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Taniguchi Taizo  谷口 泰造

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TANIGUCHI Taizo  谷口 泰造

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Researcher Number 70346253
External Links
Affiliation (Current) 2025: 甲南大学, フロンティアサイエンス学部, 研究員
Affiliation (based on the past Project Information) *help 2018: 甲南大学, フロンティアサイエンス学部, 特別招聘研究員
2009 – 2017: 姫路獨協大学, 薬学部, 教授
2008: 姫路獨協大学, 薬学部, 客員教授
2007: Kobe University, Bio-signal Research Center, Lecturer
2003 – 2006: 神戸大学, バイオシグナル研究センター, 講師
Review Section/Research Field
Principal Investigator
Neuroscience in general / General pharmacology
Except Principal Investigator
Laboratory medicine / Physical pharmacy / Functional biochemistry / Tumor diagnostics / Experimental pathology / Neuroscience in general / Children studies (Studies of environment on children) / Biological pharmacy / Neuroscience in general
Keywords
Principal Investigator
Proteome analysis / Bioinformatics / Medicine / Brain and neural function / Behavioral analysis / Animal model of dementia / Dementia / 疾患モデル / プロテーム解析 / バイオインフォマティクス … More / 内科 / 脳・神経 / 行動学 / 疾患モデルマウス / 認知症 / 構造解析 / 膜蛋白 / 抗体療法 / 抗体 / 膜タンパク / DNA vaccination … More
Except Principal Investigator
タウ蛋白質 / NMR / ユビキチンープロテアソーム系 / プロテアソーム阻害剤 / ユビキチン-プロテアソーム系 / 肝細胞増殖因子 / アルツハイマー病 / ユビキチン化酵素 / M蛋白 / 多発性骨髄腫 / Alzheimer' disease inhibiting drug / self-aggregation / filament formation / microtubule-bindine domain / tau protein / 自己重合 / マイクロチュブル結合ドメイン / 微小管結合ドメイン / 認知症治療薬 / 自己会合 / フィラメント形成 / 微少管結合ドメイン / Ceramide / Lipid messenger / Fatty acid / C1 domain / Diacylglycerol kinase / Protein kinase C / DGK / PKC / セラミド / 脂質シグナル / 脂肪酸 / C1ドメイン / ジアシルグリセロールキナーゼ / プロテインキナーゼC / 癌診断 / バイオマーカー / ユビキチン / 診断 / がん / ARF / E2活性 / ユビキチンリガーゼ / がん診断 / ユビキチン化 / ユビキチン-プロテアソーム / ERストレス / PML/RARA / 幹細胞 / リゾリン脂質シグナル / 新規治療薬 / 神経再生誘導 / LPAシグナル / 治療 / 神経再生 / リゾリン脂質 / 神経幹細胞 / 認知症 / 学習記憶機能 / タウ蛋白 / タウオパチー / 活動性 / 苔状線維 / 大脳皮質層構築 / 海馬錐体細胞 / 恐怖条件付け / プレパルス抑制 / ADHDモデルラット / 発生学的異常 / 前頭前野 / メチルアゾキシメタノール / 発生学的形態異常 / 海馬 / 大脳皮質 / 多面的行動分析 / 注意欠陥多動性障害 / MAPキナーゼ / シコニン / TNF-α / 神経変性疾患 / 活性酸素 / 酸化ストレス / 炎症 / 抗酸化作用 / 創傷治癒 / 抗炎症作用 / 抗炎症剤 / パーキンソン病 / 神経生物学 / 長期増強現象 Less
  • Research Projects

    (12 results)
  • Research Products

    (81 results)
  • Co-Researchers

    (25 People)
  •  Evaluation of M-protein related ubiquitin enzyme as a new biomarker for Multiple Myeloma

    • Principal Investigator
      Mariko Takenokuchi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Himeji Dokkyo University
  •  Highly sensitive detection of ubiquitination using tumor-bearing mouse model

    • Principal Investigator
      Miyamoto Kazuhide
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor diagnostics
    • Research Institution
      Himeji Dokkyo University
  •  Analyses of lyzophosphatigic signaling for dementia and changing the signaling of neural stem cell for treatment

    • Principal Investigator
      CHIBA SHUNMEI
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Okinawa National College of Technology
      University of the Ryukyus
  •  Evaluation of serum ubiquitin enzyme as a new biomarker for PML-RARA leukemia

    • Principal Investigator
      Takenokuchi Mariko
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Himeji Dokkyo University
  •  Study on the therapeutic effects of hepatocyte growth factor on tauopathies using transgenic mice overexpressing mutated human tau.

