IMAI Takashi 今井高志

Researcher Number	50183009
Other IDs
Affiliation *help	2018 : 国立研究開発法人量子科学技術研究開発機構, その他部局等, 研究員 2018 : 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所病院, 室長(任常) 2016 – 2017 : 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所, 特別上席研究員(定常) 2015 : 国立研究開発法人放射線医学総合研究所, 重粒子センター, プログラムリーダー 2015 : 国立研究開発法人放射線医学総合研究所, 重粒子医科学センター先端粒子線生物研究プログラム, プロジェクトリーダー … More
Review Section/Research Field	Principal Investigator Radiation science / 医学一般 / Basic Section 52040:Radiological sciences-related Except Principal Investigator Radiation science / 環境影響評価(含放射線生物学) / Digestive surgery / Surgical dentistry
Keywords	Principal Investigator YAC / ポジショナルクローニング / MEN1 / 粒子線治療 / 浸潤 / 放射線治療 / 転移 / 転写制御 / アガロース顆粒法 / 癌抑制遺伝子 … More Except Principal Investigator ATM / CRE / bi-directional promoter / NPAT / NLS / 放射線障害 / 研究交流 / 防護剤 / 放射線治療 / 研究室訪問 / 生物学的効果比 / 早期肺癌 / Growth control / 転写調節 / case control study / Information exchange / radiotherapy / 研究情報交換 / 多因子発癌 / 予後 / 遺伝子発現 / 発がんプロモーター / Gene expression / risk factor / がん研究 / がん抑制遺伝子 / がん細胞 / 再生医療 / SABR / Bone invasion / 細胞内移行 / がん遺伝子 / ゲルシフト / 細胞遊走能 / Oral cancer / 炭素イオン線 / genetic polymorphism / 研究集会 / stereotactic / SBRT / 放射線感受性 / Oncogene / 急性増悪 / 放射線肺炎 / SNPｓ / radiation pneumonitis / マイクロアレイ / 遺伝子多型 / 蛋白質 / GFP / 放射線 / 細胞浸潤能 / 発癌感受性 / 乳癌 / NSCLC / 再生医学 / Microarray / Transcriptional regulation / 重粒子線治療 / 増殖因子 / 肺癌 / 生体分子 / 非小細胞肺癌 / 食道癌 / 増殖制御 / Cancer cells / Tumor virus / 間質性肺炎 / 単塩基多型 / 骨浸潤 / ルシフェラーゼ / リスク解析 / bi-directional / 北米 / 定位放射線治療 / 治療薬 / 口腔癌 / Tumor suppressor gene / lung cancer / ウイルス発がん / 遺伝子解析 / Tumor promoter / リスク因子 Less

癌放射線治療における稀で重篤な正常組織障害発症例のゲノムシーケンス解析Principal InvestigatorOngoing
- Principal Investigator
  
  今井高志
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology
Metabolome analysis of invaded pancreatic cancer cell line, PANC-1, after irradiationPrincipal Investigator
- Principal Investigator
  
  Imai Takashi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  National Institute of Radiological Sciences
Basic Research for Carbon-Ion Radiotherapy for Breast Cancer
- Principal Investigator
  
  Karasawa Kumiko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Tokyo Women's Medical University
  National Institute of Radiological Sciences
A study for single nucleotide polymorphism as a risk factor correlating to radiation pneumonitis after stereotactic body radiotherapy for non-small celllung cancer.
- Principal Investigator
  
  ONISHI Hiroshi
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  University of Yamanashi
Research on new mechanism for radioprotective effect of FGF12
- Principal Investigator
  
  NAKAYAMA Fumiaki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  National Institute of Radiological Sciences
The effects of X-ray or C-ion beams irradiation on invasive potential of human pancreatic cancer cell linesPrincipal Investigator
- Principal Investigator
  
  IMAI Takashi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  National Institute of Radiological Sciences
Identification of single nucletide polymorphisms that affect the esophageal carcinogenesis and clinical application for tailor-made medicine
- Principal Investigator
  
  MORI Takahiro
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Tohoku University
  Nihon University
Gene profile analysis concerning mandibular bone invasion of oral cancer
- Principal Investigator
  
