HATAKEYAMA Noboru 畠山登

Researcher Number	70251907
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2019 – 2020: 愛知医科大学, 医学部, 教授 2011 – 2014: 愛知医科大学, 医学部, 教授 2010: 冨山大学, 大学病院, 准教授 2010: 富山大学, 附属病院, 准教授 2010: 富山大学, 附属病院手術部, 副部長,准教授 … More
Review Section/Research Field	Principal Investigator Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies / Basic Section 55050:Anesthesiology-related Except Principal Investigator Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies / Laboratory medicine
Keywords	Principal Investigator カリウムチャネル / 活動電位 / 不整脈 / 敗血症 / 全身麻酔薬 / 吸入麻酔薬 / 静脈麻酔薬 / カルシウムチャネル / 頻脈性不整脈 / 心房筋 … More Except Principal Investigator vascular smooth muscle / 血管平滑筋 / 膜電位 / イソフルラン / セボフルラン / プロポフォール / WKYラット / SHRラット / K^+チャネル / hypertension / transmembrane potential / isoflurane / sevoflurane / propofol / potassium channel / EDHF / 転写因子 / NF-κB / 1分子蛍光相関法 / 全身炎症反応症候群 / 救急医療 / 1分子蛍光法 / 炎症性サイトカイン / 迅速検査 / 全身性炎症反応候群 / 菌血症 / 全身性炎症反応症候群 / 一分子蛍光法 / 核蛋白抽出法 / neuropathic pain / enriched environment / neurogenesis / central nervous system / 豊かな環境 / エピジェネティクス修飾 / 神経新生 / 海馬 / セルソーティング / マイクログリア / エピジェネティクス / ヒストン / メチル化 / 神経障害性疼痛 / ファンクショナルMRI / ダイノルフィンA / オピオイド受容体 / 麻酔学 / ヒト血管 / 平滑筋 / 高血糖 / NADPHオキシダーゼ / アクチン / ATP感受性カリウムチャネル / 揮発性麻酔薬 / 脳 / 驚愕反応 / 薬理学 / 全身麻酔薬 / 膜流動化 / 単離心筋細胞 / カルシウムチャネル / 全細胞膜電位固定 / 膜電流固定 / カルシウムチャネル / 膜容量 / 細胞膜 / 吸入麻酔薬 / 静脈麻酔薬 / イオンチャネル / 心筋単離細胞 / パッチクランプ法 / GENERAL ANESTHETICS / MEMBRANE FLUIDITY / CARDIAC MYOCYTE / CALCIUM CHANNEL / WHORE-CELL VOLTAGE CLAMP / CURRENT CLAMP / normotension / anesthetics / membrane potential / peripheral vascular tone / splanchnic resistance / splanchnic capacitance / WKY rat / SHR rat / ポタシウムチャネル / 高血圧 / cAMP / SQ22536 / Rp-cAMPS / L-NAME / NO-cGMP系 / EDHA / アセチルコリン Less

敗血症性心筋症の病態生理学的解明およびカテコラミン類修飾作用の研究Principal Investigator
- Principal Investigator
  
  畠山登
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Aichi Medical University
Effect of micro-RNA on tachyarrhythmia in septic condition.Principal Investigator
- Principal Investigator
  
  HATAKEYAMA Noboru
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Aichi Medical University
Role of astrocyte metabolism in the constitution of long-term memory and the molecular pharmacological effect of anesthetics
- Principal Investigator
  
  KINOSHITA Hiroyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Aichi Medical University
Therapeutic strategy for the chronic pain through the neurogenesis of the central nervous system in enriched environment
- Principal Investigator
  
  YAMAZAKI Mitsuaki
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Toyama
Mechanisms of oxidative stress in the human arteries from patients with metabolic syndrome and the treatment using a gene therapy
- Principal Investigator
  
  IRANAMI Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Wakayama Medical University
Effects of septic condition on pacemaking cell.-Anti-arrhythmic strategy by gene-based treatments-Principal Investigator
- Principal Investigator
  
  HATAKEYAMA Noboru
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Aichi Medical University
  University of Toyama
Development of the hypersensitive and rapid detection method for NF-κB activation using by Fluorescence Correlation Spectroscopy and its application to the emergency medicine
- Principal Investigator
  
  KITAJIMA Isao
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  University of Toyama
Pathologic analysis of septic supraventricular tachyarrhythmia-clarification of pathogenesis and establishment of treatment-Principal Investigator
- Principal Investigator
  
  HATAKEYAMA Noboru
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Toyama
Research on the mechanism of arrhythmia induced by general anesthetic on atrial pacemakerPrincipal Investigator
- Principal Investigator
  
  HATAKEYAMA Noboru
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Toyama
  Toyama Medical and Pharmaceutical University
イオンチャネルと細胞内情報伝達系に及ぼす全身麻酔薬の影響Principal Investigator
- Principal Investigator
  