    • Principal Investigator
      Keiichi KADOYAMA
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neuroscience in general
    • Research Institution
      Himeji Dokkyo University
  •  Developmental and neurobehavioral analyses of AD/HD model rats using multiple behavioral assessment

    • Principal Investigator
      SUGIOKA Kozo
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Children studies (Studies of environment on children)
    • Research Institution
      Himeji Dokkyo University
  •  Prevention and treatment of neurodegenerative diseases(Alzheimer's disease and Parkinson's disease) via inhibition of Syk kinase.

    • Principal Investigator
      OHMURO Hiromi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Musashino University
  •  Analysis for the therapeutic effect of hepatocyte factor on learning and memory dysfunction in the mouse model of Alzheimer's Disease.

    • Principal Investigator
      KADOYAMA Keiichi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neuroscience in general
    • Research Institution
      Himeji Dokkyo University
  •  Analysis of brain disfunction and behavioral abnormality using the dementia or depression model micePrincipal Investigator

    • Principal Investigator
      TANIGUCHI Taizo
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neuroscience in general
    • Research Institution
      Kobe University
  •  Elucidation of Self-aggregation Mechanism of Tau Protein : Basic Research for Drug Development of Inhibiting Alzheimer's disease

    • Principal Investigator
      ISHIDA Toshimasa
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Osaka University of Pharmaceutical Sciences
  •  DNA Vaccinationによる膜機能蛋白に対する抗体作成Principal Investigator

    • Principal Investigator
      谷口 泰造
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General pharmacology
    • Research Institution
      Kobe University
  •  Analysis of higher structure of fatty aid -responsible domains in PKC and DGK

    • Principal Investigator
      SHIRAI Yasuhito
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Kobe University

All 2018 2016 2015 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004

All Journal Article Presentation

  • [Journal Article] Evaluation of Absorbability of Macromolecular Substances in the Oral Mucosa and Skin using a Three-Dimensional Tissue Culture Model2018

    • Author(s)
      Takenokuchi Mariko、Kadoyama Keiichi、Yoshida Daisuke、Takaki Shigeki、Yamamoto Ryoma、Saigo Katsuyasu、Taniguchi Taizo
    • Journal Title

      Biology and Medicine

      Volume: 10 Issue: 5 Pages: 1-9

    • DOI

      10.4172/0974-8369.1000448

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08983
  • [Journal Article] Improved isolation procedure for shikonin from the root of the Chinese medicinal plant Lithospermum erythrorhizon and its solubilization with cyclodextrins2016

    • Author(s)
      Hideki Azuma, Jiawei Li, Ryota Youda, Toshio Suzuki, Kazuhide Miyamoto, Taizo Taniguchi, Takeshi Nagasaki
    • Journal Title

      J. Appl. Res. Med. Arom Plants

      Volume: 3 Issue: 2 Pages: 58-63

    • DOI

      10.1016/j.jarmap.2016.01.002

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26350528, KAKENHI-PROJECT-26430147
  • [Journal Article] Bortezomib Causes ER Stress-related Death of Acute Promyelocytic Leukemia Cells Through Excessive Accumulation of PML-RARA2015

    • Author(s)
      Mariko Takenokuchi, Kazuhide Miyamoto, Katsuyasu Saigo, Taizo Taniguchi
    • Journal Title

      ANTICANCER RESEARCH

      Volume: 35(6) Pages: 3307-3316

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25460711
  • [Journal Article] Esophageal cancer exhibits resistance to a novel IGF-1R inhibitor NVP-AEW541 with maintained RAS-MAPK activity.2012

    • Author(s)
      Bao, X.H
    • Journal Title

      Anticancer Res

      Volume: 32 Issue: 3 Pages: 2827-2834

    • DOI

      10.1159/000218708

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390323, KAKENHI-PROJECT-25460711
  • [Journal Article] Hepatocyte growth factor overexpression in the nervous system enhances learning and memory performance in mice2012

    • Author(s)
      Kato T, Funakoshi H, Kadoyama K, Noma S, Kanai M, Ohya-Shimada W, Mizuno S, Doe N, Taniguchi T, Nakamura T
    • Journal Title

      J. Neurosci. Res

      Volume: 90(9) Issue: 9 Pages: 1743-55

    • DOI

      10.1002/jnr.23065

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590362, KAKENHI-PROJECT-23590458, KAKENHI-PROJECT-24500389, KAKENHI-PROJECT-24730636
  • [Journal Article] Loss of dopaminoreceptive neuron causes L-dopa resistant Parkinsonism in tauopathy.2012

    • Author(s)
      Shunmei Chiba, Erika Takada, Mamoru Tadokoro, Taizo Taniguchi, Keiichi Kadoyama, Mariko Takenokuchi, Seiya Kato, Noboru Suzuki
    • Journal Title

      Neurobiology of Aging

      Volume: 33 (10) Issue: 10 Pages: 2491-2505

    • DOI

      10.1016/j.neurobiolaging.2011.11.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24500389
  • [Journal Article] Reaction of shikonin with superoxide anion2012

    • Author(s)
      Lucia S.Yoshida, Shunji Kohri, Hirotada Fujii, Shohko Tsunawaki, Taizo Taniguchi, Hiromi Takano-Ohmuro
    • Journal Title

      J.Pharmacol.Sci.

