(s)
      S.Yamada, S.Akiyama, H.Sugimoto, H.Kumita, K.Ito, T.Fujisawa, H.Nakamura, Y.Shiro
    • Journal Title

      J. Mol. Biol. 362

      Pages: 123-139

    • Data Source
      KAKENHI-PROJECT-16074217
  • [Journal Article] Crystallization and Preliminary Crystallographic Studies of Human Indoleamine 2, 3-Dioxygenase2006

    • Author(s)
      S.Oda, H.Sugimoto, T.Yoshida, Y.Shiro
    • Journal Title

      Acta Cryst. F62

      Pages: 221-223

    • Data Source
      KAKENHI-PROJECT-16074217
  • [Journal Article] Roles of the Heme Distal Residues of FixL in O_2 Sensing : A Single Convergent Structure of the Heme Moiety is Relevant to the Down-regulation of Kinase Activity2006

    • Author(s)
      A.Tanaka, H.Nakamura, Y.Shiro, H.Fujii
    • Journal Title

      Biochemistry 45

      Pages: 2515-2523

    • Data Source
      KAKENHI-PROJECT-16074217
  • [Journal Article] The Signaling Pathway in Histidine Kinase and the Response Regulator Complex Revealed by X-ray Crystallography and Solution Scattering2006

    • Author(s)
      S. Yamada, S. Akiyama, H. Sugimoto, H. Kumita. K. Ito, T Fujisawa, H. Nakamura, Y. Shiro
    • Journal Title

      J. Mol. Biol. 362

      Pages: 123-139

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16074217
  • [Journal Article] De Novo Design of the λCro Fold and Experimental Determination of its Monomeric Solution Structure2005

    • Author(s)
      Y.Isogai, Y.Ito, T.Ikeya, Y.Shiro, M.Ota
    • Journal Title

      J.Mol.Biol. 354

      Pages: 801-814

    • Data Source
      KAKENHI-PROJECT-16074217
  • [Journal Article] Structural Characterization of the Proximal and Distal Histidine Environment of Cytoglobin and Neuroglobin2005

    • Author(s)
      H.Sawai, M.Makino, Y.Mizutani, T.Ohta, H.Sugimoto, T.Uno, N.Kawada, K.Yoshizato, T.Kitagawa, Y.Shiro
    • Journal Title

      Biochemistry 44

      Pages: 13257-13265

    • Data Source
      KAKENHI-PROJECT-16074217
  • [Journal Article] Solution Structure of the C-terminal Transcriptional Activator Domain of FixJ from Sinorhizobium meliloti and its Recognition of the fixK Promoter2005

    • Author(s)
      K.Kurashima-Ito, Y.Kasai, K.Hosono, K.Tamura, S.Oue, Y.Ito, H.Nakamura, Y.Shiro
    • Journal Title

      Biochemistry 44

      Pages: 14835-14844

    • Data Source
      KAKENHI-PROJECT-16074217
  • [Journal Article] ADP Reduces the Oxygen Binding Affinity of A Sensory Histidine Kinase, FixL : Possibility of the Enhanced Reciprocating Kinase Reaction2004

    • Author(s)
      H.Nakamura, H.Kumita, K.Imai, T.Iizuka, Y.Shiro
    • Journal Title

      Proc.Natl.Acad.Sci.USA 101

      Pages: 2742-2746

    • Data Source
      KAKENHI-PROJECT-14580616
  • [Journal Article] Structural Basis of Human Cytoglobin for Ligand Binding2004

    • Author(s)
      H.Sugimoto, M.Makino, H.Sawai, N.Kawada, K.Yoshizato, Y.Shiro
    • Journal Title

      J.Mol.Biol. 339

      Pages: 873-885

    • Data Source
      KAKENHI-PROJECT-16074217
  • [Journal Article] Structural Basis of Human Cytoglobin for Ligand Binding2004

    • Author(s)
      H.Sugimoto, M.Makino, H.Sawai, N.Kawada, K.Yoshizato, Y.Shiro
    • Journal Title

      J.Mol.Biol. 339

      Pages: 873-885

    • Data Source
      KAKENHI-PROJECT-14580616
  • [Journal Article] Peroxide Utilizing Biocatalysts : Structural and Functional Diversity of Heme-Containing Enzymes2004

    • Author(s)
      I.Matsunaga, Y.Shiro
    • Journal Title

      Current Opinion Chem.Biol. 8

      Pages: 127-132

    • Data Source
      KAKENHI-PROJECT-16074217
  • [Journal Article] Peroxide Utilizing Biocatalysts : Structural and Functional Diversity of Heme-Containing Enzymes2004

    • Author(s)
      I.Matsunaga, Y.Shiro
    • Journal Title

      Current Opinion Chem.Biol. 8

      Pages: 127-132

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14580616
  • [Journal Article] Design and Synthesis of de Novo Cytochrome c2004

    • Author(s)
      M.Ishida, N.Domae, Y.Shiro, T.Oku, T.Iizuka, Y.Isogai
    • Journal Title

      Biochemistry 43

      Pages: 9823-9833

    • Data Source
      KAKENHI-PROJECT-14580616
  • [Journal Article] LDP Reduces the Oxygen Binding Affinity of A Sensory Histidine Kinase, FixL : Possibility of the Enhanced Reciprocating Kinase Reaction2004

    • Author(s)
      H.Nakamura, H.Kumita, K.Imai, T.Iizuka, Y.Shiro
    • Journal Title

      Proc.Natl.Acad.Sci. USA 101

      Pages: 2742-2746

    • Data Source
      KAKENHI-PROJECT-16074217
  • [Journal Article] NO Reduction by Nitric Oxide Reductase from Denitrifying Bacterium Pseudomonas aeruginosa : Characterization of Reaction Intermediates That Appear in the Single-Turnover Cycle2004

    • Author(s)
      H.Kumita, K.Matsuura, T.Hino, S.Takahashi, H.Hori, Y.Fukumori, I.Morishima, Y.Shiro
    • Journal Title

      J.Biol.Chem. 279

      Pages: 55247-55254

    • Data Source
      KAKENHI-PROJECT-14580616
  • [Journal Article] NO Reduction by Nitric Oxide Reductase from Denitrifying Bacterium Pseudomonas aeruginosa : Characterization of Reaction Intermediates That Appear in the Single-Turnover Cycle2004

    • Author(s)
      H.Kumita, K.Matsuura, T.Hino, S.Takahashi, H.Hori, Y.Fukumori, I.Morishima, Y.Shiro
    • Journal Title

      J.Biol.Chem. 279

      Pages: 55247-55254

    • Data Source
      KAKENHI-PROJECT-16074217
  • [Journal Article] Peroxide Utilizing Biocatalysis : Structural and Functional Diversity of Heme-Containing Enzymes2004

    • Author(s)
      I.Matsunaga, Y.Shiro
    • Journal Title

      Current Opinion Chem.Biol. 8

      Pages: 127-132

    • Data Source
      KAKENHI-PROJECT-14580616
  • [Journal Article] NO Reduction by Nitric Oxide Reductase from Denitrifying Bacterium Pseudomonas aeruginosa : Characterization of Reaction Intermediates That Appear in the Single-Turnover Cycle2004

    • Author(s)
      H. Kumita, K. Matsuura, T. Hino, S. Takahashi, H. Hori, Y. Fukumori, I. Morishima, Y. Shiro
    • Journal Title

      J. Biol. Chem. 279

      Pages: 55247-55254

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16074217
  • [Journal Article] NO Reduction by Nitric Oxide Reductase from Denitrifying Bacterium Pseudomonas aeruginosa : Characterization of Reaction Interaediates That Appear in the Single-Turnover Cycle2004

    • Author(s)
      H. Kumita, K. Matsuura, T. Hino, S. Takahashi, H. Hori, Y. Fukumori, I.Morishima, Y. Shiro
    • Journal Title

      J. Biol. Chen. 279

      Pages: 55247-55254

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16074217
  • [Journal Article] ADP reduces the oxygen binding affinity of a sensory histidine kinase FixL : The possibility of an enhanced reciprocating kinase reaction.2004

    • Author(s)
      Hiro Nakamura, Hideyuki Kumita, Kiyohiro Imai, Tetsutaro Iizuka, Yoshitsugu Shiro
    • Journal Title

