Aishima Shinichi 相島慎一

… Alternative Names

AISHIMA Shinichi 相島慎一

相島慎一アイシマシンイチ

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Researcher Number	70346774
Affiliation (Current)	2025: 九州大学, 医学研究院, 教授
Affiliation (based on the past Project Information) *help	2025: 九州大学, 医学研究院, 教授 2022 – 2023: 九州大学, 医学研究院, 教授 2015 – 2023: 佐賀大学, 医学部, 教授 2013: 佐賀大学, 医学部, 教授 2011 – 2013: 九州大学, 医学(系)研究科(研究院), 准教授 … More 2010: Kyushu University, 医学研究院, 准教授 2010: 九州大学, 大学院・医学研究院, 准教授 2009: Kyushu University, 大学院・医学研究院, 助教 2005: 九大, 医学(系)研究科(研究院), 助手 2003 – 2004: 九州大学, 大学院・医学研究院, 助手 Less
Review Section/Research Field	Principal Investigator Human pathology / Basic Section 49020:Human pathology-related Except Principal Investigator Digestive surgery / Basic Section 55020:Digestive surgery-related / Basic Section 55010:General surgery and pediatric surgery-related
Keywords	Principal Investigator 肝内胆管癌 / 免疫微小環境 / 胆管癌 / 好中球 / 肝細胞癌 / 発がん / 酸化ストレス / 予後因子 / CCDC25 / サブタイプ … More / サイトカイン / リンパ球 / 抗ウイルス剤 / Sustained Viral Response / Direct acting Antivirals / CD8 / 肝炎ウイルス / 肝癌 / Hepcidin / 酸化ストレスう / 肝細胞がん / 活性酸素 / トランスフェリン受容体 / 鉄代謝 / 転移 / 発癌 / COX2 / iNOS / 胆管がん / 肝臓 / 浸潤能 / transporter / GLUT / SLIT / ROBO1 / ＳＡＬＬ４ / AFP / SiRNA / BilIN / トランスポーター / 増殖 / 浸潤 / 糖代謝 / ウイルス性肝炎 / 胆管癌前駆病変 / RAGE / Ezrin / S100P / 胆管前駆病変 / 肝炎 / 肝硬変 / 消化器 / リンパ節転移 / 14-3-3蛋白 / 腫瘍進展形態 / ラミニンγ2鎖 / Gastric foveolar type / 胃型粘液 / オステオポンチン / ラミニン5 … More Except Principal Investigator ミニチュアヒト肝臓 / ex vivo培養 / オルガノイド / ヒト由来機能性肝細胞・胆管細胞 / 脱細胞鋳型 / ex vivo還流培養 / 脱細胞鋳型肝臓 / 肝細胞癌 / 類洞構造 / ex vivo 培養 / 医工連携 / 機能性ゲル基材 / 細胞鋳型肝臓 / 医工連携研究 / 再生医工学 / ヒトiPS細胞 / ex vivoモデル / 浸潤・転移 / 不死化ヒト肝細胞 / ヒト初代培養肝細胞 / 創薬 / プロテオーム / Sphere / 化合物ライブラリー / 造血幹細胞 / がん幹細胞 / 集学的治療 / Type IVcollagen / plasma fibronectin / 腹膜播種 / sphere / シグナル伝達 / トランスレーショナルリサーチ / 薬剤反応性 / 細胞・組織 / 外科 / 癌 / Il-17 / STAT3 / 腫瘍関連マクロファージ / HLA　I / HLA I / PD-L1 / 肝臓外科学 Less

Elucidation of the role of neutrophil extracellular traps in biliary tract cancerPrincipal Investigator
- Principal Investigator
  
  相島慎一
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Kyushu University
ex vivo還流培養による精緻な組織構築を実現したミニチュアヒト肝臓の創成
- Principal Investigator
  
  山下洋市
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  ASO CORPORATION(ASO IIZUKA HOSPITAL)
肝内胆管癌のサブタイプ別にみる分子異常と免疫微小環境の包括的研究Principal Investigator
- Principal Investigator
  
  相島慎一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Kyushu University
  Saga University
Innovative medicine brought about by the creation of miniature human liver using ex vivo culture through medical-engineering collaboration
- Principal Investigator
  
  Yamashita Yoichi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  ASO CORPORATION(ASO IIZUKA HOSPITAL)
  Kumamoto University
Pathological investigation of microenvironment in the liver cancer treated by direct anti-viral drugsPrincipal Investigator
- Principal Investigator
  
  Aishima Shinichi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Saga University
Development of innovative treatment for liver cancer by elucidation of mechanism of invasion and metastasis liver cancer using miniature human liver
- Principal Investigator
  
