OSAWA Hiroyuki 大澤博之

… Alternative Names

大澤博之オオサワヒロユキ

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Researcher Number	70260833
Other IDs
Affiliation (Current)	2025: 自治医科大学, 医学部, 客員教授
Affiliation (based on the past Project Information) *help	2006 – 2007: 自治医科大学, 医学部, 講師 2004 – 2005: 自治医科大学, 医学部, 助手 2001 – 2002: 自治医科大学, 医学部, 助手 1999: Jichi Med. Sch., Faculty Medicine, Research Assistant, 医学部, 助手 1994: 自治医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Gastroenterology Except Principal Investigator Gastroenterology / Gastroenterology
Keywords	Principal Investigator 膵管鏡 / 膵直視下生検 Except Principal Investigator CDX2 / トランスジェニックマウス / 腸上皮化生 / Sonic Hedgehog / 胃癌 / 転写因子 / Helicobacter pylori / miRNA … More / siRNA / Cdx2 / Gastric Cancer / Intestinal Metaplasia / Math 1 / transcription factor / intestinal metaplasia / CDX / CDX1 / Sonic Hedeehor / Math1 / COX2 / transgenic mouse / gastric carcinoma / Cdx1, 2 / Transcriptional Factor / Transgenic mouse / SHH / 分化型胃癌 / CDX 1,2 / transgenic mice / sulfatide / adhesin / 糖脂質 / ヘリコバクターピロリ / 接着 / スルファチド / アドヘシン / ペリコバクターピロリ / 嫌気培養 / 細菌叢 / 小腸 / 小腸ダブルバルーン内視鏡検査 / 嫌気性菌 / 通性菌 / 小腸細菌叢 Less

ヒト小腸の細菌叢と病態における変態
- Principal Investigator
  
  SUGANO Kentaro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Jichi Medical University
Studies on the molecular mechanisms leading to development of intestinal metaplasia
- Principal Investigator
  
  SUGANO Kentaro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Jichi Medical University
Study on the mechanism of development of differentiated adenocarcinoma from intestinal metaplasia
- Principal Investigator
  
  SUGANO Kentaro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  JICHI MEDICAL SCHOOL
To clarify the mechanism of the development of gastric well differentiated carcinoma from intestinal metaplasia
- Principal Investigator
  
  SATOH Kiichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  JICHI MEDICAL SCHOOL
Generation of intestinal metaplasia by ectopic expression of Cdx1 and Cdx2
- Principal Investigator
  
  SUGANO Kentaro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Jichi Medical School
Adhesin of Helicobacter pylon : Identification and therapeutic application
- Principal Investigator
  
  SUGANO Kentaro
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Jichi Medical School
  The University of Tokyo
膵疾患における膵管鏡直視下生検に関する研究Principal Investigator
- Principal Investigator
  
  大澤博之
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Jichi Medical University

All 2006 2005 2004 Other

All Journal Article

[Journal Article] Helicobacter pylori eradication induces marked increase in H^+/K^+-adenosine triphosphatase expression without altering parietal cell number in human gastric mucosa2006
- Author(s)
  Osawa, H
- Journal Title
  
  Gut 55
  
  Pages: 152-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390224
[Journal Article] Helicobacter pylori eradication induces marked increase in H^+/K^+-adenosine triphosphatase expression without altering parietal cell number in human gastric mucasa.2006
- Author(s)
  H.Osawa, H.Ohnishi, H.Mutoh, K.Sugano, et al.
- Journal Title
  
  Gut 55
  
  Pages: 152-157
- Data Source
  KAKENHI-PROJECT-18390224
[Journal Article] Helicobacter pylori eradication induces marked increase in H+/K+-adenosine triphosphatase expression without altering parietal cell number in human gastric mucosa2006
- Author(s)
  Osawa H
- Journal Title
  
  Gut 55
  
  Pages: 152-157
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390224
[Journal Article] Sonic hedgehog stimulates the proliferation of rat gastric mucosal cells through ERK activation by elevating intracellular calcium concentration2006
- Author(s)
  Osawa, H
- Journal Title
  
  Biochem. Biophy. Res. Comm 344
  
  Pages: 680-687
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390224
[Journal Article] Sonic hedgehog stimulates the proliferation of rat gastric mucosal cells through ERK activation by elevating intracellular calcium concentration.2006
- Author(s)
  H.Osawa, H.Ohnishi, K.Satoh, K.Sugano, et al.
- Journal Title
  
