Kitamura Daisuke 北村大介

… Alternative Names

DAISUKE Kitamura 北村大介

KITAMURA Daisuke 北村大介

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Researcher Number	70204914
Other IDs
Affiliation (Current)	2024: 東京理科大学, 研究推進機構生命医科学研究所, 教授
Affiliation (based on the past Project Information) *help	2015 – 2024: 東京理科大学, 研究推進機構生命医科学研究所, 教授 2012 – 2014: 東京理科大学, 生命医科学研究所, 教授 2008 – 2011: Tokyo University of Science, 生命科学研究所, 教授 2006 – 2007: 東京理科大学, 薬学部, 教授 1998 – 2005: Science University of Tokyo, Research Institute for Biological Sciences, Profess, 生命科学研究所, 教授 … More 1995 – 1996: Tokyo Science University, Institute of Life Science, Professor, 生命科学研究所, 教授 1995: 東京理科大, 生命科学研究所, 教授 1994: 九州大学, 生体防御医学研究所, 助教授 1994: 九州大学, 生医研, 助手 1993: 九州大学, 生体防御医学研究所感染防御部門, 助手 1991 – 1993: 九州大学, 生体防御医学研究所, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Immunology / Biological Sciences / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Immunology / Basic Section 49070:Immunology-related / Transformative Research Areas, Section (III) Except Principal Investigator Immunology / Basic veterinary science/Basic zootechnical science / Basic Section 49070:Immunology-related / 内分泌・代謝学
Keywords	Principal Investigator B細胞 / 免疫学 / 胚中心 / シグナル伝達 / 抗原受容体 / 記憶B細胞 / 免疫記憶 / 免疫応答 / B細胞分化 / Lyn … More / HS1 / 自己免疫疾患 / プラズマ細胞 / 体細胞突然変異 / BASH / アポトーシス / 自己寛容 / 癌 / アダプター蛋白 / BLNK / ジーンターゲティング / IgA腎症 / 自己抗体 / B cell development / 抗体 / Bリンパ球 / receptor editing / ノックアウトマウス / IgA / T細胞 / がん / antigen receptor / 自己免疫 / BCR / BP1 / gene targeting / lambda5 / IgE / アレルギー / 細胞分化 / 免疫学的記憶 / 自己免疫病 / T細胞依存性免疫応答 / プレB細胞レセプター / 形質細胞 / 感染症 / HIV-1 / 後天性免疫不全症候群 / B細胞初期分化 / HPK1 / 対立遺伝子排除 / レセプターエディティング / B細胞抗原受容体 / 非受容体型チロシンキナーゼ / リンパ球分化 / チロシンキナーゼ / 抗体産生 / DNase1L3 / T細胞非依存的免疫応答 / 自然感作 / Th2 / 共生細菌 / 常在細菌 / 交差反応 / 分化誘導 / 胚中心B細胞 / リコール応答 / 腫瘍浸潤T細胞 / がん免疫療法 / がん抗原 / ネオセルフ抗原 / 腫瘍浸潤B細胞 / 免疫寛容 / BCL6 / 解糖系 / ミトコンドリア代謝 / メモリーB細胞 / エフェクター細胞 / self tolerance / adaptor proteins / B cells / self-tolerance / autoimmune disease / protein kinase C / DT40 / トレランス / NF-κB / PKC / 自己トレランス / protein kinase C(PKC) / knock-out mouse / pre-B cell / aminopeptidase A / エクトエンザイム / プレB細胞 / ジーンターゲッティング / アミノペプチダーゼA / apoptos / Thnmice slslction / muM / pre-B cell receptor / 膜型μ鎖 / 遺伝子再構成 / 膜型mu鎖 / 胸腺細胞選択 / μM / λ5 / プレB細胞レセブター / IgE陽性B細胞 / 獲得免疫 / 胚中印 / 親和性成熟 / B 細胞 / エンドサイトーシス / プレB 細胞レセプター / B リンパ球 / B 細胞分化 / 細胞増殖 / 急性リンパ性白血病 / 癌抑制遺伝子 / 白血病 / 遺伝子 / 免疫グロブリン遺伝子 / トランスジェニックマウス / エンハンサー / LTR / プロウィルス / Blk / Bik / sIgH / 標的組換え … More Except Principal Investigator HS1 / シグナル伝達 / Signal transduction / 抗原受容体 / IgE receptor / マスト細胞 / アレルギー / Lyn / c-Myc / p27 / Bリンパ球 / 遺伝子標的法 / エンハンサー / 免疫グロブリン遺伝子 / トランスジェニックマウス / ヘテロクロマチン / 相分離 / Histone H1 / DNase１ / DNase γ / DNase1L3 / tumor / natural killer T cell / natural killer cell / mast cell / signal transduction / cytokine / allergy / NKT細胞 / NK細胞 / メモリー細胞 / 癌 / ナチュラルキラーT細胞 / ナチュラルキラー細胞 / IgE受容体 / サイトカイン / Mast cells / Allergy / IgEレセプター / cell cycle / antigen receptor / CDK inhibitor / cell death / B lymphocyte / Cdkインヒビター / p21 / 増殖 / 誘導的発現 / CDK / 細胞周期 / CDKインヒビター / 細胞死 / Autoimmune disease / Apoptosis / Lyn kinase / Tyrosin kinase / Antigen-receptor / GeNe-targeting / 免疫異常症 / リンパ球分化 / チロシンリン酸化 / Two-hybrid-system / HS1タンパク / 非受容体型チロシンキナーゼ / 自己免疫病 / アポトーシス / Lynキナーゼ / チロシンキナーゼ / 情報伝達 / NOD mouse / autoimmunity / B lymphocytes / insulitis / Diabetes / STO細胞 / Embryonic stem cell / lprマウス / NODマウス / 自己免疫 / 膵島炎 / 糖尿病 / HS1-deficient mouse / Gene targeting / Transcriptional control / Enhancer / Antigen receptor / Gene expression / ジーントラップ / 遺伝子再構成 / 遺伝子転写制御 / ジーンターゲティング / HS1遺伝子欠損マウス / 転写制御 / 遺伝子発現 / gene expression / Transgenic mouse / silencer / enhancer / Immunoglobulin gene / 転写調節 / サイレンサ- / イントロン・エンハンサ- / 遺伝子発現調節 / サイレンサー / T細胞レセプタートランスジェニックマウス / CD8陽性T細胞 / CD40 / CD28 / 補助シグナル / リコンビナントウィルス / ワクチン / 肝臓型マラリア / 疾患モデル / 多段階発癌 / 癌抑制遺伝子 / 癌遺伝子 / ノックアウトマウス Less

Mechanisms of oral commensal bacteria-induced autoimmunity in IgA-nephropathy mouse modelPrincipal Investigator
- Principal Investigator
  
  北村大介
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Tokyo University of Science
自己に内包される共生細菌のMyD88を介した認識とIgE自然抗体産生抑制のメカニズムPrincipal Investigator
- Principal Investigator
  
  北村大介
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Tokyo University of Science
Mechanisms of DNase1L3 action in B cells for induction of T-cell-independent immune responses.Principal Investigator
- Principal Investigator
  
  北村大介
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Tokyo University of Science
Elucidation of spatiotemporal control mechanism of dead cell DNA degrading enzymes by phase separation
- Principal Investigator
  
  水田龍信
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Tokyo University of Science
Mechanisms for induction and regulation of memory B cell subsets exhibiting distinct recall responsesPrincipal Investigator
- Principal Investigator
  
  Kitamura Daisuke
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Tokyo University of Science
A study of pathogenic B-cell memory function and its regulation using an autoimmune IgA nephropathy mouse modelPrincipal Investigator
- Principal Investigator
  
  Kitamura Daisuke
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Tokyo University of Science
Identification of neoself antigens that tumor-infiltrating B cells presentPrincipal Investigator
- Principal Investigator
  
  北村大介
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Science
Mechanisms for de-tolerance spreading of B cells in autoimmune diseasesPrincipal Investigator
- Principal Investigator
  
  Kitamura Daisuke
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Tokyo University of Science
Identification of neo-self tumor antigens recognized by tumor-infiltrating B cells.Principal Investigator
- Principal Investigator
  
  北村大介
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Science
Functional analysis of memory B cells as the effector cellsPrincipal Investigator
- Principal Investigator
  
  Kitamura Daisuke
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Tokyo University of Science
Regulation of B-cell memory formation by metabolic programsPrincipal Investigator
- Principal Investigator
  
  Kitamura Daisuke
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Immunology
- Research Institution
  Tokyo University of Science
Mechanisms for the acquisition of somatic hypermutation activity during the late B cell developmentPrincipal Investigator
- Principal Investigator
  
  Kitamura Daisuke
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Immunology
- Research Institution
  Tokyo University of Science
二次リンパ組織において記憶B細胞の時空間的制御を担う支持細胞の同定Principal Investigator
- Principal Investigator
  
  北村大介
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Science
胚中心B細胞から記憶B細胞への運命決定機構Principal Investigator
- Principal Investigator
  
  北村大介
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Science
A study of the regulational mechanisms for IgE+ B cell development and maintenancePrincipal Investigator
- Principal Investigator
  
  KITAMURA DAISUKE
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Tokyo University of Science
Molecular analyses of B-cell memory development through synthetic immunologyPrincipal Investigator
- Principal Investigator
  
  KITAMURA Daisuke
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Immunology
- Research Institution
  Tokyo University of Science
胚中心におけるB細胞の自己識別および寛容誘導の分子機構Principal Investigator
- Principal Investigator
  
  北村大介
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Science
Molecular mechanisms for affinity-based selection, development and maintenance of memory B cells.Principal Investigator
- Principal Investigator
  
  KITAMURA Daisuke
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Tokyo University of Science
抗原受容体のエンドサイトーシスとシグナル伝達の相互制御機構の解明Principal Investigator
- Principal Investigator
  
  北村大介
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Science
胚中心におけるB細胞の自己識別および寛容誘導の分子機構Principal Investigator
- Principal Investigator
  
  北村大介
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Science
Regulation of B-cell proliferation and differentiation by reorganization of receptor-signal transduction machinery.Principal Investigator
- Principal Investigator
  
  DAISUKE Kitamura
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Tokyo University of Science
プレB細胞受容体シグナル伝達異常による白血病の多段階発がん機構Principal Investigator
- Principal Investigator
  
  北村大介
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Science
抗原受容体シグナル制御による免疫記憶の増強Principal Investigator
- Principal Investigator
  
  北村大介
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Science
抗原受容体シグナル制御による免疫記憶の増強Principal Investigator
- Principal Investigator
  
  北村大介
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Science
宿主B細胞を利用したHIV-1遺伝子高頻度突然変異誘導機構Principal Investigator
- Principal Investigator
  
  北村大介
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Science
Corss-talk of signals between immunoreceptors and cytokine receptors for development of allergy
- Principal Investigator
  
  GOITSUKA Ryo
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Tokyo University of Science
Signal Regulation Mechanisms for B Cell Development and Self-Tolerance Establishment.Principal Investigator
- Principal Investigator
  
