Yanagihara Akihiro 柳原晃弘

… Alternative Names

YANAGIHARA Akihiro 柳原晃弘

KATO Akihiro 加藤晃弘

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Researcher Number	70423051
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立がん研究センター, 研究所, 主任研究員
Affiliation (based on the past Project Information) *help	2022 – 2023: 国立研究開発法人国立がん研究センター, 研究所, 主任研究員 2019 – 2021: 東北医科薬科大学, 医学部, 助教 2016 – 2017: 東北医科薬科大学, 医学部, 助教 2006 – 2015: 京都大学, 放射線生物研究センター, 研究員 2011: 京都大学, 放射性生物研究センター, 研究員
Review Section/Research Field	Principal Investigator Risk sciences of radiation/Chemicals / Basic Section 63020:Radiation influence-related / Risk sciences of radiation and chemicals Except Principal Investigator Risk sciences of radiation and chemicals / Risk sciences of radiation/Chemicals
Keywords	Principal Investigator 放射線 / DNA修復 / DNA二重鎖切断 / ライブセルイメージング / NBS1 / 細胞・組織 / 蛋白質 / 核酸 / ゲノム / ナイミーヘン症候群 / 相同組換え … More Except Principal Investigator … More NBS1 / 相同組換え / 非相同末端再結合 / クロマチン・リモデリング / 損傷乗越えDNA合成 / 放射線 / DNA修復 / 小頭症 / DNA複製 / DNA修復制御 / ナイメーヘン症候群 / RAD18ドメイン / ドメイン解析 / DNA損傷 / 非相同末端結合 / レポーター遺伝子 / 相同組み換え修復 / FACT / ATM / RAD18 / RNF20 / 損傷乗り越えDNA合成 / トポイソメレース阻害剤 / 多環芳香族炭化水素付加体 / 感興変異原 / DNA鎖架橋 / 紫外線 / 二重鎖切断 / SMC1 / H2AX リン酸化 / DNA 修復 / 環境変異原 / クロマチンリモデリング / H2Bユビキチン化 / 損傷乗り越え合成 / DNA二重鎖切断 / 環境変異原,NBS1 / H2AXリン酸化 / 複製阻害 Less

DNA二重鎖切断修復過程の可視化によるゲノム変異生成メカニズムの解明Principal Investigator
- Principal Investigator
  
  柳原晃弘
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  National Cancer Center Japan
Development and Application of a Monitoring System for Non-Homologous End Joining Proteins Using Novel Visualization Techniques.Principal Investigator
- Principal Investigator
  
  Yanagihara Akihiro
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  National Cancer Center Japan
  Tohoku Medical and Pharmaceutical University
Regulation of DNA repair pathway choice by early DNA damage response factors.Principal Investigator
- Principal Investigator
  
  YANAGIHARA Akihiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Tohoku Medical and Pharmaceutical University
  Kyoto University
Role of NBS1 C-terminal domain in genomic stability
- Principal Investigator
  
  Komatsu Kenshi
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kyoto University
Generation of ES cells to meseare DNA repair activity with reporter genes
- Principal Investigator
  
  KOBAYASHI Junya
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kyoto University
Molecular function of NBS1 in non-homologous end joining and mechanisms of chromosome instability.Principal Investigator
- Principal Investigator
  
  KATO Akihiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kyoto University
Roles of newly discovered NBS1 domains in ubiquitin signals and rejoining of double-strand breaks after irradiation
- Principal Investigator
  
  KOMATSU Kenshi
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kyoto University
Analysis of a new mechanism on homology-dependent repairPrincipal Investigator
- Principal Investigator
  
  KATO Akihiro
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kyoto University
Establishment of sensor complex of DNA double-strand breaks in vitroand analysis of initial steps in mammalian cellsPrincipal Investigator
- Principal Investigator
  
  KATO Akihiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kyoto University
Induction of DNA double strand break by environmental genotoxic and carcinogenic agents
- Principal Investigator
  
  KOMATSU Kenshi
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kyoto University