  Biochem. Biophy. Res. Comm. 344
  
  Pages: 680-687
- Data Source
  KAKENHI-PROJECT-18390224
[Journal Article] Sonic hedgehog stimulates the proliferation of rat gastric mucosal cells through ERK activation by elevating intracellular calcium concentration2006
- Author(s)
  Osawa H
- Journal Title
  
  Biochem. Biophy. Res. Comm 344
  
  Pages: 680-687
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390224
[Journal Article] Helicobacter pylori eradication induces marked increase in H+/K+- Adenosine triphosphatase expression without altering parietal cell number in human gastric mucosa.2006
- Author(s)
  Osawa H., Mutoh H., Satoh K., Sugano K.et al.
- Journal Title
  
  Gut 55(2)
  
  Pages: 152-157
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Pericryptal fibroblast sheath in intestinal metaplasia and gastric carcinoma.2005
- Author(s)
  Mutoh H, Sakurai S, Satoh K, Osawa H, Tomiyama T, Kita H, Yoshida T, Tamada K, Yamamoto H, Isoda N, Ido K, Sugano K.
- Journal Title
  
  Gut 54
  
  Pages: 33-39
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] Pericryptal fibroblast sheath in intestinal metaplasia and gastric carcinoma2005
- Author(s)
  Mutoh H, Sakurai S, Satoh K, Osawa H, Tomiyama T, Kita H, Yoshida T, Tamada K, Yamamoto H, Isoda N, Ido K, Sugano K.
- Journal Title
  
  Gut 54
  
  Pages: 33-39
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] Pericryptal fibroblast sheath in intestinal metaplasia and gastric carcinoma.2005
- Author(s)
  Mutoh H, Sakurai S, Satoh K, Osawa H, Tomiyama T, Kita H, Yoshida T, Tamada K, Yamamoto H, Isoda N, Ido K, Sugano K.
- Journal Title
  
  Gut. 54
  
  Pages: 33-39
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] Comparison of hemostatic effects by route of H2 receptor antagonist administration following endoscopic mucosal resection in patients with neoplastic gastric lesions.2005
- Author(s)
  K.Satoh, H.Osawa, K.Sugano, et al.
- Journal Title
  
  Aliment.Pharmcol.Ther. 21(Suppl 2)
  
  Pages: 105-110
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Pericryptal fibroblast sheath in intestinal metaplasia and gastric carcinoma.2005
- Author(s)
  Mutoh H, Satoh K, Osawa H, Sugano K.et al.
- Journal Title
  
  Gut 54(1)
  
  Pages: 33-39
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Pericryptal fibroblast sheath in intestinal metaplasia and gastric carcinoma2005
- Author(s)
  Mutoh H, Sakurai S, Satoh K, Osawa H, Tomiyama T, Kita H, Yoshida T, Tamada K, Yamamoto H, Isoda N, Ido K, Sugano K
- Journal Title
  
  Gut 54
  
  Pages: 33-39
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Histamine-2 receptor expression in gastric mucosa before and after Helicobacter pylori cure.2005
- Author(s)
  H.Osawa, H.Mutoh, K.Satoh, K.Sugano, et al.
- Journal Title
  
  Aliment.Pharmacol.Ther. 21(Suppl.2)
  
  Pages: 92-98
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Pericryptal fibroblast sheath in intestinal metaplasia and gastric carcinoma.2005
- Author(s)
  Mutoh H, Sakurai S, Satoh K, Osawa H, Tomiyama T, Kita H, Yoshida T, Tamada K, Yamamoto H, Isoda N, Ido K, Sugano K.
- Journal Title
  
  Gut. 54
  
  Pages: 33-39
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Pericryptal fibroblast sheath in intestinal metaplasia and gastric carcinoma.2005
- Author(s)
  H.Mutoh, S.Sakurai, K.Satoh, H.Osawa, T.Tomiyama, H.Kita, K.Sugano et al.
- Journal Title
  