  畠山登
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Toyama Medical and Pharmaceutical University
The effects of anesthetics on transmembrane potential, transmembrane currents and EDHF in resistance and capacitance blood vessels (microcirculation)
- Principal Investigator
  
  YAMAZAKI Mitsuaki
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
虚血心筋に対する全身麻酔薬の細胞保護作用についての研究Principal Investigator
- Principal Investigator
  
  畠山登
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Toyama Medical and Pharmaceutical University
Mechanisms of anesthetics on in situ normotensive vs hypertensive rat mesenteric vascular smooth muscle transmembrane potentials
- Principal Investigator
  
  YAMAZAKI Mitsuaki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Toyama Medical and Pharmaceutical University
IS CHANNEL BLOCKING EFFECT CAUSED BY GENERAL ANESTHETICS PARTICIPATE IN MEMBRANE FLUIDATION?
- Principal Investigator
  
  ITO Yusuke
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY

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All Journal Article Presentation Book

[Book] カテコラミンの使い方Pros & Cons.救急・ERノート22011
- Author(s)
  畠山登
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21592001
[Book] 吸入麻酔と心血管系.「吸入麻酔薬理から使用法まで」2003
- Author(s)
  山崎光章, 畠山登, 広田弘毅
- Total Pages
  22
- Publisher
  真興交易医書出版部
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591619
[Journal Article] Mechanisms of Inflammatory Response and Organ Dysfunction: Organ-Protective Strategy by Anesthetics.2014
- Author(s)
  Hatakeyama N, Matsuda N
- Journal Title
  
  Curr Pharm Des
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592362
[Journal Article] Alert cell strategy: mechanisms of inflammatory response and organ protection.2014
- Author(s)
  Hatakeyama N, Matsuda N
- Journal Title
  
  Curr Pharm Des.
  
  Volume: 20 Pages: 5766-5778
- DOI
  10.2174/138161282036140912122809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592362
[Journal Article] Role of ion channels in sepsis-induced atrial tachyarrhythmias in guinea pigs2012
- Author(s)
  Aoki Y, Hatakeyama N, Yamamoto S, Kinoshita H, Matsuda N, Hattori Y, Yamazaki M
- Journal Title
  
  Br J Pharmacol
  
  Volume: 166 Pages: 390-400
- DOI
  10.1111/j.1476-5381.2011.01769.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592001, KAKENHI-PUBLICLY-23122506
[Journal Article] le of ion channels in sepsis-induced atrial tachyarrhythmia in guinea pi2012
- Author(s)
  uta Aoki, Noboru Hatakeyama, et al
- Journal Title
  
  British Journal of Pharmacology
  
  Volume: 166 Pages: 390-400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592001
[Journal Article] Effects of gabapentin on brain hyperactivity related to pain and sleep disturbance under a neuropathic pain-like state using fMRI and brain wave analysis2011
- Author(s)
  Takemura Y, Yamashita A, Horiuchi H, Furuya M, Yanase M, Niikura K, Imai S, Hatakeyama N, Kinoshita H, Tsukiyama Y, Senba E, Matoba M, Kuzumaki N, Yamazaki M, Suzuki T, Narita M
- Journal Title
  
  Synapse
  
  Volume: 65 Pages: 668-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390431
[Journal Article] Effects of gabapentin on brain hyperactivity related to pain and sleep disturbance under a neuropathic pain-like state using fMRI and brain wave analysis.2011
- Author(s)
  Takemura Y, Yamashita A, Horiuchi H, Furuya M, Yanase M, Niikura K, Imai S, Hatakeyama N, Kinoshita H, Tsukiyama Y, Senba E, Matoba M, Kuzumaki N, Yamazaki M, Suzuki T, Narita M.
- Journal Title
  
  Synapse
  
  Volume: 65 Pages: 668-676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390431
[Journal Article] The modulation of vascular ATP-sensitive K^+channel function via phosphatidylinosito 3-kinase-Akt pathway activated by phenylephrine2010
- Author(s)
  Haba M, Hatakeyama N, Kinoshita H, Teramae H, Azma T, Hatano Y, Matsuda N
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 334 Pages: 673-678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591985
[Journal Article] 全身性炎症反応症候群(SIRS)と頻脈性不整脈,その治療戦略2010
- Author(s)
  畠山登
- Journal Title
  
  日臨麻会誌
  
  Volume: 30 Pages: 765-770
- NAID
  10026629715
- Data Source
  KAKENHI-PROJECT-21592001
[Journal Article] 周術期不整脈の管理と治療全身性炎症反応症候群(SIRS)と頻脈性不整脈、その治療戦略2010
- Author(s)
  畠山登, 青木優太, 木下浩之, 寺前洋生, 松田直之, 山崎光章
- Journal Title
  
