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Imai Takashi  今井 高志

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… Alternative Names

今井 高志  イマイ タカシ

IMAI Takashi  今井 高志

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Researcher Number 50183009
Other IDs
Affiliation (Current) 2022: 国立研究開発法人量子科学技術研究開発機構, QST病院 治療診断部, 室長
Affiliation (based on the past Project Information) *help 2019 – 2021: 国立研究開発法人量子科学技術研究開発機構, QST病院, 室長(任常)
2018 – 2019: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所 病院, 室長(任常)
2015: 国立研究開発法人放射線医学総合研究所, 重粒子センター, プログラムリーダー
2015: 国立研究開発法人放射線医学総合研究所, 重粒子医科学センター 先端粒子線生物研究プログラム, プロジェクトリーダー
2015: 国立研究開発法人放射線医学総合研究所, 重粒子医科学センター, プログラムリーダー … More
2015: 放射線医学総合研究所, 重粒子医科学センター・先端粒子線生物研究プログラム, プロジェクトリーダー
2014: 独立行政法人放射線医学総合研究所, 重粒子医科学センター, プログラムムリーダー
2011 – 2014: 独立行政法人放射線医学総合研究所, 重粒子医科学センター, プログラムリーダー
2012: 独立行政法人放射線医学総合研究所, 重粒子医科学センタ, 研究グループリーダ
2010: 独立行政法人放射線医学総合研究所, 重粒子医科学センター, グループリーダー
2008: 独立行政法人放射線医学総合研究所, 重粒子医科学センター, プロジェクトリーダー
2006 – 2008: 独立行政法人放射線医学総合研究所, 重粒子医科学センター, 研究リーダー
2007: 放射線医学総合研究所, フロンティア研究センター, プロジェクトリーダー
2007: National Institute of Radiological Sciences, Frontier Research Center, Project leader
2005 – 2006: 放射線医学総合研究所, フロンティア研究センター・放射線感受性遺伝子研究プロジェクト, プロジェクトリーダー
1999: NIRS, Genome Res., Sub-Group Leader, 第2研究グループ, サブグループリーダー
1998 – 1999: 放射線医学総合研究所, 第2研究グループ, 研究員
1994: 放射線医学総合研究所, 遺伝研究部, 主任研究官
1993: 財団法人癌研究會, 癌研究所・生化学部, 研究員
1992: 癌研究所, 室長
1991 – 1992: (財)癌研究会, 癌研究所・生化学部, 研究員
1988 – 1989: 理化学研究所, ジーンバンク室, 研究員 Less
Review Section/Research Field
Principal Investigator
Radiation science / 医学一般 / Basic Section 52040:Radiological sciences-related
Except Principal Investigator
Radiation science / Digestive surgery / 環境影響評価(含放射線生物学) / Surgical dentistry / Basic Section 57020:Oral pathobiological science-related
Keywords
Principal Investigator
YAC / ポジショナルクローニング / 放射線治療 / MEN1 / 粒子線治療 / 転移 / 浸潤 / がん / ハンチントン病 / 神経変性疾患 … More / 第4染色体 / 癌抑制遺伝子 / STS / エクソントラップ / Zooブロット / 多発性内分泌腺腫瘍症1型 / 11q13 / エクソントラップ法 / Znフィンガードメイン / 核局在シグナル / DNA結合タンパク質 / 多発性内分泌腺腫瘍症 / がん抑制遺伝子 / アルドステロン産性副腎腫瘍 / 11番染色体 / がんゲノム科学 / プロテアーゼ / Rhoキナーゼ / 放射線 / マトリックスメタロプロテアーゼ / 転写制御 / メタボローム解析 / 代謝経路 / 放射線誘導 / メタボローム / グルタチオン / 活性酸素 / PANC-1細胞 / 一酸化窒素 / ヒト21番染色体 / オ-ダ-・クロ-ン・ライブラリ- / 酵母人工染色体ベクター / コンティグマップ / アガロース顆粒法 / Alu配列 / ヒト、ハムスター雑種細胞 / 長鎖DNA / Human chromosome 21 / Ordered-clones library / 正常組織障害 / 遺伝子多型 / 乳がん / 前立腺がん / 排尿障害 / 有害反応リスク / ゲノムシーケンス / 骨代謝 / 遺伝因子 / DNAシーケンス / ゲノム / 放射線感受性 / 遺伝子変異 … More
Except Principal Investigator
重粒子線治療 / NPAT / ATM / bi-directional promoter / CRE / NLS / 食道癌 / 発癌感受性 / 単塩基多型 / 多因子発癌 / 予後 / 定位放射線治療 / 非小細胞肺癌 / 放射線肺炎 / 遺伝子多型 / リスク因子 / 遺伝子解析 / 早期肺癌 / リスク解析 / genetic polymorphism / stereotactic / lung cancer / radiation pneumonitis / SBRT / SABR / NSCLC / 肺癌 / 間質性肺炎 / 急性増悪 / SNPs / risk factor / case control study / radiotherapy / 放射線障害 / 防護剤 / 治療薬 / 増殖因子 / 再生医療 / 蛋白質 / 放射線 / 細胞内移行 / 再生医学 / 生体分子 / 炭素イオン線 / 乳癌 / 放射線感受性 / 生物学的効果比 / 細胞遊走能 / 細胞浸潤能 / 放射線治療 / 研究情報交換 / がん遺伝子 / ウイルス発がん / 発がんプロモーター / がん抑制遺伝子 / がん細胞 / 増殖制御 / 転写調節 / がん研究 / 研究交流 / 北米 / 研究室訪問 / 研究集会 / Information exchange / Oncogene / Tumor virus / Tumor promoter / Tumor suppressor gene / Cancer cells / Growth control / Transcriptional regulation / GFP / bi-directional / ルシフェラーゼ / ゲルシフト / 口腔癌 / 骨浸潤 / マイクロアレイ / 遺伝子発現 / Oral cancer / Bone invasion / Microarray / Gene expression / 悪性粘膜黒色腫 / miRNA / 口腔粘膜悪性黒色腫 / 患者血漿サンプル / 予後予測 Less
  • Research Projects