  OMURA Ken
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tokyo Medical and Dental University
Analyses of transcriptional regulation and function of NPAT gene which shares a promoter witn ATM gene.
- Principal Investigator
  
  SAGARA Masashi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  National Institute of Radiological Sciences
多発性内分泌腺腫瘍症1型原因遺伝子の単離とその解析Principal Investigator
- Principal Investigator
  
  今井高志
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Institute of Radiological Sciences
多発性内分泌腺腫瘍症1型原因遺伝子の同定Principal Investigator
- Principal Investigator
  
  今井高志
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Japanese Foundation For Cancer Research
多発性内分泌腺腫瘍症1型の原因遺伝子の同定Principal Investigator
- Principal Investigator
  
  今井高志
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Japanese Foundation For Cancer Research
酵母人工染色体ベクタ-系を用いたハンチントン病原因遺伝子の単離とその構造解析Principal Investigator
- Principal Investigator
  
  今井高志
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Japanese Foundation For Cancer Research
Information Exchange on Cancer Research with North American Countries.
- Principal Investigator
  
  YAMAGUCHI Nobuo
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Institute of Medical Science, University of Tokyo
Construction of Ordered-Clones Library for Human Chromosome 21Principal Investigator
- Principal Investigator
  
  IMAI Takashi
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  医学一般
- Research Institution
  The Institute of Physical and Chemical Research

All 2017 2015 2014 2013 2012 2011 2010 2008 2006 Other

All Journal Article Presentation

[Journal Article] Metabolic characterization of invaded cells of the pancreatic cancer cell line, PANC-12017
- Author(s)
  Mayumi Fujita, Kaori Imadome, Takashi Imai
- Journal Title
  
  Cancer Science
  
  Volume : in press Pages : 961-971
- DOI
  10.1111/cas.13220
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K19833, KAKENHI-PROJECT-15KK0323, KAKENHI-PROJECT-25461934
[Journal Article] 乳癌の炭素イオン線感受性に関する研究2015
- Author(s)
  唐澤久美子、藤田真由美、荘司好美、堀本義哉、今井高志
- Journal Title
  
  平成28年度HIMAC共同研究利用研究報告書
  
  Volume : １ Pages : 1-2
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461935
[Journal Article] ヒト乳癌細胞株の放射線感受性評価に有用なHigh-density survival assay2015
- Author(s)
  藤田真由美、唐澤久美子、荘司好美、今留香織、今井高志
- Journal Title
  
  第24回乳癌基礎研究会報文集
  
  Volume : １ Pages : 1-4
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461935
[Journal Article] Carbon-ion irradiation suppresses migration and invasiveness of human pancreatic carcinoma cells MIAPaCa-2 via Rac1 and RhoA degradation2015
- Author(s)
  Fujita, M., Imadome, K., Shoji, Y., Isozaki, T., Endo, S., Yamada, S., and Imai, T.
- Journal Title
  
  International Journal of Radiation Oncology Biology Physics
  
  Volume : 未確定
- DOI
  10.1016/j.ijrobp.2015.05.009
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461934
[Journal Article] Biological effectiveness of carbon-ion radiation on various human breast cancer cell lines.2014
- Author(s)
  Karasawa K, Fujita M, Shoji Y, Horimoto Y, Inoue T, Imai T
- Journal Title
  
  Journal of Cell Science & Therapy
  
  Volume : 5（5） Pages : 1-5
- DOI
  10.4172/2157-7013.1000180
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461935
[Journal Article] Cellular Internalization of Fibroblast Growth Factor-12 Exerts Radioprotective Effects on Intestinal Radiation Damage Independently of FGFR Signaling2014
- Author(s)
  F.Nakayama, S.Umeda, T.Yasuda, M.Fujita, M.Asada, V.Meineke, T.Imamura, T.Imai.
- Journal Title
  
  International Journal of Radiation Oncology Biology Physics
  
  Volume : 88 Pages : 377-384
- DOI
  10.1016/j.ijrobp.2013.10.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591856
[Journal Article] Nitric oxide increase the invasion of pancreatic cancer cells via activation of the PI3K-AKT and RhoA pathways after carbon ion irradiation2014
- Author(s)
  Fujita, M., Imadome, K., Endo, S., Shoji, Y., Yamada, S., and Imai, T.
- Journal Title
  
