FUNA Nobutaka 鮒信学

… Alternative Names

Researcher Number	70361574
External Links
Affiliation *help	2010 – 2018 : 静岡県立大学, 食品栄養科学部, 准教授 2009 : 東京大学, 大学院・農学生命科学 2007 – 2009 : The University of Tokyo, 大学院・農学生命科学研究科, 助教 2008 : The University of Tokyo, 大学院農学生命科学研究科, 助教 2006 : 東京大学, 大学院農学生命科学研究科, 助手 2004 – 2005 : 東京大学, 大学院・農学生命科学研究科, 助手
Review Section/Research Field	Principal Investigator Bioproduction chemistry/Bioorganic chemistry / Science and Engineering / Bioorganic chemistry / Applied microbiology Except Principal Investigator Biological Sciences
Keywords	Principal Investigator ポリケタイド / 放線菌 / III型ポリケタイド合成酵素 / ポリケタイド合成酵素 / 微生物 / Oryza sativa / 生合成 / クルクミン / ウコン / ピロン … More Except Principal Investigator 物質生産 / 遺伝子発現制御 / Nocardia farcinia / ゲノム / ゲノム配列 / 放線菌 / Streptomyces griseus / 二次代謝産物 / チトクロームP-450 / Nocardia farcinica / A-ファクター制御カスケード / コンビナトリアル生合成 / Streptomyces avermitilis Less

ものつくりを指向した大腸菌宿主の開発とタンパク質の高生産メカニズムの解明Principal InvestigatorOngoing
- Principal Investigator
  
  鮒信学
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied microbiology
- Research Institution
  University of Shizuoka
芳香族ポリケタイド生合成の理解・分解・再構築Principal InvestigatorOngoing
- Principal Investigator
  
  鮒信学
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  University of Shizuoka
A novel type of polyketide synthase from Saccharopolyspora erythraeaPrincipal Investigator
- Principal Investigator
  
  Funa Nobutaka
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Bioorganic chemistry
- Research Institution
  University of Shizuoka
環状アミン・ポリケタイド融合化合物の生合成研究と微生物生産Principal Investigator
- Principal Investigator
  
  鮒信学
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  University of Shizuoka
未利用遺伝子資源の発掘研究と合成生物学的手法による次世代微生物触媒の開発Principal Investigator
- Principal Investigator
  
  鮒信学
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  University of Shizuoka
Genome mining and microbial production of secondary metabolitesPrincipal Investigator
- Principal Investigator
  
  FUNA Nobutaka
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  University of Shizuoka
  The University of Tokyo
Identification of Novel Polyketide synthase by genome mining approach and its application for polyketide productionPrincipal Investigator
- Principal Investigator
  
  FUNA Nobutaka
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  The University of Tokyo
High efficient production of secondary metabolites on the basis of genomes of Streptomyces
- Principal Investigator
  
  池田治生, 堀之内末治
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kitasato University
  The University of Tokyo
新規P-450のアリルカップリング能を利用した微生物による有用物質生産系の構築Principal Investigator
- Principal Investigator
  
  鮒信学
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  The University of Tokyo

All 2018 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation

[Journal Article] Identification and characterization of bacterial enzymes catalyzing the synthesis of 1,8-dihydroxynaphthalene, a key precursor of dihydroxynaphthalene melanin, from Sorangium cellulosum2018
- Author(s)
  Yusuke Sone, Shuto Nakamura, Makoto Sasaki, Fumihito Hasebe, Seung-Young Kim, and Nobutaka Funa
- Journal Title
  
