Mizoguchi Hiroyuki 溝口博之

… Alternative Names

MIZOGUCHI Hiroyuki 溝口博之

溝口博之ミゾグチヒロユキ

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Researcher Number	70402568
Other IDs
Affiliation (Current)	2025: 名古屋大学, 医学部附属病院, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 名古屋大学, 医学部附属病院, 准教授 2016 – 2019: 名古屋大学, 環境医学研究所, 講師 2009 – 2016: Nagoya University, 環境医学研究所, 助教 2007: Nagoya University, 環境医学研究所, 助教 2006: 金沢大学, 自然科学研究科, 助手
Review Section/Research Field	Principal Investigator Complex systems / Biological pharmacy / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Basic Section 51010:Basic brain sciences-related / Medium-sized Section 10:Psychology and related fields / Experimental psychology / Basic / Social brain science / Pharmacology in pharmacy Except Principal Investigator General pharmacology / Basic Section 48030:Pharmacology-related / Endocrinology
Keywords	Principal Investigator 意思決定 / 島皮質 / 覚せい剤 / オレキシン / 動機づけ / 意志力 / 神経回路 / DREADD / MMP / 薬物依存 … More / 喜び / 食行動 / 大脳基底核 / リスク志向 / モデルフリー / モデルベース / ギャンブル障害 / 行動選択 / モデルフリー・モデルベース / ＤＲＥＡＤＤ / 精神疾患 / 報酬予測誤差 / ニコチン受容体 / ニコチン / 線条体 / ギャンブル試験 / 薬物依存症 / 苔状線維 / 海馬 / キンドリング / てんかん / BDNF / TIMP / ドパミントランスポーター / メタンフェタミン / ドパミン受容体 / ドパミン / tissue inhibitor of matrix metallopreoteinase / matrix metalloproteinase … More Except Principal Investigator 動物モデル / 統合失調症 / メタンフェタミン / 意思決定 / 覚せい剤 / 神経科学 / 薬物依存 / 認知機能 / 神経スパイン / twinfilin-1 / リーリン / 抗精神病薬 / Ｒhoキナーゼ / ROCK2阻害薬 / Fasudil / 抗精神病作用 / Rhoキナーゼ / DREADDシステム / 神経回路 / 大脳基底核 / 島皮質 / 薬理学 / 脳神経疾患 / ギャンブルテスト / 薬物依存症 / D-セリン / 炎症性サイトカイン / アストログリア / 神経－グリア相互作用 / エンドサイトーシス / IFITM3 / polyI:C / 神経-グリア相互作用 / アストログリア細胞 / 神経発達障害 / カルシニューリン / 行動学試験 / タンパク / 遺伝子改変マウス / タンパク質 / 遺伝子 / 脳・神経 / 内分泌学 / プロテインキナーゼA / ドーパミンD1受容体 / モルヒネ / ニコチン / 認知症 / 覚せい剤精神病 / ドーパミン / プラスミン / 組織プラスミノーゲン活性化因子 Less

Study on the regulation mechanism of neural spine morphology and cognitive function by twinfilin-1
- Principal Investigator
  
  山田清文
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Fujita Health University
  Nagoya University
Development of new behavioral systems for investigating the mechanism of pleasure in food eatingPrincipal Investigator
- Principal Investigator
  
  Mizoguchi Hiroyuki
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Nagoya University
Genomic analysis-based neuropharmacological study on basal ganglia-thalamocortical circuits for new drug discovery in schizophrenia
- Principal Investigator
  
  Yamada Kiyofumi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Nagoya University
Research on decision-making and reinforcement learning in animal model of gambling disorder using a mixture of model-free and model-based reinforcement learning taskPrincipal Investigator
- Principal Investigator
  
  Mizoguchi Hiroyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 10:Psychology and related fields
- Research Institution
  Nagoya University
不確実な状況下における報酬動機づけメカニズムとオレキシン神経活動Principal Investigator
- Principal Investigator
  
  溝口博之
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Nagoya University
Neural basis of risky decision-making: Behavior, neural manipulation, computational approachesPrincipal Investigator
- Principal Investigator
  
  Mizoguchi Hiroyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51010:Basic brain sciences-related
- Research Institution
  Nagoya University
オレキシン神経特異的機能操作による動機づけ神経回路の解明と意志力検証技術の開発Principal Investigator
- Principal Investigator
  
  溝口博之
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Nagoya University
Research on neural circuit in decision-making by using cell- and projection-specific manner of chemogenetics and computational approachPrincipal Investigator
- Principal Investigator
  
  Mizoguchi Hiroyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Basic / Social brain science
- Research Institution
  Nagoya University
A novel behavioral task for investigating a mixture of model-free and model-based reinforcement learning in rodentsPrincipal Investigator
- Principal Investigator
  
  Mizoguchi Hiroyuki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Experimental psychology
- Research Institution
  Nagoya University
DREADDシステムと計算論的手法を用いた近視眼的意思決定の追究Principal Investigator
- Principal Investigator
  
  溝口博之
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Nagoya University
Study on the neuronal circuit and molecular mechanis underlying decision-making and its application for drug development
- Principal Investigator
  
  Yamada Kiyofumi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
Effect of nicotine on reward-based decision-making in healthy and methamphetamine-treated ratPrincipal Investigator
- Principal Investigator
  
  Mizoguchi Hiroyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Nagoya University
Effect of drugs of abuse on reward-based decision-making in rodents
- Principal Investigator
  
  YAMADA Kiyofumi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
Research for reward-basis decision making in drug abuse-dependent ratPrincipal Investigator
- Principal Investigator
  
  MIZOGUCHI Hiroyuki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagoya University
Functional analysis of IFITM3 in neurodevelopmental impairments
- Principal Investigator
  
  YAMADA Kiyofumi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
精神機能に及ぼす甲状腺ホルモン作用におけるRCAN/カルシニューリン系の役割
- Principal Investigator
  
  KANOU Yasuhiko
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Nagoya University
Comprehensive research of MMP gene in an animal model of epileptic seizurePrincipal Investigator
- Principal Investigator
  
  MIZOGUCHI Hiroyuki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagoya University
ANALYSES OF DYNAMIC CHANGES AND THE FUNCTION OF TISSUE PLASMINOGEN ACTIVATOR IN ANIMAL MODELS OF DOPAMINE-RELATED MENTAL DISORDERS
- Principal Investigator
  
  YAMADA Kiyofumi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
薬物依存の形成機序の解明-マトリクスメタロプロテアーゼの関与-Principal Investigator
- Principal Investigator
  
  溝口博之
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagoya University
  Kanazawa University

[Journal Article] Retrospective Analysis of Neutrophil-to-Lymphocyte Ratio in Patients with Melanoma Who Received Ipilimumab Monotherapy or Ipilimumab in Combination with Nivolumab in Japan2023
- Author(s)
  Matsumura Yuka、Kawarada Yuki、Matsuo Momo、Yokota Kenji、Mizoguchi Hiroyuki、Akiyama Masashi、Yamada Kiyofumi
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 46 Issue: 3 Pages: 427-431
- DOI
  10.1248/bpb.b22-00750
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2023-03-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19749
[Journal Article] Rho kinase inhibitors ameliorate cognitive impairment in a male mouse model of methamphetamine-induced schizophrenia2023
- Author(s)
  Liao Jingzhu、Dong Geyao、Zhu Wenjun、Wulaer Bolati、Mizoguchi Hiroyuki、Sawahata Masahito、Liu Yue、Kaibuchi Kozo、Ozaki Norio、Nabeshima Toshitaka、Nagai Taku、Yamada Kiyofumi
- Journal Title
  
  Pharmacological Research
  
  Volume: 194 Pages: 106838-106838
- DOI
  10.1016/j.phrs.2023.106838
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19749, KAKENHI-PROJECT-23K27360
[Journal Article] Inhibition of Rho-kinase ameliorates decreased spine density in the medial prefrontal cortex and methamphetamine-induced cognitive dysfunction in mice carrying schizophrenia-associated mutations of the Arhgap10 gene.2023
- Author(s)
  Tanaka R, Liao J, Hada K, Mori D, Nagai T, Matsuzaki T, Nabeshima T, Kaibuchi K, Ozaki N, Mizoguchi H, Yamada K.
- Journal Title
  
  Pharmacological Research
  
  Volume: 187 Pages: 106589-106589
- DOI
  10.1016/j.phrs.2022.106589
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19749, KAKENHI-PROJECT-20H03428, KAKENHI-PROJECT-19K07384, KAKENHI-PROJECT-20K07082, KAKENHI-PROJECT-23K27360
[Journal Article] New Strategies for the Treatment of Neuropsychiatric Disorders Based on Reelin Dysfunction2022
- Author(s)
  Tsuneura Yumi、Nakai Tsuyoshi、Mizoguchi Hiroyuki、Yamada Kiyofumi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 3 Pages: 1829-1829
- DOI
  10.3390/ijms23031829
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K21811, KAKENHI-PROJECT-19H03532, KAKENHI-PROJECT-20H03428
[Journal Article] Antipsychotic-like effects of fasudil, a Rho-kinase inhibitor, in a pharmacologic animal model of schizophrenia.2022
- Author(s)
  Takase S, Liao J, Liu Y, Tanaka R, Miyagawa Y, Sawahata M, Sobue A, Mizoguchi H, Nagai T, Kaibuchi K, Ozaki N, Yamada K.
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 15;931 Pages: 175207-175207
- DOI
  10.1016/j.ejphar.2022.175207
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19749, KAKENHI-PROJECT-20K16488, KAKENHI-PROJECT-20H03428, KAKENHI-PROJECT-20K07082
[Journal Article] Mice with exonic RELN deletion identified from a patient with schizophrenia have impaired visual discrimination learning and reversal learning in touchscreen operant tasks2022
- Author(s)
  Liao Jingzhu、Dong Geyao、Wulaer Bolati、Sawahata Masahito、Mizoguchi Hiroyuki、Mori Daisuke、Ozaki Norio、Nabeshima Toshitaka、Nagai Taku、Yamada Kiyofumi
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 416 Pages: 113569-113569
- DOI
  10.1016/j.bbr.2021.113569
- NAID
  120007190677
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21811, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-19H03532, KAKENHI-PROJECT-20H03428, KAKENHI-PROJECT-20K07082
[Journal Article] Alzheimer’s Disease Animal Models: Elucidation of Biomarkers and Therapeutic Approaches for Cognitive Impairment2021
- Author(s)
  Nakai Tsuyoshi、Yamada Kiyofumi、Mizoguchi Hiroyuki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 11 Pages: 5549-5549
- DOI
  10.3390/ijms22115549
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K21811, KAKENHI-PROJECT-19H03532
[Journal Article] Microglial gene signature reveals loss of homeostatic microglia associated with neurodegeneration of Alzheimer’s disease2021
- Author(s)
  Sobue Akira、Komine Okiru、Hara Yuichiro、Endo Fumito、Mizoguchi Hiroyuki、Watanabe Seiji、Murayama Shigeo、Saito Takashi、Saido Takaomi C.、Sahara Naruhiko、Higuchi Makoto、Ogi Tomoo、Yamanaka Koji
- Journal Title
  
