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Kiyono Tohru  清野 透

ORCIDConnect your ORCID iD *help
… Alternative Names

KIYONO Tohru  清野 透

清野 透  キヨノ トオル

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Researcher Number 10186356
Other IDs
External Links
Affiliation (Current) 2025: 公益財団法人佐々木研究所, 附属研究所, 研究員
2025: 国立研究開発法人国立がん研究センター, 先端医療開発センター, プロジェクトリーダー
Affiliation (based on the past Project Information) *help 2020 – 2025: 国立研究開発法人国立がん研究センター, 先端医療開発センター, プロジェクトリーダー
2016 – 2019: 国立研究開発法人国立がん研究センター, 研究所, 分野長
2015: 国立研究開発法人国立がん研究センター, その他部局等, その他
2013: 独立行政法人国立がんセンター, 部長
2012 – 2013: 独立行政法人国立がん研究センター, その他部局等, その他 … More
2011 – 2013: 独立行政法人国立がん研究センター, 研究所, 分野長
2012: 独立行政法人国立がん研究センター, ウイルス部, 部長
2011: 独立行政法人国立がん研究センター, ウィルス部, 部長
2007: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, 研究所・ウイルス部, 部長
2007: National Cancer Center Research Institute, 国立がんセンター・ウイルス部, Senior Researcher
2006 – 2007: 国立がんセンター, ウイルス部, 部長
2006: 国立がんセンター(研究所及び東病院臨床開発センター), ウイルス部, 部長
2004: National Cancer Center Research Institute, Virology Division, Chief, ウイルス部, 部長
2003 – 2004: 国立がんセンター, 研究所, 部長
2003: 国立がんセンター研究所, ウイルス部, 部長
2002: National Cancer Center Research Institute, Virology Division, Chief, ウイルス部, 部長
2001: 愛知県立がんセンター, 腫瘍ウイルス学, 室長
2000 – 2001: 愛知県がんセンター, 腫瘍ウイルス学部, 室長
1999 – 2000: 愛知県がんセンター, ウイルス部, 室長
1999: 愛知県がんセンター研究所, ウイルス部, 室長(研究職)
1995: 愛知県がんセンター, ウイルス部, 室長
1993 – 1994: 愛知県がんセンター, ウイルス部, 主任研究員
1988: 愛知県がんセンター, 研究所・ウィルス部, 研究員
1987: 愛知県がんセンター, ウィルス部, 研究員 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Experimental pathology / Basic Section 50020:Tumor diagnostics and therapeutics-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Tumor biology / General medical chemistry / Carcinogenesis / Biological Sciences / Virology
Except Principal Investigator
Conservative dentistry … More / Surgical dentistry / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Basic Section 54040:Metabolism and endocrinology-related / Basic Section 50010:Tumor biology-related / Orthodontic/Pediatric dentistry / Periodontal dentistry / Virology / Biological Sciences / Experimental pathology Less
Keywords
Principal Investigator
E6 / ヒトパピローマウイルス / E7 / 不死化 / がん幹細胞 / RAS / MYC / 子宮頸がん / TERT / telomerase … More / テロメラーゼ / c-myc / 動物モデル / ヒトパピローマウイルス(HPV) / トランスフォーメーション / ホルモン産生 / 下垂体 / 神経内分泌細胞 / methuosis / 癌 / ヒト正常細胞 / 病理学 / 融合遺伝子 / 末梢型肺腺がん / 幹細胞 / マクロピノサイトーシス / 合成致死 / がん化 / 異種動物 / 再生 / 上皮幹細胞 / 再生医療 / ヒト幹細胞 / PDZ domain / immkortalization / Cancer of uterine cervix / Human Papillomavirus / DLG4 / PSD95 / PDZドメイン / human papillomavirus (HPV) / ヒトパピローマウイルス(MTV) / 膵がん / E2F / DNA-PK / 組み込み / HPV / p16^<INK4a> / 47型ヒトパピローマウイルス / SCIDマウス / 扁平上皮癌 / 疣贅状表皮発育異常症 / DNA複製 / CDC47 / MCM / mRNA差異表示法 / 3β-hydroxysteroid dehydrogenase / 増殖停止 / 接触抑制 / E1A / アデノウイルス / E7遺伝子 / E6遺伝子 / ルシフェラーゼ / トランスアクチベーション / インターフェロン調節因子 … More
Except Principal Investigator
Development / Regeneration / 歯胚 / 歯周病 / 発生 / 再生 / odontoclast / Periodontal ligament / 歯根膜 / 細胞外マトリックス / 移植実験 / 歯小嚢 / 歯周組織 / セメント芽細胞 / セメント質 / 細胞周期 / GFP / 多重ノックアウト / CRISPR-Cas9 / 遺伝子ノックアウト / アデノウイルスベクター / ACTH分泌低下症 / Cushing病 / iPS細胞 / ACTH細胞 / p53 / がん抑制遺伝子 / PHLDA3 / 神経内分泌腫瘍抑制 / Akt / 神経内分泌腫瘍 / がん / emdogain / amelogenin / regeneration / cementoblast / root resorption / 破歯細胞 / 成長因子 / エムドゲイン / アメロゲニン / 再生医学 / 歯根吸収 / elastic fiber / Organogenesis / ligament / Tissue engineering / extracellular matrix / 微小線維 / マイクロフィブリル / マルファン症候群 / 弾性線維 / 器官形成 / 靭帯 / 組織工学 / periodontium / tooth germ / Oxytalan fiber / Extracellular matrix / Dental follicle / モノクロナール抗体 / 細胞分化 / オキシタラン線維 / Telomere / immortalization / Molecular biology / Periodontitis / Progenitor / Cementum / モノクローナル抗体 / テロメア / 不死化 / 前駆体 / 細胞不死化 / 分子生物学 / 前駆体細胞 / 潮基配列 / 相同性 / 塩基配列 / DNA / 疣贅 / いぼ / パピローマ / ウィルス / MMP / Wnt / 顎骨腫瘍 / 骨浸潤 / 歯原性上皮 / Wntシグナル / 歯原性腫瘍 / エナメル上皮腫 / 口腔外科一般 / 中咽頭がん / 口腔がん / ヒトパピローマウイルス / 発がん、 / 口腔がん、 / MCMタンパク / CDC6タンパク / ORCタンパク / 複製開始複合体 / クロマチン免疫沈降法 / グロビン遺伝子 / MCM蛋白 / CDC6蛋白 / ORC蛋白 / Geminin / MCM / CDC6 / CDK / DNA複製開始制御 / ヒト細胞 / DNA障害チェックポイント系 / geminin / ORC / 核アクチン / クロマチンリモデリング複合体 / 発癌 / Cdt1 / Cdk / サイクリン / 染色体不安定性 / 細胞周期制御 / DNA複製 / 細胞接着 / 化学発癌 / 癌治療 / ゲノム医学 / 構造生物学 / シグナル伝達 / ウイルス発癌 / 海外派遣 / 国際学術 Less
  • Research Projects