  Applied and Environmental Microbiology
  
  Volume : 84
- DOI
  10.1128/aem.00258-18
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H05447
[Journal Article] In vitro reconstitution of the catabolic reactions catalyzed by PcaHG, PcaB, and PcaL: The protocatechuate branch of the β-ketoadipate pathway in Rhodococcus jostii RHA12015
- Author(s)
  Yamanashi T, Kim S.-Y., Hara H., and Funa, N.
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume : 79 Pages : 830-835
- DOI
  10.1080/09168451.2014.993915
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-25108721
[Journal Article] Alkyldihydropyrone, a new polyketide synthesized by type III polyketide synthase from Streptomyces reveromyceticus.2014
- Author(s)
  Hongo, Y., Nakamura, T., Takahashi, S., Motoyama, T., Hayashi, T., Hirota, H., Osada, H., and Koshino, H.
- Journal Title
  
  J. Antibiot.
  
  Volume : 49 Pages : 537-542
- DOI
  10.1038/ja.2014.80
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23580125, KAKENHI-PROJECT-24380052, KAKENHI-PUBLICLY-25108721
[Journal Article] Structural basis for cyclization specificity of two Azotobacter type III polyketide synthases: a single amino acid substitution reverses their cyclization specificity2013
- Author(s)
  Satou, R., Miyanaga, A., Ozawa, H., Funa, N., Katuyama, Y., Tanokura, M., Ohnishi, Y., and Horinouchi
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume : 288 Pages : 34146-34157
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25108721
[Journal Article] The O-methyltransferase SrsB catalyzes the decarboxylative methylation of alkylre sorcylic acid during phenolic lipid biosynthesis by Streptomyces griseus2012
- Author(s)
  Nakano, C., Funa, N., Ohnishi, Y., and Horinouchi, S
- Journal Title
  
  Journal of Bacteriology
  
  Volume : 194 Pages : 1544-1551
- DOI
  10.1128/JB.06406-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21688009, KAKENHI-PUBLICLY-23108521
[Journal Article] Fatty Acyl-AMP Ligase Involvement in the Production of Alkylresorcylic Acid by a Myxococcus xanthus Type III Polyketide Synthase2011
- Author(s)
  Hayashi, T., Kitamura, Y., Funa, N., Ohnishi, Y. and Horinouchi, S
- Journal Title
  
  Chembiochem
  
  Volume : 12 Pages : 2166-2176
- DOI
  10.1002/cbic.201100344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21688009, KAKENHI-PUBLICLY-23108521
[Journal Article] Precursordirected biosynthesis of curcumin analogs in Escherichia coll2010
- Author(s)
  Katsuyama, Y., Hirose, Y., Funa, N., Ohnishi, Y., and Horinouchi, S
- Journal Title
  
  Biosci. Biotech. Biochem
  
  Volume : 74 Pages : 641-645
- DOI
  10.1271/bbb.90866
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21688009
[Journal Article] Alkylresorcylic acidsynthesis bytype III polyketide synthase from Oryza sativa2010
- Author(s)
  Matsuzawa, M., Katsuyama, Y., Funa, N., and Horinouchi, S
- Journal Title
  
  Phytochemistry
  
  Volume : 71 Pages : 1059-1067
- DOI
  10.1016/j.phytochem.2010.02.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21688009
[Journal Article] Biosynthesis of Aliphatic Polyketides by Type III Polyketide Synthase and Methyltransferase in Bacillus subtilis2009
- Author(s)
  Nakano, C., Ozawa, H., Akanuma, G., Funa, N., and Horinouchi, S
- Journal Title
  
  J. Bacteriol
  
  Volume : 191 Pages : 4916-4923
- DOI
  10.1128/JB.00407-09
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21688009
[Journal Article] Physically discreteβ-lactamase-type thioesterase catalyzes product release in atrochrysone synthesis by iterative type I polyketide synthase2009
- Author(s)
  Awakawa, T., Yokota, K., Funa, N., Doi, F., Mort, N., Watanabe, H., and Horinouchi, S
- Journal Title
  
  Chem. Biol
  
  Volume : 16 Pages : 613-623
- DOI
  10.1016/j.chembiol.2009.04.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21688009
[Journal Article] Curcuminoid biosynthesis by two type III polyketide synthases in the herb Curcuma longa2009
- Author(s)
  Katsuyama, Y., Kita, T., Funa, N., and Horinouchi, S
- Journal Title
  
