ADACHI Masaaki 安達正晃

Researcher Number	70240926
Other IDs
Affiliation (based on the past Project Information) *help	2009: 札幌医科大学, 医学部, 研究員 2007 – 2008: Sapporo Medical University, 医学部, 准教授 1999 – 2006: Sapporo Medical University, Sch. Of Med., First Dept. Of Internal Medicine, Associated Professor, 医学部, 助教授 2002: SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE ASOCIATE PROF., 医学部・大学院・医学研究科, 助教授 2002: 札幌医科大学, 大学院・医学部, 助教授 … More 2001: 札幌医科大学, 大学院・医学研究科, 助教授 2000: 札幌医科大学, 医学部, 助手 1995 – 1998: 札幌医科大学, 医学部, 講師 1993 – 1994: 札幌医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / 内科学一般 / Hematology / Pathological medical chemistry / 細胞死(アポトーシス) / Laboratory medicine Except Principal Investigator Radiation science / Radiation science / 内科学一般 / Gastroenterology / Biological Sciences
Keywords	Principal Investigator アポトーシス / BAD / BAG-1 / ヒストンアセチル化 / Metastasis / Apoptosis / Bcl-2 / アノイキス / IL-2 / mitochondria … More / apoptosis / Histone acetylation / CBP / p300 / G-CSF / LC-PTP / ヒストンリン酸化 / DNA修復 / DNA障害 / 放射線 / 放射線照射 / caspase-8 / Cell motility / Anoikis / PKC / SHP-2 / JNK / chromatin / DNA damage / ROS / ヒストンアセチル / chaperone / TOF-Mass / phosphorylation / BH-3 only protein / Akt / BH3-only蛋白 / 14-3-3 / Bcl-xL / ミトコンドリア / BH3 / Cancer therapy / Histone acetyltransferase / Transcriptional activation / HDAC / 癌治療 / HAT / 転写活性 / Golgi apparatus / anoikis / 細胞運動能 / 転移 / Differentiation / WT1 / 蛋白-蛋白相互作用 / 細胞分化 / wt1腫瘍抑制遺伝子 / 分化 / WT1遺伝子 / tyrosine kinase / genome DNA / Chromosome assignment / SHPTP2 / Protein-tyrosine phosphatase / 分子生物学 / 染色体マップ / ホスホチロシン / SH2ドメイン / タンパク質脱リン酸化酵素 / SH-PTP2 / 蛋白質脱リン酸化 / 分子診断 / マイクロRNA / SUVH20 / クロマチン構造 / 酸化ストレス / 小胞体ストレス / ヒストンメチル化 / BH3-only蛋白質 / BH3-only 蛋白質 / TNF / ERK / sulindac / アデノウイルスベクター / Bcl-2 family / 分子標的治療 / PKC alpha / IFN-gamma … More Except Principal Investigator JNK / アポトーシス / 放射線感受性 / 3'-UTR / 5'-UTR / IAP / NAIP / PSMA3 / LPS / MEK / apoptosis / ICAM-1 / BAG-1 / 放射線 / DNA修復 / DNA障害 / ヒストンリン酸化 / ヒストンアセチル化 / モノクローナル抗体 / phosporylation / histone acetylation / DNA repair / DNA damage / radiation / ヒストン脱アセチル化酵素阻害剤 / ヒストンアセチル / non-coding region / microsatellite instability / DNA mismatch repair gene / 遺伝子発現 / non-coding領域 / マイクロサテライト不安定性 / DNAミスマッチ修復遺伝子 / gene analysis / immune complex / dendritic cells / erbB-2 / ERK / キメラ抗体 / 遺伝子解析 / 免疫複合体 / 樹状細胞 / caspase activation / mitochondrial membrame potential / ERK signal / radiosensitivity / radiation-induced apoptosis / Caspase8 / ウイルスベクター / カスペース活性化 / ミトコンドリア膜電位 / ERKシグナル / 放射線誘発アポトーシス / c-erb B-2 / radiation sensitivity / metastasis / radiotherapy / IL-3 / IFN-gamma / Bcl-2 / 癌関連抗原 / 細胞運動能 / 転移 / ヒストンメチル化 / 分子標的治療 / シグナル伝達機構 / ErbB-2 / KAI-1 / DCC / 消火器がん / 食道バレット粘膜 / 予後因子 / ムチン分子 / 膵がん / 早期大腸がん / マトリライシン / 消化器がん / 免疫遺伝子療法 / O-グリカン / アンチセンス抑制 / GalNAcトランスフェラーゼ Less

