OHKI Rieko 大木理恵子

Researcher Number	70356252
Other IDs	https://orcid.org/0000-0002-7775-6653
External Links
Affiliation (Current)	2024: 国立研究開発法人国立がん研究センター, 研究所, 独立ユニット長
Affiliation (based on the past Project Information) *help	2017 – 2023: 国立研究開発法人国立がん研究センター, 研究所, 独立ユニット長 2017: 国立研究開発法人国立がん研究センター, 研究所, ユニット長 2015 – 2016: 国立研究開発法人国立がん研究センター, 研究所, 主任研究員 2013 – 2014: 独立行政法人国立がん研究センター, 研究所, 主任研究員 2010 – 2012: 独立行政法人国立がん研究センター, 研究所, 研究員 2009: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, 細胞増殖因子研究部, 研究員
Review Section/Research Field	Principal Investigator Tumor biology / Basic Section 54040:Metabolism and endocrinology-related / Tumor biology / Medium-sized Section 58:Society medicine, nursing, and related fields / Basic Section 50010:Tumor biology-related / Tumor biology / General medical chemistry Except Principal Investigator Basic Section 50010:Tumor biology-related / Basic Section 48020:Physiology-related / Basic Section 49010:Pathological biochemistry-related / Dermatology
Keywords	Principal Investigator p53 / Akt / 神経内分泌腫瘍 / がん / PHLDA3 / がん抑制遺伝子 / 動物モデル / notch / Notch / 予防 … More / 食事療法 / 神経内分泌腫瘍抑制 / 遺伝子 / PHLDA3遺伝子 / がん遺伝子Akt / PHドメイン / 癌 / がん遺伝子 / P53 / 細胞内シグナル伝達 … More Except Principal Investigator がん抑制遺伝子 / HSF1 / 糖鎖 / 肝がん / FUCA1 / フコシル化 / N型糖鎖 / 腫瘍循環器学 / がん治療関連心機能障害 / PHLDA3 / E-cadherin / 細胞間接着 / PLEKHA5 / 口唇口蓋裂 / スキルス胃癌 / ストレス応答 / p53 / がん / 皮膚メラノーマ / 悪性黒色腫 / 皮膚腫瘍 / NLS / melanoma / IER5 Less

食事療法を用いた副作用のない非機能性の膵臓神経内分泌腫瘍の予防法・治療法の開発Principal Investigator
- Principal Investigator
  
  大木理恵子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  National Cancer Center Japan
がん抑制遺伝子PHLDA3の抗がん剤性心機能障害に対する生理作用の解明
- Principal Investigator
  
  野中美希
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Jikei University School of Medicine
肝臓におけるタンパク質フコシル化異常による疾患発症機構の解明
- Principal Investigator
  
  田端祐子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  National Cancer Center Japan
スキルス胃癌と口唇口蓋裂の発症に関わるPLEKHA5の分子機能の解析
- Principal Investigator
  
  山口英樹
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Sasaki Foundation
Mechanism of neuroendocrine tumor suppression by the tumor suppressor gene PHLDA3Principal Investigator
- Principal Investigator
  
  Ohki Rieko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  National Cancer Center Japan
Functional elucidation of the pro-oncogenic p53-IER5 pathway in cancers with wild-type p53
- Principal Investigator
  
  Aoki Kiyono
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  National Cancer Center Japan
様々な臓器に発生する神経内分泌腫瘍の全容解明～PHLDA3の機能解析を通じて～Principal Investigator
- Principal Investigator
  
  大木理恵子
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  National Cancer Center Japan
ＰＮＥＴ発癌に関するシグナル経路の解明ｐ５３，　ＡｋｔとＮｏｔｃｈ経路間の関連Principal Investigator
- Principal Investigator
  
  大木理恵子
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Tumor biology
- Research Institution
  National Cancer Center Japan
Functional analysis of PHLDA3, a repressor of Akt, to elucidate the mechanism of neuroendocrine tumor developmentPrincipal Investigator
- Principal Investigator
  
  Ohki Rieko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  National Cancer Center Japan
Role of IER5-HSF1 axis in malignant melanoma carcinogenesis
- Principal Investigator
  
  Yamano Shotaro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Japan Organization of Occupational Health and Safety Japan Bioassay Research Center
Functional analysis of PHLDA3, a tumor suppressor gene of neuroendocrine tumorsPrincipal Investigator
- Principal Investigator
  
  Ohki Rieko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  National Cancer Center Japan
Repression of the Akt pathway by a novel tumor suppressor gene PHLDA3 -towards development of tailor-made therapies-Principal Investigator
- Principal Investigator
  
  OHKI Rieko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  National Center of Neurology and Psychiatry
Novel p53 target genes involved in cross talk between oncogenic signals and p53 pathways.Principal Investigator
- Principal Investigator
  
  OHKI Rieko
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East

[Journal Article] Tissue factor-induced fibrinogenesis mediates cancer cell clustering and multiclonal peritoneal metastasis.2023
- Author(s)
  Makoto Miyazaki, Ayaka Nakabo, Yoshiko Nagano, Yuko Nagamura, Kazuyoshi Yanagihara, Rieko Ohki, Yoshikazu Nakamura, KiyokoFukami, JunKawamoto, Kenji Umayahara, Masaru Sakamoto, Keiichi Iwaya, and Hideki Yamaguchi.
- Journal Title
  
  Cancer Letters
  
  Volume: 553 Pages: 215983-215983
- DOI
  10.1016/j.canlet.2022.215983
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03523, KAKENHI-PROJECT-20F20414, KAKENHI-PROJECT-20K07605, KAKENHI-PROJECT-21K15518
[Journal Article] Integrin α5 mediates cancer cell-fibroblast adhesion and peritoneal dissemination of diffuse-type gastric carcinoma2022
- Author(s)
  Miyamoto Shingo、Nagano Yoshiko、Miyazaki Makoto、Nagamura Yuko、Sasaki Kazuki、Kawamura Takeshi、Yanagihara Kazuyoshi、Imai Toshio、Ohki Rieko、Yashiro Masakazu、Tanaka Masato、Sakai Ryuichi、Yamaguchi Hideki
- Journal Title
  