  J. Biol. Chem
  
  Volume : 284 Pages : 11160-11170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21688009
[Journal Article] Physically discrete beta-lactamase-type thioesterase catalyzes product release in atrochrysone synthesis by iterative type I polyketide synthase.2009
- Author(s)
  Awakawa, T., Yokota, K., Funa, N., Doi, F., Mori, N., Watanabe, H., Horinouchi, S.
- Journal Title
  
  Chem. Biol. 16
  
  Pages : 613-623
- Data Source
  KAKENHI-PROJECT-17019009
[Journal Article] Curcuminoid biosynthesis by two type III polyketide synthases in the herb Curcuma longa.2009
- Author(s)
  Katsuyama, Y., Kita, T., Funa, N., Horinouchi, S.
- Journal Title
  
  J. Biol. Chem. 284
  
  Pages : 11160-11170
- Data Source
  KAKENHI-PROJECT-17019009
[Journal Article] Biosynthesis of aliphatic polyketides by type III polyketide synthase and methyltransferase in Bacillus subtilis2009
- Author(s)
  Nakano, C., Ozawa, H., Akanuma, G., Funa, N., and Horinouchi, S
- Journal Title
  
  J. Bacteriol PMID 19465653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19780084
[Journal Article] Biosynthesis of aliphatic polyketides by type III polyketide synthase and methyltransferase in Bacillus subtilis.2009
- Author(s)
  Nakano C, Ozawa H, Akanuma G, Funa N, Horinouchi S
- Journal Title
  
  J.Bacteriol. 191
  
  Pages : 4916-4923
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019009
[Journal Article] Physically discrete beta-lactamase-type thioesterase catalyzes product release in atrochrysone synthesis by iterative type I polyketide synthase.2009
- Author(s)
  Awakawa T, Yokota K, Funa N, Doi F, Mori N, Watanabe H, Horinouchi S
- Journal Title
  
  Chem.Biol. 161
  
  Pages : 613-623
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019009
[Journal Article] Curcuminoid biosynthesis by two type III polyketide synthases in the herb Curcuma longa.2009
- Author(s)
  Katsuyama Y, Kita T, Funa N, Horinouchi S
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages : 11160-11170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019009
[Journal Article] Biosynthesis of aliphatic polyketides by type III polyketide synthase and methyltransferase in Bacillus subtilis.2009
- Author(s)
  Nakano, C., Ozawa, H., Akanuma, G., Funa, N., Horinouchi, S.
- Journal Title
  
  J. Bacteriol 191
  
  Pages : 4916-4923
- Data Source
  KAKENHI-PROJECT-17019009
[Journal Article] Curcuminoid biosynthesis by two type III polyketide synthases in the herb Curcuma longa2009
- Author(s)
  Katsuyama, Y., Kita, T., Funa, N., and Horinouchi, S
- Journal Title
  
  J. Biol. Chem 284
  
  Pages : 11160-11170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19780084
[Journal Article] Phenolic lipids synthesized by type III polyketide synthase confer penicillinresistance on Streptomyces griseus.2008
- Author(s)
  Masanori Funabashi
- Journal Title
  
  J. Biol. Chem. 283
- Data Source
  KAKENHI-PROJECT-17019009
[Journal Article] Direct transfer of starter substrates from type I fatty acid synthase to type III polyketide synthases in phenolic lipid synthesis.2008
- Author(s)
  Miyanaga, A., Funa, N., Awakawa, T., Horinouchi, S.
- Journal Title
  