  YAMASHITA Youichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Pathological investigation of iron regulatory protein in the progression of hepatobiliary malignancyPrincipal Investigator
- Principal Investigator
  
  Aishima Shinichi
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Saga University
Development of Innovative Treatment Targeting the Sphere Formation Mechanism Involving Cancer Stem Cells
- Principal Investigator
  
  Maehara Yoshihiko
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Digestive surgery
- Research Institution
  Fukuoka Dental College
  Kyushu University
Microenvironment in hepatocellular carcinoma
- Principal Investigator
  
  SHIRABE Ken
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Different mechanism of carcinogenesis and development in intrahepatic cholangiocarcinoma according to the level of bile ductsPrincipal Investigator
- Principal Investigator
  
  AISHIMA Shinichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
The investigation of carcinogenesis for intrahepatic cholangiocarcinoma arising from chronic hepatitis or liver cirrhosisPrincipal Investigator
- Principal Investigator
  
  AISHIMA Shinichi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
肝内胆管癌の浸潤・転移における細胞接着分子の発現とその制御機構の解明Principal Investigator
- Principal Investigator
  
  相島慎一
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University
肝内胆管癌における多段階発癌・発育進展機序の解明Principal Investigator
- Principal Investigator
  
  相島慎一
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Kyushu University

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All Journal Article Presentation Book

[Book] 病理と臨床2013
- Author(s)
  相島慎一、小田義直
- Total Pages
  7
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-23590399
[Book] 病理と臨床　特集胆膵病理I2013
- Author(s)
  相島慎一、小田義直
- Total Pages
  7
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-23590399
[Book] 肝胆膵2011　特集混合型肝癌および胆管形質を示す肝細胞癌：肝ステム細胞のインパクト2011
- Author(s)
  相島慎一
- Publisher
  株式会社アークメディア
- Data Source
  KAKENHI-PROJECT-23590399
[Book] 肝癌(胆管嚢胞腺癌/胆管嚢胞腺腫腫瘍病理鑑別診断アトラス)2010
- Author(s)
  相島慎一
- Data Source
  KAKENHI-PROJECT-21790355
[Book] 病理形態学キーワード2010病理と臨床【臨時増刊号】28(第8章肝曩胞性病変)2010
- Author(s)
  相島慎一
- Data Source
  KAKENHI-PROJECT-21790355
[Journal Article] Transferrin receptor 1 overexpression is associated with tumor dedifferentiation and acts as a potential prognostic indicator of hepatocellular carcinoma.2019
- Author(s)
  Adachi Makiko, Kai Keita, Yamaji Koutaro, Ide Takao, Noshiro Hirokazu, Kawaguchi Atsushi, Aishima Shinichi
- Journal Title
  
  Histopathology
  
  Volume: 印刷中 Issue: 1 Pages: 63-73
- DOI
  10.1111/his.13847
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08347
[Journal Article] IFN-γ Promotes Epithelial-Mesenchymal Transition and the Expression of PD-L1 in Pancreatic Cancer2019
- Author(s)
  Imai Daisuke、Yoshizumi Tomoharu、Okano Shinji、Itoh Shinji、Ikegami Toru、Harada Noboru、Aishima Shinichi、Oda Yoshinao、Maehara Yoshihiko
- Journal Title
  
  Journal of Surgical Research
  
  Volume: 240 Pages: 115-123
- DOI
  10.1016/j.jss.2019.02.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K21359, KAKENHI-PROJECT-15H05792
[Journal Article] Evaluation of techniques to prevent colorectal anastomotic leakage.2015
- Author(s)
  Ikeda T, Kumashiro R, Oki E, Taketani K, Ando K, Aishima S, Akahoshi T, Morita M, Maehara Y.
- Journal Title
  
  J Surg Res.
  
  Volume: 194(2): Issue: 2 Pages: 450-7
- DOI
  10.1016/j.jss.2014.11.045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05792
[Journal Article] Education and imaging. Hepatology: Rare Stevens-Johnson syndrome and vanishing bile duct syndrome induced by acetaminophen, requiring liver transplantation.2015
- Author(s)
  Harimoto N, Wang H, Ikegami T, Takeishi K, Itoh S, Yamashita YI, Yoshizumi T, Aishima S, Shirabe K, Oda Y, Maehara Y.
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: 30(4): Issue: 4 Pages: 656-656
- DOI
  10.1111/jgh.12849
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05792
[Journal Article] Follicular pancreatitis, report of a case clinically mimicking pancreatic cancer and literature review.2014
- Author(s)
  Mizuuchi Y. Aishima S, Hattori M, Ushijima Y, Aso A, Takahata S, Ohtsuka T, Ueda J, Tanaka M, Oda Y.
- Journal Title
  
  Pathol Res Pract.
  