      Volume: 118巻 Pages: 256-256

    • Data Source
      KAKENHI-PROJECT-21590106
  • [Journal Article] Synaptotagmin1 synthesis induced by synaptic plasticity in mouse hippocampus through activation of nicotinic acetylcholine receptors.2011

    • Author(s)
      Takaaki Nishimoto, Keiichi Kadoyama, Taizo Taniguchi, Masaoki Takano, Mieko Otani, Tooru Nakamura-Hirota, Yabin Lu, Akira Matsumoto, Shogo Matsuyama, (equally contribution)
    • Journal Title

      Neuroscience Letters

      Volume: 489(1) Pages: 25-29

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Journal Article] Synaptotagmin1 synthesis induced by synaptic plasticity in mouse hippocampus through activation of nicotinic acetylcholine receptors.2011

    • Author(s)
      Nishimoto T, Kadoyama K, Taniguchi T, Takano M, Otani M, Nakamura-Hirota T, Lu Y, Matsumoto A, Matsuyama S
    • Journal Title

      Neurosci.Lett. 489

      Pages: 25-29

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Journal Article] Phosphoproteome profiling using a fluorescent phosphosensor dye in two-dimensional polyacrylamide gel electrophoresis.2011

    • Author(s)
      Otani M, Taniguchi T, Sakai A, Seta J, Kadoyama K, Nakamura-Hirota T, Matsuyama S, Sano K, Takano M
    • Journal Title

      Appl.Biochem.Biotechnol. 164

      Pages: 804-18

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Journal Article] SJLB mice develop tauopathy-induced parkinsonism.2010

    • Author(s)
      Takenokuchi M, Kadoyama K, Chiba S, Sumida M, Matsuyama S, Saigo K, Taniguchi T
    • Journal Title

      Neurosci.Lett. 473

      Pages: 182-185

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Journal Article] SJLB mice develop tauopathy-induced parkinsonism.2010

    • Author(s)
      Mariko Takenokuchia, Keiichi Kadoyama, Shunmei Chiba, Miho Sumida, Shogo Matsuyama, Katsuyasu Saigo, Taizo Taniguchi
    • Journal Title

      Neuroscience Letters 473

      Pages: 182-185

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Journal Article] Use of a phosphosensor dye in proteomic analysis of human mutant tau transgenic mice.2009

    • Author(s)
      Masaoki Takano, Mieko Otani, Akiko Sakai, Keiichi Kadoyama, Shogo Matsuyama, Akira Matsumoto, Mariko Takenokuchi, MihoSumida, Taizo Taniguchi
    • Journal Title

      NeuroReport 20

      Pages: 1648-1653

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Journal Article] Use of a phosphosensor dye in proteomic analysis of human mutant tau transgenic mice.2009

    • Author(s)
      Takano M, Otani M, Sakai A, Kadoyama K, Matsuyama S, Matsumoto A, Takenokuchi M, Sumida M, Taniguchi T
    • Journal Title

      NeuroReport 20

      Pages: 1648-1653

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Journal Article] GABA_A受容体アンタゴニストによるLTP様疎通の誘発2009

    • Author(s)
      松山正剛、角山圭一、谷口泰造
    • Journal Title

      生体の科学 60

      Pages: 392-393

    • Data Source
      KAKENHI-PROJECT-20500295
  • [Journal Article] Long-term potentiation-like facilitation through GABA_A receptor blockade in the mouse dentate gyrus in vivo.2008

    • Author(s)
      Matsuyama S, Taniguchi T, Kadoyama K, Matsumoto A
    • Journal Title

      NeuroReport 19

      Pages: 1809-1813

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Journal Article] Linkage-dependent contribution of repeat peptides to self-aggregation of three- or four-repeat microtubule-binding domains in tau protein2008

    • Author(s)
      Okuyama, K, Nishiura, C, Mizushima, F, Minoura, K, Sumida, M, Taniguchi, T, Tomoo, K, Ishida, T
    • Journal Title

      FEBS J 275(7)

      Pages: 1529-39

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18500242
  • [Journal Article] Long-term potentiation-like facilitation through GABA_A receptor blockade in the mouse dentate gyrus in vivo.2008

    • Author(s)
      Shogo Matsuyama, Taizo Taniguchi, Keiichi Kadoyama, Akira Matsumoto
    • Journal Title

      NeuroReport 19

      Pages: 1809-1813

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Journal Article] Marked difference between self-aggregations of first and fourth repeat peptides on tau microtubule-binding domain in acidic solution2007

    • Author(s)
      Mizushima, F, Minoura, K, Tomoo, K, Sumida, M, Taniguchi, T, Ishida, T
    • Journal Title