All 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Book

[Book] 光と生命の事典2016
- Author(s)
  加藤晃弘、秋山（張）秋梅、安倍学、蟻川謙太郎、安東宏徳、飯郷雅之、飯野盛利、池内昌彦、池田憲昭、池田啓、池畑広伸、井澤毅、石川大太郎、石川満、石田斉、石塚徹、井上圭一、井上幸次、伊吹裕子、今井啓雄
- Total Pages
  435
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-15K00536
[Book] 日本臨牀　73/増刊6　家族性腫瘍学2015
- Author(s)
  加藤晃弘、柳原啓見、小松賢志、石岡千加史、冨田尚裕、野水整、吉田輝彦、宇都宮譲二、福嶋義光、山内泰子、水谷修紀、谷内江昭宏、東元健、福岡みずき、玉井裕也、田中潔、向井徳男、池田史圭、小林宏寿、芦田敦子
- Total Pages
  607
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-15K00536
[Book] Nijmegen Breakage Syndrome (ナイミーヘン症候群)2015
- Author(s)
  加藤晃弘、柳原啓見、小松賢志
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-26241013
[Book] Nijmegen breakage syndrome(ナイミーヘン症候群)、「家族性腫瘍学」2015
- Author(s)
  加藤晃弘、柳原啓見、小松賢志
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-26241013
[Book] 先天代謝異常症候群（第二版）2012
- Author(s)
  柳原啓見
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-23241021
[Journal Article] Chronic irradiation with low-dose-rate 137Cs-γ rays inhibits NGF-induced neurite extension of PC12 cells via Ca2+/calmodulin-dependent kinase II activation.2017
- Author(s)
  Katoh S, Kobayashi J, Umeda T, Kobayashi Y, Nobuo I and Suzuki T
- Journal Title
  
  J Radiat Res
  
  Volume: 58 Issue: 6 Pages: 809-815
- DOI
  10.1093/jrr/rrx032
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26241013, KAKENHI-PROJECT-15H02819, KAKENHI-PROJECT-15K00545
[Journal Article] NBS1 is regulated by two kind of mechanisms; ATM-dependent complex formation with MRE11 and RAD50 and cell cycle dependent-degradation of protein.2017
- Author(s)
  Zhou H, Kawamura K, Yanagihara H, Kobayashi J, Zhang-Akiyama Q.
- Journal Title
  
  J Radiat Res.
  
  Volume: 59 Issue: 4 Pages: 1-8
- DOI
  10.1093/jrr/rrx014
- NAID
  120006647308
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26241013, KAKENHI-PROJECT-15H02819, KAKENHI-PROJECT-16K00545
[Journal Article] Induction of Excess Centrosomes in Neural Progenitor Cells during the Development of Radiation-Induced Microcephaly.2016
- Author(s)
  Shimada M, Matsuzaki F, Kato A, Kobayashi J, Matsumoto T, Komatsu K.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 7 Pages: e0158236-e0158236
- DOI
  10.1371/journal.pone.0158236
- NAID
  120006348291
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26241013, KAKENHI-PROJECT-15H02819
[Journal Article] Xray Irradiation Promotes Nerve Growth Factor-induced Neurite Extension in PC12 Cells.2016
- Author(s)
  Katoh S, kobayashi J, Umeda T, Kobayashi Y, Izumo N, Suzuki T.
- Journal Title
  
  Radioisotopes
  
  Volume: 65 Pages: 137-1432016
- NAID
  130005137587
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26241013
[Journal Article] RNF20-SNF2H pathway of chromatin relaxation in DNA double-strand break repair2015
- Author(s)
  Akihiro Kato, Kenshi Komatsu
- Journal Title
  
  Genes
  
  Volume: 6 Issue: 3 Pages: 592-606
- DOI
  10.3390/genes6030592
- NAID
  120005756286
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00536, KAKENHI-PROJECT-26241013, KAKENHI-PROJECT-26550025
[Journal Article] Hypergonadotropic Hypogonadism and Hypersegmented Neutrophils in a Patient with Ataxia-Telangiectasia-Like Disorder: Potential Diagnostic Clues?2014
- Author(s)
  Yoshida T, Awaya T, Shibata M, Kato T, Numabe H, Kobayashi K, Komatsu K, Heike T
- Journal Title
  
  Am J Med Genet A
  
  Volume: 164
- NAID
  120005456013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241021
[Journal Article] Histone chaperone FACT regulates homologous recombination by chromatin remodeling through interaction with RNF20.2014
- Author(s)
  Oliveira DV, Kato A, Nakamura K, Ikura T, Okada M, Kobayashi J, Yanagihara H, Saito Y, Tauchi H, Komatsu K
- Journal Title
  
  J Cell Sci
  
  Volume: 127 Pages: 763-772
- DOI
  10.1242/jcs.135855
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-22131001, KAKENHI-PLANNED-22131004, KAKENHI-PROJECT-23241021, KAKENHI-PROJECT-23510061, KAKENHI-PROJECT-24310038, KAKENHI-PROJECT-24510070, KAKENHI-PUBLICLY-25112513, KAKENHI-PROJECT-25550025, KAKENHI-PROJECT-25550026, KAKENHI-PROJECT-26241013, KAKENHI-PROJECT-26550025
[Journal Article] Hypergonadotropic Hypogonadism and Hypersegmented Neutrophils in a Patient with Ataxia-Telangiectasia-Like Disorder: Potential Diagnostic Clues?2014
- Author(s)
  Yoshida T, Kobayashi J, et al.
- Journal Title
  