  KITAMURA Daisuke
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Immunology
- Research Institution
  Tokyo University of Science
宿主B細胞を利用したHIV-1遺伝子高頻度突然変異誘導機構Principal Investigator
- Principal Investigator
  
  北村大介
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Science
B細胞分化・多様化を制御する抗原受容体シグナルにおけるBASH/BLNKの役割Principal Investigator
- Principal Investigator
  
  北村大介
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Science
B細胞分化・多様化を制御する抗原受容体シグナルにおけるBASH/BLNKの役割Principal Investigator
- Principal Investigator
  
  北村大介
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Science
Regulation of development of type I allergy by the signal transducer specific for the high-affinity IgE receptor
- Principal Investigator
  
  RYO Goitsuka
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Tokyo University of Sciences
肝臓型マラリア原虫感染に対する免疫応答機構の解析
- Principal Investigator
  
  安部良
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tokyo University of Science
Analysis of B-cell antigen receptor signal regulation and dys-regulation emerged as autoimmune diseasesPrincipal Investigator
- Principal Investigator
  
  KITAMURA Daisuke
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Immunology
- Research Institution
  Science University of Tokyo
Study of CDK inhibitors in B cell immune response
- Principal Investigator
  
  TSUBATA Takeshi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Immunology
- Research Institution
  Medical Research Intitute, Tokyo Medical and Dental University
標的遺伝子組換えによる変異マウスを用いたリンパ球シグナル伝達の研究Principal Investigator
- Principal Investigator
  
  北村大介
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo University of Science
標的遺伝子組換えによる変異マウスを用いたB細胞シグナル伝達の研究Principal Investigator
- Principal Investigator
  
  北村大介
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo University of Science
標的遺伝子組換えによる変異マウスを用いたB細胞シグナル伝達の研究Principal Investigator
- Principal Investigator
  
  北村大介
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
遺伝子導入動物による発癌の研究
- Principal Investigator
  
  樋野興夫
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Japanese Foundation For Cancer Research
Analysis of the signal transducing mechanism which leads to the antigenspecific activation or cell death of the lymphocytes.
- Principal Investigator
  
  WATANABE Takeshi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Medical Institute of Bioregulation
A study of BP1 function in lymphocyte development through a generation of BP1-gene knock-out mice.Principal Investigator
- Principal Investigator
  
  KITAMURA Daisuke
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  SCIENCE UNIVERSITY OF TOKYO
  Kyushu University
標的遺伝子組換えによる変異マウスの作製とこれを用いたB細胞シグナル伝達の研究Principal Investigator
- Principal Investigator
  
  北村大介
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
Functional analysis of infiltrating lymphocytes in islets of NODmice by using gene targeting.
- Principal Investigator
  
  NAGAFUCHI Seiho
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Kyushu University
Research on the regulatory mechanism of immunoglobulin gene expression and recombination by means of gene targeting.
- Principal Investigator
  
  WATANABE Takeshi
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  KYUSHU UNIVERSITY
Research on the B cell development using mutant mice generated through gene targeting.Principal Investigator
- Principal Investigator
  
  KITAMURA Daisuke
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  KYUSHU UNIVERSITY
Identification of Transcriptional Factor(s) which regulates Ig gene expression
- Principal Investigator
  
  NAKASHIMA Manabu
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  KYUSYU UNIVERSITY

[Book] 分子細胞生物学事典2013
- Author(s)
  北村大介（分担）
- Total Pages
  580
- Publisher
  医学評論社
- Data Source
  KAKENHI-PROJECT-22390097
[Book] 岩波生物学辞典第5版2013
- Author(s)
  北村大介（分担）
- Total Pages
  2192
- Publisher
  岩波書店
- Data Source
  KAKENHI-PROJECT-24659225
[Book] 分子細胞生物学事典2013
- Author(s)
  北村大介（分担）
- Total Pages
  580
- Publisher
  医学評論社
- Data Source
  KAKENHI-PROJECT-24659225
[Book] 岩波生物学辞典第5版2013
- Author(s)
  北村大介、他多数
- Total Pages
  2192
- Publisher
  岩波書店
- Data Source
  KAKENHI-PROJECT-24659225
[Book] 岩波生物学辞典　第５版2013
- Author(s)
  北村大介（分担）
- Total Pages
  2192
- Publisher
  岩波書店
- Data Source
  KAKENHI-PROJECT-22390097
[Book] II 型 T細胞非依存性抗原による記憶 B 細胞の自己寛容誘導.臨床免疫・アレルギー科2012
- Author(s)
  羽生田圭、北村大介
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-22390097
[Book] How the Immune System Recognizes Self and Nonself: Immunoreceptors and Their Signaling2007
- Author(s)
  Daisuke Kitamura
- Total Pages
  251
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-18012043
[Book] Self-nonself recognition through B-cell antigen receptor. In : Kitamura, D. eds. How the Immune System Recognizes Self and Nonself : Immunoreceptors and Their Signaling2007
- Author(s)
  Kitamura, D.
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-19390141
[Book] How the Immune System Recognizes Self and Nonself: Immunoreceptors and Their Signaling2007
- Author(s)
  Daisuke Kitamura
- Total Pages
  251
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-19390141
[Book] 「抗原受容体シグナル伝達とB細胞分化・活性化」免疫応答と免疫病態の統合的分子理解2007
- Author(s)
  北村大介
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-19390141
[Book] 日本臨床増刊「臨床免疫学(上)-基礎研究の進歩と最新の臨床-」2005
- Author(s)
  北村大介
- Total Pages
  710
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-17047037
[Book] キーワードで理解する免疫学イラストマップ2004
- Author(s)
  北村大介
- Total Pages
  236
- Publisher
  羊土社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207015
[Journal Article] Identification of IgA autoantibodies targeting mesangial cells redefines the pathogenesis of IgA nep2023
- Author(s)
  Nihei, Y., Haniuda, K., Higashiyama, M., Asami, S., Iwasaki, H., Fukao, Y., Nakayama, M., Suzuki, H., Kikkawa, M., Kazuno, S., Miura, Y., Suzuki, Y., Kitamura, D.
- Journal Title
  
  Science Advances
  
  Volume: 9 Issue: 12
- DOI
  10.1126/sciadv.add6734
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00510, KAKENHI-PROJECT-20K21533
[Journal Article] Commensal bacteria and the lung environment are responsible for Th2-mediated memory yielding natural IgE in MyD88-deficient mice.2023
- Author(s)
  Amano, S., Haniuda, K., Fukao, S., Aoki, H., Ueha, S., Kitamura, D.
- Journal Title
  
  Journal of Immunology
  
  Volume: 210 Issue: 7 Pages: 959-972
- DOI
  10.4049/jimmunol.2200888
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21533
[Journal Article] cis interaction of CD153 with TCR/CD3 is crucial for the pathogenic activation of senescence-associated T cells2022
- Author(s)
  Fukushima Yuji、Sakamoto Keiko、Matsuda Michiyuki、Yoshikai Yasunobu、Yagita Hideo、Kitamura Daisuke、Chihara Misaki、Minato Nagahiro、Hattori Masakazu
- Journal Title
  
  Cell Reports
  
  Volume: 40 Issue: 12 Pages: 111373-111373
- DOI
  10.1016/j.celrep.2022.111373
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19455, KAKENHI-PROJECT-20K21533
[Journal Article] Integrin CD11b provides a new marker of pre-germinal center IgA+ B cells in murine Peyer's patches.2022
- Author(s)
  Gao P, Adachi T, Okai S, Morita N, Kitamura D, Shinkura R.
- Journal Title
  
  International Immunology
  
  Volume: 34 Issue: 5 Pages: 249-262
- DOI
  10.1093/intimm/dxab113
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21533, KAKENHI-PROJECT-20K16276, KAKENHI-PROJECT-20H00510
[Journal Article] RelB contributes to the survival, migration and lymphomagenesis of B cells with constitutively active CD40 signaling.2022
- Author(s)
  Kuhn LB, Valentin S, Stojanovic K, Strobl DC, Babushku T, Wang Y, Rambold U, Scheffler L, Grath S, John-Robbert D, Blum H, Feuchtinger A, Blutke A, Weih F, Kitamura D, Rad R, Strobl LJ, Zimber-Strobl U.
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13 Pages: 913275-913275
- DOI
  10.3389/fimmu.2022.913275
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21533
[Journal Article] An IL-9-pulmonary macrophage axis defines the allergic lung inflammatory environment.2022
- Author(s)
  Fu, Y., Wang, J., Zhou, B., Pajulas, A., Gao, H., Ramdas, B., Koh, B., Ulrich, B.J., Yang, S., Kapur, R., Renauld, J.-C., Paczesny, S., Liu, Y., Tighe, R.M., Licona-Limon, P., Flavell, R.A., Takatsuka, S., Kitamura, D., Tepper, R.S., Sun, J., and Kaplan, M.H.
- Journal Title
  
  Science Immunology
  
  Volume: 7 Issue: 68
- DOI
  10.1126/sciimmunol.abi9768
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00510, KAKENHI-PROJECT-20K21533
[Journal Article] C/EBPβ induces B‐cell acute lymphoblastic leukemia and cooperates with <i>BLNK</i> mutations2021
- Author(s)
  Kurata Morito、Onishi Iichiro、Takahara Tomoko、Yamazaki Yukari、Ishibashi Sachiko、Goitsuka Ryo、Kitamura Daisuke、Takita Junko、Hayashi Yasuhide、Largaesapda David A、Kitagawa Masanobu、Nakamura Takuro
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 12 Pages: 4920-4930
- DOI
  10.1111/cas.15164
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01035, KAKENHI-PROJECT-20H00510, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-21H02372, KAKENHI-PROJECT-20K08744, KAKENHI-PROJECT-20K21533, KAKENHI-PROJECT-21K19405, KAKENHI-PROJECT-21K15414
[Journal Article] MicroRNA-directed pathway discovery elucidates an miR-221/222-mediated regulatory circuit in class switch recombination.2021
- Author(s)
  Wigton, E.J., Mikami, Y., McMonigle, R.J., Castellanos, C.A., Wade-Vallance, A.K., Zhou, S.K., Kageyama, R., Litterman, A., Roy, S., Kitamura, D., Dykhuizen, E.C., Allen, C.D.C., Hu, H., O'Shea, J.J., Ansel, K.M.
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 218 Issue: 11
- DOI
  10.1084/jem.20201422
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00510, KAKENHI-PROJECT-20K21533
[Journal Article] Protein kinase Cδ is essential for the IgG response against T-cell-independent type 2 antigens and commensal bacteria.2021
- Author(s)
  Fukao, S., Haniuda, K., Tamaki, H. and Kitamura, D.
- Journal Title
  
  eLife
  
  Volume: 10
- DOI
  10.7554/elife.72116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00510, KAKENHI-PROJECT-20K21533
[Journal Article] Mechanisms for the regulation of memory B-cell recall responses in mice.2021
- Author(s)
  Kitamura, D.
- Journal Title
  
  International Immunology
  
  Volume: 33 Issue: 12 Pages: 791-796
- DOI
  10.1093/intimm/dxab042
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00510, KAKENHI-PROJECT-20K21533
[Journal Article] A novel cancer immunotherapy using tumor-infiltrating B cells in the APCmin/+ mouse model.2021
- Author(s)
  Wang X., Asami, S. and Kitamura D.
- Journal Title
  
  PLoS ONE
  
  Volume: 16 Issue: 1 Pages: e0245608-e0245608
- DOI
  10.1371/journal.pone.0245608
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21533, KAKENHI-PUBLICLY-19H04818, KAKENHI-PROJECT-20H00510
[Journal Article] Multi-faceted regulation of IgE production and humoral memory formation2021
- Author(s)
  Haniuda, K. and Kitamura, D.
- Journal Title
  
  Allergol. Int.
  