    (26 results)
  • Research Products

    (68 results)
  • Co-Researchers

    (72 People)
  •  HPVゲノム編集破壊能と腫瘍溶解性の相乗効果を狙ったがん治療アデノベクターの開発Principal Investigator

    • Principal Investigator
      清野 透
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      National Cancer Center Japan
  •  Development of adenovirus vectors enabling selection of multiple gene knockout cells by self-gene editing.

    • Principal Investigator
      中西 友子
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
    • Research Institution
      Juntendo University
  •  Generation of novel human ACTH cells and their application to the treatment of pituitary intractable diseases

    • Principal Investigator
      西山 充
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      Kochi University
  •  Mechanism of neuroendocrine tumor suppression by the tumor suppressor gene PHLDA3

    • Principal Investigator
      Ohki Rieko
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      National Cancer Center Japan
  •  Immortalization of normal human neudoendocrine cellsPrincipal Investigator

    • Principal Investigator
      Kiyono Tohru
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      National Cancer Center Japan
  •  Development of eradicative cancer treatment based on synthetic lethality of induced cancer stem cellsPrincipal Investigator

    • Principal Investigator
      KIYONO Tohru
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor biology
    • Research Institution
      National Cancer Center Japan
  •  Reconstitution of human organs as Xenografts by using in vivo environment of animalsPrincipal Investigator

    • Principal Investigator
      Kiyono Tohru
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General medical chemistry
    • Research Institution
      National Cancer Center Japan
  •  ヒトパピローマウイルス感染による炎症・がん化の動物モデルとがん化の阻止Principal Investigator

    • Principal Investigator
      清野 透
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      National Cancer Center Japan
  •  誘導型人工ヒトがん幹細胞と新規発がん動物モデルによる治療法の開発Principal Investigator

    • Principal Investigator
      清野 透
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Carcinogenesis
    • Research Institution
      National Cancer Center Japan
  •  Molecular analyses on the intercellular signaling relating to the bone destruction of ameloblastoma

    • Principal Investigator
      NAKAMURA Norifumi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Kagoshima University
  •  Molecular analysis of oral carcinogenesis with in vitro multistepcarcinogenesis model

    • Principal Investigator
      NOGUCHI Kazuma
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Hyogo Medical University
  •  子宮頚がん発生におけるHPV DNAの組み込みとE6、E7発現増加機構の解明Principal Investigator

    • Principal Investigator
      清野 透
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  Regeneration of resorbed tooth roots by cementogenesis

    • Principal Investigator
      SUDA Naoto
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Tokyo Medical and Dental University
  •  Development of periodontal ligament regeneration therapy using novel extracellular matrix

    • Principal Investigator
      SAITO Masahiro
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Conservative dentistry
    • Research Institution
      Osaka University
      Kanagawa Dental College
  •  Development of poiodontal regenerative medicine that based on molecular mechanism of cementogenesis.

    • Principal Investigator
      SAITO Masahiro
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Conservative dentistry
    • Research Institution
      Kanagawa Dental College
  •  Analyzing mechanism of oncogenesis by human papillomavirusPrincipal Investigator

    • Principal Investigator
      KIYONO Tohru
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Cancer Center Research Institute
  •  ヒトパピローマウイルスによる発がん機構の解析Principal Investigator

    • Principal Investigator
      清野 透
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Aichi Cancer Center Research Institute
  •  Establishment of regeneration therapy for periodontium based on the molecular mechanisms of cementogenesis

    • Principal Investigator
      SAITO Masahiro
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Kanagawa Dental College
  •  複製複合体の形成とその制御機構の解析

    • Principal Investigator
      藤田 雅俊
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
      Aichi Cancer Center Research Institute
  •  Molecular mechanisms of telomerase activation by human papillomavirus E6Principal Investigator

    • Principal Investigator
      KIYONO Tohru
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Aichi Cancer Center Research Institute
  •  アメリカ大陸を中心としたがん研究先進グループとの研究交流

