Hibi Yoko 日比陽子

… Alternative Names

HIBI Yoko 日比陽子

日比陽子ヒビヨウコ

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Researcher Number	70295616
Other IDs
Affiliation (Current)	2025: 名古屋市立大学, 医薬学総合研究院(医学), 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 名古屋市立大学, 医薬学総合研究院(医学), 教授 2021: 名古屋市立大学, 大学院医学研究科, 教授 2018 – 2020: 名古屋市立大学, 大学院薬学研究科, 准教授 2014 – 2017: 名古屋大学, 医学部附属病院, 薬剤師 2011 – 2013: 名古屋大学, 医学部附属病院, 特任助教 2012: 名古屋大学, 医学部附属病院, 助教 2009: 名古屋大学, 大学院・医学系研究科, COE特任助教
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related / Pharmacology in pharmacy / General pharmacology Except Principal Investigator Basic Section 90140:Medical technology assessment-related / Basic Section 56030:Urology-related / Basic Section 47060:Clinical pharmacy-related / Basic Section 58010:Medical management and medical sociology-related / General pharmacology / Medical pharmacy / Psychiatric science
Keywords	Principal Investigator Npas4 / ストレス / 脳 / Neuronal PAS domain 4 / せん妄 / 神経分化 / 精神疾患 / NPAS4 / 急性腎障害 / 腎障害 … More / 発現誘導 / GABA / 薬学 / 神経科学 / 脳神経疾患 / プロモーターアッセイ / GABA受容体 / DNAメチル化亢進 / 遺伝子欠損マウス / promoter / glucocorticoid / stress / DNAメチル化 / プロモーター / グルココルチコイド / 転写制御 … More Except Principal Investigator ドパミン / 酵素免疫測定法 / 遺伝子改変マウス / 疾患マーカー / 遺伝子治療 / 精神疾患 / 神経疾患 / 新規分子 / 急性腎障害 / 抗菌薬 / 母集団薬物動態解析 / 治療薬物モニタリング / AUC / バンコマイシ / 投与設計 / TDM支援ソフト / TDM / グアニル酸シクラーゼ（GC） / 勃起不全（ED） / 勃起機能 / 光 / GC活性化剤 / 薬物動態 / 解糖系酵素 / がん代謝 / 腎細胞がん / ケミカルバイオロジー / ミトコンドリア / スーパーオキシド / 尿細管上皮細胞 / 薬剤性腎障害 / AI / 医療ビッグデータ / 新型コロナウイルス後遺症 / 新型コロナウイルス感染症 / D-セリン / 炎症性サイトカイン / 動物モデル / アストログリア / 神経－グリア相互作用 / エンドサイトーシス / IFITM3 / polyI:C / 神経-グリア相互作用 / アストログリア細胞 / 統合失調症 / 神経発達障害 / cDNAサブトラクション / ドパミントランスポーター / マウス / 薬物依存 / 生体分子 / 神経科学 / 新規遺伝子 Less

Development of Data-Driven Predictive System by AI Aimed at Mitigating Risks of COVID-19 Long-Term Effects
- Principal Investigator
  
  和知野千春
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58010:Medical management and medical sociology-related
- Research Institution
  Nagoya City University
急性腎障害によるせん妄発症機構の解明～神経分化関連因子NPAS4を鍵としてPrincipal Investigator
- Principal Investigator
  
  日比陽子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagoya City University
がん分子標的薬による腎障害の発現機序解明：BRAF阻害剤に着目した検討
- Principal Investigator
  
  真川明将
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagoya City University
Light-based ED treatment - Development of light-responsive GC activator and application to the treatment of refractory ED
- Principal Investigator
  
  堀田祐志
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Nagoya City University
Optimizing Therapeutic Indices of Antibiotics and Software Development for the Implementation of Dose Adjustment Based on Model-informed Precision Dosing
- Principal Investigator
  
  堀田康弘
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90140:Medical technology assessment-related
- Research Institution
  Nagoya City University
Elucidation of the mechanism of delirium onset caused by dysfunction of the stress-sensitive factor NPAS4 and development of therapeutic drugsPrincipal Investigator
- Principal Investigator
  
  HIBI YOKO
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagoya City University
Development of therapeutic agents for neuropsychiatric disorders targeting the stress-sensitive transcription factor NPAS4Principal Investigator
- Principal Investigator
  
  HIBI YOKO
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Nagoya City University
  Nagoya University
Association of mental disorder and decrease of Npas4Principal Investigator
- Principal Investigator
  
  HIBI YOKO
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Nagoya University
Role of neuronal PAS domain 4 (Npas4) in psychiatric disorder.Principal Investigator
- Principal Investigator
  
  HIBI YOKO
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
Functional analysis of IFITM3 in neurodevelopmental impairments
- Principal Investigator
  
  YAMADA Kiyofumi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
神経・精神疾患に関与する新規分子の機能解明および臨床応用への可能性
- Principal Investigator
  
  新田淳美
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  University of Toyama
新規薬物依存タンパクshatiの生理機能解析
- Principal Investigator
  
  新田淳美
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Psychiatric science
- Research Institution
  University of Toyama
  Nagoya University

[Book] 日本神経精神薬理学雑誌2009
- Author(s)
  日比陽子, ら
- Total Pages
  200
- Publisher
  脳由来神経栄養因子およびグリア細胞由来神経栄養因子と神経精神疾患との関係
- Data Source
  KAKENHI-PROJECT-21390045
[Book] 日本神経精神薬理学雑誌2009
- Author(s)
  日比陽子, ら
- Total Pages
  200
- Publisher
  脳由来神経栄養因子およびグリア細胞由来神経栄養因子と神経精神疾患との関係
- Data Source
  KAKENHI-PROJECT-19659292
[Journal Article] The Relationship between Changes in Serum Element Concentrations and Pathological Condition and Disease Status in Japanese Multiple Myeloma Patients: A Pilot Study and Literature Review2023
- Author(s)
  Yamamoto Yuko、Kondo Masahiro、Hotta Yuji、Tashiro Yuusuke、Sanagawa Akimasa、Kataoka Tomaya、Furukawa-Hibi Yoko、Ri Masaki、Komatsu Hirokazu、Iida Shinsuke、Kimura Kazunori
- Journal Title
  