      J Biochem 142(1)

      Pages: 49-54

    • NAID

      10020097851

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18500242
  • [Journal Article] Marked difference between self-aggregations of first and fourth repeat peptides on microtubule-binding domain in acidic solution2007

    • Author(s)
      F. Mizushima, K. Minoura, K. Tomoo, M. Sumida, T. Taniguchi, T. Ishida
    • Journal Title

      J. Biochem. 142

      Pages: 49-54

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590045
  • [Journal Article] Marked difference between self-aggregations of first and fourth repeat peptides on tau microtubule-binding domain in acidic solution2007

    • Author(s)
      F.Mizushima, K.Minoura, K.Tomoo, M.Sumida, T.Taniguchi, T.Ishida
    • Journal Title

      J.Biochem 142

      Pages: 49-54

    • NAID

      10020097851

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590045
  • [Journal Article] Episodes behind developing the dementia model mice SJLB2006

    • Author(s)
      Taniguchi, T
    • Journal Title

      LABIO 21.26

      Pages: 25-29

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18500242
  • [Journal Article] N-Terminal secondary structures of second and third repeat fragment responsible for self-assembly of tau microtubule-binding domain2006

    • Author(s)
      K.Minoura, M Tokimasa, S Hiraoka, F Mizushima, K Tomoo, M Sumida, T Taniguchi, T Ishida
    • Journal Title

      Peptide Sciences 2005

      Pages: 367-370

    • NAID

      10017675968

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590045
  • [Journal Article] 認知症(痴呆)モデルマウスSJLB開発のエピソード2006

    • Author(s)
      谷口 泰造
    • Journal Title

      LABIO 21 26

      Pages: 25-29

    • Data Source
      KAKENHI-PROJECT-18500242
  • [Journal Article] Fluorescence-coupled CD conformational monitoring of filament formation of tau microtubule-binding repeat domain2006

    • Author(s)
      F.Mizushima, K.Minoura, K.Tomoo, M.Sumida, T.Taniguchi, T.Ishida
    • Journal Title

      Biochem. Biophys. Res. Commun. 343

      Pages: 712-718

    • Data Source
      KAKENHI-PROJECT-17590045
  • [Journal Article] N-Terminal secondary structures of second and third repeat fragment responsible for self-assembly of tau microtubule-binding domain2006

    • Author(s)
      Katsuhiko Minoura, Man Tokimasa, Shuko Hiraoka, Fumie Mizushima, Koji Tomoo, Miho Sumida, Taizo Taniguchi, Toshimasa Ishida
    • Journal Title

      Peptide Sciences 2005

      Pages: 367-370

    • NAID

      10017675968

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590045
  • [Journal Article] N-Terminal secondary structures of second and third repeat fragment responsible for self-assembly of tau microtubule-binding domain2006

    • Author(s)
      K.Minoura, M.Tokimasa, S.Hiraoka, F.Mizushima, K.Tomoo, M.Sumida, T.Taniguchi, T.Ishida
    • Journal Title

      Peptide Science 2005

      Pages: 367-370

    • NAID

      10017675968

    • Data Source
      KAKENHI-PROJECT-17590045
  • [Journal Article] PH-dependent filament formation of repeat peptide of microtubule-binding domain of tau protein2006

    • Author(s)
      F.Mizushima, K.Minoura, K.Tomoo, S.Hiraoka, M.Sumida, T.Taniguchi, T.Ishida
    • Journal Title

      Peptide Science 2005

      Pages: 305-308

    • NAID

      10017675852

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590045
  • [Journal Article] Fluorescence-coupled CD conformational monitoring of filament formation of tau microtubule-binding repeat domain2006

    • Author(s)
      F.Mizushima, K.Minoura, K.Tomoo, M.Sumida, T.Taniguchi, T.Ishida
    • Journal Title

      Biochem.Biophys.Res.Commun 343

      Pages: 712-718

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590045
  • [Journal Article] Fluorescence-coupled CD conformational monitoring of filament formation of tau microtubule-binding repeat domain2006

    • Author(s)
      Mizushima, F, Minoura, K, Tomoo, K, Sumida, M, Taniguchi, T, Ishida, T
    • Journal Title

      Biochem. Biophys. Res. Commun 327

      Pages: 712-718

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18500242
  • [Journal Article] Fluorescence-coupled CD conformational monitoring of filament formation of tau microtubule-binding repeat domain2006

    • Author(s)
      F. Mizushima, K.Minoura, K. Tomoo, M. Sumida, T. Taniguchi, T. Ishida
    • Journal Title

      Biochem. Biophys. Res. Commun. 343

      Pages: 712-718

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590045
  • [Journal Article] PH-dependent filament formation of repeat peptide of microtubule-binding domain of tau protein2006

