Koike Manabu 小池学

… Alternative Names

Researcher Number	70280740
Other IDs
External Links
Affiliation (Current)	2022: 国立研究開発法人量子科学技術研究開発機構, 量子医科学研究所重粒子線治療研究部, 上席研究員
Affiliation (based on the past Project Information) *help	2019 – 2021: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所重粒子線治療研究部, 上席研究員(定常) 2017 – 2019: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所重粒子線治療研究部, 主幹研究員(定常) 2016: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所分子イメージング診断治療研究部, 主幹研究員(定常) 2015: 国立研究開発法人放射線医学総合研究所, 重粒子医科学センター, チームリーダー 2014: 独立行政法人放射線医学総合研究所, 放射線障害研究グループ, 主任研究員 … More
Review Section/Research Field	Principal Investigator 環境影響評価(含放射線生物学) / Risk sciences of radiation/Chemicals / Risk sciences of radiation and chemicals / Basic Section 63020:Radiation influence-related Except Principal Investigator Environmental pharmacy / Risk sciences of radiation/Chemicals / Biological Sciences / Carcinogenesis / Veterinary medical science / Risk sciences of radiation and chemicals … More
Keywords	Principal Investigator Ku70 / Ku80 / GFP / DSB / 電離放射線 / DNA repair / Kup70 / Kup80 / DNA修復 / Radiation … More Except Principal Investigator DNA二本鎖切断 / Ku / 分子シミュレーション / 皮膚 / Ahレセプター / ケラチノサイト / 創傷治癒 / DNA損傷認識 / 炎症 / 大腸がん / 盲腸 / ライブセルイメージング / Ku70 / NHEJ / keratinocyte / wound healing / 色素性乾皮症 A群 / 色素性乾皮症 G群 / 二重変異マウス / 疾患モデルマウス / ヌクレオチド除去修復 / 塩基除去修復 / 早期死亡 / 色素性乾皮症G群 / 老化 / ノックイン / 色素性乾皮症 / 突然変異 / 造血細胞系 / 骨髄キメラ / AhR / Blimp1 / 腸 / 皮脂腺 / 腸上皮細胞 / 分子動力学シミュレーション / Kuタンパク質 / 大腸癌 / Ah レセプター / サイトカイン / β-catenin / 三次元培養 / DNA損傷修復 / 損傷修復 / 損傷認識 / 放射線 / 伴侶動物 / 増感剤 / 犬 / XLF / XRCC4 / 像管財 / 上皮・間葉転換 / 上皮-間葉転換 / ダイオキシン / Ah receptor / Slug / skin / epidermal-mesenchymal transition / クラスターDNA損傷修復 / クラスターDNA損傷 / DNA修復 / DSB修復 / APサイト / 頭頸部がん / 重粒子線治療法 / 口腔扁平上皮癌 / 放射線治療抵抗性 / 頭頸部粘膜悪性黒色腫 / 放射線抵抗性 / EMT / 放射線治療 / 重粒子線 / 化学療法 / 口腔がん / 重粒子線治療 / 悪性粘膜黒色腫 / miRNA / 口腔粘膜悪性黒色腫 / 患者血漿サンプル / 予後予測 / 核移行シグナル (NLS) / Importin / アセチルリジン / 核移行シグナル(NLS) / アセチル化 / 腫瘍形成 / 食餌成分 / 発がん Less

AhRによる腫瘍抑制作用とその欠損マウスにおける腫瘍形成メカニズムの解析
- Principal Investigator
  
  生田統悟
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Research Institute for Clinical Oncology, Saitama Cancer Center
口腔粘膜悪性黒色腫の重粒子線治療を中心とした集学的治療法の開発
- Principal Investigator
  
  藤井万紀子
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Hiroshima University
DNA二本鎖切断修復タンパク質Ku70の核移行制御機構の解明
- Principal Investigator
  
  藤本浩文
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  National Institute of Infectious Diseases
非侵襲生体イメージング法による生体内修復機構の解明：次世代DSBセンサーマウスPrincipal Investigator
- Principal Investigator
  
