Komatsu Kenshi 小松賢志

… Alternative Names

Researcher Number	80124577
Other IDs
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Affiliation (Current)	2018 : 京都大学, 生命科学研究科, 研究員
Affiliation (based on the past Project Information) *help	2015 – 2017 : 京都大学, 放射線生物研究センター, 研究員 2002 – 2014 : Kyoto University, Radiation Biology Center, Professor, 放射線生物研究センター, 教授 2002 : Kyoto University, Radiationbiology Center, Professor, 放生研, 教授 2001 : 京都大学, 放射線研究センター, 教授 2001 : 広島大学, 原医研, 教授 … More
Review Section/Research Field	Principal Investigator 環境影響評価(含放射線生物学) / Risk sciences of radiation/Chemicals / Nuclear fusion studies / Biological Sciences / Risk sciences of radiation and chemicals / 放射線5生物学 Except Principal Investigator Human genetics / 環境影響評価(含放射線生物学) / Nuclear fusion studies / Biological Sciences / 放射線5生物学 / Risk sciences of radiation and chemicals / Cerebral neurosurgery
Keywords	Principal Investigator NBS1 / ATM / DNA修復 / 放射線感受性 / 放射線 / NBS / DNA二重鎖切断 / BRCA1 / WRN / 相同組換え … More Except Principal Investigator NBS1 / 放射線感受性 / Nbs1 / p53 / DNA修復 / dsb / テロメア / NBS / 高発癌性遺伝病 / Ataxia-telangiectasia / AT / ATM / トリチウム / トリチウム水 / BUB1B / Model mouse / Xist / H2AX / V79 / 電離放射線 / 放射線 / 中性子 / 放射線高感受性 / DNA損傷 / 染色体不安定性 / Nijmegen syndrome / 細胞周期 / 生物影響 / BubR1 / Xrs2 / DNA repair / 突然変異 / モデルマウス / Rev1 / 遺伝病 / p55cdc / HPRT / 毛細血管拡張性運動失調症 / TOF / 線量評価 / Homologous recombination / フォーカス / 相同組換え / ノックアウトマウス / ナイミーヘン症候群 / トランスポゾン / 重水野外実験 / 遺伝子スイッチ / 公衆被曝 / DNA切断再結合 / focus / クロマチン損傷 / 河川のトリチウムの濃度 / エンドヌクレアーゼ / 野外実験 / Wilms腫瘍 / Radiation sensitivity / Tritium control in nuclear reactor / 2重鎖切断 / X inactivation / DNA-PK / Rodiation sensitivity / 減数分裂 / Tritium concentration in river fresh water / Radiation scnsitivity / ポジショナルクローニング / 相同組換え修復 / トランスジェニックマウス / エネルギー依存性 / Nijmegen breakage症候群 / マウス発がん / 細胞死(アポトーシス) / NBSI / エネルギースペクトル / Gene targeting / 遺伝的不安定性 / X不活化 / cellcycle / 非相同組換え / 線量測定 / PCS症候群 / DT40 cells / Positional cloning / Gene homing / 情報伝達 / Field release experiment / 細胞がん化系 / gnome instability / 自然突発異変 / signal transduction / ITER / 奇形 / DT40細胞 / Plagl1 / トラシスポゾン / 損傷乗越え修復 / Mutation / 誤りがちなDNA合成 / Nijmegen breakage syndrome / Environmental tritium / accelerator / PCS / 野外放出実験 / 中性子線 / ブルーム症候群 / 環境 / 中性子発生装置 / DNAエンドジョイニング / トランスポゼース / トリチウムガスの環境科学 / RecQヘリカーゼ / low dose and low dose-rate radiation / 二重鎖切断 / Transposon / 環境トリチウム / 適応 / DNA二本鎖切断 / 低線量・低線量率放射線 / Nijmegen症候群 / 8q21 / DN二重鎖切断 / adaptation / translesion / Illegitimate recombination / Culture cell / 相同組み換え / トリチウムの事故放出 / translesion DNA repair / MAD2 / 免疫不全 / Gene knockout / telomere / Mosaic variegated aneuploidy / Mitotic checkpoint / Sox11 / 先行指標 / Soxll / 遺伝子損傷 / Cancer prone disease / 感受性修飾 / energy spectrum / Histone H2AX / 先行指導 / PCS syndrome / ナイミ-ヘン症候群 / 放射線障害 / DNA・PK / Revl / tritium / transgenic mouse / 核内フォーカス / コバルト-60γ線 / Radiosensitivity / トリチウムガス / Environmental behavior / シャフロン / DNA依存性プロテインキナーゼ / 培養細胞 / スフェロプラスト融合法 / コメットアッセイ / Comet assay / Cancer prone disorder / DNA end-Joining / アポトーシス / トリチウムの生物影響 / YACコンティグ / mutation / Ku70 / 核融合炉 / 原子炉のトリチウム / Plag11 / M期チェックポイント / コメットアッセイ法 / 核融合 / DNA / Counting mechanism / 損傷乗り越えDNA複製 / Radiation / Transposition / β線 / カウンティング機構 / トリチウムガスの代謝生理学 / マウス / 突然変異誘発 / 動く遺伝子 / 放射線誘導タンパク / バイオドシメトリー / チェックポイント / Biological effects of tritium / 遺伝的組換え / Tritium / トリチウムの作用への移行 / 微小核移入法 / 非相同末端結合 / bio-dosimetry / Dandy-Walker奇形 / 温熱による放射線の増感 / DNA double strand break / biological effect / 異数性モザイク / BubRl / DNAヘリカーゼ / エピジェネティクス / Knockout mouse / 原子炉のトリチウム管理 / 遺伝疾患 / Neutron energy / Nbs 1 / Tritium gas / Ataxia telangiectasia遺伝子 / Neutron / Shaffron / 高発がん性遺伝病 / Tritiated water / Nuclear foci / radiation / Mobile genetic elements / 創始者ハプロタイプ / 染色体不安定症候群 / 連鎖解析候群 / Public Absorption dose / neutron / トリチウムの環境移行 / DNAの切断と再結合 / キネトコア / 環境動態 / p53欠失マウス / Embryonic lethal / Atm / グリオーマ幹細胞 / chromosome instability / リン酸化・脱リン酸化 / 遺伝子標的法 / 加速器 / RBE / apoptosis / Bloom syndrome / ヒストンH2AX / 転移 / neutron generator / Dose assessment / エネルギ-源 / エンドジョイニング / microinjection / カリフォルニウム-252中性子線 / 分裂期 / 高発癌性 / 遺伝子ホーミング / 果樹 / 遺伝子ノックアウト / 脳腫瘍学 / 胎生致死 / Wilms tumor / 紡錘体形成チェックポイント Less

Role of NBS1 C-terminal domain in genomic stabilityPrincipal Investigator
- Principal Investigator
  
  Komatsu Kenshi
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kyoto University
The experimental verification of saturated repair model by using repair reporter genes.Principal Investigator
- Principal Investigator
  
  Komatsu Kenshi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kyoto University
多重ドメイン蛋白によるユビキチンシグナルの選択性と疾患Principal Investigator
- Principal Investigator
  
  小松賢志
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Contribution of translesional DNA synthesis to UV-induced damage during embryogenesis and at low dose-rate.Principal Investigator
- Principal Investigator
  
  KOMATSU Kenshi
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kyoto University
Generation of ES cells to meseare DNA repair activity with reporter genes
- Principal Investigator
  
  KOBAYASHI Junya
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kyoto University
Roles of newly discovered NBS1 domains in ubiquitin signals and rejoining of double-strand breaks after irradiationPrincipal Investigator
- Principal Investigator
  
  KOMATSU Kenshi
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kyoto University
Molecular mechanism of radiation/NBS1-associated microcephalyPrincipal Investigator
- Principal Investigator
  
  KOMATSU Kenshi
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kyoto University
Functional analysis of Sox11 and Plagl1 in glioma stem cells.
- Principal Investigator
  
  KONDO Toru
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Hokkaido University
  Ehime University
グリオブラストーマ幹細胞のDNA修復能Principal Investigator
- Principal Investigator
  
  小松賢志
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kyoto University
Induction of DNA double strand break by environmental genotoxic and carcinogenic agentsPrincipal Investigator
- Principal Investigator
  
  KOMATSU Kenshi
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kyoto University
FUNCTIONAL ANALYSIS OF CANCER-SUSCEPTIBIE GENE, NBS1Principal Investigator
- Principal Investigator
  
  KOMATSU Kenshi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Origin of radiation-induced genomic instabilityPrincipal Investigator
- Principal Investigator
  
  KOMATSU Kenshi
- Project Period (FY)
  2002 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Kyoto University
Molecular cloning of the gene for cancer-prone syndrome characterized by abnormal mitotic spindle checkpoint.
- Principal Investigator
  
  MATSUURA Shinya
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human genetics
- Research Institution
  HIROSHIMA UNIVERSITY
DNA double strand break repair by NBS1 complex.
- Principal Investigator
  
  MATSUURA Shinya
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hiroshima University
Environmental behaviour of tritium and assessment of public absorption dose tritium
- Principal Investigator
  
  ICHIMASA Yusuke
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Nuclear fusion studies
- Research Institution
  Ibaraki University
Cancersusceptibility disease Nijmegen Breakage Syndrome and the function of underlying gene.Principal Investigator
- Principal Investigator
  
  KOMATSU Kenshi
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  KYOTO UNIVERSITY
  Hiroshima University
Mechanisms of cell responses by low dose and low dose-rate irradiation
- Principal Investigator
  
  OHNISHI Takeo
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Nara Medical University
Development of molecular bio-dosimeiry and monitor mice for the detection of radiation dose exposed by tritium water
- Principal Investigator
  
  KAMIYA Kenji
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nuclear fusion studies
- Research Institution
  HIROSHIMA UNIVERSITY
Molecular mechanism for chromosome stability using Nbs1 knockout mice
- Principal Investigator
  
  MATSUURA Shinya
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  HIROSHIMA UNIVERSITY
Role of NBS1 in Repair of DNA damage Induced by Ionizing Radiation
- Principal Investigator
  
  TAUCHI Hiroshi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  IBARAKI UNIVERSITY
  Hiroshima University
放射線感受性予測の基礎研究
- Principal Investigator
  
  鈴木紀夫
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
Generation of knockout mice for Nijmegen breakage syndrome gene, NBS1.
- Principal Investigator
  
  MATSUURA Shinya
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Hiroshima University
Tritium behavior in the environment and absorption dose
- Principal Investigator
  
  ICHIMASA Yusuke
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Nuclear fusion studies
- Research Institution
  IBARAKI UNIVERSITY
染色体8q21上の放射線誘発DNA二重鎖切断からの修復遺伝子のクローニングPrincipal Investigator
- Principal Investigator
  
  小松賢志
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Hiroshima University
Study on underlying gene of Nijmegen Breakage SyndromePrincipal Investigator
- Principal Investigator
  
  KOMATSU Kenshi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  HIROSHIMA UNIVERSITY
Novel developments on genetic recombination : DNA double-strand break and DNA end-joining
- Principal Investigator
  
  OHTSUBO Eichi, 池田日出男
- Project Period (FY)
  1998 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
  Kitasato Institute
Complementation assisted positional cloning of the gene for AT variant.
- Principal Investigator
  
  MATSUURA Shinya
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  Hiroshima University
高発癌遺伝病ナイミ-ヘン染色体不安定症候群の原因遺伝子の単離
- Principal Investigator
  
  MATSUURA Shinya
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hiroshima University
Development of (a human X-chromosome * hamster) hybrid cell assay system, which is sensitive to tritium exposure.Principal Investigator
- Principal Investigator
  
  KOMATSU Kenshi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nuclear fusion studies
- Research Institution
  HIROSHIMA UNIVERSITY
Studies on energy dependency of biological effects of neutrons and risk estimation
- Principal Investigator
  