  Asian Pacific Journal of Cancer Prevention
  
  Volume: 24 Issue: 7 Pages: 2493-2503
- DOI
  10.31557/apjcp.2023.24.7.2493
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06257
[Journal Article] Impact of body mass index on the severity of bexarotene‐associated hypertriglyceridemia: A post hoc analysis of an open‐labeled clinical study of combined bexarotene and phototherapy in Japanese patients with cutaneous T‐cell lymphoma2023
- Author(s)
  Sanagawa Akimasa、Hayakawa Tomoaki、Nishida Emi、Yamamoto Aya、Ikumi Kyoko、Mori Yukari、Hotta Yuji、Kimura Kazunori、Furukawa‐Hibi Yoko、Morita Akimichi
- Journal Title
  
  The Journal of Dermatology
  
  Volume: 50 Issue: 7 Pages: 917-926
- DOI
  10.1111/1346-8138.16801
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K06257
[Journal Article] Changes in zinc and manganese concentrations in cisplatin-induced acute kidney injury2023
- Author(s)
  Yamamoto Yuko、Hotta Yuji、Tomita Natsumi、Naiki-Ito Aya、Kitagawa Ayae、Kuboshiki Urara、Hagita Tamaki、Noda Misuzu、Sanagawa Akimasa、Kataoka Tomoya、Kondo Masahiro、Furukawa-Hibi Yoko、Takahashi Satoru、Kimura Kazunori
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 33 Pages: 101422-101422
- DOI
  10.1016/j.bbrep.2023.101422
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06963, KAKENHI-PROJECT-21K15319, KAKENHI-PROJECT-23K06257
[Journal Article] Evaluating the Effects of Low Carbohydrate and High Protein Diet on Erectile Function in Rats.2022
- Author(s)
  Kataoka T, Hidaka J, Suzuki J, Mori T, Nakamura D, Hotta Y, Sanagawa A, Maeda Y, Furukawa-Hibi Y, Kimura K.
- Journal Title
  
  Sex Med.
  
  Volume: 10 Issue: 2 Pages: 100500-100500
- DOI
  10.1016/j.esxm.2022.100500
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07181, KAKENHI-PROJECT-21K15319
[Journal Article] Effect of Replicative Senescence on the Expression and Function of Transporters in Human Proximal Renal Tubular Epithelial Cells2022
- Author(s)
  Sanagawa Akimasa、Hotta Yuji、Sezaki Rara、Tomita Natsumi、Kataoka Tomoya、Furukawa-Hibi Yoko、Kimura Kazunori
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 45 Issue: 11 Pages: 1636-1643
- DOI
  10.1248/bpb.b22-00322
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2022-11-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07181, KAKENHI-PROJECT-21K15319
[Journal Article] Effect of High Testosterone Levels on Endothelial Function in Aorta and Erectile Function in Rats2022
- Author(s)
  Kataoka Tomoya、Fukamoto Ayako、Hotta Yuji、Sanagawa Akimasa、Maeda Yasuhiro、Furukawa-Hibi Yoko、Kimura Kazunori
- Journal Title
  
  Sexual Medicine
  
  Volume: 10 Issue: 5 Pages: 100550-100550
- DOI
  10.1016/j.esxm.2022.100550
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07181, KAKENHI-PROJECT-20K09563, KAKENHI-PROJECT-21K15319
[Journal Article] Protective effects of tadalafil on damaged podocytes in an adriamycin-induced nephrotic syndrome model.2022
- Author(s)
  Tomita N, Hotta Y, Naiki-Ito A, Sanagawa A, Kataoka T, Furukawa-Hibi Y, Takahashi S, Kimura K.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 149 Issue: 2 Pages: 53-59
- DOI
  10.1016/j.jphs.2022.03.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08306, KAKENHI-PROJECT-19K07486, KAKENHI-PROJECT-21K15319, KAKENHI-PROJECT-20K07181, KAKENHI-PROJECT-22K06963
[Journal Article] Testosterone improved erectile function by upregulating transcriptional expression of growth factors in late androgen replacement therapy model rats2022
- Author(s)
  Kataoka Tomoya、Ito Hiroto、Mori Taiki、Hotta Yuji、Sanagawa Akimasa、Maeda Yasuhiro、Furukawa-Hibi Yoko、Kimura Kazunori
- Journal Title
  
  International Journal of Impotence Research
  
  Volume: - Issue: 4 Pages: 437-442
- DOI
  10.1038/s41443-022-00627-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07181
[Journal Article] Gosha-Jinki-Gan Improved Erectile Dysfunction Caused by Anti-Cancer Agent Oxaliplatin by Decreasing Transcriptional Expression of Phosphodiesterase-5 in Rats.2022
- Author(s)
  Kataoka T, Kawaki Y, Kito Y, Suzuki J, Mori T, Hotta Y, Sanagawa A, Kawade Y, Maeda Y, Furukawa-Hibi Y, Kimura K.
- Journal Title
  
  Sex Med.
  
  Volume: 10 Issue: 2 Pages: 100484-100484
- DOI
  10.1016/j.esxm.2021.100484
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07181, KAKENHI-PROJECT-21K15319, KAKENHI-PROJECT-20K09563
[Journal Article] Methylation analysis for postpartum depression : a case control study.2019
- Author(s)
  Nakamura Y, Nakatochi M, Kunimoto S, Okada T, Aleksic B, Toyama M, Shiino T, Morikawa M, Yamauchi A, Yoshimi A, Furukawa-Hibi Y, Nagai T, Ohara M, Kubota C, Yamada K, Ando M, Ozaki N.
- Journal Title
  
  BMC Psychiatry.
  
  Volume: 19 Issue: 1 Pages: 190-199
- DOI
  10.1186/s12888-019-2172-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08306, KAKENHI-PROJECT-17K16375, KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-16K10248, KAKENHI-PROJECT-17K16403
[Journal Article] Association between CYP2C19 genotype and the additional effect of cilostazol to clopidogrel resistance in neuroendovascular therapy2018
- Author(s)
  Tajima H, Izumi T, Miyachi S, Matsubara N, Ito M, Imai T, Nishihori M, Shintai K, Okamoto S, Araki Y, Kumakura Y, Furukawa-Hibi Y, Yamada K, Wakabayashi T.
- Journal Title
  
  Nagoya Journal of Medical Science
  
  Volume: 80 Issue: 2 Pages: 207-215
- DOI
  10.18999/nagjms.80.2.207
- NAID
  120006469000
- ISSN
  2186-3326
- URL
  https://nagoya.repo.nii.ac.jp/records/26018
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08306
[Journal Article] Neuronal PAS domain protein 4 (Npas4) controls neuronal homeostasis in pentylenetetrazole-induced epilepsy through the induction of Homer1a.2017
- Author(s)
  2.Shan W, Nagai T, Tanaka M, Itoh N, Furukawa-Hibi Y, Nabeshima T, Sokabe M, Yamada K.
- Journal Title
  
  J Neurochem.
  