  Acta Neuropathologica Communications
  
  Volume: 9 Issue: 1 Pages: 111111-111111
- DOI
  10.1186/s40478-020-01099-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06896, KAKENHI-PROJECT-19K21811, KAKENHI-PROJECT-20K16488, KAKENHI-PUBLICLY-19H05017, KAKENHI-PUBLICLY-19H05437, KAKENHI-PROJECT-19H03532, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17H04986
[Journal Article] Analysis of Reelin signaling and neurodevelopmental trajectory in primary cultured cortical neurons with RELN deletion identified in schizophrenia2021
- Author(s)
  Tsuneura Yumi、Sawahata Masahito、Itoh Norimichi、Miyajima Ryoya、Mori Daisuke、Kohno Takao、Hattori Mitsuharu、Sobue Akira、Nagai Taku、Mizoguchi Hiroyuki、Nabeshima Toshitaka、Ozaki Norio、Yamada Kiyofumi
- Journal Title
  
  Neurochemistry International
  
  Volume: 144 Pages: 104954-104954
- DOI
  10.1016/j.neuint.2020.104954
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07051, KAKENHI-PROJECT-19K21811, KAKENHI-PROJECT-20K16488, KAKENHI-PUBLICLY-19H05017, KAKENHI-PROJECT-19H03532, KAKENHI-PROJECT-20H03428, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-20H03384, KAKENHI-PROJECT-19K07384, KAKENHI-PROJECT-21K19342
[Journal Article] Mice carrying a schizophrenia-associated mutation of the Arhgap10 gene are vulnerable to the effects of methamphetamine treatment on cognitive function: association with morphological abnormalities in striatal neurons2021
- Author(s)
  Hada K, Wulaer B, Nagai T, Itoh N, Sawahata M, Sobue A, Mizoguchi H, Mori D, Kushima I, Nabeshima T, Ozaki N, Yamada K.
- Journal Title
  
  Mol Brain
  
  Volume: 14(1) Issue: 1 Pages: 21-21
- DOI
  10.1186/s13041-021-00735-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K21811, KAKENHI-PROJECT-20K16488, KAKENHI-PUBLICLY-19H05017, KAKENHI-PROJECT-19H03532, KAKENHI-PROJECT-20H03428, KAKENHI-PROJECT-20K07082
[Journal Article] Touchscreen-based location discrimination and paired associate learning tasks detect cognitive impairment at an early stage in an App knock-in mouse model of Alzheimer's disease2020
- Author(s)
  Saifullah MAB, Komine O, Dong Y, Fukumoto K, Sobue A, Endo F, Saito T, Saido TC, Yamanaka K, Mizoguchi H.
- Journal Title
  
  Mol Brain.
  
  Volume: 13(1) Issue: 1 Pages: 147-147
- DOI
  10.1186/s13041-020-00690-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K21811, KAKENHI-PROJECT-20K16488, KAKENHI-PUBLICLY-19H05017, KAKENHI-PROJECT-19H03532
[Journal Article] REM sleep?active MCH neurons are involved in forgetting hippocampus-dependent memories2019
- Author(s)
  Izawa Shuntaro、Chowdhury Srikanta、Miyazaki Toh、Mukai Yasutaka、Ono Daisuke、Inoue Ryo、Ohmura Yu、Mizoguchi Hiroyuki、Kimura Kazuhiro、Yoshioka Mitsuhiro、Terao Akira、Kilduff Thomas S.、Yamanaka Akihiro
- Journal Title
  
  Science
  
  Volume: 365 Issue: 6459 Pages: 1308-1313
- DOI
  10.1126/science.aax9238
- NAID
  120006777541
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07545, KAKENHI-PROJECT-18K11031, KAKENHI-PROJECT-19K21811, KAKENHI-PROJECT-18KK0223, KAKENHI-PUBLICLY-19H04976, KAKENHI-PUBLICLY-19H05017, KAKENHI-PROJECT-18H02477, KAKENHI-PROJECT-19H03532, KAKENHI-PROJECT-18J21663, KAKENHI-PROJECT-18J21665, KAKENHI-PROJECT-19J15425, KAKENHI-PROJECT-16H06276, KAKENHI-PUBLICLY-18H05124, KAKENHI-PUBLICLY-19H05016, KAKENHI-PROJECT-18H02523
[Journal Article] Nicotine and varenicline ameliorate changes in reward-based choice strategy and altered decision-making in methamphetamine-treated rats.2019
- Author(s)
  Mizoguchi H, Wang T, Kusaba M, Fukumoto K, Yamada K.
- Journal Title
  
  Behav Brain Res.
  
  Volume: 359 Pages: 935-941
- DOI
  10.1016/j.bbr.2018.06.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H06053, KAKENHI-PROJECT-16H03303, KAKENHI-PROJECT-17H04031
[Journal Article] Methamphetamine use causes cognitive impairment and altered decision-making.2019
- Author(s)
  Mizoguchi H, Yamada K.
- Journal Title
  
  Neurochem Int.
  
  Volume: 124 Pages: 106-113
- DOI
  10.1016/j.neuint.2018.12.019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H06053, KAKENHI-PROJECT-16H03303, KAKENHI-PROJECT-17H04031
[Journal Article] Physiological centers of decision-making: manipulation of neural activity in insular cortex by AAV2019
- Author(s)
  溝口博之, 山田清文.
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 153 Issue: 5 Pages: 224-230
- DOI
  10.1254/fpj.153.224
- NAID
  130007649350
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K21811, KAKENHI-PUBLICLY-19H05017, KAKENHI-PROJECT-19H03532
[Journal Article] Preproenkephalin-expressing ventral pallidal neurons control inhibitory avoidance learning. 2019 (in press)2019
- Author(s)
  Macpherson T, Mizoguchi H, Yamanaka A, Hikida T
- Journal Title
  
  Neurochem Int
  
  Volume: 126 Pages: 11-18
- DOI
  10.1016/j.neuint.2019.02.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0223, KAKENHI-PLANNED-16H06568, KAKENHI-PUBLICLY-17H05563, KAKENHI-PUBLICLY-17H06053, KAKENHI-PUBLICLY-18H05124, KAKENHI-PROJECT-16H03303, KAKENHI-PROJECT-18H02523, KAKENHI-PROJECT-18H02542, KAKENHI-PROJECT-16K14579, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K21811, KAKENHI-PUBLICLY-19H05017, KAKENHI-PROJECT-19H03532
[Journal Article] Maternal separation as a risk factor for aggravation of neuropathic pain in later life in mice.2019
- Author(s)
  Mizoguchi H, Fukumoto K, Sakamoto G, Jin S, Toyama A, Wang T, Suzumura A, Sato J.
- Journal Title
  
  Behav Brain Res.
  
  Volume: 359 Pages: 942-949
- DOI
  10.1016/j.bbr.2018.06.015
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H06053, KAKENHI-PROJECT-16H03303
[Journal Article] ギャンブル障害の現状と薬剤師の役割2018
- Author(s)
  溝口博之, 山田清文.
- Journal Title
  
  医薬ジャーナル
  
  Volume: 54(4) Pages: 1037-1040
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H06053
[Journal Article] ギャンブル障害の現状と薬剤師の役割.2018
- Author(s)
  溝口博之, 山田清文.
- Journal Title
  
  医薬ジャーナル
  
  Volume: 54(4) Pages: 1037-1040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H03303
[Journal Article] Disrupted axon-glia interactions at the paranode in myelinated nerves cause axonal degeneration and neuronal cell death in the aged Caspr mutant mouse shambling.2016
- Author(s)
  Takagishi Y, Katanosaka K, Mizoguchi H, Murata Y.
- Journal Title
  
  Neurobiology of Aging
  
  Volume: 43 Pages: 34-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K13505
[Journal Article] Disrupted axon-glia interactions at the paranode in myelinated nerves cause axonal degeneration and neuronal cell death in the aged Caspr mutant mouse shambling2016
- Author(s)
  Takagishi, Y., Katanosaka, K., Mizoguchi, H., Murata, Y
- Journal Title
  
  Neurobiology of Aging
  
  Volume: 43 Pages: 34-46
- DOI
  10.1016/j.neurobiolaging.2016.03.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03011, KAKENHI-PROJECT-16H03303, KAKENHI-PROJECT-15K15204
[Journal Article] Insular neural system controls decision-making in healthy and methamphetamine-treated rats2015
- Author(s)
  Mizoguchi H, Katahira K, Inutsuka A, Fukumoto K, Nakamura A, Wang T, Nagai T, Sato J, Sawada M, Ohira H,Yamanaka A, Yamada K
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 112 (29) Issue: 29 Pages: 3930-3939
- DOI
  10.1073/pnas.1418014112
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26640041, KAKENHI-PUBLICLY-15H01428, KAKENHI-PUBLICLY-26118506, KAKENHI-PUBLICLY-26118507, KAKENHI-PUBLICLY-26120713, KAKENHI-PROJECT-24243068, KAKENHI-PROJECT-25460093, KAKENHI-PROJECT-25460094, KAKENHI-PROJECT-26860157, KAKENHI-PROJECT-25284003, KAKENHI-PROJECT-26293046, KAKENHI-PROJECT-26293053
[Journal Article] Fingolimod increases brain-derived neurotrophic factor levels and ameliorates amyloid beta-induced memory impairment2014
- Author(s)
  Fukumoto K, Mizoguchi H, Takeuchi H, Horiuchi H, Kawanokuchi J, Jin, SJ, Mizuno T, Suzumura A
- Journal Title
  
  Behavioural brain research
  
  Volume: 268 Pages: 88-93
- DOI
  10.1016/j.bbr.2014.03.046
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460094, KAKENHI-PUBLICLY-26120713
[Journal Article] Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice2013
- Author(s)
  D Ibi, I Nagai, A Nakajima, H Mizoguchi, T Kawase, D Tsuboi, S Kano, Y Sato, M Hayakawa, U. C. Lange, D. J. Adams, M. Azim Surani, T Satoh, A Sawa, K Kaibuchi, T Nabeshima and K Yamada
- Journal Title
  
  Glia
  
  Volume: 61 Issue: 5 Pages: 679-693
- DOI
  10.1002/glia.22461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J03454, KAKENHI-PROJECT-20227006, KAKENHI-PROJECT-22390046, KAKENHI-PROJECT-23591594, KAKENHI-PROJECT-23790290, KAKENHI-PROJECT-23791220, KAKENHI-PUBLICLY-24111518, KAKENHI-PROJECT-24657140
[Journal Article] Roles of matrix metalloproteinases and their targets in epileptogenesis and seizure2013
- Author(s)
  Mizoguchi H
- Journal Title
  
  Clinical Psychopharmacology and Neuroscience
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790082
[Journal Article] Nicotine ameliorates impairment of working memory in methamphetamine-treated rats2011
- Author(s)
  Mizoguchi H, et al.
- Journal Title
  
  Behav Brain Res.
  