  KUBOTA Nobuo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Ibaraki Prefectural University of Health Sciences
放射線感受性予測の基礎研究
- Principal Investigator
  
  鈴木紀夫
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Molecular study on Nijmegen breakage sybdromePrincipal Investigator
- Principal Investigator
  
  KOMATSU Kenshi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  HIROSHIMA UNIVERSITY
Multi-functions of DNA-dependent protein kinase (DNA-PK) and the association of radiation sensitivityPrincipal Investigator
- Principal Investigator
  
  KOMATSU Kenshi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  HIROSHIMA UNIVERSITY
Molecular mechanism of initiation of X inactivation using Xist YAC transgenic mouse
- Principal Investigator
  
  MATSUURA Shinya
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  HIROSHIMA UNIVERSITY
免疫不全症およびDNA修復欠損の原因遺伝子HYRCの特性と単離Principal Investigator
- Principal Investigator
  
  小松賢志
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hiroshima University
Research and development of transgenic mouse for biological effect assesment of tritiumPrincipal Investigator
- Principal Investigator
  
  KOMATSU Kenshi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nuclear fusion studies
- Research Institution
  HIROSHIMA UNIVERSITY
Development of a method of neutron spectrum measurement for monoenergetic neutrons generated from an accelerator for the use of radiation biology
- Principal Investigator
  
  HOSHI Masaharu
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  HIROSHIMA UNIVERSITY
免疫不全症およびDNA修復欠損の原因遺伝子HYRCの特性と単離Principal Investigator
- Principal Investigator
  
  小松賢志
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hiroshima University
Study on biological effectiveness of organic bound tritium by using DNA deficient cells.Principal Investigator
- Principal Investigator
  
  KOMATSU Kenshi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Nuclear fusion studies
- Research Institution
  HIROSHIMA UNIVERSITY
V(D)Jリコンビネース欠損突然変異を用いたDNA修復機序の解析Principal Investigator
- Principal Investigator
  
  小松賢志
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Nagasaki University
DNA修復能力と毛細血管拡張性運動失調症(AT)形質発現の解析Principal Investigator
- Principal Investigator
  
  小松賢志
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Nagasaki University
生体に与える低濃度トリチウムの長期被曝実験の検討
- Principal Investigator
  
  澤田昭三
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  放射線5生物学
- Research Institution
  Hiroshima University
The Mechanism of Hyper-radiosensitivity Expressed in Ataxia telangiectasia Disease.Principal Investigator
- Principal Investigator
  
  KOMATSU Kenshi
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  放射線5生物学
- Research Institution
  Nagasaki University School of Medicine
実験発がん系におけるトリチウム水のRBE
- Principal Investigator
  
  二階堂修
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Fusion Research
- Research Institution
  Kanazawa University
Modulating Effect of Protein Kinase C Activator on Radiation-Induced TransformationPrincipal Investigator
- Principal Investigator
  
  KOMATSU Kenshi
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  放射線5生物学
- Research Institution
  Nagasaki University

[Book] 現代人のための放射線生物学2017
- Author(s)
  小松賢志
- Total Pages
  342
- Publisher
  京都大学学術出版会
- Data Source
  KAKENHI-PROJECT-26241013
[Book] Nijmegen Breakage Syndrome (ナイミーヘン症候群)2015
- Author(s)
  加藤晃弘、柳原啓見、小松賢志
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-26241013
[Book] Nijmegen breakage syndrome(ナイミーヘン症候群)、「家族性腫瘍学」2015
- Author(s)
  加藤晃弘、柳原啓見、小松賢志
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-26550025
[Book] Nijmegen breakage syndrome(ナイミーヘン症候群)、「家族性腫瘍学」2015
- Author(s)
  加藤晃弘、柳原啓見、小松賢志
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-26241013
[Book] Nijmegen Breakage Syndrome (ナイミーヘン症候群)2015
- Author(s)
  加藤晃弘、柳原啓見、小松賢志
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PUBLICLY-25112513
[Book] Nijmegen Breakage Syndrome (ナイミーヘン症候群)2014
- Author(s)
  加藤晃弘、柳原啓見、小松賢志
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-26550025
[Book] DNA修復とゲノム不安定性2011
- Author(s)
  小松賢志
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23651045
[Book] DNA修復とゲノム不安定性2011
- Author(s)
  小松賢志
- Publisher
  がん生物学イラストレイテッド、羊土社
- Data Source
  KAKENHI-PROJECT-23651045
[Book] DNA修復とゲノム不安定性2011
- Author(s)
  小松賢志
- Publisher
  がん生物学イラストレイテッド、羊土社
- Data Source
  KAKENHI-PROJECT-23241021
[Book] Multiple roles of NBS1 for genotoxic and non-genotoxic stresses、Radiation Health Risk Science.2009
- Author(s)
  Komatsu K, Nakamura K, Yanagihara Hi, Kobayashi. Shimada M, Tsuchida K
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-17013040
[Book] NBS1 and MRE11 associate for regulation of checkpoints and for homologous recombination repair. International Congress Series 12992007
- Author(s)
  K. Komatsu, A. Antoccia, S. Sakamoto, J. Kobayashi, S. Matsuura, H. Tauchi. Human
- Publisher
  ELSEVIER
- Data Source
  KAKENHI-PROJECT-17013040
[Book] Radiation Health Risk Sciences2007
- Author(s)
  Kenshi Komatsu
- Total Pages
  340
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-18101002
[Book] Genome and Disease, Nijmegen breakage syndrome and functions of the responsible protein, NBS12006
- Author(s)
  A.Antoccia, J, Kobayashi, H.Tauchi, S.Matsuura, K.Komatsu
- Total Pages
  246
- Publisher
  Kerger (Basel)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14208068
[Book] 医学のあゆみ : Nijmegen 染色体不安定症候群と発がん2004
- Author(s)
  坂本修一, 小松賢志
- Total Pages
  898
- Publisher
  医歯薬出版株式会社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14208068
[Book] 血液・腫瘍科 : ゲノム修復とがん2004
- Author(s)
  大羽玲子, 小松賢志
- Total Pages
  242
- Publisher
  科学評論社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14208068
[Book] DNA複製・修復がわかる2004
- Author(s)
  槌田謙, 小松賢志
- Total Pages
  133
- Publisher
  ファンコニー貧血と染色体不安定性
- Data Source
  KAKENHI-PROJECT-12213087
[Book] DNA複製・修復がわかる2004
- Author(s)
  槌田謙, 小松賢志
- Total Pages
  133
- Data Source
  KAKENHI-PROJECT-14208068
[Book] DNA 複製・修復がわかる;ファンコニー貧血と染色体不安定性2004
- Author(s)
  槌田謙, 小松賢志
- Total Pages
  133
- Publisher
  羊土社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14208068
[Book] 遺伝子医学 : DNA 二重鎖切断によって生じるヒストンH2AXのリン酸化2003
- Author(s)
  中村麻子, 小松賢志
- Total Pages
  170
- Publisher
  株式会社メディカルドゥ
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14208068
[Book] 遺伝子医学 : ファンコニー貧血2002
- Author(s)
  白石貴博, 小松賢志
- Total Pages
  182
- Publisher
  株式会社メディカルドゥ
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14208068
[Journal Article] A comparison of radiation-induced mitochondrial damage between neural progenitor stem cells and differentiated cells.2017
- Author(s)
  Shimura T, Sasatani M, Kawai H, Kamiya K, Kobayashi J, Komatsu K, Kunugita N.
- Journal Title
  
  Cell Cycle
  
  Volume : 16 Pages : 565-573
- DOI
  10.1080/15384101.2017.1284716
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26241013, KAKENHI-PROJECT-15H02819, KAKENHI-PROJECT-15K12220, KAKENHI-PROJECT-16K00547
[Journal Article] ATM-mediated mitochondrial damage response triggered by nuclear DNA damage in normal human lung fibroblasts2017
- Author(s)
  Shimura T, Sasatani M, Kawai H, Kamiya K, Kobayashi J, Komatsu K, Kunugita N.
- Journal Title
  
  Cell cycle
  
  Volume : 16(24) Pages : 2345-2354
- DOI
  10.1080/15384101.2017.1387697
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K00547, KAKENHI-PROJECT-17K00553, KAKENHI-PROJECT-17K19944, KAKENHI-PROJECT-26241013, KAKENHI-PROJECT-15H02819, KAKENHI-PROJECT-17H06284
[Journal Article] Induction of somatic mutations by low-dose X-rays: the challenge in recognizing radiation-induced events2017
- Author(s)
  Nagashima Haruki、Shiraishi Kumiko、Ohkawa Saori、Sakamoto Yuki、Komatsu Kenshi、Matsuura Shinya、Tachibana Akira、Tauchi Hiroshi
- Journal Title
  
  Journal of Radiation Research
  
  Volume : 58 Pages : 1-7
- DOI
  10.1093/jrr/rrx053
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26241013, KAKENHI-PROJECT-15H04321
[Journal Article] Induction of Excess Centrosomes in Neural Progenitor Cells during the Development of Radiation-Induced Microcephaly.2016
- Author(s)
  Shimada M, Matsuzaki F, Kato A, Kobayashi J, Matsumoto T, Komatsu K.
- Journal Title
  
  PLoS One
  
  Volume : 11 Issue : 7
- Publisher
  Public Library of Science (PLoS)
- DOI
  10.1371/journal.pone.0158236
- ISSN
  1932-6203
- Year and Date
  2016-07-01
- Language
  English
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26241013, KAKENHI-PROJECT-15H02819
[Journal Article] Severe mitochondrial damage associated with low-dose radiation sensitivity in ATM- and NBS1-deficient cells.2016
- Author(s)
  Shimura T, Kobayashi J, Komatsu K, Kunugita N.
- Journal Title
  
  Cell Cycle
  
  Volume : 15 Pages : 1099-1107
- DOI
  10.1080/15384101.2016.1156276
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K12220, KAKENHI-PROJECT-26241013, KAKENHI-PROJECT-15H02819
[Journal Article] NBS1 and multiple regulations of DNA damage response.2016
- Author(s)
  Komatsu K.
- Journal Title
  
  J Radiat Res
  
  Volume : 57 Issue : S1 Pages : i11-i17
- Publisher
  Oxford University Press
- DOI
  10.1093/jrr/rrw031
- ISSN
  1349-9157
- Year and Date
  2016-08-16
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26241013
[Journal Article] Increased oxidative stress in AOA3 cells disturbs ATM-dependent DNA damage responses2015
- Author(s)
  Junya Kobayashi, Yuichiro Saito, Michiyo Okui, Noriko Miwa, Kenshi Komatsu
- Journal Title
  
  Mutation Research - Genetic Toxicology and Environmental Mutagenesis
  
  Volume : 未定
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26241013
[Journal Article] Increased oxidative stress in AOA3 cells disturbs ATM-dependent DNA damage responses2015
- Author(s)
  Junya Kobayashi, Yuichiro Saito, Michiyo Okui, Noriko Miwa, Kenshi Komatsu.
- Journal Title
  
  Mutation Research - Genetic Toxicology and Environmental Mutagenesis
  
  Volume : 未定
- Acknowledgement Compliant / Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26550025
[Journal Article] BRCA1 and CtIP are Both Required to Recruit Dna2 at Double-Strand Breaks in Homologous Recombination2015
- Author(s)
  Hoa NN., Kobayashi J., Omura M., Hirakawa M., Yang SH., Komatsu K., Paull TT., Takeda S., Sasanuma H
- Journal Title
  
  PLOS ONE
  
  Volume : 未定
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26241013
[Journal Article] Increased oxidative stress in AOA3 cells disturbs ATM-dependent DNA damage responses2015
- Author(s)
  Kobayashi J, et al.
- Journal Title
  