  Volume: - Issue: 1 Pages: 19-33
- DOI
  10.1111/jnc.14274
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04031, KAKENHI-PROJECT-26460095, KAKENHI-PROJECT-16K15201, KAKENHI-PROJECT-16K21080, KAKENHI-PROJECT-17K08306, KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17K19483
[Journal Article] Behavioral impairment in SHATI/NAT8L knockout mice via dysfunction of myelination development2017
- Author(s)
  Sumi Kazuyuki、Uno Kyosuke、Noike Hiroshi、Tomohiro Takenori、Hatanaka Yasumaru、Furukawa-Hibi Yoko、Nabeshima Toshitaka、Miyamoto Yoshiaki、Nitta Atsumi
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 16872-16872
- DOI
  10.1038/s41598-017-17151-1
- NAID
  120006402037
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19801, KAKENHI-PROJECT-16K18933, KAKENHI-PROJECT-15H04662, KAKENHI-PROJECT-15K08090, KAKENHI-PROJECT-26460095
[Journal Article] Decreased DNA methylation in the Shati/Nat8l promoter in both patients with schizophrenia and a methamphetamine-induced murine model of schizophrenia-like phenotype2016
- Author(s)
  Uno K, Kikuchi Y, Iwata M, Uehara T, Matsuoka T, Sumiyoshi T, Okamoto Y, Jinno H, Takada T, Furukawa-Hibi Y, Nabeshima T, Miyamoto Y, Nitta A
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 6 Pages: e0157959-e0157959
- DOI
  10.1371/journal.pone.0157959
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04662, KAKENHI-PROJECT-26460240, KAKENHI-PROJECT-26461761, KAKENHI-PROJECT-15K15050, KAKENHI-PROJECT-15K08090, KAKENHI-PROJECT-26460095, KAKENHI-PROJECT-16K18933
[Journal Article] Conditioned medium from the stem cells of human dental pulp improves cognitive function in a mouse model of alzheimer’s disease.2015
- Author(s)
  Mita T, Furukawa-Hibi Y, Takeuchi H, Hattori H, Yamada K, Hibi H, Ueda M, Yamamoto A.
- Journal Title
  
  Behav Brain Res.
  
  Volume: 293 Pages: 189-197
- DOI
  10.1016/j.bbr.2015.07.043
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460095, KAKENHI-PROJECT-26670863, KAKENHI-PROJECT-25293408
[Journal Article] Aberrant DNA methylation is associated with a poor outcome in juvenile myelomonocytic leukemia.2015
- Author(s)
  Sakaguchi H, Muramatsu H, Okuno Y, Makishima H, Xu Y, Furukawa-Hibi Y, Wang X, Narita A, Yoshida K, Shiraishi Y, Doisaki S, Yoshida N, Hama A, Takahashi Y, Yamada K, Miyano S, Ogawa S, Maciejewski JP, Kojima S.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 12 Pages: e0145394-e0145394
- DOI
  10.1371/journal.pone.0145394
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460095, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-15H06324
[Journal Article] Stress increases DNA methylation of the neuronal PAS domain 4 (Npas4) gene.2015
- Author(s)
  Furukawa-Hibi Y, Nagai T, Yun J, Yamada K.
- Journal Title
  
  Neuroreport.
  
  Volume: 26 Issue: 14 Pages: 827-32
- DOI
  10.1097/wnr.0000000000000430
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460095, KAKENHI-PROJECT-25460093
[Journal Article] Induction of neuronal axon outgrowth by Shati/Nat8l by energy metabolism in mice cultured neurons.2015
- Author(s)
  Sumi K, Uno K, Matsumura S, Miyamoto Y, Furukawa-Hibi Y, Muramatsu S, Nabeshima T, Nitta A.
- Journal Title
  
  Neuroreport
  
  Volume: 26(13) Issue: 13 Pages: 740-746
- DOI
  10.1097/wnr.0000000000000416
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08090, KAKENHI-PROJECT-26460095, KAKENHI-PROJECT-15K15050, KAKENHI-PROJECT-15H04662, KAKENHI-PROJECT-26293213
[Journal Article] Deletion of SHATI/NAT8L increases dopamine D1 receptor on the cell surface in the nucleus accumbens, accelerating methamphetamine dependence2014
- Author(s)
  Toriumi K., Kondo M., Nagai T., Furukawa-Hibi Y., Mamiya T., Fukushima T., Takeda M., Nitta A., Yamada K., Nabeshima T.(他7名)
- Journal Title
  
  Int. J . Neuropsychopharmacol
  
  Volume: 17 Pages: 443-452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Overexpression of Shati/Nat8l, an N-acetyltransferase, in the nucleus accumbens attenuates the response to methamphetamine via activation of group II mGluRs in mice2014
- Author(s)
  Miyamoto Y., Ishikawa Y., Iegaki N., Sumi K., Fu K., Sato K., Furukawa-Hibi Y., Muramatsu S., Nabeshima T., Uno K., Nitta A.
- Journal Title
  
  Int. J. Neuropsychopharmacol.
  