  Volume: 220 Pages: 159-163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790068
[Journal Article] Matrix metalloproteinase-9 contributes to kindled seizure development in pentylenetetrazole-treated mice by converting pro-BDNF to mature BDNF in the hippocampus2011
- Author(s)
  H Mizoguchi, J Nakade, M Tachibana, D Ibi, E Someya, H Koike, H Kamei, T Nabeshima, S Itohara, K Takuma, M Sawada, J Sato, K Yamada
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 31 Issue: 36 Pages: 12963-12971
- DOI
  10.1523/jneurosci.3118-11.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J03454, KAKENHI-PROJECT-22390046, KAKENHI-PROJECT-23650190, KAKENHI-PROJECT-23659135, KAKENHI-PROJECT-23790082
[Journal Article] Chronic restraint stress impairs neurogenesis and hippocampus-dependent fear memory in mice : possible involvement of a brain-specific transcription factor Npas4.2011
- Author(s)
  Yun J, Koike H, Ibi D, Toth E, Mizoguchi H, Nitta A, Yoneyama M, Ogita K, Yoneda Y, Nabeshima T, Nagai T, Yamada K.
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 30 Pages: 5702-5712
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591173
[Journal Article] Matrix metalloproteinases contribute to neuronal dysfunction in animal models of drug dependence, Alzheimer's disease and epilepsy2011
- Author(s)
  Hiroyuki Mizoguchi, et al
- Journal Title
  
  Biochemistry Research International
  
  Volume: 2011 Pages: 681385-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390046
[Journal Article] Lowering barometric pressure aggravates depression-like behavior in rats.2011
- Author(s)
  Mizoguchi H, Fukaya K, Mori R, Itoh M, Funakubo M, Sato J.
- Journal Title
  
  Behav Brain Res. 218
  
  Pages: 190-193
- Data Source
  KAKENHI-PROJECT-21790068
[Journal Article] Chronic restraint stress impairs neurogenesis and hippocampus-dependent fear memory in mice: possible involvement of a brain-specific transcription factor Npas42011
- Author(s)
  Yun J, Koike H, Ibi D, Toth E, Mizoguchi H, Nitta A, Yoneyama M, Ogita K, Yoneda Y, Nabeshima T, Nagai T, Yamada K.
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: Vol. 30 Pages: 5702-5712
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591173
[Journal Article] Nicotine ameliorates impairment of working memory in methamphetamine-treated rats2011
- Author(s)
  Hiroyuki Mizoguchi, et al
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 221 Issue: 1 Pages: 159-163
- DOI
  10.1016/j.bbr.2011.01.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390046
[Journal Article] Alterations of emotional and cognitive behaviors in matrix metalloproteinase-2 and 9-deficient mice.2011
- Author(s)
  Mizoguchi H, et al.
- Journal Title
  
  The Open Behav Sci J.
  
  Volume: 4 Pages: 19-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790068
[Journal Article] Butrylcholinesterase inhibitors ameliorate cognitive dysfunction induced by amyloid-βpeptide in mice2011
- Author(s)
  Yoko Furukawa-Hibi, et al
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 225 Issue: 1 Pages: 222-229
- DOI
  10.1016/j.bbr.2011.07.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390046, KAKENHI-PROJECT-23659135
[Journal Article] Matrix metalloproteinases contribute to neuronal dysfunction in animal models of drug dependence, Alzheimer’s disease, and epilepsy.2011
- Author(s)
  Mizoguchi H, Yamada K and Nabeshima T
- Journal Title
  
  Biochem. Res. Int.
  
  Volume: 2011 Pages: 681385-681385
- DOI
  10.1155/2011/681385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659135, KAKENHI-PROJECT-23790082
[Journal Article] Nicotine ameliorates impairment of working memory in methamphetamine-treated rats.2011
- Author(s)
  Mizoguchi H, Ibi D, Takase F, Nagai T, Kamei H, Toth E, Sato J, Takuma K, Yamada K.
- Journal Title
  
  Behav Brain Res. 220
  
  Pages: 159-163
- Data Source
  KAKENHI-PROJECT-21790068
[Journal Article] Lowering barometric pressure aggravates depression-like behavior in rats.2011
- Author(s)
  Mizoguchi H, et al.
- Journal Title
  
  Behav Brain Res.
  
  Volume: 218 Pages: 190-193
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790068
[Journal Article] Yamada K Alterations of emotional and cognitive behaviors in matrix metalloproteinase-2 and -9-deficient mice.2010
- Author(s)
  Mizoguchi H, Ibi D, Takuma K, Toth E, Sato J, Itohara S, Nabeshima T
- Journal Title
  
  The Open Behav Sci J. 4
  
  Pages: 19-25
- Data Source
  KAKENHI-PROJECT-21790068
[Journal Article] Chronic restraint stress impairs neurogenesis and hippocampus-dependent fear memory in mice : a possible involvement of a brain specific transcription factor Npas4.2010
- Author(s)
  Yun J, Koike H, Ibi D, Toth E, Mizoguchi H, Nitta A, Yoneyama M, Ogita K, Yoneda Y, Nabeshima T, Nagai T, Yamada K
- Journal Title
  
  J.Neurochem 114
  
  Pages: 1840-1851
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Mice Deficient for Glucagon Gene-Derived Peptides Display Normogl ycemia and Hyperplasia of Islet {alpha}-Cells But Not of Intestinal L-Cells.2009
- Author(s)
  Hayashi Y, Yamamoto M, Mizoguchi H, Watanabe C, Ito R, Yamamoto S, Sun XY, Murata Y.
- Journal Title
  
  Molecular Endocrinology 23
  
  Pages: 1990-1999
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591173
[Journal Article] Matrix metalloprotease-9 inhibition improves amyloid β-mediated cognitive impairment and neurotoxicity in mice.2009
- Author(s)
  Mizoguchi H, Takuma K, Fukuzaki E, Ibi D, Someya E, Akazawa K, Alkam T, Tsunekawa H, Mouri A, Noda Y, Nabeshima T, and Yamada K.
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics.
  
  Volume: Vol. 331 Pages: 14-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591173
[Journal Article] Neonatal polyI:C treatment in mice results in schizophrenia-like behavioral and neurochemical abnormalities in adulthood.2009
- Author(s)
  Ibi D, Nagai T, Kitahara Y, Mizoguchi H, Koike H, Shiraki A, Takuma K, Kamei H, Noda N, Nitta A, Nabeshima T, Yoneda Y, Yamada K
- Journal Title
  
  Neurosci.Res. 64
  
  Pages: 297-305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Therapeutic potential of nicotine for methamphetamine-induced impairment of sensorimotor gating : involvement of pallidotegmental neurons2009
- Author(s)
  Mizoguchi H, et al.
- Journal Title
  
  Psychopharmacology 207, 2
  
  Pages: 235-243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Matrix metalloprotease-9 inhibition improves amyloid β-mediated cognitive impairment and neurotoxicity in mice2009
- Author(s)
  Mizoguchi H, et al.
- Journal Title
  
  J Phamacol Exp Ther. 331(1)
  
  Pages: 14-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article]2009
- Author(s)
  山田清文, 溝口博之
- Journal Title
  
  臨床精神薬理ハンドブック第2版(医学書院)
  
  Pages: 78-83
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Mice Deficient for Glucagon Gene-Derived Peptides Display Normoglycemia and Hyperplasia of Islet {alpha}-Cells But Not of Intestinal L-Cells.2009
- Author(s)
  Hayashi Y, Yamamoto M, Mizoguchi H, Watanabe C, Ito R, Yamamoto S, Sun XY, and Murata Y.
- Journal Title
  
  Molecular Endocrinology
  
  Volume: Vol. 23 Pages: 1990-1999
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591173
[Journal Article] Matrix metalloprotease-9 inhibition improves amyloid β-mediated cognitive impairment and neurotoxicity in mice.2009
- Author(s)
  Mizoguchi H, Takuma K, Fukuzaki E, Ibi D, Someya E, Akazawa K, Alkam T, Tsunekawa H, Mouri A, Noda Y, Nabeshima T, Yamada K.
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics. 331
  
  Pages: 14-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591173
[Journal Article] Matrix metalloprotease-9 inhibition improves amyloid β-mediated cognitive impairment and neurotoxicity in mice2009
- Author(s)
  Mizoguchi H, Takuma K, Fukuzaki E, Ibi D, Someya E, Akazawa K, Alkam T, Tsunekawa H, Mouri A, Noda Y, Nabeshima T, Yamada K
- Journal Title
  
  J.Pharmacol.Exp.Ther. 331
  
  Pages: 14-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Matrix metalloprotease-9 inhibition improves amyloid.-mediated cognitive impairment and neurotoxicity in mice.2009
- Author(s)
  Mizoguchi H, Takuma K, Fukuzaki E, Ibi D, Someya E, Akazawa K, Alkam T, Tsunekawa H, Mouri A, Noda Y, Nabeshima T, Yamada K
- Journal Title
  
  J.Pharmacol.Exp.Ther. 331
  
  Pages: 14-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Therapeutic potential of nicotine for methamphetamine-induced impairment of sensorimotor gating : involvement of pallidotegmental neurons.2009
- Author(s)
  Mizoguchi H, Arai S, Koike H, Ibi D, Kamei H, Nabeshima T, Kim HC, Takuma K, Yamada K
- Journal Title
  
  Psychopharmacology 207
  
  Pages: 235-243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Tissue plasminogen activator is not involved in methamphetamineinduced neurotoxicity.2008
- Author(s)
  Fukakusa A, Mizoguchi H, Koike H, Nabeshima T, Takuma K, Yamada K
- Journal Title
  
  Journal of Pharmacological Sciences 106(2)
  
  Pages: 321-324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790052
[Journal Article] Tissue plasminogen activator is not involved in methamphetamine-induced neurotoxicity.2008
- Author(s)
  Fukakusa A, Mizoguchi H, Koike H, Nabeshima T, Takuma K, Yamada K
- Journal Title
  
  J.Pharmacol.Sci. 106
  
  Pages: 321-324
- NAID
  10024318646
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Involvement of matrix metalloproteinase-2 and -9, and tissue inhibitor of matrix metalloproteinase-2 in methamphetamine-induced behavioral sensitization and reward in rodents.2008
- Author(s)
  Mizoguchi, et al.
- Journal Title
  
  J. Pharmacol. Sci. 106
  
  Pages: 9-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Social isolation rearing-induced impairment of the hippocampal neurogenesis is associated with deficits in spatial memory and emotion-related behaviors in juvenile mice2008
- Author(s)
  Ibi D, Takuma K, Koike H, Mizoguchi H, Tsuritani K, Kuwahara Y, Kamei H, Nagai T, Yoneda Y, Nabeshima T, Yamada K
- Journal Title
  
  J.Neurochem 105
  
  Pages: 921-932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Improvement by minocycline of methamphetamine-induced impairment of recognitionmemory in mite.2008
- Author(s)
  Mizoguchi H, et. al.
- Journal Title
  
  Psychopharmacology (Berl) 196
  
  Pages: 233-241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Role of tissue plasminogen activator in the sensitization of methamphetamine-induced dopamine release in the nucleus accumbens2008
- Author(s)
  Fukakusa A, Nagai T, Mizoguchi H, Otsuka N, Kimura H, Kamei H, Kim H-C, Nabeshima T, Takuma K, Yamada K
- Journal Title
  
  J.Neurochem 105
  
  Pages: 436-444
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Neuropsychotoxicity of abused drugs: involvement of matrix metalloproteinase-2 and -9 and tissue inhibitor of matrix metalloprote inase-2 in methamphetamine-induced behavioral sensitization and reward in rodents.2008
- Author(s)
  Mizoguchi H, Yamada K, Nabeshima T.
- Journal Title
  
  Journal of Pharmacological Sciences 106(1)
  