  Volume: 210(2) Issue: 2 Pages: 118-122
- DOI
  10.1016/j.prp.2013.09.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J03401, KAKENHI-PROJECT-23590399
[Journal Article] Histological features of precancerous and early cancerous lesions of biliary tract carcinoma.2014
- Author(s)
  Aishima S, Kubo Y, Tanaka Y, Oda Y
- Journal Title
  
  J Hepatobiliary Pancreat Sci
  
  Volume: January 21 Issue: 7 Pages: 0-0
- DOI
  10.1002/jhbp.71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590399
[Journal Article] Prognostic impact of programmed cell death 1 ligand 1 expression in human leukocyte antigen class I-positive hepatocellular carcinoma after curative hepatectomy.2014
- Author(s)
  Umemoto Y, Okano S, Matsumoto Y, Nakagawara H, Matono R, Yoshiya S, Yamashita YI, Yoshizumi T, Ikegami T, Soejima Y, Harada M, Aishima S, Oda Y, Shirabe K, Maehara Y.
- Journal Title
  
  J Gastroenterol.
  
  Volume: not determined Issue: 1 Pages: 65-75
- DOI
  10.1007/s00535-014-0933-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390320, KAKENHI-PROJECT-24501331, KAKENHI-PROJECT-26670583, KAKENHI-PROJECT-15K10167
[Journal Article] Different roles of inducible nitric oxide synthase and cyclooxygenase-2 in carcinogenesis and metastasis of intrahepatic cholangiocarcinoma2013
- Author(s)
  Aishima S, Mano Y, Tanaka Y, Kubo Y, Shirabe K, Maehara Y, Oda Y
- Journal Title
  
  Hum Pathol
  
  Volume: 44 Pages: 1031-7
- Data Source
  KAKENHI-PROJECT-23590399
[Journal Article] Podoplanin expression in cancer-associated fibroblasts enhances tumor progression of invasive ductal carcinoma of the pancreas.2013
- Author(s)
  Shindo K, Aishima S, Ohuchida K, Fujiwara K, Fujino M, Mizuuchi Y, Hatton M, Mizumoto K. Tanaka M, Oda Y.
- Journal Title
  
  Mol Cancer
  
  Volume: 12(1) Issue: 1 Pages: 168-168
- DOI
  10.1186/1476-4598-12-168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J03401, KAKENHI-PROJECT-13J03692, KAKENHI-PROJECT-23590399, KAKENHI-PROJECT-23592013, KAKENHI-PROJECT-24390319, KAKENHI-PROJECT-24592031
[Journal Article] Decreased roundabout 1 expression promotes development of intrahepatic cholangiocarcinoma.2013
- Author(s)
  Mano Y, Aishima S, Fukuhara T, Tanaka Y, Kubo Y, Motomura T, Toshima T, Iguchi T, Shirabe K, Maehara Y, Oda Y
- Journal Title
  
  Hum Pathol
  
  Volume: Nov;44(11) Issue: 11 Pages: 2419-26
- DOI
  10.1016/j.humpath.2013.03.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590399
[Journal Article] Tumor-Associated Macrophage Promotes Tumor Progression via STAT3 Signaling in Hepatocellular Carcinoma.2013
- Author(s)
  119. Mano Y, Aishima S, Fujita N, Tanaka Y, Kubo Y, Motomura T, Taketomi A, Shirabe K, Maehara Y, Oda Y.
- Journal Title
  
  Pathobiology.
  
  Volume: 80 Issue: 3 Pages: 146-154
- DOI
  10.1159/000346196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590399, KAKENHI-PROJECT-24390320
[Journal Article] Decreased roundabout 1 expression promotes development of intrahepatic cholangiocarcinoma2013
- Author(s)
  Mano Y, Aishima S, Fukuhara T, Tanaka Y, Kubo Y, Motomura T, Toshima T, Iguchi T, Shirabe K, Maehara Y, Oda Y.
- Journal Title
  
  Hum Pathol
  
  Volume: 44 Pages: 2419-26
- Data Source
  KAKENHI-PROJECT-23590399
[Journal Article] An increase in the number of predictive factors augments the likelihood of malignancy in branch duct intraductal papillary mucinous neoplasm of the pancreas2012
- Author(s)
  Ohtsuka T, Kono H, Nagayoshi Y, Mori Y, Tsutsumi K, Sadakari Y, Takahata S, Morimatsu K, Aishima S, Igarashi H, Ito T, Ishigami K, Nakamura M, Mizumoto K, Tanaka M
- Journal Title
  