  Cancer Letters
  
  Volume: 526 Pages: 335-345
- DOI
  10.1016/j.canlet.2021.11.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07242, KAKENHI-PROJECT-21K07105, KAKENHI-PROJECT-20H03523, KAKENHI-PROJECT-20F20414, KAKENHI-PROJECT-20K07605
[Journal Article] PHLDA3 Is an Important Downstream Mediator of p53 in Squamous Cell Carcinogenesis2022
- Author(s)
  Saito Megumi、Sada Akane、Fukuyo Masaki、Aoki Kiyono、Okumura Kazuhiro、Tabata Yuko、Chen Yu、Kaneda Atsushi、Wakabayashi Yuichi、Ohki Rieko
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: 142 Issue: 21 Pages: 02271-5
- DOI
  10.1016/j.jid.2021.09.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16707, KAKENHI-PROJECT-19K07494, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20H03523, KAKENHI-PROJECT-20F20414, KAKENHI-PROJECT-18K07080, KAKENHI-PROJECT-20K07605
[Journal Article] Elaboration of Non-naturally Occurring Helical Tripeptides as p53–MDM2/MDMX Interaction Inhibitors2021
- Author(s)
  Su Aoze、Tabata Yuko、Aoki Kiyono、Sada Akane、Ohki Rieko、Nagatoishi Satoru、Tsumoto Kouhei、Wang Siyuan、Otani Yuko、Ohwada Tomohiko
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 69 Issue: 7 Pages: 681-692
- DOI
  10.1248/cpb.c21-00238
- NAID
  130008060029
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2021-07-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07605, KAKENHI-PROJECT-18H02552, KAKENHI-PROJECT-20H02531
[Journal Article] p53-PHLDA3-Akt Network: The Key Regulators of Neuroendocrine Tumorigenesis.2020
- Author(s)
  Yu Chen and Rieko Ohki*.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 21 Issue: 11 Pages: 4098-4098
- DOI
  10.3390/ijms21114098
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03523, KAKENHI-PROJECT-18F18758, KAKENHI-PROJECT-20F20414, KAKENHI-PROJECT-19K16732, KAKENHI-PROJECT-16H06276
[Journal Article] Identification and characterization of the binding sequences and target genes of p53 lacking the 1st transactivation domain.2020
- Author(s)
  Shiori Suzuki, Shuichi Tsutsumi, Yu Chen, Chikako Ozeki, Atsushi Okabe, Tatsuya Kawase, Hiroyuki Aburatani and Rieko Ohki.
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 2 Pages: 451-466
- DOI
  10.1111/cas.14279
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03587, KAKENHI-PROJECT-18F18758, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20H03523, KAKENHI-PROJECT-19K16732
[Journal Article] Nuclear import of IER5 is mediated by a classical bipartite nuclear localization signal and is required for HSF1 full activation2020
- Author(s)
  Shotaro Yamano, Makoto Kimura, Yu Chen, Naoko Imamoto, Rieko Ohki
- Journal Title
  
  Experimental Cell Research
  
  Volume: 386 Issue: 1 Pages: 111686-111686
- DOI
  10.1016/j.yexcr.2019.111686
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06235, KAKENHI-INTERNATIONAL-15K21744, KAKENHI-PLANNED-15H05929, KAKENHI-PROJECT-17H03587, KAKENHI-PROJECT-18H02442, KAKENHI-PROJECT-18F18758, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K16732
[Journal Article] IER5 Is a p53-Regulated Activator of HSF1 That Contributes to Promotion of Cancer.2019
- Author(s)
  Tatsuya Kawase, Yu Chen, Rieko Ohki.
- Journal Title
  
  Heat Shock Proteins
  
  Volume: 17 Pages: 253-272
- DOI
  10.1007/978-3-030-03952-3_13
- ISBN
  9783030039516, 9783030039523
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03587
[Journal Article] Recommendation of long-term and systemic management according to the risk factors in rectal NETs patients.2019
- Author(s)
  Kojima M, Chen Y, Ikeda K, Tsukada Y, Takahashi D, Kawano S, Amemiya K, Ito M, Ohki R, Ochiai A.
- Journal Title
  
  Sci Rep
  
  Volume: 9 Issue: 1 Pages: 2040-2040
- DOI
  10.1038/s41598-018-37707-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07035, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K16732, KAKENHI-PROJECT-17H03587, KAKENHI-PROJECT-18F18758
[Journal Article] Non-naturally Occurring Helical Molecules Can Interfere with p53–MDM2 and p53–MDMX Protein–Protein Interactions2019
- Author(s)
  AozeSu, Siyuan Wang, Akane Sada,Yuko Otani, Luhan Zhai, Xin Liu, Misa Sayama, Rieko Ohki and Tomohiko Ohwada.
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 67 Issue: 10 Pages: 1139-1143
- DOI
  10.1248/cpb.c19-00501
- NAID
  130007722045
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2019-10-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03587, KAKENHI-PROJECT-18F18758
[Journal Article] Overall Shape Constraint of Alternating /-Hybrid Peptides Containing Bicyclic Proline.2019
- Author(s)
  Siyuan Wang, Yuko Otani, Luhan Zhai, Aoze Su, Masayuki Nara, Masatoshi Kawahata, Kentaro Yamaguchi, Akane Sada, Rieko Ohki, Tomohiko Ohwada.
- Journal Title
  
  Organic Letters
  
  Volume: 21 Issue: 19 Pages: 7813-7817
- DOI
  10.1021/acs.orglett.9b02799
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03587, KAKENHI-PROJECT-18F18758
[Journal Article] 膵神経内分泌腫瘍のゲノム異常とプレシジョン・メディシンへの応用.2019
- Author(s)
  大木理恵子
- Journal Title
  
  肝胆膵
  
  Volume: 79 Pages: 1135-114
- Data Source
  KAKENHI-PROJECT-17H03587
[Journal Article] 膵神経内分泌腫瘍のゲノム異常とプレシジョン・メディシンへの応用.2019
- Author(s)
  大木理恵子
- Journal Title
  
  肝胆膵
  
  Volume: 79 Pages: 1135-1140
- Data Source
  KAKENHI-PROJECT-18F18758
[Journal Article] 膵神経内分泌腫瘍のがん遺伝子研究ーPHLDA3は膵神経内分泌腫瘍の運命を決定する.2018
- Author(s)
  冨永航平, チンヨ、大木理恵子.
- Journal Title
  
  臨床消化器内科（8月号: 特集膵神経内分泌腫瘍update）
  
  Volume: 33 Pages: 1099-1109
- Data Source
  KAKENHI-PROJECT-18F18758
[Journal Article] Functional loss of p53 cooperates with the in vivo microenvironment to promote malignant progression of gastric cancers.2018
- Author(s)
  Ohtsuka J, Oshima H, Ezawa I, Abe R, Oshima M, Ohki R.
- Journal Title
  
  Scientific Report
  
  Volume: 8 Issue: 1 Pages: 2291-2291
- DOI
  10.1038/s41598-018-20572-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06843, KAKENHI-PROJECT-18F18758
[Journal Article] PHLDA1, another PHLDA family protein that inhibits Akt.2018
- Author(s)
  Chen, Y., Takikawa, M., Tsutsumi, S., Yamaguchi, Y., Okabe, A., Shimada, M., Kawase, T., Sada, A., Ezawa, I., Takano, Y., Nagata, K. Suzuki, Y., Semba, K., Aburatani, H., and Ohki, R.
- Journal Title
  
  Cancer Sci
  
  Volume: 109 Issue: 11 Pages: 3532-3542
- DOI
  10.1111/cas.13796
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07183, KAKENHI-PROJECT-17H07378, KAKENHI-PROJECT-18F18758, KAKENHI-PROJECT-16H06276
[Journal Article] A vicious partnership between AKT and PHLDA3 to facilitate neuroendocrine tumors2017
- Author(s)
  Masahiro Takikawa and Rieko Ohki
- Journal Title
  
  Cancer Science
  
  Volume: 印刷中 Issue: 6 Pages: 1101-1108
- DOI
  10.1111/cas.13235
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26430133, KAKENHI-PROJECT-17H07378
[Journal Article] IER5 generates a novel hypo-phosphorylated active form of HSF1 and contributes to tumorigenesis.2016
- Author(s)
  Yoshinori Asano, Tatsuya Kawase, Atsushi Okabe, Shuichi Tsutsumi, Hitoshi Ichikawa, Satoko Tatebe, Issay Kitabayashi, Fumio Tashiro, Hideo Namiki, Tadashi Kondo, Kentaro Semba, Hiroyuki Aburatani, Yoichi Taya, Hitoshi Nakagama and Rieko Ohki
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 19174-19174
- DOI
  10.1038/srep19174
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430133, KAKENHI-PROJECT-24221011
[Journal Article] A novel p53 target gene FUCA1 encodes a fucosidase and regulates growth and survival of cancer cells.2016
- Author(s)
  Ezawa I, Sawai Y, Kawase T, Okabe A, Tsutsumi S, Ichikawa H, Kobayashi Y, Tashiro F, Namiki H, Kondo T, Semba K, Aburatani H, Taya Y, Nakagama H, Ohki R.
- Journal Title
  
  Cancer Sci.
  
