MURATA Takuya 村田卓也

… Alternative Names

村田卓也ムラタタクヤ

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Researcher Number	70305001
Other IDs
Affiliation (based on the past Project Information) *help	2013 – 2014: 独立行政法人理化学研究所, バイオリソースセンター, 開発研究員 2009 – 2012: 独立行政法人理化学研究所, 新規変異マウス研究開発チーム, 開発研究員 2003 – 2004: 独立行政法人理化学研究所, ボディプラン研究グループ, 研究員 2002: 理化学研究所, ボディプラン研究グループ, 研究員 2001: 理化学研究所, 発生・再生科学総合研究センター・ボディプラン研究グループ, 研究員 1998 – 1999: 熊本大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Laboratory animal science Except Principal Investigator Biological Sciences / Laboratory animal science / Biological Sciences
Keywords	Principal Investigator β-カテニン / 点突然変異マウス / マウス / ENU / Wnt / 内性器 / 疾患モデル / 不妊 Except Principal Investigator Emx / Emx1 … More / Otx / 脳領域化 / 頭部誘導 / ヘッドオーガナイザー / Emx2 / Otx2 / Cephalic neural crest cells / Corticogenesis / Forebrain / Midbrain / Antenior neuroectoderm / Head development / A-pax / 中枢神経堤細胞 / 0tx1 / 0tx2 / 中脳神経堤細胞 / ヤツメウナギ / ヘッドオ-ガナイザー / 0tx / 終脳形成 / 脳の部域化 / 原子内胚葉 / 頭部形態形成 / ノックアウトマウス / 原皮質 / 吻側神経外胚葉 / シスエレメント / 吻側原始内胚葉 / エピブラスト / 原始内胚葉 / 頭部神経堤細胞 / 皮質形成 / 前脳形成 / 中脳形成 / 原脳形成 / 前後軸形成 / 突然変異体 / 突然変異解析 / 疾患モデル / バイオインフォーマティクス / ゲノム解析 / 化学変異原 / 遺伝学 / マウス / DNAシーケンシング / 疾患モデル動物 / ENU / 量的遺伝 / 次世代シーケンシング / 突然変異 / ミュータジェネシス / ゲノム機能 / 逆遺伝学 / マウス遺伝学 / 新皮質形成 / 原皮質形成 / 間脳形成 / 2 / ロンボメアー1 / Otx1 / 変異マウス / 頭部形成 / 新規遺伝子 / 中脳 / 前脳 / 前後軸 / 脊椎動物の進化 / エンハンサー / Shisa / Pax6 Less

点突然変異アリル群からポストノックアウト時代の疾患モデルマウス開発を目指してPrincipal Investigator
- Principal Investigator
  
  村田卓也
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  The Institute of Physical and Chemical Research
High-throughput development of disease model mice by using next-generation technologies.
- Principal Investigator
  
  GONDO Yoichi
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  The Institute of Physical and Chemical Research
前脳形成の分子機構
- Principal Investigator
  
  SHINICHI Aizawa
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
  Kumamoto University
Genetic Analysis of head development in vertebrates
- Principal Investigator
  
  SHINICHI Aizawa
- Project Period (FY)
  1996 – 2000
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University

All 2014 2013 2012 2011 2010 2009 2004 Other

All Journal Article Presentation

[Journal Article] Defective craniofacial development and brain function in a mouse model for depletion of intracellular inositol synthesis2014
- Author(s)
  Ohnishi T, Murata T, Watanabe A, Hida A, Ohba H, Iwayama Y, Mishima K, Gondo Y, Yoshikawa T
- Journal Title
  
  J Biol Chem
  
  Volume: 289(15) Issue: 15 Pages: 10785-10796
- DOI
  10.1074/jbc.m113.536706
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390293, KAKENHI-ORGANIZER-24116001, KAKENHI-PLANNED-24116002, KAKENHI-PROJECT-24591737, KAKENHI-PROJECT-25241016, KAKENHI-PROJECT-25430100
[Journal Article] β-cateninC429S mice exibit sterility consequent to spatiotemporally sustained Wnt signalling in the internal genitalia.2014
- Author(s)
  Murata T, Ishitsuka Y, Karouji K, Kaneda H, Toki H, Nakai Y, Makino S, Fukumura R, Kotaki H, Wakana S, Noda T, Gondo Y
- Journal Title
  