  Proc. Natl. Acad. Sci. 105
  
  Pages : 871-876
- Data Source
  KAKENHI-PROJECT-17019009
[Journal Article] Phenolic lipids synthesized by type III polyketide synthase confer penicillin resistance on Streptomyces griseus.2008
- Author(s)
  Funabashi, M., Funa, N., Horinouchi, S.
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages : 13983-13991
- Data Source
  KAKENHI-PROJECT-17019009
[Journal Article] Production of curcuminoids by Escherichia coli containing an artificial biosynthesis pathway.2008
- Author(s)
  Katsuyama, Y., Matsuzawa, M., Funa, N., Horinouchi, S.
- Journal Title
  
  Microbiology 154
  
  Pages : 2620-2628
- Data Source
  KAKENHI-PROJECT-17019009
[Journal Article] Direct transfer of starter substrates from type I fatty acid synthase to type III polyketide synthases in phenolic lipid synthesis2008
- Author(s)
  Miyanaga, A., Funa, N., Awakawa, T., and Horinouchi, S
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 105
  
  Pages : 871-876
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19780084
[Journal Article] Phenolic Lipids Synthesized by Type III Polyketide Synthase Confer Penicillin Resistance on Streptomyces griseus2008
- Author(s)
  Funabashi, M., Funa, N., and Horinouchi, S
- Journal Title
  
  . Biol. Chem 283
  
  Pages : 13983-13991
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19780084
[Journal Article] In vitro synthesis of curcuminoids by type III polyketide synthase from Oryza sativa2007
- Author(s)
  Katsuyama, Y., Matsuzawa, M., Funa, N., and Horinouchi, S
- Journal Title
  
  J. Biol. Chem 282
  
  Pages : 37702-37709
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19780084
[Journal Article] Pentaketide resorcylic acid synthesis by type III polyketide synthase from Neurospora crassa2007
- Author(s)
  Funa, N., Awakawa, T., and Horinouchi, S
- Journal Title
  
  J. Biol. Chem 282
  
  Pages : 14476-14481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19780084
[Journal Article] Pentaketide resorcylic acid synthesis by type III polyketide synthase from Neurospora crassa.2007
- Author(s)
  Nobutaka Funa
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages : 14476-14481
- Data Source
  KAKENHI-PROJECT-17019009
[Journal Article] Phenolic lipid synthesis by type III polyketide synthases is essential for cyst formation in Azotobacter vinelandii.2006
- Author(s)
  Nobutaka Funa
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 103
  
  Pages : 6356-6361
- Data Source
  KAKENHI-PROJECT-17019009
[Journal Article] Phenolic lipid synthesis by type III polyketide synthases is essential for cyst formation in Azotobacter vinelandii.2006
- Author(s)
  Nobutaka Funa
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 103(in press)
- Data Source
  KAKENHI-PROJECT-17019009
[Journal Article] Biosynthesis of hexahydroxyperylenequinone melanin via oxidative aryl coupling by cytochrome P-450 in Streptomyces griseus.2005
- Author(s)
  Nobutaka Funa
- Journal Title
  
  J.Bacteriol. 187
  
  Pages : 8149-8155
- Data Source
  KAKENHI-PROJECT-17019009
[Journal Article] A novel uinone-forming monooxygenase family involved in modification of aromatic polyketides.2005
- Author(s)
  Nobutaka Funa
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages : 14514-14523
- Data Source
  KAKENHI-PROJECT-17019009
[Journal Article] A novel quinone-forming monoxygenase family involved in modification of aromatic polyketides2005
- Author(s)
  N.Funa, M.Funabashi, E.Yoshimura, S.Horinouchi
- Journal Title
  
  Journal of Biological Chemistry 280巻15号
  
  Pages : 14514-14523
- Data Source
  KAKENHI-PROJECT-16780081
[Journal Article] Efficient production of (2S)-flavanones by Escherichia coli containing an artificial biosynthetic gene cluster2005
- Author(s)
  I.Miyahisa, M.Kaneko, N.Funa, Y.Ohnishi, H.Kawasaki, H.Kojima, S.Horinouchi
- Journal Title
  