  Volume: 17 Issue: 08 Pages: 1-12
- DOI
  10.1017/s146114571400011x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590299, KAKENHI-PROJECT-24590183, KAKENHI-PUBLICLY-25110729, KAKENHI-PROJECT-25860108, KAKENHI-PROJECT-26293213, KAKENHI-PROJECT-26460095
[Journal Article] SHATI/NAT8L regulates neurite outgrowth via microtubule stabilization2014
- Author(s)
  K Toriumi, M Ikami, M Kondo, A Mouri, T Koseki, D Ibi, Y Furukawa-Hibi, T Nagai, T Mamiya, A Nitta, K Yamada and T Nabeshima
- Journal Title
  
  Journal of Neuroscience Research
  
  Volume: 91 Issue: 12 Pages: 1525-1532
- DOI
  10.1002/jnr.23273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J03454, KAKENHI-PROJECT-23590299, KAKENHI-PROJECT-24590304
[Journal Article] Deletion of SHATI/NAT8L increases dopamine D1 receptor on the cell surface in the nucleus accumbens, accelerating methamphetamine dependence2014
- Author(s)
  Toriumi K, Kondo M, Nagai T, Hashimoto R, Ohi K, Song Z, Tanaka J, Mouri A, Koseki T, Yamamori H, Furukawa-Hibi Y, Mamiya T, Fukushima T, Takeda M, Nitta A, Yamada K, Nabeshima T
- Journal Title
  
  Int J Neuropsychopharmacol
  
  Volume: 17 Issue: 03 Pages: 443-453
- DOI
  10.1017/s1461145713001302
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-23590299, KAKENHI-PROJECT-24590304, KAKENHI-PROJECT-25293250, KAKENHI-PROJECT-25461730, KAKENHI-PROJECT-26460095
[Journal Article] Overexpression of Shati/Nat8l, an N-acetyltransferase, in the nucleus accumbens attenuates the response to methamphetamine via activation of group II mGluRs in mice2014
- Author(s)
  Miyamoto Y., Ishikawa Y., Iegaki N., Furukawa- Hibi Y., Nabeshima T., Uno K., Nitta A.(他4名)
- Journal Title
  
  Int. J . Neuropsychopharmacol
  
  Pages: 1-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Npas4 regulates Mdm2 and thus Dcx in experience-dependent olfactory bulb interneuron dendritic spine development.2014
- Author(s)
  Yoshihara S, Takahashi H, Nishimura N, Kinoshita M, Asahina R, Kitsuki M, Tatsumi K, Furukawa-Hibi Y, Hirai H, Nagai T, Yamada K and Tsuboi A.
- Journal Title
  
  Cell Reports
  
  Volume: 8 Issue: 3 Pages: 843-857
- DOI
  10.1016/j.celrep.2014.06.056
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24500385, KAKENHI-PROJECT-25290015, KAKENHI-PROJECT-25430010, KAKENHI-PROJECT-26460095
[Journal Article] アルツハイマー型認知症治療薬について2013
- Author(s)
  日比陽子
- Journal Title
  
  ファルマシア
  
  Volume: 49(6) Pages: 539-543
- NAID
  110010010583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Correlation of CYP2C19 Phenotype with Voriconazole Plasma Concentration in Children2013
- Author(s)
  Narita A., Muramatsu H., Sakaguchi H., Furukawa-Hibi Y., Yamada K. and Kojima S.(他9名)
- Journal Title
  
  J . Pediat. Hematol. Onc
  
  Volume: 35(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] SHATI/NAT8L regulates neurite outgrowth via microtubule stabilization2013
- Author(s)
  Toriumi K., Ikami M., Furukawa-Hibi Y., Nagai T., Mamiya T., Nitta A., Yamada K. and Nabeshima T.(他3名)
- Journal Title
  
  J . Neurosci. Res
  
  Volume: 91 Pages: 1525-1532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Neuronal PAS domain protein 4 (Npas4) regulates neurite outgrowth and phosphorylation of synapsin I2013
- Author(s)
  Yun, J., Nagai, T., Furukawa-Hibi, Y., Kuroda, K., Kaibuchi, K. and Yamada, K.
- Journal Title
  
  J . Biol. Chem
  
  Volume: 288 Pages: 2655-2664
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Neuronal PAS domain domain protein 4 (Npas4) regulates neurite outgrowth and phosphorylation of synapsin I.2013
- Author(s)
  Yun J, Nagai T, Furukawa-Hibi Y, Kuroda K, Kaibuchi K, Greenberg ME, and Yamada K
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Issue: 4 Pages: 2655-2664
- DOI
  10.1074/jbc.m112.413310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390046, KAKENHI-PROJECT-23590299, KAKENHI-PROJECT-23659135, KAKENHI-PROJECT-23790081, KAKENHI-PROJECT-25830051
[Journal Article] Transcriptional suppression of the neuronal PAS domain 4 (Npas4) gene by stress via the binding of agonist-bound glucocorticoid receptor to its promoter2012
- Author(s)
  Furukawa-Hibi, Y., Yun, J., Nagai, T. and Yamada, K.
- Journal Title
  
  J . Neurochem
  
  Volume: 123 Pages: 866-875
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Transcriptional suppression of the neuronal PAS domain 4 (Npas4) gene by stress via the binding of agonist-bound glucocorticoid receptor to its promoter2012
- Author(s)
  Furukawa-Hibi Y, Yun J, Nagai T, and Yamada K
- Journal Title
  
  J Neurochem
  
  Volume: 123 Issue: 5 Pages: 866-875
- DOI
  10.1111/jnc.12034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390046, KAKENHI-PROJECT-23590299, KAKENHI-PROJECT-23790081
[Journal Article] Somatic mosaicism for oncogenic NRAS mutations in juvenile myelomonocytic leukemia2012
- Author(s)
  Doisaki S, Muramatsu H, Shimada A, Takahashi Y, Mori-Ezaki M, Sato M, Kawaguchi H, Kinoshita A, Sotomatsu M, Hayashi Y, Furukawa-Hibi Y, Yamada K, Hoshino H, Kiyoi H, Yoshida N, Sakaguchi H, Narita A, Wang X, Ismael O, Xu Y, Nishio N, Tanaka M, Hama A, Koike K, Kojima S
- Journal Title
  
  Blood
  
  Volume: 120 Issue: 7 Pages: 1485-1488
- DOI
  10.1182/blood-2012-02-406090
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591171, KAKENHI-PROJECT-22659196, KAKENHI-PROJECT-23590299, KAKENHI-PROJECT-23591536, KAKENHI-PROJECT-23591537, KAKENHI-PROJECT-23591552, KAKENHI-PROJECT-23591560, KAKENHI-PROJECT-24390260, KAKENHI-PROJECT-24390268, KAKENHI-PROJECT-24591387, KAKENHI-PROJECT-24791054
[Journal Article] Absence of SHATI/Nat8l reduces social interaction in mice2012
- Author(s)
  Furukawa-Hibi, Y., Nitta, A., Furukawa, S., Nabeshima, T. and Yamada, K.(他3名)
- Journal Title
  
  Neurosci. Lett
  
  Volume: 526 Pages: 79-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Absence of SHATI/Nat8l reduces social interaction in mice.2012
- Author(s)
  Furukawa-Hibi Y, Nitta A, Fukumitsu H, Somiya H, Toriumi K, Furukawa S, Nabeshima T, Yamada K.
- Journal Title
  
  Neurosci Lett.
  