  Volume: 印刷中 Issue: 6 Pages: 734-745
- DOI
  10.1111/cas.12933
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-26293342, KAKENHI-PROJECT-26430133, KAKENHI-PROJECT-16K10880
[Journal Article] PHLDA2 is a key oncogene-induced negative feedback inhibitor of EGFR/ErbB2 signaling via interference with AKT signaling.2015
- Author(s)
  Xiaoqi Wang, Guangyuan Li, Sanjay Koul, Rieko Ohki, Matthew Maurer, Alain Borczuk, Balazs Halmos.
- Journal Title
  
  Oncotarget
  
  Volume: 10 Issue: 38 Pages: 18632-18632
- DOI
  10.18632/oncotarget.3674
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430133
[Journal Article] PHLDA2 is a key oncogene-induced negative feedback inhibitor of EGFR/ErbB2 signaling via interference with AKT signaling2015
- Author(s)
  Xiaoqi Wang, Guangyuan Li, Sanjay Koul, Rieko Ohki, Matthew Maurer, Alain Borczuk, Balazs Halmos.
- Journal Title
  
  Oncotarget
  
  Volume: なし
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26430133
[Journal Article] Identification of Non-Coding RNAs Associated with Telomeres Using a Combination of enChIP and RNA Sequencing2015
- Author(s)
  Toshitsugu Fujita, Miyuki Yuno, Daisuke Okuzaki, Rieko Ohki, Hodaka Fujii
- Journal Title
  
  PLOS ONE
  
  Volume: 10 Issue: 4 Pages: e0123387-e0123387
- DOI
  10.1371/journal.pone.0123387
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25830131, KAKENHI-PROJECT-26430133, KAKENHI-PUBLICLY-15H01354, KAKENHI-PROJECT-15H04329
[Journal Article] 膵神経内分泌腫瘍の新規がん抑制遺伝子PHLDA3の発見2015
- Author(s)
  陳ヨ, 斉藤梢, 山口陽子, 大木理恵子
- Journal Title
  
  胆と膵
  
  Volume: 36 Pages: 515-523
- Data Source
  KAKENHI-PROJECT-26430133
[Journal Article] 新規がん抑制遺伝子PHLDA3によるAkt経路の制御機構と治療への展開－膵神経内分泌腫瘍の個別化医療開発を目指して－2014
- Author(s)
  山口　陽子・斉藤　梢・陳　ヨ・大木　理恵子
- Journal Title
  
  実験医学
  
  Volume: ７月増刊
- Data Source
  KAKENHI-PROJECT-23501279
[Journal Article] PHLDA3 is a novel tumor suppressor of pancreatic neuroendocrine tumors.2014
- Author(s)
  Ohki R, Saito K, Chen Y, Kawase T, Hiraoka N, Saigawa R, Minegishi M, Aita Y, Yanai G, Shimizu H, Yachida S, Sakata N, Doi R, Kosuge T, Shimada K, Tycko B,Tsukada T, Kanai Y, Sumi S, Namiki H, Taya Y, Shibata T, Nakagama H.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: Jun 10;111(23) Issue: 23
- DOI
  10.1073/pnas.1319962111
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-26430133, KAKENHI-PROJECT-26462053
[Journal Article] PHLDA3 is a novel tumor suppressor of pancreatic neuroendocrine tumors2014
- Author(s)
  Rieko Ohki, et. al, Tatsuhiro Shibata and Hitoshi Nakagama.
- Journal Title
  
  PNAS
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501279
[Journal Article] PHLDA3 is a novel tumor suppressor of neuroendocrine tumors2014
- Author(s)
  Rieko Ohki, Kozue Saito, Yu Chen, Tatsuya Kawase, Yukie Aita, Nobuyoshi Hiraoka, Raira Saigawa, Maiko Minegishi, Goichi Yanai, Hiroko Shimizu, Shinichi Yachida, Naoaki Sakata, Akihiko Yokoyama, Ryuichiro Doi, Tomoo Kosuge, Kazuaki Shimada, Benjamin Tycko, Toshihiko Tsukada, Yae Kanai, Shoichiro Sumi, Hideo Namiki, Yoichi Taya, Tatsuhiro Shibata and Hitoshi Nakagama
- Journal Title
  
  PNAS
  
  Volume: 111(23)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501279
[Journal Article] Identification of telomere-associated molecules by engineered DNA-binding molecule-mediated chromatin immunoprecipitation (enChIP).2013
- Author(s)
  Toshitsugu Fujita, Yoshinori Asano, Junko Ohtsuka, Yoko Takada, Kazunobu Saito, Rieko Ohki, Hodaka Fujii.
- Journal Title
  
  Scientific Reports
  
  Volume: 3 Issue: 1 Pages: 3-3
- DOI
  10.1038/srep03171
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501279, KAKENHI-PUBLICLY-25118512, KAKENHI-PROJECT-25830131
[Journal Article] Cancer susceptibility polymorphism of p53 at codon 72 affects phosphorylation and degradation of p53 protein2011
- Author(s)
  Chikako Ozeki, T. Shibata, T. Kohno, Y. Sawai, K. Okamoto, J. Yokota, F. Tashiro, S. Tanuma, R. Sakai, T. Kawase, I. Kitabayashi, Y. Taya and Rieko Ohki
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 286 Pages: 18251-18260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501279
[Journal Article] Cancer susceptibility polymorphism of p53 at codon 72 affects phosphorylation and degradation of p53 protein.2011
- Author(s)
  Rieko Ohki
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 286 Pages: 18251-18260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790299
[Journal Article] Cancer susceptibility polymorphism of p53 at codon 72 affects phosphorylation and degradation of p53 protein2011
- Author(s)
  Chikako Ozeki, Tatsuhiro Shibata, Takashi Kohno, Yuichiro Sawai, Koji Okamoto, Jun Yokota, Fumio Tashiro, Seiichi Tanuma, Ryuichi Sakai, Tatsuya Kawase, Issay Kitabayashi, Yoichi Taya and Rieko Ohki#
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: Vol.286 Pages: 18251-18260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501279
[Journal Article] PHLDA3は新規Akt抑制因子であり、癌化を抑制する因子である2010
- Author(s)
  大木理恵子、川瀬竜也
- Journal Title
  
  生体の科学 61巻6号
  
  Pages: 560-567
- NAID
  40017140420
- Data Source
  KAKENHI-PROJECT-21790299
[Journal Article] PHLDA3は新規Akt抑制因子であり、癌化を抑制する因子である2010
- Author(s)
  大木理恵子
- Journal Title
  
  生体の科学
  
  Volume: 61 Pages: 560-567
- NAID
  40017140420
- Data Source
  KAKENHI-PROJECT-21790299
[Journal Article] PHLDA3は新規Akt抑制因子であり、癌化を抑制する因子である2010
- Author(s)
  大木理恵子
- Journal Title
  