  日本臨床麻酔学会誌
  
  Volume: 30巻5号 Pages: 765-770
- Data Source
  KAKENHI-PROJECT-21592001
[Journal Article] 敗血症性ショックにおけるアポトーシスの治療2009
- Author(s)
  松田直之, 山本誠士, 寺前洋生, 高野健一, 別府賢, 山崎弘美, 横尾宏毅, 畠山登, 小池薫, 服部裕一
- Journal Title
  
  日本薬理学雑誌
  
  Volume: 134巻4号 Pages: 198-201
- NAID
  10025741693
- Data Source
  KAKENHI-PROJECT-21592001
[Journal Article] 敗血症性ショックにおけるアポトーシスの治療2009
- Author(s)
  松田直之, 山本誠士, 寺前洋生, 高野健一, 別府賢, 山崎弘美, 横尾宏毅, 畠山登, 小池薫, 服部裕一
- Journal Title
  
  日本薬理学雑誌 134
  
  Pages: 198-201
- NAID
  10025741693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592001
[Journal Article] Pharmacological significance of the blocking action of the intravenous general an esthetic propofol on the slow component of cardiac delayed rectifier K+ current.2009
- Author(s)
  Hatakeyama N, Sakuraya F, Matsud a N, Kimura J, Kinoshita H, Kemmotsu O, Yamazaki M, Hattori Y.
- Journal Title
  
  J Pharmacol Sci 110
  
  Pages: 334-343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592001
[Journal Article] Pharmacological significance of the blocking action of the intravenous general anesthetic propofol on the slow component of cardiac delayed rectifier K+current2009
- Author(s)
  Hatakeyama N, Sakuraya F, Matsuda N, Kimura J, Kinoshita H, Kemmotsu O, Yamazaki M, Hattori Y
- Journal Title
  
  J Pharmacol Sci. 2009 Jul
  
  Volume: 110(3) Pages: 334-43
- NAID
  10025737753
- Data Source
  KAKENHI-PROJECT-21592001
[Journal Article] Pharmacological significance of the blocking action of the intravenous general anesthetic propofol on the slow component of cardiac delayed rectifier K+ current2009
- Author(s)
  Hakakeyama N, Sakuraya F, Matsuda N, Kimura J, Kinoshita H, Kemmotsu O, Yamazaki M, Hattiri Y
- Journal Title
  
  J.Pharmacol Sci 110(3)
  
  Pages: 334-343
- NAID
  10025737753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590559
[Journal Article] The beneficial effect of propofol on arterial adenosine triphosphate-sensitive K^+channel function impaired by thromboxane2009
- Author(s)
  Haba M, Kinoshita H, Matsuda N, Azma T, Hama-Tomioka K, Hatakeyama N, Yamazaki M, Hatano Y
- Journal Title
  
  Anesthesiology
  
  Volume: 111 Pages: 279-286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591985
[Journal Article] severity of obstructive speep apnea syndrome may affect postoperative hypoxemia in morbidly obese patients.2009
- Author(s)
  Kinoshita H, Hatakeyama N, Minonishi T, Hatano Y
- Journal Title
  
  Aneth Analg 108
  
  Pages: 1044-1044
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590559
[Journal Article] Pharmacological significance of the blocking action of the intravenous general anesthetic propofol on the slow component of cardiac delayed rectifier K+ current.2009
- Author(s)
  Hatakeyama N, Sakuraya F, Matsuda N, Kimura J, Kinoshita H, Kemmotsu O, Yamazaki M, Hattori Y
- Journal Title
  
  J.Pharmacol Sci. 110
  
  Pages: 334-343
- NAID
  10025737753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590559
[Journal Article] Role of phosphatidylinositol 3-kinase and NADHP oxidase in ATP-sensitive K+ channel function impaired by high glucose in the human artery.2008
- Author(s)
  Kinoshita H, Matsuda N, Hatakeyama N, Azma T, Kuroda Y, Tange K, Hatano Y
- Journal Title
  
  Hypertension 52
  
  Pages: 507-513
- Data Source
  KAKENHI-PROJECT-20590559
[Journal Article] Modulation of glucocorticoid receptor expression, inflammation, and cell apoptosis2008
- Author(s)
  Kamiyama K, Matsuda N, Yamamoto S, Takano KI, Takano Y, Yamazaki H, Kageyama SI, Yokoo H, Nagata T, Hatakeyama N, Tsukada K, Hattori Y.
- Journal Title
  
  in septic guinea-pig lungs using methylprednisolone. Am J Physiol Lung Cell Mol Physiol
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591782
[Journal Article] Roles of phosphatidylinositol 3-kinase-Akt and NADPH oxidase in adenosine 5'-triphosphate-sensitive K+ channel function impaired by high glucose in the human artery2008
- Author(s)
  Kinoshita H, Matsuda N, Kaba H, Hatakeyama N, Azma T, Nakahata K, Kuroda Y, Tange K, Iranami H, Hatano Y.
- Journal Title
  
  Hypertension 52(3)
  