  Scientific Reports
  
  Volume: 4 Issue: 1 Pages: 6959-6959
- DOI
  10.1038/srep06959
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25241016, KAKENHI-PROJECT-25430100, KAKENHI-PROJECT-25440096
[Journal Article] ouse Mutagenesis and Disease Models for Neuropsychiatric Disorders2011
- Author(s)
  Gondo, Y., Murata, T., Makino, S., Fukumura, R., Ishitsuka, Y
- Journal Title
  
  Curr Top Behav Neurosci [Epub ahead of print 2011 Feb 5]
  
  Volume: 7 Pages: 1-35
- DOI
  10.1007/7854_2010_106
- ISBN
  9783642197024, 9783642197031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21240043
[Journal Article] ENU-based gene-driven mutagenesis in the mouse: a next-generation gene-targeting system2010
- Author(s)
  Gondo Y, Fukumura R, Murata T, Makino S
- Journal Title
  
  Exp Anim
  
  Volume: 59(5) Pages: 537-48
- NAID
  130000419249
- Data Source
  KAKENHI-PROJECT-21240043
[Journal Article] Next-generation gene targeting in the mouse for functional genomics2009
- Author(s)
  Gondo, Y., Fukumura, R., Murata, T., Makino, S
- Journal Title
  
  BMB Reports
  
  Volume: 42(6) Pages: 315-323
- Data Source
  KAKENHI-PROJECT-21240043
[Journal Article] ang is a novel gene expressed in early neuroectoderm, but its null mutant exhibits no obvious phenotype.2004
- Author(s)
  Murata, T., et al.
- Journal Title
  