    • Principal Investigator
      山本 雅
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Field
      Experimental pathology
    • Research Institution
      The University of Tokyo
  •  P1.1mcm3蛋白の機能とヒトパピローマウイルスE6蛋白による修飾Principal Investigator

    • Principal Investigator
      清野 透
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Aichi Cancer Center Research Institute
  •  疣贅状表皮発育異常症に伴う皮膚がんにおけるヒトパピローマウイルス遺伝子発現の解析Principal Investigator

    • Principal Investigator
      清野 透
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Experimental pathology
    • Research Institution
      Aichi Cancer Center Research Institute
  •  細胞接触による増殖停止機構の解析Principal Investigator

    • Principal Investigator
      清野 透
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Experimental pathology
    • Research Institution
      Aichi Cancer Center Research Institute
  •  パピローマウイルスの初期遺伝子産物はインターフェロン調節因子の活性を修飾するか?Principal Investigator

    • Principal Investigator
      清野 透
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Virology
    • Research Institution
      Aichi Cancer Center Research Institute
  •  新型ヒトパピローマウィルスHPV47の分子レベルでの分類学的研究

    • Principal Investigator
      石橋 正英
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Aichi Cancer Center Research Institute

All 2022 2021 2020 2019 2018 2017 2015 2013 2012 2011 2008 2007 2005 2004 2003 Other

All Journal Article Presentation Patent

  • [Journal Article] Puromycin-based purification of cells with high expression of the cytochrome P450 CYP3A4 gene from a patient with drug-induced liver injury (DILI)2022

    • Author(s)
      Miyata, S. Saku, N. Akiyama, S. Javaregowda, P. K. Ite, K. Takashima, N. Toyoda, M. Yura, K. Kimura, T. Nishina, H. Nakazawa, A. Kasahara, M. Nonaka, H. Kiyono, T. Umezawa, A.
    • Journal Title

      Stem Cell Res Ther

      Volume: 13 Issue: 1 Pages: 6-6

    • DOI

      10.1186/s13287-021-02680-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K22670
  • [Journal Article] PHLDA3 Is an Important Downstream Mediator of p53 in Squamous Cell Carcinogenesis2022

    • Author(s)
      Saito Megumi、Sada Akane、Fukuyo Masaki、Aoki Kiyono、Okumura Kazuhiro、Tabata Yuko、Chen Yu、Kaneda Atsushi、Wakabayashi Yuichi、Ohki Rieko
    • Journal Title

      Journal of Investigative Dermatology

      Volume: 142 Issue: 21 Pages: 02271-5

    • DOI

      10.1016/j.jid.2021.09.007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K16707, KAKENHI-PROJECT-19K07494, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20H03523, KAKENHI-PROJECT-20F20414, KAKENHI-PROJECT-18K07080, KAKENHI-PROJECT-20K07605
  • [Journal Article] Three newly established immortalized mesothelial cell lines exhibit morphological phenotypes corresponding to malignant mesothelioma epithelioid, intermediate, and sarcomatoid types, respectively2021

    • Author(s)
      Sato Tatsuhiro、Nakanishi Hayao、Akao Ken、Okuda Maho、Mukai Satomi、Kiyono Tohru、Sekido Yoshitaka
    • Journal Title

      Cancer Cell International

      Volume: 21 Issue: 1 Pages: 546-546

    • DOI

      10.1186/s12935-021-02248-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03527, KAKENHI-PROJECT-19K22670
  • [Journal Article] Restoration of keratinocytic phenotypes in autonomous trisomy-rescued cells.2021

    • Author(s)
      Tanuma-Takahashi A, Inoue M, Kajiwara K, Takagi R, Yamaguchi A, Samura O, Akutsu H, Sago H, Kiyono T, Okamoto A, Umezawa A.
    • Journal Title

      Stem Cell Res Ther

      Volume: 12 Issue: 1 Pages: 476-476

    • DOI

      10.1186/s13287-021-02448-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17317, KAKENHI-PROJECT-19K22670
  • [Journal Article] The transcriptome of wild-type and immortalized corneal epithelial cells.2021

    • Author(s)
      Furuya K, Wu T, Orimoto A, Sugano E, Tomita H, Kiyono T, Kurose T, Takai Y, Fukuda T.
    • Journal Title

      Sci Data.

      Volume: 8(1) Issue: 1 Pages: 126-126

    • DOI

      10.1038/s41597-021-00908-9

    • NAID

      120007175170

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09945, KAKENHI-PROJECT-17K17588, KAKENHI-PLANNED-17H06330, KAKENHI-PROJECT-19H03807, KAKENHI-PROJECT-20H03845, KAKENHI-PROJECT-21K09910, KAKENHI-PROJECT-21K18278, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K22670
  • [Journal Article] Ammonia-based enrichment and long-term propagation of zone I hepatocyte-like cells2021

    • Author(s)
      Tsuneishi Ruri、Saku Noriaki、Miyata Shoko、Akiyama Saeko、Javaregowda Palaksha Kanive、Ite Kenta、Takashima Nagisa、Toyoda Masashi、Kimura Tohru、Kuroda Masahiko、Nakazawa Atsuko、Kasahara Mureo、Nonaka Hidenori、Kamiya Akihide、Kiyono Tohru、Yamauchi Junji、Umezawa Akihiro
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 11381-11381

    • DOI

      10.1038/s41598-021-90708-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-20H04931, KAKENHI-PROJECT-19H03643, KAKENHI-PROJECT-19K22670, KAKENHI-PROJECT-21K19490
  • [Journal Article] Establishment of human airway epithelial cells with doxycycline-inducible cell growth and fluorescence reporters2021