  Volume: 70 Issue: 2 Pages: 163-168
- DOI
  10.1016/j.alit.2020.11.002
- NAID
  130008024333
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00510, KAKENHI-PROJECT-20K21533
[Journal Article] Metabolic reprogramming induces germinal center B cell differentiation through Bcl6 locus remodeling.2020
- Author(s)
  Haniuda, K., Fukao, S. and Kitamura, D.
- Journal Title
  
  Cell Reports
  
  Volume: 33 Issue: 5 Pages: 108333-108333
- DOI
  10.1016/j.celrep.2020.108333
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21533, KAKENHI-PUBLICLY-19H04818, KAKENHI-PROJECT-20H00510, KAKENHI-PROJECT-19K16700
[Journal Article] Tracing self-reactive B cells in normal mice.2020
- Author(s)
  Nojima, T., Reynolds, A.E., Kitamura, D., Kelsoe, G. and Kuraoka, M.
- Journal Title
  
  The Journal of Immunology
  
  Volume: 205 Issue: 1 Pages: 90-101
- DOI
  10.4049/jimmunol.1901015
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21533, KAKENHI-PUBLICLY-19H04818, KAKENHI-PROJECT-20H00510
[Journal Article] Ubiquitination of IgG1 cytoplasmic tail modulates B-cell signalling and activation2020
- Author(s)
  Kodama Tadahiro、Hasegawa Mika、Sakamoto Yui、Haniuda Kei、Kitamura Daisuke
- Journal Title
  
  International Immunology
  
  Volume: - Issue: 6 Pages: 385-395
- DOI
  10.1093/intimm/dxaa009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H05072, KAKENHI-PROJECT-17J07038, KAKENHI-PROJECT-18K19461, KAKENHI-PROJECT-20K21533, KAKENHI-PUBLICLY-19H04818, KAKENHI-PROJECT-20H00510
[Journal Article] Induced Germinal Center B Cell Culture System2019
- Author(s)
  Haniuda Kei、Kitamura Daisuke
- Journal Title
  
  BIO-PROTOCOL
  
  Volume: 9 Issue: 4 Pages: 3163-3163
- DOI
  10.21769/bioprotoc.3163
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H05072, KAKENHI-PROJECT-17K19573, KAKENHI-PUBLICLY-19H04818, KAKENHI-PROJECT-18K19461
[Journal Article] PRMT5 is essential for B cell development and germinal center dynamics.2019
- Author(s)
  Litzler, L.C., Zahn, A., Meli, A.P., Hebert, S., Patenaude, A., Methot, S.P., Sprumont, A., Bois, T., Kitamura, D., Costantino, S., King, I.L., Kleinman, C.L., Richard, S., Di Noia, J.M.
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 22-22
- DOI
  10.1038/s41467-018-07884-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19461, KAKENHI-PUBLICLY-17H05803, KAKENHI-PROJECT-16H05206
[Journal Article] Molecular design, optimization, and genomic integration of chimeric B cell receptors in murine B cells.2019
- Author(s)
  Pesch, T., Bonati, L., Kelton, W., Parola, C., Ehling, R.A., Cseprgi, L., Kitamura, D., Reddy, S.T.
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 10 Pages: 2630-2630
- DOI
  10.3389/fimmu.2019.02630
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04818
[Journal Article] The quantity of CD40 signaling determines the differentiation of B cells into functionally distinct memory cell subsets.2019
- Author(s)
  Koike, T., Harada, K., Horiuchi, S., Kitamura, D.
- Journal Title
  
  eLife
  
  Volume: 8
- DOI
  10.7554/elife.44245
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H04818, KAKENHI-PROJECT-18K19461
[Journal Article] Cross-reactivity to kynureninase tolerizes B cells that express the HIV-1 broadly neutralizing antibody 2F5.2019
- Author(s)
  Finney, J., Yang, G., Kuraoka, M., Song, S., Nojima, T., Verkoczy, L., Kitamura, D., Haynes, B.F., Kelsoe, G.
- Journal Title
  
  The Journal of Immunology
  
  Volume: 203 Issue: 12 Pages: 3268-3281
- DOI
  10.4049/jimmunol.1900069
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19461
[Journal Article] Transcription Factor STAT3 Serves as a negative regulator controlling IgE class switching in mice.2018
- Author(s)
  Dascani, P., Ding, C., Kong, K., Tieri, D., Hu, X., Zhang, H., Kitamura, D., Bolli, R., Rouchka, E.C., Yan, J.
- Journal Title
  
  ImmunoHorizens
  
  Volume: 2 Issue: 11 Pages: 349-362
- DOI
  10.4049/immunohorizons.1800069
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19461, KAKENHI-PUBLICLY-17H05803, KAKENHI-PROJECT-16H05206
[Journal Article] A splenic IgM memory subset with antibacterial specificities is sustained from persistent mucosal responses.2018
- Author(s)
  Le Gallou, S., Zhou, Z., Thai, L.H., Fritzen, R., de Los Aires, A.V., Megret, J., Yu, P., Kitamura, D., Bille, E., Tros, F., Nassif, X., Charbit, A., Weller, S., Weill, J.C. and Reynaud, C.A.
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 215 Issue: 8 Pages: 2035-2053
- DOI
  10.1084/jem.20180977
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19461, KAKENHI-PUBLICLY-17H05803, KAKENHI-PROJECT-16H05206
[Journal Article] Cbl ubiquitin ligases control B cell exit from the germinal-center reaction.2018
- Author(s)
  Li, X., Gadzinsky, A., Gong, L., Tong, H., Calderon, V., Li, Y., Kitamura, D., Klein, U., Langdon, W.Y., Hou, F., Zou, Y.R. and Gu, H.
- Journal Title
  
  Immunity
  
  Volume: 48 Issue: 3 Pages: 530-541
- DOI
  10.1016/j.immuni.2018.03.006
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05803, KAKENHI-PROJECT-16H05206, KAKENHI-PROJECT-16K15295
[Journal Article] IL-9 receptor signaling in memory B cells regulates humoral recall responses.2018
- Author(s)
  Takatsuka, S., Yamada, H., Haniuda, K., Saruwatari, H., Ichihashi, M., Renauld, J.-C. and Kitamura, D.
- Journal Title
  
  Nature Immunology
  
  Volume: 19 Issue: 9 Pages: 1025-1034
- DOI
  10.1038/s41590-018-0177-0
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19461, KAKENHI-PUBLICLY-17H05803, KAKENHI-PROJECT-16H05206, KAKENHI-PROJECT-17H05072, KAKENHI-PROJECT-17K19573
[Journal Article] Host DNases prevent vascular occlusion by neutrophil extracellular traps2017
- Author(s)
  Jimenez-Alcazar Miguel、Rangaswamy Chandini、Panda Rachita、Bitterling Josephine、Simsek Yashin J.、Long Andy T.、Bilyy Rostyslav、Krenn Veit、Renn? Christoph、Renn? Thomas、Kluge Stefan、Panzer Ulf、Mizuta Ryushin、Mannherz Hans Georg、Kitamura Daisuke、Herrmann Martin、Napirei Markus、Fuchs Tobias A.
- Journal Title
  
  Science
  
  Volume: 358 Issue: 6367 Pages: 1202-1206
- DOI
  10.1126/science.aam8897
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08891, KAKENHI-PUBLICLY-17H05803, KAKENHI-PROJECT-16H05206, KAKENHI-PROJECT-16K15295
[Journal Article] The AID-Cre-ERT2 model: A tool for monitoring B cell immune responses and generating selective hybridomas.2017
- Author(s)
  Le Gallou, S., Nojima, T., Kitamura, D., Weill, J.C. and Reynaud, C.A.
- Journal Title
  
  Methods Mol. Biol.
  
  Volume: 1623 Pages: 243-251
- DOI
  10.1007/978-1-4939-7095-7_19
- ISBN
  9781493970940, 9781493970957
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05803, KAKENHI-PROJECT-16H05206, KAKENHI-PROJECT-16K15295
[Journal Article] In Vitro-Induced Germinal Center B Cell Culture System2017
- Author(s)
  Haniuda Kei, Nojima Takuya and Kitamura Daisuke
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 1623 Pages: 125-133
- DOI
  10.1007/978-1-4939-7095-7_11
- ISBN
  9781493970940, 9781493970957
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19573, KAKENHI-PUBLICLY-17H05803, KAKENHI-PROJECT-16H05206, KAKENHI-PROJECT-17H05072, KAKENHI-PROJECT-16K15295
[Journal Article] BCR and endosomal TLR signals synergize to increase AID expression and establish central B cell tolerance.2017
- Author(s)
  Kuraoka, M., Snowden, P.B., Nojima, T., Verkoczy, L., Haynes, B.F., Kitamura, D., Kelsoe, G.
- Journal Title
  
  Cell Reports
  
  Volume: 18 Issue: 7 Pages: 1627-1635
- DOI
  10.1016/j.celrep.2017.01.050
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05206, KAKENHI-PROJECT-16K15295
[Journal Article] Differing requirements for MALT1 function in peripheral B cell survival and differentiation.2017
- Author(s)
  Lee, P., Zhu, Z., Hachmann, J., Nojima, T., Kitamura, D., Salvesen, G., Rickert, R.C.
- Journal Title
  
  The Journal of Immunology
  
  Volume: 198 Issue: 3 Pages: 1066-1080
- DOI
  10.4049/jimmunol.1502518
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05206, KAKENHI-PROJECT-16K15295
[Journal Article] Complex Antigens Drive Permissive Clonal Selection in Germinal Centers.2016
- Author(s)
  Kuraoka, M., Schmidt, A.G., Nojima, T., Feng, F., Watanabe, A., Kitamura, D., Harrison, S.C., Kepler, T.B. and Kelsoe, G.
- Journal Title
  
  Immunity
  
  Volume: 44 Issue: 3 Pages: 542-552
- DOI
  10.1016/j.immuni.2016.02.010
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670239, KAKENHI-PROJECT-25293116
[Journal Article] IFN-γ receptor and STAT1 signaling in B cells are central to spontaneous germinal center formation and autoimmunity.2016
- Author(s)
  Domeier, P.P., Chodisetti, S.B., Soni, C., Schell, S.L., Elias, M.J., Wong, E.B., Cooper, T.K., Kitamura, D., Rahman, Z.S.
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 213 Issue: 5 Pages: 715-732
- DOI
  10.1084/jem.20151722
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05206, KAKENHI-PROJECT-16K15295
[Journal Article] Autonomous membrane IgE signaling prevents IgE-memory formation.2016
- Author(s)
  Haniuda, K., Fukao, S., Kodama, T., Hasegawa, H., Kitamura, D.
- Journal Title
  