  小池学
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology
Theoretical and experimental analysis of the binding efficiency of Ku protein to radiation induced clustered DNA damages
- Principal Investigator
  
  Fujimoto Hirofumi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  National Institute of Infectious Diseases
Establishment of the multidisciplinary treatment for oral cancer using a heavy particle ion radiation therapy
- Principal Investigator
  
  Fujii Makiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Hiroshima University
Development of a sensor mouse model of DNA damage : next-generation DSB sensor mousePrincipal Investigator
- Principal Investigator
  
  KOIKE MANABU
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology
Fundamental study for the development of new radiosensitizers based on the molecular mechanism of DNA double strand break repair of companion animals
- Principal Investigator
  
  KOIKE AKI
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Veterinary medical science
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology
A paradigm shift by two Ku80: New model of the radiation-induced DNA damage response mechanism in human cellsPrincipal Investigator
- Principal Investigator
  
  KOIKE MANABU
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  National Institute of Radiological Sciences
Structural analysis of the binding mechanism of the Ku protein to DNA that contains overhangs in its end
- Principal Investigator
  
  FUJIMOTO HIROFUMI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  National Institute of Infectious Diseases
Suppression of colon tumorigenesis by Ah receptor
- Principal Investigator
  
  IKUTA Togo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Carcinogenesis
- Research Institution
  Research Institute for Clinical Oncology, Saitama Cancer Center
Structural analysis of the interaction between the Ku protein and DNA
- Principal Investigator
  
  FUJIMOTO Hirofumi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  National Institute of Infectious Diseases
Development of a novel DNA damage sensor mouse model.Principal Investigator
- Principal Investigator
  
  KOIKE Manabu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  National Institute of Radiological Sciences
Expression and Function of the Ah receptor
- Principal Investigator
  
  IKUTA Togo
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Research Institute for Clinical Oncology, Saitama Cancer Center
DNA double-strand break repair proteins in mitochondria of mammalian cellsPrincipal Investigator
- Principal Investigator
  
  KOIKE MANABU
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  National Institute of Radiological Sciences
Biological function of Ah receptor
- Principal Investigator
  
  IKUTA Togo
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Research Institute for Clinical Oncology, Saitama Cancer Center
GFPにより可視化した非相同末端結合蛋白質によるDNA損傷認識機構に関する研究Principal Investigator
- Principal Investigator
  
  小池学
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  National Institute of Radiological Sciences
XPG欠損マウスを用いたヌクレオチド除去修復と塩基除去修復の相互作用の解析
- Principal Investigator
  
  塩見忠博
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Radiological Sciences
放射線に応答し細胞内局在を変化するDNA二重鎖切断修復蛋白質の同定と機能解析Principal Investigator
- Principal Investigator
  
  小池学
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  National Institute of Radiological Sciences
遺伝子ターゲッティング法を用いた電離放射線高感受性修復欠損マウス系統の樹立Principal Investigator
- Principal Investigator
  
  小池学
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  National Institute of Radiological Sciences
遺伝子ターゲッティング法を用いた電離放射線高感受性修復欠損マウス系統の樹立Principal Investigator
- Principal Investigator
  
  小池学
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  National Institute of Radiological Sciences

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2005 Other

All Journal Article Presentation

[Journal Article] Feline XLF accumulates at DNA damage sites in a Ku‐dependent manner.2019
- Author(s)
  Koke M., Yutoku Y., Koike A.
- Journal Title
  
  FEBS Open Bio
  
  Volume: －
- DOI
  10.1002/2211-5463.12589
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K00554
[Journal Article] Cloning, localization and focus formation at DNA damage sites of canine XLF2017
- Author(s)
  Koike M, Yutoku Y, Koike A.
- Journal Title
  
  J. Vet. Med. Sci.
  
  Volume: 79(1) Issue: 1 Pages: 22-28
- DOI
  10.1292/jvms.16-0440
- NAID
  130005289876
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26450438
[Journal Article] Cloning of canine Ku80 and its localization andaccumulation at DNA damage sites.2017
- Author(s)
  Koke, M., Yutoku, Y., Koike, A.
- Journal Title
  
  FEBS Open Bio.
  