  Volume: 526 Issue: 2 Pages: 79-84
- DOI
  10.1016/j.neulet.2012.08.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659213, KAKENHI-PROJECT-23590299
[Journal Article] ストレスにより誘発される脳機能障害とストレス応答性転写因子Npas4の機能解析2012
- Author(s)
  永井拓, 尹在錫, 衣斐大祐, 小池宏幸, 日比陽子, 山田清文
- Journal Title
  
  日本薬理学雑誌
  
  Volume: 139 Pages: 147-151
- NAID
  10030572362
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Somatic mosaicism for oncogenic NRAS mutations in juvenile myelomonocytic leukemia2012
- Author(s)
  Doisaki, S., Muramatsu, H., Shimada, A., Furukawa-Hibi, Y., Yamada, K., Tanaka, M., Hama, A., Koike, K. and Kojima, S.(他16名)
- Journal Title
  
  Blood
  
  Volume: 120(7) Pages: 1485-1488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] 神経系におけるブチリルコリンエステラーゼの機能2012
- Author(s)
  日比陽子、山田清文
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 30 Pages: 672-674
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Using peripheral blood circulating DNAs to detect CpG global methylation status and genetic mutations in patients with myelodysplastic syndrome2012
- Author(s)
  Iriyama, C., Tomita, A., Furukawa-Hibi, Y., Yamada, K., Kiyoi, H., Naoe, T.(他2名)
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 419(4) Pages: 662-669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Using peripheral blood circulating DNAs to detect CpG global methylation status and genetic mutations in patients with myelodysplastic syndrome2012
- Author(s)
  Chisako Iriyama
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: (in press) Issue: 4 Pages: 662-669
- DOI
  10.1016/j.bbrc.2012.02.071
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591198, KAKENHI-PROJECT-23590299, KAKENHI-PROJECT-24591387
[Journal Article] 神経系におけるブチリルコリンエステラーゼの機能2012
- Author(s)
  日比陽子, 山田清文
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 30(6) Pages: 672-674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Butyrylcholinesterase inhibitors ameliorate cognitive dysfunction induced by amyloid-β peptide in mice.2011
- Author(s)
  Furukawa-Hibi, Y., Alkam T., Nitta, A., Matsuyama, A., Mizoguchi, H., Suzuki, K., Moussaoui, S., Yu, Q-S., Greig, N., Nagai, T. and Yamada, K.
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 225 Pages: 222-229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Periocular injection of in situ hydrogels containing Leu-Ile, an inducer for neurotrophic factors, promotes retinal ganglion cell survival after optic nerve injury2011
- Author(s)
  Nakatani, M., Shinohara, Y., Furukawa-Hibi, Y., Miyamoto, Y., Nitta, A.(他4名)
- Journal Title
  
  Experimental Eye Research
  
  Volume: 96(6) Pages: 873-879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] The hydrophobic dipeptide Leu-Ile inhibits immobility induced by repeated forced swimming via the induction of BDNF.2011
- Author(s)
  Furukawa-Hibi, Y., Nitta, A., Ikeda, T., Morishita, K., Liu W, Ibi D., Alkam, T., Nabeshima, T., and Yamada, K.
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 220 Pages: 271-280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Butrylcholinesterase inhibitors ameliorate cognitive dysfunction induced by amyloid-βpeptide in mice2011
- Author(s)
  Yoko Furukawa-Hibi, et al
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 225 Issue: 1 Pages: 222-229
- DOI
  10.1016/j.bbr.2011.07.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390046, KAKENHI-PROJECT-23659135
[Journal Article] Butyrylcholinesterase inhibitors ameliorate cognitive dysfunction induced by amyloid-βpeptide in mice2011
- Author(s)
  Furukawa-Hibi, Y., Alkam T., Nitta, A., Nagai, T. and Yamada, K.(他6名)
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 225 Pages: 222-229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] ストレスによる精神疾患の発症にDNAメチル化が関与する2011
- Author(s)
  日比陽子
- Journal Title
  
  ファルマシア
  
  Volume: 47(7) Pages: 663-664
- NAID
  110009900999
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] The hydrophobic dipeptide Leu-Ile inhibits immobility induced by repeated forced swimming via the induction of BDNF2011
- Author(s)
  Furukawa-Hibi, Y., Nitta, A., Ikeda, T., Nabeshima, T., and Yamada, K.(他4名)
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 220 Pages: 271-280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Over expression of Piccolo C2A domain induces depression-like behavior in mice.2010
- Author(s)
  Furukawa-Hibi Y, et al
- Journal Title
  
  NeuroReport.
  
  Volume: 21 Pages: 1177-1181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390045
[Journal Article] 脳由来神経栄養因子およびクリア細胞由来神経栄養因子と神経精神疾患との関係2009
- Author(s)
  日比陽子, 他
- Journal Title
  