  Pages: 507-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591782
[Journal Article] Cholinesterase inhibitor donepezil dilates cerebral parenchymal arterioles via the activation of neuronal nitric oxide synthase2008
- Author(s)
  Nakahata K, Kinoshita H, Hama-Tomioka K, Ishida Y, Matsuda N, Hatakeyama N, Haba M, Kondo T, Hatano Y.
- Journal Title
  
  Anesthesiology 109(1)
  
  Pages: 124-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591782
[Journal Article] Modulation of glucocorticoid receptor expression, inflammation and cell apoptosis in septic guinea-pig lung using methylprednisolone.2008
- Author(s)
  Kamiyama K, Matsuda N, Yamamoto S, Takano K, Takano Y, Yamazaki H, Kageyama SI, Kokoo H, Nagata H, Hatakeyama N, Tsukada K, Hattori Y
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol. 259
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590559
[Journal Article] 敗血症性ショックにおける血管内皮細胞の機能異常2008
- Author(s)
  松田直之, 山本誠士, 畠山登, 服部裕一
- Journal Title
  
  日本薬理学雑誌 131(2)
  
  Pages: 96-100
- NAID
  10024186629
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591782
[Journal Article] Modulation of glucocirticoid receptor expression, inflammation, and cell apoptosis in septic guinea pig lungs using methylprednisolone.2008
- Author(s)
  Kamiya K, Matsuda N, Yamamoto S, Takano K, Yamazaki H, Hakakeyama N
- Journal Title
  
  Am I Physiology Lung Cell Mol Physiol 295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590559
[Journal Article] Cholinesterase inhibitor donepezil dilates cerebral parenchymal arterioles via the activation of neuronal nitric oxide synthase.2008
- Author(s)
  Nakahata K, Kinoshita H, Ishida Y, Matsuda N, Hatakeyama N, Kondo T, Hatano Y
- Journal Title
  
  Anethesiology 109
  
  Pages: 124-129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590559
[Journal Article] Effects of thiopental on Ca2+ currents and intracellular Ca2+ transient in single atrial cells from guinea pig2007
- Author(s)
  Kimura M, Shibukawa Y, Momose Y, Sugaya M, Yamamura S, Suzuki T, Hatakeyama N, Yamazaki M.
- Journal Title
  
  Pharmacology 80(1)
  
  Pages: 33-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591782
[Journal Article] Surviving Sepsis Campaign guidlines におけるrelative adrenal insufficiency の対策2007
- Author(s)
  松田直之, 山本誠士, 神山公希, 畠山登, 渋谷伸子, 服部裕一, 山崎光章
- Journal Title
  
  救急医学 31
  
  Pages: 1362-1370
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591782
[Journal Article] Siencing of caspase-8 and caspase-3 by RNA interference prevents vascular endothelial cell injury in mice with endotoxic shock2007
- Author(s)
  Matsuda N, Takano Y, Kageyama S, Hatakeyama N, Shakunaga K, Kitajima I, Yamazaki M, Hattori Y.
- Journal Title
  
  Cardiovasc Res 76
  
  Pages: 132-140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591782
[Journal Article] Silencing of caspase-8 and caspase-3 by RNA interference prevents vascular endothelial cell injury in mice with endotoxic shock2007
- Author(s)
  Matsuda N, Takano Y, Kageyama S, Hatakeyama N, Shakunaga K, Kitajima I, Yamazaki M, Hattori Y.
- Journal Title
  
  1;76(1)
  
  Pages: 132-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591782
[Journal Article] The Effects of Sevoflurane and Propofol on QT Interval and Heterologously Expressed Human Ether-A-Go-Go Related Gene Currents in Xenopus Oocytes2006
- Author(s)
  M.Yamada, N.Hatakeyama, A.Malykhina, M.Yamazaki, Y.Momose, H.Akbarali
- Journal Title
  
  Anesthesia & Analgesia 102
  
  Pages: 98-103
- Data Source
  KAKENHI-PROJECT-15591619
[Journal Article] The Effects of Sevoflurane and Propofol on QT Interval and Heterologously Expressed Human Ether-A-Go-Go Related Gene Currents in Xenopus Qocytes2006
- Author(s)
  M.Yamada, N.Hatakeyama, A.Malykhina, M.Yamazaki Y.Momose, H.Akbarali
- Journal Title
  
  Anesth Analg 102
  
  Pages: 98-103
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591619
[Journal Article] The Effects of Sevoflurane and Propofol on QT Interval and Heterologously Expressed Human Ether-A-Go-Go Related Gene Currents in Xenopus Oocytes2006
- Author(s)
  Y.Yamada, N.Hatakeyama, A Malykhina, M.Yamazaki, Y.Momose, H.Akbarali
- Journal Title
  
  Anesthesia & Analgesia 102
  
  Pages: 98-103
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591619
[Journal Article] Effect of general anesthetics on membrane capacitance in guinea-pig single cardiac myocyte2004
- Author(s)
  Hatakeyama N, Shibuya N, Yamada M, Hirota K, Yamazaki M, Yamamura S, Momose Y
- Journal Title
  