  Volume: 7 Pages: 1854-1863
- DOI
  10.1002/2211-5463.12311
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K00554
[Journal Article] Cloning, localization and focus formation at DNA damage sites of canine Ku702017
- Author(s)
  Koike M, Yutoku Y, Koike A.
- Journal Title
  
  J. Vet. Med. Sci.
  
  Volume: 79(3) Issue: 3 Pages: 554-561
- DOI
  10.1292/jvms.16-0649
- NAID
  130005466302
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26450438, KAKENHI-PROJECT-16K00554
[Journal Article] Cloning, localization and focus formation at DNA damage sites of canine XRCC42017
- Author(s)
  Koike M, Yutoku Y, Koike A.
- Journal Title
  
  J. Vet. Med. Sci.
  
  Volume: 78(129) Issue: 12 Pages: 1865-1871
- DOI
  10.1292/jvms.16-0381
- NAID
  130005286386
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26450438
[Journal Article] Nuclear localization of mouse Ku70 in interphase cells and focus formation of mouse Ku70 at DNA damage sites immediately after irradiation2015
- Author(s)
  Koike M, Yutoku Y, Koike A.
- Journal Title
  
  J. Vet. Med. Sci.
  
  Volume: 77 Issue: 9 Pages: 1137-1142
- DOI
  10.1292/jvms.14-0651
- NAID
  130005100717
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24510078
[Journal Article] Impact of Amino Acid Substitutions in Two Functional Domains of Ku80: DNA-Damage-Sensing Ability of Ku80 and Survival after Irradiation2014
- Author(s)
  Koike M, Yutoku Y, Koike A.
- Journal Title
  
  J. Vet. Med. Sci.
  
  Volume: 76 Issue: 1 Pages: 51-56
- DOI
  10.1292/jvms.13-0283
- NAID
  130003362299
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24510078
[Journal Article] The Defect of Ku70 Affects Sensitivity to X-Ray and Radiation-Induced Caspase-Dependent Apoptosis in Lung Cells2013
- Author(s)
  Koike M, Yutoku Y, Koike A.
- Journal Title
  
  J. Vet. Med. Sci.
  
  Volume: 75(4) Issue: 4 Pages: 415-420
- DOI
  10.1292/jvms.12-0333
- NAID
  130002502180
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510078
[Journal Article] Ku80 attentuates cytotoxicity induced by green fluorescent protein transduction independently of non-homologous end joining.2013
- Author(s)
  Koike M*, Yutoku Y, Koike A.
- Journal Title
  
  FEBS Open Bio
  
  Volume: 3 Pages: 46-50
- DOI
  10.1016/j.fob.2012.12.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510077
[Journal Article] A possible overestimation of the effect of acetylation on lysine residues in KQ mutant analysis2012
- Author(s)
  Hirofumi Fujimoto, Mariko Higuchi, Manabu Koike, Hirotaka Ode, Miroslav Pinak, Juraj Kotulic Bunta, Toshiyuki Nemoto, Takashi Sakudoh, Naoko Honda, Hideaki Maekawa, Kimiaki Saito, Kozo Tsuchida
- Journal Title
  
  Journal of Computational Chemistry
  
  Volume: 33 Pages: 239-246
- DOI
  10.1002/jcc.21956
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21510063, KAKENHI-PROJECT-22310038
[Journal Article] Accumulation of Ku70 at DNA double-strand breaks in living epithelial cells2011
- Author(s)
  Manabu Koike, Yasutomo Yutoku, Aki Koike
- Journal Title
  