  Applied Microbiology and Biotechnology 68巻4号
  
  Pages : 498-504
- Data Source
  KAKENHI-PROJECT-16780081
[Journal Article] Biosynthesis of hexahydroxyperlyenequinone melanin via oxidative aryl coupling by cytochrome P-450 in Streptomyces griseus2005
- Author(s)
  N.Funa, M.Funabashi, Y.Ohnishi, S.Horinouchi
- Journal Title
  
  Journal of Bacteriology 187巻23号
  
  Pages : 8149-8155
- Data Source
  KAKENHI-PROJECT-16780081
[Journal Article] Combinatorial biosynthesis of flavones and flavonols in Escherichia coli
- Author(s)
  I.Miyahisa, N.Funa, Y.Ohnishi, S.Martens, T.Moriguchi, S.Horinouchi
- Journal Title
  
  Applied Microbiology and Biotechnology (in press)
- Data Source
  KAKENHI-PROJECT-16780081
[Presentation] 粘液細菌Sorangium cellulosum由来1,8-DHN合成酵素群の機能解析2018
- Author(s)
  曽根祐輔、中村修人、長谷部文人、金承榮、鮒信学
- Organizer
  日本農芸化学会
- Data Source
  KAKENHI-PUBLICLY-17H05447
[Presentation] Saccharopolyspora erythraea由来FabB/F様ポリケタイド合成酵素のin vitro解析2016
- Author(s)
  天野結香子、鮒信学
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-26660097
[Presentation] Microbial production of curcuminoids.2015
- Author(s)
  Nobutaka Funa
- Organizer
  5th International Conference on Biomolecular Engineering
- Place of Presentation
  Texas, USA
- Year and Date
  2015-01-15
- Invited
- Data Source
  KAKENHI-PUBLICLY-25108721
[Presentation] 粘性細菌Sorangium cellulosum 由来新規メラニン生合成酵素2015
- Author(s)
  曽根祐輔、中村修人、金承榮、鮒信学
- Organizer
  2015年度日本農芸化学会
- Place of Presentation
  岡山
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PUBLICLY-25108721
[Presentation] Saccharopolyspora erythraea由来の新規タイプのポリケタイド合成酵素の機能解析2014
- Author(s)
  天野結香子、金承榮、鮒信学
- Organizer
  2014年度日本放線菌学会大会
- Place of Presentation
  筑波
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-26660097
[Presentation] 環状アミン・ポリケタイド融合化合物の生合成研究と微生物生産2014
- Author(s)
  鮒信学
- Organizer
  生物活性物質構造多様性創出システムの解明と制御、第8回公開シンポジウム
- Place of Presentation
  東京
- Year and Date
  2014-12-05
- Data Source
  KAKENHI-PUBLICLY-25108721
[Presentation] 環状アミン・ポリケタイド融合化合物の生合成研究と微生物生産2014
- Author(s)
  鮒信学
- Organizer
  生物活性物質構造多様性創出システムの解明と制御、第7回公開シンポジウム
- Place of Presentation
  東京
- Year and Date
  2014-06-21
- Data Source
  KAKENHI-PUBLICLY-25108721
[Presentation] III型ポリケタイド合成酵素DpyAによるラクトン化の分子機構の解明2014
- Author(s)
  谷美生夏、相澤光輝、金承榮、高橋俊二、長田裕之、鮒信学
- Organizer
  2014年度日本放線菌学会大会
- Place of Presentation
  筑波
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PUBLICLY-25108721
[Presentation] 大腸菌における生体内malonyl-CoA量に寄与する因子のスクリーニング2014
- Author(s)
  山本聡、山梨智也、鮒信学
- Organizer
  日本農芸化学会中部支部第 171 回例会
- Place of Presentation
  名古屋
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PUBLICLY-25108721
[Presentation] Acetyl-CoA carboxylaseの発現によるクルクミンの微生物生産2014
- Author(s)
  曽根祐輔、山梨智也、大石奈穂美、天野結香子、金承榮、鮒信学
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PUBLICLY-25108721
[Presentation] 脂肪酸合成経路の遮断による一次代謝産物の生産能の強化2014
- Author(s)
  大石奈穂美、山梨智也、曽根祐輔、田辺友紀、山本聡、金承榮、鮒信学
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PUBLICLY-25108721
[Presentation] Streptomyces reveromyceticus由来の新規III型ポリケタイド合成酵素の機能解析2013
- Author(s)
  相澤光輝、小野寺渓斗、高橋俊二、小下雅比古、金承榮、長田裕之、鮒信学
- Organizer
  2013年度日本放線菌学会大会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PUBLICLY-25108721
[Presentation] 環状アミン・ポリケタイド融合化合物の生合成研究と微生物生産2013