      Proc.Natl.Acad.Sci. USA 101・9

      Pages: 2742-2746

    • Data Source
      KAKENHI-PROJECT-12147210
  • [Journal Article] D88A Mutant of Cytochrome P450nor Provides Kinetic Evidence for Direct Complex Formation with Electron Donor NADH2004

    • Author(s)
      M.Umemura, F.Su, N.Takaya, Y.Shiro, H.Shoun
    • Journal Title

      Eur.J.Biochem. 271

      Pages: 2887-2894

    • Data Source
      KAKENHI-PROJECT-16074217
  • [Journal Article] Design and Synthesis of de Novo Cytochrome c2004

    • Author(s)
      M.Ishida, N.Domae, Y.Shiro, T.Oku, T.Iizuka, Y.Isogai
    • Journal Title

      Biochemistry 43

      Pages: 9823-9833

    • Data Source
      KAKENHI-PROJECT-16074217
  • [Journal Article] D88A Mutant of Cytochrome P450nor Provides Kinetic Evidence for Direct Complex Formation with Electron Donor NADH2004

    • Author(s)
      M.Umemura, F.Su, N.Takaya, Y.Shiro, H.Shoun
    • Journal Title

      Eur.J.Biochem. 271

      Pages: 2887-2894

    • Data Source
      KAKENHI-PROJECT-14580616
  • [Patent] 蛋白質・気体複合体結晶の作成方法2006

    • Inventor(s)
      永野真吾, 城 宜嗣
    • Industrial Property Rights Holder
      永野真吾, 城 宜嗣
    • Industrial Property Number
      2006-208427
    • Filing Date
      2006-07-31
    • Data Source
      KAKENHI-PROJECT-18054034
  • [Presentation] Elucidation of Mechanisms for Catalytic Reaction of Nitric Oxide Reductases by Time-resolved Techniques2022

    • Author(s)
      T. Tosha, H. Takeda, Y. Shiro and M. Kubo
    • Organizer
      International Conference on Porphyrins and Phthalocyanines (ICPP-12)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H00926
  • [Presentation] Elucidation of Mechanisms for Catalytic Reaction of Nitric Oxide Reductases by Time-resolved Techniques2022

    • Author(s)
      T. Tosha, H. Takeda, Y. Shiro and M. Kubo
    • Organizer
      International Conference on Porphyrins and Phthalocyanines (ICPP-12)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Presentation] Molecular Mechanism of NO Reduction Catalyzed by Fe-containing Nitric Oxide Reductases2022

    • Author(s)
      Y. Shiro
    • Organizer
      8th Asian Conference on Coordination Chemistry (ACCC8)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Presentation] 鉄の生体内動態の分子科学2022

    • Author(s)
      城 宜嗣
    • Organizer
      第2回レドックスR&D戦略委員会 春のシンポジウム 最先端技術が切り拓くレドックスバイオロジー
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H00926
  • [Presentation] 鉄の生体内動態の分子科学2022

    • Author(s)
      城 宜嗣
    • Organizer
      第2回レドックスR&D戦略委員会 春のシンポジウム 最先端技術が切り拓くレドックスバイオロジー
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Presentation] Molecular Mechanism of NO Reduction Catalyzed by Fe-containing Nitric Oxide Reductases2022

    • Author(s)
      Y. Shiro
    • Organizer
      8th Asian Conference on Coordination Chemistry (ACCC8)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H00926
  • [Presentation] Time-resolved Techniques Provide Mechanism for Nitric Oxide Reduction by Nitric Oxide Reductase2021

    • Author(s)
      T. Tosha, H. Takeda, Y. Shiro and M. Kubo
    • Organizer
      The International Chemical Congress of Pacific Basin Societies 2021 (Pacifichem 2021)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H00926
  • [Presentation] ヘムABCトランスポーターの基質輸送機構に関する分光学的解析2021

    • Author(s)
      木村哲就, 浅田拓也, 仲絢香, 林沙英, 城宜嗣, 杉本宏
    • Organizer
      第47回生体分子科学討論会
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Presentation] ナノディスク再構成型BhuUV-Tによる段階的な基質輸送の分光学的観察2021

    • Author(s)
      木村哲就, 浅田拓也, 林沙英, 鍔木基成, 城宜嗣, 杉本宏
    • Organizer
      第21回蛋白質科学会年会
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Presentation] 酸素バリア性フィルムを用いた嫌気条件下での一酸化窒素還元酵素反応中間体の構造解析への挑戦2021

    • Author(s)
      榛葉幹治、松浦滉明、平田邦生、山本雅貴、城宜嗣、當舎武彦
    • Organizer
      第47回生体分子科学討論会
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Presentation] 分子構造を基盤にした鉄結合タンパク質の機能解明:生命金属科学への展開をめざして2021

    • Author(s)
      城 宜嗣
    • Organizer
      第15回バイオ関連化学シンポジウム
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Presentation] ヒト腸管細胞モデル系を用いた鉄イオンの吸収を向上させる食品成分の探索とそれらの成分が鉄輸送関連タンパク質に作用する分子機構2021

    • Author(s)
      髙原教代、杉本宏、神戸大朋、城宜嗣、澤井仁美
    • Organizer
      第94回日本生化学会大会
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Presentation] 分子構造を基盤にした鉄結合タンパク質の機能解明:Functional Studies of Iron-Related Proteins on Molecular Basis2021

    • Author(s)
      城 宜嗣
    • Organizer
      日本化学会第101春季年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H00926
  • [Presentation] 分子構造を基盤にした鉄結合タンパク質の機能解明 生命金属科学への展開をめざして2021

    • Author(s)
      城 宜嗣
    • Organizer
      第15回バイオ関連化学シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H00926
  • [Presentation] Structural Analyses of ABC Transporters in Nucleotide Bound States Investigated by CW-ESR Spectroscopy2021

    • Author(s)
      仲絢香、小堀康博、鍔木基成、城宜嗣、杉本宏、木村哲就
    • Organizer
      第59回日本生物物理学会年会
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Presentation] 分子構造を基盤にした鉄結合タンパク質の機能解明:Functional Studies of Iron-Related Proteins on Molecular Basis2021

    • Author(s)
      城 宜嗣
    • Organizer
      日本化学会第101春季年会
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Presentation] 『生命金属科学』のめざすところ2020

    • Author(s)
      城 宜嗣
    • Organizer
      CSJ化学フェスタ
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Presentation] 『生命金属科学』のめざすところ2020

    • Author(s)
      城 宜嗣
    • Organizer
      CSJ化学フェスタ
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H00926
  • [Presentation] 分子構造を基盤にしたヘムタンパク質の機能解明~生命金属科学への展開をめざして~2019

    • Author(s)
      城 宜嗣
    • Organizer
      錯体化学会第69回討論会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H00926
  • [Presentation] Dynamics of Nitric Oxide in Cellular Systems: NO Generation and Decomposition2019

    • Author(s)
      Shiro Y.
    • Organizer
      KTJ Bioinorganic Chemistry Symposium 2019 (KTJ-BICS 2019)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Presentation] ヘム蛋白質の機能を司る構造・ダイナミクスとエネルギー流:実験と理論2019

    • Author(s)
      城 宜嗣
    • Organizer
      第57回日本生物物理学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H00926
  • [Presentation] Dynamics of Nitric Oxide in Bacterial Cellular Systems: NO Generation and Decomposition2019

    • Author(s)
      Shiro, Y.
    • Organizer
      Japan-BIOCEV Symposium: Macromolecules; Structure, Function and Beyond
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Presentation] Dynamics of Nitric Oxide in Bacterial Cellular Systems: NO Generation and Decomposition2019

    • Author(s)
      Shiro, Y.
    • Organizer
      Japan-BIOCEV Symposium: Macromolecules; Structure, Function and Beyond
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H00926
  • [Presentation] 分子構造を基盤にしたヘムタンパク質の機能解明~生命金属科学への展開をめざして~2019

    • Author(s)
      城 宜嗣
    • Organizer
      錯体化学会第69回討論会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Presentation] ヘム蛋白質の機能を司る構造・ダイナミクスとエネルギー流:実験と理論2019