  Pages: 9-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790052
[Journal Article] Role of tissue plasminogen activator in the sensitization of methamphetamine-induced dopamine release in the nucleus accumbens.2008
- Author(s)
  Fukakusa A, Nagai T, Mizoguchi H, Otsuka N, Kimura H, Kamei H, Kim H-C, Nabeshima T, Takuma K, Yamada K
- Journal Title
  
  J.Neurochem. 105
  
  Pages: 436-444
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Social isolation rearing-induced impairment of the hippocampal neurogenesis is associated with deficits in spatial memory and emotion-related behaviors in juvenile mice.2008
- Author(s)
  Ibi D, Takuma K, Koike H, Mizoguchi H, Tsuritani K, Kuwahara Y, Kamei H, Nagai T, Yoneda Y, Nabeshima T, Yamada K
- Journal Title
  
  J.Neurochem. 105
  
  Pages: 921-932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Neuropsychotoxicity of Abused Drugs: Involvement of matrix metalloproteinase-2 and-9, and tissue inhibitor of matrix metalloproteinase-2 in methamphetamine-induced behavioralsensitization and reward in rodents.2008
- Author(s)
  Mizoguchi H, et. al.
- Journal Title
  
  J. Pharmacol. Sci. 106
  
  Pages: 9-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Improvement by minocycline of methamphetamine-induced impairment of recognition memory in mice.2008
- Author(s)
  Mizoguchi H, Takuma K, Fukakusa A, Ito Y, Nakatani A, Ibi D, Kim HC, Yamada K
- Journal Title
  
  Psychopharmacology(Berl) 196(2)
  
  Pages: 233-241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790052
[Journal Article] Improvement by minocycline of methamphetamine-induced impairment of recognition memory in mice.2008
- Author(s)
  Mizoguchi, et al.
- Journal Title
  
  Psychopharmacology (Berl) 196
  
  Pages: 233-241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Role of matrix metalloproteinase (MMP) and tissue inhibitor of MMP (TIMP) in methamphetamine-induced behavioral sensitization and reward: Implications for dopamine receptor downregulation and dopamine release2007
- Author(s)
  Mizoguchi H, Yamada K, Niwa M, Mouri A, Mizuno T, Noda Y, Nitta A, Itohara S, Banno Y, Nabeshima T.
- Journal Title
  
  Journal of Neurochemistry 102(5)
  
  Pages: 1548-1560
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790052
[Journal Article] Ginkgo biloba extract EGb761 attenuates hippocampal neuronal loss and cognitive dysfunction resulting from chronic restraint stress in ovariectomized rats.2007
- Author(s)
  Takuma K, Hoshina, Y, Arai S, Himeno Y, Matsuo, A, Funatsu Y, Kitahara Y, Ibi, D, Hayase M, Kamei H, Mizoguchi H, Nagai T, Koike K, Inoue M, Yamada K
- Journal Title
  
  Neuroscience 149
  
  Pages: 256-262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Activation of post-synaptic dopamine D1 receptors promotes the release of tissue plasminogen activator in the nucleus accumbens via PKA signaling.2007
- Author(s)
  Ito M, Nagai T, Mizoguchi H, Sato K, Hayase M, Otsuka N, Fukakusa A, Kumagai N, Kim H-C, Nabeshima T, Takuma K, Yamada K
- Journal Title
  
  J.Neurochem. 103
  
  Pages: 2589-2596
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Role of matrix metalloproteinase (MMP) and tissue inhibitor of MMP (TIMP) in methamphetamine-induced behavioral sensitization and reward : Implications for dopamine receptor downregulation and dopamine release2007
- Author(s)
  溝口博之
- Journal Title
  
  Journal of Neurochemistry (印刷中)
- Data Source
  KAKENHI-PROJECT-18790052
[Journal Article] Activation of post-synaptic dopamine D_1 receptors promotes the release of tissue plasminogen activator in the nucleus accumbens via PKA signaling2007
- Author(s)
  Ito M, Nagai T, Mizoguchi H, Sato K, Hayase M, Otsuka N, Fukakusa A, Kumagai N, Kim H-C, Nabeshima T, Takuma K, Yamada K
- Journal Title
  
  J.Neurochem 103
  
  Pages: 2589-2596
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Reduction of methamphetamine-induced sensitization and reward in matrix metalloproteinase-2 and -9 deficient mice2007
- Author(s)
  溝口博之
- Journal Title
  
  Journal of Neurochemistry 100(6)
  
  Pages: 1579-1588
- Data Source
  KAKENHI-PROJECT-18790052
[Journal Article] oles of matrix metalloproteinases and their targets in epileptogenesis and seizure
- Author(s)
  Mizoguchi H, Yamada K
- Journal Title
  
