Yukihiro Asami 浅見行弘

… Alternative Names

ASAMI Yukihiro 浅見行弘

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Researcher Number	70391844
Other IDs	https://orcid.org/0000-0003-1821-9169
Affiliation (Current)	2025: 北里大学, 感染制御科学府, 教授
Affiliation (based on the past Project Information) *help	2019 – 2023: 北里大学, 感染制御科学府, 教授 2020: 北里大学, 感染制御科学府, 特任准教授 2018: 北里大学, 感染制御科学府, 特任准教授 2017: 北里大学, 感染制御科学府, 特任講師 2016: 北里大学, 感染制御科学府, 講師 2016: 北里大学, 大学院感染制御科学府, 助教 2015: 北里大学, 感染制御科学府, 助教
Review Section/Research Field	Principal Investigator Basic Section 47050:Environmental and natural pharmaceutical resources-related / Natural medicines Except Principal Investigator Basic Section 56020:Orthopedics-related / Bioorganic chemistry
Keywords	Principal Investigator 薬剤耐性因子 / 生物活性物質 / 微生物薬品学 / 抗生物質 / 天然物化学 / 微生物由来 / MRSA / 天然活性物質 / メタロ-β-ラクタマーゼ / 耐性克服活性 … More / メロペネム / スクリーニング / 微生物培養液 / 有機合成化学 / ケミカルバイオロジー / 生物有機化学 / 病原性細菌 / 標的分子 / T3SS / Ⅲ型分泌装置 … More Except Principal Investigator 骨吸収 / 石灰化 / 低中分子化合物 / 受容体 / Wnt / BMP / 骨形成 / グラム陰性病原細菌 / 酵素阻害物質 / 薬剤耐性克服 / メタロ-β-ラクタマーゼ / 薬剤耐性菌 / スクリーニング / 微生物化学 / 天然物化学 / 薬剤耐性 / 抗生物質 Less

Discovery of microorganism-derived anti-MRSA therapeutic seed compounds that inhibit drug resistance factorsPrincipal Investigator
- Principal Investigator
  
  Asami Yukihiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Kitasato University
Analysis of molecular mechanisms of bone formation and heterotopic calcification
- Principal Investigator
  
  Katagiri Takenobu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Saitama Medical University
Development of novel metallo-beta-lactamase inhibitors based on the discovery of new natural productsPrincipal Investigator
- Principal Investigator
  
  Asami Yukihiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Kitasato University
Chemical biology analysis of type III secretion system inhibitors and discovery of novel natural ligandsPrincipal Investigator
- Principal Investigator
  
  Asami Yukihiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Natural medicines
- Research Institution
  Kitasato University
Search for metallo-beta-lactamase inhibitors produced by microorganisms
- Principal Investigator
  
  Shiomi Kazuro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Kitasato University

All 2024 2023 2022 2021 2015 Other

All Journal Article Presentation Patent

[Journal Article] The potentiation activity of β-lactam by phomoidrides and oxasetin against methicillin-resistant Staphylococcus aureus2024
- Author(s)
  Honsho Masako、Kimishima Aoi、Ikeda Akari、Iwatsuki Masato、Nonaka Kenichi、Matsui Hidehito、Hanaki Hideaki、Asami Yukihiro、Sunazuka Toshiaki
- Journal Title
  
  The Journal of Antibiotics
  
  Volume: 77 Issue: 3 Pages: 185-188
- DOI
  10.1038/s41429-023-00691-2
- Data Source
  KAKENHI-PROJECT-21K06616
[Journal Article] A new tetronomycin analog, broad‐spectrum and potent antibiotic against drug‐resistant Gram‐positive bacteria2024
- Author(s)
  Kimishima Aoi、Tsuruoka Iori、Tsutsumi Hayama、Honsho Masako、Honma Sota、Matsui Hidehito、Sugamata Miho、Wasuwanich Paul、Inahashi Yuki、Hanaki Hideaki、Asami Yukihiro
- Journal Title
  
  Chemistry & Biodiversity
  
  Volume: 21 Issue: 2
- DOI
  10.1002/cbdv.202301834
- Data Source
  KAKENHI-PROJECT-22K15305, KAKENHI-PROJECT-21K06616
[Journal Article] Synergistic effect of secondary metabolites isolated from <i>Pestalotiopsis</i> sp. FKR-0115 in overcoming β-lactam resistance in MRSA2023
- Author(s)
  Taba Kanako、Honsho Masako、Asami Yukihiro、Iwasaki Hiromu、Nonaka Kenichi、Watanabe Yoshihiro、Iwatsuki Masato、Matsui Hidehito、Hanaki Hideaki、Teruya Toshiaki、Ishii Takahiro
- Journal Title
  
  J. Gen. Appl. Microbiol.
  
  Volume: 69 Issue: 4 Pages: 234-238
- DOI
  10.2323/jgam.2023.06.001
- ISSN
  0022-1260, 1349-8037
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K05806, KAKENHI-PROJECT-21K06616
[Journal Article] Rediscovery of tetronomycin as a broad-spectrum and potent antibiotic against drug-resistant Gram-positive bacteria2023
- Author(s)
  Aoi Kimishima, Iori Tsuruoka, Hiroki Kanto, Hayama Tsutsumi, Naoaki Arima, Kazunari Sakai, Miho Sugamata, Hidehito Matsui, Yoshihiro Watanabe, Masato Iwatsuki, Masako Honsho, Kamrun Naher, Yuki Inahashi, Hideaki Hanaki, Yukihiro Asami
- Journal Title
  