  Am J Med Genet A
  
  Volume: 164A Issue: 7 Pages: 1830-1834
- DOI
  10.1002/ajmg.a.36546
- NAID
  120005456013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24310041, KAKENHI-PUBLICLY-25112513, KAKENHI-PROJECT-25550025, KAKENHI-PROJECT-26241013, KAKENHI-PROJECT-26550025
[Journal Article] The proteasome factor Bag101 binds to Rad22 and suppresses homologous recombination.2013
- Author(s)
  Saito Y, Takeda J, Okada M, Kobayashi J, Kato A, Hirota K, Taoka M, Matsumoto T, Komatsu K, Isobe T.
- Journal Title
  
  Sci Rep.
  
  Volume: 3 Issue: 1 Pages: 2022-2022
- DOI
  10.1038/srep02022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23221005, KAKENHI-PROJECT-23241021, KAKENHI-PUBLICLY-24114509, KAKENHI-PUBLICLY-25112513, KAKENHI-PROJECT-25281021, KAKENHI-PROJECT-25550025, KAKENHI-PROJECT-25550026
[Journal Article] Regulation of homologous recombination by RNF20-dependent H2Bubiquitination2011
- Author(s)
  Nakamura K, Kato A, Kobayashi J, Yanagihara H, Sakamoto S, Oliveira D, Shimada S, Tauchi H, Suzuki H, Tashiro S, Zou L, Komatsu K.
- Journal Title
  
  Mol Cell
  
  Volume: 41 Issue: 5 Pages: 515-528
- DOI
  10.1016/j.molcel.2011.02.002
- NAID
  130007000484
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310035, KAKENHI-PROJECT-22710053, KAKENHI-PROJECT-22710054
[Journal Article] Regulation of Homologous Recombination by RNF20-Dependent H2B Ubiquitination2011
- Author(s)
  中村恭介、加藤晃弘, et.al
- Journal Title
  
  Molecular Cell
  
  Volume: Volume 41 Pages: 515-528
- NAID
  130007000484
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710053
[Journal Article] HERC2 Interacts with Claspin and regulates DNA origin firingandr eplication fork progression2011
- Author(s)
  Izawa N, Wu W, Sato K, Nishikawa H, Kato A, Boku N, Itoh F, Ohta T
- Journal Title
  
  Cancer Research
  
  Volume: Volume 71 Issue: 17 Pages: 5621-5625
- DOI
  10.1158/0008-5472.can-11-0385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710053, KAKENHI-PUBLICLY-23131514, KAKENHI-PROJECT-23300358, KAKENHI-PROJECT-23590348
[Journal Article] Genistein, isoflavonoids in soybeans, prevents the formation of excess radiation-induced centrosomes via p21up-regulation2011
- Author(s)
  Shimada M, Kato A, Habu T, Komatsu K
- Journal Title
  
  Mutatation Research
  
  Volume: Volume 716 Issue: 1-2 Pages: 27-32
- DOI
  10.1016/j.mrfmmm.2011.07.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710053, KAKENHI-PROJECT-22710054, KAKENHI-PROJECT-23241021, KAKENHI-PROJECT-23501267, KAKENHI-PROJECT-23651045
[Journal Article] NBS1 recruits RAD18 via aRAD6-like domain and regulates Polη-dependent translesion DNA synthesis2011
- Author(s)
  Yanagihara H, Kobayashi J, Tateishi S, Kato A, Matsuura S, Tauchi H, Yamada K, Takezawa J, Sugasawa K, Masutani C, Hanaoka F, Weemaes CM, Mori T, Zou L, Komatsu K.
- Journal Title
  
  Mol Cell
  
  Volume: 43 Issue: 5 Pages: 788-797
- DOI
  10.1016/j.molcel.2011.07.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310035, KAKENHI-PUBLICLY-22019026, KAKENHI-ORGANIZER-22131001, KAKENHI-PLANNED-22131008, KAKENHI-PROJECT-22651018, KAKENHI-PROJECT-22710053, KAKENHI-PROJECT-23241021, KAKENHI-PROJECT-23651045, KAKENHI-PROJECT-22249005
[Journal Article] Regulation of homologous recombination by RNF20-dependent H2B ubiquitination2011
- Author(s)
  K.Nakamura, A.Kato, J.Kobayashi, H.Yanagihara, S.Sakamoto, D.V.N.P.Oliveira, M.Shimada, H.Tauchi, H.Suzuki, S.Tashiro, L.Zou, K.Komatsu.
- Journal Title
  