  Surgery
  
  Volume: 151 Pages: 76-83
- NAID
  120005324432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590399
[Journal Article] CD271^+ subpopulation of pancreatic stellate cells correlates with prognosis of pancreatic cancer and is regulated by interaction with cancer cells2012
- Author(s)
  Kenji Fujiwara
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 12 Pages: e52682-e52682
- DOI
  10.1371/journal.pone.0052682
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J01237, KAKENHI-PROJECT-22591523, KAKENHI-PROJECT-22591524, KAKENHI-PROJECT-23590399, KAKENHI-PROJECT-23591897, KAKENHI-PROJECT-23592013, KAKENHI-PROJECT-23791542, KAKENHI-PROJECT-23791544, KAKENHI-PROJECT-24390319, KAKENHI-PROJECT-24591014, KAKENHI-PROJECT-24592031, KAKENHI-PROJECT-24791430, KAKENHI-PROJECT-24791431
[Journal Article] Significance of dysadherin and E-cadherin expression in differentiated-type gastric carcinoma with submucosal invasion2011
- Author(s)
  Maehata Y, Hirahashi M, Aishima S, Kishimoto J, Hirohashi S, Yao T, Takashima H, Tsuneyoshi M, Oda Y
- Journal Title
  
  Hum Pathol
  
  Volume: 42 Pages: 558-567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590399
[Journal Article] Nuclear atypia grading score is a useful prognostic factor in papillary gastric adenocarcinoma2011
- Author(s)
  Nakashima Y, Yao T, Hirahashi M, Aishima S, Kakeji Y, Maehara Y, Tsuneyoshi M.
- Journal Title
  
  Histopathology
  
  Volume: 59 Issue: 5 Pages: 841-849
- DOI
  10.1111/j.1365-2559.2011.04035.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590399
[Journal Article] Performance of radiological methods in diagnosing hepatocellular carcinoma preoperatively in a recipient of living related liver transplantation: comparison with step section histopathology.2011
- Author(s)
  Hirakawa M, Yoshimitsu K, Irie H, Tajima T, Nishie A, Asayama Y, Ishigami K, Kakihara D, Taketomi A, Aishima S, Honda H
- Journal Title
  
  Jpn J Radiol
  
  Volume: 29 Pages: 129-137
- NAID
  50007960200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590399
[Journal Article] Outcomes of hepatic resection for huge hepatocellular carcinoma (≧10 cm in diameter)2011
- Author(s)
  Yamashita Y., et al
- Journal Title
  
  J SurgOncol
  
  Volume: 104 Issue: 3 Pages: 292-8
- DOI
  10.1002/jso.21931
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249072, KAKENHI-PROJECT-22659246, KAKENHI-PROJECT-23590399
[Journal Article] Cystic tumors of the liver : On the problems of diagnostic criteria2011
- Author(s)
  Mano Y,, et al
- Journal Title
  
  Pathol Res Pract
  
  Volume: 207 Issue: 10 Pages: 659-63
- DOI
  10.1016/j.prp.2011.07.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249072, KAKENHI-PROJECT-22659246, KAKENHI-PROJECT-23590399
[Journal Article] Different roles of S100P Overexpression in Intrahepatic Cholangiocarcinoma : Carcinogenesis of Perihilar Type and Aggressive Behavior of Peripheral Type.2011
- Author(s)
  Aishima S, et al.
- Journal Title
  
  American Journal of Surgical Pathol
  
  Volume: 35 Pages: 590-598
- NAID
  120004951589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790355
[Journal Article] Different roles of S100P Overexpression in Intrahepatic Cholangiocarcinoma: Carcinogenesis of Perihilar Type and Aggressive Behavior of Peripheral Type.2011
- Author(s)
  Aishima S, Fujita N, Mano Y, Kubo Y, Tanaka Y, Taketomi A, Shirabe K, Maehara Y, Oda Y.
- Journal Title
  
  Am J Surg Pathol. 35
  
  Pages: 590-598
- NAID
  120004951589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790355
[Journal Article] Histologic classification of microscopic portal venous invasion to predict prognosis in hepatocellular carcinoma2011
- Author(s)
  Fujita N, Aishima S, Iguchi T, Mano Y, Taketomi A, Shirabe K, Honda H, Tsuneyoshi M, Oda Y
- Journal Title
  
  Human Pathol
  
  Volume: 42 Pages: 1531-1538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590399
[Journal Article] Invasive carcinoma derived from intestinal-type intraductal papillary mucinous neoplasm is associated with minimal invasion, colloid carcinoma, and less invasive behavior, leading to a better prognosis2011
- Author(s)
  Nakata K, Ohuchida K, Aishima S, Sadakari Y, Kayashima T, Miyasaka Y, Nagai E, Mizumoto K, Tanaka M, Tsuneyoshi M, Oda Y
- Journal Title
  