  Gene Expression Patterns 5
  
  Pages: 171-178
- Data Source
  KAKENHI-PROJECT-13138202
[Presentation] β-catenin^C429S mice cause infertility with spatiotemporally sustained Wnt signal in internal genitalia.2014
- Author(s)
  村田　卓也、権藤洋一
- Organizer
  変異マウス開発セミナー
- Place of Presentation
  神戸市　理化学研究所　発生再生科学総合研究センター動物資源開発室
- Invited
- Data Source
  KAKENHI-PROJECT-25430100
[Presentation] β-カテニン遺伝子にC429Sミスセンス不妊モデルマウス系統における生存力の検討2013
- Author(s)
  村田　卓也、石塚祐一、中井祐治、牧野茂、福村龍太郎、権藤洋一
- Organizer
  第60回日本実験動物学会総会
- Place of Presentation
  つくば市　つくば国際会議場
- Data Source
  KAKENHI-PROJECT-25430100
[Presentation] From monogenic to polygenic modeling of human diseases by mouse mutagenesis and next-generation sequencing (NGS)2013
- Author(s)
  Gondo Y, Fukumura R, Murata T, Makino S
- Organizer
  Joint Conference of Human Genome Meeting 2013 and 21st International Congress of Genetics. Singapore
- Place of Presentation
  Singapore
- Year and Date
  2013-04-16
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] Deep sequencing of mouse exome for modeling human diseases encompassing gene-to-gene interactions. Mouse Genetics 20112012
- Author(s)
  Gondo Y, Fukumura R, Murata T, Makino S
- Organizer
  Joint Conference of the IMGS, CTC, and GSA
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] Complex traits とENU mutagenesis; Reverse Genetics からForward へ2012
- Author(s)
  村田卓也, 福村龍太郎, 牧野茂, 権藤洋一
- Organizer
  平成24 年度国立遺伝学研究所研究会「マウスForward Genetics の新潮流:Common diseases(complex traits)のマウス遺伝学」
- Place of Presentation
  三島市招待講演
- Year and Date
  2012-12-07
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] Epithelial Organizations were defected during seminal vesicle and vaginal formation in a new Ctnnb1 infertile model mouse2012
- Author(s)
  Murata T, Toki H, Ishitsuka Y, Kaneda H, Makino S, Fukumura R, Wakana S, Noda T, Gondo Y
- Organizer
  The 26th International Mammalian Genome Conference (IMGC2012)
- Place of Presentation
  St. Pete Beach USA 口演採択演題
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] 単一遺伝子形質と量的形質のあいだをつなぐ新しい変異マウスライブラリーの開発と利用公開2012
- Author(s)
  権藤洋一,福村龍太郎,村田卓也,牧野茂
- Organizer
  日本遺伝学会第83回大会
- Place of Presentation
  京都, 日本
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] Evaluation of deep exome sequencing for the discovery of novel SNPs and de novo mutations by using the mouse model2012
- Author(s)
  Gondo Y, Fukumura R, Murata T, Makino S
- Organizer
  X-Gen Congress and Expo
- Place of Presentation
  San Diego, USA. March (Oxford Nanopore Poster Award 受賞)
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] beta-カテニンアミノ酸点突然変異マウスがもたらす不妊の分子メカニズムの解析を目指して2011
- Author(s)
  村田卓也, 他
- Organizer
  第25回モロシヌス研究会
- Place of Presentation
  新潟
- Year and Date
  2011-07-09
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] ベータカテニン遺伝子にアミノ酸置換点突然変異をもつ新しい不妊モデルマウス2011
- Author(s)
  村田卓也, 他
- Organizer
  第58回日本実験動物学会総会
- Place of Presentation
  東京
- Year and Date
  2011-05-25
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] An Amino-Acid-Substitution Mutation of the Beta-Catenin Gene Caused Transformation of Caudal Wollfian Duct to Seminal Vesicle of Males and Vaginal Atresia of Females in the Mouse2011
- Author(s)
  Murata T, et al
- Organizer
  The 44th Annual Meeting of the Society for the Study of Reproduction
- Place of Presentation
  Portland, USA
- Year and Date
  2011-07-31
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] Large-scale SAGE (serial analysis of gene expression) analysis by NGS (next generation sequencer) for quick molecular genotyping2011
- Author(s)
  Murata T, et al
- Organizer
  Mouse Genetics 2011, Joint Conference of the IMGS, CTC, and GSA
- Place of Presentation
  Washington DC, USA
- Year and Date
  2011-06-24
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] βカテニンC429Sアミノ酸置換点突然変異マウスからcanonical Wntシグナルの新しい機能を考える2011
- Author(s)
  村田卓也, 他
- Organizer
  日本発生生物学学会秋期シンポジウム2011
- Place of Presentation
  岡崎市
- Year and Date
  2011-12-20
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] 新しい不妊モデルマウスから$\beta-$カテニン遺伝子の機能を考える2011
- Author(s)
  村田卓也, 他
- Organizer
  日本遺伝学会第83回大会
- Place of Presentation
  京都
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] New sterile model mouse from RIKEN ENU-based gene-driven mutagenesis2010
- Author(s)
  Murata, T., Makino, S., Fukumura, R., Gondo, Y
- Organizer
  The 24th International Mammalian Genome Conference (IMGC2010)
- Place of Presentation
  Crete, Greece
- Year and Date
  2010-10-18
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] 次世代版ジーンターゲッティングシステムに基づく遺伝子間相互作用解明のためのモデルマウスリソース2010
- Author(s)
  権藤洋一、福村龍太郎、村田卓也、牧野茂
- Organizer
  日本遺伝学会第82回大会
- Place of Presentation
  札幌
- Year and Date
  2010-09-21
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] Gene-drivenミュータジェネシスから得られた新しい不妊モデルマウス2010
- Author(s)
  村田卓也, 他
- Organizer
  第24回モロシヌス研究会
- Place of Presentation
  熊本県南阿蘇村
- Year and Date
  2010-09-17
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] New sterile model mouse from RIKEN ENU-based gene-driven mutagenesis.2010