  Clin Psychopharmacol Neurosci
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-23790082
[Presentation] Orexin neurons mediates motivation under reward-based motivative behavior2024
- Author(s)
  Yutao Dong, Hiroyuki Mizoguchi, Akihiro Yamanaka, Kiyofumi Yamada
- Organizer
  第144回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-22K19749
[Presentation] Reln-del Mice Exhibit Defects in Neural Circuitry and Social Communication2023
- Author(s)
  Youyun Zhu, Yumi Tsuneura, Hiroyuki Mizoguchi, Masahito Sawahata, Daisuke Mori, Takao Kohno, Mitsuharu Hattori, Toshitaka Nabeshima, Norio Ozaki, Kiyofumi Yamada
- Organizer
  第143回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-22K19749
[Presentation] Abnormal behavior and glial responses in an animal model of tau pathology2023
- Author(s)
  Yue Liu, Hiroyuki Mizoguchi1,Akira Sobue, Naruhiko Shara, Koji Yamanaka, Kiyofumi Yamada
- Organizer
  第97回日本薬理学会年会・第44回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-22K19749
[Presentation] Rho-kinase 2選択的阻害剤は日本人統合失調症患者で見つかったArhgap10 遺伝子バリアントを有するマウスの内側前頭前皮質のスパイン密度低下を改善する2023
- Author(s)
  田中里奈子、朱　文俊、森　大輔、毛利彰宏、永井　拓、鍋島俊隆、貝淵弘三、橘　大輝、小林洋平、尾崎紀夫、溝口博之、山田清文
- Organizer
  第97回日本薬理学会年会・第44回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-22K19749
[Presentation] Selective rho-associated protein kinase inhibitor has the potential to be a novel therapeutic target for schizophrenia2023
- Author(s)
  Wenjun Zhu, Rinako Tanaka, Jingzhu Liao, Daisuke Mori, Akihiro Mouri, Hiroyuki Mizoguchi, Taku Nagai, Toshitaka Nabeshima, Kozo Kaibuchi, Yohei Kobayashi, Norio Ozaki, Kiyofumi Yamada
- Organizer
  第53回日本神経精神薬理学会年会
- Data Source
  KAKENHI-PROJECT-22K19749
[Presentation] Comprehensive phosphoproteomic analysis in reelin mutant mice identified an important role of twinfilin 1 in spine development and actin dynamics.2023
- Author(s)
  Geyao Dong, Norimichi Itoh, Takaaki Matsui, Ayato　Sato, Tetsuo Matsuzaki, Hiroyuki Mizoguchi, Daisuke Mori, Taku Nagai, Toshitaka Nabeshima, Norio Ozaki, Kiyofumi Yamada
- Organizer
  The 34th CINP World Congress of Neuropsychopharmacology (CINP2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27360
[Presentation] Phosphoproteomic Insights into Methamphetamine-Induced Cognitive Dysfunction2023
- Author(s)
  Wenjun Zhu, Jingzhu Liao, Geyao Dong, Rinako Tanaka, Tetsuo Matsuzaki, Hiroyuki Mizoguchi, Kozo Kaibuchi, Norio Ozaki, Toshitaka Nabeshima, Taku Nagai and Kiyofumi Yamada
- Organizer
  2023年度アルコール・薬物依存関連学会合同学術総会
- Data Source
  KAKENHI-PROJECT-22K19749
[Presentation] Twinfilin 1 Phosphorylation is Crucial For Reelin Signaling In The Regulation Of Spine Morphology And Cognitive Function2023
- Author(s)
  Kiyofumi Yamada, Geyao Dong, Norimichi Itoh, Takaaki Matsui, Ayato Sato,Tetsuo Matsuzaki , Hiroyuki Mizoguchi, Daisuke Mori, Taku Nagai, Norio Ozaki, Toshitaka Nabeshima
- Organizer
  The 34th CINP World Congress of Neuropsychopharmacology (CINP2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27360
[Presentation] Neuronal morphological impairments in the model mice carrying the same deletion of RELN gene that was identified in a Japanese schizophrenia patient.2022
- Author(s)
  朱　悠韻、常浦　祐未、溝口　博之、澤幡　雅仁、森　大輔、河野　孝夫、服部　光治、鍋島　俊隆、尾崎　紀夫、山田　清文
- Organizer
  第142回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-20H03428
[Presentation] Arhgap10遺伝子変異マウスの神経活動の解析にむけたin vivoカルシウムイメージング法の確立2022
- Author(s)
  田中里奈子、羽田和弘、溝口博之、澤幡雅仁、永井拓、森大輔、鍋島俊隆、貝淵弘三、尾崎紀夫、山田清文
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03428
[Presentation] 意欲、衝動とオレキシン神経2022
- Author(s)
  溝口博之、山中章弘、山田清文
- Organizer
  BPCNPNPPP 4学会合同年会
- Data Source
  KAKENHI-PROJECT-22K19749
[Presentation] Changes in expression of interferon-induced transmembrane protein-3 (IFITM3) in the brain of animal model mice of Alzheimer's diseas.2022
- Author(s)
  Yue Liu, Hiroyuki Mizoguchi, Akira Sobue, Koji Yamanaka, Kiyofumi Yamada.
- Organizer
  第96回日本薬理学会年会・第43回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-22K19749
[Presentation] Functional roles of orexin neurons in reward-based motivative behavior in rats.2022
- Author(s)
  Hiroyuki Mizoguchi, Yutao Dong, Akihiro Yamanaka, Kiyofumi Yamada.
- Organizer
  Neuro2022
- Data Source
  KAKENHI-PROJECT-22K19749
[Presentation] 依存症の発症機序と精神薬理2022
- Author(s)
  溝口博之
- Organizer
  BPCNPNPPP 4学会合同年会
- Data Source
  KAKENHI-PROJECT-22K19749
[Presentation] Phosphorylated twinfilin1 plays a major role in dendritic spine development, but not brain layer formation2022
- Author(s)
  Geyao Dong, Norimichi Itoh, Tetsuo Matsuzaki, Hiroyuki Mizoguchi, Daisuke Mori, Taku Nagai,Toshitaka Nabeshima, Norio Ozaki, Kiyofumi Yamada
- Organizer
  BPCNPNPPP4学会合同年会
- Data Source
  KAKENHI-PROJECT-20H03428
[Presentation] Phosphorylation of twinfilin-1 involved in the reelin signaling plays a crucial role in spine development2022
- Author(s)
  Geyao Dong, Norimichi Itoh, Hiroyuki Mizoguchi , Tetsuo Matsuzaki, Daisuke Mori, Taku Nagai, Toshitaka Nabeshima, Norio Ozaki, Kiyofumi Yamada
- Organizer
  JPW2022
- Data Source
  KAKENHI-PROJECT-20H03428
[Presentation] Dynamic changes in orexin activities in reward-based motivative behavior.2022
- Author(s)
  Yutao Dong、溝口博之、山中章弘、山田清文
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K21811
[Presentation] Dynamic changes in orexin activities in reward-based motivative behavior.2022
- Author(s)
  Yutao Dong、溝口博之、山中章弘、山田清文
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19H03532
[Presentation] Spine morphological changes in Reln-del mice（リーリンモデルマウスにスパインの形態変化について研究）2022
- Author(s)
  Youyun Zhu、Yumi Tsuneura、Hiroyuki Mizoguchi、Masahito Sawahata、Daisuke Mori、Takao Kohno、Mitsuharu Hattori、Toshitaka Nabeshima、Norio Ozaki、Kiyofumi Yamada.
- Organizer
  NEURO2022
- Data Source
  KAKENHI-PROJECT-20H03428
[Presentation] Activities of orexin neurons in motivative behavior.2021
- Author(s)
  Yutao Dong、溝口博之、山中章弘、山田清文
- Organizer
  第139回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-19H03532
[Presentation] 依存症がもたらす意思決定異常と脳内報酬系2021
- Author(s)
  溝口博之
- Organizer
  2021年度アルコール・薬物依存関連学会合同学術総会
- Data Source
  KAKENHI-PROJECT-19H03532
[Presentation] Activities of orexin neurons in motivative behavior2021
- Author(s)
  Yutao Dong、溝口博之、山中章弘、山田清文
- Organizer
  第139回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-19K21811
[Presentation] 報酬獲得行動に関わる脳内ネットワークの追究2021
- Author(s)
  溝口博之
- Organizer
  2021年度アルコール・薬物依存関連学会合同学術総会
- Data Source
  KAKENHI-PROJECT-19K21811
[Presentation] 報酬獲得行動に関わる脳内ネットワークの追究2021
- Author(s)
  溝口博之
- Organizer
  2021年度アルコール・薬物依存関連学会合同学術総会
- Data Source
  KAKENHI-PROJECT-19H03532
[Presentation] MK-801処置マウスの統合失調症様行動及び側坐核における神経伝達物質遊離に対するRhoキナーゼ阻害剤ファスジルの効果2021
- Author(s)
  田中里奈子、澤幡雅仁、高瀨冴子、Liu Yue、羽田和弘、溝口博之、永井拓、鍋島俊隆、尾崎紀夫、山田清文
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03428
[Presentation] 依存症がもたらす意思決定異常と脳内報酬系2021
- Author(s)
  溝口博之
- Organizer
  2021年度アルコール・薬物依存関連学会合同学術総会
- Data Source
  KAKENHI-PROJECT-19K21811
[Presentation] 認知症早期発見と創薬への行動薬理学研究者の挑戦.2020
- Author(s)
  溝口博之、山中宏二.
- Organizer
  第30回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-19H03532
[Presentation] タッチスクリーン式学習試験法はアルツハイマー病モデル動物の早期の認知機能障害を検出できる.2020
- Author(s)
  溝口博之、小峯　起、Md. Ali Bin Saifullah1、祖父江　顕、遠藤史人、山中宏二
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PUBLICLY-19H05017
[Presentation] 動機づけ行動におけるオレキシン神経の役割2020
- Author(s)
  溝口博之、犬束歩、片平健太郎、山田清文、山中章弘.
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PUBLICLY-19H05017
[Presentation] 依存症の理解に向けた意思決定の神経回路の解明.2020
- Author(s)
  溝口博之、山田清文、山中章弘.
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19H03532
[Presentation] 動機づけ行動におけるオレキシン神経の役割2020
- Author(s)
  溝口博之、犬束歩、片平健太郎、山田清文、山中章弘.
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19H03532
[Presentation] 動機づけ行動におけるオレキシン神経の役割2020
- Author(s)
  溝口博之、犬束歩、片平健太郎、山田清文、山中章弘.
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K21811
[Presentation] 意思決定異常に対する創薬標的：バレニクリンの有効性.2020
- Author(s)
  溝口博之、山田清文
- Organizer
  第137回日本薬理学会近畿部会
- Data Source
  KAKENHI-PUBLICLY-19H05017
[Presentation] 認知症早期発見と創薬への行動薬理学研究者の挑戦.2020
- Author(s)
  溝口博之、山中宏二.
- Organizer
  第30回日本医療薬学会年会
- Data Source
  KAKENHI-PUBLICLY-19H05017
[Presentation] 依存症の理解に向けた意思決定の神経回路の解明.2020
- Author(s)
  溝口博之、山田清文、山中章弘.
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PUBLICLY-19H05017
[Presentation] 意思決定異常に対する創薬標的：バレニクリンの有効性.2020
- Author(s)
  溝口博之、山田清文
- Organizer
  第137回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-19H03532
[Presentation] 依存症の理解に向けた意思決定の神経回路の解明.2020
- Author(s)
  溝口博之、山田清文、山中章弘.
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19K21811
[Presentation] 意思決定異常に対する創薬標的：バレニクリンの有効性.2020
- Author(s)
  溝口博之、山田清文.
- Organizer
  第137回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-19K21811
[Presentation] 認知症早期発見と創薬への行動薬理学研究者の挑戦.2020
- Author(s)
  溝口博之、山中宏二.
- Organizer
  第30回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-19K21811
[Presentation] タッチスクリーン式学習試験法はアルツハイマー病モデル動物の早期の認知機能障害を検出できる.2020
- Author(s)
  溝口博之、小峯　起、Md. Ali Bin Saifullah1、祖父江　顕、遠藤史人、山中宏二.
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K21811
[Presentation] タッチスクリーン式学習試験法はアルツハイマー病モデル動物の早期の認知機能障害を検出できる.2020
- Author(s)
  溝口博之、小峯　起、Md. Ali Bin Saifullah1、祖父江　顕、遠藤史人、山中宏二.
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19H03532
[Presentation] Roles of orexin neurons in motivated behaviors in rats.2019
- Author(s)
  Mizoguchi H, Inutsuka A, Katahira K, Yamada K, Yamanaka A.
- Organizer
  6th Congress of Asian College of Neuropsycopharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H05017
[Presentation] 依存症における意思決定異常と島皮質GABA神経2019
- Author(s)
  溝口博之、山田清文
- Organizer
  第49回日本神経精神薬理学会
- Data Source
  KAKENHI-PUBLICLY-19H05017
[Presentation] 依存症における意思決定の神経回路：島皮質と線条体.2019
- Author(s)
  溝口博之、山田清文
- Organizer
  第42回日本神経科学大会第62回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-19K21811
[Presentation] Touchscreen-based tests detect cognitive impairment at an early stage in APP knock-in mice model.2019
- Author(s)
  Saifullah Md. Ali Bin , Komine O, Sobue A, Yamanaka K, Mizoguchi H.
- Organizer
  6th Congress of Asian College of Neuropsycopharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H05017
[Presentation] 依存症における意思決定の神経回路：島皮質と線条体.2019
- Author(s)
  溝口博之、山田清文
- Organizer
  第42回日本神経科学大会第62回日本神経化学会大会,
- Data Source
  KAKENHI-PROJECT-19H03532
[Presentation] Roots of decision-making in addiction: the insular cortex, nucleus accumbens, striatum.2019
- Author(s)
  Mizoguchi H
- Organizer
  7th Meeting of the International Drug Abuse Research Society (IDARS).
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21811
[Presentation] Touchscreen-based tests detect cognitive impairment at an early stage in APP knock-in mice model.2019
- Author(s)
  Saifullah Md. Ali Bin , Komine O, Sobue A, Yamanaka K, Mizoguchi H.
- Organizer
  6th Congress of Asian College of Neuropsycopharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21811
[Presentation] 食欲、報酬に対する動機づけにおけるオレキシン神経の役割2019
- Author(s)
  溝口博之
- Organizer
  第4 回食欲・食嗜好の分子・神経基盤研究会
- Data Source
  KAKENHI-PROJECT-19K21811
[Presentation] Optimization of operant test for testing risky decision-making in mice.2019
- Author(s)
  Mizoguchi H、Wang T、Saifullah Md. Ali Bin 、Fukumoto K、 Mizoguchi H、Yamada K.
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PUBLICLY-17H06053
[Presentation] Optimization of operant test for testing risky decision-making in mice.2019
- Author(s)
  Mizoguchi H、Wang T、Saifullah Md. Ali Bin 、Fukumoto K、 Mizoguchi H、Yamada K.
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-16H03303
[Presentation] 依存症における意思決定異常と島皮質GABA神経2019
- Author(s)
  溝口博之、山田清文
- Organizer
  第49回日本神経精神薬理学会
- Data Source
  KAKENHI-PROJECT-19K21811
[Presentation] Roles of orexin neurons in motivated behaviors in rats.2019
- Author(s)
  Mizoguchi H, Inutsuka A, Katahira K, Yamada K, Yamanaka A.
- Organizer
  6th Congress of Asian College of Neuropsycopharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03532
[Presentation] 報酬に対する動機づけにおけるオレキシン神経の役割.2019
- Author(s)
  溝口博之
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2019
- Data Source
  KAKENHI-PROJECT-19K21811
[Presentation] 依存症における意思決定の神経回路：島皮質と線条体.2019
- Author(s)
  溝口博之、山田清文.
- Organizer
  第42回日本神経科学大会第62回日本神経化学会大会
- Data Source
  KAKENHI-PUBLICLY-19H05017
[Presentation] 依存症における意思決定異常と島皮質GABA神経2019
- Author(s)
  溝口博之、山田清文
- Organizer
  第49回日本神経精神薬理学会
- Data Source
  KAKENHI-PROJECT-19H03532
[Presentation] 報酬に対する動機づけにおけるオレキシン神経の役割2019
- Author(s)
  溝口博之
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会
- Data Source
  KAKENHI-PUBLICLY-19H05017
[Presentation] Touchscreen-based tests detect cognitive impairment at an early stage in APP knock-in mice model.2019
- Author(s)
  Saifullah Md. Ali Bin , Komine O, Sobue A, Yamanaka K, Mizoguchi H.
- Organizer
  6th Congress of Asian College of Neuropsychopharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03532
[Presentation] Behavioral characterization of APP knock-in mice model in touchscreen-based tests aiming early detection of Alzheimer’s disease.2019
- Author(s)
  Saifullah Md. Ali Bin、Komine O、Ｓｏｂｕｅ A、Yamanaka K、Mizoguchi H.
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-16H03303
[Presentation] Roles of orexin neurons in motivated behaviors in rats.2019
- Author(s)