    (16 results)
  • Research Products

    (58 results)
  • Co-Researchers

    (87 People)
  •  口腔粘膜悪性黒色腫の重粒子線治療を中心とした集学的治療法の開発

    • Principal Investigator
      藤井 万紀子
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57020:Oral pathobiological science-related
    • Research Institution
      Hiroshima University
  •  癌放射線治療における稀で重篤な正常組織障害発症例のゲノムシーケンス解析Principal Investigator

    • Principal Investigator
      今井 高志
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      National Institutes for Quantum and Radiological Science and Technology
  •  Metabolome analysis of invaded pancreatic cancer cell line, PANC-1, after irradiationPrincipal Investigator

    • Principal Investigator
      Imai Takashi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      National Institute of Radiological Sciences
  •  Basic Research for Carbon-Ion Radiotherapy for Breast Cancer

    • Principal Investigator
      Karasawa Kumiko
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Tokyo Women's Medical University
      National Institute of Radiological Sciences
  •  A study for single nucleotide polymorphism as a risk factor correlating to radiation pneumonitis after stereotactic body radiotherapy for non-small celllung cancer.

    • Principal Investigator
      ONISHI Hiroshi
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      University of Yamanashi
  •  Research on new mechanism for radioprotective effect of FGF12

    • Principal Investigator
      NAKAYAMA Fumiaki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      National Institute of Radiological Sciences
  •  The effects of X-ray or C-ion beams irradiation on invasive potential of human pancreatic cancer cell linesPrincipal Investigator

    • Principal Investigator
      IMAI Takashi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      National Institute of Radiological Sciences
  •  Identification of single nucletide polymorphisms that affect the esophageal carcinogenesis and clinical application for tailor-made medicine

    • Principal Investigator
      MORI Takahiro
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Tohoku University
      Nihon University
  •  Gene profile analysis concerning mandibular bone invasion of oral cancer

    • Principal Investigator
      OMURA Ken
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Tokyo Medical and Dental University
  •  Analyses of transcriptional regulation and function of NPAT gene which shares a promoter witn ATM gene.

    • Principal Investigator
      SAGARA Masashi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      環境影響評価(含放射線生物学)
    • Research Institution
      National Institute of Radiological Sciences
  •  多発性内分泌腺腫瘍症1型原因遺伝子の単離とその解析Principal Investigator

    • Principal Investigator
      今井 高志
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      National Institute of Radiological Sciences
  •  多発性内分泌腺腫瘍症1型原因遺伝子の同定Principal Investigator

    • Principal Investigator
      今井 高志
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  多発性内分泌腺腫瘍症1型の原因遺伝子の同定Principal Investigator

    • Principal Investigator
      今井 高志
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  酵母人工染色体ベクタ-系を用いたハンチントン病原因遺伝子の単離とその構造解析Principal Investigator

    • Principal Investigator
      今井 高志
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Japanese Foundation For Cancer Research
  •  Information Exchange on Cancer Research with North American Countries.