  Mutat Res Genet Toxicol Environ Mutagen
  
  Volume : 782 Pages : 42-50
- Publisher
  Elsevier B.V.
- DOI
  10.1016/j.mrgentox.2015.03.012
- PMID
  25868131
- ISSN
  1879-3592
- Language
  English
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24310041, KAKENHI-PROJECT-26241013, KAKENHI-PROJECT-15H02819, KAKENHI-PROJECT-26550025
[Journal Article] Increased oxidative stress in AOA3 cells disturbs ATM-dependent DNA damage responses.2015
- Author(s)
  Junya Kobayashi, Yuichiro Saito, Michiyo Okui, Noriko Miwa, Kenshi Komatsu
- Journal Title
  
  Mutation Research - Genetic Toxicology and Environmental Mutagenesis
  
  Volume : 未定
- Acknowledgement Compliant / Open Access / Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25112513
[Journal Article] Wilms' tumor gene WT1 promotes homologous recombination-mediated DNA damage repair.2015
- Author(s)
  Oji Y, Kobayashi J, et al.
- Journal Title
  
  Mol carcinog
  
  Volume : in press Pages : 1758-71
- DOI
  10.1002/mc.22248
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24310041, KAKENHI-PUBLICLY-25112513, KAKENHI-PROJECT-25460685, KAKENHI-PROJECT-26241013, KAKENHI-PROJECT-15K09476, KAKENHI-PROJECT-24510063, KAKENHI-PROJECT-24591395, KAKENHI-PROJECT-26550025
[Journal Article] Relative contribution of four nucleases, CtIP, Dna2, Exo1 and Mre11, to the initial step of DNA double-strand break repair by homologous recombination in both the chicken DT40 and human TK6 cell lines.2015
- Author(s)
  Hoa NN, Akagawa R, Yamasaki T, Hirota K, Sasa K, Natsume T, Kobayashi J, Sakuma T, Yamamoto T, Komatsu K, Kanemaki MT, Pommier Y, Takeda S, Sasanuma H
- Journal Title
  
  Genes Cells
  
  Volume : 20 Pages : 1059-1076
- DOI
  10.1111/gtc.12310
- Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K18482, KAKENHI-PUBLICLY-26116518, KAKENHI-PROJECT-23221005, KAKENHI-PROJECT-26550025, KAKENHI-PROJECT-25281021
[Journal Article] BRCA1 and CtIP are both required to recruit dna2 at double-strand breaks in homologous recombination.2015
- Author(s)
  Hoa NN, Kobayashi J, Omura M, Hirakawa M, Yang SH, Komatsu K, Paull TT, Takeda S, Sasanuma H.
- Journal Title
  
  PLoS One
  
  Volume : 10 Issue : 4
- Publisher
  Public Library of Science
- DOI
  10.1371/journal.pone.0124495
- PMID
  25909997
- ISSN
  1932-6203
- Year and Date
  2015-04-24
- Language
  English
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23221005, KAKENHI-PROJECT-26241013, KAKENHI-PROJECT-15H02819, KAKENHI-PROJECT-26550025
[Journal Article] BRCA1 and CtIP are Both Required to Recruit Dna2 at Double-Strand Breaks in Homologous Recombination2015
- Author(s)
  Hoa NN., Kobayashi J., Omura M., Hirakawa M., Yang SH., Komatsu K., Paull TT., Takeda S., Sasanuma H
- Journal Title
  
  PLOS ONE,
  
  Volume : 未定
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26550025
[Journal Article] Functional role of NBS1 in radiation damage response and translesion DNA synthesis.2015
- Author(s)
  Saito Y, Komatsu K.
- Journal Title
  
  Biomolecules.
  
  Volume : 5 Issue : 3 Pages : 1990-2002
- Publisher
  MDPI AG
- DOI
  10.3390/biom5031990
- PMID
  26308066
- ISSN
  2218-273X
- Year and Date
  2015-08-20
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26241013, KAKENHI-PROJECT-26550025
[Journal Article] BRCA1 and CtIP are Both Required to Recruit Dna2 at Double-Strand Breaks in Homologous Recombination2015
- Author(s)
  Hoa NN., Kobayashi J., Omura M., Hirakawa M., Yang SH., Komatsu K., Paull TT., Takeda S., Sasanuma H
- Journal Title
  
  PLOS ONE
  
  Volume : 未定
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25112513
[Journal Article] RNF20-SNF2H pathway of chromatin relaxation in DNA double-strand break repair2015
- Author(s)
  Akihiro Kato, Kenshi Komatsu
- Journal Title
  
  Genes
  
  Volume : 6 Issue : 3 Pages : 592-606
- Publisher
  MDPI
- DOI
  10.3390/genes6030592
- PMID
  26184323
- ISSN
  2073-4425
- Year and Date
  2015-07-14
- Language
  English
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K00536, KAKENHI-PROJECT-26241013, KAKENHI-PROJECT-26550025
[Journal Article] The proteasome factor Bag101 binds to Rad22 and suppresses homologous recombination.2014
- Author(s)
  Saito Y, Kobayashi J, et al.
- Journal Title
  
  Sci Rep.
  
  Volume : 3 Pages : 178-189
- DOI
  10.1038/srep02022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25550026, KAKENHI-PROJECT-23221005, KAKENHI-PROJECT-23241021, KAKENHI-PUBLICLY-24114509, KAKENHI-PUBLICLY-25112513, KAKENHI-PROJECT-25281021, KAKENHI-PROJECT-25550025
[Journal Article] Hypergonadotropic Hypogonadism and Hypersegmented Neutrophils in a Patient with Ataxia-Telangiectasia-Like Disorder: Potential Diagnostic Clues?2014
- Author(s)
  Yoshida T, Awaya T, Shibata M, Kato T, Numabe H, Kobayashi K, Komatsu K, Heike T
- Journal Title
  
  Am J Med Genet A
  
  Volume : 164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241021
[Journal Article] Mutations in the FHA-domain of ectopically expressed NBS1 lead to radiosensitization and to no increase in somatic mutation rates via a partial suppression of homologous recombination2014
- Author(s)
  Maki Ohara, Yumi Funyu, Shunsuke Ebara, Yuki Sakamoto, Ryota Seki, Kenta Iijima, Akiko Ohishi, Junya Kobayashi, Kenshi Komatsu, Akira Tachibana, and Hiroshi Tauchi
- Journal Title
  
  Journal of Radiation Research
  
  Volume : 55 Pages : 690-698
- DOI
  10.1093/jrr/rru011
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241021, KAKENHI-PROJECT-24310038, KAKENHI-PROJECT-24510064, KAKENHI-PUBLICLY-25112513, KAKENHI-PROJECT-25220102, KAKENHI-PROJECT-25550023, KAKENHI-PROJECT-25550026, KAKENHI-PROJECT-26241013, KAKENHI-PROJECT-26550025
[Journal Article] Mutations in the FHA-domain of ectopically expressed NBS1 lead to Radiosensitization and to no increase in somatic mutation rates via a partial suppression of homologous recombination2014
- Author(s)
  Maki Ohara, Yumi Funyu, Shunsuke Ebara, Yuki Sakamoto, Ryota Seki, Kenta Iijima, Akiko Ohishi, Junya Kobayashi, Kenshi Komatsu, Akira Tachibana, and Hiroshi Tauchi
- Journal Title
  
  J. Radiat. Res
  
  Volume : (in press)
- URL
  http://jrr.oxfordjournals.org/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25550025
[Journal Article] Hypergonadotropic Hypogonadism and Hypersegmented Neutrophils in a Patient with Ataxia-Telangiectasia-Like Disorder: Potential Diagnostic Clues?2014
- Author(s)
  Yoshida T, Awaya T, Shibata M, Kato T, Numabe H, Kobayashi K, Komatsu K, Heike T
- Journal Title
  
  Am J Med Genet
  
  Volume : 164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25550025
[Journal Article] ATM regulates Cdt1 stability during the unperturbed S phase to prevent re-replication2014
- Author(s)
  Iwahori S, Kohmon D, Kobayashi J, Tani Y, Yugawa T, Komatsu K, Kiyono T, Sugimoto N, Fujita M.
- Journal Title
  
  Cell cycle
  
  Volume : 13 Pages : 471-481
- DOI
  10.4161/cc.27274
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241021, KAKENHI-PROJECT-23590375, KAKENHI-PROJECT-24310041, KAKENHI-PROJECT-24650622, KAKENHI-PUBLICLY-25112513, KAKENHI-PROJECT-25291027, KAKENHI-PROJECT-25550025, KAKENHI-PROJECT-25870509, KAKENHI-PUBLICLY-26114713, KAKENHI-PROJECT-26550025
[Journal Article] ATM regulates Cdt1 stability during the unperturbed S phase to prevent re-replication.2014
- Author(s)
  Iwahori S, Kohmon D, Kobayashi J, Tani Y, Yugawa T, Komatsu K, Kiyono T, Sugimoto N, Fujita M.
- Journal Title
  
  Cell Cycle
  
  Volume : 13 Pages : 471-481
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26241013
[Journal Article] Histone chaperone FACT regulates homologous recombination by chromatin remodeling through interaction with RNF202014
- Author(s)
  Oliveira DV, Kato A, Nakamura K, Ikura T, Okada M, Kobayashi J, Yanagihara H, Saito Y, Tauchi H, Komatsu K
- Journal Title
  
  J Cell Sci,
  
  Volume : 127 Pages : 763-772
- DOI
  10.1242/jcs.135855
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22131001, KAKENHI-PROJECT-23241021, KAKENHI-PROJECT-24310038, KAKENHI-PROJECT-24510070, KAKENHI-PUBLICLY-25112513, KAKENHI-PROJECT-25550025, KAKENHI-PROJECT-25550026, KAKENHI-PROJECT-26241013, KAKENHI-PROJECT-26550025, KAKENHI-PLANNED-22131004, KAKENHI-PROJECT-23510061
[Journal Article] Hypergonadotropic Hypogonadism and Hypersegmented Neutrophils in a Patient with Ataxia-Telangiectasia-Like Disorder: Potential Diagnostic Clues?2014
- Author(s)
  Yoshida T, Kobayashi J, et al.
- Journal Title
  
  Am J Med Genet A
  
  Volume : 164 Issue : 7 Pages : 1830-1834
- Publisher
  Wiley
- DOI
  10.1002/ajmg.a.36546
- PMID
  24733832
- ISSN
  1552-4825
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24310041, KAKENHI-PUBLICLY-25112513, KAKENHI-PROJECT-25550025, KAKENHI-PROJECT-26241013, KAKENHI-PROJECT-26550025
[Journal Article] DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking.2013
- Author(s)
  Takeshi Kondo, Junya Kobayashi, Tatusya Saitoh, Kenta Maruyama. Ken J. Ishii, Glen N. Barber, Kenshi、Komatsu, Shizuo Akira, and Taro Kawai
- Journal Title
  
  Proc natl Acad Sci U S A
  
  Volume : 110 Pages : 2969-2974
- DOI
  10.1073/pnas.1222694110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J00081, KAKENHI-PROJECT-20002008, KAKENHI-PROJECT-23241021, KAKENHI-PROJECT-23689030, KAKENHI-PROJECT-24310041, KAKENHI-PROJECT-25550025
[Journal Article] The proteasome factor Bag101 binds to Rad22 and suppresses homologous recombination2013
- Author(s)
  Saito Y, Takeda J, Okada M, Kobayashi J, Kato A, Hirota K, Taoka M, Matsumoto T, Komatsu K, Isobe T
- Journal Title
  
  Sci Rep
  
  Volume : 3 Pages : 2022-2022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25550025
[Journal Article] High LET radiation amplifies centrosome overduplication through a pathway of γ-tubulin monoubiquitination2013
- Author(s)
  Shimada M, Hirayama R, Komatsu K.
- Journal Title
  