  Pancreas
  
  Volume: 40 Pages: 581-587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590399
[Journal Article] Histological and immunohistological findings in biliary intraepithelial neoplasia arising from a background of chronic biliary disease compared with liver cirrhosis of non-biliary aetiology2011
- Author(s)
  Aishima S., et al
- Journal Title
  
  Histopathology
  
  Volume: 59 Issue: 5 Pages: 867-75
- DOI
  10.1111/j.1365-2559.2011.04011.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249072, KAKENHI-PROJECT-23590399
[Journal Article] Different roles of S100P Overexpression in Intrahepatic Cholangiocarcinoma: Carcinogenesis of Perihilar Type and Aggressive Behavior of Peripheral Type.2011
- Author(s)
  Aishima S, Fujita N, Mano Y, Kubo Y, Tanaka Y, Taketomi A, Shirabe K, Maehara Y, Oda Y
- Journal Title
  
  Am J Surg Pathol
  
  Volume: 35 Pages: 590-598
- NAID
  120004951589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590399
[Journal Article] Prognostic significance of preoperative imaging in recipients of living donor liver transplantation for hepatocellular carcinoma.2011
- Author(s)
  Sugimachi K, Shirabe K, Taketomi A, Soejima Y, Iguchi T, Takeishi K, Toshima T, Aishima S, Tajima T, Maehara Y.
- Journal Title
  
  Transplantation
  
  Volume: 91 Pages: 570-574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590399
[Journal Article] MicroRNA-10b is overexpressed in pancreatic cancer, promotes its invasiveness, and correlates with a poor prognosis2011
- Author(s)
  Nakata K, Ohuchida K, Mizumoto K, Kayashima T, Ikenaga N, Sakai H, Lin C, Fujita H, Otsuka T, Aishima S, Nagai E, Oda Y
- Journal Title
  
  Surgery
  
  Volume: 150 Pages: 916-922
- Data Source
  KAKENHI-PROJECT-23590399
[Journal Article] Down-regulation of artery in moderately differentiated hepatocellular carcinoma related to tumor development.2010
- Author(s)
  Fujita N, Aishima S, Iguchi T, Nishihara Y, Yamamoto H, Taketomi A, Oda Y, Honda H, Tsuneyoshi M
- Journal Title
  
  Hum Pathol 41
  
  Pages: 838-847
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790355
[Journal Article] A history of acute pancreatitis in intraductal papillary mucinous neoplasms of the pancreas is a potential predictive factor for malignant papillary subtype.2010
- Author(s)
  Tsutsumi K, Ohtsuka T, Oda Y, Sadakari Y, Mori Y, Aishima S, Takahata S, Nakamura M, Mizumoto K, Tanaka M.
- Journal Title
  
  Pancreatology. 10
  
  Pages: 707-712
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790355
[Journal Article] p62+ Hyaline Inclusions in Intrahepatic Cholangiocarcinoma Associated With Viral Hepatitis or Alcoholic Liver Disease2010
- Author(s)
  Aishima S, et al.
- Journal Title
  
  American Journal of Clinical Pathology
  
  Volume: 134 Pages: 457-465
- NAID
  120005227181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790355
[Journal Article] p62+ hyaline inclusions in intrahepatic cholangiocarcinoma associated with viral hepatitis or alcoholic liver disease.2010
- Author(s)
  Aishima S, Fujita N, Mano, Iguchi T, Taketomi A, Maehara Y, Oda Y, Tsuneyoshi M.
- Journal Title
  
  Am J Clin Pathol. 134
  
  Pages: 457-465
- NAID
  120005227181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790355
[Journal Article] S100P is a novel marker to identify intraductal papillary mucinous neoplasms.2010
- Author(s)
  Nakata K, Nagai E, Ohuchida K, Hayashi A, Miyasaka Y, Aishima S, Oda Y, Mizumoto K, Tanaka M, Tsuneyoshi M
- Journal Title
  
  Hum Pathol 41
  
  Pages: 824-831
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790355
[Journal Article] Decreased expression of focal adhesion kinase is associated with a poor prognosis in extrahepatic bile duct carcinoma.2010
- Author(s)
  Hayashi A, Aishima S, et al.
- Journal Title
  
  Human Pathology
  
  Volume: 41 Pages: 859-866
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790355
[Journal Article] Clinicopathological Prognostic Factors After Hepatectomy for Patients with Mass-Forming Type Intrahepatic Cholangiocarcinoma: Relevance of the Lymphatic Invasion Index.2010
- Author(s)
  Shirabe K, Mano Y, Taketomi A, Soejima Y, Uchiyama H, Aishima S, Kayashima H, Ninomiya M, Maehara Y
- Journal Title
  