  細胞工学
  
  Volume: 29 Pages: 599-605
- NAID
  40017140420
- Data Source
  KAKENHI-PROJECT-21790299
[Journal Article] PHLDA3は新規Akt抑制因子であり、癌化を抑制する因子である。2010
- Author(s)
  川瀬竜也、大木理恵子
- Journal Title
  
  細胞工学Special Review vol.29
  
  Pages: 599-605
- NAID
  40017140420
- Data Source
  KAKENHI-PROJECT-21790299
[Journal Article] Cancer susceptibility polymorphism of p53 at codon 72 affects phosphorylation and degradation of p53 protein^#.(^#corresponding author)
- Author(s)
  Chikako Ozeki, Tatsuhiro Shibata, Takashi Kohno, Yuichiro Sawai, Koji Okamoto, Jun Yokota, Fumio Tashiro, Seiichi Tanuma, Ryuichi Sakai, Tatsuya Kawase, Issay Kitabayashi, Yoichi Taya, Rieko Ohki.
- Journal Title
  
  Journal of Biological Chemistry (in press.)
- Data Source
  KAKENHI-PROJECT-21790299
[Patent] 移植材料及びその調製方法2015
- Inventor(s)
  大木理恵子、角昭一郎、坂田直昭
- Industrial Property Rights Holder
  大木理恵子、角昭一郎、坂田直昭
- Industrial Property Rights Type
  特許
- Filing Date
  2015-05-22
- Overseas
- Data Source
  KAKENHI-PROJECT-26430133
[Patent] 移植材料及びその調製方法2014
- Inventor(s)
  大木理恵子、角昭一郎、坂田直昭
- Industrial Property Rights Holder
  大木理恵子、角昭一郎、坂田直昭
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-107529
- Filing Date
  2014-05-23
- Data Source
  KAKENHI-PROJECT-26430133
[Patent] shRNA発現ライブラリーの製造方法2010
- Inventor(s)
  大木理恵子
- Industrial Property Rights Holder
  ヒューマンサイエンス振興財団
- Filing Date
  2010-07-05
- Data Source
  KAKENHI-PROJECT-21790299
[Patent] shRNA発現ライブラリーの製造方法2010
- Inventor(s)
  大木理恵子
- Industrial Property Rights Holder
  ヒューマンサイエンス振興財団
- Filing Date
  2010-07-05
- Data Source
  KAKENHI-PROJECT-21790299
[Patent] 医薬組成物、および、腫瘍の治療用医薬剤2010
- Inventor(s)
  大木理恵子、川瀬竜也、柴田龍弘、田矢洋一、油谷浩幸、稲澤譲治、田代文夫
- Industrial Property Rights Holder
  ヒューマンサイエンス振興財団、東京理科大学、東京医科歯科大学
- Filing Date
  2010-02-02
- Overseas
- Data Source
  KAKENHI-PROJECT-21790299
[Patent] 医薬組成物、および、腫瘍の治療用医薬剤2010
- Inventor(s)
  大木理恵子、川瀬竜也、柴田龍弘、田矢洋一、油谷浩幸、稲澤譲治、田代文夫
- Industrial Property Rights Holder
  ヒューマンサイエンス振興財団、東京理科大学、東京医科歯科大学
- Filing Date
  2010-02-02
- Data Source
  KAKENHI-PROJECT-21790299
[Presentation] Elucidation of the role of the p53 pathway in pancreatic neuroendocrine tumor.2022
- Author(s)
  Rieko Ohki
- Organizer
  The 7th JCA-AACR Special Joint Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20F20414
[Presentation] p53-PHLDA3経路はドキソルビシン誘発性心毒性による心機能障害を惹起する．2022
- Author(s)
  野中美希、大島佳織、上園保仁、大木理恵子．
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K06849
[Presentation] PHLDA3は膵島細胞の分化と代謝を制御することで非機能性膵神経内分泌腫瘍の悪性化を抑制する2022
- Author(s)
  チンヨ、大木理恵子
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03523
[Presentation] PHLDA3欠損ブタの作出と異種膵島移植への可能性2022
- Author(s)
  坂田　直昭, 大木　理恵子, 中野　和明, 渡邊　将人,吉松　軍平, 角　昭一郎, 小玉　正太, 長嶋比呂志
- Organizer
  第25回日本異種移植研究会
- Data Source
  KAKENHI-PROJECT-20H03523
[Presentation] p53標的遺伝子p53PAD5は腸管上皮細胞にストレス抵抗性を付与する2022
- Author(s)
  山本樹、青木清乃、高野洋志、山本采佳、山野荘太郎、大島正伸、八尾良司、渡邊利雄、田中知明、大木理恵子
- Organizer
  第35回発癌病理研究会
- Data Source
  KAKENHI-PROJECT-20H03523
[Presentation] p53標的遺伝子p53PAD5は腸管上皮細胞にストレス抵抗性を付与する2022
- Author(s)
  山本樹、青木清乃、高野洋志、山本采佳、山野荘太郎、大島正伸、八尾良司、渡邊利雄、田中知明、大木理恵子
- Organizer
  第35回発癌病理研究会
- Data Source
  KAKENHI-PROJECT-20K07605
[Presentation] p53標的遺伝子p53PAD5は腸管上皮細胞にストレス抵抗性を付与する2022
- Author(s)
  山本樹、青木清乃、高野洋志、山本采佳、山野荘太郎、大島正伸、八尾良司、渡邊利雄、田中知明、大木理恵子
- Organizer
  第35回発癌病理研究会
- Data Source
  KAKENHI-PROJECT-20F20414
[Presentation] IER5-HSF1経路は卵巣がん細胞の増殖と腹膜播種を促進する2022
- Author(s)
  中村萌、植野さやか、山本樹、浅野良則、田端裕子、田中知明、葛山智久、佐谷秀行、大木理恵子
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20F20414
[Presentation] Akt抑制遺伝子であるPHLDA3はドキソルビシンによる心機能障害を惹起する．2022
- Author(s)
  野中美希、田端祐子、佐田あかね、坂口裕紀子、大島佳織、大木理恵子、上園保仁．
- Organizer
  第5回日本腫瘍循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-22K06849
[Presentation] HLDA3 suppresses the malignant progression of non-functional PanNET by regulating cell differentiation and metabolism.2022
- Author(s)
  Yu Chen, Rieko Ohki.
- Organizer
  The 18th International p53 workshop,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20F20414
[Presentation] PHLDA3欠損ブタの作出と異種膵島移植への可能性2022
- Author(s)
  坂田　直昭, 大木　理恵子, 中野　和明, 渡邊　将人,吉松　軍平, 角　昭一郎, 小玉　正太, 長嶋比呂志
- Organizer
  第25回日本異種移植研究会
- Data Source
  KAKENHI-PROJECT-20F20414
[Presentation] p53-PHLDA3経路はドキソルビシン誘発性心毒性による心機能障害を惹起する2022
- Author(s)
  野中美希、大島佳織、上園保仁、大木理恵子
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20F20414
[Presentation] IER5-HSF1経路は卵巣がん細胞の増殖と腹膜播種を促進する2022
- Author(s)
  中村萌、植野さやか、山本樹、浅野良則、田端裕子、田中知明、葛山智久、佐谷秀行、大木理恵子
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03523
[Presentation] PHLDA3は膵島細胞の分化と代謝を制御することで非機能性膵神経内分泌腫瘍の悪性化を抑制する2022
- Author(s)
  チンヨ、大木理恵子
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20F20414
[Presentation] Elucidation of the role of the p53 pathway in pancreatic neuroendocrine tumor.2022
- Author(s)
  Rieko Ohki
- Organizer
  The 7th JCA-AACR Special Joint Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07605
[Presentation] IER5-HSF1経路は卵巣がん細胞の増殖と腹膜播種を促進する2022
- Author(s)
  中村萌、植野さやか、山本樹、浅野良則、田端裕子、田中知明、葛山智久、佐谷秀行、大木理恵子
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K07605
[Presentation] p53-PHLDA3経路はドキソルビシン誘発性心毒性による心機能障害を惹起する2022
- Author(s)
  野中美希、大島佳織、上園保仁、大木理恵子
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03523
[Presentation] Elucidation of the role of the p53 pathway in pancreatic neuroendocrine tumor.2022
- Author(s)
  Rieko Ohki
- Organizer
  The 7th JCA-AACR Special Joint Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03523
[Presentation] PHLDA3 suppresses the malignant progression of non-functional PanNET by regulating cell differentiation and metabolism.2022
- Author(s)
  Yu Chen, Rieko Ohki
- Organizer
  The 18th International p53 workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03523
[Presentation] 分泌性タンパク質p53PAD7とHippoシグナル経路による増殖抑制機構の解明.2020
- Author(s)
  滝川雅大、渡邉祐三、岡部篤史、金田篤志、石川冬木、定家真人、大木理恵子.
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03523
[Presentation] A novel p53 downstream tumor promotion pathway, p53-IER5- HSF1 pathway, that contributes to stress resistance and tumor progression.2020
- Author(s)
  Rieko Ohki
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03523
[Presentation] Akt dysregulation by loss of PHLDA3 is an important determinant of pancreatic neuroendocrine tumor progression.2020
- Author(s)
  Yu Chen, Sadahiro Iwabuchi, Tohru Kiyono, Shigeyuki Magi, Yasuhito Arai, Akihiko Yokoyama, Mariko Okada, Shinichi Hashimoto, Kentaro Semba, Rieko Ohki.
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20F20414
[Presentation] Investigating the crosstalk between MEN1, p53 and Notch reveals biomarkers of formation of primary pancreatic neuroendocrine tumors2020
- Author(s)
  Y. Capodanno, Y. Chen, N. Hiraoka, A. Yokoyama, J. Schrader, R. Ohki.