    • Principal Investigator
      YAMAGUCHI Nobuo
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Institute of Medical Science, University of Tokyo
  •  Construction of Ordered-Clones Library for Human Chromosome 21Principal Investigator

    • Principal Investigator
      IMAI Takashi
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      医学一般
    • Research Institution
      The Institute of Physical and Chemical Research

All 2020 2019 2018 2017 2015 2014 2013 2012 2011 2010 2008 2006 1999 Other

All Journal Article Presentation Book Patent

  • [Book] 細胞周期と癌 p53、RB、チェックポイント制御の新展開1999

    • Author(s)
      今井高志
    • Total Pages
      179
    • Publisher
      羊土社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-10680532
  • [Journal Article] Individual response of humans to ionising radiation: governing factors and importance for radiological protection2020

    • Author(s)
      K. E. Applegate, W. Ruhm, A. Wojcik, M. Bourguignon, A. Brenner, K. Hamasaki, T. Imai, M. Imaizumi, T. Imaoka, S. Kakinuma, T. Kamada, N. Nishimura, N. Okonogi, K. Ozasa, C. E. Rube, A. Sadakane, R. Sakata, Y. Shimada, K. Yoshida & S. Bouffler
    • Journal Title

      Radiation and Environmental Biophysics

      Volume: 59 Pages: 185-209

    • DOI

      10.1007/s00411-020-00837-y

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07696
  • [Journal Article] Difference in Acquired Radioresistance Induction Between Repeated Photon and Particle Irradiation2019

    • Author(s)
      Sato Katsutoshi、Shimokawa Takashi、Imai Takashi
    • Journal Title

      Frontiers in Oncology

      Volume: 9

    • DOI

      10.3389/fonc.2019.01213

    • NAID

      120006768209

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07696
  • [Journal Article] Radiogenomics Consortium Genome-Wide Association Study Meta-Analysis of Late Toxicity After Prostate Cancer Radiotherapy2019

    • Author(s)
      Kerns S、Fachal L、Dorling L、Tsuji H、Imai T、Rosenstein B、West C et al.
    • Journal Title

      JNCI: Journal of the National Cancer Institute

      Volume: 112 Pages: 179-190

    • DOI

      10.1093/jnci/djz075

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07696
  • [Journal Article] Metabolic characterization of invaded cells of the pancreatic cancer cell line, PANC-12017

    • Author(s)
      Mayumi Fujita, Kaori Imadome, and Takashi Imai
    • Journal Title

      Cancer Science

      Volume: in press Pages: 961-971

    • DOI

      10.1111/cas.13220

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K19833, KAKENHI-PROJECT-15KK0323, KAKENHI-PROJECT-25461934
  • [Journal Article] 乳癌の炭素イオン線感受性に関する研究2015

    • Author(s)
      唐澤久美子、藤田真由美、荘司好美、堀本義哉、今井高志
    • Journal Title

      平成28年度HIMAC共同研究利用研究報告書

      Volume: 1 Pages: 1-2

    • Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25461935
  • [Journal Article] Carbon-Ion Irradiation Suppresses Migration and Invasiveness of Human Pancreatic Carcinoma Cells MIAPaCa-2 via Rac1 and RhoA Degradation2015

    • Author(s)
      Fujita, M., Imadome, K., Shoji, Y., Isozaki, T., Endo, S., Yamada, S., and Imai, T.
    • Journal Title

      Int J Radiat Oncol Biol Phys

      Volume: 未確定 Pages: 173-180

    • DOI

      10.1016/j.ijrobp.2015.05.009

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25461934, KAKENHI-PROJECT-15K19833
  • [Journal Article] ヒト乳癌細胞株の放射線感受性評価に有用なHigh-density survival assay2015

    • Author(s)
      藤田真由美、唐澤久美子、荘司好美、今留香織、今井高志
    • Journal Title

      第24回乳癌基礎研究会報文集

      Volume: 1 Pages: 1-4

    • Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25461935
  • [Journal Article] Cellular Internalization of Fibroblast Growth Factor-12 Exerts Radioprotective Effects on Intestinal Radiation Damage Independently of FGFR Signaling2014

    • Author(s)
      F.Nakayama, S.Umeda, T.Yasuda, M.Fujita, M.Asada, V.Meineke, T.Imamura, T.Imai.
    • Journal Title

      International Journal of Radiation Oncology Biology Physics

      Volume: 88 Pages: 377-384

    • DOI

      10.1016/j.ijrobp.2013.10.035

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591856
  • [Journal Article] Biological effectiveness of carbon-ion radiation on various human breast cancer cell lines.2014

    • Author(s)
      Karasawa K, Fujita M, Shoji Y, Horimoto Y, Inoue T, Imai T
    • Journal Title

      Journal of Cell Science & Therapy

      Volume: 5(5) Pages: 1-5

    • DOI

      10.4172/2157-7013.1000180

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25461935
  • [Journal Article] Nitric oxide increase the invasion of pancreatic cancer cells via activation of the PI3K-AKT and RhoA pathways after carbon ion irradiation2014