    • Author(s)
      Orimoto Ai、Takahashi Kohei、Imai Masaki、Kiyono Tohru、Kawaoka Yoshihiro、Fukuda Tomokazu
    • Journal Title

      Cytotechnology

      Volume: 73 Issue: 4 Pages: 555-569

    • DOI

      10.1007/s10616-021-00477-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K17588, KAKENHI-PROJECT-21K09910, KAKENHI-PROJECT-19K22670
  • [Journal Article] Combinatorial expression of cell cycle regulators is more suitable for immortalization than oncogenic methods in dermal papilla cells2021

    • Author(s)
      Fukuda Tomokazu、Furuya Kai、Takahashi Kouhei、Orimoto Ai、Sugano Eriko、Tomita Hiroshi、Kashiwagi Sayo、Kiyono Tohru、Ishii Tsuyoshi
    • Journal Title

      iScience

      Volume: 24 Issue: 1 Pages: 101929-101929

    • DOI

      10.1016/j.isci.2020.101929

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09945, KAKENHI-PROJECT-17K17588, KAKENHI-PLANNED-17H06330, KAKENHI-PROJECT-19H03807, KAKENHI-PROJECT-20H03845, KAKENHI-PROJECT-19K22670
  • [Journal Article] Endometrial regeneration with endometrial epithelium: homologous orchestration with endometrial stroma as a feeder2021

    • Author(s)
      Ryo Yokomizo, Yukiko Fujiki, Harue Kishigami, Hiroshi Kishi, Tohru Kiyono, Sanae Nakayama, Haruhiko Sago, Aikou Okamoto, Akihiro Umezawa
    • Journal Title

      Stem Cell Res Ther.

      Volume: 12 Issue: 1 Pages: 130-130

    • DOI

      10.1186/s13287-021-02188-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20J14152, KAKENHI-PROJECT-19K22670
  • [Journal Article] Establishment and genetic characterization of cell lines derived from proliferating nasal polyps and sinonasal inverted papillomas2021

    • Author(s)
      Nukpook, T. Ekalaksananan, T. Kiyono, T. Kasemsiri, P. Teeramatwanich, W. Vatanasapt, P. Chaiwiriyakul, S. Ungarreevittaya, P. Kampan, J. Muisuk, K. Pientong, C.
    • Journal Title

      Sci Rep

      Volume: 11 Issue: 1 Pages: 17100-17100

    • DOI

      10.1038/s41598-021-96444-y

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22670
  • [Journal Article] Efficient immortalization of human dental pulp stem cells with expression of cell cycle regulators with the intact chromosomal condition2020

    • Author(s)
      Orimoto Ai、Kyakumoto Seiko、Eitsuka Takahiro、Nakagawa Kiyotaka、Kiyono Tohru、Fukuda Tomokazu
    • Journal Title

      PLOS ONE

      Volume: 15 Issue: 3 Pages: e0229996-e0229996

    • DOI

      10.1371/journal.pone.0229996

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K17588, KAKENHI-PROJECT-17K07803, KAKENHI-PROJECT-19K22670
  • [Journal Article] E74-Like Factor 3 Is a Key Regulator of Epithelial Integrity and Immune Response Genes in Biliary Tract Cancer2020

    • Author(s)
      Suzuki Masami、Saito-Adachi Mihoko、Arai Yasuhito、Fujiwara Yuko、Takai Erina、Shibata Shinsuke、Seki Masahide、Rokutan Hirofumi、Maeda Daichi、Horie Masafumi、Suzuki Yutaka、Shibata Tatsuhiro、Kiyono Tohru、Yachida Shinichi
    • Journal Title

      Cancer Research

      Volume: 81 Issue: 2 Pages: 489-500

    • DOI

      10.1158/0008-5472.can-19-2988

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07433, KAKENHI-PROJECT-18K07382, KAKENHI-PROJECT-18K07956, KAKENHI-PROJECT-19K22670
  • [Journal Article] Primary and immortalized cell lines derived from the Amami rabbit (Pentalagus furnessi) and evolutionally conserved cell cycle control with CDK4 and Cyclin D1.2020

    • Author(s)
      Orimoto A, Katayama M, Tani T, Ito K, Eitsuka T, Nakagawa K, Inoue-Murayama M, Onuma M, Kiyono T, Fukuda T
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 525 Issue: 4 Pages: 1046-1053

    • DOI

      10.1016/j.bbrc.2020.03.036

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19426, KAKENHI-PROJECT-17K17588, KAKENHI-PROJECT-17H03624, KAKENHI-PROJECT-16H05801, KAKENHI-PROJECT-20K05934, KAKENHI-PUBLICLY-19H04904, KAKENHI-PROJECT-19K22670, KAKENHI-PROJECT-20H00420
  • [Journal Article] Uterine adenomyosis is an oligoclonal disorder associated with KRAS mutations2019

    • Author(s)
      Inoue Satoshi、Hirota Yasushi、Ueno Toshihide、十人省略、Tanaka Yosuke、Sakata Seiji、Takeuchi Kengo、Muraoka Ayako、Osuka Satoko、Saito Tsuyoshi、Oda Katsutoshi、Osuga Yutaka、Terao Yasuhisa、Kawazu Masahito、Mano Hiroyuki
    • Journal Title