  Oyo Yakuri / Pharmacometrics 66
  
  Pages: 7-10
- NAID
  10013290577
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591619
[Journal Article] Effect of general anesthetics on membrane capacitance in guinea-pig single cardiac myocyte2004
- Author(s)
  Hatakeyama N, Shibuya N, Yamada M, Hirota K, Yamazaki M, Yamamura S, Momose Y
- Journal Title
  
  Oyo Yakuri/Pharmacometrics 66
  
  Pages: 7-10
- NAID
  10013290577
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591619
[Journal Article] Effect of general anesthetics on membrane capacitance in guinea-pig single cardiac myocyte2004
- Author(s)
  Hatakeyama N, Shibuya N, Yamada M, Hirota K, Yamazaki M, Yamamura, Momose Y, Sugaya M
- Journal Title
  
  Pharmacometrics 66
  
  Pages: 7-10
- NAID
  10013290577
- Data Source
  KAKENHI-PROJECT-15591619
[Journal Article] セボフルランによるQT間隔延長機序についての電気生理学的検討2003
- Author(s)
  山田正名, 畠山登, 澁谷伸子, 百瀬弥寿徳, 山崎光章
- Journal Title
  
  麻酔 52
  
  Pages: 482-488
- NAID
  40005826811
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591619
[Presentation] いまさら聞けない循環作動薬の作用と使い方2020
- Author(s)
  畠山　登
- Organizer
  第47回日本集中治療医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K09338
[Presentation] 心血管系におけるmicroRNAの役割と今後の展望2012
- Author(s)
  畠山　登
- Organizer
  日本心臓血管麻酔学会第17回学術大会
- Place of Presentation
  仙台
- Invited
- Data Source
  KAKENHI-PROJECT-24592362
[Presentation] MODULATION OF EXPRESSION AND FUNCTION OF ION CHANNELS IN ATRIAL MYOCYTE FROM SEPTIC GUINEA PIG2012
- Author(s)
  N.Hatakeyama
- Organizer
  ESICM LIVES 2012 25th Annual Congress
- Place of Presentation
  Lisbon
- Data Source
  KAKENHI-PROJECT-24592362
[Presentation] Modulation on Expression and Function of Calcium and Potassium Channels in Septic Guinea Pig Atrium2011
- Author(s)
  Hatakeyama N.
- Organizer
  Society of critical Care Medicine 40th Critical Care Congress
- Place of Presentation
  San Diego, U. S. A.
- Data Source
  KAKENHI-PROJECT-21592001
[Presentation] Modulation of Potassium Channel Plays a Role for Septic Tachyarrhythmia2011
- Author(s)
  Hatakeyama N.
- Organizer
  2011 Annual Meeting of the American Society Anesthesiologists
- Place of Presentation
  Chicago, U. S. A.
- Data Source
  KAKENHI-PROJECT-21592001
[Presentation] Modulation of Potassium Channel Plays a Role for Septic Tachyarrhythmia2011
- Author(s)
  Noboru Hatakeyama
- Organizer
  2011 ASA Annual Meeting
- Place of Presentation
  Chicago, USA
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-21592001
[Presentation] Modulation on Expression and Function of Calcium and Potassium Channels in Septic Guinea Pig Atrium.2011
- Author(s)
  畠山登
- Organizer
  SCCM 40^<th> Critical Care Congress
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-21592001
[Presentation] イソフルランは高濃度ブドウ糖による酸化ストレスからヒトATP感受性カリウムチャネル機能を保護する2011
- Author(s)
  木下浩之、松田直之、東俊晴、畠山登、伊良波浩、山崎光章
- Organizer
  日本麻酔科学会第58回学術集会
- Place of Presentation
  兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-21591985
[Presentation] Tachyarrhythmia in sepsis is attributable to both the inhibition of calcium channel expression and nitrotyrosilation of calcium channel2010
- Author(s)
  Hatakeyama N.
- Organizer
  Society of critical Care Medicine 39th Critical Care Congress
- Place of Presentation
  Miami Beach, U. S. A.
- Data Source
  KAKENHI-PROJECT-21592001
[Presentation] 高濃度ブドウ糖で抑制されたヒト大網動脈ATP感受性カリウムチャネル機能に及ぼす細胞骨格制御の効果2010
- Author(s)
  木下浩之、松田直之、東俊晴、畠山登、中畑克俊、畑埜義雄
- Organizer
  日本麻酔科学会第57回学術集会
- Place of Presentation
  福岡県福岡市
- Data Source
  KAKENHI-PROJECT-21591985
[Presentation] 敗血症時の頻脈性不整脈発生機序に対するnitrotyrosylationの影響2010
- Author(s)
  畠山登
- Organizer
  第31回循環制御医学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21592001
[Presentation] 敗血症モルモットにおける心房筋カルシウムチャネル変化の検討2010
- Author(s)
  畠山登
- Organizer
  第31回循環制御医学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21592001
[Presentation] 酸化ストレスによるモルモット心室筋活動電位変化とプロポフォールによる影響についての検討2010
- Author(s)
  畠山登
- Organizer
  日本麻酔科学会第57回学術集会
- Place of Presentation
  福岡
- Year and Date
  2010-06-04
- Data Source
  KAKENHI-PROJECT-21592001