  日本神経精神薬理学雑誌 29(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659292
[Patent] 抗らつ・抗不安剤2009
- Inventor(s)
  新田淳美, 日比陽子, 鍋島俊隆, 森下幸治, 池田武史
- Industrial Property Rights Holder
  協和発酵バイオ株式会社,国立大学法人名古屋大学
- Filing Date
  2009-01-23
- Overseas
- Data Source
  KAKENHI-PROJECT-19659292
[Patent] 意欲向上剤2009
- Inventor(s)
  新田淳美, 日比陽子, 池田武史, 酒井康
- Industrial Property Rights Holder
  協和発酵バイオ株式会社,国立大学法人名古屋大学
- Industrial Property Number
  2009-118772
- Filing Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-21390045
[Patent] 抗うつ・抗不安剤2009
- Inventor(s)
  新田淳美, 日比陽子, 鍋島俊隆, 森下幸治, 池田武史
- Industrial Property Rights Holder
  協和発酵バイオ株式会社,国立大学法人名古屋大学
- Filing Date
  2009-01-23
- Overseas
- Data Source
  KAKENHI-PROJECT-21390045
[Patent] 意欲向上剤2009
- Inventor(s)
  新田淳美, 日比陽子, 池田武史, 酒井康
- Industrial Property Rights Holder
  協和発酵バイオ株式会社,国立大学法人名古屋大学
- Industrial Property Number
  2009-118772
- Filing Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-19659292
[Presentation] バンコマイシンの初期投与設計における目標AUCと急性腎障害リスク因子の同定2023
- Author(s)
  飯田萌子, 堀田康弘, 朝岡みなみ, 村松桜子, 河原昌美, 堀田祐志, 中村敦, 日比陽子
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K11922
[Presentation] ベキサロテン関連高トリグリセリド血症の重症度に及ぼすBMIの影響：皮膚T細胞リンパ腫におけるベキサロテン＋光線療法のオープンラベル試験の事後解析2023
- Author(s)
  真川明将, 早川智章, 西田絵美, 山本礼, 井汲今日子, 森悠香梨, 堀田祐志, 木村和哲, 日比陽子, 森田明理
- Organizer
  医療薬学フォーラム2023／第31回クリニカルファーマシーシンポジウム
- Data Source
  KAKENHI-PROJECT-23K06257
[Presentation] Antifibrotic effects of tadalafil, a phosphodiesterase 5 inhibitor, with PAI1 downregulation via cGMP in rats and fibroblasts.2023
- Author(s)
  Noda M, Hotta Y, Naiki-Ito A, Tomita N, Sanagawa A, Kataoka T, Hibi Y, Takahashi S, Kimura K
- Organizer
  American Society of Nephrology Kidney Week 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06257
[Presentation] 「超少子・超高齢化を診る基礎編」精巣毒性について―抗がん化学療法と精子形成障害の今後―2023
- Author(s)
  片岡智哉, 堀田祐志, 真川明将, 日比陽子, 木村和哲
- Organizer
  日本アンドロロジー学会第42回学術大会
- Data Source
  KAKENHI-PROJECT-23K06257
[Presentation] バンコマイシンのAUC評価の臨床導入後の腎障害発現率と治療域達成率調査2023
- Author(s)
  加藤秀紀, 堀田康弘, 朝岡みなみ, 和知野千春, 飯田萌子, 三村佳久, 杉山洋介, 江崎哲夫, 堀田祐志, 日比陽子
- Organizer
  第33回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-23K11922
[Presentation] バンコマイシンの初期投与設計で腎障害を回避するための目標AUC2023
- Author(s)
  飯田萌子, 堀田康弘, 広瀬永愛, 朝岡みなみ, 木村理恵, 大橋一輝, 加藤秀紀, 江崎哲夫, 河原昌美, 堀田祐志, 中村敦, 日比陽子
- Organizer
  第33回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-23K11922
[Presentation] ラット腎線維芽細胞を用いたphosphodiesterase5阻害薬タダラフィルによる腎線維化抑制効果のメカニズムの検討2023
- Author(s)
  野田みすず, 冨田なつみ, 真川明将, 片岡智哉, 日比陽子, 堀田祐志, 木村和哲
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-23K06257
[Presentation] テイコプラニンのクリアランスに腎機能や体格が及ぼす影響2023
- Author(s)
  朝岡みなみ, 堀田康弘, 堀田祐志, 日比陽子
- Organizer
  第33回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-23K11922
[Presentation] Development and Evaluation of a Novel Software Program, SAKURA-TDM, for AUC-guided Vancomycin Dosing2023
- Author(s)
  Yasuhiro Horita, Yoko Hibi
- Organizer
  The 39th Annual Meeting for the Japanese Society of Therapeutic Drug Monitoring
- Invited
- Data Source
  KAKENHI-PROJECT-23K11922
[Presentation] ビンクリスチン投与に伴うEDモデルラットに対するDPP-4阻害薬オマリグリプチンの長期投与の効果2023
- Author(s)
  片岡智哉, 堀田祐志, 真川明将, 日比陽子, 木村和哲
- Organizer
  日本アンドロロジー学会第42回学術大会
- Data Source
  KAKENHI-PROJECT-23K06257
[Presentation] Transcriptional suppression of the neuronal PAS domain 4 (Npas4) gene by stress via glucocorticoid receptor in the brain2013
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, and Kiyofumi Yamada
- Organizer
  11th WFSBP
- Place of Presentation
  京都市　京都国際会議場
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Transcriptional suppression of the neuronal PAS domain 4 (Npas4) gene by stress via glucocorticoid receptor in the brain2013
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  11th WFSBP
- Place of Presentation
  京都府京都市京都国際会館
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] 脳特異的転写因子Npas4欠損マウスにおける異常行動とGABA作動性神経系マーカーの変化2013
- Author(s)
  日比(古川)陽子, 横井順平, 永井拓, 山田清文
- Organizer
  第123回日本薬理学会近畿部会
- Place of Presentation
  愛知県名古屋市愛知県産業労働センター
- Year and Date
  2013-07-12
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] グルココルチコイド受容体は神経分化関連因子NPAS4の転写を直接抑制するDirect transcriptional regulation of neuronal transcription factor Npas4 by glucocorticoid receptor2013
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  第86回日本薬理学会
- Place of Presentation
  福岡県博多市福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] グルココルチコイド受容体は神経分化関連因子NPAS4の転写を直接抑制する Direct transcriptional regulation of neuronal transcription factor Npas4 by glucocorticoid receptor2013
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, and Kiyofumi Yamada
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場（福岡）
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] 長期ストレスはGABA神経関連転写因子Npas4遺伝子のDNAメチル化を亢進する Chronic stress increases DNA methylation of Neuronal PAS domain 4 (Npas4)2013
- Author(s)
  日比（古川）　陽子、永井　拓、山田　清文
- Organizer
  第23回日本臨床精神神経薬理学会・第43回日本神経精神薬理学会合同年会
- Place of Presentation
  宜野湾市　沖縄コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] 長期ストレスはGABA神経関連転写因子Npas4遺伝子のDNAメチル化を亢進するChronic stress increases DNA methylation of Neuronal PAS domain 4 (Npas4)2013
- Author(s)
  日比(古川)陽子, 永井拓, 山田清文
- Organizer
  第23回日本臨床精神神経薬理学会・第43回日本神経精神薬理学会合同年会
- Place of Presentation
  沖縄県宜野湾市沖縄コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Glucocorticoid reduces the gene expression of neuronal PAS domain 4 (Npas4) in the brain2012
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, and Kiyofumi Yamada
- Organizer
  ASCB2012
- Place of Presentation
  サンフランシスコ　USA
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Glucocorticoid reduces the gene expression of neuronal PAS domain 4 (Npas4) in the brain2012
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  ASCB2012
- Place of Presentation
  USAサンフランシスコ
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Transcriptional regulation of neuronal PAS domain 4 (NPAS4) by glucocorticoid receptor2012
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  The 11th APSN,The 55th J SN(日本神経化学会)
- Place of Presentation
  兵庫県神戸市神戸国際会議場
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Stress regulates the gene expression of neuronal PAS domain 4 (Npas4), via glucocorticoid receptor2012
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  CINP 2012
- Place of Presentation
  スウェーデンストックホルム
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] グルココルチコイドによる転写因子NPAS4の発現抑制機構Glucocorticoid regulates the expression of neuronal PAS domain 4 (Npas4)2012
- Author(s)
  日比陽子, ユンジェスク, 永井拓, 山田清文
- Organizer
  第7回統合失調症学会
- Place of Presentation
  愛知県名古屋市愛知県産業労働センター
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Stress regulates the gene expression of neuronal PAS domain 4 (Npas4), via glucocorticoid receptor2012