- Author(s)
  鮒信学
- Organizer
  生合成マシーナリー: 生物活性物質構造多様性創出システムの解明と制御、第6回公開シンポジウム
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PUBLICLY-25108721
[Presentation] 環状アミン・ポリケタイド融合化合物の生合成研究と微生物生産2013
- Author(s)
  鮒信学
- Organizer
  生合成マシーナリー: 生物活性物質構造多様性創出システムの解明と制御、第5回公開シンポジウム
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PUBLICLY-25108721
[Presentation] Biosynthesis of Aromatic Polyketide by Type III Polyketide Synthases2012
- Author(s)
  Nobutaka Funa
- Organizer
  The International Conference of Natural Product Biosynthesis 2012
- Place of Presentation
  Hyogo, Japan
- Data Source
  KAKENHI-PUBLICLY-23108521
[Presentation] 未利用遺伝子資源の発掘と合成生物学的手法による微生物触媒の開発2012
- Author(s)
  鮒信学
- Organizer
  生物活性物質構造多様性創出システムの解明と制御、第4回公開シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PUBLICLY-23108521
[Presentation] Rhodococcus jostii RHAl株におけるβ-ケトアジピン酸経路の新規バイパス経路の解析2011
- Author(s)
  山梨智也、原啓文、鮒信学
- Organizer
  日本農芸化学会2012年度大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21688009
[Presentation] Microbial production of plant polyketides by utilizing diversereactions of type III polyketide synthases2011
- Author(s)
  Nobutaka Funa
- Organizer
  IUMS(International Congress of Bacteriology and Applied Microbiology)
- Place of Presentation
  Hokkaido, Japan
- Year and Date
  2011-09-09
- Data Source
  KAKENHI-PROJECT-21688009
[Presentation] Microbial production of plant polyketides by utilizing diverse reactions of type III polyketide synthases2011
- Author(s)
  Nobutaka Funa
- Organizer
  International Congress of Bacteriology and Applied Microbiology
- Place of Presentation
  札幌コンベンションセンター(北海道)(招待講演)
- Year and Date
  2011-09-09
- Data Source
  KAKENHI-PROJECT-21688009
[Presentation] Microbial production of plant polyketides by utilizing diverse reactions of type III polyketide synthases2011
- Author(s)
  Nobutaka Funa
- Organizer
  International Congress of Bacteriology and Applied Microbiology
- Place of Presentation
  札幌コンベンションセンター(北海道)(招待講演)
- Year and Date
  2011-09-09
- Data Source
  KAKENHI-PUBLICLY-23108521
[Presentation] 「組換え大腸菌と組換え酵母の共培養による非天然型イソフラボンの生産」2010
- Author(s)
  勝山陽平、松井美里、鮒信学、大西康夫、堀之内末治
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21688009
[Presentation] ウコン由来クルクミン合成酵素(CURS)の結晶構造解析2010
- Author(s)
  勝山陽平、宮園健一、鮒信学、田之倉優、大西康夫、堀之内末治
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21688009
[Presentation] Myxococcus xanthus由来のfattyacyl-AMP ligase依存的priming機構を持ったIII型ポリケタイド合成酵素の機能解析2010
- Author(s)
  林貴之、鮒信学、大西康夫、堀之内末治
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21688009
[Presentation] A β-lactamase-type thioesterase responsible for product release in polyketide biosynthesis2010
- Author(s)
  Nobutaka Funa
- Organizer
  2010 RIKEN Chemical Biology International Symposium
- Place of Presentation
  埼玉
- Year and Date
  2010-10-26
- Data Source
  KAKENHI-PROJECT-21688009
[Presentation] Curcuminoid synthesis by type III polyketide synthases and their application to microbial production of plant polyketides2010
- Author(s)
  Nobutaka Funa
- Organizer
  Pacifichem 2010
- Place of Presentation
  Hawaii, USA
- Year and Date
  2010-12-15
- Data Source
  KAKENHI-PROJECT-21688009
[Presentation] Aβ-lactamase-type thioesterase responsible for product release in polyketide biosynthesis2010