    • Author(s)
      Fujita, M., Imadome, K., Endo, S., Shoji, Y., Yamada, S., and Imai, T.
    • Journal Title

      FEBS Letters

      Volume: 588 Pages: 3240-3250

    • DOI

      10.1016/j.febslet.2014.07.006

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25461934
  • [Journal Article] Upregulated expression of FGF13/FHF2 mediates resistance to platinum drugs in cervical cancer cells.2013

    • Author(s)
      T.Okada, K.Murata, R.Hirose, C.Matsuda, T.Komatsu, M.Ikekita, M.Nakawatari, F.Nakayama, M.Wakatsuki, T.Ohno, S.Kato, T.Imai, T.Imamura
    • Journal Title

      Scientific Reports

      Volume: 3 Pages: 2899-2899

    • DOI

      10.1038/srep02899

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591856
  • [Journal Article] Carbon-ion radiation enhances migration ability and invasiveness of the pancreatic cancer cell, PANC-1, in vitro2012

    • Author(s)
      Mayumi Fujita, Yoshimi Otsuka, Shigeru Yamada, Takashi Imai
    • Journal Title

      Cancer Sci

      Volume: 103 Pages: 677-683

    • DOI

      10.1111/j.1349-7006.2011.02190.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591624, KAKENHI-PROJECT-22591394, KAKENHI-PROJECT-23791467
  • [Journal Article] X-ray irradiation and Rho-kinase inhibitor additively induce invasiveness of the cells of the pancreatic cancer line2011

    • Author(s)
      Mayumi Fujita, Yoshimi Otsuka, Shigeru Yamada, Takashi Imai
    • Journal Title

      Cancer Sci

      Volume: 102 Pages: 792-798

    • DOI

      10.1111/j.1349-7006.2011.01852.x

    • NAID

      10029292378

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591624, KAKENHI-PROJECT-22591394, KAKENHI-PROJECT-23791467
  • [Journal Article] X-ray irradiation and Rho-kinase inhibitor additively induce invasiveness of the cells of the pancreatic cancer line, MIAPaCa-2, which exhibit mesenchymal and amoeboid motility2011

    • Author(s)
      Mayumi Fujita, Yoshimi Otsuka, Shigeru Yamada, Mayumi Iwakawa, Takashi Imai
    • Journal Title

      Cancer Science

      Volume: 102 Pages: 792-798

    • NAID

      10029292378

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591394
  • [Journal Article] Upregulation of Stress-response Genes with Cell Cycle Arrest Induced by Carbon Ion Irradiation in Multiple Murine Tumors Models2008

    • Author(s)
      Kaori Imadome, Mayumi Iwakawa, Kazunori Nojiri, Tomoaki Tamaki, Minako Sakai, Miyako Nakawatari, Takashi Moritake, Mitsuru Yanagisawa, Etsuko Nakamura, Hirohiko Tsujii, Takashi Imai
    • Journal Title

      Cancer Biol Ther 7(2)

      Pages: 205-214

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390531
  • [Journal Article] Upregulation of stress-response genes with cell cycle arrest induced by carbon ion irradiation in multiple murine tumors models.2008

    • Author(s)
      Imadome K, Iwakawa M, Nojiri K, Tamaki T, Sakai M, Nakawatari M, Moritake T, Yanagisawa M, Nakamura E, Tsujii H, Imai T
    • Journal Title

      Cancer Biol Ther 7(2)

      Pages: 205-214

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390531
  • [Journal Article] Gene expression profile changes correlating with radioresistance in human cell lines2006

    • Author(s)
      Ishikawa K, Saegusa K, Otsuka Y, Ishikawa A, Kawai S, Yasuda K, Suga T, Michikawa Y, Suzuki M, Iwakawa M, Imai T.
    • Journal Title

      Int J Radiat Oncol Biol Phys 65(1)

      Pages: 234-245

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390531
  • [Journal Article] A potential pitfall of MR imaging for assessing mandibular invasion of squamous cell carcinoma in the oral cavity.2006

    • Author(s)
      Imaizumi A, Yoshino N, Yamada I, Nagumo K, Amagasa T, Omura K, Okada N, Kurabayashi T
    • Journal Title

      Am J Neuroradiol 27(1)

      Pages: 114-122

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390531
  • [Journal Article] Gene expression profile changes correlating with radioresistance in human cell lines2006

    • Author(s)
      Ken-ichi Ishikawa, Kumiko Saegusa, Yoshimi Otsuka, Atsuko Ishikawa, Seiko Kawai, Kaori Yasuda, Tomo Suga, Yuichi Michikawa, Masao Suzuki, Mayumi Iwakawa, Takashi Imai
    • Journal Title