  FEBS Letters
  
  Volume : 588 Pages : 3240-3250
- DOI
  10.1016/j.febslet.2014.07.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461934
[Journal Article] Upregulated expression of FGF13/FHF2 mediates resistance to platinum drugs in cervical cancer cells.2013
- Author(s)
  T.Okada, K.Murata, R.Hirose, C.Matsuda, T.Komatsu, M.Ikekita, M.Nakawatari, F.Nakayama, M.Wakatsuki, T.Ohno, S.Kato, T.Imai, T.Imamura
- Journal Title
  
  Scientific Reports
  
  Volume : 3 Pages : 2899-2899
- DOI
  10.1038/srep02899
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591856
[Journal Article] Carbon-ion radiation enhances migration ability and invasiveness of the pancreatic cancer cell, PANC-1, in vitro2012
- Author(s)
  Mayumi Fujita, Yoshimi Otsuka, Shigeru Yamada, Takashi Imai
- Journal Title
  
  Cancer Sci
  
  Volume : 103 Pages : 677-683
- DOI
  10.1111/j.1349-7006.2011.02190.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591624, KAKENHI-PROJECT-23791467, KAKENHI-PROJECT-22591394
[Journal Article] X-ray irradiation and Rho-kinase inhibitor additively induce invasiveness of the cells of the pancreatic cancer line2011
- Author(s)
  Mayumi Fujita, Yoshimi Otsuka, Shigeru Yamada, Takashi Imai
- Journal Title
  
  MIAPaCa-2, which exhibit mesenchymal and amoeboid motility, Cancer Science
  
  Volume : 102 Pages : 792-798
- DOI
  10.1111/j.1349-7006.2011.01852.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591624, KAKENHI-PROJECT-22591394, KAKENHI-PROJECT-23791467
[Journal Article] X-ray irradiation and Rho-kinase inhibitor additively induce invasiveness of the cells of the pancreatic cancer line, MIAPaCa-2, which exhibit mesenchymal and amoeboid motility2011
- Author(s)
  Mayumi Fujita, Yoshimi Otsuka, Shigeru Yamada, Mayumi Iwakawa, Takashi Imai
- Journal Title
  
  Cancer Science
  
  Volume : 102 Pages : 792-798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591394
[Journal Article] Upregulation of Stress-response Genes with Cell Cycle Arrest Induced by Carbon Ion Irradiation in Multiple Murine Tumors Models2008
- Author(s)
  Kaori Imadome, Mayumi Iwakawa, Kazunori Nojiri, Tomoaki Tamaki, Minako Sakai, Miyako Nakawatari, Takashi Moritake, Mitsuru Yanagisawa, Etsuko Nakamura, Hirohiko Tsujii, Takashi Imai
- Journal Title
  
  Cancer Biol Ther 7(2)
  
  Pages : 205-214
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390531
[Journal Article] Upregulation of stress-response genes with cell cycle arrest induced by carbon ion irradiation in multiple murine tumors models.2008
- Author(s)
  Imadome K, Iwakawa M, Nojiri K, Tamaki T, Sakai M, Nakawatari M, Moritake T, Yanagisawa M, Nakamura E, Tsujii H, Imai T
- Journal Title
  
  Cancer Biol Ther 7(2)
  
  Pages : 205-214
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390531
[Journal Article] A potential pitfall of MR imaging for assessing mandibular invasion of squamous cell carcinoma in the oral cavity.2006
- Author(s)
  Imaizumi A, Yoshino N, Yamada I, Nagumo K, Amagasa T, Omura K, Okada N, Kurabayashi T
- Journal Title
  
  Am J Neuroradiol 27(1)
  
  Pages : 114-122
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390531
[Journal Article] Gene expression profile changes correlating with radioresistance in human cell lines2006
- Author(s)
  Ken-ichi Ishikawa, Kumiko Saegusa, Yoshimi Otsuka, Atsuko Ishikawa, Seiko Kawai, Kaori Yasuda, Tomo Suga, Yuichi Michikawa, Masao Suzuki, Mayumi Iwakawa, Takashi Imai
- Journal Title
  