      Nature Communications

      Volume: 10 Issue: 1 Pages: 1-13

    • DOI

      10.1038/s41467-019-13708-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07320, KAKENHI-PROJECT-18K09249, KAKENHI-PROJECT-19K07708, KAKENHI-PROJECT-19H03796, KAKENHI-PROJECT-17K07250, KAKENHI-PROJECT-18K19601, KAKENHI-PROJECT-18K16757, KAKENHI-PROJECT-16H04679, KAKENHI-PROJECT-16H05469, KAKENHI-PROJECT-19H03144, KAKENHI-PROJECT-19K22670
  • [Journal Article] Establishment of immortalized primary cell from the critically endangered Bonin flying fox (Pteropus pselaphon)2019

    • Author(s)
      Tani T, Eitsuka T, Katayama M, Nagamine T, Nakaya Y, Suzuki H, Kiyono T, Nakagawa K, Inoue-Murayama M, Onuma M, Fukuda T
    • Journal Title

      PLoS One

      Volume: 14 Issue: 8 Pages: e0221364-e0221364

    • DOI

      10.1371/journal.pone.0221364

    • NAID

      120006863529

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03624, KAKENHI-PROJECT-17K07803, KAKENHI-PROJECT-16H05801, KAKENHI-PUBLICLY-19H04904, KAKENHI-PROJECT-19K22670
  • [Journal Article] Induction of non-apoptotic programmed cell death by oncogenic RAS in human epithelial cells and its suppression by MYC overexpression.2018

    • Author(s)
      Dendo K, Yugawa T, Nakahara T, Ohno SI, Goshima N, Arakawa H, Kiyono T.
    • Journal Title

      Carcinogenesis

      Volume: 39 Issue: 2 Pages: 202-213

    • DOI

      10.1093/carcin/bgx124

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H04701, KAKENHI-PROJECT-26460406
  • [Journal Article] A novel ameloblastoma cell line (AM3)secretes MMP-9 in response to Wnt-3a and induces osteoclastogenesis2013

    • Author(s)
      Toshiro Kibe, Takao Fuchigami, Michiko Kishida, Mikio Iijima, Hiroshi Hijioka, Akihiko Miyawaki, Ichiro Semba, Norifumi Nakamura, Tohoru Kiyono, Shosei Kishida
    • Journal Title

      Oral Surgery Oral Medicine Oral Pathology Oral Radiology & Endodontics

      Volume: 115(6) Pages: 780-788

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592929
  • [Journal Article] A novel ameloblastoma cell line (AM3) secretes MMP-9 in response to Wnt3a and induces osteoclastogenesis.2013

    • Author(s)
      Toshiro Kibe, Takao Fuchigami, Michiko Kishida, Mikio Iijima, Hiroshi Hijioka, Akihiko Miyawaki, Ichiro Senba, tooru Kiyono, Norifumi Nakamura, Shosei Kishida
    • Journal Title

      Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontics

      Volume: 1158 Pages: 780-788

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592929
  • [Journal Article] Establishment of novel ameloblastoma-derived cell line, and the role of Wnt signaling pathway in ameloblastoma.2013

    • Author(s)
      Toshiro Kibe, Takao Fuchigami, Michiko Kishida, Mikio Iijima, Hiroshi Hijioka, Akihiko Miyawaki, Ichiro Senba, tooru Kiyono, Norifumi Nakamura, Shosei Kisida
    • Journal Title

      Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontics

      Volume: 115

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592929
  • [Journal Article] Immortalization and characterization of normal oral epithelial cells without using HPV and SV40 genes2011

    • Author(s)
      Toshiro Kibe, Michiko Kishida, Masayuki Kamino, Mikio Iiima, Lin Clen, Mika Habu, Akihiko Miyawaki, Hiroshi Hijioka, Norifumi Nakamura, Tohru Kiyono, Shosei Kishida
    • Journal Title

      Oral Science International

      Volume: 8(1) Issue: 1 Pages: 20-28

    • DOI

      10.1016/s1348-8643(11)00009-7

    • NAID

      10030270663

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592929, KAKENHI-PROJECT-23659124
  • [Journal Article] Immortalization and characterization of MOE1 cells, normal oral epithelial cell lines without using HPV and SV40 genes-.2011

    • Author(s)
      Toshiro Kibe, Michiko Kidhida, Masayuki Kaimo,Mikiko Iiima, Lin Clen. Mika Habu, Akihiko, Miyawaki, Hiroshi Hijioka, Norifumi Nakamura, Tohru Kiyono, Shosei Kishida
    • Journal Title

      Oral Science International

      Volume: 2 Pages: 20-28

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592929
  • [Journal Article] Characteristic phenotype of immortalized periodontal cells isolated from a Marfan syndrome type I patient.2008

    • Author(s)
      Shiga M, Saito M, Hattori M, Torii C, Kosaki K, Kiyono T, Suda N
    • Journal Title

      Cell Tissue Res 331

      Pages: 461-472

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390552
  • [Journal Article] Characteristic phenotype of immortalized periodontal cells isolated from a Marfan syndrome type I patient2008

    • Author(s)
      Shiga M, Saito M, Hattori M, Torii C, Kosaki K, Kiyono T.
    • Journal Title

      Cell Tissue Res 331(2)

      Pages: 461-72

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390552
  • [Journal Article] Characteristic phenotype of immortalized periodontal cells isolated from a Marfan syndrome type I patient2008

    • Author(s)
      Shiga M, Saito M, Hattori M, Torii C, Kosaki K, Kiyono T, Suda N
    • Journal Title

      Cell Tissue Res 331

      Pages: 461-472

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390552
  • [Journal Article] Establishment of Immortalized Dental Follicle Cells for Generating Periodontal Ligament In Viva2007