  Nature Immunology
  
  Volume: 17 Issue: 9 Pages: 1109-1117
- DOI
  10.1038/ni.3508
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05206, KAKENHI-PROJECT-16H07238, KAKENHI-PROJECT-15K19138, KAKENHI-PROJECT-16K15295
[Journal Article] 膜型IgEの自発的シグナル伝達によるB細胞記憶形成の制御2016
- Author(s)
  羽生田圭、深尾紗央里、北村大介
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 65 Pages: 329-333
- Data Source
  KAKENHI-PROJECT-25293116
[Journal Article] 膜型IgEの自発的シグナル伝達によるB細胞記憶形成の制御2016
- Author(s)
  羽生田圭、深尾紗央里、北村大介
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 65 Pages: 329-333
- Data Source
  KAKENHI-PROJECT-26670239
[Journal Article] DNase γ, DNase I and caspase-activated DNase cooperate to degrade dead cells.2016
- Author(s)
  Koyama, R., Arai, T., Kijima, M., Sato, S., Miura, S., Yuasa, M., Kitamura, D., Mizuta, R.
- Journal Title
  
  Genes to Cells
  
  Volume: 21 Issue: 11 Pages: 1150-1163
- DOI
  10.1111/gtc.12433
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05206, KAKENHI-PROJECT-16K15295
[Journal Article] GIMAP1 Is Essential for the Survival of Naive and Activated B Cells In Vivo.2016
- Author(s)
  Webb, L.M., Datta, P., Bell, S.E., Kitamura, D., Turner, M. and Butcher, G.W.
- Journal Title
  
  The Journal of Immunology
  
  Volume: 196 Issue: 1 Pages: 207-216
- DOI
  10.4049/jimmunol.1501582
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670239, KAKENHI-PROJECT-25293116
[Journal Article] Ex vivo engineered immune organoids for controlled germinal center reactions.2015
- Author(s)
  Purwada, A., Jaiswal, M.K., Ahn, H., Nojima, T., Kitamura, D., Gaharwar, A.K., Cerchietti, L. and Singh, A.
- Journal Title
  
  Biomaterials
  
  Volume: 63 Pages: 24-34
- DOI
  10.1016/j.biomaterials.2015.06.002
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670239, KAKENHI-PROJECT-25293116
[Journal Article] JNK Regulatory Molecule G5PR Induces IgG Autoantibody-Producing Plasmablasts from Peritoneal B1a Cells.2015
- Author(s)
  Kitabatake M, Soma M, Zhang T, Kuwahara K, Fukushima Y, Nojima T, Kitamura D, Sakaguchi N.
- Journal Title
  
  J Immunol.
  
  Volume: 194 Issue: 4 Pages: 1480-1488
- DOI
  10.4049/jimmunol.1401127
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24590388, KAKENHI-PUBLICLY-25111512, KAKENHI-PUBLICLY-25118730, KAKENHI-PROJECT-25293116, KAKENHI-PROJECT-25460337, KAKENHI-PROJECT-25860813, KAKENHI-PROJECT-26670239, KAKENHI-PROJECT-15K10083
[Journal Article] A novel and effective cancer immunotherapy mouse model using antigen-specific B cells selected in vitro.2014
- Author(s)
  Moutai T, Yamana H, Nojima T and Kitamura D.
- Journal Title
  
  PLOS ONE
  
  Volume: 9 Issue: 3 Pages: 92732-92732
- DOI
  10.1371/journal.pone.0092732
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J08179, KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24659225, KAKENHI-PUBLICLY-25111512, KAKENHI-PUBLICLY-25118730, KAKENHI-PROJECT-25293116
[Journal Article] Gp49B-mediated negative regulation of antibody production by memory and marginal zone B cells.2014
- Author(s)
  Fukao S, Haniuda K, Nojima T, Takai T, Kitamura D.
- Journal Title
  
  J Immunol.
  
  Volume: 193 Issue: 2 Pages: 635-644
- DOI
  10.4049/jimmunol.1302772
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24249016, KAKENHI-PUBLICLY-25111512, KAKENHI-PUBLICLY-25118730, KAKENHI-PROJECT-25293116, KAKENHI-PROJECT-26670230, KAKENHI-PROJECT-26670239
[Journal Article] Spleen supports a pool of innate-like B cells in white adipose tissue that protects against obesity-associated insulin resistance2014
- Author(s)
  Wu L, Parekh V V, Hsiao J, Kitamura D, Van Kaer L.
- Journal Title
  
  Proc Natl Acad Sci USA.
  
  Volume: 111 Issue: 43 Pages: 4638-4647
- DOI
  10.1073/pnas.1324052111
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PUBLICLY-25111512, KAKENHI-PUBLICLY-25118730, KAKENHI-PROJECT-25293116, KAKENHI-PROJECT-26670239
[Journal Article] DNase γ Is the Effector Endonuclease for Internucleo- somal DNA Fragmentation in Necrosis2013
- Author(s)
  Mizuta R., Araki S., Furukawa M., Furukawa Y., Ebara S., Shiokawa D., Hayashi K., Tanuma S., and Kitamura D
- Journal Title
  
  PLoS One
  
  Volume: 8(12) Issue: 12 Pages: 1-8
- DOI
  10.1371/journal.pone.0080223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300365, KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24590587, KAKENHI-PROJECT-24659225, KAKENHI-PUBLICLY-25111512, KAKENHI-PUBLICLY-25118730, KAKENHI-PROJECT-25293116, KAKENHI-PROJECT-25460156
[Journal Article] Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis.2013
- Author(s)
  Caganova M, Carrisi C, Varano G, Mainoldi F, Zanardi F, Germain PL, George L, Alberghini F, Ferrarini L, Talukder AK, Ponzoni M, Testa G, Nojima T, Doglioni C, Kitamura D,
- Journal Title
  
  J Clin Invest
  
  Volume: 123 Issue: 12 Pages: 5009-5022
- DOI
  10.1172/jci70626
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24659225, KAKENHI-PUBLICLY-25111512, KAKENHI-PUBLICLY-25118730, KAKENHI-PROJECT-25293116
[Journal Article] Syk-dependent signaling pathways in neutrophils and macrophages are indispensable in the pathogenesis of anti-collagen antibody-induced arthritis.2012
- Author(s)
  Naoko Ozaki
- Journal Title
  
  International Immunology
  
  Volume: 24 Issue: 9 Pages: 539-550
- DOI
  10.1093/intimm/dxs078
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390097, KAKENHI-PROJECT-22590435, KAKENHI-PROJECT-24659225
[Journal Article] Identification of CMTM7 as a Transmembrane Linker of BLNK and the B-cell Receptor2012
- Author(s)
  北村大介, 宮崎敦子, 典後沢里美, 他
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 2 Pages: e31829-e31829
- DOI
  10.1371/journal.pone.0031829
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021042, KAKENHI-PROJECT-22390097
[Journal Article] A novel mechanism for the autonomous termination of pre-B cell receptor expression via induction of lysosomal-associated protein transmembrane 5.2012
- Author(s)
  Yohei Kawano
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 32 Issue: 21 Pages: 4462-4471
- DOI
  10.1128/mcb.00531-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390097, KAKENHI-PROJECT-22590445, KAKENHI-PROJECT-23790530, KAKENHI-PROJECT-24659225
[Journal Article] E2A and CBP/p300 act in synergy to promote chromatin accessibility of the immunoglobulin | locus.2012
- Author(s)
  Sakamoto, S., ffakae, K., Anzai, Y., Murai, K., Tamaki, N., Miyazaki, M., Miyazaki, K., Romanow, W. J., Ikawa, T., Kitamura, D., Yanagihira, I., Minato, N., Murre, C., Agata, Y
- Journal Title
  
  J. Immunol
  
  Volume: 188 Issue: 11 Pages: 5547-5560
- DOI
  10.4049/jimmunol.1002346
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19059008, KAKENHI-PROJECT-22390097, KAKENHI-PUBLICLY-23118515, KAKENHI-PROJECT-23390068, KAKENHI-PROJECT-23591609, KAKENHI-PLANNED-24111008, KAKENHI-PROJECT-24659225, KAKENHI-PROJECT-24689042, KAKENHI-ORGANIZER-24111001
[Journal Article] SLP-76 is required for high-affinity IgE receptor- and IL-3 receptor-mediated activation of basophils.2012
- Author(s)
  Shinya Hidano
- Journal Title
  
  International Immunology
  
  Volume: 24 Issue: 11 Pages: 719-727
- DOI
  10.1093/intimm/dxs072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390097, KAKENHI-PROJECT-24659225
[Journal Article] Tolerance induction of IgG+memory B cells by T-cell independent type II antigens.2011
- Author(s)
  Haniuda, K., Nojima, T., Ohyama, K. and Kitamura, D.
- Journal Title
  
  J. Immunol.
  
  Volume: 186 Pages: 5620-5628
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390097
[Journal Article] In-vitro derived germinal centre B ceils differentially generate memory B or plasma cells in vivo2011
- Author(s)
  北村大介, 野嶋卓也, 羽生田圭, 他
- Journal Title
  
  Nature Communications
  
  Volume: 2 Issue: 1 Pages: 465-465
- DOI
  10.1038/ncomms1475
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021042, KAKENHI-PROJECT-22390097
[Journal Article] Tolerance induction of IgG+ memory B cells by T-cell independent type II antigens2011
- Author(s)
  北村大介, 羽生田圭, 野嶋卓也, 大山亨
- Journal Title
  
  The Journal of Immunology
  
  Volume: 186 Pages: 5620-5628
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021042
[Journal Article] Tolerance induction of IgG+ memory B cells by T-cell independent type II antigens2011
- Author(s)
  北村大介, 羽生田圭, 野嶋卓也, 大山亨介
- Journal Title
  
  The Journal of Immunology
  
  Volume: 186 Pages: 5620-5628
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390097
[Journal Article] プレB細胞レセプターシグナルによるL鎖遺伝子再構成の誘導機構2010
- Author(s)
  北村大介
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 54 Pages: 1-8
- Data Source
  KAKENHI-PROJECT-22390097
[Journal Article] プレB細胞レセプターシグナルによるL鎖遺伝子再構成の誘導機構2010
- Author(s)
  北村大介
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 54 Pages: 1-8
- Data Source
  KAKENHI-PUBLICLY-21113526
[Journal Article] プレB細胞レセプターシグナルによるL鎖遺伝子再構成の誘導機構2010
- Author(s)
  北村大介
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 54 Pages: 1-8
- Data Source
  KAKENHI-PUBLICLY-22021042
[Journal Article] BLNK binds active H-Ras to promote B cell receptor-mediated capping and ERK activation2009
- Author(s)
  Imamura, Y., Oda, A., Katahira, T., Bundo, K., Pike, K.A., Ratcliffe, M.J.H. and Kitamura, D.
- Journal Title
  