  Exp. Cell. Res
  
  Volume: 317 Pages: 2429-2437
- DOI
  10.1016/j.yexcr.2011.07.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21510063
[Journal Article] Establishment of Ku70-deficient lung epithelial cell lines and their hypersensitivity to low-dose X-irradiation2011
- Author(s)
  Koike M, Yutoku Y, Koike A
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Pages: 549-554
- NAID
  130000444626
- Data Source
  KAKENHI-PROJECT-20510059
[Journal Article] Establishment of Ku70-Deficient Lung Epithelial Cell Lines and Their Hypersensitivity to Low-Dose X-Irradiation2011
- Author(s)
  Manabu KOIKE, Yasutomo YUTOKU, Aki KOIKE
- Journal Title
  
  J. Vet. Med. Sci.
  
  Volume: 73 Issue: 5 Pages: 549-554
- DOI
  10.1292/jvms.10-0454
- NAID
  130000444626
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21510063
[Journal Article] Establishment of Ku70-Deficient Lung Epithelial Cell Lines and Their Hypersensitivity to Low-Dose X-Irradiation.2010
- Author(s)
  Koike M, Yutoku Y, Koike A.
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: in press
- NAID
  130000444626
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510059
[Journal Article] 放射線によるDNA二本鎖切断損傷とDNA修復酵素の挙動イメージング2005
- Author(s)
  伊吹裕子, 豊岡達士, 小池亜紀, 小池学
- Journal Title
  
  放射線科学 48
  
  Pages: 308-315
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510057
[Journal Article] Live cell imaging of DNA repair proteins and DNA double-strand breaks by ionizing irradiation2005
- Author(s)
  Ibuki Y, Toyooka T, Koike A, Koike M
- Journal Title
  
  Radiological Sciences 48
  
  Pages: 308-315
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17510057
[Journal Article] Ku70-binding site of Ku80 is required for the stabilization of Ku70 in the cytoplasm, for the nuclear translocation of Ku80, and for Ku80-dependent DNA repair.2005
- Author(s)
  Koike M, Koike A
- Journal Title
  
  Exp.Cell.Res. 305
  
  Pages: 266-276
- Data Source
  KAKENHI-PROJECT-17510057
[Journal Article] Ku70-binding site of Ku80 is required for the stabilization of Ku70 in the cytoplasm, for the nuclear translocation of Ku80, and for Ku80-dependent DNA repair.2005
- Author(s)
  Koike M, Koike A
- Journal Title
  
  Exp. Cell. Res. 305
  
  Pages: 266-276
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510057
[Journal Article] Establishment of Ku70-Deficient Lung Epithelial Cell Lines and Their Hypersensitivity to Low-Dose X-Irradiation.
- Author(s)
  Manabu KOIKE, Yasutomo YUTOKU, Aki KOIKE
- Journal Title
  