  Molecular Cell 41
  
  Pages: 515-628
- NAID
  130007000484
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Application of the DNA adductome approach to assess the DNA-damaging capability of in vitro micronucleus test-positive compounds2011
- Author(s)
  Kato, K., Yamamura, E., Kawanishi, M., Yagi, T., Matsuda, T., Sugiyama, A., Uno.Y.
- Journal Title
  
  Mutat.Res. 721
  
  Pages: 21-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Mutations of optineurin in amyotrophic lateral sclerosis.2010
- Author(s)
  Maruyama H, Morino H, Ito H, Izumi Y, Kato H, Watanabe Y, Kinoshita Y, Kamada M, Nodera H, Suzuki H, Komure O, Matsuura S, Kobatake K, Morimoto N, Abe K, Suzuki N, Aoki M, Kawata A, Hirai T, Kato T, Ogasawara K, Hirano A, Takumi T, Kusaka H, Hagiwara K, Kaji R, Kawakami H.
- Journal Title
  
  Nature 465
  
  Pages: 223-226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Bisbenzamidine derivative, pentamidine represses DNA damage response through inhibition of histone H2A acetylation.2010
- Author(s)
  J.Kobayashi, A.Kato, Y.Ota, R.Ohba, K.Komatsu.
- Journal Title
  
  Mol.Cancer 9
  
  Pages: 34-34
- NAID
  120002515185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Deletion of a novel F-box protein, MUS-10, in Neurospora crassa leads to altered mitochondrial morphology, instability of mtDNA and senescence.2010
- Author(s)
  A.Kato, K.Kurashima, M.Chae, S.Sawada, S.Hatakeyama, S.Tanaka, H.Inoue.
- Journal Title
  
  Genetics. 185
  
  Pages: 1257-1269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Genotoxicity of nano/microparticles in in vitro micronuclei, in vivo comet and mutation assay systems2009
- Author(s)
  Totsuka, Y., Higuchi, T., Imai, T., Nishikawa, A., Nohmi, T., Kato, T., Masuda, S., Kinae, N., Hiyoshi, K., Ogo, S., Kawanishi, M., Yagi, T Ichinose, T., Sugimura, T., Wakabayashi, K.
- Journal Title
  
  Particle fibre toxicol. 6(23)
  
  Pages: 6-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Neurosprora crassa RAD5 homologue, mus-41, inactivation results in higher sensitivity to mutagens but has little effect on PCNA-ubiquitylation in response to UV-irradiation.2007
- Author(s)
  T Kawabata, A.Kato, K.Suzuki, H.Inoue.
- Journal Title
  
  Current Genetics 52
  
  Pages: 125-135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Identification and comparative analysis of the large subunit mitochondrial ribosomal proteins of Neurospora crassa.2006
- Author(s)
  X.Gan, K.Arita, S.Isono, M.Kitakawa, K.Yoshino, K.Yonezawa, A.Kato, H.Inoue, K.Isono.
- Journal Title
  
  FEMS Microbiology Letters 254(1)
  