  J. Biol. Chem. 284
  
  Pages: 9804-9813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390141
[Journal Article] BLNK suppresses pre-B cell leukemogenesisthrough inhibition of JAK32009
- Author(s)
  Nakayama, J., Yamamoto, M., Hayashi, K., Satoh, H., Bundo, K., Kubo, M., Goitsuka, R., Farrar, M. A. and Kitamura D.
- Journal Title
  
  Blood 113
  
  Pages: 1483-1492
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390141
[Journal Article] Possible contribution of DNase γ to immunoglobulin V gene diversification2009
- Author(s)
  Okamoto, N., Okamoto, M., Araki, S., Arakawa, H., Mizuta, R. and Kitamura, D.
- Journal Title
  
  Immunol. Lett. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390141
[Journal Article] PKCη directs induction of IRF-4 expression and Ig κ gene rearrangement in pre-BCR signaling pathway2008
- Author(s)
  Oda, A., Ono, T., Yamamoto, M., Goitsuka, R. and Kitamura, D.
- Journal Title
  
  Int. Immunol 20
  
  Pages: 1417-1426
- NAID
  10024357764
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390141
[Journal Article] Hematopoietic lineage cell-specific protein-1 (HS1) regulates PAR-mediated ERK activation and thromboxane generation in platelets2008
- Author(s)
  Kahner, B. N., Dorsam, R. T., Kim, S., Shankar, H., Kitamura, D., Kunapuli, S. P.
- Journal Title
  
  Platelets 19
  
  Pages: 614-623
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390141
[Journal Article] Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals2008
- Author(s)
  Shinohara, M., Koga, T., Okamoto, K., Sakaguchi, S., Arai, K., Yasuda, H., Takai, T., Kodama, T., Morio, T,. Geha, R. S., Kitamura, D., Kurosaki, T., Ellmeier, W. and Takayanagi, H.
- Journal Title
  
  Cell 132
  
  Pages: 794-806
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390141
[Journal Article] Distinct regulatory functions of SLP-76 and MIST in NK cell cytotoxicity and IFN-γ production2008
- Author(s)
  Hidano, S., Sasanuma, H., Ohshima, K., Seino, K.-I., Kumar, L., Hayashi, K., Hikida, M., Kurosaki, T., Taniguchi, M., Geha, R. S., Kitamura, D. and Goitsuka, R.
- Journal Title
  
  Int. Immunol 20
  
  Pages: 345-352
- NAID
  10021239822
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390141
[Journal Article] Stage-specific expression of DNase gamma during B-cell development and its role in B-cell receptor-mediated apoptosis in WEHI-231 cells.2007
- Author(s)
  Daisuke Shiokawa
- Journal Title
  
  Cell Death Differ. 14
  
  Pages: 992-1000
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390141
[Journal Article] Hematopoietic lineage cell specific protein 1 (HS1) is a functionally important signaling molecule in platelet activation2007
- Author(s)
  Kahner, B.N., Dorsam, R.T., Mada, S.R., Kim, S., Stalker, T.J., Brass, L.F., Daniel, J.L., Kitamura, D. and Kunapuli, S.P.
- Journal Title
  
  Blood 110
  
  Pages: 2449-2456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390141
[Journal Article] Stage-specific expression of DNase gamma during B-cell development and its role in B-cell receptor-mediated apoptosis in WEHI-231 cells2007
- Author(s)
  Shiokawa, D., Shika, Y., Araki, S., Sunaga, S., Mizuta, R., Kitamura, D. and Tanuma, S.
- Journal Title
  
  Cell Death Differ 14
  
  Pages: 992-1000
- Data Source
  KAKENHI-PROJECT-19390141
[Journal Article] Stage-specific expression of DNase gamma during B-cell development and its role in B-cell receptor-mediated apoptosis in WEHI-231 cells.2007
- Author(s)
  Daisuke Shiokawa
- Journal Title
  
  Cell Death Differ. 14
  
  Pages: 992-1000
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18012043
[Journal Article] Chicken cathelicidin-B1, an antimicrobial guardian at the mucosal M cell gateway2007
- Author(s)
  Goitsuka, R., Chen, C.L., Benyon, L., Asano, Y., Kitamura, D. and Cooper, M.D.
- Journal Title
  
  Proc. Natl. Acad. Sci.USA. 104
  
  Pages: 15063-15068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390141
[Journal Article] Involvement of DNase γ in the resected double-strand DNA breaks in immunoglobulin genes.2005
- Author(s)
  Okamoto, M., Okamoto, N., Yashiro, H., Shiokawa, D., Sunaga, S., Yoshimori, A., Tanuma, S., Kitamura, D.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 327
  
  Pages: 76-83
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207015
[Journal Article] Transcriptional regulation of SLP-76 family hematopoietic cell adaptor MIST/Clnk by STAT5.2004
- Author(s)
  Sasanuma, H., Tatsuno, A., Tsuji, K., Hidano, S., Morita, S., Kitamura, T., Kubo, M., Kitamura, D., Goitsuka, R.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 321(1)
  
  Pages: 145-153
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207015
[Journal Article] Impaired receptor editing in the primary B cell repertoire of BASH-deficient mice.2004
- Author(s)
  Hayashi, K., Nojima, T., Goitsuka, R., Kitamura.D.
- Journal Title
  
  J.Immunol. 173(10)
  
  Pages: 5980-5988
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207015
[Journal Article] Transcriptional regulation of SLP-76 family hematopoietic cell adaptor MIST/Clnk by STAT5.2004
- Author(s)
  Sasanuma, H., Tatsuno, A., Tsuji, K., Hidano, S., Kitamura, T., Kuno, M., Kitamura, D., Goitsuka, R.
- Journal Title
  
  Biochem.Biophys.Res.Comm. 321
  
  Pages: 145-153
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14206034
[Journal Article] Impaired receptor editing in the primary B cell repertoire of BASH-deficient mice.2004
- Author(s)
  Hayashi, K, Nojima, T, Goitsuka R, Kitamura, D.
- Journal Title
  
  J.Immunol. 173
  
  Pages: 5980-5988
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14206034
[Journal Article] BASH-deficient mice : limited primary repertoire and antibody formation, but sufficient affinity maturation and memory B cell generation, in anti-NP response.2004
- Author(s)
  Yamamoto, M, Nojima, T, Hayashi, K, Goitsuka, R, Furukawa, K, Azuma, T, Kitamura, D.
- Journal Title
  
  Int.Immunol. 16
  
  Pages: 1161-1171
- NAID
  10013425465
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14206034
[Journal Article] Identification and Characterization of a Novel BASH N-terminus Associated Protein, BNAS2.2004
- Author(s)
  Imamura Y., Katahira, T., Kitamura, D.
- Journal Title
  
  J.Biol.Chem. 279(25)
  
  Pages: 26425-26432
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207015
[Journal Article] BASH-deficient mice : Limited primary repertoire and antibody formation, but sufficient affinity maturation and memory B cell generation, in anti-NP response.2004
- Author(s)
  Yamamoto, M., Nojima, T., Hayashi, K., Goitsuka, R., Furukawa, K., Azuma, T., Kitamura, D.
- Journal Title
  
  Int.Immunol. 16(8)
  
  Pages: 1161-1171
- NAID
  10013425465
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207015
[Journal Article] Atomic force microscopy analysis of rolling circle amplification of plasmid PNA.2003
- Author(s)
  Mizuta R., Mizuta, M., Kitamura, D.
- Journal Title
  
  Arch.Histol.Cytol. 66(2)
  
  Pages: 175-181
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207015
[Journal Article] Distinct signaling requirements for Dμ selection, IgH allelic exclusion, pre-B cell transition, and tumor suppression in B cell progenitors.2003
- Author(s)
  Hayashi, K., Yamamoto, M., Nojima, T., Goitsuka, R., Kitamura, K.
- Journal Title
  
  Immunity 18
  
  Pages: 825-836
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14206034
[Journal Article] Induction of protective immunity by primed B-1 cells in Toxoplasma gondii-infected B cell-deficient mice.2003
- Author(s)
  Chen, M., Mun, H.S., Piao, L.X., Aosai, F., Norose, K., Mohamed, R.M., Belal, U.S., Fang, H., Ahmed, A.K., Kang, H.K., Matsuzaki, G., Kitamura, D., Yano, A.
- Journal Title
  
  Microbiol.Immunol. 47(12)
  
  Pages: 997-1003
- NAID
  50000360286
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207015
[Journal Article] Targeting of MIST to Src-family kinases via SKAP55-SLAP-130 adaptor complex in mast cells.2003
- Author(s)
  Fujii, Y., Wakahara, S., Nakao, T., Hara, T., Ohtake, H., Komurasaki, T., Kitamura, K., Tatsuno, A., Fujiwara, N., Hozumi, N., Ra, C., Kitamura, D., Goitsuka, R.
- Journal Title
  
  FEBS Letters 540
  
  Pages: 111-116
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14206034
[Journal Article] Distinct signaling requirements for Dμ selection, IgH allelic exclusion, pre-B cell transition and tumor suppression in B-cell progenitors.2003
- Author(s)
  Hayashi, K., Yamamoto, M., Nojima, T., Goitsuka, R., Kitamura, D.
- Journal Title
  
  Immunity 18(6)
  
  Pages: 825-836
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207015
[Journal Article] Regulation of Vav Localization in Membrane Rafts by Adaptor Molecules Grb2 and BLNK.2003
- Author(s)
  Johmura, S., Oh-hora, M., Inabe, K., Nishikawa, Y., Hayashi, K., Vigorito, E., Kitamura, D., Turner, M., Shingu, K., Hikida, M., Kurosaki, T.
- Journal Title
  
  Immunity 18(6)
  
  Pages: 777-787
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207015
[Journal Article] Molecular visualization of immunoglobulin switch region RNA/DNA complex by atomic force microscope.2003
- Author(s)
  Mizuta, R., Iwai, K., Shigeno, M., Mizuta, M., Uemura, T., Ushiki, T., Kitamura, D.
- Journal Title
  
  J.Biol.Chem. 278
  
  Pages: 4431-4434
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207015
[Journal Article] Targeting of MIST to Src-family kinases via SKAP55-SLAP-130 adaptor complex in mast cells.2003
- Author(s)
  Fujii, Y., Wakahara, S., Nakao, T., Hara, T., Ohtake, H., Komurasaki, T., Kitamura, K., Tatsuno, A., Fujiwara, N., Hozumi, N., Ra, C., Kitamura, D., Goitsuka, R.
- Journal Title
  
  FEBS Lett. 540
  
  Pages: 111-116
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207015
[Journal Article] RAG2 is down-regulated by cytoplasmic sequestration and ubiquitin-dependent degradation.2002
- Author(s)
  Mizuta, R., Mizuta, M., Araki, S., Kitamura, D.
- Journal Title
  
  J.Biol.Chem. 277(44)
  
  Pages: 41423-41427
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207015
[Journal Article] SMAD1 signaling is critical for initial commitment of germ cell lineage from mouse epiblast.2002
- Author(s)
  Hayashi K, Kobayashi T, Umino T, Goitsuka, R, Matsui Y, Kitamura D.
- Journal Title
  