  Journal of Veterinary Medical Science 14
  
  Volume: in press
- NAID
  130000444626
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21510063
[Presentation] ブレオマイシン処理によるマウス腸組織のDNA二本鎖切断とアポトーシス細胞の検出2020
- Author(s)
  生田統悟、小池亜紀、小池学
- Organizer
  第４３回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K07437
[Presentation] DNA 修復機構と重粒子線がん治療の高精度化と適応拡大2020
- Author(s)
  小池学
- Organizer
  昭和大学学士会後援セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19K12337
[Presentation] 重粒子線治療に資する難治性がんのDNA修復能の変化を指標とする基礎研究2019
- Author(s)
  小池学，大森さくら，湯徳靖友，藤井万紀子
- Organizer
  平成30年度HIMAC共同利用研究成果発表会
- Data Source
  KAKENHI-PROJECT-19K12337
[Presentation] Acetylation of nuclear localization signal controls importin-mediated nuclear transport of Ku702019
- Author(s)
  Fujimoto H, Ikuta T, Koike A, Koike M
- Organizer
  The 16th International Congress of Radiation Research (ICRR2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K12337
[Presentation] 組織特異的DNA修復経路欠損マウスの開発-腸管上皮特異的Ku70欠損マウス2019
- Author(s)
  生田統悟、神田浩明、小池亜紀、小池学
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K11653
[Presentation] 重粒子線治療研究に資するDSBセンサー発現抑制細胞株を用いた細胞周期依存的な放射線感受性とDNA二本鎖切断損傷修復2018
- Author(s)
  湯徳靖友、大森さくら、小池亜紀、小池学
- Organizer
  アイソトープ・放射線研究発表会
- Data Source
  KAKENHI-PROJECT-16K00554
[Presentation] 有糸分裂期のDSB誘導性の染色体分配異常へのKuの関与2018
- Author(s)
  湯徳靖友、小池亜紀、大森さくら、小池学
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16K00554
[Presentation] 量子生命科学研究に向けたヒトと伴侶動物のDNA修復タンパク質Kuのライブセルイメージング：DSB損傷認識と翻訳後修飾変化2018
- Author(s)
  小池学
- Organizer
  生物学・光源・物性研究者による量子生物学勉強会（第２回）
- Invited
- Data Source
  KAKENHI-PROJECT-16K00554
[Presentation] 計算化学的手法を用いたKu70のアセチル化の効果の解析2017
- Author(s)
  藤本浩文，生田統悟，小池亜紀，小池学
- Organizer
  日本放射線影響学会第60回大会
- Data Source
  KAKENHI-PROJECT-16K00554
[Presentation] 細胞内の「放射線からDNAを守る仕組み」のビジュアル化 ―先端生命科学に基づくキャラクターを活用した教材化の可能性―2017
- Author(s)
  小池学，湯徳靖友，小池亜紀
- Organizer
  第54回アイソトープ・放射線研究発表会
- Data Source
  KAKENHI-PROJECT-16K00554
[Presentation] DNA修復蛋白質Kuに関する研究2017
- Author(s)
  小池学
- Organizer
  第2回QSTバイオ研究討論会
- Data Source
  KAKENHI-PROJECT-16K00554
[Presentation] 伴侶動物のDNA二本鎖切断修復の分子機構に基づく新しい放射線増感剤開発の基盤研究―DNA修復蛋白質XRCC4が損傷DNAに集積する様子のライブセルイメージング―2016
- Author(s)
  小池亜紀、湯徳靖友、小池学
- Organizer
  第159回日本獣医学会学術集会
- Place of Presentation
  日本大学生物資源科学部（神奈川県藤沢市）
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-26450438
[Presentation] ヒトのDNA修復蛋白質が損傷DNAを修復するために損傷部に集積する様子のライブセルイメージング-たった 1 つの遺伝子変異の影響-2013
- Author(s)
  小池学、湯徳靖友、小池亜紀
- Organizer
  第50回アイソトープ・放射線研究発表会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24510078
[Presentation] ヒトDNA修復蛋白質が損傷DNAを修復するために損傷部に集積する様子の可視化2012
- Author(s)
  小池学、湯徳　靖友、小池　亜紀
- Organizer
  第49回アイソトープ・放射線研究発表会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24510078
[Presentation] がん細胞への放射線作用とDNA修復機構2011
- Author(s)
  小池学
- Organizer
  昭和大学腫瘍分子研セミナー
- Place of Presentation
  東京
- Year and Date
  2011-10-17
- Data Source
  KAKENHI-PROJECT-21510063
[Presentation] がん細胞への放射線作用とDNA修復機構2011
- Author(s)
  小池学
- Organizer
  昭和大学腫瘍分子研セミナー
- Place of Presentation
  東京,品川
- Year and Date
  2011-10-17
- Data Source
  KAKENHI-PROJECT-21510063
[Presentation] エックス線照射したマウス個体におけるH2AXリン酸化修飾変化の組織特異性に関する研究2010
- Author(s)
  菅澤純、湯徳靖友、小池亜紀、小池学
- Organizer
  第47回アイソトープ・放射線研究発表会
- Place of Presentation
  日本科学未来館(東京都)
- Year and Date
  2010-07-09
- Data Source
  KAKENHI-PROJECT-20510059
[Presentation] 計算化学的手法を用いたKuタンパク質とDNAの相互作用部位の構造解析2010
- Author(s)
  藤本浩文, 樋口真理子, 小池学, Miroslav Pinak, Juraj Kotulic Bunta, 根本俊行, 前川秀彰, 作道隆, 高田直子, 土田耕三
- Organizer
  BMB2010事務局(第33回日本分子生物学会年会・第83回日本生化学会大会合同大会)
- Place of Presentation
  神戸ホトアイランド(兵庫県)
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21510063
[Presentation] 近紫外線レーザーマイクロ照射によるDNA修復酵素の挙動解析2009
- Author(s)
  小池学
- Organizer
  第4回高崎量子応用シンポジウム
- Place of Presentation
  高崎シティーギャラリー・コアホール
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-20510059
[Presentation] Molecular mechanisms of DNA double-strand break recognition process by NHEJ factor Ku in mammalian living cells2009
- Author(s)
  小池学
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-21510063
[Presentation] 近紫外線レーザーマイクロ照射によるDNA修復酵素の挙動解析2009
- Author(s)
  小池学
- Organizer
  第4回高崎量子応用研究シンポジウム
- Place of Presentation
  高崎シティギャラリー・コアホール
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-20510059
[Presentation] Molecular mechanisms of DNA double-strand break recognition process by NHEJ factor Ku in mammalian living cells2009
- Author(s)
  小池学
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  神奈川
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-21510063
[Presentation] 近紫外線レーザーマイクロ照射によるDNA修復酵素の挙動解析2009
- Author(s)
  小池学
- Organizer
  第4回高崎量子応用研究シンポジウム
- Place of Presentation
  群馬
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-21510063
[Presentation] 近紫外線レーザーマイクロ照射によるDNA修復酵素の挙動解析2009
- Author(s)
  小池学
- Organizer
  第4回高崎量子応用研究シンポジウム
- Place of Presentation
  高崎シティギャラリー・コアホール(群馬県)
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-21510063
[Presentation] DNA修復蛋白質XLF/NHEJ1が損傷DNAを修復するために損傷部に集積する様子のライブセルイメージングとDSB認識の分子機構の解明ー人間、家畜、伴侶動物、実験動物ー
- Author(s)
  小池　亜紀、湯徳　靖友、小池　学
- Organizer
  第157回日本獣医学会学術集会
- Place of Presentation
  北海道大学高等教育推進機構
- Year and Date
  2014-09-09 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-26450438
[Presentation] ヒトのDNA 修復蛋白質が損傷DNA を修復するために損傷部に集積する様子のライブセルイメージング－患者由来のXLF遺伝子変異の影響̶－
- Author(s)
  小池学、湯徳靖友、小池亜紀
- Organizer
  第51回アイソトープ・放射線研究発表会
- Place of Presentation
  東京
- Year and Date
  2014-07-07 – 2014-07-09
- Data Source
  KAKENHI-PROJECT-24510078