    • Author(s)
      T., Yokoi, M., Saito, T., Kiyono, S., Iseki, K., Kosaka, E., Nishida, T., Tsubakimoto, H., Harada, K., Eto, T., Noguchi, T., Thranaka
    • Journal Title

      Cell Tissue Res 327(2)

      Pages: 301-311

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390510
  • [Journal Article] The human papillomavirus E6 and E7 inducible oncogene, hWAPL, exhibits potential as a therapeutic target.2005

    • Author(s)
      Kuroda, M., Kiyono, T, Oikawa, K., Yoshida, K., Mukai, K.
    • Journal Title

      Br.J.Cancer Res. 92

      Pages: 290-293

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14026065
  • [Journal Article] Immortalization of cementoblast progenitor cells with Bmi-1 and TERT.2005

    • Author(s)
      M.Saito, K.Handa, T.Kiyono, S.Hattori, T.Yokoi, T.Tsubakimoto, H.Harada, T.Noguchi, M.Toyoda, S.Sato, T.Teranaka
    • Journal Title

      J Bone Miner Res 20(1)

      Pages: 50-57

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390580
  • [Journal Article] Nishiyama, Y., and Tsurumi T. Inhibition of S-phase cyclin-dependent kinase activity blocks expression of Epstein-Barr virus immediate-early and early genes, preventing viral lytic replication.2004

    • Author(s)
      Kudoh, A., Daikoku, T., Sugaya, Y, Isomura, H., Fujita, M., Kiyono, T.
    • Journal Title

      J.Virol 78

      Pages: 104-115

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14026065
  • [Journal Article] Inhibition of S-phase cyclin-dependent kinase activity blocks expression of Epstein-Barr virus immediate-early and early genes, preventing viral lytic replication.2004

    • Author(s)
      Kudoh, A., Daikoku, T., Sugaya, Y., Isomura, H., Fujita, M., Kiyono, T., Nishiyama, Y., Tsurumi T.
    • Journal Title

      J.Virol. 78

      Pages: 104-115

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390580
  • [Journal Article] Gojo, S., Miyoshi, S., Ita, M., Segawa, K., Ogawa, S., Sakamoto, M., Nakamura, S., and Umezawa, A. Can the life-span of human marrow stromal cells be prolonged by bmi-1, E6, E7, and/or telomerase without affecting cardiomyogenic differentiation?2004

    • Author(s)
      Takeda, Y., Mori, T.Imabayashi, H, Kiyono, T.
    • Journal Title

      J.Gene Med. 6

      Pages: 833-45

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14026065
  • [Journal Article] Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding.2004

    • Author(s)
      Sugimoto N, Tatsumi Y, Tsurumi T, Matsukage A, Kiyono T., Nishitani H, Fujita M.
    • Journal Title

      J Biol Chem 279

      Pages: 19691-19697

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390580
  • [Journal Article] Expression of a novel human gene, h WAPL, is associated with cervical carcinogenesis and tumor progression.2004

    • Author(s)
      Oikawa, K., Ohbayashi, T., Kiyono, T., Nishi, H., Isaka, K., Umezawa, A., Kuroda, M., Mukai, K.
    • Journal Title

      Cancer Res. 64

      Pages: 3545-9

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14026065
  • [Journal Article] Ceramide triggers caspase activation during gamma-radiation-induced apoptosis of human glioma cells lacking functional p53.2004

    • Author(s)
      Hara S, Nakashima S, Kiyono T, Sawada M, Yoshimura S, Iwama T, Sakai N.
    • Journal Title

      Oncol Rep. 12

      Pages: 119-23

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14026065
  • [Journal Article] Can the life-span of human marrow stromal cells be prolonged by bmi-1,E6,E7,and/or telomerase without affecting cardiomyogenic differentiation?2004

    • Author(s)
      Takeda, Y., Mori, T.Imabayashi, H, Kiyono, T., Gojo, S., Miyoshi, S., Ita, M., Segawa, K., Ogawa, S., Sakamoto, M., Nakamura, S., Umezawa, A.
    • Journal Title

      J.Gene Med. 6

      Pages: 833-845

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390580
  • [Journal Article] Identification of a novel telomerase repressor by virtue of its interaction with the human papillomavirus type-16 E6/E6-AP complex.2004

    • Author(s)
      Gewin, L., Myers, H., Kiyono, T., Galloway D.A.
    • Journal Title

      Genes Dev. 18

      Pages: 2269-2282

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390580
  • [Journal Article] Expression of a novel human gene, hWAPL, is associated with cervical carcinogenesis and tumor progression.2004

    • Author(s)
      Oikawa, K., Ohbayashi, T., Kiyono, T., Nishi, H., Isaka, K., Umezawa, A., Kuroda, M., Mukai, K.
    • Journal Title

      Cancer Res. 64

      Pages: 3545-3549

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390580
  • [Journal Article] Molecular mechanisms of TNF-α-Induced ceramide formation in human glioma cells.2004

    • Author(s)
      Sawada, M., Kiyono, T., Nakashima, S., Shinoda, J., Naganawa, T., Hara, S., Iwama, T., Sakai, N.
    • Journal Title

      Cell Death Differ. 11

      Pages: 997-1008

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390580
  • [Journal Article] p53-independent ceramide formation in human glioma cells during γ-radiation-induced apoptosis.2004

    • Author(s)
      Hara, S., Nakashima, S., Kiyono, T., Sawada, M., Yoshimura, S., Yamada, J., Iwama, T., Banno, Y., Shinoda, J., Sakai, N.
    • Journal Title