    • Author(s)
      F. Mizushima, K. Minoura, K. Tomoo, S. Hiraoka, M. Sumida, T. Taniguchi, T. Ishida
    • Journal Title

      Peptide Science 2005

      Pages: 305-308

    • NAID

      10017675852

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590045
  • [Journal Article] 認知症(痴呆)モデルマウスSJLB開発のエピソード2006

    • Author(s)
      谷口 泰造
    • Journal Title

      LABIO21 26

      Pages: 25-29

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18500242
  • [Journal Article] Structural evaluation of conformational transition state responsible for self-assembly of tau microtubule-binding domain2005

    • Author(s)
      K.Minoura, F.Mizushima, M.Tokimasa, S.Hiraoka, K.Tomoo, M.Sumida, T.Taniguchi, T.Ishida
    • Journal Title

      Biochem.Biophys.Res.Commun. 327

      Pages: 1100-1104

    • Data Source
      KAKENHI-PROJECT-17590045
  • [Journal Article] Effects of different anti-tau antibodies on tau fibrillogenesis: RTA-1 and RTA-2 counteract tau aggregation2005

    • Author(s)
      T. Taniguchi, M. Sumida, S. Hiraoka, K.Tomoo, T. Kakehi, K.Minoura, S. Sugiyama, K.Inaka, T. Ishida, N. Saito, C. Tanaka
    • Journal Title

      FEBS Lett. 579

      Pages: 1399-1404

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590045
  • [Journal Article] Structural evaluation of conformational transition state responsible for self-assembly of tau microtubule-binding domain.2005

    • Author(s)
      Minoura, K., Mizushima, F., Tokimasa, M., Hiraoka, S., Tomoo, K., Sumida, M., Taniguchi, T., Ishida, T.
    • Journal Title

      Biochem Biophys Res Commun 327

      Pages: 1100-1104

    • Data Source
      KAKENHI-PROJECT-16659065
  • [Journal Article] Solvent-dependent conformational change of third repeat fragment of microtubule-binding domain responsible for filament formation of tauprotein2005

    • Author(s)
      K.Minoura, F.Mizushima, M.Tokimasa, S.Hiraoka, K.Tomoo, M.Sumida, T.Taniguchi, T.Ishida
    • Journal Title

      Peptide Science 2004

      Pages: 545-548

    • NAID

      10014460563

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590045
  • [Journal Article] Structural evaluation of conformational transition state responsible for self-assembly of tau microtubule-binding domair2005

    • Author(s)
      K. Minoura, F. Mizushima, M. Tokimasa, S. Hiraoka, K. Tomoo, M. Sumida, T. Taniguchi, T. Ishida
    • Journal Title

      Biochem. Biophys. Res. Commun. 327

      Pages: 1100-1104

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590045
  • [Journal Article] Possible role of each repeat strucutre of the microtubule-binding domain of the tau protein in in vitro aggregation2005

    • Author(s)
      K.Tomoo, T.-M.Yao, K.Minoura, S.Hiraoka, M.Sumida, T.Taniguchi, T.Ishida
    • Journal Title

      J.Biochem 138

      Pages: 413-423

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590045
  • [Journal Article] Effects of different anti-tau antibodies on tau fibrillogenesis : RTA-1 and RTA-2 counteract tau aggregation.2005

    • Author(s)
      Taniguchi, T., Sumida, M., Hiraoka, S., Tomoo, K., Kakehi, T., Minoura, K., Sugiyama, S., Inaka, K., Ishida, T., Saito, N., Tanaka, C.
    • Journal Title

      FEBS Letters 579

      Pages: 1399-1404

    • Data Source
      KAKENHI-PROJECT-16659065
  • [Journal Article] Importance of local structures of second and thirs repeat fragments of microtubule-binding domain for tau filament formation2005

    • Author(s)
      M.Tokimasa, K.Minoura, S.Hiraoka, K.Tomoo, Sumida, T.Taniguchi, T.Ishida
    • Journal Title

      FEBS Lett. 579

      Pages: 3481-3486

    • Data Source
      KAKENHI-PROJECT-17590045
  • [Journal Article] Solvent-dependent conformarional change of third repeat fragment of microtubule-binding domain responsible for filament formation of tau protein2005

    • Author(s)
      K.Minoura, F.Mizushima, M.Tokimasa, S.Hiraoka, K.Tomoo, M.Sumida, T.Taniguchi, T.Ishida
    • Journal Title

      Protein Science 2004

      Pages: 545-548

    • Data Source
      KAKENHI-PROJECT-17590045
  • [Journal Article] Importance of local structures of second and thirs repeat fragments of microtubule-binding domain for tau filament formation2005

    • Author(s)
      M. Tokimasa, K. Minoura, S. Hiraoka, K. Tomoo, M. Sumida, T. Taniguchi, T. Ishida
    • Journal Title