- Author(s)
  Murata, T., et al.
- Organizer
  The 24th International Mammalian Genome Conference (IMGC2010)
- Place of Presentation
  ギリシャクレタ
- Year and Date
  2010-10-18
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] Internal genitalia-specific defects and subsequent sterilities in the missense mutant mice on the β-catenin gene2010
- Author(s)
  Murata, T., et al.
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] Phenotype assessment of variable point mutant lines of the beta-catenin gene discovered by RGDMS (Riken ENU-based Gene-driven Mutagenesis System)2009
- Author(s)
  村田卓也
- Organizer
  The 23rd International Mammalian Genome Conference
- Place of Presentation
  La Jolla, USA
- Year and Date
  2009-11-03
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] Power of RIKEN gene-driven mouse mutagenesis and ENU mutant mouse library2009
- Author(s)
  村田卓也
- Organizer
  The 4th Asian Mouse Mutagenesis and Resource Association (AMMRA) Meeting
- Place of Presentation
  Kumamoto, Japan
- Year and Date
  2009-12-17
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] Application of two-dimensional NMR metabonomics to phenotyping of mutant mice using Nat1 I95T missense mutation mice as a model2009
- Author(s)
  村田卓也
- Organizer
  The 32nd Annual Meeting of the Molecular Biology Society of Japan
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] RIKEN ENU-based gene-driven mutagenesis system(RGDMS)を用いたβカテニン遺伝子点突然変異マウスの解析:I.ホモ接合個体に見られる遺伝的異常2009
- Author(s)
  村田卓也
- Organizer
  日本遺伝学会第81回大会
- Place of Presentation
  (信州大学)松本
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] Studies on Wnt and Shh pathway genes with multiple mutant alleles by RIKEN ENU-based gene-driven mutagenesis (RGDMS) in the mouse2009
- Author(s)
  村田卓也
- Organizer
  The 2nd International Conference on Functional Annotation of the Mammalian Genome (FANG 2009)
- Place of Presentation
  Banff, Canada
- Year and Date
  2009-04-25
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] The beta-catenin missense mutant mice show infertility, resulted from the malformed internal genitalia on both male and female2009
- Author(s)
  村田卓也
- Organizer
  Joint Cold Spring Harbor Laboratory/Wellcome Trust Conference Mouse Genetics & Genomics : Development Disease
- Place of Presentation
  Hinxton, UK
- Year and Date
  2009-09-04
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] ベータカテニンミスセンスマウスにおける内性器の形態異常にともなう不妊について2009
- Author(s)
  村田卓也
- Organizer
  第23回モロシヌス研究会
- Place of Presentation
  滋賀県守山
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] Functional genomics with next-generation gene-targeting2009
- Author(s)
  Gondo, Y., Fukumura, R., Murata, T., Makino, S. (2009)
- Organizer
  The 8th International Workshop on Advanced Genomics Expansion of Genome Science (AGW2009)
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] Caudal Wolffian duct with abnormally sustained Wnt/β-catenin signal prevents upper vaginal elongation, which causes vaginal atresia in the β-catenin C429S mouse
- Author(s)
  村田　卓也、他
- Organizer
  Forty-seventh Annual Meeting, Society for the Study of Reproduction
- Place of Presentation
  アメリカ合衆国　グランラピッズ市
- Year and Date
  2014-07-19 – 2014-07-22
- Data Source
  KAKENHI-PROJECT-25430100
[Presentation] Complex traitsとENU mutagenesis; Reverse GeneticsからForwardへ
- Author(s)
  村田卓也　他
- Organizer
  平成24年度国立遺伝学研究所研究会マウスForward Geneticsの新潮流 Common diseases（complex traits）のマウス遺伝学
- Place of Presentation
  三島市
- Invited
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] THE C429S MUTAION OF THE CTNNB1, WHICH ENCODES ESSENTIAL COMPONENT OF THE CANONICAL WNT SIGNALING, CAUSED THE INFERTILITIES WITH INTERNAL GENITAL MALFORMATIONS IN THE MOUSE
- Author(s)
  村田　卓也、他
- Organizer
  Human Genome Meeting 2014
- Place of Presentation
  スイス　ジュネーブ市
- Year and Date
  2014-04-27 – 2014-04-30
- Data Source
  KAKENHI-PROJECT-25430100
[Presentation] β-catenin C429Sアミノ酸置換点突然変異マウスに見られる精嚢上皮の異常
- Author(s)
  村田卓也　他
- Organizer
  第26回モロシヌス研究会
- Place of Presentation
  東京都文京区
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] Epithelial Organizations were defected during seminal vesicle and vaginal formation in a new \textit{Ctnnb1} infertile model mouse.
- Author(s)
  Murata T et al.
- Organizer
  26th International Mammalian Genome Conference
- Place of Presentation
  St. Pete Beach, USA
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] Wnt/β-catenin signalingの時空間特異的なファインチューニング：ENU点突然変異マウスの逆向き遺伝学より
- Author(s)
  村田卓也　他
- Organizer
  第9回異分野交流の夕べ
- Place of Presentation
  和光市
- Data Source
  KAKENHI-PROJECT-21240043
[Presentation] The mouse strain possessing the Cys429Ser base substitution of the β-catenin gene showed spatiotemporal sustainment of the canonical Wnt/ β-catenin signal during organogeneses of internal genitaria
- Author(s)
  村田　卓也、他
- Organizer
  EMBO Workshop on Wnt signalling
- Place of Presentation
  オーストラリア国　ブルーム市
- Year and Date
  2014-10-06 – 2014-10-09
- Data Source
  KAKENHI-PROJECT-25430100