  Mizoguchi H, Inutsuka A, Katahira K, Yamada K, Yamanaka A.
- Organizer
  6th Congress of Asian College of Neuropsycopharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21811
[Presentation] Roots of decision-making in addiction: the insular cortex, nucleus accumbens, striatum.2019
- Author(s)
  Mizoguchi H.
- Organizer
  7th Meeting of the International Drug Abuse Research Society (IDARS).
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H05017
[Presentation] 報酬に対する動機づけにおけるオレキシン神経の役割.2019
- Author(s)
  溝口博之.
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会
- Data Source
  KAKENHI-PROJECT-19H03532
[Presentation] 食欲、報酬に対する動機づけにおけるオレキシン神経の役割.2019
- Author(s)
  溝口博之.
- Organizer
  第4 回食欲・食嗜好の分子・神経基盤研究会
- Data Source
  KAKENHI-PUBLICLY-19H05017
[Presentation] Roots of decision-making in addiction: the insular cortex, nucleus accumbens, striatum.2019
- Author(s)
  Mizoguchi H.
- Organizer
  7th Meeting of the International Drug Abuse Research Society (IDARS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03532
[Presentation] 食欲、報酬に対する動機づけにおけるオレキシン神経の役割2019
- Author(s)
  溝口博之
- Organizer
  第4 回食欲・食嗜好の分子・神経基盤研究会
- Data Source
  KAKENHI-PROJECT-19H03532
[Presentation] Behavioral characterization of APP knock-in mice model in touchscreen-based tests aiming early detection of Alzheimer’s disease.2019
- Author(s)
  Saifullah Md. Ali Bin、Komine　Ｏ、Ｓｏｂｕｅ　Ａ、Yamanaka K、Mizoguchi H.
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PUBLICLY-17H06053
[Presentation] 依存性薬物がもたらす認知・行動選択異常の解明に向けた基礎研究.2018
- Author(s)
  溝口博之.
- Organizer
  第28回日本臨床精神神経薬理学会・第48回日本神経精神薬理学会合同年会
- Invited
- Data Source
  KAKENHI-PROJECT-16H03303
[Presentation] 依存症抑止に向けた認知・意思決定異常の解明.2018
- Author(s)
  溝口博之、山田清文.
- Organizer
  第53回アルコール・アディクション医学会学術総会.
- Data Source
  KAKENHI-PROJECT-16H03303
[Presentation] タッチスクリーン式弁別課題を用いた認知機能解析システムの確立2018
- Author(s)
  Md.Ali Bin Saifullah, 山中宏二，溝口博之
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K13505
[Presentation] Roots of risky decisions in drug dependence.2018
- Author(s)
  Mizoguchi H、Yamada K.
- Organizer
  10th International Symposium on Cell/Tissue Injury and Cytoprotection/Organoprotection
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03303
[Presentation] 依存性薬物がもたらす認知・行動選択異常の解明に向けた基礎研究.2018
- Author(s)
  溝口博之.
- Organizer
  第28回日本臨床精神神経薬理学会・第48回日本神経精神薬理学会合同年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H06053
[Presentation] 認知症との共生社会を支える基礎研究.2018
- Author(s)
  溝口博之.
- Organizer
  日本心理学会第82回大会
- Data Source
  KAKENHI-PUBLICLY-17H06053
[Presentation] ラットの動機づけ行動におけるオレキシン神経の役割.2018
- Author(s)
  溝口博之、犬束歩、片平健太郎、山田清文、山中章弘.
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PUBLICLY-17H06053
[Presentation] タッチスクリーン式弁別課題を用いた認知機能解析システムの確立2018
- Author(s)
  Md.Ali Bin Saifullah, 山中宏二，溝口博之
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H03303
[Presentation] ラットの動機づけ行動におけるオレキシン神経の役割.2018
- Author(s)
  溝口博之、犬束歩、片平健太郎、山田清文、山中章弘.
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16H03303
[Presentation] タッチスクリーン式弁別課題を用いた認知機能解析システムの確立2018
- Author(s)
  Md.Ali Bin Saifullah, 山中宏二，溝口博之
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PUBLICLY-17H06053
[Presentation] 食欲、報酬に対する動機づけ、意思決定におけるオレキシンの役割.2018
- Author(s)
  溝口博之.
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H03303
[Presentation] An Operant task for testing risky decision-making in mice.2018
- Author(s)
  Wang T、Fukumoto K、 Mizoguchi H、Yamada K.
- Organizer
  19th World Congress of International-Society-for-Biomedical-Research-on-Alcoholism (ISBRA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03303
[Presentation] 認知症との共生社会を支える基礎研究.2018
- Author(s)
  溝口博之.
- Organizer
  日本心理学会第82回大会
- Data Source
  KAKENHI-PROJECT-16H03303
[Presentation] Ventral pallidum neurons control aversive learning.2018
- Author(s)
  Macpherson T、 Mizoguchi H、Yamanaka A、Hikida T.
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PUBLICLY-17H06053
[Presentation] 依存症抑止に向けた認知・意思決定異常の解明.2018
- Author(s)
  溝口博之、山田清文.
- Organizer
  第53回アルコール・アディクション医学会学術総会.
- Data Source
  KAKENHI-PUBLICLY-17H06053
[Presentation] Ventral pallidum neurons control aversive learning.2018
- Author(s)
  Macpherson T、Mizoguchi H、Yamanaka A、Hikida T.
- Organizer
  Society for Neuroscience 2018 Annual Meeting
- Data Source
  KAKENHI-PUBLICLY-17H06053
[Presentation] Monomeric and dimeric RFP-dependent Cre and its application to detect glucocorticoid receptor activation.2018
- Author(s)
  Inutsuka A、Mizoguchi H、Kaneko R、Nomura R、Takanami K、Sakamoto H、Onaka T.
- Organizer
  Society for Neuroscience 2018 Annual Meeting
- Data Source
  KAKENHI-PUBLICLY-17H06053
[Presentation] Roots of risky decisions in addiction.2018
- Author(s)
  Mizoguchi H.
- Organizer
  The 4th IMCR Symposium on Endocrine and Metabolism
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H06053
[Presentation] Roots of risky decisions in addiction.2018
- Author(s)
  Mizoguchi H.
- Organizer
  The 4th IMCR Symposium on Endocrine and Metabolism
- Invited
- Data Source
  KAKENHI-PROJECT-16H03303
[Presentation] 基礎研究から探る覚せい剤依存の脳内機序.2018
- Author(s)
  溝口博之.
- Organizer
  第53回アルコール・アディクション医学会学術総会.
- Invited
- Data Source
  KAKENHI-PROJECT-16H03303
[Presentation] Roles of orexin neurons in motivated behaviors in rats.2018
- Author(s)
  Mizoguchi H、Inutsuka A、Katahira K、Yamada K、Yamanaka A.
- Organizer
  The 7th Annual IIIS Symposium ~Solving the mystery of sleep~
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H06053
[Presentation] 基礎研究から探る覚せい剤依存の脳内機序.2018
- Author(s)
  溝口博之.
- Organizer
  第53回アルコール・アディクション医学会学術総会.
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H06053
[Presentation] Monomeric and dimeric RFP-dependent Cre and its application to detect glucocorticoid receptor activation.2018
- Author(s)
  Inutsuka A、Mizoguchi H、Kaneko R、Nomura R、Takanami K、Sakamoto H、Onaka T.
- Organizer
  Society for Neuroscience 2018 Annual Meeting
- Data Source
  KAKENHI-PROJECT-16H03303
[Presentation] Ventral pallidum neurons control aversive learning.2018
- Author(s)
  Macpherson T、 Mizoguchi H、Yamanaka A、Hikida T.
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16H03303
[Presentation] 食欲、報酬に対する動機づけ、意思決定におけるオレキシンの役割.2018
- Author(s)
  溝口博之.
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-17H06053
[Presentation] An Operant task for testing risky decision-making in mice.2018
- Author(s)
  Wang T、Fukumoto K、 Mizoguchi H、Yamada K.
- Organizer
  19th World Congress of International-Society-for-Biomedical-Research-on-Alcoholism (ISBRA)
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H06053
[Presentation] Roles of orexin neurons in motivated behaviors in rats.2018
- Author(s)
  Mizoguchi H、Inutsuka A、Katahira K、Yamada K、Yamanaka A.
- Organizer
  The 7th Annual IIIS Symposium ~Solving the mystery of sleep~
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03303
[Presentation] Roots of risky decisions in drug dependence.2018
- Author(s)
  Mizoguchi H、Yamada K.
- Organizer
  10th International Symposium on Cell/Tissue Injury and Cytoprotection/Organoprotection
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H06053
[Presentation] Ventral pallidum neurons control aversive learning.2018
- Author(s)
  Macpherson T、Mizoguchi H、Yamanaka A、Hikida T.
- Organizer
  Society for Neuroscience 2018 Annual Meeting
- Data Source
  KAKENHI-PROJECT-16H03303
[Presentation] 島皮質GABA神経の機能操作は意思決定に影響する2017
- Author(s)
  溝口博之，犬束　歩，片平健太郎，山田清文
- Organizer
  次世代を担う創薬・医療管理シンポジウム 2017
- Data Source
  KAKENHI-PROJECT-16K13505
[Presentation] 島皮質GABA神経の機能操作は意思決定に影響する2017
- Author(s)
  溝口博之，犬束　歩，片平健太郎，山田清文
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2017
- Data Source
  KAKENHI-PROJECT-16H03303
[Presentation] リスク下の意思決定における島皮質GABA神経の役割2017
- Author(s)
  溝口博之，犬束　歩，片平健太郎，山田清文
- Organizer
  平成２９年度アルコール・薬物依存関連学会学術総会
- Data Source
  KAKENHI-PUBLICLY-17H06053
[Presentation] タッチスクリーン式弁別課題を用いた認知機能解析システムの確立2017
- Author(s)
  Md.Ali-Bin-Saifullah，溝口博之
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2017
- Data Source
  KAKENHI-PUBLICLY-17H06053
[Presentation] リスク下の意思決定における島皮質GABA神経の役割2017
- Author(s)
  溝口博之，犬束　歩，片平健太郎，山田清文
- Organizer
  平成２９年度アルコール・薬物依存関連学会合同学術総会
- Data Source
  KAKENHI-PROJECT-16K13505
[Presentation] 依存性薬物がもたらす認知・意思決定異常2017
- Author(s)
  溝口博之，山田清文
- Organizer
  第40回日本神経科学大会
- Invited
- Data Source
  KAKENHI-PROJECT-16H03303
[Presentation] 依存性薬物がもたらす認知・意思決定異常2017
- Author(s)
  溝口博之，山田清文
- Organizer
  第40回日本神経科学大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H06053
[Presentation] リスク下の意思決定における島皮質GABA神経の役割2017
- Author(s)
  溝口博之，犬束　歩，片平健太郎，山田清文
- Organizer
  平成２９年度アルコール・薬物依存関連学会合同学術総会
- Data Source
  KAKENHI-PROJECT-16H03303
[Presentation] タッチスクリーン式弁別課題を用いた認知機能解析システムの確立2017
- Author(s)
  Md.Ali-Bin-Saifullah，溝口博之
- Organizer
  次世代を担う創薬・医療管理シンポジウム 2017
- Data Source
  KAKENHI-PROJECT-16K13505
[Presentation] 島皮質GABA神経の機能操作は意思決定に影響する2017
- Author(s)
  溝口博之，犬束　歩，片平健太郎，山田清文
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2017
- Data Source
  KAKENHI-PUBLICLY-17H06053
[Presentation] 依存性薬物がもたらす認知・意思決定異常2017
- Author(s)
  溝口博之，山田清文
- Organizer
  第40回日本神経科学大会
- Invited
- Data Source
  KAKENHI-PROJECT-16K13505
[Presentation] タッチスクリーン式弁別課題を用いた認知機能解析システムの確立2017
- Author(s)
  Md.Ali-Bin-Saifullah，溝口博之
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2017
- Data Source
  KAKENHI-PROJECT-16H03303
[Presentation] 島皮質GABA神経は薬物依存ラットの意思決定に関与する2016
- Author(s)
  溝口博之、山田清文
- Organizer
  第39回日本神経科学会
- Place of Presentation
  パシフィコ横浜（横浜市西区）
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-26293053
[Presentation] 薬物依存症における意思決定異常2016
- Author(s)
  溝口博之、山田清文
- Organizer
  第46日本神経精神薬理学会年会
- Place of Presentation
  ソウル
- Year and Date
  2016-07-02
- Data Source
  KAKENHI-PROJECT-16K13505
[Presentation] 薬物依存における意思決定と島皮質機能障害2016
- Author(s)
  溝口博之
- Organizer
  第34回日本生理心理学会大会
- Place of Presentation
  名古屋
- Year and Date
  2016-05-14
- Data Source
  KAKENHI-PROJECT-16H03303
[Presentation] 意思決定障害と創薬標的としてのニコチン受容体2016
- Author(s)
  溝口博之、山田清文
- Organizer
  第18回応用薬理シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2016-08-05
- Data Source
  KAKENHI-PROJECT-16H03303
[Presentation] 島皮質GABA神経は薬物依存ラットの意思決定に関与する2016
- Author(s)
  溝口博之、山田清文
- Organizer
  第39回日本神経科学会
- Place of Presentation
  横浜
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-16K13505
[Presentation] 薬物依存における意思決定と島皮質機能障害2016
- Author(s)
  溝口博之
- Organizer
  第34回日本生理心理学会大会
- Place of Presentation
  名古屋
- Year and Date
  2016-05-14
- Data Source
  KAKENHI-PROJECT-16K13505
[Presentation] 薬物依存症における意思決定異常2016
- Author(s)
  溝口博之、山田清文
- Organizer
  第46回日本神経精神薬理学会
- Place of Presentation
  ソウル
- Year and Date
  2016-07-02
- Data Source
  KAKENHI-PROJECT-16H03303
[Presentation] 意思決定障害と創薬標的としてのニコチン受容体2016
- Author(s)
  溝口博之、山田清文
- Organizer
  第18回応用薬理シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2016-08-05
- Data Source
  KAKENHI-PROJECT-16K13505
[Presentation] 薬物依存症における意思決定異常2016
- Author(s)
  溝口博之、山田清文.
- Organizer
  第46回日本神経精神薬理学会
- Place of Presentation
  ソウル（韓国）
- Year and Date
  2016-07-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293053
[Presentation] 意思決定障害と創薬標的としてのニコチン受容体2016
- Author(s)
  溝口博之、山田清文
- Organizer
  第18回応用薬理シンポジウム
- Place of Presentation
  名古屋大学（愛知県名古屋市）
- Year and Date
  2016-08-05
- Data Source
  KAKENHI-PROJECT-26293053
[Presentation] 島皮質GABA神経は薬物依存ラットの意思決定に関与する2016
- Author(s)
  溝口博之、山田清文
- Organizer
  第39回日本神経科学会
- Place of Presentation
  横浜
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-16H03303
[Presentation] Nicotinic acetylcholine receptor as a target of harm reduction and treatment in addiction.2016
- Author(s)
  Mizoguchi H, Yamada K.
- Organizer
  第５１回日本アルコール・アディクション医学会学術総会
- Place of Presentation
  東京
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-16K13505
[Presentation] Nicotinic acetylcholine receptor as a target of harm reduction and treatment in addiction.2016
- Author(s)
  Mizoguchi H, Yamada K
- Organizer
  第５１回日本アルコール・アディクション医学会学術総会
- Place of Presentation
  東京
- Year and Date
  2016-10-07
- Invited
- Data Source
  KAKENHI-PROJECT-16H03303
[Presentation] Nicotinic acetylcholine receptor as a target of harm reduction and treatment in addiction.2016
- Author(s)
  溝口博之、山田清文
- Organizer
  第５１回日本アルコール・アディクション医学会学術総会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-26293053
[Presentation] Nicotine receptor as a potential target for treatment of pathological decision-making in addiction2015
- Author(s)
  Hiroyuki Mizoguchi, Kiyofumi Yamada.
- Organizer
  WPAIC 2015, 4th Asian Congress of Schizophrenia Research, 4th Congress of Asian College of Neuropsychopharmacology
- Place of Presentation
  Taipei、Taiwan
- Year and Date
  2015-11-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293053
[Presentation] The insular GABAergic system controls decision-making in healthy and drug-dependent animals2015
- Author(s)
  Hiroyuki Mizoguchi, Kiyofumi Yamada
- Organizer
  IBNS 24th Annual Meeting
- Place of Presentation
  Victoria, Canada
- Year and Date
  2015-06-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293053
[Presentation] Effect of nicotine on altered decision-making in methamphetamine-treated rat2015
- Author(s)
  Mizoguchi H, Wang T, Yamada K.
- Organizer
  International Symposium on Prediction and Decision Making 2015
- Place of Presentation
  東京
- Year and Date
  2015-10-31