- Author(s)
  Nobutaka Funa
- Organizer
  2010 RIKEN Chemical Biology International Symposium
- Place of Presentation
  Saitama, Japan
- Year and Date
  2010-10-26
- Data Source
  KAKENHI-PROJECT-21688009
[Presentation] Actinoplanes missouriensis由来の新規テルペノイドーポリケタイド融合化合物合成に関わる遺伝子クラスターの機能解析2010
- Author(s)
  淡川孝義、鮒信学、藤田信之、早川正幸、大西康夫、堀之内末治
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21688009
[Presentation] 窒素固定細菌由来III型ポリケタイド合成酵素の環化機構の解析2010
- Author(s)
  佐藤龍太朗、宮永顕正、小沢弘樹、鮒信学、宮園健一、田之倉優、大西康夫、堀之内末治
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21688009
[Presentation] 1型ポリケタイド合成酵素から生成物を解離するβ-1actamse型チオエステラーゼの機能解析2010
- Author(s)
  淡川孝義、横田康介、鮒信学、大西康夫、堀之内末治
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21688009
[Presentation] Curcuminoid synthesis by type III polyketide synthases and their application to microbial production of plant polyketides2010
- Author(s)
  Nobutaka Funa
- Organizer
  Pacifichem 2010
- Place of Presentation
  ハワイ州、アメリカ
- Year and Date
  2010-12-15
- Data Source
  KAKENHI-PROJECT-21688009
[Presentation] イネOryza sativa のIII 型ポリケタイド合成酵素の網羅的解析2009
- Author(s)
  鮒信学、松沢未来、勝山陽平、堀之内末治
- Organizer
  日本農芸化学会2009年度大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19780084
[Presentation] Myxococcus xanthus 由来のIII 型ポリケタイド合成酵素のfatty acyl AMPligase 依存的priming 機構2009
- Author(s)
  林貴之、北村裕太、鮒信学、堀之内末治
- Organizer
  日本農芸化学会2009年度大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19780084
[Presentation] 枯草菌Bacillus subtilis 由来III型ポリケタイド合成酵素BcsAの過剰発現株により生産される脂溶性ポリケタイドの構造解析2009
- Author(s)
  仲野千秋、赤沼元気、鮒信学、堀之内末治
- Organizer
  日本農芸化学会2009年度大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19780084
[Presentation] ウコン由来のIII 型ポリケタイド合成酵素によるクルクミンの生合成2009
- Author(s)
  勝山陽平、喜多智子、鮒信学、堀之内末治
- Organizer
  日本農芸化学会2009年度大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19780084
[Presentation] イネOryza sarivaのIII型ポリケタイド合成酵素の網羅的機能解析2009
- Author(s)
  鮒信学
- Organizer
  日本農芸化学会
- Place of Presentation
  福岡
- Year and Date
  2009-03-29
- Data Source
  KAKENHI-PROJECT-19780084
[Presentation] Alkylresorcylic acid を合成するイネ由来III 型ポリケタイド合成酵素の機能解析2009
- Author(s)
  松沢未来、勝山陽平、鮒信学、堀之内末治
- Organizer
  日本農芸化学会2009年度大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19780084
[Presentation] Combinatorial biosynthesis of plant medicinal polyketides in microorganisms2009
- Author(s)
  Nobutaka Funa
- Organizer
  25^<th> Naito Conference
- Place of Presentation
  Hokkaido, Jappan
- Year and Date
  2009-09-11
- Data Source
  KAKENHI-PROJECT-21688009
[Presentation] クルクミノイド合成を司るイネ由来III型ポリケタイド合成酵素の発見2008
- Author(s)
  松沢未来、勝山陽平、鮒信学、堀之内末治
- Organizer
  日本農芸化学会2008年度大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19780084
[Presentation] イネ由来のクルクミノイド合成酵素(CUS)の機能解析2008
- Author(s)
  勝山陽平、松沢未来、鮒信学、堀之内末治
- Organizer
  日本農芸化学会2008年度大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19780084
[Presentation] Aspergillus terreus 由来I 型ポリケタイド合成酵素によるemodin合成2008
- Author(s)
  淡川孝義、鮒信学、堀之内末治
- Organizer
  日本農芸化学会2008年度大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19780084
[Presentation] 脂溶性ポリケタイド生合成におけるI型脂肪酸合成酵素からIII型ポリケタイド合成酵素への基質の受け渡し2008
- Author(s)
  宮永顕正、鮒信学、堀之内末治
- Organizer
  日本農芸化学会2008年度大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19780084