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, and Kiyofumi Yamada
- Organizer
  CINP 2012
- Place of Presentation
  ストックホルム　スウェーデン
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Stress regulates the gene expression of neuronal transcription factor Npas4 via glucocorticoid2012
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, and Kiyofumi Yamada
- Organizer
  第４回GCOE国際シンポジウム
- Place of Presentation
  名古屋キャッスルホテル（愛知）
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] ブチリルコリンエステラーゼ阻害剤のアミロイドベータ誘発性認知機能障害改善効果Butyrylcholinesterase inhibitors ameliorate cognitive dysfunction induced by amyloid-β peptide in mice2012
- Author(s)
  日比(古川)陽子, アルカム・トルソン, 新田淳美, 松山明裕, 永井拓, 山田清文
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都府京都市京都国際会館
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Stress regulates the gene expression of neuronal transcription factor Npas4 via glucocorticoid2012
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  第4回GCOE国際シンポジウム
- Place of Presentation
  愛知県名古屋市ウエスティンナゴヤキャッスルホテル
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Transcriptional regulation of neuronal PAS domain 4 (NPAS4) by glucocorticoid receptor2012
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, and Kiyofumi Yamada
- Organizer
  The 11th APSN The 55th JSN（日本神経化学会）
- Place of Presentation
  神戸国際会議場（兵庫）
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] 神経発達関連転写因子NPAS4のストレスによる転写抑制機構の解明2011
- Author(s)
  日比(古川)陽子, ユンジェスク, 永井拓, 山田清文
- Organizer
  第119回日本薬理学会近畿部会
- Place of Presentation
  愛知県名古屋市愛知県産業労働センター
- Year and Date
  2011-07-08
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Stress reduces the expression of transcription factor, neuronal PAS domain 4 (NPAS4)2011
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  AsCNP2011
- Place of Presentation
  韓国ソウル市
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] ストレスによるneuronal PAS domain 4 (NPAS4)の転写制御Transcriptional regulation of neuronal PAS domain 4 (NPAS4) by stress2011
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  Neuroscience 2011
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] 神経発達関連転写因子NPAS4の発現調節機構の解明2011
- Author(s)
  日比(古川)陽子, ユンジェスク, 永井拓, 山田清文
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Acetylcholinesterase inhibitor reduces the tyrosine nitrarion induced by amyloid beta peptide2009
- Author(s)
  Hibi (Furukawa), ら
- Organizer
  第19回日本臨床精神神経薬理学会・第39回日本神経精神薬理学会合同年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19659292
[Presentation] 疎水性ジペプチドLui-lleの抗うつ薬としての可能性2009
- Author(s)
  日比陽子, ら
- Organizer
  第19回日本医療薬学会年会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-19659292
[Presentation] 疎水性ジペプチドLui-lleの抗うつ薬としての可能性2009
- Author(s)
  日比陽子, ら
- Organizer
  第19回日本医療薬学会年会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21390045
[Presentation] ジペプチドLeu-Ileによる抗うつ効果の解析2009
- Author(s)
  日比(古川)陽子, ら
- Organizer
  第115回日本薬理学会近畿部会
- Place of Presentation
  金沢
- Year and Date
  2009-06-26
- Data Source
  KAKENHI-PROJECT-21390045
[Presentation] Acetylcholinesterase inhibitor reduces the tyrosine nitrarion induced by amyloid beta peptide2009
- Author(s)
  Hibi (Furukawa), ら
- Organizer
  第19回日本臨床精神神経薬理学会・第39回日本神経精神薬理学会合同年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21390045
[Presentation] ジペプチドLeu-Ileによる抗うつ効果の解析.2009
- Author(s)
  日比(古川)陽子, ら
- Organizer
  第115回日本薬理学会近畿部会
- Place of Presentation
  金沢
- Year and Date
  2009-06-26
- Data Source
  KAKENHI-PROJECT-19659292
[Presentation] 神経発達関連転写因子NPAS4の発現調節機構の解明
- Author(s)
  日比（古川）陽子、ユン　ジェスク、永井　拓、山田　清文
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  国立京都国際会館・グランドプリンスホテル京都
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Transcription factor Npas4 regulates the sensory experience-dependent development of dendritic spines in newborn olfactory bulb interneurons.
- Author(s)
  吉原誠一、高橋弘雄、西村信城、木下雅仁、朝比奈諒、日比陽子、永井拓、山田清文、坪井昭夫
- Organizer
  第37回日本神経科学会大会
- Place of Presentation
  パシフィコ横浜　神奈川県横浜市
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-26460095
[Presentation] 脳特異的転写因子Npas4欠損マウスにおける異常行動とGABA作動性神経系マーカーの変化
- Author(s)
  日比（古川）　陽子、横井　順平、永井　拓、山田　清文
- Organizer
  第123回日本薬理学会近畿部会
- Place of Presentation
  名古屋市　ウインク愛知
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] グルココルチコイドによる転写因子NPAS4の発現抑制機構 Glucocorticoid regulates the expression of neuronal PAS domain 4 (Npas4).
- Author(s)
  日比　陽子、ユン　ジェスク、永井　拓、山田　清文
- Organizer
  第7回統合失調症学会
- Place of Presentation
  名古屋　愛知県産業労働センター
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Npas4 regulates neurite outgrowth and phosphoryation of synapsin I
- Author(s)
  Jaesuk Yun, Taku Nagai, Yoko Hibi, Keisuke Kuroda, Kozo Kaibuchi, Kiyofumi Yamada
- Organizer
  Neuroscience 2011
- Place of Presentation
  横浜　パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Transcription factor Npas4 regulates the sensory experience-dependent development of dendritic spines in newborn olfactory bulb interneurons.
- Author(s)
  吉原誠一、高橋弘雄、西村信城、木下雅仁、朝比奈諒、日比陽子、永井拓、山田清文、坪井昭夫
- Organizer
  第92回日本生理学会年会
- Place of Presentation
  神戸ポートピア　兵庫県神戸市
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-26460095
[Presentation] Transcription factor Npas4 regulates the sensory experience-dependent development of dendritic spines in newborn olfactory bulb interneurons.
- Author(s)
  吉原誠一、高橋弘雄、西村信城、木下雅仁、朝比奈諒、日比陽子、永井拓、山田清文、坪井昭夫
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜　神奈川県横浜市
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26460095
[Presentation] Methamphetamine-induced Npas4; possible role in neurite outgrowth and p-synapsin I expression
- Author(s)
  Yun Jaesuk, Nagai Taku, Hibi Yoko, Kuroda Keisuke, Kaibuchi Kozo,Yamada Kiyofumi
- Organizer
  平成23年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  名古屋　愛知県産業労働センター
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] 神経発達関連転写因子NPAS4のストレスによる転写抑制機構の解明
- Author(s)
  日比（古川）陽子、ユン　ジェスク、永井　拓、山田　清文
- Organizer
  第119回日本薬理学会近畿部会
- Place of Presentation
  名古屋　愛知県産業労働センター
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Transcriptional regulation of neuronal PAS domain 4 (NPAS4) by stress ストレスによるneuronal PAS domain 4 (NPAS4)の転写制御
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  Neuroscience 2011
- Place of Presentation
  横浜　パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] The Role of Npas4 in Neurite Outgrowth and phosphorylation of Synapsin I
- Author(s)
  Jaesuk Yun, Taku Nagai, Yoko Hibi, Keisuke Kuroda, Kozo Kaibuchi, Kiyofumi Yamada
- Organizer
  AsCNP
- Place of Presentation
  韓国　ソウル
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Stress reduces the expression of transcription factor, neuronal PAS domain 4 (NPAS4)
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai and Kiyofumi Yamada
- Organizer
  AsCNP
- Place of Presentation
  韓国　ソウル
- Data Source
  KAKENHI-PROJECT-23590299