[Presentation] Effect of Hydrogen Peroxide on Action Potential and the Protection by Propofol in Cardiac Myocytes2010
- Author(s)
  Hatakeyama N
- Organizer
  2010 Annual Meeting of the American Society Anesthesiologists
- Place of Presentation
  San Diego, U. S. A.
- Data Source
  KAKENHI-PROJECT-21592001
[Presentation] Isoflurane protects human ATP-sensitive K^+channels from oxidative stress induced by high glucose2010
- Author(s)
  Kinoshita H, Matsuda N, Hatakeyama N, Iranami H, Hatano Y
- Organizer
  2010 Annual Meeting of American Society of Anesthesiologist
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-21591985
[Presentation] Sepsis-Induced Modulation of Ion Channels and the Role of Protein Nitrosylation in Atrial Myocytes.2010
- Author(s)
  畠山登
- Organizer
  2010 ASA Annual Meeting
- Place of Presentation
  San Diego, USA
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-21592001
[Presentation] 全身性炎症反応症候群・敗血症と急性腎障害2010
- Author(s)
  畠山登
- Organizer
  日本心臓血管麻酔学会第15回学術大会
- Place of Presentation
  東京
- Year and Date
  2010-10-10
- Data Source
  KAKENHI-PROJECT-21592001
[Presentation] Isoflurane protects human ATP-sensitive K^+ channels from oxid ative stress induced by high glucose2010
- Author(s)
  Kinoshita H, Matsuda N, Hatakeyama N, Iranami H, Hatano Y
- Organizer
  2010 Annual Meeting of American Society of Anesthesiologist
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-21591985
[Presentation] 敗血症モルモット心房筋カルシウムチャネル発現および機能の変化2010
- Author(s)
  畠山登
- Organizer
  日本麻酔科学会第57回学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-21592001
[Presentation] The Role of Cytoskeleton in Vascular ATP-Sensitive K^+Channel Function Modified by High Glucose2009
- Author(s)
  Kinoshita H, Hatakeyama N, Hatano Y
- Organizer
  2009 Annual Meeting of American Society of Anesthesiologist
- Place of Presentation
  New Orleans, LA
- Data Source
  KAKENHI-PROJECT-21591985
[Presentation] Involvement of Ca2+ and Na+ Channels in the Mechanism of Tachyarrhythmia in Septic Guinea Pig Atrialum2009
- Author(s)
  Hatakeyama N, Aoki Y, Yamazaki M, Matsuda N, Yamamoto S, Hattori Y
- Organizer
  Society of critical Care Medicine 38th Critical Care Congress
- Place of Presentation
  Nashville, USA
- Data Source
  KAKENHI-PROJECT-19591782
[Presentation] 敗血症時の頻脈性不整脈における心房筋イオンチャネル発現と機能の変化2009
- Author(s)
  畠山登
- Organizer
  社団法人日本麻酔科学会第56回学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21592001
[Presentation] 敗血症時の頻脈性不整脈発生機序に対するnitrotyrosylationの影響2009
- Author(s)
  畠山登
- Organizer
  第30回日本循環制御医学会総会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-21592001
[Presentation] 敗血症時の頻脈性不整脈における心房筋イオンチャネル発現と機能の変化2009
- Author(s)
  畠山登
- Organizer
  日本麻酔科学会第56回学術大会
- Place of Presentation
  神戸
- Year and Date
  2009-08-18
- Data Source
  KAKENHI-PROJECT-21592001
[Presentation] 全身性炎症反応症候群(SIRS)と頻脈性不整脈,その治療戦略2009
- Author(s)
  畠山登
- Organizer
  日本臨床麻酔学会第29回大会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-21592001
[Presentation] Involvement of Ca2^+ and Na^+ channels in the mechanism of tachyarrhythmia in septic guinea pig atrium2009
- Author(s)
  Hatakeyama N, et al
- Organizer
  Society of Critical Care Medicine's 38^<th> Critical Care Congress
- Place of Presentation
  Nashville TN, USA
- Data Source
  KAKENHI-PROJECT-19591782
[Presentation] Gene silencing of FADD with small interfering RNA improves septic survival by prevention of apoptosis in main organs2008
- Author(s)
  Matsuda N, Koike K, Kageyama SI, Yamamoto S, Hatakeyama N, Takano Y, Hattori Y
- Organizer
  Society of critical Care Medicine 37th Critical Care Congress 2008
- Place of Presentation
  Honolulu
- Data Source
  KAKENHI-PROJECT-19591782
[Presentation] 心房筋炎症におけるL型Ca2+チャネル蛋白の発現抑制機構2008
- Author(s)
  松田直之, 丸山彩子, 内御堂亮, 釈永清志, 畠山登, 山崎光章
- Organizer
  日本麻酔科学会第55回学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19591782
[Presentation] Mechanism of Tachyarrhythmia in Septic Guinea Pig Myocyte2008
- Author(s)
  Hatakeyama N, Matsuda N, Aoki Y, Hattori Yamazaki M.
- Organizer
  37th critical Care Congress, Society of Critical Care Medicine
- Place of Presentation