  Int J Radiat Oncol. Biol. Phys 65(1)
  
  Pages : 234-245
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390531
[Journal Article] A potential pitfall of MR imaging for assessing mandibular invasion of squamous cell carcinoma in the oral cavity2006
- Author(s)
  Imaizumi A, Yoshino N, Yamada I, Nagumo K, Amagasa T, Omura K, Okada N, Kurabayashi T
- Journal Title
  
  Am J Neuroradiol 27(1)
  
  Pages : 114-122
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390531
[Journal Article] Gene expression profile changes correlating with radioresistance in human cell lines2006
- Author(s)
  Ishikawa K, Saegusa K, Otsuka Y, Ishikawa A, Kawai S, Yasuda K, Suga T, Michikawa Y, Suzuki M, Iwakawa M, Imai T.
- Journal Title
  
  Int J Radiat Oncol Biol Phys 65(1)
  
  Pages : 234-245
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390531
[Journal Article] Prediction of Lymphatic Metastasis Based on Gene Expression Profile Analysis after Brachytberapy for Early-Stage Oral Tongue Carcinoma
- Author(s)
  Hiroshi Watanabe, Kaoru Mogushi, Masahiko Miura, Ryo-ichi Yoshimura, Tobru Kurabayashi, Hitoshi Shibuya, Hiroshi Tanaka, Shuhei Noda, Mayumi Iwakawa, Takashi Imai
- Journal Title
  
  Radiother Oncol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390531
[Journal Article] Gene expression analysis in human malignant melanoma cell lines exposed to carbon beams
- Author(s)
  Yoshitaka Matsumoto, Mayumi Iwakawa, Yoshiya Furusawa, Kenichi Ishikawa, Mizuho Aoki, Kaori Imadome, Izumi Matsumoto, Hirohiko Tsujii, Koichi Ando, Takashi Imai
- Journal Title
  
  Int J Radiat Biol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390531
[Journal Article] Prediction of lymphatic metastasis based on gene expression profile analysis after brachytherapy for early-stage oral tongue carcinoma
- Author(s)
  Watanabe H, Mogushi K, Miura M, Yoshimura R, Kurabayashi T, Shibuya H, Tanaka H, Noda S, Iwakawa M, Imai T
- Journal Title
  
  Radiother Oncol (In press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390531
[Journal Article] Gene expression analysis in human malignant melanoma cell lines exposed to carbon beams
- Author(s)
  Matsumoto Y, Iwakawa M, Furusawa Y, Ishikawa K, Aoki M, Imadome K, Matsumoto I, Tsujii H, Ando K, Imai T
- Journal Title
  