1. IKUTA Togo (00262072)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
2. KOIKE Aki (50415410)

# of Collaborated Projects: 4 results

# of Collaborated Products: 11 results
3. FUJIMOTO Hirofumi (60373396)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
4. Fujii Makiko (70406031)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SAKUDOH Takashi (70455393)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. TSUCHIDA Kozo (40231435)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. KAWAJIRI Kaname (50142112)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KOBAYASHI Yasuhito (80425652)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 塩見忠博 (40162573)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 高萩真彦 (30260235)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 森雅彦 (30270614)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 原田良信 (90192707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 小藤昌志 (10375066)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 今井高志 (50183009)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 柿本直也 (50324794)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 峯裕一 (60605989)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. Verdonschot RG (30756094)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. HIGUCHI Mariko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Koike Manabu 小池 学

KOIKE Manabu 小池 学

小池 学 コイケ マナブ

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

非侵襲生体イメージング法による生体内修復機構の解明：次世代DSBセンサーマウスPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a sensor mouse model of DNA damage : next-generation DSB sensor mousePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A paradigm shift by two Ku80: New model of the radiation-induced DNA damage response mechanism in human cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a novel DNA damage sensor mouse model.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Koike Manabu 小池学

KOIKE Manabu 小池学

小池学コイケマナブ