1. SHINICHI Aizawa (60073011)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. GONDO Yoichi (40225678)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
3. FUKUMURA Ryutaro (90392240)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
4. MAKINO Shigeru (30462732)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
5. KIKUCHI Jun (00321753)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KAWAI Jun (30391923)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. AKIHITO Yamamoto (50244083)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. ISAO Matsuo (10264285)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 須田容子 (90201582)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 高崎延佳 (00342808)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 黒川大輔 (40342779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 木村淳 (70391935)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 植木龍也 (10274705)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 倉谷滋 (00178089)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. OHNISHI Tetsuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 吉川武男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MURATA Takuya 村田 卓也

村田 卓也 ムラタ タクヤ

Research Projects

Research Products

Co-Researchers

点突然変異アリル群からポストノックアウト時代の疾患モデルマウス開発を目指してPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

High-throughput development of disease model mice by using next-generation technologies.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

前脳形成の分子機構

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Genetic Analysis of head development in vertebrates

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Defective craniofacial development and brain function in a mouse model for depletion of intracellular inositol synthesis2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] β-cateninC429S mice exibit sterility consequent to spatiotemporally sustained Wnt signalling in the internal genitalia.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ouse Mutagenesis and Disease Models for Neuropsychiatric Disorders2011

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] ENU-based gene-driven mutagenesis in the mouse: a next-generation gene-targeting system2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Next-generation gene targeting in the mouse for functional genomics2009

Author(s)

Journal Title

Data Source

[Journal Article] ang is a novel gene expressed in early neuroectoderm, but its null mutant exhibits no obvious phenotype.2004

Author(s)

Journal Title

Data Source

[Presentation] β-catenin^C429S mice cause infertility with spatiotemporally sustained Wnt signal in internal genitalia.2014

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] β-カテニン遺伝子にC429Sミスセンス不妊モデルマウス系統における生存力の検討2013

Author(s)

Organizer

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[Presentation] From monogenic to polygenic modeling of human diseases by mouse mutagenesis and next-generation sequencing (NGS)2013

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[Presentation] Deep sequencing of mouse exome for modeling human diseases encompassing gene-to-gene interactions. Mouse Genetics 20112012

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[Presentation] Complex traits とENU mutagenesis; Reverse Genetics からForward へ2012

MURATA Takuya 村田卓也

村田卓也ムラタタクヤ