  Ann Surg Oncol 17
  
  Pages: 1816-1822
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790355
[Journal Article] Decreased expression of focal adhesion kinase is associated with a poor prognosis in extrahepatic bile duct carcinoma.2010
- Author(s)
  Hayashi A, Aishima S, Inoue T, Nakata K, Morimatsu K, Nagai E, Oda Y, Tanaka M, Tsuneyoshi M.
- Journal Title
  
  Hum Pathol. 451
  
  Pages: 859-866
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790355
[Journal Article] Prognostic importance of the gross classification of hepatocellular carcinoma in living donor-related liver transplantation.2010
- Author(s)
  Shirabe K, Aishima S, Taketomi A, Soejima Y, Uchiyama H, Kayashima H, Ninomiya M, Mano Y, Maehara Y.
- Journal Title
  
  Br J Surg. 98
  
  Pages: 261-267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790355
[Journal Article] Pdcd4 expression in intraductal papillary mucinous neoplasm of the pancreas: its association with tumor progression and proliferation.2010
- Author(s)
  Hayashi A, Aishima S, Miyasaka Y, Nakata K, Morimatsu K, Oda Y, Nagai E, Oda Y, Tanaka M, Tsuneyoshi M.
- Journal Title
  
  Hum Pathol. 41
  
  Pages: 1507-1515
- NAID
  120005227180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790355
[Journal Article] Invasive carcinoma derived from the nonintestinal type intraductal papillary mucinous neoplasm of the pancreas has a poorer prognosis than that derived from the intestinal type.2010
- Author(s)
  Sadakari Y, Ohuchida K, Nakata K, Ohtsuka T, Aishima S, Takahata S, Nakamura M, Mizumoto K, Tanaka M
- Journal Title
  
  Surgery 147
  
  Pages: 812-817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790355
[Journal Article] CD10+ fibroblasts are more involved in the progression of hilar/extrahepatic cholangiocarcinoma than of peripheral intrahepatic cholangiocarcinoma.2009
- Author(s)
  Nishihara Y, Aishima S, et al.
- Journal Title
  
  Histopathology 55
  
  Pages: 423-431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790355
[Journal Article] Decreased intratumoral arteries reflect portal tract destruction and aggressive characteristics in intrahepatic cholangiocarcinoma.2009
- Author(s)
  Aishima S, et al.
- Journal Title
  
  Histopathology 54
  
  Pages: 452-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790355
[Journal Article] Clinicopathological correlates of aspartyl (asparaginyl) beta-hydroxylase over-expression in cholangiocarcinoma.2004
- Author(s)
  Maeda T, Aishima S et al.
- Journal Title
  
  Cancer Detect Prev. 28
  
  Pages: 313-318
- Data Source
  KAKENHI-PROJECT-15790187
[Journal Article] Decreased expression of osteopontin is related to tumor aggressiveness and clinical outcome of intrahepatic cholangiocarcinoma.2004
- Author(s)
  Terashi T, Aishima S. et al.
- Journal Title
  
  Liver int. 24
  
  Pages: 38-45
- Data Source
  KAKENHI-PROJECT-15790187
[Journal Article] Aberrant Expression of Laminin Gamma 2 Chain and Its Prognostic Significance in Intrahepatic Cholangiocarcinoma According to Growth Morphology.2004
- Author(s)
  Aishima S et al.
- Journal Title
  
  Modern Pathology 17
  
  Pages: 938-945
- Data Source
  KAKENHI-PROJECT-15790187
[Journal Article] Role of expression of focal adhesion kinase in progression of hepatocellular carcinoma.2004
- Author(s)
  Ito S, Aishima S et al.
- Journal Title
  
  Clin Cancer Res. 15
  
  Pages: 2812-2817
- Data Source
  KAKENHI-PROJECT-15790187
[Journal Article] Different expression of glucose transporters in the progression of intrahepatic cholangiocarcinoma
- Author(s)
  Kubo Y, Aishima S, Tanaka Y, Shindo K, Mizuuchi Y, Abe K, Shirabe K, Maehara Y, Honda H, Oda Y
- Journal Title
  