Investigation of linkage between histone modification and DNA damage after irradiation
- Principal Investigator
  
  HAREYAMA Masato
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Sapporo Medical University
Molecular diagnosis by evaluating histone methylationPrincipal Investigator
- Principal Investigator
  
  ADACHI Masaaki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Sapporo Medical University
低分子化合物を利用した癌に対する強化放射線治療の確立Principal Investigator
- Principal Investigator
  
  安達正晃
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Sapporo Medical University
Development of a new anticancer therapy by reguration of machinery for epigeneticsPrincipal Investigator
- Principal Investigator
  
  ADACHI Masaaki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Sapporo Medical University
Analysis of roles of alterations in non-coding region of genes in carcinogenesis with microsatellite instability
- Principal Investigator
  
  YAMAMOTO Hiroyuki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
Molecular analysis of cross-talk between histone acetylation and radiation sensitivity
- Principal Investigator
  
  HAREYAMA Masato
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Sapporo Medical University
アポトーシス関連分子を利用した癌に対する分子標的療法の確立Principal Investigator
- Principal Investigator
  
  安達正晃
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Sapporo Medical University
Analysis of proapoptotic functions of BH3-only protein BADPrincipal Investigator
- Principal Investigator
  
  ADACHI Masaaki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  細胞死(アポトーシス)
- Research Institution
  Sapporo Medical University
アポトーシス関連分子をターゲットとする新しい癌治療の開発Principal Investigator
- Principal Investigator
  
  安達正晃
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Sapporo Medical University
アポトーシス関連分子をターゲットとする癌治療の開発Principal Investigator
- Principal Investigator
  
  安達正晃
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Sapporo Medical University
抗ErbB-2抗体によるアポトーシス誘導におけるシグナル伝達機構の解析
- Principal Investigator
  
  今井浩三
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  内科学一般
- Research Institution
  Sapporo Medical University
DEVELOPMENT OF NEW CANCER THERAPY USING HISTONE DEACETHYLASE INHIBITORSPrincipal Investigator
- Principal Investigator
  
  ADACHI Masaaki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  SAPPORO MEDICAL UNIVERSITY
消化器がんの進展に関連する分子と治療・予後に関する研究
- Principal Investigator
  
  今井浩三
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Sapporo Medical University
Cancer immunotherapy using dendritic cells and chimeric monoclonal antibody which induce apoptosis
- Principal Investigator
  
  ISHIDA Sadao
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Sapporo Medical University School of Medicin
アポトーシス関連分子をターゲットとする癌転移の制御Principal Investigator
- Principal Investigator
  
  安達正晃
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Sapporo Medical University
Investigation of radiosensitizers with radiation-induced apoptosis
- Principal Investigator
  
  HAREYAMA Masato
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Radiation science
- Research Institution
  SAPPORO MEDICAL UNIVERSITY
チロシンホスファターゼSHP2の制御に基づく免疫強化療法の開発Principal Investigator
- Principal Investigator
  
  安達正晃
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Sapporo Medical University
The new approach of radiotherapy for the prevention of metastasis
- Principal Investigator
  
  HAREYAMA Masato
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  SAPPORO MEDICAL UNIVERSITY, SCHOOL OF MEDICINE
チロシンホスファターゼの分子制御による免疫強化療法の開発Principal Investigator
- Principal Investigator
  