  Int J Radiat Biol (In press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390531
[Presentation] Biological effectiveness of carbon-ion radiation on various human breast cancer cell lines, 15th International Congress of Radiation Research2015
- Author(s)
  Karasawa K, Fujita M, Yoshimi S, Horimoto Y, Imai T
- Organizer
  15th International Congress of Radiation Research
- Place of Presentation
  京都国際会館　京都市左京区
- Year and Date
  2015-05-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461935
[Presentation] 重粒子線治療と化学療法の併用～放射線生物学的立場から2014
- Author(s)
  今井高志
- Organizer
  第12回日本臨床腫瘍学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2014-07-19
- Invited
- Data Source
  KAKENHI-PROJECT-25461934
[Presentation] Irradiation alters the invasive potential of PANC-1 cell line thorough NO and NOS-PI3K-AKT pathway activities in addition to the SerP activity2013
- Author(s)
  Mayumi Fujita, Kaori Imadome, Yoshimi Shoji, Takashi Imai
- Organizer
  Ninth AACR-Japanese Cancer Association Joint Conference
- Place of Presentation
  Hyatt Regency Maui(ハワイ、米国)
- Data Source
  KAKENHI-PROJECT-22591394
[Presentation] Irradiation alters the invasive potential of PANC-1 cell line thorough NO and NOS-PI3K-AKT pathway activities in addition to the SerP activity2013
- Author(s)
  Mayumi Fujita, Kaori Imadome, Yoshimi Shoji, Takashi Imai
- Organizer
  Ninth AACR-Japanese Cancer Association Joint Conference
- Place of Presentation
  Hyatt Regency Maui（ハワイ・米国）
- Data Source
  KAKENHI-PROJECT-22591394
[Presentation] 放射線治療効果の予測をめざして2012
- Author(s)
  今井高志
- Organizer
  第30回日本ヒト細胞学会学術集会(招待講演)
- Place of Presentation
  梅田スカイビル(大阪市)
- Data Source
  KAKENHI-PROJECT-22591394
[Presentation] 炭素線照射後のヒト膵癌由来細胞株MIAPaCa-2及びPANC-1の浸潤能変化とその機序2012
- Author(s)
  藤田真由美、今留香織、遠藤悟史、荘司好美、山田滋、今井高志
- Organizer
  第21回日本がん転移学会学術集会・総会
- Place of Presentation
  オリエンタルホテル広島(広島市)
- Data Source
  KAKENHI-PROJECT-22591394
[Presentation] The effects of irradiation on invasive potential of human pancreatic cancer cell lines2012
- Author(s)
  Mayumi Fujita, Kaori Imadome, Yoshimi Shoji, Takashi Imai
- Organizer
  MIAPaCa-2 and PANC-1, The 2nd Japan-China Symposium on Cancer Research
- Place of Presentation
  幕張メッセ(千葉市)
- Data Source
  KAKENHI-PROJECT-22591394
[Presentation] Irradiation alters the invasive potential of human pancreatic cancer cell lines thorough Rac1 and RhoA activities2012
- Author(s)
  Mayumi Fujita, Shigeru Yamada, Takashi Imai
- Organizer
  The 71st Annual Meeting of the Japanese Cancer Association (JCA)
- Place of Presentation
  ロイトン札幌（北海道）
- Data Source
  KAKENHI-PROJECT-22591394
[Presentation] Association of polymorphisms in hyaluronan receptor CD44 with radiotherapy effectiveness in patients with cervical cancer2012
- Author(s)
  Takashi Imai, Tomo Suga, Yoshimi Otsuka, Miyako Nakawatari, Atsuko Ishikawa
- Organizer
  CSH Asia / ICMS (The International Cancer Microenvironment Society) Joint Conference on Tumor Microenvironment
- Place of Presentation
  Suzhou Dushu Lake Conference Center（蘇州・中国）
- Data Source
  KAKENHI-PROJECT-22591394
[Presentation] 炭素線照射後のヒト膵癌由来細胞株MIAPaCa-2及びPANC-1の浸潤能変化とその機序2012
- Author(s)
  藤田真由美、今留香織、遠藤悟史、荘司好美、山田滋、今井高志
- Organizer
  第21回日本がん転移学会学術集会・総会
- Place of Presentation
  オリエンタルホテル広島（広島県）
- Data Source
  KAKENHI-PROJECT-22591394
[Presentation] 放射線治療効果の予測をめざして2012
- Author(s)
  今井高志
- Organizer
  日本ヒト細胞学会
- Place of Presentation
  梅田スカイビル（大阪府）
- Invited
- Data Source
  KAKENHI-PROJECT-22591394
[Presentation] Influence of multiple genetic polymorphisms on early adverse reaction in the gastrointestinal tract of patients with cervical cancer treated with pelvic radiation therapy2012
- Author(s)
  Takashi Imai, Atsuko Ishikawa, Tomo Suga, Yoshimi Shoji
- Organizer
  The 2nd Japan-China Symposium on Cancer Research
- Place of Presentation
  幕張メッセ（千葉県）
- Data Source
  KAKENHI-PROJECT-22591394
[Presentation] The effects of irradiation on invasive potential of human pancreatic cancer cell lines, MIAPaCa-2 and PANC-12012
- Author(s)
  Mayumi Fujita, Kaori Imadome, Yoshimi Shoji, Takashi Imai
- Organizer
  The 2nd Japan-China Symposium on Cancer Research
- Place of Presentation
  幕張メッセ（千葉県）
- Data Source
  KAKENHI-PROJECT-22591394
[Presentation] 放射線照射によるヒト癌由来細胞株の浸潤能変化とその抑制に有効な阻害剤の探索2012
- Author(s)
  藤田真由美、今留香織、遠藤悟史、荘司好美、今井高志
- Organizer
  HIMAC共同利用研究成果発表会
- Place of Presentation
  ホテルポートプラザちば（千葉県）
- Data Source
  KAKENHI-PROJECT-22591394
[Presentation] 放射線照射によるヒト大腸癌由来細胞株の浸潤能変化の検討2012
- Author(s)
  遠藤悟史、藤田真由美、山田滋、今留香織、篠藤誠、今井高志
- Organizer
  HIMAC共同利用研究成果発表会
- Place of Presentation
  ホテルポートプラザちば（千葉県）
- Data Source
  KAKENHI-PROJECT-22591394