  International Journal of Radiation Oncology,Biology,Physics
  
  Volume : 86 Issue : 2 Pages : 358-365
- Publisher
  Elsevier Inc.
- DOI
  10.1016/j.ijrobp.2013.01.010
- PMID
  23433796
- ISSN
  0360-3016
- Year and Date
  2013-06-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241021, KAKENHI-PUBLICLY-25112513, KAKENHI-PROJECT-25550025
[Journal Article] 放射線によるDNA損傷の応答機構2012
- Author(s)
  小松賢志
- Journal Title
  
  バイオクリニカ、北隆館
  
  Volume : 27 Pages : 428-432
- Data Source
  KAKENHI-PROJECT-23651045
[Journal Article] 放射線リスクと生物研究2012
- Author(s)
  小松賢志
- Journal Title
  
  京都大学人環フォーラム
  
  Volume : 30 Pages : 10-13
- Data Source
  KAKENHI-PROJECT-23651045
[Journal Article] Genistein, isoflavonoids in soybeans, prevents the formation of excess radiation-induced centrosomes via p21 up-regulation2011
- Author(s)
  Shimada M, Kato A, Habu T, Komatsu K
- Journal Title
  
  Mutation Research
  
  Volume : Volume 716 Pages : 27-32
- DOI
  10.1016/j.mrfmmm.2011.07.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710053, KAKENHI-PROJECT-22710054, KAKENHI-PROJECT-23241021, KAKENHI-PROJECT-23501267, KAKENHI-PROJECT-23651045
[Journal Article] レントゲン以前の放射線修復遺伝子の役割は?2011
- Author(s)
  小松賢志
- Journal Title
  
  RIニュース
  
  Volume : 55 Pages : 2-3
- Data Source
  KAKENHI-PROJECT-23651045
[Journal Article] Regulation of homologous recombination by RNF20-dependent H2B ubiquitination2011
- Author(s)
  K.Nakamura, A.Kato, J.Kobayashi, H.Yanagihara, S.Sakamoto, D.V.N.P.Oliveira, M.Shimada, H.Tauchi, H.Suzuki, S.Tashiro, L.Zou, K.Komatsu.
- Journal Title
  
  Molecular Cell 41
  
  Pages : 515-628
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] NBS1 recruits RAD18 via aRAD6-like domain and regulates Polη-dependent translesion DNA synthesis2011
- Author(s)
  Yanagihara H, Kobayashi J, Tateishi S, Kato A, Matsuura S, Tauchi H, Yamada K, Takezawa J, Sugasawa K, Masutani C, Hanaoka F, Weemaes CM, Mori T, Zou L, Komatsu K.
- Journal Title
  
  Mol Cell
  
  Volume : 43 Issue : 5 Pages : 788-797
- Publisher
  Elsevier Ltd.
- DOI
  10.1016/j.molcel.2011.07.026
- PMID
  21884979
- ISSN
  1097-4164
- Year and Date
  2011-09-02
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310035, KAKENHI-PUBLICLY-22019026, KAKENHI-ORGANIZER-22131001, KAKENHI-PLANNED-22131008, KAKENHI-PROJECT-22651018, KAKENHI-PROJECT-22710053, KAKENHI-PROJECT-23241021, KAKENHI-PROJECT-23651045, KAKENHI-PROJECT-22249005
[Journal Article] Bisbenzamidine derivative, pentamidine represses DNA damage response through inhibition of histone H2A acetylation2010
- Author(s)
  K.Komatsu
- Journal Title
  
  Mol.Cancer
  
  Volume : 9 Pages : 34-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Differential role of repair proteins, BRCA1/NBS1 and Ku70/DNA-PKc in radiation-induced centrosome over-duplication2010
- Author(s)
  K.Komatsu
- Journal Title
  
  Cancer Sci
  
  Volume : 101 Pages : 2531-2537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Regulation of homologous recombination by RNF20-dependent H2B ubiquitination2010
- Author(s)
  K.Komatsu
- Journal Title
  
  Mol.Cell
  
  Volume : 41 Pages : 515-628
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Regulation of homologous recombination by RNF20-dependent H2B ubiquitination2010
- Author(s)
  K.Komatsu
- Journal Title
  
  Mol.Cell
  
  Volume : 41 Pages : 515-628
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651016
[Journal Article] Differential role of repair proteins, BRCA1/NBS1 and Ku70/DNA-PKcs, in radiation-induced centrosome over-duplication2010
- Author(s)
  M.Shimada, J.Kobayashi, R.Hirayama, K.Komatsu.
- Journal Title
  
  Cancer Sci. 101
  
  Pages : 2531-2537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Bisbenzamidine derivative, pentamidine represses DNA damage response through inhibition of histone H2A acetylation2010
- Author(s)
  K.Komatsu
- Journal Title
  
  Mol.Cancer
  
  Volume : 9 Pages : 34-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651016
[Journal Article] Bisbenzamidine derivative, Pentamidine represses DNA damage response through inhibition of histone H2A acetylation.2010
- Author(s)
  Kobayashi J, Kato A, Ota Y, Ohba R, Komatsu K.
- Journal Title
  
  Mol. Cancer 9
  
  Pages : 34-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013040
[Journal Article] Bisbenzamidine derivative, pentamidine represses DNA damage response through inhibition of histone H2A acetylation.2010
- Author(s)
  J.Kobayashi, A.Kato, Y.Ota, R.Ohba, K.Komatsu.
- Journal Title
  
  Mol.Cancer 9
  
  Pages : 34-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] WRN participates in translesion synthesis pathway through interaction with NBS1.2010
- Author(s)
  J.Kobayashi, M.Okui, A.Asaithamby, S.Burma, B.P.Chen, K.Tanimoto, S.Matsuura, K.Komatsu, D.J.Chen.
- Journal Title
  
  Mechanisms of Ageing and Development 131
  
  Pages : 436-444
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Differential role of repair proteins, BRCA1/NBS1 and Ku70/DNA-PKc in radiation-induced centrosome over-duplication2010
- Author(s)
  K.Komatsu
- Journal Title
  
  Cancer Sci
  
  Volume : 101 Pages : 2531-2537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651016
[Journal Article] Acquired radioresistance of human tumor cells by DNA-PK/AKT/GSK3 β-mediated cyclinD1 overexpression.2010
- Author(s)
  T.Shimura, S.Kakuda, Y.Ochiai, H.Nakagawa, Y.Kuwahara, Y.Takai, J.Kobayashi, K.Komatsu, M.Fukumoto.
- Journal Title
  
  Oncogene 29
  
  Pages : 4826-4837
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Emerging connection between centrosome and DNA repair machinery.2009
- Author(s)
  M.Shimada, K.Komatsu.
- Journal Title
  
  J Radiat Res. 50
  
  Pages : 295-301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Inactivation of the Nijmegen breakage syndrome gene NBS1 leads to excess centrosome duplication via the ATR/BRCA1 pathway.2009
- Author(s)
  Shimada M, Sagae R, Kobayashi J, Habu T, Komatsu K.
- Journal Title
  
  Cancer Research 69
  
  Pages : 1768-1775
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Inactivation of the Nijmegen breakage syndrome gene NBS1 leads to excess centrosome duplication via the ATR/BRCA1 pathway2009
- Author(s)
  Komatsu K
- Journal Title
  
  Cancer Research 69
  
  Pages : 1768-1775
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Histone H2AX participates the DNA damage-induced ATM activation through interaction with NBS1.2009
- Author(s)
  Kobayashi J, Tauchi H, Chen B, Bruma S, Tashiro S, Matsuura S, Tanimoto K, Chen DJ, Komatsu K.
- Journal Title
  
  Biochem Biophys Res Commun. 380
  
  Pages : 752-757
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013040
[Journal Article] Inactivation of the Nijmegen breakage syndrome gene NBS1 leads to excess centrosome duplication via the ATR/BRCA1 pathway2009
- Author(s)
  Komatsu K
- Journal Title
  
  Cancer Research 69
  
  Pages : 1768-1775
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013040
[Journal Article] Histone H2AX participates the DNA damage-induced ATM activation through interaction with NBS12009
- Author(s)
  Komatsu K
- Journal Title
  
  Biochem Biophys Res Commun. 380
  
  Pages : 752-757
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Emerging connection between centrosome and DNA Emerging repair machinery.2009
- Author(s)
  Shimada M, Komatsu K.
- Journal Title
  
  J Radiat Res 50
  
  Pages : 295-301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013040
[Journal Article] Two major factors involved in the reverse dose-rate effect for somatic mutation induction are the cell cycle position and LET value.2009
- Author(s)
  Tauchi H, Waku H, Matsumoto E, Yara S, Okumura S, Iwata Y, Komatsu K, Furusawa Y, Eguchi-Kasai K, Tachibana A.
- Journal Title
  
  J Radiat Res 50
  
  Pages : 441-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013040
[Journal Article] Inactivation of the Nijmegen breakage syndrome gene NBS1 leads to excess centrosome duplication via the ATR/BRCA1 pathway2009
- Author(s)
  Shimada M, Sagae R, Kobayashi J, Habu T, Komatsu K,K.
- Journal Title
  
  Cancer Research 69
  
  Pages : 1768-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Histone H2AX participates the DNA damage-induced ATM activation through interaction with NBS1.2009
- Author(s)
  Kobayashi J, Tauchi H, Chen B, Bruma S, Tashiro S, Matsuura S, Tanimoto K, Chen DJ, Komatsu K.
- Journal Title
  
  Biochem Biophys Res Commun. 380
  
  Pages : 752-757
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Histone H2AX participates the DNA damage induced ATM activation through interaction with NBS12009
- Author(s)
  Komatsu K
- Journal Title
  
  Biochem Biophys Res Commun. 380
  
  Pages : 752-757
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013040
[Journal Article] Centrosome maintenance and genome instability.2009
- Author(s)
  Shimada M.Komatsu K.
- Journal Title
  
  J Radiat Res in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Inactivation of the Nijmegen breakage syndrome gene NBS1 leads to excess centrosome duplication via the ATR/BRCA1 pathway.2009
- Author(s)
  Shimada M, Sagae R, Kobayashi J, Habu T, Komatsu K.
- Journal Title
  
  Cancer Research 69
  
  Pages : 1768-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013040
[Journal Article] Histone H2AX participates the DNA damage-induced ATM activation through interaction with NBS12009
- Author(s)
  Kobayashi J, Tauchi H, Chen B, Bruma S, Tashiro S, Matsuura S, Tanimoto K, Chen DJ, Komatsu K
- Journal Title
  
  Biochem Biophys Res Commun. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Two major factors involved in the reverse dose-rate effect for somatic mutation induction are the cell cycle position and LET value.2009
- Author(s)
  H.Tauchi, H.Waku, E.Matsumoto, S.Yara, S.Okumura, Y.Iwata, K.Komatsu, Y.Furusawa, K.Eguchi-Kasai, A.Tachibana.
- Journal Title
  
  J Radiat Res. 50
  
  Pages : 441-448
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] DNA double strand break repair enzymes function at multiple steps in HIV-1 infection.2009
- Author(s)
  Sakurai, Y. Komatsu, K. Agematsu, K. Matsuoka, M.
- Journal Title
  
  Retrovirology. 6
  
  Pages : 114-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013040
[Journal Article] DNA double strand break repair enzymes function at multiple steps in HIV-1 infection.2009
- Author(s)
  Y.Sakurai, K.Komatsu, K.Agematsu, M.Matsuoka.
- Journal Title
  
  Retrovirology 6
  
  Pages : 114-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] NBS1 regulates a novel apoptotic pathway through Bax activation.2008
- Author(s)
  Iijima K, Muranaka C, Kobayashi J, Sakamoto S, Komatsu K, Matsuura S, Kubota N, Tauchi H.
- Journal Title
  
  DNA Repair 7
  
  Pages : 1705-1716
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] NBS1 prevents chromatid-type aberrations through ATM-dependent interactions with SMC1.2008
- Author(s)
  Antoccia A, Sakamoto S, Matsuura S, Tauchi H, Komatsu K.
- Journal Title
  