  安達正晃
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Sapporo Medical University
Suppression of tumor metastasis through anti-apoptotic molecules BCL-2/BAG-1Principal Investigator
- Principal Investigator
  
  ADACHI Masaaki
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Sapporo Medical University School of Medicine
GalNAc:ポリペプチド・トランスフェラーゼの発現抑制による癌治療法の開発
- Principal Investigator
  
  日野田裕治
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Sapporo Medical University
REGULATION OF HEMATOPOIETIC CELLS VIA TUMOR SUPPRESSOR GENE WT1Principal Investigator
- Principal Investigator
  
  ADACHI Masaki
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Sapporo Medical University School of Medicine
Significance and functional analysis of protein-tyrosine phosphatases expressed in hematopoietic disorders.Principal Investigator
- Principal Investigator
  
  ADACHI Masaaki
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Sapporo Medical University School of Midicine

All 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book Patent

[Book] 遺伝子治療看護のための最新医学講座第2版24巻(腫瘍の臨床)2008
- Author(s)
  安達正晃
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-19390323
[Book] 基質依存性増殖/アノイキス(Anoikis)改訂培養細胞実験ハンドブック2008
- Author(s)
  安達正晃
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-19590566
[Book] 遺伝子治療看護のための最新医学講座第2版24巻(腫瘍の臨床)2008
- Author(s)
  安達正晃
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-19590566
[Book] 基質依存性増殖/アノイキス(Anoikis)改訂培養細胞実験ハンドブック2008
- Author(s)
  安達正晃
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-19390323
[Book] 改訂培養細胞実験ハンドブック2008
- Author(s)
  安達正晃
- Total Pages
  330
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-19590566
[Journal Article] Oxidative stress impairs the heat stress response and delays unfolded protein recovery.2009
- Author(s)
  Adachi M, Liu Y, Fujii K, Calderwood SK, Nakai A, Imai K, Shinomura Y
- Journal Title
  
  PLoS One 4
  
  Pages: 1-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390323
[Journal Article] Preventing oxidative stress: A new role for XBP12009
- Author(s)
  Liu Y, Adachi M, Zhao S, Hareyama M, Koong AC, Luo D, Rando TA, Imai K and Shinomura Y
- Journal Title
  
  Cell Death Diff (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590566
[Journal Article] Preventing oxidative stress: A new role for XBP1.2009
- Author(s)
  Liu Y, Adachi M, Zhao S, Hareyama M, Koong AC, Luo D, Rando TA, Imai K, Shinomura Y
- Journal Title
  
  Cell Death Diff 16
  
  Pages: 847-857
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390323
[Journal Article] Oxidative stress impairs the heat stress response and delays unfolded protein recovery2009
- Author(s)
  Adachi M
- Journal Title
  
  PLoS One. 4
  
  Pages: 1-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390323
[Journal Article] A novel combination therapy of arsenic trioxide with parthenolide against pancreatic cancer Cells2009
- Author(s)
  Wang W, Adachi M, Zhou J, and Zhu D
- Journal Title
  
  Pancreas (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590566
[Journal Article] A novel combination therapy of arsenic trioxide with parthenolide against pancreatic cancer Cells.2009
- Author(s)
  Wang W, Adachi M, Zhou J, Zhu D
- Journal Title
  
  Pancreas 38
  
  Pages: 114-123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390323
[Journal Article] Nonsteroidal anti-inflammatory drugs and oxidative stress in cancer cells2007
- Author(s)
  Masaaki Adachi
- Journal Title
  
  Histol Histopathol 22
  
  Pages: 437-442
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590273
[Journal Article] Nonsteroidal anti-inflammatory drugs and oxidative stress in cancer cells.2007
- Author(s)
  Adachi M, Sakamoto H, Kawamura R, Wang W, Imai K, Shinomura Y
- Journal Title
  
  Histol Histopathol 22
  
  Pages: 437-442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390323
[Journal Article] Nonsteroidal anti-inflammatory drugs and oxidative stress in cancer cells2007
- Author(s)
  Adachi M, Sakamoto H, Kawamura R, Wang W, Imai K, Shinomura Y
- Journal Title
  