    • Author(s)
      城 宜嗣
    • Organizer
      第57回日本生物物理学会年会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Presentation] Dynamics of Nitric Oxide in Cellular Systems: NO Generation and Decomposition2019

    • Author(s)
      Shiro Y.
    • Organizer
      KTJ Bioinorganic Chemistry Symposium 2019 (KTJ-BICS 2019)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H00926
  • [Presentation] Coordination and Electronic Structures of Short-Lived Intermediate of Heme-Containing NO Reductases2018

    • Author(s)
      Shiro, Y.
    • Organizer
      233rd ECS Meeting, Seattle, USA
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Presentation] Characterization of Sort-Lived Reaction Intermediates of Nitric Oxide Reductases by Time-Resolved Techniques2018

    • Author(s)
      Takeda, H., Nomura T., Tosha, T., Sugimoto, H., Kubo, M., Shiro, Y.
    • Organizer
      9th Asian Biological Inorganic Chemistry (AsBIC-9), Natl. Univ. Singapore
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Presentation] Characterization of Coordination and Electronic Structures of Intermediates Appeared in NO Reduction by NO Reductases2018

    • Author(s)
      Shiro, Y.
    • Organizer
      5th Ringberg Workshop on Structural Biology with FELs
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Presentation] Coordination and Electronic Structures of Short-Lived Intermediate in Heme-Containing NO Reductases2018

    • Author(s)
      Shiro, Y.
    • Organizer
      Chemistry and Biology of Tetrapyrroles” Gordon Research Conference, Newport, USA
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Presentation] 時間分解可視・赤外吸収分光法を用いた一酸化窒素還元酵素のNO還元反応機構の解明2017

    • Author(s)
      武田英恵, 木村哲就, 野村高志, 松林明子, 石井頌子, 當舎武彦, 城宜嗣, 久保稔
    • Organizer
      日本生物物理学会第54回年会
    • Data Source
      KAKENHI-PROJECT-15H05476
  • [Presentation] Structural Basis for Molecular Mechanism of Bacterial Nitric Oxide Reductases2017

    • Author(s)
      Shiro, Y.
    • Organizer
      IGER Intl. Symp. Physics of Life
    • Place of Presentation
      名大、ES Hall、名古屋
    • Year and Date
      2017-03-25
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Presentation] 時間分解可視吸収分光測定によるヘム ABC トランスポーターの輸送メカニズム解析2017

    • Author(s)
      林沙英, 城宜嗣, 杉本宏, 木村哲就
    • Organizer
      第17回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-15H05476
  • [Presentation] ABCトランスポーターの分子機構解明を目指した時間分解測定法の開発2017

    • Author(s)
      木村哲就、林沙英、大西萌、杉本宏、城宜嗣、小堀康弘、池本夕佳
    • Organizer
      第43回生体分子科学討論会
    • Place of Presentation
      カレッジプラザ & IYATAKA(秋田市)
    • Year and Date
      2017-06-23
    • Data Source
      KAKENHI-PROJECT-15H05476
  • [Presentation] 可視吸収分光測定によるヘムABCトランスポーター; BhuUVの輸送メカニズム解析2017

    • Author(s)
      林沙英, 城宜嗣, 杉本宏, 木村哲就
    • Organizer
      第44回体分子科学討論会
    • Data Source
      KAKENHI-PROJECT-15H05476
  • [Presentation] 時間分解可視吸収分光測定によるヘムABCトランスポーターの輸送メカニズム解析2017

    • Author(s)
      林沙英、城宜嗣、杉本宏、木村哲就
    • Organizer
      第17回日本蛋白質科学会年会
    • Place of Presentation
      仙台国際センター(仙台市)
    • Year and Date
      2017-06-20
    • Data Source
      KAKENHI-PROJECT-15H05476
  • [Presentation] 可視吸収分光測定によるヘムABCトランスポーター; BhuUVの輸送メカニズム解析2017

    • Author(s)
      林沙英, 城宜嗣, 杉本宏, 木村哲就
    • Organizer
      2017年度生命科学系学会合同年次大会
    • Data Source
      KAKENHI-PROJECT-15H05476
  • [Presentation] マイクロ流路ミキサーを用いた時間分解分光測定による ABC トランスポーターの分子機構解析2017

    • Author(s)
      木村哲就, 林沙英, 大西萌, 城宜嗣, 杉本宏, 池本夕佳
    • Organizer
      第17回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-15H05476
  • [Presentation] マイクロ流路ミキサーを用いた時間分解分光測定によるABCトランスポーターの輸送機構解析2017

    • Author(s)
      木村哲就、林沙英、大西萌、杉本宏、城宜嗣、小堀康弘、池本夕佳
    • Organizer
      第17回日本蛋白質科学会年会
    • Place of Presentation
      仙台国際センター(仙台市)
    • Year and Date
      2017-06-20
    • Data Source
      KAKENHI-PROJECT-15H05476
  • [Presentation] ABCトランスポーターの分子機構解明を目指した時間分解測定法の開発2017

    • Author(s)
      木村哲就, 林沙英, 大西萌, 城宜嗣, 杉本宏, 小堀康弘, 池本夕佳
    • Organizer
      第44回生体分子科学討論会
    • Data Source
      KAKENHI-PROJECT-15H05476
  • [Presentation] Structural Basis for Molecular Mechanism of Bacterial Nitric Oxide Reductases2017

    • Author(s)
      Shiro, Y.
    • Organizer
      IGER Intl. Symp. Physics of Life
    • Place of Presentation
      名大、ES Hall、名古屋
    • Year and Date
      2017-03-25
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26620140
  • [Presentation] NO Dynamics in Biology: Its Generation and Decomposition2016

    • Author(s)
      Shiro, Y.
    • Organizer
      Royal Society Meeting Inorganic Chemistry
    • Place of Presentation
      阪大、銀杏会館、豊中
    • Year and Date
      2016-10-26
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26620140
  • [Presentation] Structural dynamics in the enzymatic reaction of membrane protein; nitric oxide reductase, revealed by the novel time-resolved spectroscopic measurements.2016

    • Author(s)
      T. Kimura, H. Takeda, S. Ishii, T. Tosha, Y. Shiro, M. Kubo
    • Organizer
      42nd Naito Conference "In the Vanguard of Structural Biology: Revolutionizing Life Sciences"
    • Place of Presentation
      シャトレーゼ ガトーキングダム サッポロ(北海道札幌市)
    • Year and Date
      2016-10-04
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05476
  • [Presentation] Molecular Mechanism of NO Reduction by Bacterial Nitric Oxide Reductases2016

    • Author(s)
      Shiro, Y.
    • Organizer
      ICCP9
    • Place of Presentation
      Nanjing, China
    • Year and Date
      2016-06-03
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26620140
  • [Presentation] Intermediate structures of the catalytic site in membrane proteins revealed by time-resolved spectroscopy with micro-channel devices.2016

    • Author(s)
      T. Kimura, H. Takeda, S. Ishii, T. Tosha, Y. Shiro, M. Kubo
    • Organizer
      第54回日本生物物理学会年会
    • Place of Presentation
      つくば国際会議場(つくば市)
    • Year and Date
      2016-11-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05476
  • [Presentation] NO reduction mechanism in the binuclear catalytic center of nitric oxide reductase revealed by novel micro-channel flow-flash spectrometers.2016

    • Author(s)
      T. Kimura, H. Takeda, S. Ishii, T. Tosha, Y. Shiro, M. Kubo
    • Organizer
      Gordon Research Conference "Metallocofactors"
    • Place of Presentation
      Stonehill College (Easton, MA, USA)
    • Year and Date
      2016-06-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05476
  • [Presentation] NO Dynamics in Biology: Its Generation and Decomposition2016

    • Author(s)
      Shiro, Y.
    • Organizer
      Royal Society Meeting Inorganic Chemistry
    • Place of Presentation
      阪大、銀杏会館、豊中
    • Year and Date
      2016-10-26
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Presentation] Molecular mechanism of the catalytic reaction of NO reductase revealed by novel time-resolved visible/IR absorption spectrometers with microfluidic device2016