  Radiat Res. 170
  
  Pages : 345-352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013040
[Journal Article] Potential Link between Alternative Splicing of the NBS1 Gene and theDNA Damage/Environmental Stress.2008
- Author(s)
  Takai K, Sakamoto S, Sakai T, Yasunaga J, Komatsu K, Matsuoka M.
- Journal Title
  
  Radiat Res. 170
  
  Pages : 33-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013040
[Journal Article] NBS1 prevents chromatid-type aberrations through ATM-dependent interactions with SMC1.2008
- Author(s)
  Antoccia A, Sakamoto S, Matsuura S, Tauchi H, Komatsu K.
- Journal Title
  
  Radiat Res. 170
  
  Pages : 345-352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Impaired removal of DNA interstrand cross-link in Nijmegen breakage syndrome and Fanconi anemia, but not in BRCA-defective group.2008
- Author(s)
  Tsuchida K., Komatsu K.
- Journal Title
  
  Cancer Sci. 99
  
  Pages : 2238-2243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Potential Link between Alternative Splicing of the NBS1 Gene and the DNA Damage/Environmental Stress.2008
- Author(s)
  Takai K, Sakamoto S, Sakai T, Yasunaga J, Komatsu K, Matsuoka M.
- Journal Title
  
  Radiat Res. 170
  
  Pages : 33-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Impaired removal of DNA interstrand cross-link in Nijmegen breakage syndrome and Fanconi anemia, but not in BRCA-defective group.2008
- Author(s)
  Tsuchida K., Komatsu K.
- Journal Title
  
  Cancer Sci. 99
  
  Pages : 2238-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013040
[Journal Article] NBS1 prevents chromatid-type aberrations through ATM-dependent interactions with SMC12008
- Author(s)
  Antoccia A, Sakamoto S, Matsuura S, Tauchi H, Komatsu K
- Journal Title
  
  Radiat Res 170
  
  Pages : 345-352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Ono T. Absence of Ku70 gene obliterates X-ray-induced lacZ mutagenesis of small deletions in mouse tissues.2008
- Author(s)
  Uehara Y, Ikehata H, Komura J, Ito A, Ogata M, Itoh T, Hirayama R, Furusawa Y, Ando K, Paunesku T, Woloschak GE, Komatsu K, Matsuura S, Ikura T, Kamiya K
- Journal Title
  
  Radiat Res. 170
  
  Pages : 216-223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013040
[Journal Article] Absence of Ku70 gene obliterates X-ray-induced lacZ mutagenesis of small deletions in mouse tissues.2008
- Author(s)
  Uehara Y, Ikehata H, Komura J, Ito A, Ogata M, Itoh T, Hirayama R, Furusawa Y, Ando K, Paunesku T, Woloschak GE, Komatsu K, Matsuura S, Ikura T, Kamiya K, Ono T.
- Journal Title
  
  Radiat Res. 170
  
  Pages : 216-223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] NBS1 regulates a novel apoptotic pathway through Bax activation.2008
- Author(s)
  Iijima K, Muranaka C, Kobayashi J, Sakamoto S, Komatsu K, Matsuura S, Kubota N, Tauchi H.
- Journal Title
  
  DNA Repair 7
  
  Pages : 1705-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013040
[Journal Article] Human NBS1 NBS1 and MRE11 associate for regulation of checkpoints and for homologous recombination repair.2007
- Author(s)
  K.Komatsu
- Journal Title
  
  International Congress Series, ELSEVIER 1299
  
  Pages : 158-163
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Homologous recombination repair is regulated by domains at the C-terminus of NBS1 and is independent of ATM.2007
- Author(s)
  S. Sakamoto, K. Iijima, D. Mochizuki, K. Nakamura, K. Teshigawara, J. Kobayashi, S. Matsuura, H. Tauchi, K. Komatsu.
- Journal Title
  
  Oncogene 26
  
  Pages : 6002-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013040
[Journal Article] Homologous recombination repair is regulated by domains at the N- and C-terminus of NBS1 and is dissociated with ATM functions2007
- Author(s)
  Sakamoto S., Iijima K., Mochizuki D., Nakamura K., Teshigawara K., Kobayashi J., Matsuura S., Tauchi H., Komatsu K.
- Journal Title
  
  Oncogene 26
  
  Pages : 6002-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] TopBP1 associates with NBS1 and is involved in homologous recombination repair.2007
- Author(s)
  Morisima.K., Sakamoto.S., Kobayashi.J., Izumi.H., Suda.T., Matsumoto.Y., Tauchi.H., Ide.H., Komatsu K.Matsuura.S.
- Journal Title
  
  Biochem Biophys Res Commun. 362
  
  Pages : 872-879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Human NBS1 and MRE11 associate for regulation of checkpoints and for homologous recombination repair.2007
- Author(s)
  K.Komatsu
- Journal Title
  
  International Congress Series, ELSEVIER 1299
  
  Pages : 158-163
- Data Source
  KAKENHI-PROJECT-17013040
[Journal Article] Homologous recombination repair is regulated by domains at the N- and C-terminus of NBS1 and is dissociated with ATM functions.2007
- Author(s)
  Sakamoto.S., Iijima.K., Mochizuki.D., Nakamura.K., Teshigawara.K., Kobayashi.J., Matsuura.S., Tauchi.H.Komatsu K.
- Journal Title
  
  Oncogene. 26
  
  Pages : 6002-6009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Human NBS1 and MRE1 associate for regulation of checkpoints and for homologous recombination repair.2007
- Author(s)
  K. Komatsu
- Journal Title
  
  ELSEVIER 1299
  
  Pages : 158-163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Human NBS1 and MRE1 associate for regulation of checkpoints and for homologous recombination repair.2007
- Author(s)
  K. Komatsu
- Journal Title
  
  ELSEVIER 1299
  
  Pages : 158-163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013040
[Journal Article] Monoallelic BUB1B Mutations and Defective Mitotic-Spindle Checkpoint in Seven Families With Premature Chromatid Separation (PCS) Syndrome.2006
- Author(s)
  S.Matsuura, Y.Matsumoto, K.Morishima, H.Izumi, H.Matsumoto, E.Ito, K.Tsutsui, J.Kobayashi, H.Tauchi, Y.Kajiwara, S.Hama, K.Kurisu, H.Tahara, M.Oshimura, K.Komatsu, Tatsuro Ikeuchi, Tadashi Kajii.
- Journal Title
  
  Amer J Med Genet. 140(4)
  
  Pages : 358-367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] ATM Activation by a Sulfhydryl-Reactive Inflammatory Cyclopentenone Prostaglandin.2006
- Author(s)
  M.Kobayashi, H.Ono, K.Mihara, H.Tauchi, K.Komatsu, H.Shimizu, K.Uchida, K.Yamamoto.
- Journal Title
  
  Genes Cells 11(7)
  
  Pages : 779-789
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] DNA Repair Defect in AT Cells and their Hypersensitivity to Low-Dose-Rate Radiation.2006
- Author(s)
  H.Nakamura, Y.Yasui, N.Saito, A.Tachibana, K.Komatsu, K.Ishizaki.
- Journal Title
  
  Radiation research. 165
  
  Pages : 277-282
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Association of Ionizing Radiation-Induced Foci of NBS1 with Association of Ionizing Chromosomal Instability and Breast Cancer Susceptibility.2006
- Author(s)
  M. Someya, K. Sakata, H. Tauchi, Y. Matsumoto, A. Nakamura, K. Komatsu, M. Hareyama.
- Journal Title
  
  Radiation Research. 166
  
  Pages : 575-582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013040
[Journal Article] Nijmegen Breakage Syndrome and Functions of the Responsible Nijmegen Breakage Protein2006
- Author(s)
  A. Antoccia, J. Kobayashi, H. Tauchi, S. Matsuura, K. Komatsu.
- Journal Title
  
  NBS1. Genome Dyn. 1
  
  Pages : 191-205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013040
[Journal Article] Association of Ionizing Radiation-Induced Foci of NBS1 with Chromosomal Instability and Breast Cancer Susceptibility.2006
- Author(s)
  M.Someya, K.Sakata, H.Tauchi, Y.Matsumoto, A.Nakamura, K.Komatsu, M.Hareyama.
- Journal Title
  
  Radiation Research. 166
  
  Pages : 575-582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] DNA Repair Defect in AT Cells and their Ishizaki. Hypersensitivity to Low-Dose-Rate Radiation.2006
- Author(s)
  H. Nakamura, Y. Yasui, N. Saito, A. Tachibana, K. Komatsu, Ishizaki
- Journal Title
  
  Radiation research. 165
  
  Pages : 277-282
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013040
[Journal Article] Monoallelic BUB1B Mutations and Defective Mitotic-Spindle Checkpoint in Seven Families With Premature Chromatid Separation (PCS) Syndrome.2006
- Author(s)
  S. Matsuura, Y. Matsumoto, K. Morishima, H. Izumi, H. Matsumoto, E. Ito, K. Tsutsui, J. Kobayashi, H. Tauchi, Y. Kajiwara, S. Hama, K. Kurisu, H. Tahara, M. Oshimura, K. Komatsu, Tatsuro Ikeuchi, Tadashi Kajii.
- Journal Title
  
  Amer J Med Genet. 140(4)
  
  Pages : 358-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013040
[Journal Article] ATM Activation by a Sulfhydryl-Reactive Inflammatory Cyclopentenone Prostaglandin.2006
- Author(s)
  M. Kobayashi, H. Ono, K. Mihara, H. Tauchi, K. Komatsu, H. Shimizu, K. Uchida, K. Yamamoto.
- Journal Title
  
  Genes Cells 11(7)
  
  Pages : 779-789
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013040
[Journal Article] Nijmegen Breakage Syndrome and Functions of the Responsible Protein, NBS1.2006
- Author(s)
  Antoccia, J.Kobayashi, H.Tauchi, S.Matsuura, K.Komatsu.
- Journal Title
  
  Genome Dyn.Basel, Karger. 1
  
  Pages : 191-205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Ataxia-telangiectasia-mutated dependent phosphorylation of Artemis in response to DNA damage2005
- Author(s)
  Chen L, Morio T, Minegishi Y, Nakada S, Nagasawa M, Komatsu K, Chessa L, Villa A, Lecis D, Delia D, Mizutani S.
- Journal Title
  
  Cancer Science 96
  
  Pages : 134-141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013040
[Journal Article] Werner syndrome protein associates with gamma H2AX in a manner that depends upon NBS12005
- Author(s)
  Cheng W, Kobbe G, Opresko P L, Arthur L M, Komatsu K, Sidman M M, Carney J P, Bohr V A.
- Journal Title
  
  FEBS Letters 579(6)
  
  Pages : 1350-1356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013040
[Journal Article] Measurements of DNA Inter-crosslink and the repair time course.2005
- Author(s)
  Ken Tsuchida, Kenshi Komatsu
- Journal Title
  
  (Submitted) No.2005-207121
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208068
[Journal Article] Accumulation of Werner protein at DNA double-strand breaks in human cells2005
- Author(s)
  Li Lan, Satoshi Nakajima, Kenshi Komatsu, Andre Nussenzweig, Akira Shimamoto, Junko Oshima, Akira Yasui
- Journal Title
  
  J Cell Sci. 118
  
  Pages : 4153-4162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013040
[Journal Article] Fanconi Anemia protein FANCD2 promotes Thompson LH and Takata M. immunoglobulin gene conversion and DNA repair through a mechanism related to homologous recombination.2005
- Author(s)
  Yamamoto K, Hirano S, Ishiai M, Morishima K, Kitao H, Kimura M, Namikoshi K, Matsushita N, Arakawa H, Buerstedde JM, Komatsu K, Thompson LH, Takata M.
- Journal Title
  
  Mol. Cell. Biol. 25
  
  Pages : 34-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013040
[Journal Article] The Nijmegen breakage syndrome gene and its role in genome stability.2004
- Author(s)
  Iijima K, Komatsu K, et al.
- Journal Title
  