[Presentation] Irradiation alters the invasive potential of human pancreatic cancer cell lines thorough Rac1 and RhoA activities2012
- Author(s)
  Mayumi Fujita, Shigeru Yamada, Takashi Imai
- Organizer
  The 71st Annual Meeting of the Japanese Cancer Association (JCA)
- Place of Presentation
  ロイトン札幌(札幌市)
- Data Source
  KAKENHI-PROJECT-22591394
[Presentation] Carbon-ion irradiation diminishes invasion of human pancreatic cancer cell line, MIAPaCa-2, through by inhibition of Rac1 and Rho signaling2011
- Author(s)
  Mayumi Fujita, Shigeru Yamada, Takashi Imai
- Organizer
  70th Annual Meeting of the Japanese Cancer Association (JCA)
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22591394
[Presentation] The effects of irradiation on invasive potential of human pancreatic cancer cell line, MIAPaCa-22011
- Author(s)
  Mayumi Fujita, Shigeru Yamada, Takashi Imai
- Organizer
  14th International Congress of Radiation Research(ICRR'2011)
- Place of Presentation
  The Palace of Culture and Science(Warsaw, POLAND)
- Year and Date
  2011-09-01
- Data Source
  KAKENHI-PROJECT-22591394
[Presentation] 放射線照射後の膵癌由来細胞MIAPaCa-2の浸潤能変化とその機序2011
- Author(s)
  藤田真由美、山田滋、今井高志
- Organizer
  第20回日本がん転移学会学術集会
- Place of Presentation
  アクトシティ浜松コングレスセンター(静岡県)
- Year and Date
  2011-06-30
- Data Source
  KAKENHI-PROJECT-22591394
[Presentation] The effects of irradiation on invasive potential of human pancreatic cancer cell line, MIAPaCa-22011
- Author(s)
  Mayumi Fujita, Shigeru Yamada, Takashi Imai
- Organizer
  14th International Congress of Radiation Research (ICRR'2011)
- Place of Presentation
  The Palace of Culture and Science (Warsaw, POLAND)
- Year and Date
  2011-09-01
- Data Source
  KAKENHI-PROJECT-22591394
[Presentation] Carbon-ion irradiation diminishes invasion of human pancreatic cancer cell line, MIAPaCa-2, through by inhibition of Rac1 and Rho signaling2011
- Author(s)
  Mayumi Fujita, Shigeru Yamada, Takashi Imai
- Organizer
  70th Annual Meeting of the Japanese Cancer Association (JCA)
- Place of Presentation
  Nagoya Congress Center(愛知県)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22591394
[Presentation] 放射線照射後の膵癌由来細胞MIAPaCa-2の浸潤能変化とその機序2011
- Author(s)
  藤田真由美、山田滋、今井高志
- Organizer
  第20回日本がん転移学会学術集会
- Place of Presentation
  アクトシティ浜松コングレスセンター(静岡県)
- Year and Date
  2011-06-30
- Data Source
  KAKENHI-PROJECT-22591394
[Presentation] Invasive potential of pancreatic cell line, MIA Pa Ca-2, was affected by irradiation2010
- Author(s)
  Mayumi Fujita, Shigeru Yamada, Mayumi Iwakawa, Takashi Imai
- Organizer
  69th Annual Meeting of Japanese Cancer Association
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22591394
[Presentation] Invasive potential of pancreatic cell line, MIA Pa Ca-2, was affected by irradiation2010
- Author(s)
  Mayumi Fujita, Shigeru Yamada, Mayumi Iwakawa, Takashi Imai
- Organizer
  69th Annual Meeting of Japanese Cancer Association
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22591394
[Presentation] 安定化FGF1による放射線脱毛の治療効果について
- Author(s)
  中山文明、梅田禎子、安田武嗣、今村亨、今井高志
- Organizer
  日本放射線影響学会第57回大会
- Place of Presentation
  かごしま県民交流センター
- Year and Date
  2014-10-01 – 2014-10-02
- Data Source
  KAKENHI-PROJECT-24591856
[Presentation] FGF12のFGFR非依存性な細胞内移行による小腸放射線障害防護効果
- Author(s)
  中山文明, 梅田禎子, 安田武嗣, 浅田眞弘, 今村亨, 今井高志
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートピアホテル
- Data Source
  KAKENHI-PROJECT-24591856
[Presentation] A Study of Carbon-ion Radiosensitivity
- Author(s)
  Karasaawa K, Fujita M, Shoji Y, Horimoto Y, Inoue T, Imai T
- Organizer
  第73回日本医学放射線学会総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-04-10 – 2014-04-13
- Data Source
  KAKENHI-PROJECT-25461935
[Presentation] FGF12の細胞内移行による放射線防護効果について
- Author(s)
  中山文明, 梅田禎子, 安田武嗣, 浅田眞弘, 今村亨, 今井高志
- Organizer
  日本放射線影響学会　第56回大会
- Place of Presentation
  ホテルクラウンパレス青森
- Data Source
  KAKENHI-PROJECT-24591856
[Presentation] 炭素線照射はGTP-bound Rac1 とRhoA のタンパク分解を介し膵癌由来細胞株MIAPaCa-2 の浸潤能を抑制する
- Author(s)
  藤田真由美、山田滋、今井高志
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25461934
[Presentation] ヒト膵癌由来細胞株PANC-1の炭素線照射による代謝変動の解析
- Author(s)
  藤田　真由美, 今留　香織, 荘司　好美, 今井　高志
- Organizer
  第１回がんと代謝研究会
- Place of Presentation
  山形県、鶴岡市
- Data Source
  KAKENHI-PROJECT-25461934
[Presentation] Role of nitric oxide in invasiveness of tumor cells irradiated with carbon-ion beams
- Author(s)
  Mayumi Fujita1, Kaori IFujita, M, Imadome, K, Shoji, Y, Cheng, R, Kesarwala, AK, Wink, DA, and Imai, T
- Organizer
  American Association for Cancer Research
- Place of Presentation
  Philadelphia, Pennsylvania, USA
- Year and Date
  2015-04-18 – 2015-04-22
- Data Source
  KAKENHI-PROJECT-25461934