  Honolulu, HI, U.S.A.
- Data Source
  KAKENHI-PROJECT-19591782
[Presentation] Mechanism of tachyarrhythmia in septic guinea pig atrial myocyte2008
- Author(s)
  Hatakeyama N, Matsuda N, Aoki Y, Hattori Y, Yamazaki M.
- Organizer
  Society of critical Care Medicine 37th Critical Care Congress
- Place of Presentation
  Honolulu
- Data Source
  KAKENHI-PROJECT-19591782
[Presentation] Involvement of Na^+ channel in the mechanism of tachyarrhythmia in septic guinea pig atrial myocyte2008
- Author(s)
  Hatakeyama N, et al
- Organizer
  2008 Annual Meeting of American Society of Anesthesiologists
- Place of Presentation
  Orlando FL, USA
- Data Source
  KAKENHI-PROJECT-19591782
[Presentation] Involvement of Na + channel in the mechanism of tachyarrhythmia in septic guinea pig atrial myocyte2008
- Author(s)
  Hatakeyama N, Matsuda N, Aoki Y, Yamada M, Yamazaki M.
- Organizer
  2008 Annual Meeting of American Society of Anesthesiologysts
- Place of Presentation
  Orlando
- Data Source
  KAKENHI-PROJECT-19591782
[Presentation] 敗血症モルモット単離心房筋細胞におけるナトリウム・カルシウムチャネル電流および膜電位変化についての検討2008
- Author(s)
  畠山登, 松田直之, 青木優太, 渋谷伸子, 百瀬弥寿徳, 山崎光章
- Organizer
  日本麻酔科学会第55回学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19591782
[Presentation] 敗血症モルモット単離心房筋細胞におけるイオンチャネル電流についての検討2007
- Author(s)
  畠山登, 松田直, 山崎光章, 服部裕一
- Organizer
  第80回日本薬理学会年会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19591782
[Presentation] 敗血症モルモット単離心房筋細胞におけるカルシウムチャンネル電流の解析2007
- Author(s)
  畠山登, 松田直之, 青木優太, 山崎光章
- Organizer
  第28回日本循環制御医学会総会
- Place of Presentation
  和歌山
- Data Source
  KAKENHI-PROJECT-19591782
[Presentation] モルモット急性肺傷害におけるグルココルチコイド受容体の発現敗血症性肺傷害に対する大量ステロイド療法の弊害2007
- Author(s)
  神山公希, 松田直之, 山本誠士, 影山俊一郎, 高野健一, 山崎弘美, 長田拓哉, 畠山登, 塚田一博, 服部裕一
- Organizer
  第58回日本薬理学会北部会総会
- Place of Presentation
  札幌
- Year and Date
  2007-09-29
- Data Source
  KAKENHI-PROJECT-19591782
[Presentation] 敗血症モルモット単離心房筋細胞チャネル電流についての検討2007
- Author(s)
  畠山登, 松田直之, 青木優太, 釈永清志, 山崎光章
- Organizer
  (社)日本麻酔科学会東海・北陸支部第4回学術集会
- Place of Presentation
  名古屋
- Year and Date
  2007-02-17
- Data Source
  KAKENHI-PROJECT-19591782
[Presentation] 敗血症病態におけるヒスタミンH4受容体を介した主要臓器の抗炎症作用2007
- Author(s)
  松田直之, 影山俊一郎, 畠山登, 釈永清志, 山崎光章
- Organizer
  (社)日本麻酔科学会東海・北陸支部第4回学術集会
- Place of Presentation
  名古屋
- Year and Date
  2007-02-17
- Data Source
  KAKENHI-PROJECT-19591782
[Presentation] モルモット心室筋遅延整流型カリウムチャネル電流に対するプロポフォールの抑制作用2007
- Author(s)
  畠山登, 松田直之, 桜谷文香, 木村純子, 服部裕一
- Organizer
  第58回日本薬理学会北部会総会
- Place of Presentation
  札幌
- Year and Date
  2007-09-27
- Data Source
  KAKENHI-PROJECT-19591782
[Presentation] 敗血症モルモット心房筋細胞におけるカルシウムチャネルの変化についての検討(社)日本麻酔科学会第54回学術集会2007
- Author(s)
  畠山登, 松田直之, 山田正名, 渋谷伸子, 青木優太, 山崎光章
- Organizer
  (社)日本麻酔科学会第54回学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19591782
[Presentation] 急性肺障害に対するステロイド治療効果の検討2007
- Author(s)
  松田直之, 畠山登, 釈永清志, 山崎光章
- Organizer
  (社)日本麻酔科学会東海・北陸支部第4回学術集会
- Place of Presentation
  名古屋
- Year and Date
  2007-02-17
- Data Source
  KAKENHI-PROJECT-19591782
[Presentation] Studies on Ionic Channel Currents of Single Atrial Myocyte in Septic Guinea Pig2007
- Author(s)
  Hatakeyama N, Matsuda N, Aoki Y, Momose Y, Yamazaki M
- Organizer
  2007 American Society of Anesthesiologists Annual Meeting
- Place of Presentation
  San Francisco CA, USA
- Data Source
  KAKENHI-PROJECT-19591782
[Presentation] 周術期・集中治療における超短時間作用型β1遮断薬の使用2007
- Author(s)
  畠山登
- Organizer
  第2回富山県周術期管理フォーラム
- Place of Presentation
  富山
- Year and Date
  2007-03-16
- Data Source
  KAKENHI-PROJECT-19591782
[Presentation] 敗血症マウスにおけるヒスタミンH4受容体を介した主要臓器の抗炎症作用2007
- Author(s)
  松田直之, 畠山登, 菅野正寛, 釈永清志, 廣田弘毅, 山崎光章
- Organizer
  (社)日本麻酔科学会第54回学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19591782
[Presentation] 急性膵炎の心房筋における感染性2ndアタックの機構2005
- Author(s)
  松田直之, 畠山登, 釈永清志, 山崎光章
- Organizer
  第28回日本循環制御医学会総会
- Place of Presentation
  和歌山
- Data Source
  KAKENHI-PROJECT-19591782
[Presentation] 炎症と不整脈
- Author(s)
  畠山　登
- Organizer
  日本循環制御医学会
- Place of Presentation
  名古屋
- Year and Date
  2015-06-04 – 2015-06-05
- Invited
- Data Source
  KAKENHI-PROJECT-24592362