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26120713
[Presentation] The insular GABAergic system controls decision-making in healthy and drug-dependent animals.2015
- Author(s)
  Mizoguchi H, Yamada K.
- Organizer
  IBNS 24th Annual Meeting
- Place of Presentation
  Victoria
- Year and Date
  2015-06-02
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26120713
[Presentation] Effect of nicotine on altered decision-making in methamphetamine-treated rat2015
- Author(s)
  Mizoguchi H, Wang T, Yamada K.
- Organizer
  International Symposium on Prediction and Decision Making 2015
- Place of Presentation
  東京
- Year and Date
  2015-10-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] Nucleus accumbens plays a role in arm choice behavior in the rodent gambling test2015
- Author(s)
  Mizoguchi H, Inutsuka A, Hikida T, Yamanaka A, Yamada K.
- Organizer
  2015年包括脳ネットワーク冬のシンポジウム
- Place of Presentation
  東京
- Year and Date
  2015-12-17
- Data Source
  KAKENHI-PUBLICLY-26120713
[Presentation] 基礎研究から探る薬物依存者の意思決定：リスク回避より目先の利益を優先する近視眼的意思決定2015
- Author(s)
  溝口博之、山田清文
- Organizer
  平成27年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  神戸
- Year and Date
  2015-10-11
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] Nicotine receptor as a potential target for treatment of pathological decision-making in addiction2015
- Author(s)
  Mizoguchi H, Yamada K.
- Organizer
  WPAIC 2015, 4th Asian Congress of Schizophrenia Research, 4th Congress of Asian College of Neuropsychopharmacology
- Place of Presentation
  Taipei
- Year and Date
  2015-11-18
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26120713
[Presentation] Nicotine receptor as a potential target for treatment of pathological decision-making in addiction2015
- Author(s)
  Mizoguchi H, Yamada K.
- Organizer
  WPAIC 2015, 4th Asian Congress of Schizophrenia Research, 4th Congress of Asian College of Neuropsychopharmacology
- Place of Presentation
  Taipei
- Year and Date
  2015-11-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] 基礎研究から探る薬物依存者の意思決定：リスク回避より目先の利益を優先する近視眼的意思決定2015
- Author(s)
  溝口博之、山田清文
- Organizer
  平成27年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  神戸
- Year and Date
  2015-10-11
- Data Source
  KAKENHI-PUBLICLY-26120713
[Presentation] Nucleus accumbens plays a role in arm choice behavior in the rodent gambling test2015
- Author(s)
  Mizoguchi H, Inutsuka A, Hikida T, Yamanaka A, Yamada K.
- Organizer
  2015年包括脳ネットワーク冬のシンポジウム
- Place of Presentation
  東京
- Year and Date
  2015-12-17
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] The insular GABAergic system controls decision-making in healthy and drug-dependent animals.2015
- Author(s)
  Mizoguchi H, Yamada K.
- Organizer
  IBNS 24th Annual Meeting
- Place of Presentation
  Victoria
- Year and Date
  2015-06-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] 基礎研究から探る薬物依存者の意思決定：リスク回避より目先の利益を優先する近視眼的意思決定2015
- Author(s)
  溝口博之、山田清文
- Organizer
  平成27年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  神戸国際会議場（神戸市中央区）
- Year and Date
  2015-10-11
- Data Source
  KAKENHI-PROJECT-26293053
[Presentation] Decision making in methamphetamine-treated rat.2013
- Author(s)
  H. Mizoguchi, K. Fukumoto, T. Wang, J. Sato, K. Yamada
- Organizer
  The 22rd Annual Meeting of International Behavioral Neuroscience Society
- Place of Presentation
  ダブリン
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] Neuronal mechanism of impaired decision-making in an animal model of methamphetamine dependence.2013
- Author(s)
  H. Mizoguchi, K. Yamada
- Organizer
  International symposium of “Prediction and Decision Making” 2013
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation]2012
- Author(s)
  溝口博之、山田清文
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23659135
[Presentation]2012
- Author(s)
  Mizoguchi H, Yamada K
- Organizer
  2012 ISBRA World congress
- Place of Presentation
  札幌札幌コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23659135
[Presentation]2012
- Author(s)
  山田清文、溝口博之
- Organizer
  平成 24 年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  札幌札幌コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23659135
[Presentation] ニコチンの認知機能改善作用2012
- Author(s)
  山田清文、溝口博之
- Organizer
  平成 24 年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790082
[Presentation] 覚せい剤は報酬の利得・損失の評価異常を引き起こす.2012
- Author(s)
  溝口博之
- Organizer
  第 35 回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23790082
[Presentation] 覚せい剤は報酬の利得・損失の評価異常を引き起こす2012
- Author(s)
  溝口博之、山田清文
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23790082
[Presentation] Alteration of decision-making behavior is related to the overestimation of risk / benefit values in methamphetamine-treated rats.2012
- Author(s)
  Mizoguchi H
- Organizer
  2012 ISBRA World congress
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790082
[Presentation]2012
- Author(s)
  Yamada K, Ibi D, Nakajima A, Yamada S, Mizoguchi H, Nabeshima T and Nagai T
- Organizer
  8thFENS Forum of Neuroscience
- Place of Presentation
  Barcelona International Convention Center
- Data Source
  KAKENHI-PROJECT-22390046
[Presentation] Alteration of decision-making behavior is related to the overestimation of risk / benefit values in methamphetamine-treated rats2012
- Author(s)
  Mizoguchi H, Yamada K
- Organizer
  2012 ISBRA World congress
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790082
[Presentation] 報酬に基づく意思決定機構に対する覚せい剤の効果2011
- Author(s)
  溝口博之、山田清文
- Organizer
  第21回日本臨床精神薬理学会、第41回日本神経精神薬理学会合同年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790082
[Presentation] 報酬に基づく意思決定に対するmethamphetamineの影響2011
- Author(s)
  溝口博之、山田清文
- Organizer
  第120回日本薬理学会近畿部会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23790082
[Presentation] 報酬に基づく意思決定機構に対する覚せい剤の効果2011
- Author(s)
  溝口博之、山田清文
- Organizer
  平成 23 年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23790082
[Presentation] 意思決定の行動学的解析:放射状迷路を用いた小動物用ギャンブルテスト2010
- Author(s)
  溝口博之、他
- Organizer
  第118回日本薬理学会近畿部会
- Place of Presentation
  大阪
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-21790068
[Presentation] ラットを用いた意思決定の行動学的解析:放射状迷路を用いた小動物用ギャンブルテスト2010
- Author(s)
  溝口博之、他
- Organizer
  第45回日本アルコール・薬物医学会、第22回日本アルコール精神医学会、第13回ニコチン・薬物依存研究フォーラム
- Place of Presentation
  福岡
- Year and Date
  2010-10-09
- Data Source
  KAKENHI-PROJECT-21790068
[Presentation] Beneficial treatment of nicotine in methamphetamine (METH)-induced impairment of sensormotor gating2009
- Author(s)
  Mizoguchi H, et al.
- Organizer
  Society for Neuroscience2009
- Place of Presentation
  Nagoya, Japan
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] Involvement of matrix metalloproteinase-9 in the development of pentyl eneterazole-induced kindled seizure in mice.2009
- Author(s)
  Hiroyuki Mizoguchi, et al.
- Organizer
  Neuro2009 Satellite Symposium The 4th MCCS-Asia symposium
- Place of Presentation
  名古屋
- Year and Date
  2009-09-15
- Data Source
  KAKENHI-PROJECT-21790068
[Presentation] Involvement of matrix metalloproteinase-9 in the development of pentylenetetrazole-induced kindled seizure in mice2009
- Author(s)
  Mizoguchi H, et al.
- Organizer
  The4th MCCS-Asia Symposium
- Place of Presentation
  Nagoya, Japan
- Year and Date
  2009-09-15
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] 統合失調症様認知障害モデル動物におけるGABAB受容体作用薬の有効性. (アニュアルシンポジウム「統合失調症の創薬をめざして」)2008
- Author(s)
  溝口博之, 他
- Organizer
  第51回日本神経化学会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] 覚せい剤誘発認知障害におけるGABA_B受容体アゴニストの効果2008
- Author(s)
  溝口博之, 他
- Organizer
  第11回ニコチン・薬物依存研究フォーラム
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] メタンフェタミン連続投与による異常行動とマトリクスメタロプロテアーゼの生理活性変化2007
- Author(s)
  溝口博之, 山田清文, 丹羽美苗, 毛利彰宏, 水野朋子, 野田幸裕, 新田淳美, 糸原重美, 坂野喜子, 鍋島俊隆
- Organizer
  第42回日本アルコール・薬物医学会, 第19回日本アルコール精神医学会, 第10回ニコチン・薬物依存研究フォーラム合同学術総会
- Place of Presentation
  滋賀県、大津市
- Year and Date
  2007-09-28
- Data Source
  KAKENHI-PROJECT-18790052
[Presentation] Implication of matrix metalloprotease-9 in cognitive impairment induced by i.c.v. injection of Aβ in mice.2007
- Author(s)
  Mizoguchi H, et. al.
- Organizer
  The 2nd MCCS-Asia Symposium (Neuro2007 Satellite Symposium)
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] 覚せい剤による依存・精神病性障害と認知機能障害における組織プラスミノーゲン活性化因子の関与(シンポジウム「アルコール・薬物依存の基礎研究の動向」).2007
- Author(s)
  山田清文, 永井拓, 溝口博之, 鍋島俊隆, 田熊一敞
- Organizer
  第42回日本アルコール・薬物医学会, 第19回日本アルコール精神医学会, 第10回ニコチン・薬物依存研究フォーラム平成19年度合同学術総会.
- Place of Presentation
  大津
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] Reduction of methamphetamine-induced sensitization and reward, but not congnitive impairment, in matrix metalloproteina se-2 and-9 deficient mice.2007
- Author(s)
  Mizoguchi H, Yamada K, Niwa M, Mouri A, Mizuno T, Noda Y, Nitta A, Itohara S. Banno Y. Nabeshima T
- Organizer
  The 37th Annual meeting Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Year and Date
  2007-11-03
- Data Source
  KAKENHI-PROJECT-18790052
[Presentation] 覚せい剤依存症モデルラットの意思決定障害と島皮質
- Author(s)
  溝口博之、福本和哉、山田清文
- Organizer
  日本薬学会第１３５年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PUBLICLY-26120713
[Presentation] Neuronal mechanisms of methamphetamine-seeking behavior in mice
- Author(s)
  Yamada K, Yan Y, Nitta A, Mizoguchi H, Nabeshima T
- Organizer
  5th CINP Pacific-Asia Regional Meeting 2011
- Place of Presentation
  Kuala Lumpur, Malaysia
- Data Source
  KAKENHI-PROJECT-23659135
[Presentation] 薬物依存症の意思決定異常と島皮質
- Author(s)
  溝口博之、片平健太郎、犬束歩、大平英樹、山中章弘、山田清文
- Organizer
  第３６回日本生物学的精神医学会、第５７回日本神経化学会大会合同年会
- Place of Presentation
  奈良
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PUBLICLY-26120713
[Presentation] 島皮質は薬物依存症モデルラットの意思決定に関与する
- Author(s)
  溝口博之、山田清文
- Organizer
  第８８回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PUBLICLY-26120713
[Presentation] 覚せい剤依存モデル動物の近視眼的意思決定と島皮質障害.
- Author(s)
  溝口博之、福本和哉、山田清文
- Organizer
  平成25年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  岡山
- Invited
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] 島皮質は薬物依存症モデルラットの意思決定に関与する
- Author(s)
  溝口博之、山田清文
- Organizer
  第８８回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] Reward-based decision-making in methamphetamine-dependent rat.
- Author(s)
  Mizoguchi H., Fukumoto K., Wang T., Yamada K.
- Organizer
  ９th Federation of European Neuroscience Societies, Forum of Neuroscience
- Place of Presentation
  ミラノ
- Year and Date
  2014-07-05 – 2014-07-09
- Data Source
  KAKENHI-PUBLICLY-26120713
[Presentation] 薬物依存症の意思決定異常と島皮質
- Author(s)
  溝口博之、片平健太郎、犬束　歩、大平英樹、山中章弘、山田清文
- Organizer
  第36回日本生物学的精神医学会、第57回日本神経化学会大会合同年会
- Place of Presentation
  奈良
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] Dysfunction of GABAergic system in the insular cortex is associated with impaired decision-making in methamphetamine-treated rats
- Author(s)
  Yamada K., Fukumoto K., Wang T., Mizoguchi H.
- Organizer
  29th CINP World Congress of Neuropsychopharmacology
- Place of Presentation
  バンクーバー
- Year and Date
  2014-06-22 – 2014-06-26
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] Dysfunction of GABA ergic system in the insular cortex is associated with impaired decision-making in methamphetamine-treated rats.
- Author(s)
  Yamada K, Fukumoto K, Wang T, Mizoguchi H
- Organizer
  29th CINP World Congress of Neuropsychopharmacology
- Place of Presentation
  バンクーバー（カナダ）
- Year and Date
  2014-06-22 – 2014-06-26
- Data Source
  KAKENHI-PROJECT-26293053
[Presentation] Dysfunction of GABAergic system in the insular cortex is associated with impaired decision-making in mehtamphetamine-treated rats
- Author(s)
  Yamada K., Fukumoto K., Wang T., Mizoguchi H.
- Organizer
  29th CINP World Congress of Neuropsychopharmacology
- Place of Presentation
  バンクーバー
- Year and Date
  2014-06-22 – 2014-06-26
- Data Source
  KAKENHI-PUBLICLY-26120713
[Presentation] Reward-Based Decision-making in methamphetamine-dependent rat.
- Author(s)
  Mizoguchi H., Fukumoto K., Wang T., Yamada K.
- Organizer
  9th Federation of European Neuroscience Societies, Forum of Neuroscience
- Place of Presentation
  ミラノ
- Year and Date
  2014-07-05 – 2014-07-09
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] Dysfunction of gabaergic system in the insular cortex contributes to impairments of decision-making in methamphetamine-depandent rats.
- Author(s)
  Yamada K, Mizoguchi H
- Organizer
  ISAM2014
- Place of Presentation
  神奈川県横浜市　パシフィコ横浜
- Year and Date
  2014-10-02 – 2014-10-06
- Data Source
  KAKENHI-PROJECT-26293053
[Presentation] 報酬に基づく意思決定機構に対する覚せい剤の効果
- Author(s)
  溝口博之、佐藤　純、山田清文
- Organizer
  平成23年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23790082
[Presentation] DERADDシステムで報酬に基づく意思決定行動を操作する.
- Author(s)
  溝口博之、福本和哉、犬束歩、山中章弘、山田清文
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] 報酬に基づく意思決定機構に対する覚せい剤の効果：放射状迷路を用いた小動物用ギャンブルテスト
- Author(s)
  溝口博之、福本和哉、Erika Toth、佐藤　純、山田清文
- Organizer
  第２１回日本臨床精神神経薬理学会、第４１回日本神経精神薬理学会合同年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790082
[Presentation] 覚せい剤依存症モデルラットの意思決定障害と島皮質
- Author(s)
  溝口博之、福本和哉、山田清文
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] 報酬に基づく意思決定機構に対する覚せい剤の効果
- Author(s)
  溝口博之、佐藤純、山田清文
- Organizer
  平成23年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  名古屋、愛知県産業労働センター
- Data Source
  KAKENHI-PROJECT-23659135