    • Author(s)
      Tetsunari Kimura, Hanae Takeda, Shoko Ishii, Takehiko Tosha, Yoshitsugu Shiro, Minoru Kubo
    • Organizer
      Biophysical Society 60th Annual Meeting
    • Place of Presentation
      Los Angeles, CA, USA
    • Year and Date
      2016-02-27
    • Data Source
      KAKENHI-PROJECT-15H05476
  • [Presentation] Molecular Mechanism of NO Reduction by Bacterial Nitric Oxide Reductases2016

    • Author(s)
      Shiro, Y.
    • Organizer
      229th ECS Meeting
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2016-05-29
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Presentation] マイクロ流路フロー・フラッシュ時間分解赤外分光法による一酸化窒素還元酵素の反応機構解析2016

    • Author(s)
      木村哲就、武田英恵、石井頌子、當舎武彦、城宜嗣、久保稔
    • Organizer
      第43回生体分子科学討論会
    • Place of Presentation
      名古屋大学(名古屋市)
    • Year and Date
      2016-06-24
    • Data Source
      KAKENHI-PROJECT-15H05476
  • [Presentation] Damage-free X-ray Crystallographic Analysis of P450nor in the NO Bound Form using SACLA.2016

    • Author(s)
      Kubo, M., Nomura, T., Nishida, T., Tosha, T., Sugimoto, H., Kimura, T., Takano, Y., Yamashita, K., Hirata, K., Ueno, G., Ago, H., Yamamoto, M., Shiro, Y.
    • Organizer
      British Biophysical Society 2016 Biennial Meeting
    • Place of Presentation
      Liverpool, UK
    • Year and Date
      2016-07-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-26620140
  • [Presentation] Molecular Mechanism of NO Reduction by Bacterial Nitric Oxide Reductases2016

    • Author(s)
      Shiro, Y.
    • Organizer
      229th ECS Meeting
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2016-05-29
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26620140
  • [Presentation] Molecular Mechanism of NO Reduction by Bacterial Nitric Oxide Reductases2016

    • Author(s)
      Shiro, Y.
    • Organizer
      ICCP9
    • Place of Presentation
      Nanjing, China
    • Year and Date
      2016-06-03
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Presentation] Damage-free X-ray Crystallographic Analysis of P450nor in the NO Bound Form using SACLA.2016

    • Author(s)
      Kubo, M., Nomura, T., Nishida, T., Tosha, T., Sugimoto, H., Kimura, T., Takano, Y., Yamashita, K., Hirata, K., Ueno, G., Ago, H., Yamamoto, M., Shiro, Y.
    • Organizer
      British Biophysical Society 2016 Biennial Meeting
    • Place of Presentation
      Liverpool, UK
    • Year and Date
      2016-07-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Presentation] Development of a time-resolved visible/IR absorption spectrometer with a novel microfluidic device and its application to catalytic reaction of NO reductase2015

    • Author(s)
      Tetsunari Kimura, Shoko Ishii, Takehiko Tosha, Yoshitsugu Shiro, Minoru Kubo
    • Organizer
      PacifiChem 2015
    • Place of Presentation
      Honolulu, HI, USA
    • Year and Date
      2015-12-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05476
  • [Presentation] マイクロ流路を用いたフローフラッシュ赤外吸収分光法の開発と一酸化窒素還元酵素の反応中間体解析への応用2015

    • Author(s)
      木村哲就, 石井頌子, 當舎武彦, 城宜嗣, 久保稔
    • Organizer
      日本生物物理学会第52回年会
    • Place of Presentation
      金沢大学(石川県・金沢市)
    • Year and Date
      2015-09-13
    • Data Source
      KAKENHI-PROJECT-15H05476
  • [Presentation] Molecular Mechanism of NO Reduction by Bacterial Nitric Oxide Reductases”2015

    • Author(s)
      Y. Shiro
    • Organizer
      PACIFICHEM2015 The International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Honolulu, USA
    • Year and Date
      2015-12-15
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Presentation] Molecular Mechanism of NO Decomposition by Nitric Oxide Reductases2015

    • Author(s)
      Y. Shiro
    • Organizer
      ICBIC17 17th International Conference of Biological Inorganic Chemistry
    • Place of Presentation
      Beijing, China
    • Year and Date
      2015-07-20
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26620140
  • [Presentation] Proton Transfer in Bacterial Nitric Oxide Reductases Coupled with NO Reduction2015

    • Author(s)
      Y. Shiro
    • Organizer
      PACIFICHEM2015 The International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Honolulu, USA
    • Year and Date
      2015-12-15
    • Data Source
      KAKENHI-PROJECT-26620140
  • [Presentation] Dynamics of Nitric Oxide in Bacterial Cellular System2015

    • Author(s)
      Y. Shiro
    • Organizer
      “Cell Biology of Metals” Gordon Research Conference
    • Place of Presentation
      West Dover, VT, USA
    • Year and Date
      2015-07-26
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26620140
  • [Presentation] Molecular Mechanism of NO Reduction by Bacterial Nitric Oxide Reductases2015

    • Author(s)
      Y. Shiro
    • Organizer
      PACIFICHEM2015 The International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Honolulu, USA
    • Year and Date
      2015-12-15
    • Data Source
      KAKENHI-PROJECT-26620140
  • [Presentation] マイクロ流体フロー・フラッシュ赤外分光測定系による一酸化窒素還元酵素の触媒反応の実時間観察2015

    • Author(s)
      木村哲就, 石井頌子, 當舎武彦, 城宜嗣, 久保稔
    • Organizer
      第9回分子科学討論会
    • Place of Presentation
      東京工業大学(東京都・目黒区)
    • Year and Date
      2015-09-16
    • Data Source
      KAKENHI-PROJECT-15H05476
  • [Presentation] Proton Transfer in Bacterial Nitric Oxide Reductases Coupled with NO Reduction2015

    • Author(s)
      Y. Shiro
    • Organizer
      PACIFICHEM2015 The International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Honolulu, USA
    • Year and Date
      2015-12-15
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Presentation] Dynamics of Nitric Oxide in Bacterial Cellular System2015

    • Author(s)
      Y. Shiro
    • Organizer
      “Cell Biology of Metals” Gordon Research Conference
    • Place of Presentation
      West Dover, VT, USA
    • Year and Date
      2015-07-26
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Presentation] Molecular Mechanism of NO Decomposition by Nitric Oxide Reductases2015

    • Author(s)
      Y. Shiro
    • Organizer
      ICBIC17 17th International Conference of Biological Inorganic Chemistry
    • Place of Presentation
      Beijin, China
    • Year and Date
      2015-07-20
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Presentation] Biometal Science in RIKEN2013

    • Author(s)
      Yoshitsugu Shiro
    • Organizer
      RIKEN - University of Liverpool Joint Symposium
    • Place of Presentation
      Liverpool, UK
    • Invited
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Presentation] Functional Characterization of Some Hemoproteins Based in Their Molecular Structures2013

    • Author(s)
      Yoshitsugu Shiro
    • Organizer
      Symposium on “Modern Trends in Inorganic Chemistry”
    • Place of Presentation
      Roorkee, India
    • Invited
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Presentation] Fungal and Bacterial Nitric Oxide Reductases: Structures and Functions2013

    • Author(s)
      Yoshitsugu Shiro
    • Organizer
      18th International Conference on Cytochrome P450; Biochemistry, Biophysics and Structure
    • Place of Presentation
      Seattle, USA
    • Invited
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Presentation] Structural Basis for NO Reduction by Bacterial Nitric Oxide Reductases2012

    • Author(s)
      Shiro, Y.
    • Organizer
      17th European Bioenergetics Conference 2012 (EBEC 2012)
    • Place of Presentation
      Freiburg, Germany
    • Year and Date
      2012-09-15
    • Invited
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Presentation] Functional Characterization of Some Hemoproteins Based on Their Molecular Structures2012

    • Author(s)
      Shiro, Y
    • Organizer
      The First International Symposium on Biofunctional Chemistry (ISBC2012)
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] Structural Basis for NO Reduction by Bacterial Nitric Oxide Reductases2012

    • Author(s)
      Shiro, Y.
    • Organizer
      17th European Bioenergetics Conference 2012 (EBEC 2012)
    • Place of Presentation
      Freiburg, Germany
    • Invited
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] Functional Characterization of Some Hemoproteins Based on Their Molecular Structures2012