1. SHIBUYA Nobuko (40178926)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
2. YAMAZAKI Mitsuaki (70158145)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. KINOSHITA Hiroyuki (70291490)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
4. ITO Yusuke (70018307)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. NARITA Minoru (40318613)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. MATSUDA Naoyuki (50332466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 25 results
7. KITAJIMA Isao (50214797)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NIIMI Hideki (50401865)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. IRANAMI Hiroshi (30193692)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. AZMA Toshiharu (60284197)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. AOKI Yuta (10621667)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. YAMAMOTO Seiji (10456361)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. NAKAHATA Katsutoshi (70332971)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HIROTA Koki (30218854)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. MOMOSE Yasunori (50020813)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NAGAKAWA Tamotsu (90237503)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HATAKEYAMA Noboru 畠山 登

Research Projects

Research Products

Co-Researchers

敗血症性心筋症の病態生理学的解明およびカテコラミン類修飾作用の研究Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Effect of micro-RNA on tachyarrhythmia in septic condition.Principal Investigator

Principal Investigator

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Research Institution

Role of astrocyte metabolism in the constitution of long-term memory and the molecular pharmacological effect of anesthetics

Principal Investigator

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Research Institution

Therapeutic strategy for the chronic pain through the neurogenesis of the central nervous system in enriched environment

Principal Investigator

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Research Institution

Mechanisms of oxidative stress in the human arteries from patients with metabolic syndrome and the treatment using a gene therapy

Principal Investigator

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Research Institution

Effects of septic condition on pacemaking cell.-Anti-arrhythmic strategy by gene-based treatments-Principal Investigator

Principal Investigator

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Research Institution

Development of the hypersensitive and rapid detection method for NF-κB activation using by Fluorescence Correlation Spectroscopy and its application to the emergency medicine

Principal Investigator

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Research Institution

Pathologic analysis of septic supraventricular tachyarrhythmia-clarification of pathogenesis and establishment of treatment-Principal Investigator

Principal Investigator

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Research Institution

Research on the mechanism of arrhythmia induced by general anesthetic on atrial pacemakerPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

イオンチャネルと細胞内情報伝達系に及ぼす全身麻酔薬の影響Principal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

The effects of anesthetics on transmembrane potential, transmembrane currents and EDHF in resistance and capacitance blood vessels (microcirculation)

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

虚血心筋に対する全身麻酔薬の細胞保護作用についての研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms of anesthetics on in situ normotensive vs hypertensive rat mesenteric vascular smooth muscle transmembrane potentials

Principal Investigator

Project Period (FY)

Research Category

HATAKEYAMA Noboru 畠山登

[Book] 吸入麻酔と心血管系.「吸入麻酔薬理から使用法まで」2003