  Chromosoma 113
  
  Pages : 53-61
- Data Source
  KAKENHI-PROJECT-14208068
[Journal Article] The Nijmegen breakage syndrome gene and its role in genome stability.2004
- Author(s)
  Iijima K, Komatsu K, et al.
- Journal Title
  
  Chromosoma 113
  
  Pages : 53-61
- Data Source
  KAKENHI-PROJECT-12213087
[Journal Article] Centrosome maintenance and genome instability.
- Author(s)
  K. Komatsu
- Journal Title
  
  Radiation Research (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Presentation] 日本人AT-LD患者におけるMRE11変異部位とDNA損傷応答異常との関係2017
- Author(s)
  河村香寿、Qi Fei、加藤竹雄、松浦伸也、小松賢志、小林純也
- Organizer
  日本放射線影響学会第60回大会
- Data Source
  KAKENHI-PROJECT-26241013
[Presentation] NBS1 の新規 C 末端ドメインは NHEJ の亢進に関与する2017
- Author(s)
  加藤晃弘、柳原啓見、小松賢志
- Organizer
  第34回染色体ワークショップ・第15回核ダイナミクス研究会
- Place of Presentation
  木更津市
- Year and Date
  2017-01-11
- Data Source
  KAKENHI-PROJECT-26241013
[Presentation] Oxidative stress and DNA damage responses under low dose rate irradiation2016
- Author(s)
  Kobayashi J, Saito Y, Kato A, Oliveira DV, Yanagihara H, Matsuura S, Komatsu K.
- Organizer
  The 2nd KU RBC-CEA Joint Workshop
- Place of Presentation
  Kyoto.
- Year and Date
  2016-04-11
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-26241013
[Presentation] NBS1 controls homologous recombination and non-homologous end joining in different ways.2016
- Author(s)
  Akihiro Kato, Hiromi Yanagihara, and Kenshi Komatsu.
- Organizer
  The 10th International 3R Symposium
- Place of Presentation
  Matue
- Year and Date
  2016-04-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26241013
[Presentation] Dose-dependent regulation of two rejoining pathways for DNA double-strand breaks2015
- Author(s)
  Yuichiro Saito, Makoto Ihara, Akihiro Kato, Junya Kobayashi, Kenshi Komatsu
- Organizer
  30th RBC-NIRS International Symposium
- Place of Presentation
  京都
- Year and Date
  2015-02-20
- Invited
- Data Source
  KAKENHI-PUBLICLY-25112513
[Presentation] Functional analysis of the novel C-terminus domain of NBS1.2015
- Author(s)
  Kato A. Komatsu K
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26241013
[Presentation] Dose-dependent regulation of two rejoining pathways for DNA double-strand breaks2015
- Author(s)
  Saito Y, Ihara M, Hirayama R, Kobayashi J, Komatsu K
- Organizer
  15th International Congress of Radiation Research
- Place of Presentation
  Kyoto
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26550025
[Presentation] Regulation of various DNA damage responses through complex formations of NBS1.2015
- Author(s)
  Kobayashi J, Saito Y, Kato A, Oliveira DV, Yanagihara H, Matsuura S, Komatsu K.
- Organizer
  16th Ataxia-Telangiectasia Workshop
- Place of Presentation
  Beijing
- Year and Date
  2015-10-11
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-26550025
[Presentation] Roles of NBS1 in homologous recombination and translesional DNA synthesis.2015
- Author(s)
  Komatsu K
- Organizer
  RBC-CEA Workshop,
- Place of Presentation
  Fontenay-aux-Roses (France)
- Year and Date
  2015-04-08
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-26241013
[Presentation] NBS1物語2015
- Author(s)
  小松賢志
- Organizer
  日本放射線影響学会・放射線ワークショップ
- Place of Presentation
  富山
- Year and Date
  2015-10-16
- Invited
- Data Source
  KAKENHI-PROJECT-26550025
[Presentation] Dose-dependent regulation of two rejoining pathways for DNA double-strand breaks.2015
- Author(s)
  Yuichiro Saito, Makoto Ihara, Akihiro Kato, Junya Kobayashi, Kenshi Komatsu.
- Organizer
  30th RBC-NIRS International Symposium
- Place of Presentation
  京都
- Year and Date
  2015-02-20
- Invited
- Data Source
  KAKENHI-PROJECT-26241013
[Presentation] Dual Roles of NBS1 in translesion DNA synthesis and response to Radiation damage.2015
- Author(s)
  Komatsu K.
- Organizer
  Zing Conferece
- Place of Presentation
  Cairns (Australia)
- Year and Date
  2015-08-01
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-26241013
[Presentation] Cloning of NBS1 and repair genes2015
- Author(s)
  Komatsu K.
- Organizer
  15th International Congress of Radiation Research
- Place of Presentation
  Kyoto,
- Year and Date
  2015-05-25
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-26550025
[Presentation] NBS1物語2015
- Author(s)
  小松賢志
- Organizer
  日本放射線影響学会・放射線ワークショップ
- Place of Presentation
  富山
- Year and Date
  2015-10-16
- Invited
- Data Source
  KAKENHI-PROJECT-26241013
[Presentation] Cloning of NBS1 and repair genes2015
- Author(s)
  Komatsu K.
- Organizer
  15th International Congress of Radiation Research
- Place of Presentation
  Kyoto,
- Year and Date
  2015-05-25
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-26241013
[Presentation] Regulation of various DNA damage responses through complex formations of NBS1.2015
- Author(s)
  Kobayashi J, Saito Y, Kato A, Oliveira DV, Yanagihara H, Matsuura S, Komatsu K.
- Organizer
  16th Ataxia-Telangiectasia Workshop
- Place of Presentation
  Beijing
- Year and Date
  2015-10-11
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-26241013
[Presentation] Roles of NBS1 in homologous recombination and translesional DNA synthesis.2015
- Author(s)
  Komatsu K
- Organizer
  RBC-CEA Workshop
- Place of Presentation
  Fontenay-aux-Roses (France)
- Year and Date
  2015-04-08
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-26550025
[Presentation] Dose-dependent regulation of two rejoining pathways for DNA double-strand breaks.2015
- Author(s)
  Yuichiro Saito, Makoto Ihara, Akihiro Kato, Junya Kobayashi, Kenshi Komatsu
- Organizer
  30th RBC-NIRS International Symposium
- Place of Presentation
  京都
- Year and Date
  2015-02-20
- Invited
- Data Source
  KAKENHI-PROJECT-26550025
[Presentation] Dual Roles of NBS1 in translesion DNA synthesis and response to Radiation damage.2015
- Author(s)
  Komatsu K
- Organizer
  Zing Conferece
- Place of Presentation
  Cairns (Australia)
- Year and Date
  2015-08-01
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-26550025
[Presentation] Roles of NBS1 in radiation responses and initiation of translesional DNA synthesis2014
- Author(s)
  Kenshi Komatsu
- Organizer
  5th US-Japan DNA Repair
- Place of Presentation
  Naruto
- Year and Date
  2014-10-01
- Invited
- Data Source
  KAKENHI-PROJECT-26550025
[Presentation] NBS1蛋白C末側ドメインとDNA損傷応答における役割2014
- Author(s)
  小松賢志、加藤晃弘、柳原啓見、斎藤裕一朗、周慧、小林純也
- Organizer
  日本放射線影響学会
- Place of Presentation
  鹿児島
- Year and Date
  2014-10-01
- Invited
- Data Source
  KAKENHI-PROJECT-26550025
[Presentation] NBS1蛋白C末側ドメインとDNA損傷応答における役割2014
- Author(s)
  小松賢志、加藤晃弘、柳原啓見、斎藤裕一朗、周慧、小林純也
- Organizer
  日本放射線影響学会
- Place of Presentation
  鹿児島
- Year and Date
  2014-10-01
- Invited
- Data Source
  KAKENHI-PROJECT-26241013
[Presentation] 紫外線損傷乗り越えDNA合成と電離放射線の修復蛋白NBS12014
- Author(s)
  小松賢志
- Organizer
  光医学・光生物学会
- Place of Presentation
  大阪
- Year and Date
  2014-07-25
- Invited
- Data Source
  KAKENHI-PUBLICLY-25112513
[Presentation] 相同組換え修復と損傷乗越えDNA合成におけるNBS1蛋白の役割2014
- Author(s)
  小松賢志、加藤晃弘、柳原啓見、斎藤裕一朗、周慧、小林純也
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25
- Invited
- Data Source
  KAKENHI-PROJECT-26550025
[Presentation] NBS1 plays a role in UV damage response through physical interaction with RAD182014
- Author(s)
  A Kato, H Yanagihara, J Kobayashi, Y Saito, D Oliveira, C Weemaes, and K Komatsu
- Organizer
  International Symposium on Xeroderma Pigmentosum and Related Diseases: Disorders of DNA Damage Response
- Place of Presentation
  Kobe
- Invited
- Data Source
  KAKENHI-PROJECT-25550025
[Presentation] 放射線/制がん剤の細胞感受性におけるNBS1 の役割と阻害剤スクリーニング2014
- Author(s)
  小松賢志, 加藤晃弘
- Organizer
  第16回癌治療増感研究シンポジウム
- Place of Presentation
  奈良市
- Year and Date
  2014-02-08
- Invited
- Data Source
  KAKENHI-PROJECT-25550025
[Presentation] Roles of NBS1 in radiation responses and initiation of translesional DNA synthesis2014
- Author(s)
  Kenshi Komatsu.
- Organizer
  5th US-Japan DNA Repair
- Place of Presentation
  鳴門
- Year and Date
  2014-10-29
- Invited
- Data Source
  KAKENHI-PROJECT-26241013
[Presentation] 相同組換え修復と損傷乗越えDNA合成におけるNBS1蛋白の役割2014
- Author(s)
  小松賢志、加藤晃弘、柳原啓見、斎藤裕一朗、周慧、小林純也
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25
- Invited
- Data Source
  KAKENHI-PROJECT-26241013
[Presentation] 紫外線損傷乗り越えDNA合成と電離放射線の修復蛋白NBS12014
- Author(s)
  小松賢志
- Organizer
  光医学・光生物学会
- Place of Presentation
  大阪
- Year and Date
  2014-07-25
- Invited
- Data Source
  KAKENHI-PROJECT-26550025
[Presentation] NBS1 plays a role in UV damage response through physical interaction with RAD182014
- Author(s)
  A Kato, H Yanagihara, J Kobayashi, Y Saito, D Oliveira, C Weemaes, and K Komatsu.
- Organizer
  International Symposium on Xeroderma Pigmentosum and Related Diseases
- Place of Presentation
  Kobe
- Invited
- Data Source
  KAKENHI-PROJECT-23241021
[Presentation] NBS1 plays a role in UV damage response through physical interaction with RAD182014
- Author(s)
  A Kato, H Yanagihara, J Kobayashi, Y Saito, D Oliveira, C Weemaes, and K Komatsu
- Organizer
  International Symposium on Xeroderma Pigmentosum and Related Diseases : Disorders of DNA Damage Response-Bench to Bedside-
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25550025
[Presentation] 相同組換え修復と損傷乗越えDNA合成におけるNBS1蛋白の役割2014
- Author(s)
  小松賢志、加藤晃弘、柳原啓見、斎藤裕一朗、周慧、小林純也
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25
- Invited
- Data Source
  KAKENHI-PUBLICLY-25112513
[Presentation] NBS1 plays a role in UV damage response through physical interaction with RAD18.2014
- Author(s)
  A Kato, H Yanagihara, J Kobayashi, Y Saito, D Oliveira, C Weemaes, and K Komatsu.
- Organizer
  nternational Symposium on Xeroderma Pigmentosum and Related Diseases
- Place of Presentation
  Kobe
- Invited
- Data Source
  KAKENHI-PUBLICLY-25112513
[Presentation] 紫外線損傷乗り越えDNA合成と電離放射線の修復蛋白NBS12014
- Author(s)
  小松賢志
- Organizer
  光医学・光生物学会
- Place of Presentation
  大阪
- Year and Date
  2014-07-25
- Invited
- Data Source
  KAKENHI-PROJECT-26241013
[Presentation] NBS1蛋白C末側ドメインとDNA損傷応答における役割2014
- Author(s)
  小松賢志、加藤晃弘、柳原啓見、斎藤裕一朗、周慧、小林純也
- Organizer
  日本放射線影響学会
- Place of Presentation
  鹿児島
- Year and Date
  2014-10-01
- Invited
- Data Source
  KAKENHI-PUBLICLY-25112513
[Presentation] Roles of NBS1 in radiation responses and initiation of translesional DNA synthesis2014
- Author(s)
  Kenshi Komatsu
- Organizer
  5th US-Japan DNA Repair
- Place of Presentation
  鳴門
- Year and Date
  2014-10-29
- Invited
- Data Source
  KAKENHI-PUBLICLY-25112513
[Presentation] Distinct domains of NBS1 separately function in IR- and UV-damage response2013
- Author(s)
  A Kato, H Yanagihara, K Komatsu
- Organizer
  The DNA damage response in cell physiology and disease
- Place of Presentation
  Cape Sounio(ギリシャ)
- Data Source
  KAKENHI-PROJECT-25550025
[Presentation] 若年期マウスのDNA修復能力と放射線感受性2013
- Author(s)
  小松賢志
- Organizer
  環境研セミナー
- Place of Presentation
  六ヶ所村
- Invited
- Data Source
  KAKENHI-PUBLICLY-25112513
[Presentation] NBS1による損傷乗り越えDNA合成開始機構とモデルマウスの開発2013
- Author(s)
  柳原啓見、加藤晃弘、小林純也、斎藤裕一朗、前川貴則、谷崎美智、小松賢志
- Organizer
  日本放射線影響学会第56回大会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PUBLICLY-25112513
[Presentation] 酸化ストレスによるATM キナーゼの活性制御ワークショップ「放射線生物学と活性酸素(酸化ストレス)その32013
- Author(s)
  小林純也, 藤本浩子, 奥井理予, 加藤竹雄, Martin Lavin, 松浦伸也, 小松賢志
- Organizer
  ゲノム損傷応答と細胞質酸化ストレス応答のクロストーク」・日本放射線影響学会第56回大会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-25550025
[Presentation] NBS1による損傷乗り越えDNA合成開始機構とモデルマウスの開発2013
- Author(s)
  柳原啓見、加藤晃弘、小林純也、斎藤裕一朗、前川貴則、谷崎美智、小松賢志
- Organizer
  日本放射線影響学会第56回大会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-23241021
[Presentation] NBS1による損傷乗り越えDNA合成開始機構とモデルマウスの開発2013
- Author(s)
  柳原啓見、加藤晃弘、小林純也、斎藤裕一朗、前川貴則、谷崎美智、小松賢志
- Organizer
  日本放射線影響学会第56回大会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-25550025
[Presentation] DNA 二重鎖切断端のresection 制御を通したDSB 修復機構の選択2013
- Author(s)
  小林純也, 藤本浩子, 斎藤裕一朗, 真下知士, 武田俊一, 小松賢志
- Organizer
  ワークショップ「DNA 二重鎖切断のend-resection と修復機構の選択・制御」・第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25550025
[Presentation] Distinct domains of NBS1 separately function in IR- and UV-damage response.2013
- Author(s)
  A Kato, H Yanagihara, K Komatsu
- Organizer
  The DNA damage response in cell physiology and disease
- Place of Presentation
  Cape Sounio
- Data Source
  KAKENHI-PUBLICLY-25112513
[Presentation] The role of cytoplasmic MRE11 and its relationship with ATM2013
- Author(s)
  Junya Kobayashi, Taro Kawai, Hiroko Fujimoto, Takeo Kato, Shinya Matsuura, Shizuo Akira, Kenshi Komatsu
- Organizer
  15th International Workshop on Ataxia-Telangiectasia (ATW2013)
- Place of Presentation
  Birmingham, UK
- Data Source
  KAKENHI-PROJECT-25550025
[Presentation] NBS1による損傷乗り越えDNA 合成開始機構とモデルマウスの開発2013
- Author(s)
  柳原啓見, 加藤晃弘, 小林純也, 斎藤裕一朗, 前川貴則, 谷崎美智, 小松賢志
- Organizer
  日本放射線影響学会第56回大会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-25550025
[Presentation] マウスを用いた小児期被ばくの放射線感受性とDNA 修復能の解析2013
- Author(s)
  加藤晃弘, 柳原啓見, 本田浩章, 柿沼志津子, 島田義也, 西村まゆみ, 品川まゆみ, 中村恭介, 藤本浩子, 小林純也, 小松賢志
- Organizer
  日本放射線影響学会第56回大会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-25550025
[Presentation] アルキル化損傷DNAのミスマッチ修復におけるNBS1 の役割2013
- Author(s)
  前川貴則, 柳原啓見, 小林純也, 加藤晃弘, 安井明, 小松賢志
- Organizer
  本放射線影響学会第56回大会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-25550025
[Presentation] 紫外線と放射線のDNA修復に共通した開始機構2013
- Author(s)
  小松賢志
- Organizer
  太陽紫外線防御研究会
- Place of Presentation
  神戸
- Invited
- Data Source
  KAKENHI-PROJECT-23241021
[Presentation] レポーター遺伝子を用いた生存率曲線定量モデル"Saturable Repair Model"の生物学的検証2013
- Author(s)
  斎藤裕一朗, 井原誠, 平山亮一, 加藤晃弘, 小林純也, 小松賢志
- Organizer
  日本放射線影響学会第56回大会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-25550025
[Presentation] 低線量影響とDNA 修復 -良い修復と悪い修復-2013
- Author(s)
  小松賢志
- Organizer
  保物セミナー