  Gut 54
  
  Pages: 33-39
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Pericryptal fibroblast sheath in intestinal metaplasia and gastric carcinoma.2005
- Author(s)
  H.Mutoh, S.Sakurai, K.Satoh, H.Osawa, T.Tomiyama, H.Kita, K.Sugano et al.
- Journal Title
  
  Gut 54
  
  Pages: 33-39
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] Development of gastric carcinoma from intestinal metaplasia in Cdx2-transgenic mice.2004
- Author(s)
  Mutoh H, Sakurai S, Satoh K, Tamada K, Kita H, Osawa H, Tomiyama T, Sato Y, Yamamoto H, Isoda N, Yoshida T, Ido K, Sugano K.
- Journal Title
  
  Cancer Res. 64
  
  Pages: 7740-7747
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] Cdx1 induced intestinal metaplasia in the transgenic mouse stomach : Comparative study with Cdx2 transgenic mice.2004
- Author(s)
  H.Mutoh, S.Sakurai, K.Satoh, H.Osawa, Y.Hakamata, T.Takeuchi, K.Sugano
- Journal Title
  
  Gut 53・10
  
  Pages: 1416-1423
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Development of gastric carcinoma from intestinal metaplasia in Cdx2-transgenic mice.2004
- Author(s)
  H.Mutoh, S.Sakurai, K.Sato, K.Tamada, H.Kita, H.Osawa, K.Sugano et al.
- Journal Title
  
  Cancer Research 64
  
  Pages: 7740-7747
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] Cdx1 induced intestinal metaplasia in the transgenic mouse stomach : comparative study with Cdx2 transgenic mice2004
- Author(s)
  Mutoh H, Sakurai S, Satoh K, Osawa H, Hakamata Y, Takeuchi T, Sugano K
- Journal Title
  
  Gut 53
  
  Pages: 1416-1423
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Aberrant expression of CDX2 in the metaplastic epithelium and inflammatory mucosa of gallbladder.2004
- Author(s)
  H.Osawa, H.Kita, K.Satoh, H.Ohnishi, Y.Kaneko, H.Mutoh, K.Sugano et al.
- Journal Title
  
  Am.J.Surg.Pathol. 28・9
  
  Pages: 1253-1254
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Development of gastric carcinoma from intestinal metaplasia in Cdx2-transgenic mice.2004
- Author(s)
  Mutoh H, Sakurai S, Satoh K, Tamada K, Kita H, Osawa H, Tomiyama T, Sato Y, Yamamoto H, Isoda N, Yoshida T, Ido K, Sugano K.
- Journal Title
  
  Cancer Res. 64
  
  Pages: 7740-7747
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Cdx1 induced intestinal metaplasia in the transgenic mouse stomach : Comparative study with Cdx2 transgenic mice.2004
- Author(s)
  H.Mutoh, S.Sakurai, K.Satoh, H.Osawa, Y.Hakamata, T.Takeuchi, K.Sugano
- Journal Title
  
  Gut 53・10
  
  Pages: 1416-1423
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] Cdx1 induced intestinal metaplasia in the transgenic mouse stomach : comparative study with Cdx2 transgenic mice.2004
- Author(s)
  Mutoh H, Sakurai S, Satoh K, Osawa H, Hakamata Y, Takeuchi T, Sugano K.
- Journal Title
  
  Gut. 53
  
  Pages: 1416-1423
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] Development of gastric carcinoma from intestinal metaplasia in Cdx2-transgenic mice2004
- Author(s)
  Mutoh H, Sakurai S, Satoh K, Tamada K, Kita H, Osawa H, Tomiyama T, Sato Y, Yamamoto H, Isoda N, Yoshida T, Ido K, Sugano K.
- Journal Title
  
  Cancer Res. 64
  
  Pages: 7740-7747
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] Aberrant expression of CDX2 in the metaplastic epithelium and inflammatory mucosa of gallbladder.2004
- Author(s)
  H.Osawa, H.Kita, K.Satoh, H.Ohnishi, Y.Kaneko, H.Mutoh, K.Sugano et al.
- Journal Title
  
  Am.J.Surg.Pathol. 28・9
  
  Pages: 1253-1254
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] Cdx1 induced intestinal metaplasia in the transgenic mouse stomach : comparative study with Cdx2 transgenic mice.2004
- Author(s)
  Mutoh H, Sakurai S, Satoh K, Osawa H, Hakamata Y, Takeuchi T, Sugano K.
- Journal Title
  