1. 堀田祐志 (90637563)

# of Collaborated Projects: 6 results

# of Collaborated Products: 15 results
2. YAMADA Kiyofumi (30303639)

# of Collaborated Projects: 3 results

# of Collaborated Products: 48 results
3. 片岡智哉 (20737928)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
4. NAGAI Taku (10377426)

# of Collaborated Projects: 2 results

# of Collaborated Products: 39 results
5. 新田淳美 (20275093)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. 鍋島俊隆 (70076751)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. 堀田康弘 (80627539)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
8. 家田直弥 (00642026)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. MIZOGUCHI Hiroyuki (70402568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 村松慎一 (10239543)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 木村和哲 (00423848)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. 和知野千春 (90816563)

# of Collaborated Projects: 1 results

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13. 服部友紀 (90363936)

# of Collaborated Projects: 1 results

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14. 近藤勝弘 (00939770)

# of Collaborated Projects: 1 results

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15. 頭金正博 (00270629)

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16. 安部賀央里 (70440625)

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17. 伊藤穣 (80362482)

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18. 坪内希親 (70893311)

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19. 宮崎ゆか (50868297)

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20. 真川明将 (20827670)

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# of Collaborated Products: 7 results
21. 前田康博 (60275146)

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22. 川口充康 (10735682)

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23. 安井孝周 (40326153)

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24. 中川秀彦 (80281674)

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25. 三村佳久 (10839335)

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26. 中村敦 (40285200)

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27. 朝岡みなみ (70939628)

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# of Collaborated Products: 4 results
28. SOTOMATSU Manabu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. TORIUMI Kazuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. NAIKI Taku

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# of Collaborated Products: 1 results
31. TANAKA Tetsu

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# of Collaborated Products: 1 results
32. MIYAMOTO Yoshiaki

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# of Collaborated Products: 2 results
33. UNO Kyosuke

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34. 林泰秀

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35. 内木綾

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36. 高橋智

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37. 田中啓治

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38. 山森哲雄

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39. 田中真樹

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40. 田中謙二

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41. 阿部修

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42. 橋本亮太

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43. 森寿

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44. 吉原誠一

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45. 高橋弘雄

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Hibi Yoko 日比 陽子

HIBI Yoko 日比 陽子

日比 陽子 ヒビ ヨウコ

Research Projects

Research Products

Co-Researchers

Development of Data-Driven Predictive System by AI Aimed at Mitigating Risks of COVID-19 Long-Term Effects

Principal Investigator

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急性腎障害によるせん妄発症機構の解明～神経分化関連因子NPAS4を鍵としてPrincipal Investigator

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がん分子標的薬による腎障害の発現機序解明：BRAF阻害剤に着目した検討

Principal Investigator

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Light-based ED treatment - Development of light-responsive GC activator and application to the treatment of refractory ED

Principal Investigator

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Review Section

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Optimizing Therapeutic Indices of Antibiotics and Software Development for the Implementation of Dose Adjustment Based on Model-informed Precision Dosing

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Review Section

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Elucidation of the mechanism of delirium onset caused by dysfunction of the stress-sensitive factor NPAS4 and development of therapeutic drugsPrincipal Investigator

Principal Investigator

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Review Section

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Development of therapeutic agents for neuropsychiatric disorders targeting the stress-sensitive transcription factor NPAS4Principal Investigator

Principal Investigator

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Research Institution

Association of mental disorder and decrease of Npas4Principal Investigator

Principal Investigator

Project Period (FY)

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Role of neuronal PAS domain 4 (Npas4) in psychiatric disorder.Principal Investigator

Principal Investigator

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Functional analysis of IFITM3 in neurodevelopmental impairments

Principal Investigator

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神経・精神疾患に関与する新規分子の機能解明および臨床応用への可能性

Principal Investigator

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新規薬物依存タンパクshatiの生理機能解析

Principal Investigator

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Research Institution

[Book] 日本神経精神薬理学雑誌2009

Author(s)

Hibi Yoko 日比陽子

HIBI Yoko 日比陽子

日比陽子ヒビヨウコ