  Hum Pathol
  
  Volume: 2014
- Data Source
  KAKENHI-PROJECT-23590399
[Presentation] Development of a functional miniature liver based on the right lobe of mice2023
- Author(s)
  Lucija Stefan1, Mario Kokichi Uehara1, Fanqi Wu1, Yukako Fukuda1, Yo-Ichi Yamashita2, Shinichi Aishima3, Yasuhiro Ikegami1, Yusuke Sakai1, Hiroyuki Ijima1 1 Kyushu University, Dept. of Chemical Engineering 2 AsoIizuka Hospital, 3Kyushu University, Dept. of ScientificPathology
- Organizer
  第23回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-20H03744
[Presentation] 脱細胞化組織の応用展開2022
- Author(s)
  井嶋博之, 呉帆琦, 福田有嘉子, 小柳和也, 趙宰庸, 堺裕輔, 宮田辰徳, 中尾陽佑, 山尾宣暢, 相島慎一, 山下洋市, 馬場秀夫
- Organizer
  第21回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20H03744
[Presentation] Development and Functional Evaluation of a Miniature Liver Model （ミニチュア肝臓モデルの開発と機能評価）2022
- Author(s)
  Uehara Uyeda Mario Kokichi, Wu Fanqi, Fukuda Yukako, Sakai Yusuke, Shirakigawa Nana, Miyata Tatsunori, Nakao Yosuke, Yamao Takanobu, Aishima Shinichi, Yamashita Yo-ichi, Baba Hideo, Ijima Hiroyuki
- Organizer
  化学工学会第87年会
- Data Source
  KAKENHI-PROJECT-20H03744
[Presentation] Transferrin receptor 1 overexpression is associated with tumor dedifferentiation and acts as a potential prognostic indicator of hepatocellular carcinoma.2018
- Author(s)
  Adachi Makiko, Kai Keita, Yamaji Koutaro, Ide Takao, Noshiro Hirokazu, Kawaguchi Atsushi, Aishima Shinichi
- Organizer
  日本消化器癌発生学会
- Data Source
  KAKENHI-PROJECT-15K08347
[Presentation] 末梢型肝内胆管癌の病理学的特徴: 傍肝門型との比較2012
- Author(s)
  相島慎一、間野洋平、久保雄一郎、田中ゆき、調憲、前原喜彦、小田義直
- Organizer
  第48回日本肝臓学会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23590399
[Presentation] 肝内胆管癌におけるGlucose transporter(GLUT)の役割2012
- Author(s)
  久保雄一郎, 相島慎一, 半田瑞樹, 田中ゆき, 間野洋平, 小田義直
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590399
[Presentation] 肝内胆管癌の発癌・転移におけるiNOS, COX2発現の役割2012
- Author(s)
  相島慎一, 久保雄一郎, 田中ゆき, 間野洋平, 小田義直
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590399
[Presentation] 肝内胆管癌の発癌・転移におけるiNOS、COX2発現の役割2012
- Author(s)
  相島慎一、久保雄一郎、田中ゆき、間野洋平、小田義直:
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590399
[Presentation] 肝内胆管癌におけるGlucose transporter (GULT)の役割2012
- Author(s)
  久保雄一郎、相島慎一、半田瑞樹、田中ゆき、間野洋平、小田義直
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590399
[Presentation] 混合型肝癌の組織診断―問題点と診断手順―2011
- Author(s)
  相島慎一、間野洋平、田中ゆき、久保雄一郎、武冨紹信、調憲、前原喜彦、小田義直
- Organizer
  第47回日本肝癌研究会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-23590399
[Presentation] 硬化性胆管炎、慢性胆管炎からの発癌：BilINを中心に2011
- Author(s)
  相島慎一、小田義直
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590399
[Presentation] 腫瘍関連マクロファージによる肝細胞癌におけるSTAT3シグナル活性化に関する研究2011
- Author(s)
  間野洋平, 相島慎一, 田中ゆき, 久保雄一郎, 藤田展宏, 武冨紹信, 前原喜彦, 小田義直
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590399
[Presentation] 肝硬変に生じるBilINの病理学的特徴.JDDW20102010
- Author(s)
  相島慎一、間野洋平、調憲
- Organizer
  第14回日本肝臓学会大会
- Place of Presentation
  横浜
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-21790355
[Presentation] 原発性肝癌の予後因子2010
- Author(s)
  相島慎一、藤田展宏、間野洋平、調憲、武冨紹信、前原喜彦、小田義直
- Organizer
  第14回日本肝臓学会大会
- Place of Presentation
  横浜
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-21790355
[Presentation] Intraductal papillary mucinous neoplasm(IPMN)におけるLiver intestinal cadherin発現の検討2010
- Author(s)
  森松克哉、相島慎一、林晃史、小田康徳、小田義直
- Organizer
  第99回日本病理学会総会
- Year and Date
  2010-04-28
- Data Source
  KAKENHI-PROJECT-21790355
[Presentation] 肝内胆管癌の発育・進展メカニズムの病理学的解明.Pathological investigation of tumor growth and progression of intrahepatic cholangiocarcinoma.2010
- Author(s)
  相島慎一
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21790355
[Presentation] Pathological investigation of tumor growth and progression of intrahepatic cholangiocarcinoma2010
- Author(s)
  Aishima S, et al.
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪市
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21790355
[Presentation] 肝内胆管癌におけるS100P、Ezrin発現の意義2010
- Author(s)
  相島慎一、藤田展宏、間野洋平、小田康徳、森松克哉、小田義直
- Organizer
  第99回日本病理学会
- Place of Presentation
  東京
- Year and Date
  2010-04-27
- Data Source
  KAKENHI-PROJECT-21790355
[Presentation] Decreased intratumoral arteries reflect portal tract destruction and aggressive characteristics in intrahepatic cholangiocarcinoma.2009
- Author(s)
  Aishima S, et al.
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜市(パシフィコ横浜)
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-21790355
[Presentation] 胆管癌におけるARG発現の生物学的意義
- Author(s)
  花木由香　相島慎一　服部正見　水内祐介　久保雄一郎　田中ゆき　小田義直
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590399
[Presentation] 慢性肝炎・肝硬変におけるBile duct adenomaの意義
- Author(s)
  相島慎一　久保雄一郎　田中ゆき　小田義直
- Organizer
  第103回日本病理学会総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-23590399
[Presentation] 膵・胆道細胞診の基礎
- Author(s)
  相島慎一
- Organizer
  第54回日本臨床細胞学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23590399
[Presentation] 膵神経内分泌腫瘍におけるGLUT1/2発現について
- Author(s)
  藤野稔　相島慎一　小田義直
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590399