  Gut. 53
  
  Pages: 1416-1423
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Development of gastric carcinoma from intestinal metaplasia in Cdx2-transgenic mice.2004
- Author(s)
  H.Mutoh, S.Sakurai, K.Sato, K.Tamada, H.Kita, H.Osawa, K.Sugano, et al.
- Journal Title
  
  Cancer Research 64
  
  Pages: 7740-7747
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Development of gastric carcinoma from intestinal metaplasia in Cdx2-transgenic mice2004
- Author(s)
  Mutoh H, Sakurai S, Satoh K, Tamada K, Kita H, Osawa H, Tomiyama T, Sato Y, Yamamoto H, Isoda N, Yoshida T, Ido K, Sugano K
- Journal Title
  
  Cancer Res. 64
  
  Pages: 7740-7747
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Cdx1 induced intestinal metaplasia in the transgenic mouse stomach : comparative study with Cdx2 transgenic mice2004
- Author(s)
  Mutoh H, Sakurai S, Satoh K, Osawa H, Hakamata Y, Takeuchi T, Sugano K.
- Journal Title
  
  Gut 53
  
  Pages: 1416-1423
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] Sonic Hedgehogs stimulates the proliferation of rat gastric mucosal cells through ERK activation by elevating intracellular calcium concentration.
- Author(s)
  Hiroyuki Osawa, Kiichi satoh, Kentaro Sugano, et al.
- Journal Title
  
  Biochem.Biophy.Res.Comm. (in press)
- Data Source
  KAKENHI-PROJECT-16390214

1. SUGANO Kentaro (60179116)

# of Collaborated Projects: 6 results

# of Collaborated Products: 28 results
2. SATOH Kiichi (50275707)

# of Collaborated Projects: 5 results

# of Collaborated Products: 27 results
3. MUTO Hiroyuki (50322392)

# of Collaborated Projects: 4 results

# of Collaborated Products: 25 results
4. KUMAKURA Yasuhisa (50275682)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. OONISHI Hirohide (00313023)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. YOSHIZAWA Mitsuyo (80406074)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 山本博徳 (10311937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 平井義一 (00127581)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 太田英孝 (60424016)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SATO Yukihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 福嶋康之

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 岩本美智子

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OSAWA Hiroyuki 大澤 博之

大澤 博之 オオサワ ヒロユキ

Research Projects

Research Products

Co-Researchers

ヒト小腸の細菌叢と病態における変態

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the molecular mechanisms leading to development of intestinal metaplasia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the mechanism of development of differentiated adenocarcinoma from intestinal metaplasia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

To clarify the mechanism of the development of gastric well differentiated carcinoma from intestinal metaplasia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Generation of intestinal metaplasia by ectopic expression of Cdx1 and Cdx2

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Adhesin of Helicobacter pylon : Identification and therapeutic application

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

膵疾患における膵管鏡直視下生検に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Helicobacter pylori eradication induces marked increase in H^+/K^+-adenosine triphosphatase expression without altering parietal cell number in human gastric mucosa2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Helicobacter pylori eradication induces marked increase in H^+/K^+-adenosine triphosphatase expression without altering parietal cell number in human gastric mucasa.2006

Author(s)

Journal Title

Data Source

[Journal Article] Helicobacter pylori eradication induces marked increase in H+/K+-adenosine triphosphatase expression without altering parietal cell number in human gastric mucosa2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Sonic hedgehog stimulates the proliferation of rat gastric mucosal cells through ERK activation by elevating intracellular calcium concentration2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Sonic hedgehog stimulates the proliferation of rat gastric mucosal cells through ERK activation by elevating intracellular calcium concentration.2006

Author(s)

Journal Title

Data Source

[Journal Article] Sonic hedgehog stimulates the proliferation of rat gastric mucosal cells through ERK activation by elevating intracellular calcium concentration2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Helicobacter pylori eradication induces marked increase in H+/K+- Adenosine triphosphatase expression without altering parietal cell number in human gastric mucosa.2006

Author(s)

Journal Title

Data Source

[Journal Article] Pericryptal fibroblast sheath in intestinal metaplasia and gastric carcinoma.2005

OSAWA Hiroyuki 大澤博之

大澤博之オオサワヒロユキ