  ACS Omega
  
  Volume: 8 Issue: 12 Pages: 11556-11563
- DOI
  10.1021/acsomega.3c00651
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06616, KAKENHI-PROJECT-22K15305
[Journal Article] A new isomaneonene derivative from the red alga Laurencia cf. mariannensis2022
- Author(s)
  Takahiro Ishii, Arisu Tahara, Kanako Taba, Masato Iwatsuki, Masako Honsho, Yukihiro Asami, Kenichi Nonaka, Hideaki Hanaki, Toshiaki Teruya
- Journal Title
  
  Journal of Asian Natural Products Research
  
  Volume: - Issue: 7 Pages: 1-7
- DOI
  10.1080/10286020.2022.2130266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06616, KAKENHI-PROJECT-22K05806
[Patent] 新規メタロ-β-ラクタマーゼ阻害剤2015
- Inventor(s)
  大村智、塩見和朗、浅見行弘、野中健一、鹿島由衣、花木秀明
- Industrial Property Rights Holder
  北里大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-061943
- Filing Date
  2015-03-25
- Data Source
  KAKENHI-PROJECT-26450142
[Presentation] 薬剤耐性グラム陽性細菌に対する広域かつ強力な抗菌活性を示すテトロノマイシンの再発見2023
- Author(s)
  鶴岡伊織, 君嶋葵, 菅藤裕貴, 堤隼馬, 有馬直明, 酒井一成, 菅又美穂, 松井秀仁, 渡邊善洋, 岩月正人, 本庄雅子, Naher Kamrun, 稲橋佑起, 花木秀明, 浅見行弘
- Organizer
  日本農芸化学会2023年度大会 2023年3月15日
- Data Source
  KAKENHI-PROJECT-21K06616
[Presentation] 抗薬剤耐性グラム陽性細菌物質テトロノマイシンの再発見とその作用機序解析2023
- Author(s)
  鶴岡伊織, 君嶋葵, 菅藤裕貴, 堤隼馬, 有馬直明, 酒井一成, 菅又美穂, 松井秀仁, 渡邊善洋, 岩月正人, 本庄雅子, Naher Kamrun, 本間颯太, 稲橋佑起, 花木秀明, 浅見行弘
- Organizer
  第65回天然有機化合物討論会　2023年9月4日
- Data Source
  KAKENHI-PROJECT-21K06616
[Presentation] メタロ-β-ラクタマーゼ阻害物質ODTAAの構造活性相関研究2021
- Author(s)
  中里貴々、池田朱里、冨山昴大、池谷佳紀、本庄雅子、浅見行弘、廣瀬友靖、砂塚敏明
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18K06733
[Presentation] New metallo-beta-lactamase inhibitor produced by Paecilomyces sp. FKI-68012015
- Author(s)
  K. Shiomi, Y. Kashima, T. Suga, Y. Asami, T. Ishii, M. Iwatsuki, K. Nonaka, H. Matsui, H. Hanaki, S. Omura
- Organizer
  ICAAC/ICC 2015
- Place of Presentation
  サンディエゴ（米国）
- Year and Date
  2015-09-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450142
[Presentation] 微生物代謝産物からのmetallo-β-lactamase阻害剤の探索
- Author(s)
  鹿島由衣、須賀拓弥、浅見行弘、岩月正人、野中健一、大村智、塩見和朗
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山大学津島キャンパス（岡山市北区）
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-26450142

1. Shiomi Kazuro (40235502)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. MATSUMOTO Atsuko (20300759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. HANAKI Hideaki (60286747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. Katagiri Takenobu (80245802)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 自見英治郎 (40276598)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 君嶋葵 (10832404)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. 堤隼馬

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yukihiro Asami 浅見 行弘

ASAMI Yukihiro 浅見 行弘

Research Projects

Research Products

Co-Researchers

Discovery of microorganism-derived anti-MRSA therapeutic seed compounds that inhibit drug resistance factorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of molecular mechanisms of bone formation and heterotopic calcification

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel metallo-beta-lactamase inhibitors based on the discovery of new natural productsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Chemical biology analysis of type III secretion system inhibitors and discovery of novel natural ligandsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Search for metallo-beta-lactamase inhibitors produced by microorganisms

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The potentiation activity of β-lactam by phomoidrides and oxasetin against methicillin-resistant Staphylococcus aureus2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A new tetronomycin analog, broad‐spectrum and potent antibiotic against drug‐resistant Gram‐positive bacteria2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synergistic effect of secondary metabolites isolated from <i>Pestalotiopsis</i> sp. FKR-0115 in overcoming β-lactam resistance in MRSA2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Rediscovery of tetronomycin as a broad-spectrum and potent antibiotic against drug-resistant Gram-positive bacteria2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A new isomaneonene derivative from the red alga Laurencia cf. mariannensis2022

Author(s)

Journal Title

DOI

Data Source

[Patent] 新規メタロ-β-ラクタマーゼ阻害剤2015

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

[Presentation] 薬剤耐性グラム陽性細菌に対する広域かつ強力な抗菌活性を示すテトロノマイシンの再発見2023

Author(s)

Organizer

Data Source

[Presentation] 抗薬剤耐性グラム陽性細菌物質テトロノマイシンの再発見とその作用機序解析2023

Author(s)

Organizer

Data Source

[Presentation] メタロ-β-ラクタマーゼ阻害物質ODTAAの構造活性相関研究2021

Author(s)

Organizer

Yukihiro Asami 浅見行弘

ASAMI Yukihiro 浅見行弘