  Pages: 157-164
- NAID
  120000949817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Presentation] 日本人AT-LD患者におけるMRE11変異部位とDNA損傷応答異常との関係2017
- Author(s)
  河村香寿、Qi Fei、加藤竹雄、松浦伸也、小松賢志、小林純也
- Organizer
  日本放射線影響学会第60回大会
- Data Source
  KAKENHI-PROJECT-26241013
[Presentation] NBS1 の新規 C 末端ドメインは NHEJ の亢進に関与する2017
- Author(s)
  加藤晃弘、柳原啓見、小松賢志
- Organizer
  第34回染色体ワークショップ・第15回核ダイナミクス研究会
- Place of Presentation
  かずさアカデミアホール（千葉県・木更津市）
- Year and Date
  2017-01-12
- Data Source
  KAKENHI-PROJECT-15K00536
[Presentation] NBS1 の新規 C 末端ドメインは NHEJ の亢進に関与する2017
- Author(s)
  加藤晃弘、柳原啓見、小松賢志
- Organizer
  第34回染色体ワークショップ・第15回核ダイナミクス研究会
- Place of Presentation
  木更津市
- Year and Date
  2017-01-11
- Data Source
  KAKENHI-PROJECT-26241013
[Presentation] Oxidative stress and DNA damage responses under low dose rate irradiation2016
- Author(s)
  Kobayashi J, Saito Y, Kato A, Oliveira DV, Yanagihara H, Matsuura S, Komatsu K.
- Organizer
  The 2nd KU RBC-CEA Joint Workshop
- Place of Presentation
  Kyoto.
- Year and Date
  2016-04-11
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26241013
[Presentation] NBS1 controls homologous recombination and non-homologous end joining in different ways.2016
- Author(s)
  Akihiro Kato, Hiromi Yanagihara, and Kenshi Komatsu
- Organizer
  The 10th International 3R Symposium
- Place of Presentation
  ホテル一畑（島根県・松江市）
- Year and Date
  2016-11-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00536
[Presentation] NBS1 controls homologous recombination and non-homologous end joining in different ways.2016
- Author(s)
  Akihiro Kato, Hiromi Yanagihara, and Kenshi Komatsu.
- Organizer
  The 10th International 3R Symposium
- Place of Presentation
  Matue
- Year and Date
  2016-04-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26241013
[Presentation] Functional analysis of the novel C-terminus domain of NBS1.2015
- Author(s)
  Kato A. Komatsu K
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26241013
[Presentation] Analysis of the novel functional domain of NBS1.2015
- Author(s)
  Akihiro Kato, Hiromi Yanagihara and Kenshi Komatsu
- Organizer
  ICRR2015
- Place of Presentation
  京都
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00536
[Presentation] Dose-dependent regulation of two rejoining pathways for DNA double-strand breaks.2015
- Author(s)
  Yuichiro Saito, Makoto Ihara, Akihiro Kato, Junya Kobayashi, Kenshi Komatsu.
- Organizer
  30th RBC-NIRS International Symposium
- Place of Presentation
  京都
- Year and Date
  2015-02-20
- Invited
- Data Source
  KAKENHI-PROJECT-26241013
[Presentation] Functional analysis of the novel C-terminus domain of NBS1.2015
- Author(s)
  Akihiro Kato and Kenshi Komatsu
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K00536
[Presentation] Regulation of various DNA damage responses through complex formations of NBS1.2015
- Author(s)
  Kobayashi J, Saito Y, Kato A, Oliveira DV, Yanagihara H, Matsuura S, Komatsu K.
- Organizer
  16th Ataxia-Telangiectasia Workshop
- Place of Presentation
  Beijing
- Year and Date
  2015-10-11
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26241013
[Presentation] NBS1蛋白C末側ドメインとDNA損傷応答における役割2014
- Author(s)
  小松賢志、加藤晃弘、柳原啓見、斎藤裕一朗、周慧、小林純也
- Organizer
  日本放射線影響学会第57回大会
- Place of Presentation
  鹿児島
- Year and Date
  2014-10-01
- Invited
- Data Source
  KAKENHI-PROJECT-24510070
[Presentation] 相同組換え修復と損傷乗越えDNA合成におけるNBS1蛋白の役割2014
- Author(s)
  小松賢志、加藤晃弘、柳原啓見、斎藤裕一朗、周慧、小林純也
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25
- Invited
- Data Source
  KAKENHI-PROJECT-24510070
[Presentation] NBS1蛋白C末側ドメインとDNA損傷応答における役割2014
- Author(s)
  小松賢志、加藤晃弘、柳原啓見、斎藤裕一朗、周慧、小林純也
- Organizer
  日本放射線影響学会
- Place of Presentation
  鹿児島
- Year and Date
  2014-10-01
- Invited
- Data Source
  KAKENHI-PROJECT-26241013
[Presentation] NBS1 plays a role in UV damage response through physical interaction with RAD18.2014
- Author(s)
  A Kato, H Yanagihara, J Kobayashi, Y Saito, D Oliveira, C Weemaes, and K Komatsu
- Organizer
  International Symposium on Xeroderma Pigmentosum and Related Diseases: Disorders of DNA Damage Response -Bench to Bedside
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24510070
[Presentation] 相同組換え修復と損傷乗越えDNA合成におけるNBS1蛋白の役割2014
- Author(s)
  小松賢志、加藤晃弘、柳原啓見、斎藤裕一朗、周慧、小林純也
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25
- Invited
- Data Source
  KAKENHI-PROJECT-26241013
[Presentation] NBS1 plays a role in UV damage response through physical interaction with RAD182014
- Author(s)
  A Kato, H Yanagihara, J Kobayashi, Y Saito, D Oliveira, C Weemaes, and K Komatsu.