- Organizer
  the 17th Annual ENETS Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18F18758
[Presentation] Investigating the crosstalk between MEN1, p53 and Notch reveals biomarkers of formation of primary pancreatic neuroendocrine tumors2020
- Author(s)
  Y. Capodanno, Y. Chen, N. Hiraoka, A. Yokoyama, J. Schrader, R. Ohki
- Organizer
  The 17th Annual ENETS conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18F18758
[Presentation] Akt dysregulation by loss of PHLDA3 is an important determinant of pancreatic neuroendocrine tumor progression.2020
- Author(s)
  Yu Chen, Sadahiro Iwabuchi, Tohru Kiyono, Shigeyuki Magi, Yasuhito Arai, Akihiko Yokoyama, Mariko Okada, Shinichi Hashimoto, Kentaro Semba, Rieko Ohki.
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18F18758
[Presentation] Akt dysregulation by loss of PHLDA3 is an important determinant of pancreatic neuroendocrine tumor progression.2020
- Author(s)
  Yu Chen, Sadahiro Iwabuchi, Tohru Kiyono, Shigeyuki Magi, Yasuhito Arai, Akihiko Yokoyama, Mariko Okada, Shinichi Hashimoto, Kentaro Semba, Rieko Ohki.
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03523
[Presentation] p53が制御する新規の神経内分泌腫瘍抑制経路の解明2019
- Author(s)
  大木理恵子
- Organizer
  第78回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18F18758
[Presentation] p53が制御する新規の神経内分泌腫瘍抑制経路の解明2019
- Author(s)
  大木理恵子
- Organizer
  第78回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03587
[Presentation] PHLDA3遺伝子とMEN1遺伝子による膵臓神経内分泌腫瘍抑制機構の解明.2019
- Author(s)
  陳ヨ、大木理恵子.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18F18758
[Presentation] p53が制御する新規の神経内分泌腫瘍抑制経路の解明2019
- Author(s)
  大木理恵子
- Organizer
  第42回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03587
[Presentation] 分泌性タンパク質p53PAD7とHippoシグナル経路による増殖抑制機構の解明2019
- Author(s)
  滝川雅大、大木理恵子
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H03587
[Presentation] 分泌性タンパク質p53PAD7とHippoシグナル経路による増殖抑制機構の解明.2019
- Author(s)
  滝川雅大、大木理恵子.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18F18758
[Presentation] PHLDA3遺伝子とMEN1遺伝子による膵臓神経内分泌腫瘍抑制機構の解明2019
- Author(s)
  陳ヨ、大木理恵子
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H03587
[Presentation] 知られざるp53の肖像～最も有名ながん抑制遺伝子p53の新機能～2019
- Author(s)
  大木理恵子
- Organizer
  第32回モロシヌス研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03587
[Presentation] p53が制御する新規の神経内分泌腫瘍抑制経路の解明2019
- Author(s)
  大木理恵子
- Organizer
  第42回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18F18758
[Presentation] 知られざるp53の肖像～最も有名ながん抑制遺伝子p53の新機能～2019
- Author(s)
  大木理恵子
- Organizer
  第32回モロシヌス研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18F18758
[Presentation] がん抑制遺伝子p53機能喪失とがん微小環境は協調的に胃がん悪性化を促進する2018
- Author(s)
  大木理恵子
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18F18758
[Presentation] 下垂体神経内分泌腫瘍で同定されたがん抑制遺伝子PHLDA3変異の機能解析2018
- Author(s)
  冨永航平、山口陽子、永田喜三郎、大木理恵子
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18F18758
[Presentation] 分泌性p53標的遺伝子p53PAD7の新規受容体の同定と細胞増殖停止機能の解明2018
- Author(s)
  滝川　雅大、石川　冬木、大木　理恵子
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18F18758
[Presentation] がん抑制遺伝子PHLDA3の下垂体腺腫における機能喪失性変異の同定と機能解析2017
- Author(s)
  山口　陽子、冨永　航平、陳　妤、峯岸　舞子、山田正三、大木理恵子
- Organizer
  第27回日本間脳下垂体腫瘍学会
- Place of Presentation
  日経カンファレンスルーム
- Year and Date
  2017-02-24
- Data Source
  KAKENHI-PROJECT-26430133
[Presentation] PHLDA3は下垂体腺腫の新規がん抑制遺伝子である2017
- Author(s)
  陳　妤、峯岸　舞子、斎藤　梢、山田正三、並木秀男、仙波憲太郎、大木理恵子
- Organizer
  第27回日本間脳下垂体腫瘍学会
- Place of Presentation
  日経カンファレンスルーム
- Year and Date
  2017-02-24
- Data Source
  KAKENHI-PROJECT-26430133
[Presentation] IER5 generates a novel hypo-phosphorylated active form of HSF1 and contributes to tumorigenesis2016
- Author(s)
  大木　理恵子
- Organizer
  Tenth AACR-JCA Joint Conference
- Place of Presentation
  アメリカ　ハワイ
- Year and Date
  2016-02-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430133
[Presentation] 8.PH domain-only protein PHLDA3 is a novel p53-regulated repressor of Akt and a novel tumor suppressor of neuroendocrine tumors2016
- Author(s)
  大木理恵子
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-12-02
- Invited
- Data Source
  KAKENHI-PROJECT-26430133
[Presentation] PHLDA3遺伝子は下垂体神経内分泌腫瘍の新規がん抑制遺伝子である2015
- Author(s)
  峯岸舞子、齋藤梢、チンヨ、會田雪絵、川瀬竜也、山田正三、並木秀男、仙波憲太郎、大木理恵子
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-26430133
[Presentation] p53標的遺伝子PAD5は、新規HSF1活性化因子をコードし、がん細胞生存に必須な遺伝子である2015
- Author(s)
  大木　理恵子
- Organizer
  日本癌学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26430133
[Presentation] PH domain-only protein PHLDA3 is a novel p53-regulated repressor of Akt and a novel tumor suppressor of neuroendocrine tumors2015
- Author(s)
  大木　理恵子
- Organizer
  SNUCRI Cancer Symposium
- Place of Presentation
  韓国　広州
- Year and Date
  2015-04-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430133
[Presentation] PH domain-only protein PHLDA3 is a novel p53-regulated repressor of Akt and a novel tumor suppressor of neuroendocrine tumors2015
- Author(s)
  大木理恵子
- Organizer
  2015 SNUCRI Cancer Symposium
- Place of Presentation
  韓国広州
- Year and Date
  2015-04-03
- Invited
- Data Source
  KAKENHI-PROJECT-26430133
[Presentation] Aktの新規抑制因子をコードするPHLDA3遺伝子は神経内分泌腫瘍のがん抑制遺伝子である2015
- Author(s)
  大木　理恵子
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2015-12-04
- Invited
- Data Source
  KAKENHI-PROJECT-26430133
[Presentation] PH domain-only protein PHLDA3 is a novel p53-regulated repressor of Akt and a novel tumor suppressor of neuroendocrine tumors2014
- Author(s)
  大木理恵子
- Organizer
  日韓がんワークショップ
- Place of Presentation
  韓国済州島
- Year and Date
  2014-11-29
- Invited
- Data Source
  KAKENHI-PROJECT-26430133
[Presentation] PH domain-only protein PHLDA3 is a novel p53-regulated repressor of Akt and a novel tumor suppressor of neuroendocrine tumors2014
- Author(s)
  大木理恵子
- Organizer
  日本癌学会年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2014-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-26430133
[Presentation] PH domain-only protein PHLDA3 is a novel p53-regulated repressor of Akt and a novel tumor suppressor of neuroendocrine tumors2014
- Author(s)
  大木理恵子
- Organizer
  16th International p53 workshop
- Place of Presentation
  ストックホルム
- Year and Date
  2014-06-15
- Data Source
  KAKENHI-PROJECT-26430133
[Presentation] Aktの新規抑制因子をコードするPHLDA3遺伝子は神経内分泌腫瘍のがん抑制遺伝子である2014
- Author(s)
  大木理恵子
- Organizer
  第2回日本神経内分泌腫瘍研究会学術集会
- Place of Presentation
  東京都文京区
- Year and Date
  2014-09-20
- Data Source
  KAKENHI-PROJECT-26430133
[Presentation] PH domain-only protein PHLDA3 is a novel p53-regulated repressor of Akt and a novel tumor suppressor of neuroendocrine tumors2014
- Author(s)
  大木理恵子
- Organizer
  日独がんワークショップ
- Place of Presentation