    • Author(s)
      Shiro, Y.
    • Organizer
      The 6th Asian Biological Inorganic Chemistry Conference (AsBIC6)
    • Place of Presentation
      Hong Kong
    • Year and Date
      2012-11-05
    • Invited
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Presentation] Functional Characterization of Some Hemoproteins Based on Their Molecular Structures2012

    • Author(s)
      Shiro, Y
    • Organizer
      The 6^<th> Asian Biological Inorganic Chemistry Conference (AsBIC6)
    • Place of Presentation
      Hong Kong, Plenary Lecture
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] Functional Characterization of Some Hemoproteins Based on Their Molecular Structures2012

    • Author(s)
      Shiro, Y.
    • Organizer
      The First International Symposium on Biofunctional Chemistry (ISBC2012)
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2012-11-28
    • Invited
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Presentation] Molecular Structures and Mechanism of Bacterial Nitric Oxide Reductase2012

    • Author(s)
      Shiro, Y
    • Organizer
      Seventh International Conference on Porphyrins and Phtalocyanines
    • Place of Presentation
      Jeju, Korea
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] Functional Characterization of Some Hemoproteins Based on Their Molecular Structures2012

    • Author(s)
      Shiro, Y.
    • Organizer
      The First International Symposium on Biofunctional Chemistry (ISBC2012)
    • Place of Presentation
      Tokyo, Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] Structural Basis for NO Reduction by Bacterial Nitric Oxide Reductases2012

    • Author(s)
      Shiro, Y
    • Organizer
      17^<th> European Bioenergetics Conference 2012 (EBEC 2012)
    • Place of Presentation
      Freiburg, Germany
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] Functional Characterization of Some Hemoproteins Based on Their Molecular Structures2012

    • Author(s)
      Shiro, Y.
    • Organizer
      The 6th Asian Biological Inorganic Chemistry Conference (AsBIC6)
    • Place of Presentation
      Hong Kong
    • Invited
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] Molecular Structures and Mechanism of Bacterial Nitric Oxide Reductase2012

    • Author(s)
      Shiro, Y.
    • Organizer
      Seventh International Conference on Porphyrins and Phtalocyanines
    • Place of Presentation
      Jeju, Korea
    • Year and Date
      2012-07-01
    • Invited
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Presentation] Molecular Structures and Mechanism of Bacterial Nitric Oxide Reductase2011

    • Author(s)
      Shiro, Y.
    • Organizer
      Mini-symposium on "Proton Transport across Biological Membranes" of the Royal Swedish Academy of Sciences
    • Place of Presentation
      Stockholm, Sweden(招待講演)
    • Year and Date
      2011-06-14
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] Molecular Structures and Mechanism of Bacterial Nitric Oxide Reductase2011

    • Author(s)
      Hino, T., Matsumoto, Y., Pisliakov, A., Nagano, S., Sugimoto, H., Sugita, Y., Shiro, Y
    • Organizer
      Third Korea-Japan Seminars on Biomolecular Sciences - Experiments and Simulations
    • Place of Presentation
      Jeju, Korea
    • Year and Date
      2011-02-28
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] Iron in Biology2011

    • Author(s)
      Shiro, Y.
    • Organizer
      RIKEN-University of Liverpool Joint Symposium
    • Place of Presentation
      Liverpool, UK(招待講演)
    • Year and Date
      2011-09-15
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Presentation] Molecular Structures and Mechanism of Bacterial Nitric Oxide Reductase2011

    • Author(s)
      Shiro, Y.
    • Organizer
      15th International Conference of Biological Inorganic Chemistry
    • Place of Presentation
      Vancouver, Canada(招待講演)
    • Year and Date
      2011-08-09
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] Molecular Structures and Mechanism of Bacterial Nitric Oxide Reductase2011

    • Author(s)
      Shiro, Y.
    • Organizer
      15th International Conference of Biological Inorganic Chemistry
    • Place of Presentation
      Vancouver, Canada(招待講演)
    • Year and Date
      2011-08-09
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Presentation] Molecular Structures and Mechanism of Bacterial Nitric Oxide Reductase2011

    • Author(s)
      T.Hino, Y.Matsumoto, Andrei Pisliakov, S.Nagano, H.Sugimoto, Yuji Sugita, Y.Shiro
    • Organizer
      Third Korea-Japan Seminars on Biomolecular Sciences : -Experiments and Simulations
    • Place of Presentation
      Jeju, Korea
    • Year and Date
      2011-02-28
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Presentation] Molecular Structures and Mechanism of Bacterial Nitric Oxide Reductase2011

    • Author(s)
      Shiro, Y
    • Organizer
      15th International Conference of Biological Inorganic Chemistry
    • Place of Presentation
      Vancouver, Canada, Keynote Lecture
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] Structural Basis for Nitrous Oxide Generation by Bacterial Nitric Oxide Reductases2011

    • Author(s)
      Shiro, Y.
    • Organizer
      Royal Society Theo Murphy Meeting
    • Place of Presentation
      Buckinghamshire, UK(招待講演)
    • Year and Date
      2011-05-24
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] Iron in Biology2011

    • Author(s)
      Shiro, Y.
    • Organizer
      RIKEN-University of Liverpool Joint Symposium
    • Place of Presentation
      Liverpool, UK(招待講演)
    • Year and Date
      2011-09-15
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] Molecular Structures and Mechanism of Bacterial Nitric Oxide Reductase2011

    • Author(s)
      Shiro, Y
    • Organizer
      Mini-symposium on "Proton Transport across Biological Membranes" of the Royal Swedish Academy of Sciences
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      2011-06-14
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] Structural Basis for Nitrous Oxide Generation by Bacterial Nitric Oxide Reductases2011

    • Author(s)
      Shiro, Y.
    • Organizer
      Royal Society Theo Murphy Meeting
    • Place of Presentation
      Buckinghamshire, UK(招待講演)
    • Year and Date
      2011-05-24
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Presentation] Molecular Structures and Mechanism of Bacterial Nitric Oxide Reductase2011

    • Author(s)
      Shiro, Y.
    • Organizer
      Mini-symposium on "Proton Transport across Biological Membranes" of the Royal Swedish Academy of Sciences
    • Place of Presentation
      Stockholm, Sweden(招待講演)
    • Year and Date
      2011-06-14
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Presentation] Structural Basis for Nitrous Oxide Generation by Bacterial Nitric Oxide Reductases2011

    • Author(s)
      Shiro, Y
    • Organizer
      Royal Society Theo Murphy Meetin
    • Place of Presentation
      Buckinghamshire, UK
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] Molecular Structures and Mechanism of Bacterial Nitric Oxide Reductase2011

    • Author(s)
      T.Hino, Y.Matsumoto, Andrei Pisliakov, S.Nagano, H.Sugimoto, Yuji Sugita, Y.Shiro
    • Organizer
      Third Korea-Japan Seminars on Biomolecular Sciences : -Exneriments and Simulations
    • Place of Presentation
      Jeju, Korea
    • Year and Date
      2011-02-28
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] Iron in Biology2011

    • Author(s)
      Shiro, Y
    • Organizer
      RIKEN - University of Liverpool Joint Symposium
    • Place of Presentation
      Liverpool, UK
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] ナノデスクを用いた病原菌の生体鉄感知システムの解析2010

    • Author(s)
      伊藤陽子、當舎武彦、中村寛夫、城宜嗣
    • Organizer
      第33回日本分子生物学年会・第83回日本生化学会大会合同大会(BMB2020)
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-09
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] Nitric Oxide Reductase ; Chemistry of N-O Bond Cleavage and N-N Bond Formation2010

    • Author(s)
      Yoshitsugu Shiro, Tomoya Hino, Yushi Matsumoto, Shingo Nagano, Hiroshi Sugimoto, Takehiko Tosha
    • Organizer
      Sixth International Conference on Porphyrins and Phthalocyanines (ICPP-6)
    • Place of Presentation
      Albuquerque, Mew Mexico, USA
    • Year and Date
      2010-07-06
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] Nitric Oxide Reductase ; Chemistry of N-O Bond Cleavage and N-N Bond Formation2010