      Int J Radiat Oncol. Biol. Phys 65(1)

      Pages: 234-245

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390531
  • [Journal Article] A potential pitfall of MR imaging for assessing mandibular invasion of squamous cell carcinoma in the oral cavity2006

    • Author(s)
      Imaizumi A, Yoshino N, Yamada I, Nagumo K, Amagasa T, Omura K, Okada N, Kurabayashi T
    • Journal Title

      Am J Neuroradiol 27(1)

      Pages: 114-122

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390531
  • [Journal Article] Prediction of lymphatic metastasis based on gene expression profile analysis after brachytherapy for early-stage oral tongue carcinoma

    • Author(s)
      Watanabe H, Mogushi K, Miura M, Yoshimura R, Kurabayashi T, Shibuya H, Tanaka H, Noda S, Iwakawa M, Imai T
    • Journal Title

      Radiother Oncol (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390531
  • [Journal Article] Prediction of Lymphatic Metastasis Based on Gene Expression Profile Analysis after Brachytberapy for Early-Stage Oral Tongue Carcinoma

    • Author(s)
      Hiroshi Watanabe, Kaoru Mogushi, Masahiko Miura, Ryo-ichi Yoshimura, Tobru Kurabayashi, Hitoshi Shibuya, Hiroshi Tanaka, Shuhei Noda, Mayumi Iwakawa, Takashi Imai
    • Journal Title

      Radiother Oncol (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390531
  • [Journal Article] Gene expression analysis in human malignant melanoma cell lines exposed to carbon beams

    • Author(s)
      Matsumoto Y, Iwakawa M, Furusawa Y, Ishikawa K, Aoki M, Imadome K, Matsumoto I, Tsujii H, Ando K, Imai T
    • Journal Title

      Int J Radiat Biol (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390531
  • [Journal Article] Gene expression analysis in human malignant melanoma cell lines exposed to carbon beams

    • Author(s)
      Yoshitaka Matsumoto, Mayumi Iwakawa, Yoshiya Furusawa, Kenichi Ishikawa, Mizuho Aoki, Kaori Imadome, Izumi Matsumoto, Hirohiko Tsujii, Koichi Ando, Takashi Imai
    • Journal Title

      Int J Radiat Biol (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390531
  • [Patent] 細胞膜透過性の線維芽細胞増殖因子の医療用途2013

    • Inventor(s)
      中山文明、梅田禎子、安田武嗣、藤田真由美、今井高志
    • Industrial Property Rights Holder
      放射線医学総合研究所
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-11-11
    • Overseas
    • Data Source
      KAKENHI-PROJECT-24591856
  • [Patent] 細胞膜透過性の線維芽細胞増殖因子の医療用途2012

    • Inventor(s)
      中山 文明、梅田 禎子、安田 武嗣、藤田 真由美、今井 高志
    • Industrial Property Rights Holder
      放射線医学総合研究所
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2012-259816
    • Filing Date
      2012-11-28
    • Data Source
      KAKENHI-PROJECT-24591856
  • [Presentation] Comparison of biological characteristics of regrown tumors after repetitive irradiation2018

    • Author(s)
      下川 卓志, 佐藤 克俊, 今井 高志
    • Organizer
      第77回 日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07696
  • [Presentation] FGF1/CPP-Cキメラタンパクによる膵癌重粒子線治療の有害事象の予防について2018

    • Author(s)
      中山 文明, 川野 光子, 三浦 太一, 藤田 真由美, 小池 幸子, 今留 香織, 石川 敦子, 安田 武嗣, 今村 亨, 今井 高志
    • Organizer
      第91回日本生化学会大会,
    • Data Source
      KAKENHI-PROJECT-18K07696
  • [Presentation] Biological effectiveness of carbon-ion radiation on various human breast cancer cell lines, 15th International Congress of Radiation Research2015

    • Author(s)
      Karasawa K, Fujita M, Yoshimi S, Horimoto Y, Imai T
    • Organizer
      15th International Congress of Radiation Research
    • Place of Presentation
      京都国際会館 京都市左京区
    • Year and Date
      2015-05-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461935
  • [Presentation] 重粒子線治療と化学療法の併用~放射線生物学的立場から2014

    • Author(s)
      今井高志
    • Organizer
      第12回日本臨床腫瘍学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2014-07-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-25461934
  • [Presentation] Irradiation alters the invasive potential of PANC-1 cell line thorough NO and NOS-PI3K-AKT pathway activities in addition to the SerP activity2013