  Histol Histopathol 22
  
  Pages: 437-442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590566
[Journal Article] Nonsteroidal anti-inflammatory drugs and oxidative stress in cancer cells.2007
- Author(s)
  Adachi M.
- Journal Title
  
  Histol Histopathol. 22
  
  Pages: 437-442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390323
[Journal Article] Nonsteroidal anti-inflammatory drugs and oxidative stress in cancer cells.2007
- Author(s)
  Adachi M, Sakamoto H, Kawamura R, Wang W, Imai K, Shinomura Y.
- Journal Title
  
  Histol Histopathol. 22
  
  Pages: 437-442
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590273
[Journal Article] Nonsteroidal anti-inflammatory drugs and oxidative stress in cancer cells2007
- Author(s)
  Masaaki Adachi
- Journal Title
  
  Histol Histopathol 22
  
  Pages: 437-442
- Data Source
  KAKENHI-PROJECT-16390340
[Journal Article] Bmf is a possible mediator in histone deacetylase inhibitors FK228 and CBHA-induced apoptosis.2006
- Author(s)
  Zhang YB, Adachi M, Kawamura R, Imai K.
- Journal Title
  
  Cell Death and Differ. 133
  
  Pages: 129-240
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590273
[Journal Article] Histone deacetylase inhibitors enhance phosphorylation of histone H2AX after ionizing radiation.2006
- Author(s)
  Zhang Y, Adachi M, Zou H, Hareyama M, Imai K, Shinomura Y.
- Journal Title
  
  Int J Radiat Oncol Biol Phys 65
  
  Pages: 859-866
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590273
[Journal Article] Parthenolide-induced apoptosis in multiple myeloma cells involves reactive oxygen species generation and cell sensitivity depends on catalase activity.2006
- Author(s)
  Wang W, Adachi M, Kawamura R, Sakamoto H, Hayashi T, Ishida T, Imai K, Shinomura Y.
- Journal Title
  
  Apoptosis 11
  
  Pages: 2225-2235
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590273
[Journal Article] Bmf contributes to histone deacetylase inhibitor-mediated enhancing effects on apoptosis after ionizing radiation.2006
- Author(s)
  Zhang Y, Adachi M, Kawamura R, Zou HC, Imai K, Hareyama M, Shinomura Y.
- Journal Title
  
  Apoptosis 11
  
  Pages: 1349-1357
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590273
[Journal Article] 2-Methoxyestradiol, an Endogenous Mammalian Metabolite, Radiosensitizes Colon Carcinoma Cells through c-Jun N- Terminal Kinase Activation.2006
- Author(s)
  HuiChao Zou, Masaaki Adachi, Kohzoh Imai, Masato Hareyama, Katsuji Yoshioka, Shiguang Zhao, Yasuhisa Shinomura
- Journal Title
  
  Clin Cancer Res 12
  
  Pages: 6532-6539
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590273
[Journal Article] Nomenclature of dynein light chain-linked BH3-only protein Bim isoforms.2005
- Author(s)
  Adachi M, Zhao X, Imai K.
- Journal Title
  
  Cell Death Differ. 12
  
  Pages: 192-193
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590273
[Journal Article] Adenovirus-mediated gene transfer of caspase-8 sensitizes human adenocarcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand.2005
- Author(s)
  Yasui H, Adachi M, Hamada H, Imai K.
- Journal Title
  
  Int J Oncol. 26
  
  Pages: 537-544
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590273
[Journal Article] Nomenclature of dynein light chain-linked BH3-only protein Bim isoforms2005
- Author(s)
  Adachi M, Zhao X, Imai K.
- Journal Title
  
  Cell Death Differ. 12
  
  Pages: 192-193
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15603004
[Journal Article] Adenovirus-mediated gene transfer of caspase-8 sensitizes human adenocarcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand2005
- Author(s)
  Yasui H, Adachi M, Hamada H, Imai K.
- Journal Title
  