  ドイツベルリン
- Year and Date
  2014-11-15
- Invited
- Data Source
  KAKENHI-PROJECT-26430133
[Presentation] p53 isoform、D 1stTAD-p53 の機能解析及び標的遺伝子の同定2013
- Author(s)
  鈴木詩織、大木理恵子
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  (ポスター発表)
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] PH domain-only protein PHLDA3; a p53-regulated repressor of Akt and a novel tumor suppressor of endocrine tumors2013
- Author(s)
  Rieko Ohki
- Organizer
  The 6th International p63/p73 Workshop
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] 新規p53 標的遺伝子p53PAD1 による糖鎖を介した新たながん抑制経路の解明2013
- Author(s)
  江澤一星、大木理恵子
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  (ポスター発表)
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] がん抑制遺伝子p53 機能喪失を伴った新規悪性胃がんモデルマウスの作製と解析2013
- Author(s)
  大塚旬子、大木理恵子
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  (ポスター発表)
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] PHLDA3 遺伝子とMEN1 遺伝子による膵内分泌腫瘍の抑制機構の解明2013
- Author(s)
  チン・ヨ、大木理恵子
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  (ポスター発表)
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] Akt の新規抑制因子をコードするPHLDA3 遺伝子は内分泌腫瘍のがん抑制遺伝子である2013
- Author(s)
  大木理恵子
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  (口頭発表)
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] がん抑制遺伝子PHLDA3 による新規Akt 抑制メカニズムの解明2013
- Author(s)
  西川雷羅、大木理恵子
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  (ポスター発表)
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] 新規p53 標的遺伝子p53PAD7 の同定と機能解析2013
- Author(s)
  松下周、大木理恵子
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  (ポスター発表)
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] 新規p53 標的遺伝子p53PAD5 はHSF1 活性化を介してがん化を促進する2013
- Author(s)
  浅野良則、大木理恵子
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  (ポスター発表)
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] 新規テロメア結合タンパク質の同定と機能解析～がん化への作用の解明～2013
- Author(s)
  瀧川遥、大木理恵子
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  (ポスター発表)
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] Akt 抑制遺伝子PHLDA3 は膵b細胞の増殖を抑制する2013
- Author(s)
  斉藤梢、大木理恵子
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  (ポスター発表)
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] PHLDA3 遺伝子は下垂体腫瘍の新規がん抑制遺伝子である2013
- Author(s)
  峯岸舞子、大木理恵子
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  (ポスター発表)
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] 新規Akt抑制因子p53PAD9の同定と機能解析2013
- Author(s)
  高野悠平、大木理恵子
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  (ポスター発表)
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] PHLDA3 遺伝子は神経内分泌腫瘍の新規がん抑制遺伝子である2013
- Author(s)
  大木理恵子
- Organizer
  日本遺伝学会第85回大会
- Place of Presentation
  (ワークショップ発表)
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] PH domain-only protein PHLDA3はAktの新規抑制因子であり内分泌腫瘍のがん抑制遺伝子である2012
- Author(s)
  大木理恵子
- Organizer
  平成23年度個体レベルでのがん研究支援活動ワークショップ(招待講演)
- Place of Presentation
  琵琶湖ホテル
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] PH domain-only protein PHLDA3 はAkt の新規抑制因子をコードする内分泌腫瘍の新規がん抑制遺伝子である2012
- Author(s)
  大木理恵子
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  (ワークショップ発表)
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] PH domain-only protein PHLDA3はAktの新規抑制因子であり内分泌腫瘍のがん抑制遺伝子である2012
- Author(s)
  大木理恵子
- Organizer
  がん研セミナー(招待講演)
- Place of Presentation
  公益財団法人がん研究会
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] PH domain-only protein PHLDA3 is a p53-regulated repressor of Akt2012
- Author(s)
  大木理恵子
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  (シンポジウム発表)
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] がん抑制遺伝子PHLDA3と膵内分泌腫瘍2012
- Author(s)
  斉藤梢、大木理恵子
- Organizer
  平成23年度個体レベルでのがん研究支援活動ワークショップ
- Place of Presentation
  琵琶湖ホテル
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] PH domain-only protein PHLDA3 is a p53-regulated repressor of Akt2011
- Author(s)
  Rieko Ohki
- Organizer
  China-Japan Symposium on Cancer Research
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] Novel p53 target gene p53PAD5 is a regulator of HSF12011
- Author(s)
  浅野良則、大木理恵子
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] PH domain-only protein PHLDA3 is a p53-regulated repressor of Akt2011
- Author(s)
  大木理恵子
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  (シンポジウム発表)
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] PH domain-only protein PHLDA3 is a p53-regulated repressor of Akt2011
- Author(s)
  大木理恵子
- Organizer
  第70回日本癌学会学術総会、シンポジウム発表(招待講演)
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] Generation of anti-p53 scFv by immunization with partial peptide using Rapid Antibody Isolation System (RAntIS)2011
- Author(s)
  稲生崇規、大木理恵子
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] Development of candidate anticancer drug targeting p53 regulators Mdm2 and Mdmx2011
- Author(s)
  松本真悠子、大木理恵子
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] PH domain-only protein PHLDA3 ; a p53-regulated repressor of Akt and a novel tumor suppressor of endocrine tumors2011
- Author(s)
  大木理恵子
- Organizer
  日仏がんワークショップ
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] Novel p53 target gene p53PAD1 regulates glycosylation and suppresses tumorigenesis2011
- Author(s)
  江沢一星、大木理恵子
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] PH domain-only protein PHLDA3 is a p53-regulated repressor of Akt2011
- Author(s)
  大木理恵子
- Organizer
  China-Japan Symposium on Cancer Research(招待講演)
- Place of Presentation
  Pattaya Hotel, Shenzhen, China
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] PH domain-only protein PHLDA3; a p53-regulated repressor of Akt and a novel tumor suppressor of endocrine tumors2011
- Author(s)
  大木理恵子
- Organizer
  平成23年度日仏がんワークショップ(招待講演)
- Place of Presentation
  Hotel Mercure, MONTPELLIER, FRANCE
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] Unraveling the molecular mechanism of Akt inhibition by PHLDA32011
- Author(s)
  斉藤梢、大木理恵子
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] A comprehensive screening of shRNAs that regulate p53 activity2010
- Author(s)
  大木理恵子
- Organizer
  AACR-JCA 8th Joint Conference
- Place of Presentation
  国立がん研究センター
- Year and Date
  2010-02-09
- Data Source
  KAKENHI-PROJECT-21790299
[Presentation] 新規癌関連遺伝子の同定による癌化メカニズムの解明2010
- Author(s)
  大木理恵子
- Organizer
  オンコロジーセミナー
- Place of Presentation
  金沢大学がん研究所
- Data Source
  KAKENHI-PROJECT-21790299
[Presentation] A comprehensive screening of shRNAs that regulate p53 activity2010
- Author(s)
  Rieko Ohki, Yosuke Ohsawa, Ryuichi Sakai
- Organizer
  AACR-JCA 8th Joint Conference
- Data Source
  KAKENHI-PROJECT-21790299
[Presentation] 新規癌関連遺伝子の同定による癌化メカニズムの解明2010
- Author(s)
  大木理恵子
- Organizer
  細胞生物学特論セミナー
- Place of Presentation