  Mech.Dev. 118
  
  Pages: 99-109
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14206034
[Patent] IgA腎症に関連する自己抗体2021
- Inventor(s)
  北村大介，鈴木祐介，二瓶義人
- Industrial Property Rights Holder
  北村大介，鈴木祐介，二瓶義人
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-20H00510
[Patent] IgA腎症に関連する自己抗体2021
- Inventor(s)
  北村大介，鈴木祐介，二瓶義人
- Industrial Property Rights Holder
  北村大介，鈴木祐介，二瓶義人
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-20K21533
[Patent] 特定抗原特異的抗体を産生する細胞のスクリーニング方法2018
- Inventor(s)
  馬渡達也, 中石智之, 北寛, 吉田慎一, 北野光昭, 北村大介
- Industrial Property Rights Holder
  馬渡達也, 中石智之, 北寛, 吉田慎一, 北野光昭, 北村大介
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-235794
- Filing Date
  2018
- Data Source
  KAKENHI-PUBLICLY-17H05803
[Patent] Ｂ細胞集団の製造方法、及びそれを用いたモノクローナル抗体の製造方法2017
- Inventor(s)
  北村大介，馬渡達也，中石智之，北寛士，北野光昭
- Industrial Property Rights Holder
  北村大介，馬渡達也，中石智之，北寛士，北野光昭
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-004860
- Filing Date
  2017-01-16
- Data Source
  KAKENHI-PROJECT-16H05206
[Patent] Ｂ細胞集団の製造方法、及びそれを用いたモノクローナル抗体の製造方法2017
- Inventor(s)
  北村大介，馬渡達也，中石智之，北寛士，北野光昭
- Industrial Property Rights Holder
  北村大介，馬渡達也，中石智之，北寛士，北野光昭
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-004860
- Filing Date
  2017-01-16
- Data Source
  KAKENHI-PROJECT-16K15295
[Patent] B細胞集団の製造方法2014
- Inventor(s)
  北村大介、中石智之
- Industrial Property Rights Holder
  学校法人東京理科大学、株式会社カネカ
- Industrial Property Rights Type
  特許
- Filing Date
  2014-07-02
- Data Source
  KAKENHI-PUBLICLY-25118730
[Patent] B細胞集団の製造方法2014
- Inventor(s)
  北村大介、中石智之
- Industrial Property Rights Holder
  学校法人東京理科大学、株式会社カネカ
- Industrial Property Rights Type
  特許
- Filing Date
  2014-07-02
- Data Source
  KAKENHI-PROJECT-26670239
[Patent] 抗原特異的B細胞集団の製造方法2010
- Inventor(s)
  北村大介
- Industrial Property Rights Holder
  東京理科大学
- Filing Date
  2010-10-25
- Overseas
- Data Source
  KAKENHI-PROJECT-22390097
[Patent] 抗原特異的B細胞集団の製造方法2010
- Inventor(s)
  北村大介
- Industrial Property Rights Holder
  東京理科大学
- Filing Date
  2010-10-25
- Overseas
- Data Source
  KAKENHI-PUBLICLY-22021042
[Patent] 抗原特異的 B 細胞集団の製造方法2010
- Inventor(s)
  北村大介
- Industrial Property Rights Holder
  東京理科大学
- Filing Date
  2010-10-25
- Overseas
- Data Source
  KAKENHI-PROJECT-22390097
[Patent] 抗原特異的B細胞集団の製造方法2009
- Inventor(s)
  北村大介, 野嶋卓也
- Industrial Property Rights Holder
  東京理科大学
- Industrial Property Number
  2009-251362
- Filing Date
  2009-10-30
- Data Source
  KAKENHI-PUBLICLY-21113526
[Patent] 抗原特異的B細胞集団の製造方法2009
- Inventor(s)
  北村大介, 野嶋卓也
- Industrial Property Rights Holder
  東京理科大学
- Filing Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-20060025
[Presentation] Identification of IgA autoantibodies against glomerular mesangial cells and the target autoantigen using an IgA nephropathy mouse model2022
- Author(s)
  Yoshihito Nihei, Kei Haniuda, Mizuki Higashiyama, Hiroyuki Iwasaki, Shohei Asami, Yusuke Suzuki, Daisuke Kitamura
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20H00510
[Presentation] A mechanism for anti-mesangium IgA production in an IgA nephropathy mouse model2022
- Author(s)
  Mizuki Higashiyama, Kei Haniuda, Yoshihito Nihei, Riku Hisato, Daisuke Kitamura
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20K21533
[Presentation] Identification of IgA autoantibodies against glomerular mesangial cells and the target autoantigen using an IgA nephropathy mouse model2022
- Author(s)
  Yoshihito Nihei, Kei Haniuda, Mizuki Higashiyama, Hiroyuki Iwasaki, Shohei Asami, Yusuke Suzuki, Daisuke Kitamura
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20K21533
[Presentation] A mechanism for anti-mesangium IgA production in an IgA nephropathy mouse model2022
- Author(s)
  Mizuki Higashiyama, Kei Haniuda, Yoshihito Nihei, Riku Hisato, Daisuke Kitamura
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20H00510
[Presentation] B細胞におけるIgE産生制御2021
- Author(s)
  北村大介
- Organizer
  第7回総合アレルギー講習会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21533
[Presentation] IgA腎症におけるIgA自己抗体産生2021
- Author(s)
  北村大介、二瓶義人、東山瑞希、岩崎裕幸、久斗陸、羽生田圭、鈴木祐介
- Organizer
  第85回日本インターフェロン・サイトカイン学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21533
[Presentation] Pathogenic antibody production by microbiota in an IgA nephropathy mouse model.2021
- Author(s)
  北村大介
- Organizer
  5th Symposium of the International Immunological Memory and Vaccine Forum
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00510
[Presentation] Pathogenic antibody production by microbiota in an IgA nephropathy mouse model.2021
- Author(s)
  北村大介
- Organizer
  5th Symposium of the International Immunological Memory and Vaccine Forum
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21533
[Presentation] B細胞におけるIgE産生制御2021
- Author(s)
  北村大介
- Organizer
  第7回総合アレルギー講習会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00510
[Presentation] IgA腎症におけるIgA自己抗体産生2021
- Author(s)
  北村大介、二瓶義人、東山瑞希、岩崎裕幸、久斗陸、羽生田圭、鈴木祐介
- Organizer
  第85回日本インターフェロン・サイトカイン学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00510
[Presentation] Characteristics of naive and germinal center B cells in murine IgA nephropathy.2019
- Author(s)
  Yoshihito Nihei, Kei Haniuda, Hitoshi Suzuki, Toshiki Kano, Yusuke Fukao, Daisuke Kitamura, Yusuke Suzuki
- Organizer
  International Society of Nephrology World Congress of Nephrology 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19461
[Presentation] Mechanisms for Memory B-Cell Formation and Function: Possible Implications for Vaccination.2019
- Author(s)
  Daisuke Kitamura
- Organizer
  The 3rd Annual Chiba University-UCSD Symposium on Mucosal Immunology, Allergy and Vaccines.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19461
[Presentation] Commensal bacteria-dependent IgA+ Plasmablasts secrete autoantibodies against glomerular antigens in a mouse model for IgAN.2019
- Author(s)
  Shohei Asami, Yoshihito Nihei, Kei Haniuda, Mizuki Higashiyama, Yusuke Suzuki, Daisuke Kitamura
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19461
[Presentation] Memory B cell generation and response.2019
- Author(s)
  北村大介
- Organizer
  The 30th Anniversary International Symposium of Research Institute for Biomedical Sciences, Tokyo University of Science
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19461
[Presentation] ベーシックシンポジウム2:B細胞2019
- Author(s)
  北村大介
- Organizer
  第47回日本臨床免疫学会総会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04818
[Presentation] ベーシックシンポジウム２：B細胞2019
- Author(s)
  北村大介
- Organizer
  第47回日本臨床免疫学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19461
[Presentation] Mechanisms for Memory B-Cell Formation and Function: Possible Implications for Vaccination.2019
- Author(s)
  Daisuke Kitamura
- Organizer
  The 3rd Annual Chiba University-UCSD Symposium on Mucosal Immunology, Allergy and Vaccines
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05206
[Presentation] Characteristics of B cells in IgA Nephropathy model mice.2019
- Author(s)
  Yoshihito Nihei, Kei Haniuda, Hitoshi Suzuki, Toshiki Kano, Yusuke Fukao, Daisuke Kitamura, Yusuke Suzuki
- Organizer
  Kidney week 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19461
[Presentation] Memory B cell generation and response.2019
- Author(s)
  北村大介
- Organizer
  The 30th Anniversary International Symposium of Research Institute for Biomedical Sciences, Tokyo University of Science
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04818
[Presentation] Mechanisms for Memory B-Cell Formation and Function: Possible Implications for Vaccination.2019
- Author(s)
  Daisuke Kitamura
- Organizer
  The 3rd Annual Chiba University-UCSD Symposium on Mucosal Immunology, Allergy and Vaccines
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05803
[Presentation] Therapeutic potential of tumor-infiltrating B cells.2018
- Author(s)
  Shohei Asami, Nguyen T. Dat, Xinying Wang, Dominika Papiernik, Toshihiro Suzuki, Tetsuya Nakatsura and Daisuke Kitamura
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PUBLICLY-17H05803
[Presentation] B細胞による獲得免疫応答とその制御メカニズム2018
- Author(s)
  北村大介
- Organizer
  第4回川島カンファレンス
- Invited
- Data Source
  KAKENHI-PROJECT-18K19461
[Presentation] B細胞による獲得免疫応答とその制御メカニズム2018
- Author(s)
  北村大介
- Organizer
  第4回川島カンファレンス
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05803
[Presentation] Regulatory Mechanisms for Memory B Cell Development and Function.2018
- Author(s)
  Daisuke Kitamura
- Organizer
  KEYSTONE SYMPOSIA, B Cells: Mechanisms in Immunity and Autoimmunity
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05206
[Presentation] IL-9 receptor signaling in memory B cells regulates humoral recall responses.2018
- Author(s)
  Daisuke Kitamura
- Organizer
  2nd International Innovation Dialogue on Genome Engineering Animal Models and Biomedical Research Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05206
[Presentation] IL-9 receptor signaling in memory B cells regulates humoral recall responses.2018
- Author(s)
  Daisuke Kitamura
- Organizer
  2nd International Innovation Dialogue on Genome Engineering Animal Models and Biomedical Research Symposium.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05803
[Presentation] Regulatory Mechanisms for Memory B Cell Development and Function.2018
- Author(s)
  Daisuke Kitamura
- Organizer
  KEYSTONE SYMPOSIA, B Cells: Mechanisms in Immunity and Autoimmunity.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05803
[Presentation] IL-9 receptor signaling in memory B cells regulates humoral recall responses.2018
- Author(s)
  Daisuke Kitamura
- Organizer
  2nd International Innovation Dialogue on Genome Engineering Animal Models and Biomedical Research Symposium.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19461
[Presentation] Characteristics of naive B cells in murine IgA nephropathy.2018
- Author(s)
  Yoshihito Nihei, Kei Haniuda, Mizuki Higashiyama, Yusuke Suzuki and Daisuke Kitamura
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19461
[Presentation] Regulatory Mechanisms for Memory B Cell Development and Function.2018
- Author(s)
  Daisuke Kitamura
- Organizer
  KEYSTONE SYMPOSIA, B Cells: Mechanisms in Immunity and Autoimmunity.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19461
[Presentation] B細胞による獲得免疫応答とその制御メカニズム2018
- Author(s)
  北村大介
- Organizer
  第4回川島カンファレンス
- Invited
- Data Source
  KAKENHI-PROJECT-16H05206
[Presentation] IgE/B細胞メモリー2017
- Author(s)
  北村大介
- Organizer
  第４回総合アレルギー講習会 ~Total Allergistをめざして～
- Invited
- Data Source
  KAKENHI-PROJECT-16H05206
[Presentation] Germinal center B cell development by glycolysis and mitochondrial metabolism.2017
- Author(s)
  Kei Haniuda, Saori Fukao, Daisuke Kitamura
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05206
[Presentation] In vitro 抗体産生細胞作製とがん治療2017
- Author(s)
  北村大介
- Organizer
  東京理科大学・国立がん研究センター合同シンポジウム「ハイパーアシスト医療システム実現に向けて」
- Data Source
  KAKENHI-PUBLICLY-17H05803
[Presentation] Bリンパ球細胞の独自培養技術を活用した新規抗腫瘍薬の開発2017
- Author(s)
  北村大介
- Organizer
  BioJapan 2017
- Data Source
  KAKENHI-PUBLICLY-17H05803
[Presentation] Germinal center B cell development by glycolysis and mitochondrial metabolism.2017
- Author(s)
  Kei Haniuda, Saori Fukao, Daisuke Kitamura
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16K15295
[Presentation] B細胞クローン法のヒトB細胞への応用2017
- Author(s)
  北村大介
- Organizer
  第45回日本臨床免疫学会総会
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05803
[Presentation] How do different classes of B cell receptors signal differently?2016
- Author(s)
  Daisuke Kitamura
- Organizer
  Symposium hosted by Klaus Rajewsky: Mechanisms of Molecular and Cellular Immunity 1964-2016
- Place of Presentation
  Berlin, Germany
- Year and Date
  2016-11-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15295
[Presentation] Regulation of IL-9 receptor expression on B cells during immune response.2016
- Author(s)
  Hiroyuki Yamada, Shogo Takatsuka, Daisuke Kitamura
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター
- Year and Date
  2016-12-06
- Data Source
  KAKENHI-PROJECT-16H05206
[Presentation] B細胞補助受容体CD19による胚中心形成メカニズムの解析2016
- Author(s)
  長谷川仁士、羽生田圭、北村大介
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K15295
[Presentation] How do different classes of B cell receptors signal differently?2016
- Author(s)
  Daisuke Kitamura
- Organizer
  Symposium hosted by Klaus Rajewsky: Mechanisms of Molecular and Cellular Immunity 1964-2016.
- Place of Presentation
  Berlin, Germany
- Year and Date
  2016-11-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05206
[Presentation] The quantity of CD40 signaling in pre-GC phase determine the differentiation into functionally distinct memory B cell subsets via Mef2b expression.2016
- Author(s)
  Takuya Koike, Shu Horiuchi, Kei Haniuda, Daisuke Kitamura
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター
- Year and Date
  2016-12-07
- Data Source
  KAKENHI-PROJECT-16K15295
[Presentation] BLNK-knockout mice as a model of allergic diseases.2015
- Author(s)
  Daisuke Kitamura
- Organizer
  International Symposium of the Center for Animal Disease Models 2015
- Place of Presentation
  Tokyo
- Year and Date
  2015-07-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670239
[Presentation] Autonomous signaling from IgE B cell receptor suppresses B cell memory formation.2015
- Author(s)
  Kei Haniuda, Saori Fukao, Tadahiro Kodama, Hitoshi Hasegawa, Daisuke Kitamura
- Organizer
  The 3rd Symposium of International Immunological Memory and Vaccine Forum.
- Place of Presentation
  Berlin (Germany)
- Year and Date
  2015-10-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293116
[Presentation] Autonomous signaling from IgE B cell receptor suppresses B cell memory formation.2015
- Author(s)
  Kei Haniuda, Saori Fukao, Tadahiro Kodama, Hitoshi Hasegawa, Daisuke Kitamura
- Organizer
  The 3rd Symposium of International Immunological Memory and Vaccine Forum
- Place of Presentation
  Berlin
- Year and Date
  2015-10-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670239
[Presentation] BLNK-knockout mice as a model of allergic diseases.2015