  Int J Oncol. 26
  
  Pages: 537-544
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15603004
[Journal Article] Sulindac Enhances the Proteasome Inhibitor Bortezomib-Mediated Oxidative Stress and Anticancer Activity.2005
- Author(s)
  Minami T, Adachi M, Kawamura R, Zhang YB, Shinomura, Y, Imai K.
- Journal Title
  
  Clin. Cancer Res. 11
  
  Pages: 5248-5256
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590273
[Journal Article] Nomenclature of dynein light chain-linked BH3-only protein Bim isoforms.2005
- Author(s)
  Masaaki Adachi
- Journal Title
  
  Cell Death Differ 12
  
  Pages: 192-193
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590273
[Journal Article] Nomenclature of dynein light chain-linked BH3-only protein Bim isoforms.2005
- Author(s)
  Masaaki Adachi
- Journal Title
  
  Cell Death Differ 12
  
  Pages: 192-193
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15603004
[Journal Article] Frequent epigenetic inactivation of Wnt inhibitory factor-1 in human gastrointestinal cancers.2005
- Author(s)
  Taniguchi, H., Yamamoto, H.(co-first), Hirata, T., Miyamoto, M., Oki, M., Nosho, K., Imsumran, A., Adachi, Y., Endo, T., Imai, K., Shinomura, Y.
- Journal Title
  
  Oncogene 24
  
  Pages: 7946-7952
- NAID
  130004927581
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390213
[Journal Article] Nomenclature of dynein light chain-linked BH3-only protein Bim isoforms.2005
- Author(s)
  Masaaki Adachi
- Journal Title
  
  Cell Death Differ 12
  
  Pages: 192-193
- Data Source
  KAKENHI-PROJECT-17016063
[Journal Article] Synergistic effect of FK228 and CBHA with proteasome inhibitors PSI and PS-341 against gastrointestinal adenocarcinoma cells.2004
- Author(s)
  Masaaki Adachi
- Journal Title
  
  Clin Cancer Res 10
  
  Pages: 3853-3862
- Data Source
  KAKENHI-PROJECT-15603004
[Journal Article] Synergistic effect of histone deacetylase inhibitors FK228 and m-Carboxycinnamic Acid Bis-Hydroxamide with proteasome inhibitors PSI and PS-341 against gastrointestinal adenocarcinoma cell2004
- Author(s)
  Adachi M, Zhang YB, Zhao XD, Minami T, Kawamura R, Hinoda Y, Imai K.
- Journal Title
  
  Clin. Cancer Res. 10
  
  Pages: 3853-3862
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15603004
[Journal Article] Synergistic effect of FK228 and CBHA with proteasome inhibitors PSI and PS- 341 against gastrointestinal adenocarcinoma cells.2004
- Author(s)
  Masaaki Adachi
- Journal Title
  
  Clin Cancer Res 10
  
  Pages: 3853-3862
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15603004
[Journal Article] Histone deacetylase inhibitors FK228,N-4-benzamide and m-carboxycinnamic acid bis-hydroxamide augment radiation-induced cell beth in gastro intestinal adenocarcinoma cells2004
- Author(s)
  Zhang Y, Adachi M, et al.
- Journal Title
  
  Int.J.Cancer 110(2)
  
  Pages: 301-308
- Data Source
  KAKENHI-PROJECT-16390340
[Journal Article] Synergistic effect of histone deacetylase inhibitors FK228 and m-carboxycinnamic acid bis-hydroxamide with proteasome inhibitors PSI and PS-341 against gastrointestinal adenocarcinoma cells.2004
- Author(s)
  Adachi K, Imai K et al.
- Journal Title
  