  早稲田大学大学院・先進理工学研究科
- Data Source
  KAKENHI-PROJECT-21790299
[Presentation] A comprehensive screening of shRNAs that regulate p53 activity2010
- Author(s)
  大木理恵子
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場・リーガロイヤルホテル大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21790299
[Presentation] p53によるAKTシグナルの制御-PH domain-only protein PHLDA3の役割2009
- Author(s)
  大木理恵子
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-21790299
[Presentation] p53によるAKTシグナルの制御-PH domain-only protein PHLDA3の役割2009
- Author(s)
  大木理恵子
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフイコ横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21790299
[Presentation] PH domain-only protein PHLDA3はAktの新規抑制因子である2009
- Author(s)
  大木理恵子
- Organizer
  第13回神経芽腫研究会
- Place of Presentation
  国立がん研究センター
- Year and Date
  2009-08-22
- Data Source
  KAKENHI-PROJECT-21790299
[Presentation] PH domain-only protein PHLDA3はAktの新規抑制因子である2009
- Author(s)
  大木理恵子
- Organizer
  第13回神経芽腫研究会特別講演
- Data Source
  KAKENHI-PROJECT-21790299
[Presentation] PH domain-only protein PHLDA3はAktの新規抑制因子である2009
- Author(s)
  大木理恵子
- Organizer
  第13回神経芽腫研究会
- Place of Presentation
  国立がんセンター
- Year and Date
  2009-08-22
- Data Source
  KAKENHI-PROJECT-21790299
[Presentation] p53によるAKTシグナルの制御-PH domain-only protein PHLDA3の役割2009
- Author(s)
  大木理恵子
- Organizer
  第32回日本分子生物学会年会、ワークショップ発表
- Data Source
  KAKENHI-PROJECT-21790299
[Presentation] PH domain-only protein PHLDA3はAktの新規抑制因子である2009
- Author(s)
  大木理恵子
- Organizer
  第2回シンフォニーシンポジウム
- Place of Presentation
  ホテルメトロポリタンエドモンド
- Year and Date
  2009-09-12
- Data Source
  KAKENHI-PROJECT-21790299
[Presentation] PHドメインのみからなるPHLDA3は、p53の新規標的遺伝子でありAktの新規抑制因子である2009
- Author(s)
  大木理恵子、川瀬竜也、柴田龍弘、堤修一、太田力、市川仁、稲澤譲治、油谷浩幸、田代文夫、田矢洋一
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  (口頭発表)
- Data Source
  KAKENHI-PROJECT-21790299
[Presentation] 新規癌関連遺伝子の同定による癌化メカニズムの解明2009
- Author(s)
  大木理恵子
- Organizer
  第2回シンフォニーシンポジウム
- Data Source
  KAKENHI-PROJECT-21790299
[Presentation] PHドメインのみからなるPHLDA3は、p53の新規標的遺伝子でありAktの新規抑制因子である2009
- Author(s)
  大木理恵子
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21790299
[Presentation] 新規p53標的遺伝子p53PAD1による糖鎖を介した新たながん抑制経路の解明
- Author(s)
  江澤一星、大木理恵子
- Organizer
  第3５回日本分子生物学会年会、ポスター発表
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] Akt抑制遺伝子PHLDA3は膵β細胞の増殖を抑制する
- Author(s)
  斉藤梢、大木理恵子
- Organizer
  第3５回日本分子生物学会年会、ポスター発表
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] がん抑制遺伝子PHLDA3による新規Akt抑制メカニズムの解明
- Author(s)
  西川雷羅、大木理恵子
- Organizer
  第3５回日本分子生物学会年会、ポスター発表
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] PH domain-only protein PHLDA3はAktの新規抑制因子をコードする内分泌腫瘍の新規がん抑制遺伝子である
- Author(s)
  大木理恵子
- Organizer
  第3５回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡
- Invited
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] 新規p53標的遺伝子p53PAD7の同定と機能解析
- Author(s)
  松下周、大木理恵子
- Organizer
  第3５回日本分子生物学会年会、ポスター発表
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] 新規Akt 抑制因子p53PAD9 の同定と機能解析
- Author(s)
  高野悠平、大木理恵子
- Organizer
  第3５回日本分子生物学会年会、ポスター発表
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] 新規p53標的遺伝子p53PAD5はHSF1活性の制御因子である
- Author(s)
  浅野良則、大木理恵子
- Organizer
  第3５回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] p53 isoform、D 1stTAD-p53の機能解析及び標的遺伝子の同定
- Author(s)
  鈴木詩織、大木理恵子
- Organizer
  第3５回日本分子生物学会年会、ポスター発表
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] 癌抑制遺伝子p53を標的とした新規抗癌剤の創製
- Author(s)
  清水未来、大木理恵子
- Organizer
  第3５回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] PHLDA3遺伝子は神経内分泌腫瘍の新規がん抑制遺伝子である
- Author(s)
  大木理恵子
- Organizer
  日本遺伝学会第85回大会、ワークショップ発表
- Place of Presentation
  慶應義塾大学日吉キャンパス第４校舎独立館
- Invited
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] 新規p53標的遺伝子p53PAD1による糖鎖制御を介した新しいがん抑制経路の解明
- Author(s)
  江沢一星、大木理恵子
- Organizer
  第3５回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] Akt抑制遺伝子PHLDA3は新規膵内分泌腫瘍抑制遺伝子である～PHLDA3遺伝子欠損マウスにおける膵ランゲルハンス島細胞の過形成～
- Author(s)
  斉藤梢、大木理恵子
- Organizer
  第3５回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] p53アイソフォームΔ1stTAD-p53標的遺伝子の同定と機能解析
- Author(s)
  鈴木詩織、大木理恵子
- Organizer
  第3５回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] PHLDA3遺伝子とMEN1遺伝子による膵内分泌腫瘍の抑制機構の解明
- Author(s)
  チン・ヨ、大木理恵子
- Organizer
  第3５回日本分子生物学会年会、ポスター発表
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] がん抑制遺伝子p53機能喪失を伴った新規悪性胃がんモデルマウスの作製と解析
- Author(s)
  江沢一星、大木理恵子
- Organizer
  平成24年度個体レベルでのがん研究支援活動ワークショップ
- Place of Presentation
  琵琶湖ホテル
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] Pancreatic islet hyperplasia in mice deficient for PHLDA3, a candidate tumor suppressor gene of endocrine tumors
- Author(s)
  斉藤梢、大木理恵子
- Organizer
  第二回日中がん研究シンポジウム会
- Place of Presentation
  幕張メッセ・国際会議場
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] Development of candidate anticancer drug targeting tumor suppressor p53
- Author(s)
  大木理恵子
- Organizer
  第9回日米癌合同会議
- Place of Presentation
  ハイアットリージェンシー、マウイ　米国
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] Novel p53 target gene p53PAD5 is a regulator of HSF1
- Author(s)
  浅野良則、大木理恵子
- Organizer
  第二回日中がん研究シンポジウム会
- Place of Presentation
  幕張メッセ・国際会議場
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] PHLDA3遺伝子は下垂体腫瘍の新規がん抑制遺伝子である
- Author(s)
  峯岸舞子、大木理恵子
- Organizer
  第3５回日本分子生物学会年会、ポスター発表
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] Aktの新規抑制因子をコードするPHLDA3遺伝子は内分泌腫瘍のがん抑制遺伝子である
- Author(s)
  大木理恵子
- Organizer
  第７２回日本癌学会学術総会、口頭発表
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] PH domain-only protein PHLDA3; a p53-regulated repressor of Akt and a novel tumor suppressor of endocrine tumors
- Author(s)
  大木理恵子
- Organizer
  The 6th International p63/p73 Workshop
- Place of Presentation
  Kazusa Academia Hall
- Invited
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] PH domain-only protein PHLDA3 is a p53-regulated repressor of Akt
- Author(s)
  大木理恵子
- Organizer
  第７１回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌、札幌市教育文化会館、さっぽろ芸文館、札幌市民ホール
- Invited
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] 新規テロメア結合タンパク質の同定と機能解析～がん化への作用の解明～
- Author(s)
  瀧川遥、大木理恵子
- Organizer
  第3５回日本分子生物学会年会、ポスター発表
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] がん抑制遺伝子p53機能喪失を伴った新規悪性胃がんモデルマウスの作製と解析
- Author(s)
  大塚旬子、大木理恵子
- Organizer
  第3５回日本分子生物学会年会、ポスター発表
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] 新規p53標的遺伝子p53PAD5はHSF1活性化を介してがん化を促進する
- Author(s)
  浅野良則、大木理恵子
- Organizer
  第3５回日本分子生物学会年会、ポスター発表
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-23501279
[Presentation] 新規p53標的遺伝子p53PAD5はHSF1活性の制御因子である
- Author(s)
  浅野良則、大木理恵子
- Organizer
  平成24年度がん若手研究者ワークショップ
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23501279