      FEBS Lett. 579

      Pages: 3481-3486

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590045
  • [Journal Article] Possible role of each repeat strucutre of the microtubule-binding domain of the tau protein in in vitro aggregation2005

    • Author(s)
      K. Tomoo, T.-M. Yao, K. Minoura, S. Hiraoka, M. Sumida, T. Taniguchi, T. Ishida
    • Journal Title

      J. Biochem. 138

      Pages: 413-423

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590045
  • [Journal Article] Solvent-dependent conformational change of third repeat fragment of microtubule-binding domain responsible for fliament formation of tau protein.2005

    • Author(s)
      K. Minoura, F. Mizushirna, M. Tokimasa, S. Hiraoka, K. Tomoo, M. Sumida, T. Taniguchi, T. Ishida
    • Journal Title

      Peptide Science 2004

      Pages: 545-548

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590045
  • [Journal Article] Structural evaluation of conformational transition state responsible for self-assembly of tau microtubule-binding domain2005

    • Author(s)
      K.Minoura, F.Mizushima, M.Tokimasa, S.Hiraoka, K.Tomoo, M.Sumida, T.Taniguchi, T.Ishida
    • Journal Title

      Biochem.Biophys.Res.Commun 327

      Pages: 1100-1104

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590045
  • [Journal Article] Possible role of each repeat strcuutre of the microtubule-binding domain of the tau protein in in vitro aggregation2005

    • Author(s)
      K.Tomoo, T.M.Yao, K.Minoura, S.Hiraoka, M.Sumida, T.Taniguchi, T.Ishida
    • Journal Title

      J.Biochem. 138

      Pages: 413-423

    • Data Source
      KAKENHI-PROJECT-17590045
  • [Journal Article] Importance of local structures of second and thirs repeat fragments of microtubule-binding domain for tau filament formation2005

    • Author(s)
      M.Tokimasa, K.Minoura, S.Hiraoka, K.Tomoo, M.Sumida, T.Taniguchi, T.Ishida
    • Journal Title

      FEBS Lett. 579

      Pages: 3481-3486

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590045
  • [Journal Article] Effects of different anti-tau antibodies on tau fibrillogenesis:RTA-1 and RTA-2 counteract tau aggregation2005

    • Author(s)
      T.Taniguchi, M.Sumida, S.Hiraoka, K.Tomoo, T.Kakehi, K.Minoura, S.Sugiyama, K.Inaka, T.Ishida, N.Saito, C.Tanaka
    • Journal Title

      FEBS Lett. 579

      Pages: 1399-1404

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590045
  • [Journal Article] Effects of different anti-tau antibodies on tau fibrillogenesis : RTA-1 and RTA-2 counteract tau aggregation2005

    • Author(s)
      T.Taniguchi, M.Sumida, S.Hiraoka, K.Tomoo, T.Kakehi, K.Minoura, S.Sugiyama, K.Inaka, T.Ishida, N.Saito, C.Tanaka
    • Journal Title

      FEBS Lett 579

      Pages: 1399-1404

    • Data Source
      KAKENHI-PROJECT-17590045
  • [Journal Article] Activation and translocation of PKCδ is necessary for VEGF-induced ERK activation through KDR in HEK293T cells2004

    • Author(s)
      Kuriyama M, Taniguchi T, Shirai Y, Sasaki A, Yoshimura A, Saito N
    • Journal Title

      Biochem.Biophys.Res.Comm. 325

      Pages: 843-851

    • Data Source
      KAKENHI-PROJECT-15570115
  • [Journal Article] Conformational transition state is responsible for assembly of microtubule-binding domain of tau protein.2004

    • Author(s)
      Hiraoka S, Yao TM, Minoura K, Tomoo K, Sumida M, TaniguchiT, Ishida T.
    • Journal Title

      Biochem Biophys Res Commun 315

      Pages: 659-663

    • Data Source
      KAKENHI-PROJECT-16659065
  • [Journal Article] Different associational and conformational behaviors between the second and third repeat fragments in the tau microtubule-binding domain.2004

    • Author(s)
      Minoura K, Yao TM, Tomoo K, Sumida M, Sasaki M, Taniguchi T, Ishida T.
    • Journal Title

      Eur J Biochem 271

      Pages: 545-552

    • Data Source
      KAKENHI-PROJECT-16659065
  • [Journal Article] Activation and translocation of PKCdelta is necessary for VEGF-induced ERK activation through KDR in HEK293T cells.2004

    • Author(s)
      Kuriyama, M., Taniguchi, T., Shirai, Y., Sasaki, A., Yoshimura, A., Saito, N.
    • Journal Title

      Biochem Biophys Res Commun 325

      Pages: 843-851

    • Data Source
      KAKENHI-PROJECT-16659065
  • [Presentation] 抗炎症及び抗酸化作用を有する生薬成分シコニンの神経変性疾患(アルツハイマー病及びパーキンソン病)治療への応用-モデル動物を用いた検討2013