  Clin Cancer Res. 10
  
  Pages: 3853-3862
- Data Source
  KAKENHI-PROJECT-12218234
[Journal Article] Histone deacetylase inhibitors FK228, N- (2-aminophenyl)-4-[N-(pyridin-3-yl-methoxycarbonyl)aminomethyl] benzamide and M-carboxycinnamic Acid Bis-hydroxamide augment radiation-induced cell death in gastrointestinal adenocarcinoma cells2004
- Author(s)
  Zhang YB, Adachi M, Zhao X., Kawamura R, Imai K.
- Journal Title
  
  Int. J. Cancer 110
  
  Pages: 301-308
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15603004
[Journal Article] Mutation of BAD within the BH3 domain impairs its phosphorylation-mediated regulation.2003
- Author(s)
  Masaaki Adachi
- Journal Title
  
  FEBS Lett 551
  
  Pages: 147-152
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15603004
[Journal Article] Mutation of BAD within the BH3 domain impairs its phosphorylation-mediated regulation2003
- Author(s)
  Adachi M, Zhang YB, Imai K.
- Journal Title
  
  FEBS Letters 551
  
  Pages: 147-152
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15603004
[Journal Article] Histone deacetylase inhibitor CBHA enhances radiation-induced DNA damage and cell death in lung carcinoma A549 cells.
- Author(s)
  Zhang Y, Adachi M, Hareyama M.et al.
- Journal Title
  
  Cancer research (in prints)
- Data Source
  KAKENHI-PROJECT-16390340
[Journal Article] Sulindac Enhances the Proteasome Inhibitor Bortezomib-Mediated Oxidative Stress and Anticancer Activity
- Author(s)
  Minami T, Adachi M, Kawamura R, Zhang YB, Shinomura, Y, Imai K.
- Journal Title
  
  Clin. Cancer Res. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15603004
[Journal Article] Bmf is a possible mediator in histone deacetylase inhibitors FK228 and CBHA-induced apoptosis
- Author(s)
  Zhang YB, Adachi M, Kawamura R, Imai K.
- Journal Title
  