- Author(s)
  Daisuke Kitamura
- Organizer
  International Symposium of the Center for Animal Disease Models 2015.
- Place of Presentation
  学士会館（東京）
- Year and Date
  2015-07-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293116
[Presentation] IgE型B細胞受容体シグナルによるB細胞短命化誘導機構の解明2014
- Author(s)
  茂木瑞恵、羽生田圭、北村大介
- Organizer
  第58回日本薬学会関東支部大会
- Place of Presentation
  昭和薬科大学、町田市、東京
- Year and Date
  2014-10-04
- Data Source
  KAKENHI-PROJECT-25293116
[Presentation] A role of IL-9 receptor on B cells in the T-dependent immune responses.2014
- Author(s)
  Hiroshi Saruwatari, Shogo Takatsuka, Daisuke Kitamura
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  京都国際会館
- Year and Date
  2014-12-11
- Data Source
  KAKENHI-PUBLICLY-25111512
[Presentation] CD40 signaling quantity may determine the fate of germinal center B cells.2014
- Author(s)
  Takuya Koike, Shu Horiuchi, Daisuke Kitamura
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  京都国際会館
- Year and Date
  2014-12-10
- Data Source
  KAKENHI-PUBLICLY-25111512
[Presentation] JNK regulatory molecule G5PR induces peritoneal B1a cells into IgG autoantibody-producing plasmablasts.2014
- Author(s)
  Masahiro Kitabatake, Miho Soma, Tianli Zhang, Takuya Nojima, Daisuke Kitamura, Nobuo Sakaguchi
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  京都国際会館
- Year and Date
  2014-12-12
- Data Source
  KAKENHI-PROJECT-26670239
[Presentation] A role of IL-9 receptor on B cells in the T-dependent immune responses.2014
- Author(s)
  Hiroshi Saruwatari, Shogo Takatsuka, Daisuke Kitamura
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  京都国際会館
- Year and Date
  2014-12-11
- Data Source
  KAKENHI-PROJECT-26670239
[Presentation] CD40 signaling quantity may determine the fate of germinal center B cells.2014
- Author(s)
  Takuya Koike, Shu Horiuchi, Daisuke Kitamura
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  京都国際会館
- Year and Date
  2014-12-10
- Data Source
  KAKENHI-PROJECT-26670239
[Presentation] BLNK regulates IgE B-cell receptor signaling and B-cell memory formation.2014
- Author(s)
  Kei Haniuda, Saori Fukao, Daisuke Kitamura
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  京都国際会館
- Year and Date
  2014-12-11
- Data Source
  KAKENHI-PROJECT-26670239
[Presentation] BLNK regulates IgE B-cell receptor signaling and B-cell memory formation.2014
- Author(s)
  Kei Haniuda, Saori Fukao, Daisuke Kitamura
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  京都国際会館、京都
- Year and Date
  2014-12-11
- Data Source
  KAKENHI-PROJECT-25293116
[Presentation] CD40 signaling quantity may determine the fate of germinal center B cells.2014
- Author(s)
  Takuya Koike, Shu Horiuchi, Daisuke Kitamura
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  京都国際会館
- Year and Date
  2014-12-10
- Data Source
  KAKENHI-PUBLICLY-25118730
[Presentation] Molecular mechanisms for memory B-cell development and function.2013
- Author(s)
  Daisuke Kitamura, Kei Haniuda, Saori Fukao, Mika Inada, Shu Horiuchi, Shogo Takatsuka, Tatsuya Moutai, Takuya Nojima
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PUBLICLY-25111512
[Presentation] Molecular mechanisms for memory B-cell development and function.2013
- Author(s)
  Daisuke Kitamura, Kei Haniuda, Saori Fukao, Mika Inada, Shu Horiuchi, Shogo Takatsuka, Tatsuya Moutai, Takuya Nojima
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-25293116
[Presentation] Molecular requirements for memory B-cell development.2013
- Author(s)
  Daisuke Kitamura
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ，千葉
- Data Source
  KAKENHI-PROJECT-24659225
[Presentation] Molecular requirements for memory B-cell development.2013
- Author(s)
  Daisuke Kitamura
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PROJECT-25293116
[Presentation] Molecular mechanisms for memory B-cell development and function.2013
- Author(s)
  Daisuke Kitamura, Kei Haniuda, Saori Fukao, Mika Inada, Shu Horiuchi, Shogo Takatsuka, Tatsuya Moutai, Takuya Nojima
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-24659225
[Presentation] Molecular mechanisms for memory B-cell development and function.2013
- Author(s)
  Daisuke Kitamura, Kei Haniuda, Saori Fukao, Mika Inada, Shu Horiuchi, Shogo Takatsuka, Tatsuya Moutai, Takuya Nojima
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PUBLICLY-25118730
[Presentation] Regulatory mechanisms for memory B cell development and function2013
- Author(s)
  Daisuke Kitamura
- Organizer
  The 1st Symposium of International Immunological Memory and Vaccine Forum."Immunological Memory and Vaccine"
- Place of Presentation
  東京
- Year and Date
  2013-01-29
- Data Source
  KAKENHI-PROJECT-24659225
[Presentation] Molecular requirements for memory B-cell development.2013
- Author(s)
  Daisuke Kitamura
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PUBLICLY-25118730
[Presentation] Molecular requirements for memory B-cell development.2013
- Author(s)
  Daisuke Kitamura
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PUBLICLY-25111512
[Presentation] Regulatory mechanisms for memory B cell development and function.2013
- Author(s)
  Daisuke Kitamura
- Organizer
  The 1st Symposium of International Immunological Memory and Vaccine Forum.
- Place of Presentation
  東京
- Year and Date
  2013-01-29
- Data Source
  KAKENHI-PROJECT-22390097
[Presentation] Molecular mechanisms for memory B-cell development and function2013
- Author(s)
  Daisuke Kitamura, Kei Haniuda, Saori Fukao, Mika Inada, Shu Horiuchi, Shogo Takatsuka, Tatsuya Moutai, Takuya Nojima
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-24659225
[Presentation] Molecular requirements for memory B-cell development2013
- Author(s)
  Daisuke Kitamura
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ
- Year and Date
  2013-12-13
- Data Source
  KAKENHI-PROJECT-24659225
[Presentation] B細胞免疫応答のin vitro解析とその臨床応用の可能性2012
- Author(s)
  北村大介
- Organizer
  Renal Transplantation Forum 2012
- Place of Presentation
  東京
- Year and Date
  2012-09-01
- Data Source
  KAKENHI-PROJECT-22390097
[Presentation] 誘導性胚中心B細胞を用いた免疫応答機構の解明とその応用2012
- Author(s)
  北村大介
- Organizer
  筑波大学・東京理科大学生命医科学研究所合同シンポジウム
- Place of Presentation
  東京
- Year and Date
  2012-10-19
- Data Source
  KAKENHI-PROJECT-22390097
[Presentation] A new cancer therapy using induced germinal center B cells2012
- Author(s)
  Daisuke Kitamura
- Organizer
  The 3rd Workshop of Synthetic Immunology
- Place of Presentation
  京都
- Year and Date
  2012-05-18
- Data Source
  KAKENHI-PROJECT-24659225
[Presentation] A novel regulatory mechanism for T-dependent immune responses through gp49B.2012
- Author(s)
  Saori Fukao, Kei Haniuda, Toshiyuki Takai, Daisuke Kitamura
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2012-12-05
- Data Source
  KAKENHI-PROJECT-22390097
[Presentation] gp49B regulates antibody production from margmal zone and memory B cells in the immune responses2011
- Author(s)
  北村大介, 深尾紗央里, 羽生田生, 他
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ(千葉県)
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-22390097
[Presentation] 抗原特異的なB細胞を選択的に増殖させる培養系の構築2011
- Author(s)
  北村大介, 山名秀之, 馬渡達也
- Organizer
  第55回日本薬学会関東支部大会
- Place of Presentation
  千葉県船橋市
- Year and Date
  2011-10-08
- Data Source
  KAKENHI-PUBLICLY-22021042
[Presentation] gp49B regulates antibody production from marginal zone and memory B cells in the immune responses.2011
- Author(s)
  Saori Fukao, Kei Haniuda, Toshiyuki Takai, Daisuke Kitamura
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-22390097
[Presentation] B-cell memory generation in induced germinal center B cells2010
- Author(s)
  Daisuke Kitamura
- Organizer
  The 2nd Synthetic Immunology Workshop.
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22390097
[Presentation] T-cell dependent IgG1 B-cell memory is not activated, but tolerized, on binding eith T-cell independent type II antigen.2010
- Author(s)
  Kei Haniuda, Takuya Nojima, Daisuke Kitamura
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  Kobe, Japan.
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PROJECT-22390097
[Presentation] B-cell memory generation in induced germinal center B cells.2010
- Author(s)
  北村大介
- Organizer
  The 2nd Synthetic Immunology Workshop.
- Place of Presentation
  京都
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PUBLICLY-21113526
[Presentation] The germinal center-like B cell culture system revealed that IL-21 reversibly inhibits memory-B-cell generation in vitro.2010
- Author(s)
  Takuya Nojima, Kei Haniuda, Tatsuya Moutai, Ikuo Shiratori, Daisuke Kitamura
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  Kobe, Japan.
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PROJECT-22390097
[Presentation] B-cell memory generation in induced germinal center B cells.2010
- Author(s)
  北村大介
- Organizer
  The 2nd Synthetic Immunology Workshop.
- Place of Presentation
  京都
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PUBLICLY-22021042
[Presentation] Role of the novel transmembrane protein CMTM7 in BCR signal transduction and endocytosis.2010
- Author(s)
  Atsuko Miyazaki, Satomi Yogosawa, Daisuke Kitamura
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  Kobe, Japan.
- Year and Date
  2010-08-23
- Data Source
  KAKENHI-PROJECT-22390097
[Presentation] B-cell memory generation in induced germinal center B cells.2010
- Author(s)
  北村大介
- Organizer
  The 2nd Synthetic Immunology Workshop.
- Place of Presentation
  京都
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-22390097
[Presentation] 抗原受容体シグナル伝達における新規膜タンパク質CMTM7の役割2008
- Author(s)
  宮崎敦子、北村大介
- Organizer
  第38 回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19390141
[Presentation] Meis1欠損マウスにおける胸腺形成異常2008
- Author(s)
  平山雄啓、後飯塚僚、飛騨野真也、河合康洋、丸太博之、北村大介、中村卓郎
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19390141
[Presentation] IL-4 promotes memory-like B cell generation in vitro2008
- Author(s)
  野嶋卓也、白鳥行大、北村大介
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19390141
[Presentation] B細胞初期分化に重要なpre-BCRの発現制御におけるLAPTM5 の役割2008
- Author(s)
  河野洋平、大内田理佳、王継揚、山本睦美、北村大介、烏山一
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19390141
[Presentation] pre-BCRシグナル伝達経路においてIRF-4の発現とL鎖遺伝子再構成はPKCη により誘導される2008
- Author(s)
  小田朗永、小野友宏、山本睦美、後飯塚僚、北村大介
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19390141
[Presentation] SLP-76 is required for the high affinity IgE receptor- and cytokine receptor-induced activation of basophils2008
- Author(s)
  飛騨野真也、有木玲菜、北村大介、後飯塚僚
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19390141
[Presentation] ネクローシスDNA断片化酵素DNaseγの生理的機能2008
- Author(s)
  水田龍信、鈴木浩平、荏原翔太、古川祐樹、北村大介
- Organizer
  第31回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19390141
[Presentation] Toward the establishment of germinal center-like B cell culture system2007
- Author(s)
  野嶋卓也、白鳥行大、北村大介
- Organizer
  第37回日本免疫学会総会・学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19390141
[Presentation] A Gads-binding RXXK motif determines the differential membrane targeting and functions of SLP-76 and MIST in FcεRI signaling in mast cells2007
- Author(s)
  廣田朋子、飛騨野真也、河合康洋、北村大介、後飯塚僚
- Organizer
  第37回日本免疫学会総会・学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19390141
[Presentation] Molecular mechanism of BASH-mediated preBCR down-regulation2007
- Author(s)
  河野洋平、山本睦美、北村大介、烏山一
- Organizer
  第37回日本免疫学会総会・学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19390141
[Presentation] B細胞抗原受容体のエンドサイトーシスに関与するCMTM3/BNAS2 の機能解析2007
- Author(s)
  與五沢里美、引場樹里、北村大介
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390141
[Presentation] DNaseγはネクローシスDNA断片化酵素である2007
- Author(s)
  水田龍信、北村大介
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390141
[Presentation] Molecular mechanisms for the development of B-cell memory.
- Author(s)
  Daisuke Kitamura
- Organizer
  The 2nd Symposium of International Immunological Memory and Vaccine Forum
- Place of Presentation
  La Jolla, USA
- Year and Date
  2014-08-25 – 2014-08-26
- Data Source
  KAKENHI-PROJECT-26670239
[Presentation] Regulatory mechanisms for memory B cell development and function.
- Author(s)
  北村大介
- Organizer
  The 1st Symposium of International Immunological Memory and Vaccine Forum.
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24659225
[Presentation] A novel regulatory mechanism for T-dependent immune responses through gp49B.
- Author(s)
  深尾紗央里、羽生田圭、高井俊之、北村大介
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24659225
[Presentation] Molecular mechanisms for the development of B-cell memory.
- Author(s)
  Daisuke Kitamura
- Organizer
  The 2nd Symposium of International Immunological Memory and Vaccine Forum
- Place of Presentation
  La Jolla Institute of Allergy and Immunology, La Jolla, USA
- Year and Date
  2014-08-25 – 2014-08-26
- Data Source
  KAKENHI-PROJECT-25293116
[Presentation] Molecular mechanisms for the development of B-cell memory
- Author(s)
  Daisuke Kitamura
- Organizer
  The 2nd Symposium of International Immunological Memory and Vaccine Forum
- Place of Presentation
  La Jolla, USA
- Year and Date
  2014-08-25 – 2014-08-26
- Data Source
  KAKENHI-PUBLICLY-25118730
[Presentation] 誘導性胚中心B細胞を用いた免疫応答機構の解明とその応用
- Author(s)
  北村大介
- Organizer
  筑波大学・東京理科大学生命医科学研究所合同シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24659225
[Presentation] Regulatory mechanisms for memory B cell development and function.
- Author(s)
  北村大介
- Organizer
  The 1st Symposium of International Immunological Memory and Vaccine Forum.
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22390097
[Presentation] Molecular mechanisms for the development of B-cell memory.
- Author(s)
  Daisuke Kitamura
- Organizer
  The 2nd Symposium of International Immunological Memory and Vaccine Forum
- Place of Presentation
  La Jolla, USA
- Year and Date
  2014-08-25 – 2014-08-26
- Data Source
  KAKENHI-PUBLICLY-25111512
[Presentation] B細胞免疫応答のin vitro解析とその臨床応用の可能性
- Author(s)
  北村大介
- Organizer
  Renal Transplantation Forum 2012
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-24659225