1. 池田治生 (90159632)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
2. 堀之内末治 (80143410)

# of Collaborated Projects : 2results

# of Collaborated Products : 9results
3. 石川淳 (40202957)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
4. 長谷部文人 (30781801)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
5. AMANO Yukako

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
6. HIROTA Hiroshi

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
7. 本山高幸

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
8. 高橋俊二

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

FUNA Nobutaka 鮒 信学

鮒 伸学 フナ ノブタカ

Research Projects

Research Products

Co-Researchers

ものつくりを指向した大腸菌宿主の開発とタンパク質の高生産メカニズムの解明Principal InvestigatorOngoing

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芳香族ポリケタイド生合成の理解・分解・再構築Principal InvestigatorOngoing

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A novel type of polyketide synthase from Saccharopolyspora erythraeaPrincipal Investigator

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環状アミン・ポリケタイド融合化合物の生合成研究と微生物生産Principal Investigator

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未利用遺伝子資源の発掘研究と合成生物学的手法による次世代微生物触媒の開発Principal Investigator

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Genome mining and microbial production of secondary metabolitesPrincipal Investigator

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Identification of Novel Polyketide synthase by genome mining approach and its application for polyketide productionPrincipal Investigator

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High efficient production of secondary metabolites on the basis of genomes of Streptomyces

Principal Investigator

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新規P-450のアリルカップリング能を利用した微生物による有用物質生産系の構築Principal Investigator

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[Journal Article] Identification and characterization of bacterial enzymes catalyzing the synthesis of 1,8-dihydroxynaphthalene, a key precursor of dihydroxynaphthalene melanin, from Sorangium cellulosum2018

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DOI

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[Journal Article] In vitro reconstitution of the catabolic reactions catalyzed by PcaHG, PcaB, and PcaL: The protocatechuate branch of the β-ketoadipate pathway in Rhodococcus jostii RHA12015

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DOI

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[Journal Article] Alkyldihydropyrone, a new polyketide synthesized by type III polyketide synthase from Streptomyces reveromyceticus.2014

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[Journal Article] Structural basis for cyclization specificity of two Azotobacter type III polyketide synthases: a single amino acid substitution reverses their cyclization specificity2013

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[Journal Article] The O-methyltransferase SrsB catalyzes the decarboxylative methylation of alkylre sorcylic acid during phenolic lipid biosynthesis by Streptomyces griseus2012

Author(s)

FUNA Nobutaka 鮒信学

鮒伸学フナノブタカ