1. YAMADA Kiyofumi (30303639)

# of Collaborated Projects: 7 results

# of Collaborated Products: 53 results
2. NAGAI Taku (10377426)

# of Collaborated Projects: 6 results

# of Collaborated Products: 17 results
3. TAKUMA Kazuhiro (90289025)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
4. YAMANAKA Akihiro (60323292)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
5. 片平健太郎 (60569218)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
6. KANOU Yasuhiko (50252292)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. HIBI Yoko (70295616)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 犬束歩 (30584776)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 松崎哲郎 (80866450)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. OHIRA hideki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. OHMURA Yu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. TAKAO Kohno

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. KATANOSAKA Yuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 佐原成彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 片野坂公明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Mizoguchi Hiroyuki 溝口 博之

MIZOGUCHI Hiroyuki 溝口 博之

溝口 博之 ミゾグチ ヒロユキ

Research Projects

Research Products

Co-Researchers

Study on the regulation mechanism of neural spine morphology and cognitive function by twinfilin-1

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Development of new behavioral systems for investigating the mechanism of pleasure in food eatingPrincipal Investigator

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Genomic analysis-based neuropharmacological study on basal ganglia-thalamocortical circuits for new drug discovery in schizophrenia

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Research on decision-making and reinforcement learning in animal model of gambling disorder using a mixture of model-free and model-based reinforcement learning taskPrincipal Investigator

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不確実な状況下における報酬動機づけメカニズムとオレキシン神経活動Principal Investigator

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Neural basis of risky decision-making: Behavior, neural manipulation, computational approachesPrincipal Investigator

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オレキシン神経特異的機能操作による動機づけ神経回路の解明と意志力検証技術の開発Principal Investigator

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Research on neural circuit in decision-making by using cell- and projection-specific manner of chemogenetics and computational approachPrincipal Investigator

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A novel behavioral task for investigating a mixture of model-free and model-based reinforcement learning in rodentsPrincipal Investigator

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DREADDシステムと計算論的手法を用いた近視眼的意思決定の追究Principal Investigator

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Research Institution

Study on the neuronal circuit and molecular mechanis underlying decision-making and its application for drug development

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Effect of nicotine on reward-based decision-making in healthy and methamphetamine-treated ratPrincipal Investigator

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Effect of drugs of abuse on reward-based decision-making in rodents

Principal Investigator

Mizoguchi Hiroyuki 溝口博之

MIZOGUCHI Hiroyuki 溝口博之

溝口博之ミゾグチヒロユキ