    • Author(s)
      Yoshitsugu Shiro, Tomoya Hino, Yushi Matsumoto, Shingo Nagano, Hiroshi Sugimoto, Takehiko Tosha
    • Organizer
      Sixth International Conference on Porphyrins and Phthalocyanines (ICPP-6)
    • Place of Presentation
      Albuquerque, Mew Mexico, USA
    • Year and Date
      2010-07-06
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Presentation] Two-component regulatory System : Cellular signal transduction systems sensing exogenous stimuli2010

    • Author(s)
      Yoshitsugu Shiro, Hiro Nakamura, Yoko Ito, Hiroshi Sugimoto
    • Organizer
      Pacifichem 2010
    • Place of Presentation
      Waikiki, Hawaii, USA
    • Year and Date
      2010-12-16
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Presentation] 嫌気呼吸系の一酸化窒素還元酵素の構造と分子進化2010

    • Author(s)
      永野真吾、松本悠史、當舎武彦、日野智也、杉本宏、城宜嗣
    • Organizer
      第10回日本蛋白質化学会
    • Place of Presentation
      札幌
    • Year and Date
      2010-06-17
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] 二成分情報伝達系複合体構造からわかる環境変化感知からリン酸化への生体シグナル変換機構2010

    • Author(s)
      杉本宏、山田斉爾、中村寛夫、城宜嗣
    • Organizer
      日本結晶学会2010年度年会
    • Place of Presentation
      吹田
    • Year and Date
      2010-12-05
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Presentation] Cooperative L-Trp binding to human tryptophan 2,3-dioxygenase revealed by resonance Raman spectroscopy2010

    • Author(s)
      福村栄維子、杉本宏、三角祐子、小倉尚志、城宜嗣
    • Organizer
      第33回日本分子生物学年会・第83回日本生化学会大会合同大会(BMB2020)
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-09
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] Two-component regulatory System : Cellular signal transduction systemssensing exogenous stimuli2010

    • Author(s)
      Yoshitsugu Shiro, Hiro Nakamura, Yoko Ito, Hiroshi Sugimoto
    • Organizer
      Pacifichem 2010
    • Place of Presentation
      Waikiki, Hawaii, USA
    • Year and Date
      2010-12-16
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] ヘム輸送タンパク質の構造解析2010

    • Author(s)
      直江洋一、杉本宏、城宜嗣
    • Organizer
      第10回日本蛋白質化学会
    • Place of Presentation
      札幌
    • Year and Date
      2010-06-17
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] 立体構造と理論計算に基づく蛍光タンパク質の設計2010

    • Author(s)
      菊地晶裕、長谷川淳也、唐澤智司、城宜嗣
    • Organizer
      第10回日本蛋白質化学会
    • Place of Presentation
      札幌
    • Year and Date
      2010-06-18
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] Cooperative L-Trp binding to human tryptophan 2,3-dioxygenase revealed by resonance Raman spectroscopy2010

    • Author(s)
      福村栄維子、杉本宏、三角祐子、小倉尚志、城宜嗣
    • Organizer
      第33回日本分子生物学年会・第83回日本生化学会大会合同大会(BMB2020)
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-09
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Presentation] シトクロムP450(CYP105A1)の立体構造に基づくビタミンD水酸化反応のデザインと応用2010

    • Author(s)
      杉本宏、林恵子、安田佳織、池田進之介、新京楽、鎌倉昌樹、生城真一、城宜嗣、榊利之
    • Organizer
      第10回日本蛋白質化学会
    • Place of Presentation
      札幌
    • Year and Date
      2010-06-17
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] 二成分情報伝達系複合体構造からわかる環境変化感知からリン酸化への生体シグナル変換機構2010

    • Author(s)
      杉本宏、山田斉爾、中村寛夫、城宜嗣
    • Organizer
      日本結晶学会2010年度年会
    • Place of Presentation
      吹田
    • Year and Date
      2010-12-05
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] ナノデスクを用いた病原菌の生体鉄感知システムの解析2010

    • Author(s)
      伊藤陽子、當舍武彦、中村寛夫、城宜嗣
    • Organizer
      第33回日本分子生物学年会・第83回日本生化学会大会合同大会(BMB2020)
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-09
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Presentation] Two-Component Regulatory System: Cellular Signal Transduction Systems Sensing Exogenous Stimuli2010

    • Author(s)
      Shiro, Y., Nakamura, H., Ito, Y., Sugimoto, H
    • Organizer
      2010 International Chemical Congress of Paci.c Basin Societies
    • Place of Presentation
      Honolulu, USA
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] Nitric Oxide Reductases: Chemistry of N-O bond Cleavage and N-N Bond Formation2010

    • Author(s)
      Shiro, Y., Hino, T., Matsumoto, Y., Nagano, S., Sugimoto, H., Tosha, T
    • Organizer
      Sixth International Conference on Porphyrins and Phtalocyanines
    • Place of Presentation
      New Mexico, USA
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] Cooperative L-Trp Binding to Human Tryptophan 2,3-Dioxygenase Revealed by Resonance Raman Spectroscopy2009

    • Author(s)
      E.Fukumura, H.Sugimoto, Y.Misumi, T.Ogura, Y.Shiro
    • Organizer
      14th International Conference of Biological Inorganic Chemistry
    • Place of Presentation
      Nagoya, Japan
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Presentation] 共鳴ラマン分光法によるトリプトファン2,3ジオキシゲナーゼの反応機構解析2009

    • Author(s)
      福村栄維子、三角裕子、杉本宏、永野真吾、瀧尾こう二、井柳尭、小倉尚志、城宜嗣
    • Organizer
      第46回生物物理学会
    • Place of Presentation
      徳島、日本
    • Year and Date
      2009-12-03
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Presentation] 分子構造を基盤にしたP450の生理機能の理解2009

    • Author(s)
      城宜嗣
    • Organizer
      第82回日本生化学会
    • Place of Presentation
      神戸、日本
    • Year and Date
      2009-10-21
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Presentation] Structure and Function of Nitric Oxide Reductases; Chemistry of NO Reduction and N_2O formation2009

    • Author(s)
      Shiro, Y
    • Organizer
      1st Korea-Japan Seminars on Biomolecular Sciences - Experiments and Simulations
    • Place of Presentation
      Seoul, Korea
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] ガスクロマトグラフィーを用いた膜結合型一酸化窒素還元酵素の活性測定2009

    • Author(s)
      本多佑輔、永野真吾、城宜嗣
    • Organizer
      第82回日本生化学会
    • Place of Presentation
      神戸、日本
    • Year and Date
      2009-10-22
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Presentation] Role of the amino acid residues in the active site of human indoleamine 2,3-dioxygenase2009

    • Author(s)
      Horitani M., Kometani E., Sugimoto H., Shiro Y.
    • Organizer
      14th International Conference on Biological Inorganic Chemistry (ICBIC 14)
    • Place of Presentation
      Nagoya, Japan
    • Year and Date
      2009-07-26
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] Structure and Mechanism of Enzymes Involved in Indolocarbazole Biosynthesis2009

    • Author(s)
      S.Nagano, H.Onaka, S.Shaik, Y.Shiro
    • Organizer
      14th International Conference of Biological Inorganic Chemistry
    • Place of Presentation
      Nagoya, Japan
    • Year and Date
      2009-07-29
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Presentation] DFT and ONION Studies on a Missing Piece in Our Understanding of Heme Chemistry : Bacterial Tryptophan 2, 3-Dioxygenase(TDO)2009

    • Author(s)
      L.W.Chung, X.Li, H.Sugimoto, Y.Shiro, K.Morokuma
    • Organizer
      14th International Conference of Biological Inorganic Chemistry
    • Place of Presentation
      Nagoya, Japan
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Presentation] Detection of the Iron-Oxygen Stretching Raman Mode for Human Indoleamine 2, 3 Dioxygenase in the Oxygenated Form2009

    • Author(s)
      S.Yanagishita, K.Yotsuya, M.Horitani, H.Sugimoto, Y.Shiro, Y.Hashiwaki, T.Ogura
    • Organizer
      14th International Conference of Biological Inorganic Chemistry
    • Place of Presentation
      Nagoya, Japan
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Presentation] Structure and Function of Nitric Oxide Reductases; Chemistry of NO Reduction and N_2O Formation2009