1. 小嶋基寛 (30338470)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. Yamano Shotaro (80614528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. Aoki Kiyono (10383291)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 平岡伸介 (40276217)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 森実千種 (50501871)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 山田正三 (80260131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 清野透 (10186356)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 陳ヨ (40838900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. 山口英樹 (10345035)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 野中美希 (60758077)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 上園保仁 (20213340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. 田端祐子 (90911967)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. CAPODANNO YLENIA

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
14. CHEN YU

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
15. FUJITA Toshitsugu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. FUKUYO Masaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 堺隆一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 白石清之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 木村誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 堤修一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 油谷浩幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 安部良

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 永田喜三郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OHKI Rieko 大木 理恵子

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Co-Researchers

食事療法を用いた副作用のない非機能性の膵臓神経内分泌腫瘍の予防法・治療法の開発Principal Investigator

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がん抑制遺伝子PHLDA3の抗がん剤性心機能障害に対する生理作用の解明

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肝臓におけるタンパク質フコシル化異常による疾患発症機構の解明

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スキルス胃癌と口唇口蓋裂の発症に関わるPLEKHA5の分子機能の解析

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Mechanism of neuroendocrine tumor suppression by the tumor suppressor gene PHLDA3Principal Investigator

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Functional elucidation of the pro-oncogenic p53-IER5 pathway in cancers with wild-type p53

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様々な臓器に発生する神経内分泌腫瘍の全容解明～PHLDA3の機能解析を通じて～Principal Investigator

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ＰＮＥＴ発癌に関するシグナル経路の解明ｐ５３， ＡｋｔとＮｏｔｃｈ経路間の関連Principal Investigator

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Functional analysis of PHLDA3, a repressor of Akt, to elucidate the mechanism of neuroendocrine tumor developmentPrincipal Investigator

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Role of IER5-HSF1 axis in malignant melanoma carcinogenesis

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Functional analysis of PHLDA3, a tumor suppressor gene of neuroendocrine tumorsPrincipal Investigator

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Repression of the Akt pathway by a novel tumor suppressor gene PHLDA3 -towards development of tailor-made therapies-Principal Investigator

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Novel p53 target genes involved in cross talk between oncogenic signals and p53 pathways.Principal Investigator

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OHKI Rieko 大木理恵子

ＰＮＥＴ発癌に関するシグナル経路の解明ｐ５３，　ＡｋｔとＮｏｔｃｈ経路間の関連Principal Investigator