    • Author(s)
      Mayumi Fujita, Kaori Imadome, Yoshimi Shoji, Takashi Imai
    • Organizer
      Ninth AACR-Japanese Cancer Association Joint Conference
    • Place of Presentation
      Hyatt Regency Maui(ハワイ・米国)
    • Data Source
      KAKENHI-PROJECT-22591394
  • [Presentation] Irradiation alters the invasive potential of PANC-1 cell line thorough NO and NOS-PI3K-AKT pathway activities in addition to the SerP activity2013

    • Author(s)
      Mayumi Fujita, Kaori Imadome, Yoshimi Shoji, Takashi Imai
    • Organizer
      Ninth AACR-Japanese Cancer Association Joint Conference
    • Place of Presentation
      Hyatt Regency Maui(ハワイ、米国)
    • Data Source
      KAKENHI-PROJECT-22591394
  • [Presentation] 放射線照射によるヒト大腸癌由来細胞株の浸潤能変化の検討2012

    • Author(s)
      遠藤悟史、藤田真由美、山田滋、今留香織、篠藤誠、今井高志
    • Organizer
      HIMAC共同利用研究 成果発表会
    • Place of Presentation
      ホテルポートプラザちば(千葉県)
    • Data Source
      KAKENHI-PROJECT-22591394
  • [Presentation] Irradiation alters the invasive potential of human pancreatic cancer cell lines thorough Rac1 and RhoA activities2012

    • Author(s)
      Mayumi Fujita, Shigeru Yamada, Takashi Imai
    • Organizer
      The 71st Annual Meeting of the Japanese Cancer Association (JCA)
    • Place of Presentation
      ロイトン札幌(札幌市)
    • Data Source
      KAKENHI-PROJECT-22591394
  • [Presentation] Influence of multiple genetic polymorphisms on early adverse reaction in the gastrointestinal tract of patients with cervical cancer treated with pelvic radiation therapy2012

    • Author(s)
      Takashi Imai, Atsuko Ishikawa, Tomo Suga, Yoshimi Shoji
    • Organizer
      The 2nd Japan-China Symposium on Cancer Research
    • Place of Presentation
      幕張メッセ(千葉県)
    • Data Source
      KAKENHI-PROJECT-22591394
  • [Presentation] 炭素線照射後のヒト膵癌由来細胞株MIAPaCa-2及びPANC-1の浸潤能変化とその機序2012

    • Author(s)
      藤田真由美、今留香織、遠藤悟史、荘司好美、山田滋、今井高志
    • Organizer
      第21回日本がん転移学会学術集会・総会
    • Place of Presentation
      オリエンタルホテル広島(広島県)
    • Data Source
      KAKENHI-PROJECT-22591394
  • [Presentation] 放射線照射によるヒト癌由来細胞株の浸潤能変化とその抑制に有効な阻害剤の探索2012

    • Author(s)
      藤田真由美、今留香織、遠藤悟史、荘司好美、今井高志
    • Organizer
      HIMAC共同利用研究 成果発表会
    • Place of Presentation
      ホテルポートプラザちば(千葉県)
    • Data Source
      KAKENHI-PROJECT-22591394
  • [Presentation] Irradiation alters the invasive potential of human pancreatic cancer cell lines thorough Rac1 and RhoA activities2012

    • Author(s)
      Mayumi Fujita, Shigeru Yamada, Takashi Imai
    • Organizer
      The 71st Annual Meeting of the Japanese Cancer Association (JCA)
    • Place of Presentation
      ロイトン札幌(北海道)
    • Data Source
      KAKENHI-PROJECT-22591394
  • [Presentation] 放射線治療効果の予測をめざして2012

    • Author(s)
      今井高志
    • Organizer
      日本ヒト細胞学会
    • Place of Presentation
      梅田スカイビル(大阪府)
    • Invited
    • Data Source
      KAKENHI-PROJECT-22591394
  • [Presentation] The effects of irradiation on invasive potential of human pancreatic cancer cell lines2012

    • Author(s)
      Mayumi Fujita, Kaori Imadome, Yoshimi Shoji, Takashi Imai
    • Organizer
      MIAPaCa-2 and PANC-1, The 2nd Japan-China Symposium on Cancer Research
    • Place of Presentation
      幕張メッセ(千葉市)
    • Data Source
      KAKENHI-PROJECT-22591394
  • [Presentation] 炭素線照射後のヒト膵癌由来細胞株MIAPaCa-2及びPANC-1の浸潤能変化とその機序2012

    • Author(s)
      藤田真由美、今留香織、遠藤悟史、荘司好美、山田滋、今井高志
    • Organizer
      第21回日本がん転移学会学術集会・総会
    • Place of Presentation
      オリエンタルホテル広島(広島市)
    • Data Source
      KAKENHI-PROJECT-22591394
  • [Presentation] Association of polymorphisms in hyaluronan receptor CD44 with radiotherapy effectiveness in patients with cervical cancer2012