1. HAYASHI Katsuhiko (20287486)

# of Collaborated Projects: 8 results

# of Collaborated Products: 8 results
2. OKAMOTO Noriaki (10318230)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. RYO Goitsuka (50301552)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
4. IKUO Shiratori (90379090)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. NOJIMA TAKUYA (10434036)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. WATANABE Takeshi (40028684)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. HANIUDA Kei (40734918)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
8. 辻佐智代 (60297629)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. NAKASHIMA Manabu (50198074)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. NAGAFUCHI Seiho (00150441)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TSUBATA Takeshi (80197756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. AIBA Yuichi (00273516)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. ADACHI Takahiro (50222625)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 樋野興夫 (90127910)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 阿部訓也 (40240915)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 松隈章一 (30106166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 徳久剛史 (20134364)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 岩倉洋一郎 (10089120)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 安部良 (20159453)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 上阪等 (00251554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 香山雅子 (80318229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 久保允人 (40277281)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 水田龍信 (50297628)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
24. RETH Michael

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. RAJEWSKY Klaus

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. ZAVALA Fide

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. HOWARD Maure

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 中村卓郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 田沼靖一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 福島祐二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 湊長博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kitamura Daisuke 北村 大介

DAISUKE Kitamura 北村 大介

KITAMURA Daisuke 北村 大介

Research Projects

Research Products

Co-Researchers

Mechanisms of oral commensal bacteria-induced autoimmunity in IgA-nephropathy mouse modelPrincipal Investigator

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自己に内包される共生細菌のMyD88を介した認識とIgE自然抗体産生抑制のメカニズムPrincipal Investigator

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Mechanisms of DNase1L3 action in B cells for induction of T-cell-independent immune responses.Principal Investigator

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Elucidation of spatiotemporal control mechanism of dead cell DNA degrading enzymes by phase separation

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Mechanisms for induction and regulation of memory B cell subsets exhibiting distinct recall responsesPrincipal Investigator

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A study of pathogenic B-cell memory function and its regulation using an autoimmune IgA nephropathy mouse modelPrincipal Investigator

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Identification of neoself antigens that tumor-infiltrating B cells presentPrincipal Investigator

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Mechanisms for de-tolerance spreading of B cells in autoimmune diseasesPrincipal Investigator

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Identification of neo-self tumor antigens recognized by tumor-infiltrating B cells.Principal Investigator

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Functional analysis of memory B cells as the effector cellsPrincipal Investigator

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Regulation of B-cell memory formation by metabolic programsPrincipal Investigator

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Mechanisms for the acquisition of somatic hypermutation activity during the late B cell developmentPrincipal Investigator

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二次リンパ組織において記憶B細胞の時空間的制御を担う支持細胞の同定Principal Investigator

Principal Investigator

Kitamura Daisuke 北村大介

DAISUKE Kitamura 北村大介

KITAMURA Daisuke 北村大介