    • Author(s)
      Shiro, Y
    • Organizer
      14th International Conference of Biological Inorganic Chemistry
    • Place of Presentation
      Nagoya, Japan
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] μSR法による鉄ポルフィリンの微視的観測-μSR法によるヘムタンパク質の解明を目指して2009

    • Author(s)
      菊地晶裕、渡邊功雄、城宜嗣
    • Organizer
      第59回錯体化学討論会
    • Place of Presentation
      長崎
    • Year and Date
      2009-09-26
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] 電子供与体キノールから一酸化窒素還元酵素への電子伝達2009

    • Author(s)
      當舎武彦、松本悠史、永野真吾、城宜嗣
    • Organizer
      第82回日本生化学大会
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-24
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] 膜貫通型一酸化窒素還元酵素の結晶構造2009

    • Author(s)
      松本悠史、杉本宏、日野智哉、永野真吾、城宜嗣
    • Organizer
      第46回生物物理学会
    • Place of Presentation
      徳島、日本
    • Year and Date
      2009-12-03
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Presentation] Structure and Function of Nitric Oxide Reductases ; Chemistry of NO Reduction and N_2O formation2009

    • Author(s)
      Yoshitsugu Shiro
    • Organizer
      14th International Conference of Biological Inorganic Chemistry
    • Place of Presentation
      Nagoya, Japan
    • Year and Date
      2009-07-27
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Presentation] Structure and mechanism of enzymes involved in indolocarbazole biosynthesis2009

    • Author(s)
      Nagano S., Onaka H., Shaik S., Shiro Y.
    • Organizer
      14th International Conference on Biological Inorganic Chemistry (ICBIC 14)
    • Place of Presentation
      Nagoya, Japan
    • Year and Date
      2009-07-26
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] Role of the Amino Acid Residues in the Active Site of Human Indoleamine 2, 3-Dioxygenase2009

    • Author(s)
      M.Horitani, E.Kometani, H.Sugimoto, Y.Shiro
    • Organizer
      14th International Conference of Biological Inorganic Chemistry
    • Place of Presentation
      Nagoya, Japan
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Presentation] Cooperative L-Trp binding to human tryptophan 2,3-dioxgenase revealed by Resonance Raman Spectroscopy2009

    • Author(s)
      Fukumura E., Sugimoto H., Misumi Y., Ogura T., Shiro Y.
    • Organizer
      14th International Conference on Biological Inorganic Chemistry (ICBIC 14)
    • Place of Presentation
      Nagoya, Japan
    • Year and Date
      2009-07-26
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] Structure and function of nitric oxide reductases ; chemistry of NO reduction and N_2O formation2009

    • Author(s)
      Yoshitsugu Shiro
    • Organizer
      14th International Conference on Biological Inorganic Chemistry (ICBIC 14)
    • Place of Presentation
      Nagoya, Japan
    • Year and Date
      2009-07-27
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] 電子供与体キノールから一酸化窒素還元酵素への電子伝達2009

    • Author(s)
      當舎武彦、松本悠史、永野真吾、城宜嗣
    • Organizer
      第82回日本生化学会
    • Place of Presentation
      神戸、日本
    • Year and Date
      2009-10-22
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Presentation] 抗生物質ビオラセインの骨格を構築する鍵酵素VioEの構造とメカニズム2009

    • Author(s)
      永野真吾、平野聡、尾仲宏康、浅水俊平、城宜嗣
    • Organizer
      第36回生体分子科学討論会
    • Place of Presentation
      札幌
    • Year and Date
      2009-06-19
    • Data Source
      KAKENHI-PROJECT-21245041
  • [Presentation] 脂質ナノデイスクに再構成したジフテリア菌ChrSのヘム結合とリン酸基転移2009

    • Author(s)
      伊藤陽子、中村寛夫、城宜嗣
    • Organizer
      第82回日本生化学会
    • Place of Presentation
      神戸、日本
    • Year and Date
      2009-10-22
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Presentation] Structure and function of nitric oxide reductases ; chemistry of NO reduction and N2O formation2009

    • Author(s)
      Shiro, Y.
    • Organizer
      14th International Conference on Biological Inorganic Chemistry(ICBIC 14)
    • Place of Presentation
      Nagoya, Japan
    • Data Source
      KAKENHI-PROJECT-17GS0221
  • [Presentation] 膜貫通型一酸化窒素還元酵素の結晶構造2008

    • Author(s)
      松本 悠史, 杉本 宏, 日野 智也, 永野 真吾, 城 宜嗣
    • Organizer
      第46回日本生物物理学会年会
    • Place of Presentation
      福岡, 日本
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Presentation] 二成分情報伝達系複合体の結晶構造解析2008

    • Author(s)
      城 宜嗣
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会(BMB2008)
    • Place of Presentation
      神戸, 日本
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Presentation] Crystal structure and mechanism of cytochrome P450 StaP That constructs the indolocarbazole core2008

    • Author(s)
      Nagano S., Makino M., Asamizu S., Onaka H., Sason S., and Shiro Y.
    • Organizer
      21th Congress and General Assembly of the International Union of Crystallography(IUCr2008)
    • Place of Presentation
      Osaka, Japan
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Presentation] 呼吸酵素の分子進化 : 一酸化窒素から酸素へ2008

    • Author(s)
      城 宜嗣
    • Organizer
      分子研研究会「配位子場制御に基づく機能性錯体の創成と応用〜成体から触媒およびデバイスまで〜」
    • Place of Presentation
      岡崎, 日本
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Presentation] Fungal and bacterial nitric oxide reductases : their structures and reaction mechanisms2008

    • Author(s)
      Shiro Y., Nagano S., and Matsumoto Y
    • Organizer
      5th International Conference on Porphyrins and Phthalocyanines(ICPP-5)
    • Place of Presentation
      Moscow, Russia
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Presentation] Crystal structure of cytochrome P450 105Al in complex with 1α, 2-dihydroxyvitamin D_32008

    • Author(s)
      Sugimoto H., Shinkyo R., Hayashi K., Yoneda S., Yamada M., Kamakura M., Ikushiro S., Shiro Y., and Sakaki T.
    • Organizer
      21th Congress and General Assembly of the International Union of Crystallography(IUCr2008)
    • Place of Presentation
      Osaka, Japan
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Presentation] Fungal and bacterial nitric oxide reductases : Their structures and reaction mechanisms2008

    • Author(s)
      Matsumoto Y., Nagano S., and Shiro Y.
    • Organizer
      The 4th Asian Biological Inorganic Chemistry Conference
    • Place of Presentation
      Jeju, Korea
    • Year and Date
      2008-11-11
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Presentation] インドロカルバゾール系天然物の骨格構造を構築する酵素の構造と機能2008

    • Author(s)
      浅野 真吾, 牧野 正知, 平野 聡, 浅水 俊平, 尾仲 宏康, 城 宜嗣,
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会(BMB2008)
    • Place of Presentation
      神戸, 日本
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Presentation] インドロカルパゾール系生理活性物質の分子骨格を構築するシトクロムP450 StaP の構造と反応メカニズム2008

    • Author(s)
      永野 真吾, 尾仲 宏康, 浅水 俊平, 牧野 正知, 城 宜嗣,
    • Organizer
      第58回錯体化学討論会
    • Place of Presentation
      金沢, 日本
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Presentation] Separetion of phosphoprotein isotypes with the same pohsphate stoichiometry phosphate-affinity SDS-PAGE2008

    • Author(s)
      木下 英司, 木下 恵美子, 松原 守, 山田 斉爾, 中村 寛夫, 城 宜嗣, 青木 悠里, 沖田 鋼季
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会(BMB2008)
    • Place of Presentation
      神戸, 日本
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Presentation] Structure of cytochrome P450 105A1 in complex with 1α, 25-dihydroxyvitamin D_32008

    • Author(s)
      Sugimoto H., Shinkyo R., Hayashi K., Yoneda S., Yamasa M., Kamakura M., Ikushiro S., Shiro Y., and Sakaki T.
    • Organizer
      9th International Symposium on Cytochrome P450 Biodiversity and Biotechnology
    • Place of Presentation
      Nice France
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Presentation] 共鳴ラマン分光法によるトリプトファン2, 3-ジオキシゲナーゼの反応機構解析2008