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IMAI Takashi 今井 高志

Research Projects

Research Products

Co-Researchers

癌放射線治療における稀で重篤な正常組織障害発症例のゲノムシーケンス解析Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Metabolome analysis of invaded pancreatic cancer cell line, PANC-1, after irradiationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic Research for Carbon-Ion Radiotherapy for Breast Cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A study for single nucleotide polymorphism as a risk factor correlating to radiation pneumonitis after stereotactic body radiotherapy for non-small celllung cancer.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research on new mechanism for radioprotective effect of FGF12

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effects of X-ray or C-ion beams irradiation on invasive potential of human pancreatic cancer cell linesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of single nucletide polymorphisms that affect the esophageal carcinogenesis and clinical application for tailor-made medicine

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Gene profile analysis concerning mandibular bone invasion of oral cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analyses of transcriptional regulation and function of NPAT gene which shares a promoter witn ATM gene.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

多発性内分泌腺腫瘍症1型原因遺伝子の単離とその解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

多発性内分泌腺腫瘍症1型原因遺伝子の同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

多発性内分泌腺腫瘍症1型の原因遺伝子の同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

酵母人工染色体ベクタ-系を用いたハンチントン病原因遺伝子の単離とその構造解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Information Exchange on Cancer Research with North American Countries.

Principal Investigator

IMAI Takashi 今井高志