  Cell Death and Differ. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15603004
[Patent] NSAIDを利用した癌治療用組成物2004
- Inventor(s)
  安達正晃
- Industrial Property Rights Holder
  JST
- Industrial Property Number
  2004-063910
- Filing Date
  2004-03-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15603004
[Patent] NSAIDを利用した癌治療用組成物2004
- Inventor(s)
  安達正晃, 今井浩三
- Industrial Property Rights Holder
  科技庁
- Filing Date
  2004-03-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590273
[Patent] HDAC阻害剤による放射線感受性亢進2003
- Inventor(s)
  安達正晃
- Industrial Property Rights Holder
  安達正晃
- Industrial Property Number
  2003-102560
- Filing Date
  2003-04-07
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15603004
[Presentation] 酸化ストレスは、熱ショック後の蛋白質リフォールディング活性を抑制する2009
- Author(s)
  安達正晃劉輝華中井章今井浩三篠村恭久
- Organizer
  日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-19390323
[Presentation] 酸化ストレスは、熱ショック後の蛋白質リフォールディング活性を抑制する2009
- Author(s)
  Adachi M
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-19390323
[Presentation] XBP1の新しい機能2008
- Author(s)
  安達正晃、劉耀華、Koong Albert, 今井浩三、篠村泰久
- Organizer
  第17回日本癌病態治療研究会
- Place of Presentation
  京都
- Year and Date
  2008-06-26
- Data Source
  KAKENHI-PROJECT-19390323
[Presentation]2008
- Author(s)
  安達正晃、劉耀華、Koong Albert, 今井浩三、篠村泰久
- Organizer
  第17回日本癌病態治療研究会
- Place of Presentation
  京都
- Year and Date
  2008-06-26
- Data Source
  KAKENHI-PROJECT-19590566
[Presentation] XBP1の新しい機能 : 酸化ストレス応答への関与2008
- Author(s)
  安達正晃、劉耀華、趙世光、Koong Albert, Rando Thomas, Dan Ruo, 今井浩三、篠村泰久
- Organizer
  日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19590566
[Presentation] Preventing oxidative stress : A new role for XBP1 and its candidate as a molecular target for cancer2008
- Author(s)
  Adachi M, Liu Y, Zhao S, Hareyama M, Koong A, Imai K and Shinomura Y
- Organizer
  The 6^<th> International Symposium on cancer research and therapy
- Place of Presentation
  Tokyo
- Year and Date
  2008-11-22
- Data Source
  KAKENHI-PROJECT-19590566
[Presentation] x bp1の新しい機能:酸化ストレス応答への関与2008
- Author(s)
  安達正晃、劉耀華、趙世光、Koong Albert, Rando Thomas, Dan Ruo, 今井浩三, 篠村泰久
- Organizer
  日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19390323
[Presentation] Preventing oxidative stress: A new role for XBP1 and its candidate as a molecular target for cancer.2008
- Author(s)
  Adachi M, Liu Y, Zhao S, Hareyama M, Koong A, Imai K, Shinomura Y
- Organizer
  he 6th International Symposium on cancer research and therapy
- Place of Presentation
  Tokyo
- Year and Date
  2008-11-22
- Data Source
  KAKENHI-PROJECT-19390323
[Presentation] XBP1の新しい機能 : 酸化ストレス応答への関与2008
- Author(s)
  安達正晃
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19590566
[Presentation] 内在性ホルモンを利用した新たな放射線感受性亢進療法の開発2007
- Author(s)
  安達正晃、今井浩三、晴山雅人、篠村恭久
- Organizer
  日本癌病態治療研究会
- Place of Presentation
  東京
- Year and Date
  2007-06-28
- Data Source
  KAKENHI-PROJECT-19390323
[Presentation] IL-2シグナルと小胞体ストレスシグナル2007
- Author(s)
  安達正晃, 劉耀華、今井浩三、篠村泰久
- Organizer
  日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19390323
[Presentation] IL-2シグナルと小胞体ストレスシグナル2007
- Author(s)
  安達正晃, 劉耀華、今井浩三、篠村泰久
- Organizer
  日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19590566
[Presentation] 内在性ホルモンを利用した新たな放射線感受性亢進療法の開発2007
- Author(s)
  安達正晃、今井浩三、晴山雅人、篠村恭久
- Organizer
  第16回日本癌病態治療研究会
- Place of Presentation
  東京
- Year and Date
  2007-06-28
- Data Source
  KAKENHI-PROJECT-19590566

1. IMAI Imai (60117603)

# of Collaborated Projects: 12 results

# of Collaborated Products: 24 results
2. SAKATA Ko-ichi (10235153)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. HAREYAMA Masato (10173098)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
4. SASAKI Shigeru (10305229)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. HAYASHI Toshiaki (30381271)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. 日野田裕治 (10165128)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 牧口祐介 (40274922)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 遠藤高夫 (40191928)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. YASUI Hiroshi (40448593)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ISHIDA Sadao (20305220)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. YAMAMOTO Hiroyuki (40332910)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. KOITO Kazumitsu (90153460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 伊東文生 (90223180)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 賀佐伸省 (10142712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 有村佳昭 (80305218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 森田和夫 (20045347)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

ADACHI Masaaki 安達 正晃

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Molecular diagnosis by evaluating histone methylationPrincipal Investigator

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低分子化合物を利用した癌に対する強化放射線治療の確立Principal Investigator

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Development of a new anticancer therapy by reguration of machinery for epigeneticsPrincipal Investigator

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アポトーシス関連分子を利用した癌に対する分子標的療法の確立Principal Investigator

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Analysis of proapoptotic functions of BH3-only protein BADPrincipal Investigator

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アポトーシス関連分子をターゲットとする新しい癌治療の開発Principal Investigator

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アポトーシス関連分子をターゲットとする癌治療の開発Principal Investigator

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DEVELOPMENT OF NEW CANCER THERAPY USING HISTONE DEACETHYLASE INHIBITORSPrincipal Investigator

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ADACHI Masaaki 安達正晃