    • Author(s)
      Takashi Imai, Tomo Suga, Yoshimi Otsuka, Miyako Nakawatari, Atsuko Ishikawa
    • Organizer
      CSH Asia / ICMS (The International Cancer Microenvironment Society) Joint Conference on Tumor Microenvironment
    • Place of Presentation
      Suzhou Dushu Lake Conference Center(蘇州・中国)
    • Data Source
      KAKENHI-PROJECT-22591394
  • [Presentation] The effects of irradiation on invasive potential of human pancreatic cancer cell lines, MIAPaCa-2 and PANC-12012

    • Author(s)
      Mayumi Fujita, Kaori Imadome, Yoshimi Shoji, Takashi Imai
    • Organizer
      The 2nd Japan-China Symposium on Cancer Research
    • Place of Presentation
      幕張メッセ(千葉県)
    • Data Source
      KAKENHI-PROJECT-22591394
  • [Presentation] 放射線治療効果の予測をめざして2012

    • Author(s)
      今井高志
    • Organizer
      第30回 日本ヒト細胞学会学術集会(招待講演)
    • Place of Presentation
      梅田スカイビル(大阪市)
    • Data Source
      KAKENHI-PROJECT-22591394
  • [Presentation] Carbon-ion irradiation diminishes invasion of human pancreatic cancer cell line, MIAPaCa-2, through by inhibition of Rac1 and Rho signaling2011

    • Author(s)
      Mayumi Fujita, Shigeru Yamada, Takashi Imai
    • Organizer
      70th Annual Meeting of the Japanese Cancer Association (JCA)
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-22591394
  • [Presentation] Carbon-ion irradiation diminishes invasion of human pancreatic cancer cell line, MIAPaCa-2, through by inhibition of Rac1 and Rho signaling2011

    • Author(s)
      Mayumi Fujita, Shigeru Yamada, Takashi Imai
    • Organizer
      70th Annual Meeting of the Japanese Cancer Association (JCA)
    • Place of Presentation
      Nagoya Congress Center(愛知県)
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-22591394
  • [Presentation] The effects of irradiation on invasive potential of human pancreatic cancer cell line, MIAPaCa-22011

    • Author(s)
      Mayumi Fujita, Shigeru Yamada, Takashi Imai
    • Organizer
      14th International Congress of Radiation Research (ICRR'2011)
    • Place of Presentation
      The Palace of Culture and Science (Warsaw, POLAND)
    • Year and Date
      2011-09-01
    • Data Source
      KAKENHI-PROJECT-22591394
  • [Presentation] 放射線照射後の膵癌由来細胞MIAPaCa-2の浸潤能変化とその機序2011

    • Author(s)
      藤田真由美、山田滋、今井高志
    • Organizer
      第20回日本がん転移学会学術集会
    • Place of Presentation
      アクトシティ浜松コングレスセンター(静岡県)
    • Year and Date
      2011-06-30
    • Data Source
      KAKENHI-PROJECT-22591394
  • [Presentation] The effects of irradiation on invasive potential of human pancreatic cancer cell line, MIAPaCa-22011

    • Author(s)
      Mayumi Fujita, Shigeru Yamada, Takashi Imai
    • Organizer
      14th International Congress of Radiation Research(ICRR'2011)
    • Place of Presentation
      The Palace of Culture and Science(Warsaw, POLAND)
    • Year and Date
      2011-09-01
    • Data Source
      KAKENHI-PROJECT-22591394
  • [Presentation] Invasive potential of pancreatic cell line, MIA Pa Ca-2, was affected by irradiation2010

    • Author(s)
      Mayumi Fujita, Shigeru Yamada, Mayumi Iwakawa, Takashi Imai
    • Organizer
      69th Annual Meeting of Japanese Cancer Association
    • Place of Presentation
      大阪国際会議場(大阪府)
    • Year and Date
      2010-09-23
    • Data Source
      KAKENHI-PROJECT-22591394
  • [Presentation] 安定化FGF1による放射線脱毛の治療効果について

    • Author(s)
      中山文明、梅田禎子、安田武嗣、今村亨、今井高志
    • Organizer
      日本放射線影響学会第57回大会
    • Place of Presentation
      かごしま県民交流センター
    • Year and Date
      2014-10-01 – 2014-10-02
    • Data Source
      KAKENHI-PROJECT-24591856
  • [Presentation] 炭素線照射はGTP-bound Rac1 とRhoA のタンパク分解を介し膵癌由来細胞株MIAPaCa-2 の浸潤能を抑制する