      Cell Death Differ. 11

      Pages: 853-861

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390580
  • [Journal Article] Ceramide triggers caspase activation during gamma-radiation-induced apoptosis of human glioma cells lacking functional p53.2004

    • Author(s)
      Hara S, Nakashima S, Kiyono T, Sawada M, Yoshimura S, Iwama T, Sakai N.
    • Journal Title

      Oncol Rep. 12

      Pages: 119-123

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390580
  • [Journal Article] Production of prostaglandinE2 via bile acid is enhanced by trypsin and acid in normal human esophageal epithelial cells.2004

    • Author(s)
      Kawabe, A., Shimada, Y., Soma, T., Maeda, M., Itami, A., Kaganoi, J., Kiyono, T., Imamura, M.
    • Journal Title

      Life Sci 75

      Pages: 21-34

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390580
  • [Journal Article] Identification of a novel telomerase repressor that interacts with the human papillomavirus type-16 E6/E6-AP complex.2004

    • Author(s)
      Gewin, L., Myers, H., Kiyono, T., Galloway D.A.
    • Journal Title

      Genes Dev. 18

      Pages: 2269-2282

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14026065
  • [Journal Article] Filament formation of MSF-A, a mammalian septin, in mammary HMEC cells depends on interactions with microtubules.2003

    • Author(s)
      Nagata KI, Kawajiri A, Matsui S, Takagishi M, Shiromizu T, Saitoh N, Izawa I, Kiyono T, Itoh TJ, Hotani H, Inagaki M.
    • Journal Title

      J.Biol.Chem. 278

      Pages: 18538-18543

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390580
  • [Journal Article] Cultured Dental Follicle Cells are able to Produce Cementum Matrix In Vivo2003

    • Author(s)
      M.Saito, K.Handa, M.Yamauchi, T.Kiyono, S.Sato S.Narayanan, T.Ternaka
    • Journal Title

      Archives of Comparative Biology of Tooth Enamel 8

      Pages: 95-97

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390580
  • [Journal Article] Atorvastatin inhibits expression of minichromosome maintenance proteins in vascular muscle cells.2003

    • Author(s)
      Bruemmer, D, Yin, F., Liu, J., Kiyono, T., Fleck, E., van Herle, A., Graf, K, Law, R.E.
    • Journal Title

      Europ.J.Pharmacol 462

      Pages: 15-23

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390580
  • [Journal Article] Peroxisome proliferator-activated receptor inhibits expression of minichromosome maintenance proteins in vascular smooth muscle cells.2003

    • Author(s)
      Bruemmer D, Yin F, Liu J, Berger JP, Kiyono T, Chen J, Fleck E, Van Herle AJ, Forman BM, Law RE.
    • Journal Title

      Mol.Endoclinol. 17

      Pages: 1005-1018

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390580
  • [Journal Article] Maida Y, Kanaya T, Tanaka M, Yatabe N, Inoue M. Successful immortalization of endometrial glandular cells with normal structural and functional characteristics.2003

    • Author(s)
      Kyo S, Nakamura M, Kiyono T
    • Journal Title

      Am J Pathol. 163

      Pages: 2259-69

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14026065
  • [Journal Article] Rapamycin inhibits E2F-dependent expression of minichromosome maintenance proteins in vascular smooth muscle cells.2003

    • Author(s)
      Bruemmer D, Yin F, Liu J, Kiyono T, Fleck E, Van Herle AJ, Law RE.
    • Journal Title

      Biochem.Biophys.Res.Commun. 303

      Pages: 251-258

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390580
  • [Journal Article] Redifferentiation of dedifferentiated chondrocytes and chondrogenesis of human bone marrow stromal cells via chondrpsphere formation with expression profiling by large-scale cDNA analysis.2003

    • Author(s)
      Imabayashi, H., Mori, T., Gojo, S., Kiyono, T., Sugiyama, T., Irie, R., Isogai, T., Hata, J., Toyama, Y., Umezawa, A.
    • Journal Title

      Exp.Cell Res. 288

      Pages: 35-50

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390580
  • [Journal Article] Reactivation of lytic replication from Epstein-Barr virus latently infected B-cells occurs with high S-phase CDK activity while inhibiting celluar DNA replication.2003

    • Author(s)
      Kudoh, A., Fujita, M., Kiyono, T., Kuzushima, K., Sugaya, Y., Izuta, S., Nishiyama, Y., Tsurumi, T.
    • Journal Title

      J.Virol. 77

      Pages: 851-861

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390580
  • [Journal Article] Establishment of latrunculin-A-resistance in HeLa cells by expression of R183A D184A mutant β-actin.2003

    • Author(s)
      Fujita, M., Ichinose, S., Kiyono, T., Tsurumi, T., Omori, A.
    • Journal Title

      Oncogene 22

      Pages: 627-631

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390580
  • [Journal Article] Combination of hTERT and Bmi-1, E6 or E7 induce prolongation of the life span of bone marrow stromal cells from an elderly donor without affecting their neurogenic potential.

    • Author(s)
      Mori T, Kiyono T, Imabayashi H, Takeda Y, Tsuchiya K, Miyoshi S, Makino H, Matsumoto K, Saito H, Ogawa S, Sakamoto M, Hata J, Umezawa A.
    • Journal Title

      Mol Cell Biol. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14026065
  • [Journal Article] Immortalization of Human Fetal Cells : The Life Span of Umbilical-Cord-Blood-derived Cells Can Be Prolonged without Manipulating p16INK4a/RB Braking Pathway.