- Organizer
  International Symposium on Xeroderma Pigmentosum and Related Diseases
- Place of Presentation
  Kobe
- Invited
- Data Source
  KAKENHI-PROJECT-23241021
[Presentation] NBS1による損傷乗り越えDNA合成開始機構とモデルマウスの開発2013
- Author(s)
  柳原啓見、加藤晃弘、小林純也、斎藤裕一朗、前川貴則、谷崎美智、小松賢志
- Organizer
  日本放射線影響学会第56回大会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-23241021
[Presentation] A Kato, H Yanagihara, K Komatsu. Distinct domains of NBS1 separately function in IR- and UV-damage response.2013
- Author(s)
  A Kato, H Yanagihara, K Komatsu
- Organizer
  The DNA damage response in cell physiology and disease
- Place of Presentation
  Cape Sounio
- Data Source
  KAKENHI-PROJECT-23241021
[Presentation] Distinct domains of NBS1 separately function in IR- and UV-damage response.2013
- Author(s)
  A Kato, H Yanagihara, K Komatsu
- Organizer
  EMBO Conference The DNA damage response in cell physiology and disease
- Place of Presentation
  Cape Sounio（ギリシャ）
- Data Source
  KAKENHI-PROJECT-24510070
[Presentation] MRN複合体とRAD51の相互作用2011
- Author(s)
  加藤晃弘
- Organizer
  日本放射線影響学会第54回大会
- Place of Presentation
  神戸商工会議所会館(神戸市)
- Year and Date
  2011-11-18
- Data Source
  KAKENHI-PROJECT-22710053
[Presentation] The link between MRN complex and RAD512011
- Author(s)
  加藤晃弘
- Organizer
  ICRR2011
- Place of Presentation
  ワルシャワ(ポーランド)
- Year and Date
  2011-08-30
- Data Source
  KAKENHI-PROJECT-22710053
[Presentation] The link between MRN complex and RAD512011
- Author(s)
  加藤晃弘
- Organizer
  ICRR2011
- Place of Presentation
  ポーランド
- Year and Date
  2011-08-30
- Data Source
  KAKENHI-PROJECT-22710053
[Presentation] Physical and functional interaction between MRN complex and RAD512011
- Author(s)
  加藤晃弘
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(名古屋市)
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-22710053
[Presentation] Physical and functional interaction between MRN complex and RAD512011
- Author(s)
  加藤晃弘
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-22710053
[Presentation] MRN複合体とRAD51の相互作用2011
- Author(s)
  加藤晃弘
- Organizer
  日本放射線影響学会第54回大会
- Place of Presentation
  神戸
- Year and Date
  2011-11-18
- Data Source
  KAKENHI-PROJECT-22710053
[Presentation] The link between MRN complex and RAD512011
- Author(s)
  加藤晃弘
- Organizer
  ICRR2011
- Place of Presentation
  京都
- Year and Date
  2011-08-30
- Data Source
  KAKENHI-PROJECT-22710053
[Presentation] MRN複合体とRAD51との関係2010
- Author(s)
  加藤晃弘
- Organizer
  日本放射線影響学会第53回大会
- Place of Presentation
  京都
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-22710053
[Presentation] Control of homologous recombination by RNF20-dependent H2B ubiquitination2010
- Author(s)
  加藤晃弘
- Organizer
  EMBO workshop 「The Interface between the Ubiquitin Family and the DNA Damage Response」
- Place of Presentation
  クロアチア,ロビーニ
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-22710053
[Presentation] MRN複合体とRAD51との関係2010
- Author(s)
  加藤晃弘
- Organizer
  日本放射線影響学会第53回大会
- Place of Presentation
  大阪
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-22710053
[Presentation] RAD51がMRN複合体に結合する2010
- Author(s)
  加藤晃弘
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22710053
[Presentation] Analysis of the relationship between the MRN complex and RAD51.2010
- Author(s)
  加藤晃弘
- Organizer
  Maintenance of Genome Stability 2010
- Place of Presentation
  (Antigua and Batbuda) Bolans village
- Year and Date
  2010-03-10
- Data Source
  KAKENHI-PROJECT-22710053
[Presentation] Control of homologous recombination by RNF20-dependent H2B ubiquitination2010
- Author(s)
  加藤晃弘
- Organizer
  EMBO workshop「The Interface between the Ubiquitin Family and the DNA Damage Response」
- Place of Presentation
  クロアチア
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-22710053
[Presentation] DNA損傷応答におけるNBS1結合因子の働き2009
- Author(s)
  加藤晃弘
- Organizer
  日本放射線影響学会第52回大会
- Place of Presentation
  広島市
- Year and Date
  2009-11-12
- Data Source
  KAKENHI-PROJECT-18101002
[Presentation] NBS1 is required for UV-induced DNA damage response2008
- Author(s)
  加藤晃弘、初村裕英、小松賢志
- Organizer
  The 6th 3R Symposium
- Place of Presentation
  掛川
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19710050
[Presentation] NBS1はATRIPのフォーカス形成に必要である2008
- Author(s)
  加藤晃弘
- Organizer
  日本放射線影響学会第51回大会
- Place of Presentation
  北九州
- Year and Date
  2008-11-21
- Data Source
  KAKENHI-PROJECT-19710050
[Presentation] Role of the N-terminal region of NBS1 in ATR-mediated DNA damage response2008
- Author(s)
  加藤晃弘、初村裕英、小松賢志
- Organizer
  Maintenance of Genome Stability 2008
- Place of Presentation