    • Author(s)
      谷口 泰造、吉田ルシア 幸子、七里 博章、渡邊 愛未、炬口 真理子、角山 圭一、宮本 和英、大室 弘美
    • Organizer
      第86回 日本薬理学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24500389
  • [Presentation] アレルギー性皮膚炎の治療薬シコニンの効果2012

    • Author(s)
      渡邉愛未、七里博章、炬口真理子、角山圭一、宮本和英、中村隆典、高橋尚士、大室弘美、岩崎利郎、谷口泰造
    • Organizer
      日本獣医内科学アカデミー/日本獣医臨床病理学会2012年大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2012-02-17
    • Data Source
      KAKENHI-PROJECT-21590106
  • [Presentation] 炎症作用を有する生薬成分シコニンのスーパーオキシド消去作用2012

    • Author(s)
      吉田ルシア幸子、郡俊志、藤井博匡、綱脇祥子、谷口泰造、大室弘美
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2012-03-16
    • Data Source
      KAKENHI-PROJECT-21590106
  • [Presentation] アレルギー性皮膚炎の治療薬-シコニンの効果-2012

    • Author(s)
      渡邉愛未、七里博章、炬口真理子、角山圭一、宮本和英、中村隆典、高橋尚士、大室弘美、岩崎利郎、谷口泰造
    • Organizer
      日本獣医内科学アカデミー/日本獣医臨床病理学会2012年大会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2012-02-17
    • Data Source
      KAKENHI-PROJECT-21590106
  • [Presentation] 抗炎症作用を有する生薬成分シコニンのスーパーオキシド消去作用2012

    • Author(s)
      吉田ルシア幸子、郡俊志、藤井博匡、綱脇祥子、谷口泰造、大室弘美
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都(国立京都国際会館)
    • Year and Date
      2012-03-16
    • Data Source
      KAKENHI-PROJECT-21590106
  • [Presentation] 認知症モデルマウスにおける移植治療への検討2010

    • Author(s)
      千葉俊明、高田えりか、樋山梢、谷口泰造、角山圭一、田所衛、鈴木登
    • Organizer
      第9回日本再生医療学会総会
    • Place of Presentation
      広島国際会議場(広島県)
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Presentation] 認知症モデルマウスにおける移植治療への検討2010

    • Author(s)
      千葉俊明、高田えりか、樋山梢、谷口泰造、角山圭一、田所衛、鈴木登
    • Organizer
      第9回日本再生医療学会総会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Presentation] SJLBマウスとAPP変異マトランスジェニックマウスにおける リン酸化プロテオーム解析2009

    • Author(s)
      鷹野正興、尾谷三枝子、富山貴美、森啓、谷口泰造、角山圭一、松山正剛
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Presentation] Parkinsonism induced by tauopathy : Analysis of SJLB mice.2009

    • Author(s)
      Taniguchi T, Kadoyama K, Takenokuchi M, Chiba S, Suzuki N, Matsumoto A, Matsuyama S
    • Organizer
      The 22nd Biennial Meeting of the ISN/APSN Joint Meeting
    • Place of Presentation
      Busan, Korea
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Presentation] Parkinsonism induced by tauopathy : Analysis of SJLB mice.2009

    • Author(s)
      Taizo Taniguchi, Keiichi Kadoyama, Mariko Takenokuchi, Shunmei Chiba, Noboru Suzuki, Akira Matsumoto, Shogo Matsuyama
    • Organizer
      The 22nd Biennial Meeting of the ISN/APSN Joint Meeting
    • Place of Presentation
      BEXCO, Busan, KOREA
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Presentation] マウス脳内synaptotagminlの発現に対するニコチンの影響2009

    • Author(s)
      西本高明, 角山圭一, 谷口泰造, 松本明, 松山正剛
    • Organizer
      第82回日本薬理学会・年会
    • Place of Presentation
      パシフイコ横浜
    • Year and Date
      2009-03-16
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Presentation] Phosphoproteome profiling of human tau with N279K mutation transgenic mice.2009

    • Author(s)
      Masaoki Takano, Mieko Otani, Keiji Sano, Keiichi Kadoyama, Shogo Matsuyama, Taizo Taniguchi
    • Organizer
      The 22nd Biennial Meeting of the ISN/APSN Joint Meeting
    • Place of Presentation
      BEXCO, Busan, KOREA
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Presentation] マウス脳内synaptotagmin1の発現に対するニコチンの影響2009

    • Author(s)
      西本高明、角山圭一、谷口泰造、松本明、松山正剛
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Presentation] タウオパチーにおけるパーキンソン症状:SJLBマウスを用いた検討2009