    • Author(s)
      Terai M, Uyama T, Sugiki T, Li XK, Umezawa A, Kiyono T.
    • Journal Title

      Mol Biol Cell. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14026065
  • [Patent] 特願2018-2304742019

    • Inventor(s)
      片山雅史、清野透、福田智一
    • Industrial Property Rights Holder
      岩手大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Data Source
      KAKENHI-PROJECT-16H04701
  • [Patent] PCT/JP2018/ 0483082019

    • Inventor(s)
      梅澤 明弘、清野 透
    • Industrial Property Rights Holder
      国立成育医療研究センター、国立がん研究センター
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Overseas
    • Data Source
      KAKENHI-PROJECT-16H04701
  • [Patent] 不死化子宮内膜腺上皮細胞株及びその作成2003

    • Inventor(s)
      京 哲, 清野 透, 井上 正樹
    • Industrial Property Rights Holder
      金沢大TLO, 国立がんセ
    • Industrial Property Number
      2003-283911
    • Filing Date
      2003-07-31
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14026065
  • [Presentation] Akt dysregulation by loss of PHLDA3 is an important determinant of pancreatic neuroendocrine tumor progression.2020

    • Author(s)
      Yu Chen, Sadahiro Iwabuchi, Tohru Kiyono, Shigeyuki Magi, Yasuhito Arai, Akihiko Yokoyama, Mariko Okada, Shinichi Hashimoto, Kentaro Semba, Rieko Ohki.
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20H03523
  • [Presentation] ヒト正常細胞の不死化とがん化2019

    • Author(s)
      清野透
    • Organizer
      千葉糖尿病内分泌・骨代謝疾患診療ネットワーク講演会2019
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H04701
  • [Presentation] 至適培養法によるヒト正常上皮細胞の培養とがん研究への応用2019

    • Author(s)
      清野透
    • Organizer
      H30年度北大遺制研シンポジウム「感染・免疫・がん・炎症」
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H04701
  • [Presentation] An efficient method to establish ovarian cancer cell lines recapitulating features of primary tumors2018

    • Author(s)
      Farhana Ishrat Ghani , Kasumi Dendo, Yuki Yoshimatsu, Kazuaki Takahashi, Takashi Kohno, Reiko Watanabe, Hiroshi Yoshida, Masayuki Yoshida, Mitsuya Ishikawa, Tomoyasu Kato and Tohru Kiyono
    • Organizer
      第2回がん三次元培養研究会
    • Data Source
      KAKENHI-PROJECT-16H04701
  • [Presentation] 新規プログラム細胞死メスオーシスによるがん抑制機構2018

    • Author(s)
      清野透
    • Organizer
      北海道大学遺伝子病制御研究所「感染、免疫、がん、炎症」研究集会
    • Data Source
      KAKENHI-PROJECT-16H04701
  • [Presentation] Induction of Macropinocytic Cell Death by Oncogenic RAS in Human Epithelial Cells and Its Suppression by MYC Overexpression2017

    • Author(s)
      Dendo K, Yugawa T, Nakahara T, Ohno SI, Goshima N, Arakawa H, Kiyono T.
    • Organizer
      分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16H04701
  • [Presentation] Recent Progress in human epithelial culture system and its application to cancer research2015

    • Author(s)
      Tohru Kiyono
    • Organizer
      日本癌学会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-10-08
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K15074
  • [Presentation] ヒトパピローマウイルスと子宮頸がん2012

    • Author(s)
      清野透
    • Organizer
      北大遺伝子病制御研究所 研究集会
    • Place of Presentation
      札幌
    • Year and Date
      2012-09-18
    • Data Source
      KAKENHI-PUBLICLY-23114510
  • [Presentation] Roles of HPV E6 and E7 in multistep carcinogenesis2011

    • Author(s)
      清野透
    • Organizer
      第70回日本癌学会総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2011-10-05
    • Data Source
      KAKENHI-PUBLICLY-23114510
  • [Presentation] Establishment and characterization of novel Ameloblastoma-derived cell line.2011

    • Author(s)
      Toshiro Kibe, Michiko Kishida, Hiroshi Hijioka, Akihiko Miyawaki, Mikio IIjima, Masayuki Kamino, Toru Kiyono, Norifumi Nakamura, Shosei Kishida
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23592929
  • [Presentation] ADAMTSL-4とFibrillin-1はオキシタラン線維形成を介して歯根膜発生に協調的に働く2007

    • Author(s)
      高坂一貴、齋藤正寛、筒井仰、眞鍋理一郎、清野透、大島勇人、須田直人、Ganburged Ganjargal、関口清俊、米田俊之
    • Organizer
      第39回日本結合組織学会学術大会
    • Place of Presentation
      東京
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390552
  • [Presentation] I型Marfan症候群患者由来の歯根膜細胞による線維形成の異常2007

    • Author(s)
      志賀百年、齋藤正寛、服部架、小崎健次郎、清野透、須田直人
    • Organizer
      第39回日本結合組織学会学術大会
    • Place of Presentation
      東京
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390552
  • [Presentation] 新規細胞外マトリックスであるADAMTSL-4はマイクロフィブリル形成を介して歯周靭帯形成に関与する2007

    • Author(s)
      斎藤正寛, 高坂一貴, 筒井仰, 眞鍋理一郎, 清野透, 須田直人, Ganburged Ganjargal, 寺中敏夫, 関口清俊, 米田俊之
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390552
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