  メキシコ
- Year and Date
  2008-03-05
- Data Source
  KAKENHI-PROJECT-19710050
[Presentation] The role of the N-terminal region of NBS1 in ATR-mediated DNA damage response2008
- Author(s)
  加藤晃弘
- Organizer
  Ataxia-telangiectasia Workshop 2008
- Place of Presentation
  大津
- Year and Date
  2008-04-25
- Data Source
  KAKENHI-PROJECT-19710050
[Presentation] The role of the N-terminal region of NBS1 in ATR-mediated DNA damage response2008
- Author(s)
  加藤晃弘、初村裕英、小松賢志
- Organizer
  Ataxia-Telangiectasia Workshop 2008
- Place of Presentation
  大津
- Year and Date
  2008-04-25
- Data Source
  KAKENHI-PROJECT-19710050
[Presentation] NBS1はArRIPのフォーカス形成に必要である2008
- Author(s)
  加藤晃弘、初村裕英、小松賢志
- Organizer
  日本放射線影響学会第51回大会
- Place of Presentation
  北九州
- Year and Date
  2008-11-21
- Data Source
  KAKENHI-PROJECT-19710050
[Presentation] NBS1 is required for ATRIP focus formation2008
- Author(s)
  加藤晃弘、初村裕英、小松賢志
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19710050
[Presentation] Role of the N-terminal region of NBS1 in ATR-mediated DNA damage response.2008
- Author(s)
  加藤晃弘, 他2名
- Organizer
  Maintenance of Genome Stability 2008
- Place of Presentation
  プエルトバヤルタ、メキシコ
- Year and Date
  2008-03-05
- Data Source
  KAKENHI-PROJECT-18101002
[Presentation] 紫外線損傷応答におけるNBS1の機能解析2007
- Author(s)
  柳原啓見, 他4名
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2007-12-10
- Data Source
  KAKENHI-PROJECT-18101002
[Presentation] NBS患者細胞とNbs1欠損マウス細胞の解析2007
- Author(s)
  初村裕英、加藤晃弘、松浦伸也、小松賢志
- Organizer
  日本放射線影響学会第50回大会
- Place of Presentation
  千葉
- Year and Date
  2007-11-15
- Data Source
  KAKENHI-PROJECT-19710050
[Presentation] Domain analysis of the Nbs1 gene in murine cells2007
- Author(s)
  加藤晃弘
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19710050
[Presentation] DNA損傷チェックポイントにおけるNBS1の役割2007
- Author(s)
  加藤晃弘, 他2名
- Organizer
  日本放射線影響学会第50回大会
- Place of Presentation
  千葉
- Year and Date
  2007-11-15
- Data Source
  KAKENHI-PROJECT-18101002
[Presentation] Nbs1欠損マウス細胞の解析2007
- Author(s)
  加藤晃弘、初村裕英、松浦伸也、野田哲生、小松賢志
- Organizer
  第八回文部科学省特定領域研究「がん」5領域若手研究者ワークショップ
- Place of Presentation
  長野
- Year and Date
  2007-08-30
- Data Source
  KAKENHI-PROJECT-19710050
[Presentation] 紫外線損傷応答におけるNBS1の機能解析2007
- Author(s)
  柳原啓見, 他5名
- Organizer
  日本放射線影響学会第50回大会
- Place of Presentation
  千葉
- Year and Date
  2007-11-15
- Data Source
  KAKENHI-PROJECT-18101002
[Presentation] DNA損傷チェックポイントにおけるNBS1の役割2007
- Author(s)
  加藤晃弘、初村裕英、小松賢志
- Organizer
  日本放射線影響学会第50回大会
- Place of Presentation
  千葉
- Year and Date
  2007-11-15
- Data Source
  KAKENHI-PROJECT-19710050
[Presentation] Domain analysis of the Nbs1 gene in murine cells.2007
- Author(s)
  加藤晃弘, 他4名
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-18101002
[Presentation] MRN複合体阻害による放射線増感作用の検討2007
- Author(s)
  宮口雄人、加藤晃弘、太田陽介、小林純也、小松賢志
- Organizer
  日本放射線影響学会第50回大会
- Place of Presentation
  千葉
- Year and Date
  2007-11-15
- Data Source
  KAKENHI-PROJECT-19710050
[Presentation] Domain analysis of the Nbs 1 gene in murine cells2007
- Author(s)
  加藤晃弘、柳原啓見、松浦伸也、野田哲生、小松賢志
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19710050
[Presentation] DNA二重鎖切断応答におけるNBS1の新たな機能
- Author(s)
  加藤晃弘、柳原啓見、小松賢志
- Organizer
  日本放射線影響学会第57回大会
- Place of Presentation
  鹿児島
- Year and Date
  2014-10-01 – 2014-10-03
- Data Source
  KAKENHI-PROJECT-24510070
[Presentation] Connection between MRN complex and RAD51 in homologous recombination.
- Author(s)
  Akihiro Kato and Kenshi Komatsu
- Organizer
  Mechanisms of Recombination: 50th Anniversary Meeting of the Holliday Model
- Place of Presentation
  アリカンテ（スペイン）
- Year and Date
  2014-05-19 – 2014-05-23
- Data Source
  KAKENHI-PROJECT-24510070
[Presentation] NBS1 plays a role in UV damage response through physical interaction with RAD18.
- Author(s)
  A Kato, H Yanagihara, J Kobayashi, Y Saito, D Oliveira, C Weemaes, and K Komatsu
- Organizer
  ZING Conferences DNA Polymerases
- Place of Presentation
  ケンブリッジ（イギリス）
- Year and Date
  2014-08-31 – 2014-09-03
- Data Source
  KAKENHI-PROJECT-24510070
[Presentation] RNF20-dependent H2B ubiquitination modulates repair of DNA double-strand breaks by homologous recombination.
- Author(s)
  Akihiro Kato, Kyosuke Nakamura, Junya Kobayashi, Hiromi Yanagihara, Shuichi Sakamoto, Hiroshi Tauchi, Satoshi Tashiro, Lee Zou, Kenshi Komatsu
- Organizer
  日本放射線影響学会第55回大会
- Place of Presentation
  仙台
- Invited
- Data Source
  KAKENHI-PROJECT-24510070
[Presentation] MRN複合体とRAD51の物理的・機能的相互作用の解析
- Author(s)
  加藤　晃弘、小松　賢志
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24510070