1. YONEMITSU Yoshikazu (40315065)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. YAMASHITA Youichi (00404070)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
3. 井嶋博之 (10274515)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
4. SHIRABE Ken (70264025)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. SOEJIMA Yuji (30325526)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. MAEHARA Yoshihiko (80165662)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
7. YOSHIZUMI Tomoharu (80363373)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
8. IKEGAMI Toru (80432938)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
9. OKANO Shinji (10380429)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
10. 馬場秀夫 (20240905)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
11. TAKENOYAMA Mitsuhiro (10309966)

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12. 播本憲史 (00419582)

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13. 古山正 (00419590)

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14. 原田結 (00608507)

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15. 間野洋平 (10792244)

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16. 赤星朋比古 (20336019)

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17. 松本拓也 (20374168)

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19. 安藤幸滋 (20608864)

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20. 北尾洋之 (30368617)

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21. 森崎浩一 (30625801)

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22. 豊川剛二 (30627261)

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23. 吉野一郎 (40281547)

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24. 中島雄一郎 (40733564)

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36. 伊藤心二 (90382423)

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39. 中西良太 (90771254)

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40. 工藤健介 (90801663)

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41. 堤亮介 (60846541)

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53. 山本猛雄 (50911616)

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Aishima Shinichi 相島 慎一

AISHIMA Shinichi 相島 慎一

相島 慎一 アイシマ シンイチ

Research Projects

Research Products

Co-Researchers

Elucidation of the role of neutrophil extracellular traps in biliary tract cancerPrincipal Investigator

Principal Investigator

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ex vivo還流培養による精緻な組織構築を実現したミニチュアヒト肝臓の創成

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肝内胆管癌のサブタイプ別にみる分子異常と免疫微小環境の包括的研究Principal Investigator

Principal Investigator

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Innovative medicine brought about by the creation of miniature human liver using ex vivo culture through medical-engineering collaboration

Principal Investigator

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Research Institution

Pathological investigation of microenvironment in the liver cancer treated by direct anti-viral drugsPrincipal Investigator

Principal Investigator

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Review Section

Research Institution

Development of innovative treatment for liver cancer by elucidation of mechanism of invasion and metastasis liver cancer using miniature human liver

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Pathological investigation of iron regulatory protein in the progression of hepatobiliary malignancyPrincipal Investigator

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Development of Innovative Treatment Targeting the Sphere Formation Mechanism Involving Cancer Stem Cells

Principal Investigator

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Microenvironment in hepatocellular carcinoma

Principal Investigator

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Different mechanism of carcinogenesis and development in intrahepatic cholangiocarcinoma according to the level of bile ductsPrincipal Investigator

Principal Investigator

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The investigation of carcinogenesis for intrahepatic cholangiocarcinoma arising from chronic hepatitis or liver cirrhosisPrincipal Investigator

Principal Investigator

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Research Institution

肝内胆管癌の浸潤・転移における細胞接着分子の発現とその制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

肝内胆管癌における多段階発癌・発育進展機序の解明Principal Investigator

Principal Investigator

Aishima Shinichi 相島慎一

AISHIMA Shinichi 相島慎一

相島慎一アイシマシンイチ

[Book] 病理と臨床　特集胆膵病理I2013

[Book] 肝胆膵2011　特集混合型肝癌および胆管形質を示す肝細胞癌：肝ステム細胞のインパクト2011