- Place of Presentation
  大阪市
- Year and Date
  2013-12-05
- Invited
- Data Source
  KAKENHI-PROJECT-25550025
[Presentation] Distinct domains of NBS1 separately function in IR- and UV-damage response.2013
- Author(s)
  A Kato, H Yanagihara, K Komatsu.
- Organizer
  The DNA damage response in cell physiology and disease
- Place of Presentation
  Cape Sounio
- Data Source
  KAKENHI-PROJECT-25550025
[Presentation] A Kato, H Yanagihara, K Komatsu. Distinct domains of NBS1 separately function in IR- and UV-damage response.2013
- Author(s)
  A Kato, H Yanagihara, K Komatsu
- Organizer
  The DNA damage response in cell physiology and disease
- Place of Presentation
  Cape Sounio
- Data Source
  KAKENHI-PROJECT-23241021
[Presentation] Nucleolin participates in DNA double-strand break-induced damage response through MDC1-dependent pathway2013
- Author(s)
  Junya Kobayashi, Hiroko Fujimoto, Yuichiro Saito, Ikue Hayashi, David J Chen, Kenshi Komatsu
- Organizer
  3rd Asian Congress of Radiation Research (ACRR2013)
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-25550025
[Presentation] 若年期マウスのDNA 修復能力と放射線感受性2013
- Author(s)
  小松賢志
- Organizer
  環境研セミナー
- Place of Presentation
  六ヶ所村
- Year and Date
  2013-08-30
- Invited
- Data Source
  KAKENHI-PROJECT-25550025
[Presentation] The roles of NBS1 in responses to radiation- and UV-induced DNA damage2012
- Author(s)
  Komatsu、K.
- Organizer
  The Sugahara Memorial International Symposium
- Place of Presentation
  京都大学(招待講演)
- Year and Date
  2012-01-25
- Data Source
  KAKENHI-PROJECT-23241021
[Presentation] he roles of NBS1 in responses to radiation-and UV-induced DNA damage2012
- Author(s)
  Kenshi Komatsu, Kyosuke Nakamura, Akihiro Kato, Junya Kobayashi, Hiromi Yanagihara, Douglas V. N. P. Oliveira, Mikio Shimada, Satoshi Tashiro, Shinya Matsuura, Toshio Mori, Hiroshi Tauchi
- Organizer
  The Sugahara Memorial International Symposium
- Place of Presentation
  Kyoto
- Year and Date
  2012-01-25
- Data Source
  KAKENHI-PROJECT-23651045
[Presentation] The roles of NBS1 in responses to radiation- and UV-induced DNA damage2012
- Author(s)
  Komatsu K
- Organizer
  The Sugahara Memorial International Symposium
- Place of Presentation
  京都大学(招待講演)
- Year and Date
  2012-01-25
- Data Source
  KAKENHI-PROJECT-23651045
[Presentation] DNA損傷修復研究の20年間2012
- Author(s)
  小松賢志
- Organizer
  日本放射線影響学会第55回大会
- Place of Presentation
  仙台
- Invited
- Data Source
  KAKENHI-PROJECT-23241021
[Presentation] Novel Role of NBS1 in Ubiquitination-Mediated Response through RNF202012
- Author(s)
  Junya Kobayashi, Kyosuke Nakamura, Hiromi Yanagihara, Akihiro Kato, Kenshi Komatsu
- Organizer
  14th International Workshop on Ataxia-Telangiectasia(ATW2012)
- Place of Presentation
  New Delhi(India)
- Year and Date
  2012-02-11
- Data Source
  KAKENHI-PROJECT-23651045
[Presentation] Physical and functional interaction between MRN complex and RAD512011
- Author(s)
  Akihiro Kato and Kenshi Komatsu
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-23651045
[Presentation] DNA二重鎖切断におけるクロマチン・リモデリング因子とその制御機構2011
- Author(s)
  小松賢志
- Organizer
  環境エピゲノミクス研究会第5回定例会
- Place of Presentation
  大阪府立大学
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-PROJECT-23651045
[Presentation] The link between MRN complex and RAD512011
- Author(s)
  Akihiro Kato and Kenshi Komatsu
- Organizer
  14th International Congress of Radiation Research Warsaw
- Place of Presentation
  Poland
- Year and Date
  2011-08-30
- Data Source
  KAKENHI-PROJECT-23651045
[Presentation] Ionizing radiation induced-microcephaly depends on dissociation of apical structure during embryonic development of the mouse cerebral cortex2011
- Author(s)
  Mikio Shimada, J. N. Pulvers, F. Matsuzaki, K. Komatsu
- Organizer
  14th International Congress of Radiation Research Warsaw
- Place of Presentation
  Poland
- Year and Date
  2011-08-29
- Data Source
  KAKENHI-PROJECT-23651045
[Presentation] FACT-dependent recruitment of RNF20 during DNA damage repair2011
- Author(s)
  Douglas Oliveira, Ikura T, Nakamura K, Kato A, Kobayashi J, Komatsu K
- Organizer
  EMBO Workshop, Chromosome Structure, Damage & Repair
- Place of Presentation
  Cape Sounio, Greece
- Year and Date
  2011-09-26
- Data Source
  KAKENHI-PROJECT-23651045
[Presentation] DNA二重鎖切断におけるクロマチン・リモデリング因子とその制御機構2011
- Author(s)
  Komatsu、K.
- Organizer
  環境エピゲノミクス研究会第5回定例会
- Place of Presentation
  大阪府立大学(招待講演)
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-PROJECT-23241021
[Presentation] NBS1を中心とした放射線損傷応答の最近の進歩2011
- Author(s)
  小松賢志
- Organizer
  第2回国際放射線神経生物学会
- Place of Presentation
  群馬大学
- Year and Date
  2011-12-03
- Data Source
  KAKENHI-PROJECT-23651045
[Presentation] CONTROL OF HOMOLOGUS RECOMBINATION BY RNF20-DEPENDENT H2B UBIQUITINATION2011
- Author(s)
  Komatsu K
- Organizer
  27th RBC-NIRS International Symposium
- Place of Presentation
  コープイン京都(招待講演)
- Year and Date
  2011-12-09
- Data Source
  KAKENHI-PROJECT-23651045
[Presentation] H2B ubiquitination-mediated chromatin remodeling in response to double-stranded DNA breaks in vertbrates2011
- Author(s)
  Komatsu、K.
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜(招待講演)
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-23241021
[Presentation] H2B Ubiquitination-mediated chromatin remodeling in response to double-stranded DNA breaks in vertebrates2011
- Author(s)
  Kenshi Komatsu, Kyosuke Nakamura, Akihiro Kato, Junya Kobayashi, Hiromi Yanagihara, Shuichi Sakamoto, Douglas V. N. P. Oliveira, Mikio Shimada, Satoshi Tashiro, Hiroshi Tauchi
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-23651045
[Presentation] CONTROL OF HOMOLOGOUS RECOMBINATION BY RNF20-DEPENDENT H2B UBIQUITINATION2011
- Author(s)
  Kenshi Komatsu, Kyosuke Nakamura, Akihiro Kato, Junya Kobayashi
- Organizer
  27th RBC-NIRS International Symposium
- Place of Presentation
  Kyoto
- Year and Date
  2011-12-09
- Data Source
  KAKENHI-PROJECT-23651045
[Presentation] Facilitates Chromatin Transcription complex, FACT, on DNA repair2011
- Author(s)
  Oliveira DV, Nakamura K, Kato A, Kobayashi J, Ikura T, Komatsu K
- Organizer
  第54回日本放射線影響学会
- Place of Presentation
  神戸
- Year and Date
  2011-11-18
- Data Source
  KAKENHI-PROJECT-23651045
[Presentation] NBS1を中心とした放射線損傷応答の最近の進歩2011
- Author(s)
  Komatsu、K.
- Organizer
  第2回国際放射線神経生物学会
- Place of Presentation
  群馬大学(招待講演)
- Year and Date
  2011-12-03
- Data Source
  KAKENHI-PROJECT-23241021
[Presentation] グリオーマ幹細胞のDNA修復能2011
- Author(s)
  高居邦友、宮澤浩人、小林純也、竹崎達也、秀拓一郎、平山亮一、近藤亨、小松賢志
- Organizer
  日本放射線影響学会第54回大会
- Place of Presentation
  神戸
- Year and Date
  2011-11-18
- Data Source
  KAKENHI-PROJECT-23651045
[Presentation] AT様疾患における酸化ストレスの増加はATM依存性DNA損傷応答に異常を引き起こす2011
- Author(s)
  小林純也、奥井理予、小松賢志
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23651045
[Presentation] CONTROL OF HOMOLOGOUS RECOMBINATION BY RNF20-DEPENDENT H2B UBIQUITINATION2011
- Author(s)
  Komatsu、K.
- Organizer
  27th RBC-NIRS International Symposium
- Place of Presentation
  コープ.イン.京都(招待講演)
- Year and Date
  2011-12-09
- Data Source
  KAKENHI-PROJECT-23241021
[Presentation] 酸化ストレスによるATMの活性制御2011
- Author(s)
  小林純也、奥井理予、Martin Lavin、小松賢志
- Organizer
  日本放射線影響学会第54回大会
- Place of Presentation
  神戸
- Year and Date
  2011-11-19
- Data Source
  KAKENHI-PROJECT-23651045
[Presentation] H2B ubiquitination-mediated chromatin remodeling in response to double-stranded DNA breaks in vertbrates2011
- Author(s)
  Komatsu K
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(招待講演)
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-23651045
[Presentation] Nucleolin participates in MDC1-related DNA damage response2011
- Author(s)
  Junya Kobayashi, Hiroko Fujimoto, Kenshi Komatsu
- Organizer
  14th International Congress of Radiation Research
- Place of Presentation
  Warsaw, Poland
- Year and Date
  2011-08-30
- Data Source
  KAKENHI-PROJECT-23651045
[Presentation] Nucleolin participates in MDC1-related DNA damage response2011
- Author(s)
  小林純也、藤本浩子、林幾江、小松賢志
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-23651045
[Presentation] NBS1/BRCA1-dependent ubiquitination of g-tubulin2010
- Author(s)
  K.Komatsu
- Organizer
  RBC International Symposium
- Place of Presentation
  Kyoto
- Year and Date
  2010-10-22
- Data Source
  KAKENHI-PROJECT-22651016
[Presentation] NBS1/BRCA1-dependent ubiquitination of g-tubulin2010
- Author(s)
  K.Komatsu
- Organizer
  RBC International Symposium
- Place of Presentation
  Kyoto
- Year and Date
  2010-10-22
- Data Source
  KAKENHI-PROJECT-18101002
[Presentation] Control of homologous recombination by H2B ubiquitination2010
- Author(s)
  小松賢志
- Organizer
  International Conference on Biomedical and Environmental Science & Technology
- Place of Presentation
  Beijing(招待講演)
- Year and Date
  2010-05-10
- Data Source
  KAKENHI-PROJECT-18101002
[Presentation] ヒストンH2Bユビキチン化による相同組み換え修復の制御2009
- Author(s)
  小松賢志
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜(シンポジウム、招待講演)
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-18101002
[Presentation] Control of homologous recombination by H2B ubiquitination2009
- Author(s)
  小松賢志
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜市
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-18101002
[Presentation] Control of homologous recombination by H2B ubiquitination2009
- Author(s)
  小松賢志
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜市
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-17013040
[Presentation] ヒストンH2B ユビキチン化による相同組み換え修復の制御2009
- Author(s)
  小松賢志
- Organizer
  第68回日本癌学会学術総会シンポジウム
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18101002
[Presentation] Role of NBS1 in Genome stability after genotoxic and non-genotoxic stresses2008
- Author(s)
  小松賢志
- Organizer
  Ataxia-Telangiectasia Workshop
- Place of Presentation
  大津市
- Year and Date
  2008-04-26
- Data Source
  KAKENHI-PROJECT-18101002
[Presentation] Role of NBS1 in genome stability after genotoxic and non-genotoxic stresses2008
- Author(s)
  Kenshi Komatsu
- Organizer
  Ataxia-Telangiectasia Workshop
- Place of Presentation
  Ohtsu
- Data Source
  KAKENHI-PROJECT-18101002
[Presentation] Multiple roles of NBS1 in genome stability after genotoxic and non-genotixic stresses2008
- Author(s)
  Kenshi Komatsu
- Organizer
  10th International Workshop on Radiation Damage to DNA
- Place of Presentation
  Fukushima
- Data Source
  KAKENHI-PROJECT-18101002
[Presentation] Multiple roles of NBS1 for genotonc and non-genotixic stresses2008
- Author(s)
  小松賢志
- Organizer
  10^<th> International Workshop on Radiation Damage to DNA
- Place of Presentation
  福島
- Year and Date
  2008-06-09
- Data Source
  KAKENHI-PROJECT-17013040
[Presentation] Role of NBSl in Genomic Instability.2008
- Author(s)
  小松賢志
- Organizer
  A Symposium of Radiation Biology Center at Columbia University
- Place of Presentation
  ニューヨーク
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-18101002
[Presentation] UV sensitivity of cells from Nijmegen Breakage Syndrome and the underlying mechanisms2007
- Author(s)
  Kenshi Komatsu
- Organizer
  3rd Japan-US DNA Repair Meeting
- Place of Presentation
  Sendai
- Data Source
  KAKENHI-PROJECT-18101002
[Presentation] UV sensitivities of cells from Nijmegen breakage syndrome and the UV sensitivities of cells underlying gene2007
- Author(s)
  K. Komatsu
- Organizer
  The 3rd Japan-US DNA Repair Meeting
- Place of Presentation
  Sendai
- Data Source
  KAKENHI-PROJECT-17013040
[Presentation] UV sensitivity of cells from Nijmegen Breakage Syndrome and the underlying mechanisms.2007
- Author(s)
  小松賢志, 他2名
- Organizer
  3rd Japan-US DNA Repair Meeting
- Place of Presentation
  仙台
- Year and Date
  2007-05-07
- Data Source
  KAKENHI-PROJECT-17013040
[Presentation] UV sensitivity of cells from Nijmegen Breakage Syndrome and the underlying mechanisms.2007
- Author(s)
  小松賢志, 他2名
- Organizer
  3rd Japan-US DNA Repair Meeting
- Place of Presentation
  仙台
- Year and Date
  2007-05-07
- Data Source
  KAKENHI-PROJECT-18101002
[Presentation] NBS1 foci formation and divergent roles in response to DNA damage-eliciting agents2006
- Author(s)
  Kenshi Komatsu
- Organizer
  International Workshop on Ataxia-Telangiectasia (A-T) and ATM
- Place of Presentation
  Banff, Canada
- Data Source
  KAKENHI-PROJECT-18101002
[Presentation] NBS1 foci formation and divergent roles in response to DNA damage-eliciting agents. International Workshop on Ataxia-Telangiectasia (A-T) and ATM.2006
- Author(s)
  小松賢志
- Organizer
  Banff
- Place of Presentation
  Canada(invited)
- Year and Date
  2006-09-10
- Data Source
  KAKENHI-PROJECT-18101002
[Presentation] NBS1 foci formation and divergent roles in response to DNA NBS1 foci formation and damage-eliciting agents2006
- Author(s)
  K. Komatsu
- Organizer
  The 2006 International Workshop on Ataxia-telangiectsia
- Place of Presentation
  Canada Banff
- Data Source
  KAKENHI-PROJECT-17013040
[Presentation] Human NBS1 functions in the repair of I-SCe-I-induced DSBs via Human NBS1 functions in the homologous recombination and independently of ATM2005
- Author(s)
  K. Komatsu
- Organizer
  The 2005 International Workshop on Ataxia-telangiectsia
- Place of Presentation
  Italy Milan
- Data Source
  KAKENHI-PROJECT-17013040
[Presentation] MRN複合体とRAD51の相互作用
- Author(s)
  加藤晃弘、小松賢志
- Organizer
  日本放射線影響学会第54回大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23651045
[Presentation] 若年期マウスのDNA修復能力と放射線感受性
- Author(s)
  小松賢志
- Organizer
  環境研セミナー
- Place of Presentation
  六ヶ所村
- Invited
- Data Source
  KAKENHI-PROJECT-25550025
[Presentation] 若年期マウスのDNA修復能力と放射線感受性
- Author(s)
  小松賢志
- Organizer
  環境研セミナー
- Place of Presentation
  六カ所村
- Invited
- Data Source
  KAKENHI-PROJECT-23241021