    • Author(s)
      藤田真由美、山田滋、今井高志
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-25461934
  • [Presentation] FGF12の細胞内移行による放射線防護効果について

    • Author(s)
      中山文明, 梅田禎子, 安田武嗣, 浅田眞弘, 今村亨, 今井高志
    • Organizer
      日本放射線影響学会 第56回大会
    • Place of Presentation
      ホテルクラウンパレス青森
    • Data Source
      KAKENHI-PROJECT-24591856
  • [Presentation] A Study of Carbon-ion Radiosensitivity

    • Author(s)
      Karasaawa K, Fujita M, Shoji Y, Horimoto Y, Inoue T, Imai T
    • Organizer
      第73回日本医学放射線学会総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-04-10 – 2014-04-13
    • Data Source
      KAKENHI-PROJECT-25461935
  • [Presentation] FGF12のFGFR非依存性な細胞内移行による小腸放射線障害防護効果

    • Author(s)
      中山文明, 梅田禎子, 安田武嗣, 浅田眞弘, 今村亨, 今井高志
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸ポートピアホテル
    • Data Source
      KAKENHI-PROJECT-24591856
  • [Presentation] ヒト膵癌由来細胞株PANC-1の炭素線照射による代謝変動の解析

    • Author(s)
      藤田 真由美, 今留 香織, 荘司 好美, 今井 高志
    • Organizer
      第1回がんと代謝研究会
    • Place of Presentation
      山形県、鶴岡市
    • Data Source
      KAKENHI-PROJECT-25461934
  • [Presentation] Role of nitric oxide in invasiveness of tumor cells irradiated with carbon-ion beams

    • Author(s)
      Mayumi Fujita1, Kaori IFujita, M, Imadome, K, Shoji, Y, Cheng, R, Kesarwala, AK, Wink, DA, and Imai, T
    • Organizer
      American Association for Cancer Research
    • Place of Presentation
      Philadelphia, Pennsylvania, USA
    • Year and Date
      2015-04-18 – 2015-04-22
    • Data Source
      KAKENHI-PROJECT-25461934
  • 1.  OMURA Ken (10334434)
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  • 2.  中村 祐輔 (70217909)
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  • 47.  加藤 勝 (50233820)
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  • 48.  伊藤 嘉明 (80004612)
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  • 49.  森井 成人 (80220036)
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    # of Collaborated Products: 0 results
  • 50.  平井 久丸 (90181130)
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    # of Collaborated Products: 0 results
  • 51.  武部 啓 (10028318)
    # of Collaborated Projects: 1 results
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  • 52.  伊庭 英夫 (60111449)
    # of Collaborated Projects: 1 results
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  • 53.  清木 元治 (10154634)
    # of Collaborated Projects: 1 results
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  • 54.  武市 紀年 (40002133)
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  • 55.  石崎 寛治 (70111987)
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  • 56.  首藤 紘一 (50012612)
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  • 57.  菊池 章 (10204827)
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  • 58.  山口 政光 (00182460)
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  • 59.  安本 茂 (00112342)
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  • 60.  佐竹 正延 (50178688)
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  • 61.  山本 雅 (40134621)
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    # of Collaborated Products: 0 results
  • 62.  秋山 徹 (70150745)
    # of Collaborated Projects: 1 results
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  • 63.  藤井 万紀子 (70406031)
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  • 64.  小藤 昌志 (10375066)
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  • 65.  柿本 直也 (50324794)
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  • 66.  峯 裕一 (60605989)
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  • 67.  小池 学 (70280740)
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  • 68.  Verdonschot RG (30756094)
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  • 69.  KURIYAMA Kengo
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  • 70.  KOMIYAMA Takafumi
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  • 71.  TOMINAGA Rihito
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  • 72.  OGURI Mitsuhiko
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  • 73.  NONAKA Hotaka
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    # of Collaborated Products: 0 results
  • 74.  AOKI Shinichi
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  • 75.  MATSUMOTO Yasuo
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  • 76.  MATSUSHITA Haruo
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  • 77.  TAKAYAMA Kenji
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  • 78.  INOUE Tetsuya
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    # of Collaborated Products: 0 results
  • 79.  KATO Norio
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    # of Collaborated Products: 0 results
  • 80.  YAMASHITA Hideomi
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    # of Collaborated Products: 0 results
  • 81.  KARASAWA Katsuyuki
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    # of Collaborated Products: 0 results
  • 82.  EBARA Takeshi
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    # of Collaborated Products: 0 results
  • 83.  UEKI Nami
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 84.  MATSUO Yukinori
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 85.  UMEDA Sachiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 86.  TSUKUMA Hideaki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 87.  YAMADA Shigeru
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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