    • Author(s)
      谷口泰造、千葉俊明、角山圭一、永田大典、田中昭二、川上知一、鈴木登、佐加良英治、松山正剛
    • Organizer
      第56回日本実験動物学会総会
    • Place of Presentation
      大宮ソニックシティ(埼玉県)
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Presentation] SJLBマウスとAPP変異マトランスジェニックマウスにおけるリン酸化プロテオーム解析2009

    • Author(s)
      鷹野正興, 尾谷三枝子, 富山貴美, 森啓, 谷口泰造, 角山圭一, 松山正剛
    • Organizer
      第82回日本薬理学会・年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-03-16
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Presentation] Phosphoproteome profiling of human tau with N279K mutation transgenic mice.2009

    • Author(s)
      Takano M, Otani M, Sano K, Kadoyama K, Matsuyama S, Taniguchi T
    • Organizer
      The 22nd Biennial Meeting of the ISN/APSN Joint Meeting
    • Place of Presentation
      Busan, Korea
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Presentation] タウオパチーにおけるパーキンソン症状:SJLBマウスを用いた検討2009

    • Author(s)
      谷口泰造、千葉俊明、角山圭一、永田大典、田中昭二、川上知一、鈴木登、佐加良英治、松山正剛
    • Organizer
      第56回日本実験動物学会総会
    • Place of Presentation
      大宮
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Presentation] Tauopathy induced Parkinsonism : analysis of SJLB mice.2009

    • Author(s)
      谷口泰造、角山圭一、炬口真理子、西本高明、千葉俊明、鈴木登、松本明、松山正剛
    • Organizer
      第52回日本神経化学会
    • Place of Presentation
      伊香保温泉 ホテル天坊(群馬県)
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Presentation] Tauopathy induced Parkinsonism : analysis of SJLB mice.2009

    • Author(s)
      谷口泰造、角山圭一、炬口真理子、西本高明、千葉俊明、鈴木登、松本明、松山正剛
    • Organizer
      第52回日本神経化学会
    • Place of Presentation
      群馬
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Presentation] Phosphoproteome profiling of the Donepezil treated SJLB mice2008

    • Author(s)
      Takano, M, Otani, M, Taniguchi, T
    • Organizer
      The 81st Annual Meeting of The Japanese Pharmacological Science
    • Place of Presentation
      in Yokohama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18500242
  • [Presentation] マウス海馬におけるテタヌス刺激で誘発される長期増強現象により変動する遺伝子群の解析2008

    • Author(s)
      角山圭一, 西本高明, 谷口泰造, 松本明, 松山正剛
    • Organizer
      第114回日本薬理学会近畿部会
    • Place of Presentation
      神戸商工会議所
    • Year and Date
      2008-11-14
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Presentation] LTP-like facilitation via GABA receptors blockade in the mouse dentate gyrus in vivo2008

    • Author(s)
      Matsuyama, S, Kadoyama, K, Matumoto, A, Taniguchi, T
    • Organizer
      The 81st Annual Meeting of The Japanese Pharmacological Science
    • Place of Presentation
      in Yokohama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18500242
  • [Presentation] マウス海馬におけるテタヌス刺激で誘発される長期増強現象により変動する遺伝子群の解析2008

    • Author(s)
      角山圭一、西本高明、谷口泰造、松本明、松山正剛
    • Organizer
      第114回日本薬理学会近畿部会
    • Place of Presentation
      神戸
    • Year and Date
      2008-11-14
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Presentation] Proteome profiling of the hippocampus in mutant tau(N279K)transgenic mice2007

    • Author(s)
      Takano, M, Otani, M, Sumida, M, Taniguchi, T
    • Organizer
      The 80th, Annual Meeting of The Japanese Pharmacological Science
    • Place of Presentation
      in Nagoya
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18500242
  • [Presentation] Causative candidates for the dementing diseases analysed by SJLB mice2007

    • Author(s)
      Taniguchi, T, Takano, M, Otani, M, Matsuyama, S
    • Organizer
      Neuro2007
    • Place of Presentation
      in Yokohama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18500242
  • [Presentation] N279K変異タウトランスジェニックマウス(SJLB)を用いた認知症関連蛋白の探索2007

    • Author(s)
      谷口 泰造
    • Organizer
      第50回神経化学会(Neuro2007)
    • Place of Presentation
      横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18500242
  • [Presentation] N279K変異タウトランスジェニックマウス(SJLB)を用いた認知症関連蛋白の探索2007

    • Author(s)
      谷口 泰造
    • Organizer
      第50回神経科学会(Neuro2007)
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18500242
  • 1.  Takenokuchi Mariko (10379430)
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    # of Collaborated Products: 2 results
  • 2.  MIYAMOTO Kazuhide (10415317)
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    # of Collaborated Products: 1 results
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    # of Collaborated Projects: 0 results
    # of Collaborated Products: 25 results
  • 24.  長崎 健
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  斎藤 尚亮
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results

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