    • Author(s)
      福村 栄維子, 三角 裕子, 杉本 宏, 永野 真吾, 瀧尾 擴士, 井柳 堯, 小倉 尚志, 城 宜嗣,
    • Organizer
      第46回日本生物物理学会年会
    • Place of Presentation
      福岡, 日本
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Presentation] 呼吸酵素の分子進化 : 一酸化窒素から酸素へ2008

    • Author(s)
      松本 悠史, 永野 真吾, 城 宜嗣
    • Organizer
      第8回日本蛋白質科学会年会
    • Place of Presentation
      船堀, 日本
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Presentation] シトクロムP450 105A1 の結晶構造とビタミンD_3活性化反応の分子メカニズム2008

    • Author(s)
      杉本 宏, 新京 楽, 林 恵子, 米田 幸世, 山田 雅人, 鎌倉 昌樹, 生城 真一, 城 宜嗣, 榊 利之,
    • Organizer
      第58回錯体化学討論会
    • Place of Presentation
      金沢, 日本
    • Data Source
      KAKENHI-PROJECT-20050033
  • [Presentation] Intra-and Intermolecular signal transduction of Two-Component regulatory system2007

    • Author(s)
      Shiro, Y.
    • Organizer
      International Symposium on Biological Application of Vibrational Spectroscopy
    • Place of Presentation
      Harima, Japan
    • Year and Date
      2007-03-03
    • Data Source
      KAKENHI-PROJECT-16074217
  • [Presentation] 二成分系酸素センサー蛋白質の分子内,分子間情報伝達機構2007

    • Author(s)
      城 宜嗣, 他3名
    • Organizer
      第7回日本蛋白質科学会年会
    • Place of Presentation
      仙台,日本
    • Year and Date
      2007-05-25
    • Data Source
      KAKENHI-PROJECT-16074217
  • [Presentation] Inter-domain and Inter-molecular Signaling Pathway in Two Component System: Histidine Kinase and Response Regulator2007

    • Author(s)
      Shiro, Y.
    • Organizer
      9th International Conference on Biology and Synchrotron Radiation
    • Place of Presentation
      Manchester, UK
    • Year and Date
      2007-08-14
    • Data Source
      KAKENHI-PROJECT-16074217
  • [Presentation] Bio-conversion of substances and information by metal-containing proteins and enzymes2007

    • Author(s)
      Shiro Y
    • Organizer
      3rd International Symposium on Chemistry of Coordination Space (ISCCS 2007)
    • Place of Presentation
      Awaji, Japan
    • Year and Date
      2007-12-10
    • Data Source
      KAKENHI-PROJECT-16074217
  • [Presentation] Structural biology in RIKEN SPring-8 Center: Metal-containing enzymes and proteins2007

    • Author(s)
      Shiro Y
    • Organizer
      BNL-RIKEN Life Science Workshop
    • Place of Presentation
      New York, USA
    • Year and Date
      2007-09-20
    • Data Source
      KAKENHI-PROJECT-16074217
  • [Presentation] Cytochrome P450: Its variety and vitality2007

    • Author(s)
      Shiro, Y.
    • Organizer
      67th Okazaki Conference on Molecular Science and Chemical Biology of Biomolecular Function
    • Place of Presentation
      Okazaki, Japan
    • Year and Date
      2007-11-11
    • Data Source
      KAKENHI-PROJECT-16074217
  • [Presentation] 酸素添加酵素による物質変換の分子科学2007

    • Author(s)
      城 宜嗣
    • Organizer
      分子研研究会「ヘム代謝に関わる酵素の分子科学」
    • Place of Presentation
      岡崎,日本
    • Year and Date
      2007-03-19
    • Data Source
      KAKENHI-PROJECT-16074217
  • [Presentation] Reaction Mechanism of Heme-containing Oxygenases Based on Their Molecular Structures2006

    • Author(s)
      Shiro Y, Sugimoto H
    • Organizer
      20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
    • Place of Presentation
      Kyoto
    • Year and Date
      2006-06-01
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16074217
  • [Presentation] Reaction Mechanism oi Heme-containing Oxygenases Based on Their Molecular Structures2006

    • Author(s)
      Shiro Y, Sugimoto H
    • Organizer
      20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
    • Place of Presentation
      Kyoto
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16074217
  • [Presentation] これからの生物無機化学 ー金属タンパク質の過去と未来ー

    • Author(s)
      城 宜嗣
    • Organizer
      第87回日本生化学会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-15 – 2014-10-18
    • Invited
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Presentation] Bacterial Nitrite Reductase and Nitric Oxide Reductase; NO Generation, Channeling and Decomposition

    • Author(s)
      Shiro, Y.
    • Organizer
      Eighth International Conference on Porphyrins and Phtalocyanines (ICPP8)
    • Place of Presentation
      Istanbul, Turky
    • Year and Date
      2014-06-22 – 2014-06-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-26620140
  • [Presentation] これからの生物無機化学 ー金属タンパク質の過去と未来ー

    • Author(s)
      城 宜嗣
    • Organizer
      第87回日本生化学会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-15 – 2014-10-18
    • Invited
    • Data Source
      KAKENHI-PROJECT-26620140
  • [Presentation] Generation, Channeling and Decomposition of NO in Bacterial System

    • Author(s)
      Shiro, Y.
    • Organizer
      “Metals in Biology” Gordon Research Conference
    • Place of Presentation
      Ventura, USA
    • Year and Date
      2015-01-25 – 2015-01-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Presentation] これからの生物無機化学 ー金属タンパク質の過去と未来ー

    • Author(s)
      城 宜嗣
    • Organizer
      第87回日本生化学会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-15 – 2014-10-18
    • Invited
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Presentation] Bacterial Nitrite Reductase and Nitric Oxide Reductase; NO Generation, Channeling and Decomposition

    • Author(s)
      Shiro, Y.
    • Organizer
      Eighth International Conference on Porphyrins and Phtalocyanines (ICPP8)
    • Place of Presentation
      Istanbul, Turky
    • Year and Date
      2014-06-22 – 2014-06-27
    • Invited
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Presentation] Generation, Channeling and Decomposition of NO in Bacterial System

    • Author(s)
      Shiro, Y.
    • Organizer
      “Metals in Biology” Gordon Research Conference
    • Place of Presentation
      Ventura, USA
    • Year and Date
      2015-01-25 – 2015-01-30
    • Invited
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Presentation] Generation, Propagation and Decomposition of Nitric Oxide in Bacterial Denitrification

    • Author(s)
      Shiro, Y.
    • Organizer
      18th European Bioenergetics Conference (EBEC 2014)
    • Place of Presentation
      Lisbon, Portugal
    • Year and Date
      2014-07-12 – 2014-07-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Presentation] Bacterial Nitrite Reductase and Nitric Oxide Reductase; NO Generation, Channeling and Decomposition

    • Author(s)
      Shiro, Y.
    • Organizer
      Eighth International Conference on Porphyrins and Phtalocyanines (ICPP8)
    • Place of Presentation
      Istanbul, Turky
    • Year and Date
      2014-06-22 – 2014-06-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Presentation] Generation, Channeling and Decomposition of NO in Bacterial System

    • Author(s)
      Shiro, Y.
    • Organizer
      “Metals in Biology” Gordon Research Conference
    • Place of Presentation
      Ventura, USA
    • Year and Date
      2015-01-25 – 2015-01-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-26620140
  • [Presentation] Generation, Propagation and Decomposition of Nitric Oxide in Bacterial Denitrification

    • Author(s)
      Shiro, Y.
    • Organizer
      18th European Bioenergetics Conference (EBEC 2014)
    • Place of Presentation
      Lisbon, Portugal
    • Year and Date
      2014-07-12 – 2014-07-17
    • Invited
    • Data Source
      KAKENHI-PLANNED-22105012
  • [Presentation] Generation, Propagation and Decomposition of Nitric Oxide in Bacterial Denitrification

    • Author(s)
      Shiro, Y.
    • Organizer
      18th European Bioenergetics Conference (EBEC 2014)
    • Place of Presentation
      Lisbon, Portugal
    • Year and Date
      2014-07-12 – 2014-07-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-26620140
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