1. KOMATSU Kenshi (80124577)

# of Collaborated Projects: 4 results

# of Collaborated Products: 18 results
2. KOBAYASHI Junya (30301302)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
3. TAUCHI Hiroshi (70216597)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. MATSUURA Shinya (90274133)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
5. YAGI Takasi (80182301)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MORISIMA Kenichi (00363078)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. HONDA Hiroaki (40245064)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 槌田謙 (80397570)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 廣田耕志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 岡田徹也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 武田俊一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 青田聖恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 井倉毅

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 八木孝司

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Yanagihara Akihiro 柳原 晃弘

YANAGIHARA Akihiro 柳原 晃弘

KATO Akihiro 加藤 晃弘

Research Projects

Research Products

Co-Researchers

DNA二重鎖切断修復過程の可視化によるゲノム変異生成メカニズムの解明Principal Investigator

Principal Investigator

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Review Section

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Development and Application of a Monitoring System for Non-Homologous End Joining Proteins Using Novel Visualization Techniques.Principal Investigator

Principal Investigator

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Review Section

Research Institution

Regulation of DNA repair pathway choice by early DNA damage response factors.Principal Investigator

Principal Investigator

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Research Field

Research Institution

Role of NBS1 C-terminal domain in genomic stability

Principal Investigator

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Generation of ES cells to meseare DNA repair activity with reporter genes

Principal Investigator

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Molecular function of NBS1 in non-homologous end joining and mechanisms of chromosome instability.Principal Investigator

Principal Investigator

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Research Institution

Roles of newly discovered NBS1 domains in ubiquitin signals and rejoining of double-strand breaks after irradiation

Principal Investigator

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Analysis of a new mechanism on homology-dependent repairPrincipal Investigator

Principal Investigator

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Establishment of sensor complex of DNA double-strand breaks in vitroand analysis of initial steps in mammalian cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Induction of DNA double strand break by environmental genotoxic and carcinogenic agents

Principal Investigator

Project Period (FY)

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Research Institution

[Book] 光と生命の事典2016

Author(s)

Total Pages

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Data Source

[Book] 日本臨牀 73/増刊6 家族性腫瘍学2015

Author(s)

Total Pages

Publisher

Data Source

[Book] Nijmegen Breakage Syndrome (ナイミーヘン症候群)2015

Author(s)

Publisher

Data Source

Yanagihara Akihiro 柳原晃弘

YANAGIHARA Akihiro 柳原晃弘

KATO Akihiro 加藤晃弘

[Book] 日本臨牀　73/増刊6　家族性腫瘍学2015