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Komatsu Kenshi 小松 賢志

KOMATSU Kenshi 小松 賢志

Research Projects

Research Products

Co-Researchers

Role of NBS1 C-terminal domain in genomic stabilityPrincipal Investigator

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The experimental verification of saturated repair model by using repair reporter genes.Principal Investigator

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多重ドメイン蛋白によるユビキチンシグナルの選択性と疾患Principal Investigator

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Review Section

Research Institution

Contribution of translesional DNA synthesis to UV-induced damage during embryogenesis and at low dose-rate.Principal Investigator

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Principal Investigator

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Roles of newly discovered NBS1 domains in ubiquitin signals and rejoining of double-strand breaks after irradiationPrincipal Investigator

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Molecular mechanism of radiation/NBS1-associated microcephalyPrincipal Investigator

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グリオブラストーマ幹細胞のDNA修復能Principal Investigator

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Induction of DNA double strand break by environmental genotoxic and carcinogenic agentsPrincipal Investigator

Principal Investigator

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FUNCTIONAL ANALYSIS OF CANCER-SUSCEPTIBIE GENE, NBS1Principal Investigator

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Origin of radiation-induced genomic instabilityPrincipal Investigator

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Research Field

Research Institution

Komatsu Kenshi 小松賢志

KOMATSU Kenshi 小松賢志